HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$126+ Cheap flights from San Francisco Bay Area to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — TYS
May 10 — May 171
Sat 5/10
Sat 5/17
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Francisco Bay Area to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from San Francisco Bay Area to Knoxville

Keep the following information in mind while searching for San Francisco Bay Area to Knoxville flight deals. Data was last updated May 5, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$255
(American Airlines)

One-way from

$126
(American Airlines)

Popular in

December

Cheapest in

August

Average price

$497
Provider with most accurate pricing for San Francisco-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Francisco-Knoxville McGhee Tyson flights.
Search Deals
From San Francisco Bay Area to Knoxville McGhee Tyson
Search Deals
One-way flight from San Francisco Bay Area to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($36 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2025
Search Deals

Find flight deals from San Francisco Bay Area to Knoxville

Cheapest flights from San Francisco Bay Area to Knoxville
Explore the most affordable flight options available from San Francisco Bay Area to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2025.

This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2812:10 pmSJC - TYS
1 stop8h 48mAmerican Airlines
Wed 6/114:09 pmTYS - SJC
2 stops9h 37mAmerican Airlines
Deal found 5/5$255
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2812:50 pmSJC - TYS
1 stop7h 49mUnited Airlines
Wed 6/114:52 pmTYS - SJC
1 stop6h 58mUnited Airlines
Deal found 5/5$276
This Mytrip deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/284:28 pmSJC - TYS
3 stops23h 56mMultiple Airlines
Wed 6/114:15 pmTYS - SJC
2 stops20h 51mMultiple Airlines
Deal found 5/5$289
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/185:23 amSFO - TYS
1 stop7h 27mAmerican Airlines
Mon 7/212:48 pmTYS - SFO
1 stop9h 54mAmerican Airlines
Deal found 5/5$309
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/217:00 amSJC - TYS
2 stops11h 27mDelta
Sun 8/245:30 amTYS - SJC
1 stop9h 06mDelta
Deal found 5/5$314
This Frontier deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/238:46 amSFO - TYS
1 stop7h 51mFrontier
Sun 10/268:22 pmTYS - SFO
1 stop6h 52mFrontier
Deal found 5/5$330
This Trip.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/511:51 amOAK - TYS
1 stop22h 49mMultiple Airlines
Mon 6/92:30 pmTYS - OAK
1 stop10h 55mMultiple Airlines
Deal found 5/4$346
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/301:41 pmSFO - TYS
1 stop7h 18mDelta
Sun 8/35:57 pmTYS - SFO
1 stop9h 43mDelta
Deal found 5/5$364
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/85:00 amSFO - TYS
1 stop7h 10mUnited Airlines
Sun 10/127:25 pmTYS - SFO
1 stop8h 34mUnited Airlines
Deal found 5/5$426
This Mytrip deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/146:09 pmSFO - TYS
2 stops25h 48mMultiple Airlines
Fri 5/236:20 amTYS - SFO
1 stop19h 38mMultiple Airlines
Deal found 5/5$473
This Alaska Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1712:17 pmSJC - TYS
1 stop8h 30mAlaska Airlines
Mon 10/202:22 pmTYS - SJC
1 stop9h 20mAlaska Airlines
Deal found 5/5$554
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/56:00 amOAK - TYS
2 stops8h 43mDelta
Mon 6/96:15 pmTYS - OAK
2 stops8h 42mDelta
Deal found 5/4$793

Cheapflights Fare Finder

Customize your flight search to find flights from San Francisco Bay Area to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2025.
Use the filters below to find and compare flights from San Francisco Bay Area to Knoxville that are best for you.

