$120+ Cheap flights from Louisville to Knoxville (SDF - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — TYS
Nov 22 — Nov 291
Round-trip
1 adult, Economy
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Find cheap flights from Louisville to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to Knoxville
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Cheapest flights from Louisville to KnoxvilleExplore the most affordable flight options available from Louisville to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2026.
Explore the most affordable flight options available from Louisville to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2026.
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:05 am -
1 stop5h 50m
Wed 11/256:10 pm -
1 stop3h 32m
Deal found 10/21![Delta logo]()
$239
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:59 pm -
1 stop6h 00m
Wed 11/184:00 pm -
1 stop5h 42m
Deal found 10/21![Delta logo]()
$245
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:14 pm -
1 stop5h 32m
Wed 11/258:04 pm -
1 stop4h 16m
Deal found 10/21![American Airlines logo]()
$295
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:50 am -
2 stops11h 00m
Wed 11/257:15 pm -
1 stop3h 55m
Deal found 10/21![Southwest logo]()
$338
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:04 am -
1 stop3h 41m
Sat 11/711:33 am -
1 stop5h 58m
Deal found 10/20![American Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:42 pm -
1 stop5h 06m
Wed 11/1812:20 pm -
1 stop3h 25m
Deal found 10/18![American Airlines logo]()
$397
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:50 am -
2 stops10h 55m
Sat 11/78:15 am -
1 stop4h 40m
Deal found 10/20![Southwest logo]()
$409
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:59 pm -
1 stop4h 03m
Sun 11/85:40 am -
1 stop3h 17m
Deal found 10/19![Delta logo]()
$490
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:41 pm -
1 stop5h 16m
Sun 10/2510:34 am -
1 stop9h 18m
Deal found 10/19![Allegiant Air logo]()
$604
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/79:10 am -
2 stops8h 35m
Sun 11/87:25 pm -
1 stop2h 50m
Deal found 10/19![Southwest logo]()
$659
Best flights from Louisville to KnoxvilleDiscover carefully curated flight deals from Louisville to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 23, 2026.
Discover carefully curated flight deals from Louisville to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 23, 2026.
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:05 am -
1 stop5h 50m
Wed 11/256:10 pm -
1 stop3h 32m
Deal found 10/21![Delta logo]()
$239
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:42 pm -
1 stop5h 06m
Wed 11/1812:20 pm -
1 stop3h 25m
Deal found 10/18![American Airlines logo]()
$397
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:59 pm -
1 stop6h 00m
Wed 11/184:00 pm -
1 stop5h 42m
Deal found 10/22![Delta logo]()
$245
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:27 am -
1 stop10h 27m
Wed 11/185:45 am -
2 stops11h 17m
Deal found 10/22![United Airlines logo]()
$783
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:55 am -
2 stops10h 59m
Sat 11/79:45 am -
2 stops11h 07m
Deal found 10/20![United Airlines logo]()
$882
Last-minute flights from Louisville to KnoxvilleDiscover last-minute flight deals from Louisville to Knoxville. Data last updated October 23, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to Knoxville. Data last updated October 23, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:41 pm -
1 stop5h 16m
Sun 10/2510:34 am -
1 stop9h 18m
Deal found 10/19![Allegiant Air logo]()
$604
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:04 am -
1 stop3h 41m
Sat 11/711:33 am -
1 stop5h 58m
Deal found 10/20![American Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:50 am -
2 stops10h 55m
Sat 11/78:15 am -
1 stop4h 40m
Deal found 10/20![Southwest logo]()
$409
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:59 pm -
1 stop4h 03m
Sun 11/85:40 am -
1 stop3h 17m
Deal found 10/19![Delta logo]()
$490
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/79:10 am -
2 stops8h 35m
Sun 11/87:25 pm -
1 stop2h 50m
Deal found 10/19![Southwest logo]()
$659
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:59 pm -
1 stop6h 00m
Wed 11/184:00 pm -
1 stop5h 42m
Deal found 10/21![Delta logo]()
$245
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:42 pm -
1 stop5h 06m
Wed 11/1812:20 pm -
1 stop3h 25m
Deal found 10/18![American Airlines logo]()
$397
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:05 am -
1 stop5h 50m
Wed 11/256:10 pm -
1 stop3h 32m
Deal found 10/21![Delta logo]()
$239
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:14 pm -
1 stop5h 32m
Wed 11/258:04 pm -
1 stop4h 16m
Deal found 10/21![American Airlines logo]()
$295
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:50 am -
2 stops11h 00m
Wed 11/257:15 pm -
1 stop3h 55m
Deal found 10/21![Southwest logo]()
$338
One-way flights from Louisville to KnoxvilleSearch for one-way flight options from Louisville to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 23, 2026.
