$132+ Cheap flights from Columbus (CMH) to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — TYS
Oct 31 — Nov 71
Round-trip
1 adult, Economy
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Find cheap flights from Columbus to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbus to Knoxville
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Best
Last-minute
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Cheapest flights from Columbus to KnoxvilleExplore the most affordable flight options available from Columbus to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 1, 2026.
Explore the most affordable flight options available from Columbus to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 1, 2026.
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/911:31 am -
1 stop4h 58m
Thu 11/127:52 am -
1 stop6h 24m
Deal found 9/30![American Airlines logo]()
$273
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:00 am -
1 stop5h 04m
Fri 1/17:35 pm -
1 stop4h 09m
Deal found 9/28![United Airlines logo]()
$285
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:45 am -
2 stops11h 50m
Thu 11/127:25 pm -
1 stop3h 10m
Deal found 9/30![Southwest logo]()
$331
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am -
1 stop4h 25m
Thu 10/227:58 pm -
1 stop4h 23m
Deal found 9/28![American Airlines logo]()
$356
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:15 am -
1 stop4h 38m
Mon 11/211:20 am -
1 stop7h 33m
Deal found 9/28![United Airlines logo]()
$363
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:04 am -
1 stop5h 00m
Mon 11/308:04 pm -
1 stop3h 53m
Deal found 9/28![American Airlines logo]()
$382
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3012:10 pm -
2 stops9h 30m
Fri 1/17:55 am -
1 stop10h 15m
Deal found 9/28![Southwest logo]()
$398
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:12 pm -
1 stop5h 06m
Tue 10/206:55 pm -
1 stop4h 29m
Deal found 9/26![American Airlines logo]()
$436
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:35 pm -
1 stop9h 46m
Mon 10/197:00 am -
2 stops35h 48m
Deal found 9/30![Multiple Airlines logo]()
$445
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:00 pm -
1 stop3h 41m
Sat 11/286:43 am -
1 stop4h 55m
Deal found 9/29![American Airlines logo]()
$452
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am -
1 stop3h 34m
Thu 10/157:26 am -
1 stop3h 49m
Deal found 9/28![Delta logo]()
$467
Best flights from Columbus to KnoxvilleDiscover carefully curated flight deals from Columbus to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 1, 2026.
Discover carefully curated flight deals from Columbus to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 1, 2026.
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/302:45 pm -
1 stop4h 32m
Wed 2/35:20 pm -
1 stop6h 22m
Deal found 9/26![United Airlines logo]()
$363
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3012:10 pm -
2 stops9h 30m
Fri 1/17:55 am -
1 stop10h 15m
Deal found 9/28![Southwest logo]()
$398
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/115:20 am -
1 stop4h 25m
Thu 10/151:55 pm -
1 stop5h 13m
Deal found 9/26![United Airlines logo]()
$467
Last-minute flights from Columbus to KnoxvilleDiscover last-minute flight deals from Columbus to Knoxville. Data last updated October 1, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to Knoxville. Data last updated October 1, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:44 pm -
2 stops20h 07m
Thu 10/156:15 am -
1 stop6h 27m
Deal found 9/26![Multiple Airlines logo]()
$482
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am -
1 stop3h 34m
Thu 10/157:26 am -
1 stop3h 49m
Deal found 9/28![Delta logo]()
$467
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:20 am -
1 stop7h 50m
Thu 10/157:15 am -
2 stops9h 40m
Deal found 9/28![Southwest logo]()
$472
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/123:50 pm -
2 stops6h 55m
Fri 10/1612:50 pm -
1 stop6h 30m
Deal found 9/27![Southwest logo]()
$492
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:35 pm -
1 stop20h 30m
Sat 10/1710:55 am -
2 stops7h 53m
Deal found 9/28![Multiple Airlines logo]()
$476
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:35 pm -
1 stop9h 46m
Mon 10/197:00 am -
2 stops35h 48m
Deal found 9/30![Multiple Airlines logo]()
$445
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:12 pm -
1 stop5h 06m
Tue 10/206:55 pm -
1 stop4h 29m
Deal found 9/26![American Airlines logo]()
$436
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am -
1 stop4h 25m
Thu 10/227:58 pm -
1 stop4h 23m
Deal found 9/28![American Airlines logo]()
$356
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:15 am -
1 stop4h 38m
Mon 11/211:20 am -
1 stop7h 33m
Deal found 9/28![United Airlines logo]()
$363
One-way flights from Columbus to KnoxvilleSearch for one-way flight options from Columbus to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 1, 2026.
