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Knoxville

$144+ Cheap flights from San Francisco Bay Area to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/14. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — TYS
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from San Francisco Bay Area to Knoxville

Keep the following information in mind while searching for San Francisco Bay Area to Knoxville flight deals. Data was last updated September 15, 2025.

Round-trip from

$195
(Priceline)

One-way from

$144
(Delta)

Popular in

December

Cheapest in

August

Average price

$454
From San Francisco Bay Area to Knoxville McGhee Tyson
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One-way flight from San Francisco Bay Area to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 10% potential increase in price ($58 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from San Francisco Bay Area to Knoxville

Cheapest flights from San Francisco Bay Area to Knoxville
Explore the most affordable flight options available from San Francisco Bay Area to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/206:34 amSFO - TYS
1 stop9h 58mFrontier
Thu 10/238:17 pmTYS - SFO
1 stop6h 57mFrontier
Deal found 9/14$205
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:29 amSFO - TYS
1 stop10h 21mFrontier
Thu 10/98:17 pmTYS - SFO
1 stop6h 57mFrontier
Deal found 9/15$206
This Priceline deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/296:29 amSFO - TYS
1 stop10h 16mFrontier
Mon 10/68:35 pmTYS - SFO
1 stop6h 41mFrontier
Deal found 9/14$228
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/179:23 pmSFO - TYS
1 stop20h 41mMultiple Airlines
Thu 10/307:17 pmTYS - SFO
1 stop7h 57mMultiple Airlines
Deal found 9/15$230
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/158:00 amSFO - TYS
2 stops34h 07mMultiple Airlines
Thu 10/307:17 pmTYS - SFO
1 stop7h 57mMultiple Airlines
Deal found 9/15$263
This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:34 amSFO - TYS
1 stop9h 58mFrontier
Mon 10/278:17 pmTYS - SFO
1 stop6h 57mFrontier
Deal found 9/15$265
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/141:15 pmSJC - TYS
1 stop8h 08mAmerican Airlines
Tue 10/2812:35 pmTYS - SJC
1 stop7h 18mAmerican Airlines
Deal found 9/15$269
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/710:25 pmSJC - TYS
1 stop7h 35mDelta
Sat 10/256:15 amTYS - SJC
1 stop8h 02mDelta
Deal found 9/15$277
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:59 pmSJC - TYS
2 stops11h 01mDelta
Sat 10/256:15 amTYS - SJC
1 stop8h 02mDelta
Deal found 9/15$282
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/179:23 pmSFO - TYS
1 stop20h 41mMultiple Airlines
Fri 10/315:44 pmTYS - SFO
2 stops31h 43mMultiple Airlines
Deal found 9/15$286
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:59 pmSJC - TYS
2 stops11h 01mDelta
Wed 10/295:44 amTYS - SJC
2 stops9h 34mDelta
Deal found 9/15$287
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/124:55 pmSFO - TYS
2 stops27h 21mMultiple Airlines
Thu 10/307:17 pmTYS - SFO
1 stop7h 57mMultiple Airlines
Deal found 9/15$298

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco Bay Area to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from San Francisco Bay Area to Knoxville that are best for you.