Search for one-way flight options from Louisville to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 23, 2026.
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/135:45 pm -
1 stop6h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Delta logo]()
$120
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/138:30 am -
2 stops10h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Southwest logo]()
$131
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/43:10 pm -
1 stop5h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Southwest logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/139:27 pm -
3 stops40h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$273
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/41:59 pm -
3 stops21h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![United Airlines logo]()
$391
Find flight deals from Louisville to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $239 (Delta) |
One-way from | $120 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 23, 2026.
Use the filters below to find and compare flights from Louisville to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvilleKnoxville
SDF Louisville Intl - TYS Knoxville McGhee Tyson
SDFTYS
Louisville Intl
Wed 1/13
5:45 pm-11:46 pm
1 stop6h 01m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$120
Quickest round-trip
LouisvilleKnoxville
SDF Louisville Intl - TYS Knoxville McGhee Tyson
SDFTYS
Louisville Intl
Wed 1/13
5:46 pm-10:51 pm
1 stop5h 05m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$120
LouisvilleKnoxville
SDF Louisville Intl - TYS Knoxville McGhee Tyson
SDFTYS
Louisville Intl
Wed 1/13
8:30 am-6:40 pm
2 stops10h 10m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$131
LouisvilleKnoxville
SDF Louisville Intl - TYS Knoxville McGhee Tyson
SDFTYS
Louisville Intl
Fri 12/4
3:10 pm-8:50 pm
1 stop5h 40m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$145
LouisvilleKnoxville
SDF Louisville Intl - TYS Knoxville McGhee Tyson
SDFTYS
Louisville Intl
Wed 11/18
8:05 am-1:55 pm
1 stop5h 50m
Knoxville McGhee Tyson
Wed 11/25
6:10 pm-9:42 pm
1 stop3h 32m
$239
LouisvilleKnoxville
SDF Louisville Intl - TYS Knoxville McGhee Tyson
SDFTYS
Louisville Intl
Mon 11/16
5:59 pm-11:59 pm
1 stop6h 00m
Knoxville McGhee Tyson
Wed 11/18
4:00 pm-9:42 pm
1 stop5h 42m
$245
LouisvilleKnoxville
SDF Louisville Intl - TYS Knoxville McGhee Tyson
SDFTYS
Louisville Intl
Wed 1/13
9:27 pm-1:44 pm
3 stops40h 17m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$273
LouisvilleKnoxville
SDF Louisville Intl - TYS Knoxville McGhee Tyson
SDFTYS
Louisville Intl
Fri 12/4
1:59 pm-11:39 am
3 stops21h 40m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$391
LouisvilleKnoxville
SDF Louisville Intl - TYS Knoxville McGhee Tyson
SDFTYS
Louisville Intl
Mon 11/16
5:42 pm-10:48 pm
1 stop5h 06m
Knoxville McGhee Tyson
Wed 11/18
12:20 pm-3:45 pm
1 stop3h 25m
$397
LouisvilleKnoxville
SDF Louisville Intl - TYS Knoxville McGhee Tyson
SDFTYS
Louisville Intl
Mon 11/16
10:27 am-8:54 pm
1 stop10h 27m
Knoxville McGhee Tyson
Wed 11/18
5:45 am-5:02 pm
2 stops11h 17m
$783
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Louisville to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Knoxville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Louisville-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Louisville-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Louisville to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Louisville with our price prediction graph.
SDF-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Louisville to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Newport
Bryson City
Murphy
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