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$130+ Cheap flights from San Francisco Bay Area to Knoxville (TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — TYS
Dec 4 — Dec 111
Thu 12/4
Thu 12/11
1 adult, Economy
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Cheap flight deals from San Francisco Bay Area to Knoxville

Keep the following information in mind while searching for San Francisco Bay Area to Knoxville flight deals. Data was last updated November 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$130
(Priceline)

Popular in

December

Cheapest in

August

Average price

$512
Provider with most accurate pricing for San Francisco-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for San Francisco-Knoxville McGhee Tyson flights.
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From San Francisco Bay Area to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 10% potential increase in price ($56 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from San Francisco Bay Area to Knoxville

Cheapest flights from San Francisco Bay Area to Knoxville
Explore the most affordable flight options available from San Francisco Bay Area to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2025.

This Priceline deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:30 amSFO - TYS
1 stop6h 27mFrontier
Thu 1/154:23 pmTYS - SFO
1 stop11h 06mFrontier
Deal found 11/1$130
This Frontier deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:30 amSFO - TYS
1 stop6h 27mFrontier
Mon 12/154:52 pmTYS - SFO
1 stop10h 32mFrontier
Deal found 11/3$234
This Priceline deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:30 amSFO - TYS
1 stop6h 27mFrontier
Mon 12/84:52 pmTYS - SFO
1 stop10h 32mFrontier
Deal found 11/2$236
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/44:07 pmSFO - TYS
2 stops26h 42mMultiple Airlines
Mon 12/84:52 pmTYS - SFO
1 stop10h 32mMultiple Airlines
Deal found 11/2$258
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1610:10 pmSFO - TYS
2 stops38h 21mMultiple Airlines
Wed 12/241:58 pmTYS - SFO
1 stop13h 26mMultiple Airlines
Deal found 11/1$292
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/38:15 amSFO - TYS
1 stop7h 43mDelta
Sun 12/77:59 pmTYS - SFO
1 stop7h 21mDelta
Deal found 11/3$329
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/512:20 pmSFO - TYS
2 stops8h 39mAmerican Airlines
Wed 12/108:06 amTYS - SFO
1 stop9h 02mAmerican Airlines
Deal found 11/2$334
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:00 amSJC - TYS
1 stop8h 27mAmerican Airlines
Tue 1/64:41 pmTYS - SJC
1 stop7h 48mAmerican Airlines
Deal found 11/4$367
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:00 amSFO - TYS
1 stop8h 20mAmerican Airlines
Thu 12/46:20 pmTYS - SFO
1 stop7h 32mAmerican Airlines
Deal found 11/3$369
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/272:54 pmSFO - TYS
1 stop21h 59mMultiple Airlines
Mon 12/15:19 pmTYS - SFO
2 stops26h 32mMultiple Airlines
Deal found 11/4$372
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:35 amSJC - TYS
1 stop9h 23mDelta
Tue 1/65:30 amTYS - SJC
2 stops10h 35mDelta
Deal found 11/3$372
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:34 amSFO - TYS
1 stop8h 48mMultiple Airlines
Sun 11/161:16 pmTYS - SFO
2 stops35h 19mMultiple Airlines
Deal found 11/1$393

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco Bay Area to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from San Francisco Bay Area to Knoxville that are best for you.