Search for one-way flight options from Columbus to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:21 pm -
3 stops41h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$132
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:27 pm -
1 stop4h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![American Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:44 pm -
2 stops23h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:44 pm -
2 stops38h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:13 pm -
3 stops27h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$154
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:25 am -
1 stop3h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Delta logo]()
$174
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:40 am -
2 stops12h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Southwest logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:09 am -
3 stops12h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$187
Find flight deals from Columbus to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Columbus (CMH) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $273 (American Airlines) |
One-way from | $132 (Kiwi.com) |
Popular in | May |
Cheapest in | February |
Average price | $293 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 1, 2026.
Use the filters below to find and compare flights from Columbus Airport to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Mon 11/2
4:21 pm-10:05 am
3 stops41h 44m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$132
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Mon 11/2
7:27 pm-11:47 pm
1 stop4h 20m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$137
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Sun 11/1
7:44 pm-6:52 pm
2 stops23h 08m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$138
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Thu 10/29
7:44 pm-10:05 am
2 stops38h 21m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$141
Quickest round-trip
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Sun 11/1
6:25 am-10:20 am
1 stop3h 55m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$174
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Thu 11/5
9:09 am-10:05 pm
3 stops12h 56m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$187
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Wed 10/14
12:25 pm-9:05 pm
2 stops8h 40m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$289
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Sat 1/30
2:45 pm-7:17 pm
1 stop4h 32m
Knoxville McGhee Tyson
Wed 2/3
5:20 pm-11:42 pm
1 stop6h 22m
$363
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Wed 12/30
12:10 pm-9:40 pm
2 stops9h 30m
Knoxville McGhee Tyson
Fri 1/1
7:55 am-6:10 pm
1 stop10h 15m
$398
ColumbusKnoxville
CMH Columbus - TYS Knoxville McGhee Tyson
CMHTYS
Columbus
Sun 10/11
5:20 am-9:45 am
1 stop4h 25m
Knoxville McGhee Tyson
Thu 10/15
1:55 pm-7:08 pm
1 stop5h 13m
$467
Sorted by cheapest first
Compare providers for flights from Columbus to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbus to Knoxville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Columbus Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbus Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbus Airport-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Columbus Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbus Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Columbus to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Columbus with our price prediction graph.
CMH-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus Airport to Knoxville
Prices
More
What’s the top layover airport for flights from Columbus Airport to Knoxville?
Share of 1-stop round-trip flights from Columbus Airport to Knoxville chosen by Cheapflights users in the past 12 months, using the same layover each way.
Charlotte (CLT) – chosen by Cheapflights users on 50% of 1-stop itineraries from Columbus Airport to Knoxville on Cheapflights.
What’s the cheapest layover airport for flights from Columbus Airport to Knoxville?
Average round-trip fare for 1-stop flights from Columbus Airport to Knoxville, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Charlotte (CLT) is the most affordable 1-stop option, with an average round-trip price of $236.
What’s the fastest layover option from Columbus Airport to Knoxville?
Shortest average travel time for 1-stop one-way flights from Columbus Airport to Knoxville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Charlotte (CLT) have the shortest average one-way travel time for 1-stop routes: 4h 09m.
Which airport typically offers the quickest layover for flights from Columbus Airport to Knoxville?
Average layover duration for 1-stop one-way flights from Columbus Airport to Knoxville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Washington, D.C. (IAD) offer the fastest connection on this route, with an average layover time of 1h 05m.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated October 1, 2026.
Get a feel of what it's like to fly with American Airlines from Columbus Airport to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.4
Crew
7.9
Entertainment
6.8
Overall
7.0
Comfort
7.2
Food
6.4
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Boarding
7.4
Crew
7.9
Entertainment
6.8
Overall
7.0
Comfort
7.2
Food
6.4
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Columbus to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
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Top airline flying from Columbus to Knoxville
Discover the top airline that operate flights from Columbus to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$238 | Average$309 | FlexibilityNo cancel fee | On-time71% |