$105+ Cheap flights from Columbus (CMH) to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — TYS
Oct 4 — Oct 111
Round-trip
1 adult, Economy
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Find cheap flights from Columbus to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbus to Knoxville
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Cheapest flights from Columbus to KnoxvilleExplore the most affordable flight options available from Columbus to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 4, 2026.
Explore the most affordable flight options available from Columbus to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 4, 2026.
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:02 am -
1 stop4h 35m
Sat 10/2410:42 am -
1 stop6h 23m
Deal found 9/2![United Airlines logo]()
$273
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:50 am -
1 stop5h 15m
Wed 9/307:00 am -
2 stops7h 55m
Deal found 9/2![Southwest logo]()
$278
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:15 pm -
1 stop4h 40m
Wed 10/78:20 am -
2 stops11h 50m
Deal found 8/31![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am -
1 stop3h 34m
Fri 10/237:45 pm -
1 stop4h 59m
Deal found 9/1![Delta logo]()
$288
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:50 am -
2 stops5h 30m
Sat 10/316:40 am -
2 stops10h 40m
Deal found 9/3![Southwest logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:44 pm -
2 stops25h 37m
Thu 10/229:11 pm -
1 stop21h 44m
Deal found 8/31![Multiple Airlines logo]()
$292
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:35 pm -
2 stops6h 30m
Sat 10/318:25 am -
1 stop3h 40m
Deal found 9/3![Southwest logo]()
$293
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:55 am -
1 stop10h 15m
Sat 10/246:40 am -
2 stops5h 45m
Deal found 9/2![Southwest logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/49:16 pm -
1 stop13h 28m
Sun 10/117:58 pm -
2 stops46h 50m
Deal found 9/3![Multiple Airlines logo]()
$306
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:50 pm -
2 stops6h 55m
Fri 10/237:25 pm -
1 stop3h 25m
Deal found 9/1![Southwest logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:50 pm -
2 stops20h 53m
Wed 9/3010:28 am -
1 stop10h 03m
Deal found 8/31![Multiple Airlines logo]()
$309
Best flights from Columbus to KnoxvilleDiscover carefully curated flight deals from Columbus to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 4, 2026.
Discover carefully curated flight deals from Columbus to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 4, 2026.
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:15 pm -
1 stop4h 40m
Wed 10/78:20 am -
1 stop4h 00m
Deal found 8/31![Southwest logo]()
$273
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:25 am -
1 stop3h 55m
Wed 10/72:38 pm -
1 stop5h 55m
Deal found 9/2![Delta logo]()
$273
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:20 am -
1 stop4h 25m
Sun 10/255:45 am -
1 stop4h 10m
Deal found 9/1![United Airlines logo]()
$404
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/173:45 pm -
1 stop3h 55m
Mon 10/197:25 pm -
1 stop3h 25m
Deal found 9/1![Southwest logo]()
$334
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1912:40 pm -
2 stops10h 05m
Fri 10/237:15 am -
2 stops9h 40m
Deal found 9/1![Southwest logo]()
$357
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:20 am -
1 stop4h 25m
Wed 9/303:45 pm -
1 stop7h 59m
Deal found 8/31![United Airlines logo]()
$426
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:05 pm -
2 stops6h 55m
Wed 9/308:05 am -
2 stops6h 50m
Deal found 9/4![Southwest logo]()
$366
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:37 am -
2 stops13h 12m
Sun 9/137:20 pm -
1 stop4h 39m
Deal found 8/31![United Airlines logo]()
$495
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:20 pm -
2 stops7h 29m
Sun 9/137:20 pm -
1 stop4h 39m
Deal found 9/1![United Airlines logo]()
$495
Last-minute flights from Columbus to KnoxvilleDiscover last-minute flight deals from Columbus to Knoxville. Data last updated September 4, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to Knoxville. Data last updated September 4, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:50 pm -
2 stops20h 53m
Wed 9/3010:28 am -
1 stop10h 03m
Deal found 8/31![Multiple Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:50 am -
1 stop5h 15m
Wed 9/307:00 am -
2 stops7h 55m
Deal found 9/2![Southwest logo]()
$278
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:15 pm -
1 stop4h 40m
Wed 10/78:20 am -
2 stops11h 50m
Deal found 8/31![Southwest logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/49:16 pm -
1 stop13h 28m
Sun 10/117:58 pm -
2 stops46h 50m
Deal found 9/3![Multiple Airlines logo]()
$306
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:02 am -
1 stop4h 35m
Sat 10/2410:42 am -
1 stop6h 23m
Deal found 9/2![United Airlines logo]()
$273
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:55 am -
1 stop10h 15m
Sat 10/246:40 am -
2 stops5h 45m
Deal found 9/2![Southwest logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:44 pm -
2 stops25h 37m
Thu 10/229:11 pm -
1 stop21h 44m
Deal found 8/31![Multiple Airlines logo]()
$292
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am -
1 stop3h 34m
Fri 10/237:45 pm -
1 stop4h 59m
Deal found 9/1![Delta logo]()
$288
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:50 pm -
2 stops6h 55m
Fri 10/237:25 pm -
1 stop3h 25m
Deal found 9/1![Southwest logo]()
$308
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:35 pm -
2 stops6h 30m
Sat 10/318:25 am -
1 stop3h 40m
Deal found 9/3![Southwest logo]()
$293
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:50 am -
2 stops5h 30m
Sat 10/316:40 am -
2 stops10h 40m
Deal found 9/3![Southwest logo]()
$289
One-way flights from Columbus to KnoxvilleSearch for one-way flight options from Columbus to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 4, 2026.