Fly from

San Francisco Bay Area

Fly to

Knoxville

Route

Depart

Return

Price

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

Mon 12/15

6:30 am-3:57 pm

1 stop6h 27m

Knoxville McGhee Tyson

Thu 1/15

4:23 pm-11:53 pm

2 stops34h 30m

$297

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

Tue 1/6

1:19 pm-8:39 am

2 stops40h 20m

Knoxville McGhee Tyson

Thu 1/15

4:23 pm-12:29 am

1 stop11h 06m

$319

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

Thu 12/4

11:56 am-11:18 pm

1 stop8h 22m

Knoxville McGhee Tyson

Sat 12/6

7:30 am-2:23 pm

1 stop9h 53m

$329

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

Tue 3/10

11:20 pm-10:48 am

1 stop8h 28m

Knoxville McGhee Tyson

Tue 3/17

7:00 am-11:51 am

1 stop7h 51m

$329

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

Sat 4/25

1:45 pm-11:46 pm

1 stop7h 01m

Knoxville McGhee Tyson

Wed 4/29

7:30 am-2:29 pm

1 stop9h 59m

$329

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

Tue 1/6

10:35 pm-10:57 am

1 stop9h 22m

Knoxville McGhee Tyson

Thu 1/15

11:07 am-3:35 pm

1 stop7h 28m

$329

San JoseKnoxville

SJC - TYS

SJCTYS

San Jose

Wed 12/17

6:00 am-5:27 pm

1 stop8h 27m

Knoxville McGhee Tyson

Tue 1/6

4:41 pm-9:29 pm

1 stop7h 48m

$367

San JoseKnoxville

SJC - TYS

SJCTYS

San Jose

Sat 2/21

1:48 pm-11:50 pm

1 stop7h 02m

Knoxville McGhee Tyson

Wed 2/25

5:00 pm-9:20 pm

1 stop7h 20m

$367

San JoseKnoxville

SJC - TYS

SJCTYS

San Jose

Wed 12/3

6:35 am-4:53 pm

1 stop7h 18m

Knoxville McGhee Tyson

Sat 12/13

3:50 pm-10:55 pm

1 stop10h 05m

$367

San JoseKnoxville

SJC - TYS

SJCTYS

San Jose

Wed 12/17

6:35 am-6:58 pm

1 stop9h 23m

Knoxville McGhee Tyson

Tue 1/6

5:30 am-1:05 pm

2 stops10h 35m

$372

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 40 results
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Best time to book a flight from San Francisco Bay Area to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Francisco Bay Area with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco Bay Area to Knoxville

What is the cheapest month to book a flight from San Francisco Bay Area to Knoxville?

Currently, May is the cheapest month in which you can book a flight from San Francisco Bay Area to Knoxville (average of $138). Flying from San Francisco Bay Area to Knoxville in December is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from XIH to TYS?

Find hourly flight availability from San Francisco Bay Area to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 4, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 35% on flights from San Francisco Bay Area to Knoxville by exploring options for tickets in the evening.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated November 4, 2025.
Read reviews from past customers who have flown Alaska Airlines, Delta, and United Airlines from San Francisco Bay Area to Knoxville. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,241 reviews

Food

7.1

Overall

8.0

Boarding

8.1

Comfort

7.8

Crew

8.5

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
11,241 reviews
Alaska Airlines
8.0
Very good
11,241 reviews

Food

7.1

Overall

8.0

Boarding

8.1

Comfort

7.8

Crew

8.5

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Delta
7.9
Good
8,004 reviews
Alaska Airlines
8.0
Very good
11,241 reviews

Food

7.1

Overall

8.0

Boarding

8.1

Comfort

7.8

Crew

8.5

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
United Airlines
7.4
Good
9,001 reviews
Alaska Airlines
8.0
Very good
11,241 reviews

Food

7.1

Overall

8.0

Boarding

8.1

Comfort

7.8

Crew

8.5

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
American Airlines
7.2
Good
11,039 reviews
Alaska Airlines
8.0
Very good
11,241 reviews

Food

7.1

Overall

8.0

Boarding

8.1

Comfort

7.8

Crew

8.5

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Frontier
5.8
Fair
3,115 reviews
Alaska Airlines
8.0
Very good
11,241 reviews

Food

7.1

Overall

8.0

Boarding

8.1

Comfort

7.8

Crew

8.5

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from San Francisco Bay Area to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from San Francisco Bay Area?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly into when you book flights from San Francisco Bay Area to Knoxville.

  • How long is the flight from San Francisco Bay Area to Knoxville?

    A quick flight from San Francisco Bay Area to Knoxville can take about 6h 27m. Frontier provides one of the quickest options available for as low as $297. The distance between San Francisco Bay Area and Knoxville is about 2114 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from San Francisco Bay Area to Knoxville one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $161. Users have also found prices from $219 and $224 on United Airlines and American Airlines, respectively.

  • What are the most popular routes from San Francisco Bay Area to Knoxville?

    When deciding which route to take from San Francisco Bay Area to Knoxville consider San Francisco - Knoxville McGhee Tyson, San Jose - Knoxville McGhee Tyson or Oakland - Knoxville McGhee Tyson as they are the most popular.

  • Can I find deals for flights from San Francisco Bay Area to Knoxville that include hotel bookings?

    Yes. In addition to deals on San Francisco Bay Area to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco Bay Area to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco Bay Area to Knoxville.

  • Can I find deals for business class flights from San Francisco Bay Area to Knoxville?

    Yes. Cheapflights offers flight deals from San Francisco Bay Area to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco Bay Area to Knoxville?

    Currently, May is the cheapest month in which you can book a flight from San Francisco Bay Area to Knoxville (average of $138). Flying from San Francisco Bay Area to Knoxville in December is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

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Alternative routes for San Francisco Bay Area to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from San Francisco Bay Area to Knoxville

Discover the top 5 airlines that operate flights from San Francisco Bay Area to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$149Average$276FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$256Average$544FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$280Average$507FlexibilityNo cancel feeOn-time69%
DeltaCheapest$298Average$415FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$409Average$718FlexibilityNo cancel feeOn-time75%

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