$137+ Cheap flights from Columbus (CMH) to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/13. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — TYS
Oct 24 — Oct 311
Round-trip
1 adult, Economy
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Find cheap flights from Columbus to Knoxville with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbus to Knoxville
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Cheapest flights from Columbus to KnoxvilleExplore the most affordable flight options available from Columbus to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
Explore the most affordable flight options available from Columbus to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:16 pm -
1 stop6h 45m
Sat 10/311:55 pm -
1 stop4h 55m
Deal found 9/21![United Airlines logo]()
$273
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:00 am -
1 stop5h 27m
Fri 12/116:17 pm -
1 stop6h 16m
Deal found 9/21![Delta logo]()
$297
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:36 pm -
1 stop4h 23m
Mon 10/197:58 pm -
1 stop4h 23m
Deal found 9/21![American Airlines logo]()
$298
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:00 am -
1 stop3h 28m
Tue 12/17:10 am -
1 stop6h 21m
Deal found 9/20![Delta logo]()
$310
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:15 pm -
1 stop3h 55m
Tue 10/278:20 am -
2 stops9h 40m
Deal found 9/20![Southwest logo]()
$313
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:35 am -
2 stops11h 10m
Thu 10/227:25 pm -
1 stop3h 25m
Deal found 9/22![Southwest logo]()
$319
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:45 am -
2 stops12h 10m
Sat 10/316:40 am -
2 stops10h 40m
Deal found 9/21![Southwest logo]()
$330
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/43:45 pm -
1 stop5h 00m
Fri 12/118:10 am -
2 stops8h 35m
Deal found 9/21![Southwest logo]()
$333
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:20 am -
1 stop4h 25m
Fri 10/305:40 pm -
1 stop6h 04m
Deal found 9/23![United Airlines logo]()
$342
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:02 am -
1 stop4h 35m
Wed 10/219:45 am -
1 stop4h 23m
Deal found 9/22![United Airlines logo]()
$356
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:15 pm -
1 stop3h 44m
Sun 11/227:01 am -
1 stop5h 28m
Deal found 9/21![American Airlines logo]()
$367
Best flights from Columbus to KnoxvilleDiscover carefully curated flight deals from Columbus to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
Discover carefully curated flight deals from Columbus to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:15 pm -
1 stop3h 55m
Tue 10/278:20 am -
2 stops9h 40m
Deal found 9/20![Southwest logo]()
$313
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:15 pm -
1 stop3h 44m
Mon 11/238:04 pm -
1 stop3h 53m
Deal found 9/19![American Airlines logo]()
$330
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:20 am -
1 stop4h 25m
Fri 10/305:40 pm -
1 stop6h 04m
Deal found 9/23![United Airlines logo]()
$342
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop4h 54m
Mon 10/127:45 pm -
1 stop4h 59m
Deal found 9/20![Delta logo]()
$370
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:35 am -
2 stops11h 10m
Thu 10/227:25 pm -
1 stop3h 25m
Deal found 9/22![Southwest logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:02 am -
1 stop4h 35m
Thu 10/229:45 am -
1 stop4h 23m
Deal found 9/22![United Airlines logo]()
$356
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:20 am -
1 stop4h 25m
Sun 10/255:45 am -
1 stop4h 10m
Deal found 9/23![United Airlines logo]()
$415
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:00 am -
1 stop3h 54m
Sun 10/115:18 pm -
1 stop3h 40m
Deal found 9/21![Delta logo]()
$467
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:02 am -
1 stop4h 35m
Sat 10/101:55 pm -
1 stop6h 57m
Deal found 9/21![United Airlines logo]()
$467
Last-minute flights from Columbus to KnoxvilleDiscover last-minute flight deals from Columbus to Knoxville. Data last updated September 24, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to Knoxville. Data last updated September 24, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop4h 54m
Mon 10/127:45 pm -
1 stop4h 59m
Deal found 9/21![Delta logo]()
$370
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:36 pm -
1 stop4h 23m
Mon 10/197:58 pm -
1 stop4h 23m
Deal found 9/21![American Airlines logo]()
$298
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:02 am -
1 stop4h 35m
Wed 10/219:45 am -
1 stop4h 23m
Deal found 9/22![United Airlines logo]()
$356
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:44 pm -
2 stops25h 55m
Thu 10/227:00 am -
1 stop10h 17m
Deal found 9/22![Multiple Airlines logo]()
$411
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:35 am -
2 stops11h 10m
Thu 10/227:25 pm -
1 stop3h 25m
Deal found 9/22![Southwest logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:45 pm -
2 stops7h 14m
Thu 10/226:00 am -
2 stops8h 08m
Deal found 9/22![United Airlines logo]()
$408
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:15 pm -
1 stop3h 55m
Tue 10/278:20 am -
2 stops9h 40m
Deal found 9/20![Southwest logo]()
$313
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:20 am -
1 stop4h 25m
Fri 10/305:40 pm -
1 stop6h 04m
Deal found 9/23![United Airlines logo]()
$342
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:16 pm -
1 stop6h 45m
Sat 10/311:55 pm -
1 stop4h 55m
Deal found 9/21![United Airlines logo]()
$273
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:45 am -
2 stops12h 10m
Sat 10/316:40 am -
2 stops10h 40m
Deal found 9/21![Southwest logo]()
$330
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:45 am -
2 stops12h 10m
Mon 10/267:25 pm -
1 stop3h 25m
Deal found 9/21![Southwest logo]()
$398
One-way flights from Columbus to KnoxvilleSearch for one-way flight options from Columbus to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
Search for one-way flight options from Columbus to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
1 stop3h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Delta logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:27 pm -
3 stops41h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Multiple Airlines logo]()
