$169+ Cheap flights from Columbus (CMH) to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — TYS
Nov 19 — Nov 261
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbus to Knoxville
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Cheapest flights from Columbus to KnoxvilleExplore the most affordable flight options available from Columbus to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
Explore the most affordable flight options available from Columbus to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/71:24 pm -
1 stop23h 43m
Mon 12/141:58 pm -
2 stops22h 00m
Deal found 10/20![Multiple Airlines logo]()
$225
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:05 pm -
1 stop4h 52m
Mon 12/145:10 pm -
1 stop6h 58m
Deal found 10/20![Delta logo]()
$239
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:45 pm -
1 stop5h 05m
Sun 12/67:25 pm -
1 stop3h 15m
Deal found 10/19![Southwest logo]()
$243
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/98:40 am -
2 stops11h 10m
Mon 12/145:15 pm -
1 stop3h 50m
Deal found 10/20![Southwest logo]()
$244
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1011:50 am -
1 stop8h 00m
Mon 12/145:15 pm -
1 stop3h 50m
Deal found 10/20![Southwest logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/111:24 pm -
1 stop21h 13m
Tue 12/151:57 pm -
1 stop22h 23m
Deal found 10/20![Multiple Airlines logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:32 pm -
2 stops14h 55m
Tue 12/151:57 pm -
1 stop22h 23m
Deal found 10/20![Multiple Airlines logo]()
$284
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/75:47 pm -
1 stop6h 10m
Sun 12/137:26 pm -
1 stop5h 07m
Deal found 10/20![Delta logo]()
$287
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/101:10 pm -
1 stop4h 20m
Mon 12/145:10 pm -
1 stop3h 53m
Deal found 10/20![Delta logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:35 pm -
2 stops17h 32m
Tue 12/151:57 pm -
1 stop22h 23m
Deal found 10/20![Multiple Airlines logo]()
$311
Best flights from Columbus to KnoxvilleDiscover carefully curated flight deals from Columbus to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
Discover carefully curated flight deals from Columbus to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:30 am -
1 stop3h 57m
Tue 12/152:36 pm -
1 stop3h 33m
Deal found 10/20![Delta logo]()
$239
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:20 am -
2 stops6h 00m
Sun 12/67:25 pm -
1 stop3h 15m
Deal found 10/19![Southwest logo]()
$249
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/29:04 am -
1 stop4h 09m
Fri 11/66:45 am -
1 stop6h 25m
Deal found 10/18![United Airlines logo]()
$487
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/101:10 pm -
1 stop4h 20m
Mon 12/145:10 pm -
1 stop3h 53m
Deal found 10/20![Delta logo]()
$303
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:05 pm -
1 stop4h 52m
Mon 12/146:17 pm -
1 stop6h 16m
Deal found 10/20![Delta logo]()
$303
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:05 pm -
1 stop4h 52m
Wed 12/165:10 pm -
1 stop3h 53m
Deal found 10/20![Delta logo]()
$303
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/101:10 pm -
1 stop4h 20m
Tue 12/1512:32 pm -
1 stop3h 58m
Deal found 10/20![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:55 am -
2 stops13h 40m
Fri 11/208:10 am -
2 stops8h 35m
Deal found 10/16![Southwest logo]()
$415
This Southwest deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
1 stop6h 20m
Fri 11/277:25 pm -
1 stop3h 10m
Deal found 10/16![Southwest logo]()
$442
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:05 am -
1 stop4h 23m
Fri 11/208:35 am -
1 stop3h 26m
Deal found 10/16![Delta logo]()
$342
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:05 am -
2 stops10h 45m
Sun 11/157:25 pm -
1 stop3h 10m
Deal found 10/18![Southwest logo]()
$443
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop4h 54m
Tue 11/37:26 am -
1 stop6h 05m
Deal found 10/15![Delta logo]()
$487
Last-minute flights from Columbus to KnoxvilleDiscover last-minute flight deals from Columbus to Knoxville. Data last updated October 20, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to Knoxville. Data last updated October 20, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:29 pm -
1 stop8h 55m
Fri 10/307:00 am -
2 stops11h 55m
Deal found 10/16![Multiple Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop4h 54m
Tue 11/37:26 am -
1 stop6h 05m
Deal found 10/15![Delta logo]()
$487
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:35 pm -
2 stops10h 10m
Tue 11/35:15 pm -
1 stop3h 45m
Deal found 10/15![Southwest logo]()
$492
This Southwest deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:45 am -
1 stop8h 15m
Thu 11/57:05 am -
2 stops12h 40m
Deal found 10/17![Southwest logo]()
$498
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:05 am -
1 stop4h 23m
Fri 11/208:35 am -
1 stop3h 26m
Deal found 10/16![Delta logo]()
$342
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:35 pm -
2 stops14h 30m
Fri 11/209:13 pm -
1 stop19h 27m
Deal found 10/16![Multiple Airlines logo]()
$358
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:30 am -
1 stop5h 40m
Fri 11/208:10 am -
2 stops8h 35m
Deal found 10/15![Southwest logo]()
$407
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:05 am -
2 stops10h 45m
Sun 11/157:25 pm -
1 stop3h 10m
Deal found 10/18![Southwest logo]()
$443
This Southwest deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
1 stop6h 20m
Fri 11/277:25 pm -
1 stop3h 10m
Deal found 10/16![Southwest logo]()
$442
One-way flights from Columbus to KnoxvilleSearch for one-way flight options from Columbus to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 20, 2026.