Fly from

San Francisco Bay Area

Fly to

Knoxville

Route

Depart

Return

Price

San JoseKnoxville

SJC - TYS

SJCTYS

San Jose

Wed 5/28

12:10 pm-11:58 pm

1 stop8h 48m

Knoxville McGhee Tyson

Wed 6/11

4:09 pm-10:46 pm

2 stops9h 37m

$255

San JoseKnoxville

SJC - TYS

SJCTYS

San Jose

Wed 5/28

12:50 pm-11:39 pm

1 stop7h 49m

Knoxville McGhee Tyson

Wed 6/11

4:52 pm-8:50 pm

1 stop6h 58m

$276

San JoseKnoxville

SJC - TYS

SJCTYS

San Jose

Wed 5/28

4:28 pm-7:24 pm

3 stops23h 56m

Knoxville McGhee Tyson

Wed 6/11

4:15 pm-10:06 am

2 stops20h 51m

$289

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

Fri 7/18

5:23 am-3:50 pm

1 stop7h 27m

Knoxville McGhee Tyson

Mon 7/21

2:48 pm-9:42 pm

1 stop9h 54m

$309

San JoseKnoxville

SJC - TYS

SJCTYS

San Jose

Thu 8/21

7:00 am-9:27 pm

2 stops11h 27m

Knoxville McGhee Tyson

Sun 8/24

5:30 am-11:36 am

1 stop9h 06m

$314

OaklandKnoxville

OAK - TYS

OAKTYS

Oakland

Thu 6/5

11:51 am-1:40 pm

1 stop22h 49m

Knoxville McGhee Tyson

Mon 6/9

2:30 pm-10:25 pm

1 stop10h 55m

$346

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

Thu 6/12

11:59 pm-4:11 pm

1 stop13h 12m

Knoxville McGhee Tyson

Sat 6/21

7:30 am-10:53 pm

2 stops18h 23m

$379

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

Sat 5/31

4:11 pm-10:09 am

2 stops14h 58m

Knoxville McGhee Tyson

Wed 6/4

4:52 pm-8:47 pm

1 stop6h 55m

$456

San JoseKnoxville

SJC - TYS

SJCTYS

San Jose

Fri 10/17

12:17 pm-11:47 pm

1 stop8h 30m

Knoxville McGhee Tyson

Mon 10/20

2:22 pm-8:42 pm

1 stop9h 20m

$554

OaklandKnoxville

OAK - TYS

OAKTYS

Oakland

Thu 6/5

6:00 am-5:43 pm

2 stops8h 43m

Knoxville McGhee Tyson

Mon 6/9

6:15 pm-11:57 pm

2 stops8h 42m

$793

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/4

Showing 1-10 of 22 results
1
2
3

Best time to book a flight from San Francisco Bay Area to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Francisco Bay Area with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco Bay Area to Knoxville

What is the cheapest month to book a flight from San Francisco Bay Area to Knoxville?

Currently, January is the cheapest month in which you can book a flight from San Francisco Bay Area to Knoxville (average of $296). Flying from San Francisco Bay Area to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from XIH to TYS?

Find hourly flight availability from San Francisco Bay Area to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 5, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from San Francisco Bay Area to Knoxville as you normally would.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated May 5, 2025.
Read through reviews of airlines operating flights from San Francisco Bay Area to Knoxville, such as Alaska Airlines, Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,987 reviews

Comfort

7.9

Entertainment

7.1

Food

7.1

Crew

8.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
9,987 reviews
Alaska Airlines
8.0
Very good
9,987 reviews

Comfort

7.9

Entertainment

7.1

Food

7.1

Crew

8.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,939 reviews
Alaska Airlines
8.0
Very good
9,987 reviews

Comfort

7.9

Entertainment

7.1

Food

7.1

Crew

8.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,702 reviews
Alaska Airlines
8.0
Very good
9,987 reviews

Comfort

7.9

Entertainment

7.1

Food

7.1

Crew

8.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
9,987 reviews

Comfort

7.9

Entertainment

7.1

Food

7.1

Crew

8.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from San Francisco Bay Area to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from San Francisco Bay Area?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly into when you book flights from San Francisco Bay Area to Knoxville.

  • What are the cheapest airlines to fly from San Francisco Bay Area to Knoxville one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $126. Users have also found prices from $139 and $270 on Delta and United Airlines, respectively.

  • What are the most popular routes from San Francisco Bay Area to Knoxville?

    When deciding which route to take from San Francisco Bay Area to Knoxville consider San Francisco - Knoxville McGhee Tyson, San Jose - Knoxville McGhee Tyson or Oakland - Knoxville McGhee Tyson as they are the most popular.

  • Can I find deals for flights from San Francisco Bay Area to Knoxville that include hotel bookings?

    Yes. In addition to deals on San Francisco Bay Area to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco Bay Area to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco Bay Area to Knoxville.

  • Can I find deals for business class flights from San Francisco Bay Area to Knoxville?

    Yes. Cheapflights offers flight deals from San Francisco Bay Area to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco Bay Area to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from San Francisco Bay Area to Knoxville (average of $296). Flying from San Francisco Bay Area to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco Bay Area?

Book flights to San Francisco Bay Area if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Francisco Bay Area to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to Nashville flights
San Francisco to Nashville flights
Ontario to Nashville flights
Burbank to Nashville flights
Santa Ana to Nashville flights
Los Angeles to Memphis flights
San Diego to Nashville flights
Sacramento to Nashville flights
Las Vegas to Nashville flights
Oakland to Nashville flights
San Jose to Nashville flights
Long Beach to Nashville flights
San Diego to Knoxville flights
San Francisco to Knoxville flights
Fresno to Nashville flights
Los Angeles to Knoxville flights
Ontario to Knoxville flights
Ontario to Memphis flights
Ontario to Chattanooga flights
San Francisco to Memphis flights
Reno to Knoxville flights
San Jose to Memphis flights
Burbank to Memphis flights
Palm Springs to Nashville flights
Las Vegas to Memphis flights
Los Angeles to Chattanooga flights
Ontario to Blountville flights
Reno to Nashville flights
Sacramento to Knoxville flights
Santa Ana to Chattanooga flights
Burbank to Chattanooga flights
Santa Barbara to Nashville flights
Fresno to Knoxville flights
Sacramento to Memphis flights
Oakland to Memphis flights
Santa Ana to Knoxville flights
San Luis Obispo to Nashville flights
Monterey to Nashville flights
Bakersfield to Nashville flights
San Diego to Memphis flights
San Francisco to Chattanooga flights
Santa Rosa to Nashville flights
Monterey to Memphis flights
Los Angeles to Blountville flights
San Jose to Knoxville flights
Sacramento to Blountville flights
Santa Ana to Memphis flights
Las Vegas to Knoxville flights
Burbank to Knoxville flights
Sacramento to Chattanooga flights

Top 5 airlines flying from San Francisco Bay Area to Knoxville

Discover the top 5 airlines that operate flights from San Francisco Bay Area to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$149Average$276FlexibilityNo cancel feeOn-time62%
DeltaCheapest$273Average$522FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$282Average$559FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$308Average$601FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$468Average$948FlexibilityNo cancel feeOn-time75%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.