$152
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:25 am -
1 stop3h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Delta logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:44 pm -
2 stops23h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Multiple Airlines logo]()
$180
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:15 am -
2 stops11h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![United Airlines logo]()
$187
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:20 am -
1 stop4h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![United Airlines logo]()
$192
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:15 pm -
1 stop3h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![American Airlines logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:35 pm -
1 stop19h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$206
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:00 am -
1 stop3h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Delta logo]()
$234
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
1 stop4h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![American Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:26 pm -
2 stops28h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$252
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop4h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Delta logo]()
$270
Find flight deals from Columbus to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Columbus (CMH) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $273 (United Airlines) |
One-way from | $137 (Delta) |
Popular in | May |
Cheapest in | February |
Average price | $576 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
Use the filters below to find and compare flights from Columbus Airport to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Sat 10/24
6:00 am-10:25 am
1 stop4h 25m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$137
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Sun 11/1
6:25 am-10:20 am
1 stop3h 55m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$174
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Sat 10/24
9:15 am-8:19 pm
2 stops11h 04m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$187
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Fri 10/23
5:20 am-9:45 am
1 stop4h 25m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$192
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Fri 10/23
7:35 pm-10:05 am
2 stops14h 30m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$194
Quickest round-trip
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Tue 10/6
7:00 am-10:54 am
1 stop3h 54m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$234
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Sat 10/10
4:19 pm-8:49 pm
1 stop4h 30m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$234
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Thu 10/8
6:00 am-10:33 am
1 stop4h 33m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$244
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Fri 10/9
6:00 am-10:54 am
1 stop4h 54m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$270
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Tue 10/20
4:15 pm-8:10 pm
1 stop3h 55m
Knoxville McGhee Tyson
Tue 10/27
8:20 am-6:00 pm
2 stops9h 40m
$313
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Columbus to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbus to Knoxville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Columbus Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbus Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbus Airport-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Columbus Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbus Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Columbus to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Columbus with our price prediction graph.
CMH-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus Airport to Knoxville
Prices
More
What’s the top layover airport for flights from Columbus Airport to Knoxville?
Share of 1-stop round-trip flights from Columbus Airport to Knoxville chosen by Cheapflights users in the past 12 months, using the same layover each way.
Charlotte (CLT) – chosen by Cheapflights users on 50% of 1-stop itineraries from Columbus Airport to Knoxville on Cheapflights.
What’s the cheapest layover airport for flights from Columbus Airport to Knoxville?
Average round-trip fare for 1-stop flights from Columbus Airport to Knoxville, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Charlotte (CLT) is the most affordable 1-stop option, with an average round-trip price of $236.
What’s the fastest layover option from Columbus Airport to Knoxville?
Shortest average travel time for 1-stop one-way flights from Columbus Airport to Knoxville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Charlotte (CLT) have the shortest average one-way travel time for 1-stop routes: 4h 09m.
Which airport typically offers the quickest layover for flights from Columbus Airport to Knoxville?
Average layover duration for 1-stop one-way flights from Columbus Airport to Knoxville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Washington, D.C. (IAD) offer the fastest connection on this route, with an average layover time of 1h 05m.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 24, 2026.
Get a feel of what it's like to fly with American Airlines from Columbus Airport to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Entertainment
6.8
Boarding
7.4
Food
6.4
Overall
7.0
Comfort
7.2
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Crew
7.9
Entertainment
6.8
Boarding
7.4
Food
6.4
Overall
7.0
Comfort
7.2
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Columbus to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
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Bryson City
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Top airline flying from Columbus to Knoxville
Discover the top airline that operate flights from Columbus to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$238 | Average$309 | FlexibilityNo cancel fee | On-time71% |