$108+ Cheap flights from Columbus (CMH) to Knoxville (TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — TYS
Aug 9 — Aug 161
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Columbus to KnoxvilleExplore the most affordable flight options available from Columbus to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 10, 2026.
Explore the most affordable flight options available from Columbus to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 10, 2026.
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
CMH
- TYS
1 stop3h 36m
Delta
Mon 8/105:40 am
TYS
- CMH
1 stop5h 58m
Delta
Deal found 7/10![Delta logo]()
$221
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/112:05 pm
CMH
- TYS
2 stops6h 50m
Southwest
Thu 9/107:10 am
TYS
- CMH
1 stop5h 15m
Southwest
Deal found 7/8![Southwest logo]()
$228
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:30 am
CMH
- TYS
1 stop5h 55m
Southwest
Fri 9/41:00 pm
TYS
- CMH
1 stop8h 10m
Southwest
Deal found 7/7![Southwest logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:44 pm
CMH
- TYS
2 stops28h 16m
Multiple Airlines
Mon 8/37:20 pm
TYS
- CMH
1 stop14h 48m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:30 am
CMH
- TYS
1 stop5h 55m
Southwest
Thu 8/137:10 am
TYS
- CMH
2 stops9h 50m
Southwest
Deal found 7/9![Southwest logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:44 pm
CMH
- TYS
2 stops14h 52m
Multiple Airlines
Mon 8/106:29 pm
TYS
- CMH
1 stop15h 39m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$275
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:35 am
CMH
- TYS
1 stop3h 45m
Delta
Sun 8/95:40 am
TYS
- CMH
1 stop3h 17m
Delta
Deal found 7/10![Delta logo]()
$279
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:01 pm
CMH
- TYS
1 stop6h 11m
United Airlines
Wed 8/55:45 am
TYS
- CMH
1 stop4h 04m
United Airlines
Deal found 7/8![United Airlines logo]()
$291
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/32:59 pm
CMH
- TYS
1 stop3h 53m
Delta
Wed 8/125:40 am
TYS
- CMH
1 stop3h 17m
Delta
Deal found 7/10![Delta logo]()
$299
Best flights from Columbus to KnoxvilleDiscover carefully curated flight deals from Columbus to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 10, 2026.
Discover carefully curated flight deals from Columbus to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 10, 2026.
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:23 pm
CMH
- TYS
1 stop5h 29m
Delta
Thu 8/1310:28 am
TYS
- CMH
1 stop5h 38m
Delta
Deal found 7/10![Delta logo]()
$221
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/111:45 am
CMH
- TYS
2 stops8h 05m
Southwest
Thu 9/107:10 am
TYS
- CMH
2 stops9h 50m
Southwest
Deal found 7/8![Southwest logo]()
$233
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:00 am
CMH
- TYS
1 stop3h 36m
Delta
Thu 8/137:30 am
TYS
- CMH
1 stop4h 08m
Delta
Deal found 7/9![Delta logo]()
$221
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:30 am
CMH
- TYS
1 stop5h 55m
Southwest
Thu 8/137:10 am
TYS
- CMH
2 stops9h 50m
Southwest
Deal found 7/9![Southwest logo]()
$272
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:00 am
CMH
- TYS
1 stop3h 36m
Delta
Sun 8/97:41 pm
TYS
- CMH
1 stop5h 17m
Delta
Deal found 7/10![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:30 am
CMH
- TYS
1 stop11h 40m
Southwest
Thu 8/137:10 am
TYS
- CMH
2 stops9h 50m
Southwest
Deal found 7/9![Southwest logo]()
$311
This Delta deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:35 am
CMH
- TYS
1 stop3h 34m
Delta
Wed 9/97:33 am
TYS
- CMH
1 stop3h 49m
Delta
Deal found 7/5![Delta logo]()
$301
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:10 am
CMH
- TYS
1 stop5h 10m
Southwest
Mon 8/2412:40 pm
TYS
- CMH
2 stops10h 10m
Southwest
Deal found 7/7![Southwest logo]()
$314
This Delta deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:05 am
CMH
- TYS
1 stop6h 29m
Delta
Sun 9/67:15 am
TYS
- CMH
1 stop6h 12m
Delta
Deal found 7/5![Delta logo]()
$301
