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Knoxville

$103+ Cheap flights from Columbus (CMH) to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — TYS
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
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Find flight deals from Columbus to Knoxville

Cheapest flights from Columbus to Knoxville
Explore the most affordable flight options available from Columbus to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/46:00 amCMH - TYS
1 stop3h 50mAmerican Airlines
Tue 11/116:06 amTYS - CMH
1 stop5h 38mAmerican Airlines
Deal found 10/14$239
This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/129:42 amCMH - TYS
1 stop12h 32mMultiple Airlines
Thu 11/139:54 amTYS - CMH
1 stop13h 16mMultiple Airlines
Deal found 10/15$250
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/163:54 pmCMH - TYS
1 stop6h 15mAmerican Airlines
Sat 10/1810:43 amTYS - CMH
1 stop4h 43mAmerican Airlines
Deal found 10/15$279
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2012:33 pmCMH - TYS
1 stop6h 29mDelta
Sun 11/237:39 amTYS - CMH
1 stop5h 44mDelta
Deal found 10/15$299
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:05 amCMH - TYS
1 stop3h 15mDelta
Sat 11/15:16 pmTYS - CMH
1 stop3h 21mDelta
Deal found 10/14$304
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:00 amCMH - TYS
1 stop4h 05mUnited Airlines
Mon 11/249:50 amTYS - CMH
1 stop4h 18mUnited Airlines
Deal found 10/16$311
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/43:05 pmCMH - TYS
2 stops7h 50mUnited Airlines
Tue 11/118:26 amTYS - CMH
1 stop4h 55mUnited Airlines
Deal found 10/14$316
This Mytrip deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/218:30 amCMH - TYS
1 stop13h 00mMultiple Airlines
Mon 11/249:29 pmTYS - CMH
2 stops16h 44mMultiple Airlines
Deal found 10/16$325
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3112:28 pmCMH - TYS
1 stop10h 38mMultiple Airlines
Sun 11/27:00 amTYS - CMH
2 stops25h 47mMultiple Airlines
Deal found 10/16$335
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:12 amCMH - TYS
1 stop4h 40mAmerican Airlines
Mon 11/246:05 amTYS - CMH
1 stop6h 03mAmerican Airlines
Deal found 10/15$338
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:21 pmCMH - TYS
2 stops18h 40mMultiple Airlines
Tue 11/411:23 amTYS - CMH
1 stop11h 47mMultiple Airlines
Deal found 10/16$339

Cheap flight deals from Columbus to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Columbus (CMH) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$239
(Delta)

One-way from

$103
(Kiwi.com)

Popular in

November

Cheapest in

December

Average price

$298
Provider with most accurate pricing for Columbus-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Columbus-Knoxville McGhee Tyson flights.
Search Deals
From Columbus to Knoxville McGhee Tyson
Search Deals
One-way flight from Columbus to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 0% potential increase in price ($1 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Columbus Airport to Knoxville that are best for you.

Fly from

Columbus

Fly to

Knoxville

Route

Depart

Return

Price

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Sat 2/21

8:10 am-11:47 am

1 stop3h 37m

Knoxville McGhee Tyson

Wed 2/25

7:30 am-1:30 pm

1 stop6h 00m

$239

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Tue 11/4

6:00 am-9:50 am

1 stop3h 50m

Knoxville McGhee Tyson

Tue 11/11

6:06 am-11:44 am

1 stop5h 38m

$239

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Wed 11/12

9:42 am-10:14 pm

1 stop12h 32m

Knoxville McGhee Tyson

Thu 11/13

9:54 am-11:10 pm

1 stop13h 16m

$250

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Thu 11/20

12:33 pm-7:02 pm

1 stop6h 29m

Knoxville McGhee Tyson

Sun 11/23

7:39 am-1:23 pm

1 stop5h 44m

$299

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Thu 10/30

6:05 am-9:20 am

1 stop3h 15m

Knoxville McGhee Tyson

Sat 11/1

5:16 pm-8:37 pm

1 stop3h 21m

$304

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Fri 11/21

6:00 am-10:05 am

1 stop4h 05m

Knoxville McGhee Tyson

Mon 11/24

9:50 am-2:08 pm

1 stop4h 18m

$311

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Fri 11/21

8:30 am-9:30 pm

1 stop13h 00m

Knoxville McGhee Tyson

Mon 11/24

9:29 pm-2:13 pm

2 stops16h 44m

$325

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Fri 10/31

12:28 pm-11:06 pm

1 stop10h 38m

Knoxville McGhee Tyson

Sun 11/2

7:00 am-8:47 am

2 stops25h 47m

$335

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Fri 10/31

6:21 pm-1:01 pm

2 stops18h 40m

Knoxville McGhee Tyson

Tue 11/4

11:23 am-11:10 pm

1 stop11h 47m

$339

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Fri 10/31

3:51 pm-10:09 pm

1 stop6h 18m

Knoxville McGhee Tyson

Tue 11/4

6:06 am-11:44 am

1 stop5h 38m

$343

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/15

Showing 1-10 of 17 results
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Compare providers for flights from Columbus to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbus to Knoxville in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Columbus Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbus Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbus Airport-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Columbus Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbus Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Columbus to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to Knoxville

What is the cheapest month to book a flight from Columbus Airport to Knoxville?

Currently, April is the cheapest month in which you can book a flight from Columbus Airport to Knoxville (average of $193). Flying from Columbus Airport to Knoxville in March is currently the most expensive (average of $236). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to TYS?

Find hourly flight availability from Columbus to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 16, 2025.

One of the essential ways to save on airfare from Columbus Airport to Knoxville is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 33% on airfare.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated October 16, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Columbus Airport to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,984 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
8.0
Very good
7,984 reviews
Delta
8.0
Very good
7,984 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,982 reviews
Delta
8.0
Very good
7,984 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,043 reviews
Delta
8.0
Very good
7,984 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Columbus?

    Most people fly into Knoxville McGhee Tyson (TYS) if they book a flight to Knoxville from Columbus. On average, McGhee Tyson has 0 inbound flights from Columbus per day from 3 airlines. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Columbus Airport to Knoxville?

    For as low as $239, Delta can have you in Knoxville from Columbus Airport in 3h 37m. There are 296 mi between Columbus Airport and Knoxville. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Columbus Airport to Knoxville round-trip?

    Currently priced at $218, American Airlines will fly you from Columbus Airport to Knoxville and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and United Airlines - these airlines can fly you to your destination from $218 and $235, respectively. These flights start at 27% lower than the current average price 3 months from now.

  • Can I find deals for flights from Columbus to Knoxville that include hotel bookings?

    Yes. In addition to deals on Columbus to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Knoxville.

  • Can I find deals for business class flights from Columbus to Knoxville?

    Yes. Cheapflights offers flight deals from Columbus to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus Airport to Knoxville?

    Currently, April is the cheapest month in which you can book a flight from Columbus Airport to Knoxville (average of $193). Flying from Columbus Airport to Knoxville in March is currently the most expensive (average of $236). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Alternative routes for Columbus to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Columbus to Nashville flights
Columbus to Memphis flights
Columbus to Blountville flights
Columbus to Chattanooga flights

Top 3 airlines flying from Columbus to Knoxville

Discover the top 3 airlines that operate flights from Columbus to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$218Average$293FlexibilityNo cancel feeOn-time71%
DeltaCheapest$218Average$398FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$235Average$422FlexibilityNo cancel feeOn-time69%

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