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Knoxville

$530+ Cheap flights from Quito (UIO) to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/11. Fares are subject to change and may not be available on all flights or dates of travel.
UIO — TYS
May 5 — May 121
Tue 5/5
Tue 5/12
1 adult, Economy
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Cheap flight deals from Quito to Knoxville

Cheapest flights from Quito to Knoxville
Explore the most affordable flight options available from Quito to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 5, 2026.

This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:40 pm
UIO
-
TYS
2 stops14h 46m
American Airlines
Sun 8/165:13 am
TYS
-
UIO
2 stops16h 45m
American Airlines
Deal found 3/31$802
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:50 pm
UIO
-
TYS
2 stops15h 19m
Delta
Sun 9/275:30 am
TYS
-
UIO
1 stop14h 29m
Delta
Deal found 4/2$824
This BusinessClass deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:59 am
UIO
-
TYS
1 stop9h 10m
LATAM Airlines
Sat 8/154:00 pm
TYS
-
UIO
1 stop27h 59m
LATAM Airlines
Deal found 4/1$832
This Faresmojo deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3012:59 am
UIO
-
TYS
1 stop17h 08m
JetBlue
Sun 9/278:47 am
TYS
-
UIO
1 stop11h 12m
JetBlue
Deal found 4/2$851
This BusinessClass deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:50 pm
UIO
-
TYS
2 stops15h 19m
LATAM Airlines
Sun 9/275:57 pm
TYS
-
UIO
2 stops11h 46m
LATAM Airlines
Deal found 4/3$853
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:00 am
UIO
-
TYS
1 stop16h 59m
American Airlines
Thu 10/87:13 am
TYS
-
UIO
1 stop14h 27m
American Airlines
Deal found 4/2$868
This Expedia deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:50 pm
UIO
-
TYS
2 stops26h 49m
LATAM Airlines
Thu 10/87:20 pm
TYS
-
UIO
2 stops34h 23m
LATAM Airlines
Deal found 4/2$887
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3012:35 am
UIO
-
TYS
2 stops31h 58m
United Airlines
Sun 9/277:35 pm
TYS
-
UIO
2 stops52h 50m
United Airlines
Deal found 4/2$916
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:00 am
UIO
-
TYS
1 stop16h 59m
American Airlines
Sun 9/275:40 am
TYS
-
UIO
1 stop14h 05m
American Airlines
Deal found 4/3$923

Find flight deals from Quito to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Quito (UIO) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$802
(American Airlines)

One-way from

$530
(Kiwi.com)
Provider with most accurate pricing for Quito Mariscal Sucr-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Quito Mariscal Sucr-Knoxville McGhee Tyson flights.
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From Quito Mariscal Sucr to Knoxville McGhee Tyson
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One-way flight from Quito Mariscal Sucr to Knoxville McGhee Tyson
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Quito to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 5, 2026.
Use the filters below to find and compare flights from Quito to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Sat 5/16

11:40 pm-3:26 pm

2 stops14h 46m

Knoxville McGhee Tyson

Sun 8/16

5:13 am-8:58 pm

2 stops16h 45m

$802

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Sat 5/16

11:40 pm-5:07 pm

2 stops16h 27m

Knoxville McGhee Tyson

Sat 8/15

5:13 am-8:58 pm

2 stops16h 45m

$802
Quickest round-trip

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Wed 7/1

6:50 pm-11:09 am

2 stops15h 19m

Knoxville McGhee Tyson

Sun 9/27

5:57 pm-4:43 am

2 stops11h 46m

$853

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Fri 7/31

6:50 pm-10:39 pm

2 stops26h 49m

Knoxville McGhee Tyson

Thu 10/8

7:20 pm-4:43 am

2 stops34h 23m

$887

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Tue 6/30

12:35 am-9:33 am

2 stops31h 58m

Knoxville McGhee Tyson

Sun 9/27

7:35 pm-11:25 pm

2 stops52h 50m

$916

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Tue 4/21

12:35 am-7:56 pm

1 stop18h 21m

Knoxville McGhee Tyson

Sun 4/26

9:40 am-11:25 pm

2 stops38h 45m

$1,017

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Wed 8/26

12:59 am-6:17 pm

1 stop16h 18m

Knoxville McGhee Tyson

Wed 12/16

12:00 pm-11:00 pm

2 stops11h 00m

$1,086
Cheapest one-way
Quickest one-way

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Thu 6/11

6:40 pm-6:32 pm

2 stops22h 52m

$530

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/1

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Quito-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Quito-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Quito-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Quito-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Quito-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Quito to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Quito with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Quito to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Quito to Knoxville?

    For as low as $802, American Airlines can have you in Knoxville from Quito in 14h 46m. There are 2507 mi between Quito and Knoxville. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Quito to Knoxville that include hotel bookings?

    Yes. In addition to deals on Quito to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Quito to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Quito to Knoxville.

  • Can I find deals for business class flights from Quito to Knoxville?

    Yes. Cheapflights offers flight deals from Quito to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

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