
Discover tips and strategies to find the most affordable flight options for your journey from Columbus (CMH) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $195 (Kiwi.com) |
One-way from | $137 (Delta) |
Popular in | September |
Cheapest in | February |
Average price | $556 |
Fly from
Fly to
Route
Depart
Return
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Thu 1/14
8:07 am-2:48 pm
1 stop6h 41m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Thu 11/12
1:29 pm-10:37 pm
1 stop9h 08m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Thu 1/14
12:20 pm-4:54 pm
1 stop4h 34m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Wed 11/11
7:22 pm-12:27 pm
3 stops41h 05m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Fri 11/20
1:06 pm-6:16 pm
1 stop5h 10m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Fri 11/6
6:32 pm-9:00 pm
2 stops26h 28m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Fri 11/27
12:55 pm-9:45 pm
1 stop8h 50m
Knoxville McGhee Tyson
Tue 12/1
7:55 am-9:05 pm
2 stops13h 10m
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Sat 1/30
2:15 pm-9:05 pm
1 stop6h 50m
Knoxville McGhee Tyson
Wed 2/3
10:45 am-4:47 pm
1 stop6h 02m
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Fri 11/13
3:04 pm-7:32 pm
1 stop4h 28m
Knoxville McGhee Tyson
Fri 11/20
4:00 pm-10:23 pm
1 stop6h 23m
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Mon 11/30
10:28 am-5:51 pm
1 stop7h 23m
Knoxville McGhee Tyson
Sun 12/6
11:00 am-12:20 pm
2 stops25h 20m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
Everything you need to know about your flight from Columbus Airport to Knoxville
Entertainment
Comfort
Boarding
Overall
Crew
Food
Reviews
Asha,Sep 2026
LGA - IAH
Entertainment
Comfort
Boarding
Overall
Crew
Food
Reviews
Asha,Sep 2026
LGA - IAH
Entertainment
Comfort
Boarding
Overall
Crew
Food
Reviews
Asha,Sep 2026
LGA - IAH
Find useful and relevant information for your journey from Columbus to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$386 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$272 | Average$313 | FlexibilityNo cancel fee | On-time69% |