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Knoxville

$384+ Cheap flights from Quito (UIO) to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel.
UIO — TYS
May 1 — May 81
Fri 5/1
Fri 5/8
1 adult, Economy
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Cheap flight deals from Quito to Knoxville

Cheapest flights from Quito to Knoxville
Explore the most affordable flight options available from Quito to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2026.

This eDestinos deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2512:59 am
UIO
-
TYS
2 stops39h 31m
Multiple Airlines
Sat 5/211:56 am
TYS
-
UIO
1 stop17h 47m
Multiple Airlines
Deal found 3/30$615
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/175:25 pm
UIO
-
TYS
1 stop17h 30m
Multiple Airlines
Mon 8/171:07 pm
TYS
-
UIO
2 stops14h 48m
Multiple Airlines
Deal found 3/27$671
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1612:35 am
UIO
-
TYS
2 stops15h 19m
United Airlines
Mon 8/175:57 pm
TYS
-
UIO
2 stops12h 03m
United Airlines
Deal found 3/27$736
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1711:40 pm
UIO
-
TYS
1 stop23h 19m
American Airlines
Mon 8/177:00 am
TYS
-
UIO
1 stop14h 58m
American Airlines
Deal found 3/27$781
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:40 pm
UIO
-
TYS
2 stops14h 46m
American Airlines
Sun 8/165:13 am
TYS
-
UIO
2 stops16h 45m
American Airlines
Deal found 3/31$802
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:30 am
UIO
-
TYS
1 stop16h 29m
American Airlines
Thu 10/15:40 am
TYS
-
UIO
1 stop14h 05m
American Airlines
Deal found 3/29$850
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:30 pm
UIO
-
TYS
2 stops41h 59m
Multiple Airlines
Mon 11/27:10 am
TYS
-
UIO
1 stop23h 45m
Multiple Airlines
Deal found 3/27$902
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/267:25 am
UIO
-
TYS
2 stops30h 44m
United Airlines
Sat 5/27:00 am
TYS
-
UIO
2 stops17h 25m
United Airlines
Deal found 3/30$919

Find flight deals from Quito to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Quito (UIO) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$615
(eDestinos)

One-way from

$384
(Kiwi.com)
Provider with most accurate pricing for Quito Mariscal Sucr-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Quito Mariscal Sucr-Knoxville McGhee Tyson flights.
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From Quito Mariscal Sucr to Knoxville McGhee Tyson
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One-way flight from Quito Mariscal Sucr to Knoxville McGhee Tyson
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Quito to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Quito to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Sun 4/26

5:25 pm-11:55 am

1 stop17h 30m

Knoxville McGhee Tyson

Sat 5/2

1:59 pm-8:40 am

2 stops19h 41m

$647

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Sun 5/17

5:25 pm-11:55 am

1 stop17h 30m

Knoxville McGhee Tyson

Mon 8/17

1:07 pm-2:55 am

2 stops14h 48m

$671
Quickest round-trip

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Sat 5/16

12:35 am-4:54 pm

2 stops15h 19m

Knoxville McGhee Tyson

Mon 8/17

5:57 pm-5:00 am

2 stops12h 03m

$736

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Sun 5/17

11:40 pm-11:59 pm

1 stop23h 19m

Knoxville McGhee Tyson

Mon 8/17

7:00 am-8:58 pm

1 stop14h 58m

$781

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Sat 5/16

11:40 pm-3:26 pm

2 stops14h 46m

Knoxville McGhee Tyson

Sun 8/16

5:13 am-8:58 pm

2 stops16h 45m

$802

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Tue 7/14

6:30 am-9:32 pm

2 stops14h 02m

Knoxville McGhee Tyson

Thu 10/1

5:40 am-6:45 pm

1 stop14h 05m

$855

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Sun 4/26

7:25 am-1:49 pm

1 stop29h 24m

Knoxville McGhee Tyson

Sat 5/2

11:40 am-11:25 pm

1 stop12h 45m

$919

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Wed 4/15

12:35 am-7:42 pm

2 stops18h 07m

Knoxville McGhee Tyson

Mon 4/20

7:05 am-11:25 pm

1 stop17h 20m

$1,010
Cheapest one-way
Quickest one-way

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Mon 4/6

2:30 pm-4:04 pm

2 stops24h 34m

$384

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Mon 4/6

7:25 am-1:49 pm

1 stop29h 24m

$667

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Quito-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Quito-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Quito-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Quito-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Quito-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Quito to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Quito with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Quito to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Quito to Knoxville?

    For as low as $736, United Airlines can have you in Knoxville from Quito in 15h 19m. There are 2507 mi between Quito and Knoxville. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Quito to Knoxville that include hotel bookings?

    Yes. In addition to deals on Quito to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Quito to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Quito to Knoxville.

  • Can I find deals for business class flights from Quito to Knoxville?

    Yes. Cheapflights offers flight deals from Quito to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

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