Last-minute flights from Columbus to KnoxvilleDiscover last-minute flight deals from Columbus to Knoxville. Data last updated July 10, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to Knoxville. Data last updated July 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:44 pm
CMH
- TYS
2 stops28h 16m
Multiple Airlines
Mon 8/37:20 pm
TYS
- CMH
1 stop14h 48m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/25:44 pm
CMH
- TYS
2 stops28h 16m
Multiple Airlines
Mon 8/1012:50 pm
TYS
- CMH
1 stop6h 15m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$304
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/32:59 pm
CMH
- TYS
1 stop3h 53m
Delta
Wed 8/125:40 am
TYS
- CMH
1 stop3h 17m
Delta
Deal found 7/10![Delta logo]()
$299
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:35 am
CMH
- TYS
1 stop3h 45m
Delta
Sun 8/95:40 am
TYS
- CMH
1 stop3h 17m
Delta
Deal found 7/10![Delta logo]()
$279
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:01 pm
CMH
- TYS
1 stop6h 11m
United Airlines
Wed 8/55:45 am
TYS
- CMH
1 stop4h 04m
United Airlines
Deal found 7/8![United Airlines logo]()
$291
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:16 pm
CMH
- TYS
1 stop6h 38m
Delta
Wed 8/127:15 am
TYS
- CMH
1 stop6h 10m
Delta
Deal found 7/10![Delta logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:44 pm
CMH
- TYS
2 stops14h 52m
Multiple Airlines
Mon 8/106:29 pm
TYS
- CMH
1 stop15h 39m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$275
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:30 am
CMH
- TYS
1 stop11h 40m
Southwest
Thu 8/137:10 am
TYS
- CMH
2 stops9h 50m
Southwest
Deal found 7/9![Southwest logo]()
$311
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:30 am
CMH
- TYS
1 stop5h 55m
Southwest
Thu 8/137:10 am
TYS
- CMH
2 stops9h 50m
Southwest
Deal found 7/9![Southwest logo]()
$272
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:30 am
CMH
- TYS
1 stop5h 55m
Southwest
Fri 9/41:00 pm
TYS
- CMH
1 stop8h 10m
Southwest
Deal found 7/7![Southwest logo]()
$251
One-way flights from Columbus to KnoxvilleSearch for one-way flight options from Columbus to Knoxville. Find affordable one-way fares based on user searches. Data last updated July 10, 2026.
Search for one-way flight options from Columbus to Knoxville. Find affordable one-way fares based on user searches. Data last updated July 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:44 pm
CMH
- TYS
2 stops26h 34m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$108
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:00 am
CMH
- TYS
1 stop3h 36m
Delta
Deal found 7/7![Delta logo]()
$111
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am
CMH
- TYS
1 stop4h 37m
United Airlines
Deal found 7/5![United Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:59 pm
CMH
- TYS
1 stop20h 37m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/59:54 am
CMH
- TYS
2 stops24h 10m
Multiple Airlines
Deal found 7/5![Multiple Airlines logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:44 pm
CMH
- TYS
2 stops28h 16m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$181
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:37 pm
CMH
- TYS
1 stop5h 07m
Delta
Deal found 7/6![Delta logo]()
$189
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2112:05 pm
CMH
- TYS
1 stop5h 50m
Delta
Deal found 7/6![Delta logo]()
$219
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:40 am
CMH
- TYS
2 stops6h 25m
Southwest
Deal found 7/6![Southwest logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:45 pm
CMH
- TYS
2 stops20h 25m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$227
Find flight deals from Columbus to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Columbus (CMH) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $221 (Delta) |
One-way from | $108 (Kiwi.com) |
Popular in | May |
Cheapest in | February |
Average price | $337 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 10, 2026.