Search for one-way flight options from Columbus to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:22 pm -
2 stops14h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Multiple Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/11:29 pm -
1 stop29h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Multiple Airlines logo]()
$234
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:03 pm -
1 stop3h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![American Airlines logo]()
$244
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:00 am -
1 stop3h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Delta logo]()
$263
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:56 pm -
1 stop4h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![United Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:15 pm -
1 stop3h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![American Airlines logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:32 pm -
2 stops37h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$324
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:15 am -
1 stop4h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![United Airlines logo]()
$339
Find flight deals from Columbus to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Columbus (CMH) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $225 (Kiwi.com) |
One-way from | $169 (Kiwi.com) |
Popular in | September |
Cheapest in | February |
Average price | $442 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 20, 2026.
Use the filters below to find and compare flights from Columbus Airport to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Sat 10/31
7:22 pm-9:43 am
2 stops14h 21m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$169
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Sun 11/1
1:29 pm-7:24 pm
1 stop29h 55m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$234
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Tue 12/8
6:30 am-10:27 am
1 stop3h 57m
Knoxville McGhee Tyson
Tue 12/15
2:36 pm-6:09 pm
1 stop3h 33m
$239
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Thu 12/3
6:20 am-12:20 pm
2 stops6h 00m
Knoxville McGhee Tyson
Sun 12/6
7:25 pm-10:40 pm
1 stop3h 15m
$249
Quickest round-trip
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Fri 11/20
6:00 am-9:55 am
1 stop3h 55m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$263
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Fri 11/20
7:56 pm-11:59 pm
1 stop4h 03m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$280
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Sun 11/1
6:10 am-4:59 pm
2 stops10h 49m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$294
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Thu 12/10
1:10 pm-5:30 pm
1 stop4h 20m
Knoxville McGhee Tyson
Mon 12/14
5:10 pm-9:03 pm
1 stop3h 53m
$303
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Fri 12/11
7:05 pm-11:57 pm
1 stop4h 52m
Knoxville McGhee Tyson
Mon 12/14
6:17 pm-12:33 am
1 stop6h 16m
$303
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Thu 12/10
7:05 pm-11:57 pm
1 stop4h 52m
Knoxville McGhee Tyson
Wed 12/16
5:10 pm-9:03 pm
1 stop3h 53m
$303
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Columbus to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbus to Knoxville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Columbus Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbus Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbus Airport-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Columbus Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbus Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Columbus to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Columbus with our price prediction graph.
CMH-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus Airport to Knoxville
What’s the top layover airport for flights from Columbus Airport to Knoxville?
Share of 1-stop round-trip flights from Columbus Airport to Knoxville chosen by Cheapflights users in the past 12 months, using the same layover each way.
Charlotte (CLT) – chosen by Cheapflights users on 50% of 1-stop itineraries from Columbus Airport to Knoxville on Cheapflights.
What’s the cheapest layover airport for flights from Columbus Airport to Knoxville?
Average round-trip fare for 1-stop flights from Columbus Airport to Knoxville, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Charlotte (CLT) is the most affordable 1-stop option, with an average round-trip price of $236.
What’s the fastest layover option from Columbus Airport to Knoxville?
Shortest average travel time for 1-stop one-way flights from Columbus Airport to Knoxville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Charlotte (CLT) have the shortest average one-way travel time for 1-stop routes: 4h 09m.
Which airport typically offers the quickest layover for flights from Columbus Airport to Knoxville?
Average layover duration for 1-stop one-way flights from Columbus Airport to Knoxville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Washington, D.C. (IAD) offer the fastest connection on this route, with an average layover time of 1h 05m.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated October 20, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Columbus Airport to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Food
6.7
Comfort
7.3
Boarding
7.7
Entertainment
7.1
Overall
7.3
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Crew
8.1
Food
6.7
Comfort
7.3
Boarding
7.7
Entertainment
7.1
Overall
7.3
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Crew
8.1
Food
6.7
Comfort
7.3
Boarding
7.7
Entertainment
7.1
Overall
7.3
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Columbus to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Newport
Bryson City
Murphy
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 20, 2026.
Columbus and Knoxville flights
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Top 2 airlines flying from Columbus to Knoxville
Discover the top 2 airlines that operate flights from Columbus to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$386 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$272 | Average$313 | FlexibilityNo cancel fee | On-time69% |