HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$319+ Cheap flights from Quito (UIO) to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
UIO — TYS
Apr 2 — Apr 91
Thu 4/2
Thu 4/9
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Quito to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Quito to Knoxville

Cheapest flights from Quito to Knoxville
Explore the most affordable flight options available from Quito to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 3, 2026.

This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:35 am
UIO
-
TYS
2 stops39h 19m
United Airlines
Thu 8/206:30 am
TYS
-
UIO
2 stops17h 55m
United Airlines
Deal found 2/27$696
This American Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:05 am
UIO
-
TYS
1 stop15h 54m
American Airlines
Thu 8/207:00 am
TYS
-
UIO
1 stop17h 55m
American Airlines
Deal found 2/27$709
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:35 am
UIO
-
TYS
2 stops20h 59m
United Airlines
Thu 4/237:05 am
TYS
-
UIO
1 stop17h 20m
United Airlines
Deal found 3/2$712
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:05 am
UIO
-
TYS
1 stop15h 54m
American Airlines
Thu 4/236:30 am
TYS
-
UIO
1 stop14h 27m
American Airlines
Deal found 3/2$740
This BusinessClass deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:50 pm
UIO
-
TYS
2 stops18h 43m
LATAM Airlines
Thu 8/204:00 pm
TYS
-
UIO
2 stops13h 43m
LATAM Airlines
Deal found 3/1$756
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:50 pm
UIO
-
TYS
2 stops17h 20m
Delta
Thu 8/206:10 am
TYS
-
UIO
2 stops23h 33m
Delta
Deal found 3/1$767

Find flight deals from Quito to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Quito (UIO) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$696
(United Airlines)

One-way from

$319
(Kiwi.com)
Provider with most accurate pricing for Quito Mariscal Sucr-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Quito Mariscal Sucr-Knoxville McGhee Tyson flights.
Search Deals
From Quito Mariscal Sucr to Knoxville McGhee Tyson
Search Deals
One-way flight from Quito Mariscal Sucr to Knoxville McGhee Tyson
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Quito to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 3, 2026.
Use the filters below to find and compare flights from Quito to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Wed 5/13

12:35 am-4:54 pm

2 stops39h 19m

Knoxville McGhee Tyson

Thu 8/20

7:15 am-11:25 pm

1 stop17h 10m

$696

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Wed 4/15

12:35 am-10:34 pm

2 stops20h 59m

Knoxville McGhee Tyson

Thu 4/23

7:05 am-11:25 pm

1 stop17h 20m

$712

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Thu 5/14

7:05 am-11:59 pm

1 stop15h 54m

Knoxville McGhee Tyson

Thu 8/20

12:20 pm-11:55 pm

2 stops12h 35m

$725

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Thu 5/14

6:50 pm-2:33 pm

2 stops18h 43m

Knoxville McGhee Tyson

Thu 8/20

11:55 am-4:43 am

2 stops17h 48m

$776

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Wed 4/29

12:35 am-8:45 pm

2 stops19h 10m

Knoxville McGhee Tyson

Mon 5/4

7:05 am-11:25 pm

1 stop17h 20m

$836

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Fri 6/26

4:45 am-11:34 pm

3 stops17h 49m

$485

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Sat 3/14

7:05 pm-8:08 am

3 stops36h 03m

$521

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Fri 6/26

7:25 am-11:12 pm

1 stop14h 47m

$532

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Sat 3/14

11:45 pm-4:06 pm

1 stop15h 21m

$999

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/27

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Quito-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Quito-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Quito-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Quito-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Quito-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Quito to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Quito with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Quito to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Quito to Knoxville?

    For as low as $696, United Airlines can have you in Knoxville from Quito in 39h 19m. There are 2507 mi between Quito and Knoxville.

  • Can I find deals for flights from Quito to Knoxville that include hotel bookings?

    Yes. In addition to deals on Quito to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Quito to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Quito to Knoxville.

  • Can I find deals for business class flights from Quito to Knoxville?

    Yes. Cheapflights offers flight deals from Quito to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Quito to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Quito to Nashville flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.