Search for one-way flight options from Columbus to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:44 pm -
2 stops39h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Multiple Airlines logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:44 pm -
2 stops26h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$126
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:00 am -
1 stop3h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Delta logo]()
$137
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:50 pm -
2 stops6h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Southwest logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:50 pm -
2 stops23h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Multiple Airlines logo]()
$147
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:02 am -
1 stop4h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![United Airlines logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:50 pm -
3 stops41h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$165
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:35 pm -
2 stops6h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Southwest logo]()
$168
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:03 pm -
1 stop3h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![American Airlines logo]()
$174
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:05 am -
2 stops8h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![United Airlines logo]()
$177
Find flight deals from Columbus to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Columbus (CMH) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $273 (United Airlines) |
One-way from | $105 (Kiwi.com) |
Popular in | May |
Cheapest in | February |
Average price | $386 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 4, 2026.
Use the filters below to find and compare flights from Columbus Airport to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Tue 10/6
7:00 am-10:54 am
1 stop3h 54m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$137
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Tue 10/27
1:29 pm-10:05 am
1 stop20h 36m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$151
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Tue 10/6
6:02 am-10:37 am
1 stop4h 35m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$163
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Wed 10/14
2:35 pm-9:05 pm
2 stops6h 30m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$168
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Sun 11/1
7:27 pm-11:47 pm
1 stop4h 20m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$174
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Sun 10/4
6:02 am-10:37 am
1 stop4h 35m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$174
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Tue 10/13
6:05 am-2:42 pm
2 stops8h 37m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$177
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Sun 10/4
7:50 pm-10:20 pm
3 stops26h 30m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$183
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Tue 10/13
2:35 pm-9:05 pm
2 stops6h 30m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$199
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Wed 9/30
3:15 pm-7:55 pm
1 stop4h 40m
Knoxville McGhee Tyson
Wed 10/7
8:20 am-12:20 pm
1 stop4h 00m
$273
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Columbus to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbus to Knoxville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Columbus Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbus Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbus Airport-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Columbus Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbus Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Columbus to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Columbus with our price prediction graph.
CMH-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus Airport to Knoxville
What’s the top layover airport for flights from Columbus Airport to Knoxville?
Share of 1-stop round-trip flights from Columbus Airport to Knoxville chosen by Cheapflights users in the past 12 months, using the same layover each way.
Charlotte (CLT) – chosen by Cheapflights users on 50% of 1-stop itineraries from Columbus Airport to Knoxville on Cheapflights.
What’s the cheapest layover airport for flights from Columbus Airport to Knoxville?
Average round-trip fare for 1-stop flights from Columbus Airport to Knoxville, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Charlotte (CLT) is the most affordable 1-stop option, with an average round-trip price of $236.
What’s the fastest layover option from Columbus Airport to Knoxville?
Shortest average travel time for 1-stop one-way flights from Columbus Airport to Knoxville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Charlotte (CLT) have the shortest average one-way travel time for 1-stop routes: 4h 09m.
Which airport typically offers the quickest layover for flights from Columbus Airport to Knoxville?
Average layover duration for 1-stop one-way flights from Columbus Airport to Knoxville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Washington, D.C. (IAD) offer the fastest connection on this route, with an average layover time of 1h 05m.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 4, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Columbus Airport to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Overall
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Overall
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Overall
7.8
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Columbus to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
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Top 3 airlines flying from Columbus to Knoxville
Discover the top 3 airlines that operate flights from Columbus to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$235 | Average$313 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$238 | Average$303 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$278 | Average$506 | FlexibilityNo cancel fee | On-timeN/A |