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Knoxville

$140+ Cheap flights from Columbus (CMH) to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/2. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — TYS
Apr 15 — Apr 221
Wed 4/15
Wed 4/22
1 adult, Economy
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Cheap flight deals from Columbus to Knoxville

Cheapest flights from Columbus to Knoxville
Explore the most affordable flight options available from Columbus to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 16, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:45 am
CMH
-
TYS
1 stop16h 20m
Multiple Airlines
Thu 4/164:28 pm
TYS
-
CMH
1 stop27h 05m
Multiple Airlines
Deal found 3/12$273
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:45 am
CMH
-
TYS
1 stop8h 25m
Multiple Airlines
Wed 3/258:30 am
TYS
-
CMH
1 stop14h 49m
Multiple Airlines
Deal found 3/12$284
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:05 pm
CMH
-
TYS
1 stop5h 05m
Southwest
Tue 4/217:05 am
TYS
-
CMH
1 stop5h 25m
Southwest
Deal found 3/15$291
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2611:03 am
CMH
-
TYS
1 stop6h 09m
United Airlines
Fri 5/296:30 am
TYS
-
CMH
1 stop6h 47m
United Airlines
Deal found 3/12$300
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/118:00 pm
CMH
-
TYS
1 stop3h 55m
American Airlines
Sat 4/187:00 am
TYS
-
CMH
1 stop5h 35m
American Airlines
Deal found 3/13$301
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2410:40 am
CMH
-
TYS
1 stop24h 00m
Multiple Airlines
Sat 3/289:36 pm
TYS
-
CMH
2 stops16h 20m
Multiple Airlines
Deal found 3/12$304
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:05 am
CMH
-
TYS
1 stop6h 40m
Multiple Airlines
Thu 4/304:28 pm
TYS
-
CMH
1 stop26h 45m
Multiple Airlines
Deal found 3/12$305
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:15 pm
CMH
-
TYS
2 stops7h 05m
Southwest
Thu 4/168:05 am
TYS
-
CMH
2 stops10h 05m
Southwest
Deal found 3/12$311
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:05 am
CMH
-
TYS
2 stops12h 25m
Southwest
Sat 4/185:40 pm
TYS
-
CMH
1 stop3h 15m
Southwest
Deal found 3/13$312
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:50 am
CMH
-
TYS
2 stops10h 50m
Southwest
Fri 5/296:35 am
TYS
-
CMH
1 stop5h 25m
Southwest
Deal found 3/12$315

Find flight deals from Columbus to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Columbus (CMH) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 16, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$273
(Kiwi.com)

One-way from

$140
(Kiwi.com)

Popular in

January

Cheapest in

July

Average price

$333
Provider with most accurate pricing for Columbus-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Columbus-Knoxville McGhee Tyson flights.
Search Deals
From Columbus to Knoxville McGhee Tyson
Search Deals
One-way flight from Columbus to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($102 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
Use the filters below to find and compare flights from Columbus Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Thu 4/9

5:45 am-10:05 pm

1 stop16h 20m

Knoxville McGhee Tyson

Thu 4/16

9:32 pm-5:40 pm

2 stops20h 08m

$288

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Thu 4/9

1:15 pm-8:20 pm

2 stops7h 05m

Knoxville McGhee Tyson

Thu 4/16

8:05 am-6:10 pm

2 stops10h 05m

$311

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Tue 5/26

8:50 am-7:40 pm

2 stops10h 50m

Knoxville McGhee Tyson

Fri 5/29

6:35 am-6:10 pm

2 stops11h 35m

$326

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Sat 4/4

10:36 am-3:09 pm

1 stop4h 33m

Knoxville McGhee Tyson

Wed 4/8

10:49 am-6:43 pm

2 stops7h 54m

$342

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Fri 5/8

7:45 am-6:10 pm

1 stop10h 25m

Knoxville McGhee Tyson

Sun 5/10

6:40 am-12:45 pm

2 stops6h 05m

$348
Quickest round-trip

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Fri 7/31

6:00 am-9:11 am

1 stop3h 11m

Knoxville McGhee Tyson

Sun 8/2

7:30 am-1:27 pm

1 stop5h 57m

$357

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Fri 4/3

4:10 pm-10:34 pm

1 stop6h 24m

Knoxville McGhee Tyson

Sun 4/5

7:00 am-1:12 pm

1 stop6h 12m

$377

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Sat 4/18

6:05 am-6:30 pm

2 stops12h 25m

Knoxville McGhee Tyson

Mon 4/20

12:15 pm-10:05 pm

2 stops9h 50m

$380

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Thu 4/16

9:50 am-3:38 pm

1 stop5h 48m

Knoxville McGhee Tyson

Sun 4/19

7:00 am-12:30 pm

1 stop5h 30m

$387
Cheapest one-way

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Sun 7/12

6:00 am-10:42 am

1 stop4h 42m

$169

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/11

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Compare providers for flights from Columbus to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbus to Knoxville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Columbus Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbus Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbus Airport-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Columbus Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbus Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Columbus to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to Knoxville

What is the cheapest month to book a flight from Columbus Airport to Knoxville?

Currently, June is the cheapest month in which you can book a flight from Columbus Airport to Knoxville (average of $200). Flying from Columbus Airport to Knoxville in March is currently the most expensive (average of $262). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 16, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Columbus Airport to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,288 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,288 reviews
Delta
7.9
Good
8,288 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,431 reviews
Delta
7.9
Good
8,288 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,468 reviews
Delta
7.9
Good
8,288 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Columbus?

    Most people fly into Knoxville McGhee Tyson (TYS) if they book a flight to Knoxville from Columbus. On average, McGhee Tyson has 0 inbound flights from Columbus per day from 3 airlines. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Columbus Airport to Knoxville?

    For as low as $342, Southwest can have you in Knoxville from Columbus Airport in 4h 33m. There are 296 mi between Columbus Airport and Knoxville. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Columbus Airport to Knoxville round-trip?

    Currently priced at $218, American Airlines will fly you from Columbus Airport to Knoxville and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and United Airlines - these airlines can fly you to your destination from $218 and $235, respectively. These flights start at 36% lower than the current average price 3 months from now.

  • Can I find deals for flights from Columbus to Knoxville that include hotel bookings?

    Yes. In addition to deals on Columbus to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Knoxville.

  • Can I find deals for business class flights from Columbus to Knoxville?

    Yes. Cheapflights offers flight deals from Columbus to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus Airport to Knoxville?

    Currently, June is the cheapest month in which you can book a flight from Columbus Airport to Knoxville (average of $200). Flying from Columbus Airport to Knoxville in March is currently the most expensive (average of $262). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

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Alternative routes for Columbus to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Columbus to Nashville flights
Columbus to Memphis flights
Columbus to Chattanooga flights

Top 3 airlines flying from Columbus to Knoxville

Discover the top 3 airlines that operate flights from Columbus to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$218Average$293FlexibilityNo cancel feeOn-time71%
DeltaCheapest$218Average$467FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$235Average$462FlexibilityNo cancel feeOn-time69%

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