Fly from

San Francisco Bay Area

Fly to

Knoxville

Route

Depart

Return

Price

San JoseKnoxville

SJC - TYS

SJCTYS

San Jose

Tue 10/14

6:59 pm-9:00 am

2 stops11h 01m

Knoxville McGhee Tyson

Wed 10/22

6:40 am-12:24 pm

1 stop8h 44m

$282

San JoseKnoxville

SJC - TYS

SJCTYS

San Jose

Tue 10/7

8:10 pm-9:00 am

2 stops9h 50m

Knoxville McGhee Tyson

Sat 10/25

6:15 am-2:42 pm

2 stops11h 27m

$287

San JoseKnoxville

SJC - TYS

SJCTYS

San Jose

Tue 10/7

6:59 pm-9:00 am

2 stops11h 01m

Knoxville McGhee Tyson

Tue 10/21

5:44 am-12:50 pm

2 stops10h 06m

$287

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

Sun 10/12

4:55 pm-11:16 pm

2 stops27h 21m

Knoxville McGhee Tyson

Thu 10/30

7:17 pm-12:14 am

1 stop7h 57m

$298

San JoseKnoxville

SJC - TYS

SJCTYS

San Jose

Mon 10/13

6:35 am-7:05 pm

1 stop9h 30m

Knoxville McGhee Tyson

Wed 10/29

6:40 am-12:24 pm

1 stop8h 44m

$303

San JoseKnoxville

SJC - TYS

SJCTYS

San Jose

Tue 10/14

6:59 pm-9:00 am

2 stops11h 01m

Knoxville McGhee Tyson

Fri 10/31

5:44 am-2:47 pm

2 stops12h 03m

$307

San JoseKnoxville

SJC - TYS

SJCTYS

San Jose

Mon 10/13

6:59 pm-9:20 am

2 stops11h 21m

Knoxville McGhee Tyson

Tue 10/21

3:48 pm-7:59 pm

1 stop7h 11m

$308

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

Tue 10/14

9:50 pm-9:00 am

1 stop8h 10m

Knoxville McGhee Tyson

Fri 10/24

5:44 am-9:58 am

1 stop7h 14m

$329

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

Tue 10/14

9:50 pm-9:00 am

1 stop8h 10m

Knoxville McGhee Tyson

Wed 10/29

6:40 am-1:30 pm

1 stop9h 50m

$329

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

Tue 10/14

9:50 pm-9:00 am

1 stop8h 10m

Knoxville McGhee Tyson

Fri 10/31

7:45 am-2:13 pm

1 stop9h 28m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 47 results
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Best time to book a flight from San Francisco Bay Area to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Francisco Bay Area with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco Bay Area to Knoxville

What is the cheapest month to book a flight from San Francisco Bay Area to Knoxville?

Currently, January is the cheapest month in which you can book a flight from San Francisco Bay Area to Knoxville (average of $295). Flying from San Francisco Bay Area to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from XIH to TYS?

Find hourly flight availability from San Francisco Bay Area to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from San Francisco Bay Area to Knoxville as you normally would.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 15, 2025.
Read reviews from past customers who have flown Alaska Airlines, Delta, and United Airlines from San Francisco Bay Area to Knoxville. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Food

7.1

Overall

8.0

Boarding

8.1

Crew

8.5

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Food

7.1

Overall

8.0

Boarding

8.1

Crew

8.5

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Delta
8.0
Very good
7,954 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Food

7.1

Overall

8.0

Boarding

8.1

Crew

8.5

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
United Airlines
7.4
Good
8,929 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Food

7.1

Overall

8.0

Boarding

8.1

Crew

8.5

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Food

7.1

Overall

8.0

Boarding

8.1

Crew

8.5

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Frontier
5.8
Fair
3,172 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Food

7.1

Overall

8.0

Boarding

8.1

Crew

8.5

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from San Francisco Bay Area to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from San Francisco Bay Area?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly into when you book flights from San Francisco Bay Area to Knoxville.

  • How long is the flight from San Francisco Bay Area to Knoxville?

    A quick flight from San Francisco Bay Area to Knoxville can take about 8h 39m. Delta provides one of the quickest options available for as low as $334. The distance between San Francisco Bay Area and Knoxville is about 2114 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from San Francisco Bay Area to Knoxville?

    When deciding which route to take from San Francisco Bay Area to Knoxville consider San Francisco - Knoxville McGhee Tyson, San Jose - Knoxville McGhee Tyson or Oakland - Knoxville McGhee Tyson as they are the most popular.

  • Can I find deals for flights from San Francisco Bay Area to Knoxville that include hotel bookings?

    Yes. In addition to deals on San Francisco Bay Area to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco Bay Area to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco Bay Area to Knoxville.

  • Can I find deals for business class flights from San Francisco Bay Area to Knoxville?

    Yes. Cheapflights offers flight deals from San Francisco Bay Area to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco Bay Area to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from San Francisco Bay Area to Knoxville (average of $295). Flying from San Francisco Bay Area to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Alternative routes for San Francisco Bay Area to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from San Francisco Bay Area to Knoxville

Discover the top 5 airlines that operate flights from San Francisco Bay Area to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$138Average$278FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$256Average$556FlexibilityNo cancel feeOn-time71%
DeltaCheapest$268Average$396FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$299Average$552FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$409Average$948FlexibilityNo cancel feeOn-time75%

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