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$393+ Cheap flights from Quito (UIO) to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
UIO — TYS
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Quito to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Quito (UIO) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$675
(United Airlines)

One-way from

$433
(FlightHub)

Popular in

March

Cheapest in

September

Average price

$623
From Quito Mariscal Sucr to Knoxville McGhee Tyson
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One-way flight from Quito Mariscal Sucr to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 1% potential increase in price ($14 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Quito to Knoxville

Cheapest flights from Quito to Knoxville
Explore the most affordable flight options available from Quito to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2812:35 amUIO - TYS
2 stops22h 24mUnited Airlines
Wed 11/57:20 pmTYS - UIO
2 stops29h 10mUnited Airlines
Deal found 9/9$675
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2812:55 amUIO - TYS
1 stop12h 48mDelta
Wed 11/55:44 amTYS - UIO
2 stops13h 21mDelta
Deal found 9/9$737
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:30 amUIO - TYS
2 stops15h 40mAmerican Airlines
Wed 11/55:10 amTYS - UIO
2 stops14h 49mAmerican Airlines
Deal found 9/9$760

Cheapflights Fare Finder

 
Customize your flight search to find flights from Quito to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Quito to Knoxville that are best for you.

Fly from

Quito

Fly to

Knoxville

Route

Depart

Return

Price

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Tue 10/28

12:35 am-11:59 pm

2 stops22h 24m

Knoxville McGhee Tyson

Wed 11/5

7:20 pm-12:30 am

2 stops29h 10m

$675

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Tue 10/28

12:55 am-2:43 pm

1 stop12h 48m

Knoxville McGhee Tyson

Wed 11/5

5:44 am-7:05 pm

2 stops13h 21m

$737

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Wed 10/29

6:30 am-11:10 pm

2 stops15h 40m

Knoxville McGhee Tyson

Wed 11/5

6:00 am-11:04 pm

1 stop17h 04m

$760

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Tue 10/7

6:03 am-2:30 pm

2 stops31h 27m

$393

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Tue 10/7

6:30 am-11:39 pm

1 stop16h 09m

$583

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Mon 10/6

12:59 am-8:10 pm

1 stop18h 11m

$636

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Best time to book a flight from Quito to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Quito with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Quito to Knoxville

What is the cheapest time of day to fly from UIO to TYS?

Find hourly flight availability from Quito to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Quito to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 11, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Quito to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

Related info for your journey

Find useful and relevant information for your journey from Quito to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Quito to Knoxville?

    For as low as $737, United Airlines can have you in Knoxville from Quito in 12h 48m. There are 2507 mi between Quito and Knoxville. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Quito to Knoxville round-trip?

    Currently priced at $622, Delta will fly you from Quito to Knoxville and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $720. Delta is priced at 16% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Quito to Knoxville that include hotel bookings?

    Yes. In addition to deals on Quito to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Quito to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Quito to Knoxville.

  • Can I find deals for business class flights from Quito to Knoxville?

    Yes. Cheapflights offers flight deals from Quito to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Quito to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Quito to Knoxville (average of $294). Flying from Quito to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Alternative routes for Quito to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Quito to Knoxville

Discover the top 2 airlines that operate flights from Quito to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$622Average$786FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$720Average$852FlexibilityNo cancel feeOn-time71%

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