Use the filters below to find and compare flights from Columbus Airport to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Tue 8/4
6:23 pm-11:52 pm
1 stop5h 29m
Knoxville McGhee Tyson
Thu 8/13
10:28 am-4:06 pm
1 stop5h 38m
$221
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Thu 8/6
6:00 am-9:36 am
1 stop3h 36m
Knoxville McGhee Tyson
Thu 8/13
7:30 am-11:38 am
1 stop4h 08m
$221
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Tue 9/1
11:45 am-7:50 pm
2 stops8h 05m
Knoxville McGhee Tyson
Thu 9/10
7:10 am-5:00 pm
2 stops9h 50m
$233
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Fri 8/7
7:30 am-1:25 pm
1 stop5h 55m
Knoxville McGhee Tyson
Thu 8/13
7:10 am-5:00 pm
2 stops9h 50m
$272
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Thu 8/6
6:00 am-9:36 am
1 stop3h 36m
Knoxville McGhee Tyson
Sun 8/9
7:41 pm-12:58 am
1 stop5h 17m
$279
Quickest round-trip
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Sun 9/6
6:35 am-10:09 am
1 stop3h 34m
Knoxville McGhee Tyson
Wed 9/9
7:33 am-11:22 am
1 stop3h 49m
$301
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Fri 9/4
7:05 am-1:34 pm
1 stop6h 29m
Knoxville McGhee Tyson
Sun 9/6
7:15 am-1:27 pm
1 stop6h 12m
$301
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Thu 8/6
5:30 am-5:10 pm
1 stop11h 40m
Knoxville McGhee Tyson
Thu 8/13
7:10 am-5:00 pm
2 stops9h 50m
$311
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Fri 8/21
7:10 am-12:20 pm
1 stop5h 10m
Knoxville McGhee Tyson
Mon 8/24
12:40 pm-10:50 pm
2 stops10h 10m
$314
Cheapest one-way
ColumbusKnoxville
CMH - TYS
CMHTYS
Columbus
Thu 8/6
5:44 pm-8:18 pm
2 stops26h 34m
$108
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Columbus to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbus to Knoxville in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Columbus Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbus Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbus Airport-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Columbus Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbus Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Columbus to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Columbus with our price prediction graph.
CMH-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus Airport to Knoxville
Prices
More
What’s the top layover airport for flights from Columbus Airport to Knoxville?
Share of 1-stop round-trip flights from Columbus Airport to Knoxville chosen by Cheapflights users in the past 12 months, using the same layover each way.
Charlotte (CLT) – chosen by Cheapflights users on 50% of 1-stop itineraries from Columbus Airport to Knoxville on Cheapflights.
What’s the cheapest layover airport for flights from Columbus Airport to Knoxville?
Average round-trip fare for 1-stop flights from Columbus Airport to Knoxville, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Charlotte (CLT) is the most affordable 1-stop option, with an average round-trip price of $236.
What’s the fastest layover option from Columbus Airport to Knoxville?
Shortest average travel time for 1-stop one-way flights from Columbus Airport to Knoxville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Charlotte (CLT) have the shortest average one-way travel time for 1-stop routes: 4h 09m.
Which airport typically offers the quickest layover for flights from Columbus Airport to Knoxville?
Average layover duration for 1-stop one-way flights from Columbus Airport to Knoxville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Washington, D.C. (IAD) offer the fastest connection on this route, with an average layover time of 1h 05m.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 10, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Columbus Airport to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Boarding
8.1
Crew
8.5
Entertainment
7.8
Overall
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Boarding
8.1
Crew
8.5
Entertainment
7.8
Overall
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Boarding
8.1
Crew
8.5
Entertainment
7.8
Overall
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Boarding
8.1
Crew
8.5
Entertainment
7.8
Overall
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Columbus to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
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Top 3 airlines flying from Columbus to Knoxville
Discover the top 3 airlines that operate flights from Columbus to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$223 | Average$467 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$235 | Average$462 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$236 | Average$324 | FlexibilityNo cancel fee | On-time71% |