$271+ Cheap flights from Lafayette to Knoxville (LFT - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
LFT — TYS
Sep 16 — Sep 231
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Lafayette to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Lafayette to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Lafayette to KnoxvilleExplore the most affordable flight options available from Lafayette to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.
Explore the most affordable flight options available from Lafayette to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:01 pm -
1 stop5h 21m
Wed 9/166:00 am -
1 stop5h 10m
Deal found 8/15![American Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/135:27 pm -
1 stop4h 55m
Sat 9/196:00 am -
1 stop5h 10m
Deal found 8/17![American Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:17 pm -
1 stop5h 38m
Sat 9/265:40 am -
1 stop6h 01m
Deal found 8/15![Delta logo]()
$310
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1410:35 am -
2 stops9h 08m
Tue 11/175:19 pm -
1 stop4h 54m
Deal found 8/15![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:10 pm -
1 stop5h 42m
Mon 8/316:12 pm -
1 stop4h 29m
Deal found 8/12![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:49 am -
2 stops9h 10m
Mon 8/316:03 am -
1 stop5h 12m
Deal found 8/12![American Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:49 am -
2 stops9h 10m
Sat 9/511:15 am -
2 stops9h 28m
Deal found 8/17![American Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:23 pm -
1 stop5h 09m
Sun 11/226:07 pm -
1 stop4h 57m
Deal found 8/16![American Airlines logo]()
$445
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:45 am -
1 stop7h 20m
Sun 12/275:30 am -
1 stop5h 39m
Deal found 8/12![American Airlines logo]()
$463
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/132:17 pm -
1 stop6h 28m
Mon 10/195:26 pm -
1 stop6h 27m
Deal found 8/14![American Airlines logo]()
$474
Best flights from Lafayette to KnoxvilleDiscover carefully curated flight deals from Lafayette to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 17, 2026.
Discover carefully curated flight deals from Lafayette to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 17, 2026.
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:17 pm -
1 stop5h 38m
Sat 9/265:40 am -
1 stop6h 01m
Deal found 8/15![Delta logo]()
$310
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:04 pm -
1 stop4h 41m
Sat 9/52:21 pm -
1 stop6h 11m
Deal found 8/17![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:49 am -
2 stops9h 10m
Mon 8/315:15 am -
2 stops9h 26m
Deal found 8/12![American Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/711:00 am -
1 stop6h 13m
Fri 1/155:30 am -
1 stop6h 03m
Deal found 8/16![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/62:00 pm -
1 stop4h 34m
Sat 1/97:00 am -
1 stop7h 21m
Deal found 8/15![United Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:10 pm -
1 stop5h 42m
Mon 8/316:12 pm -
1 stop4h 29m
Deal found 8/12![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/22:17 pm -
1 stop4h 48m
Tue 1/55:30 am -
1 stop5h 39m
Deal found 8/13![American Airlines logo]()
$424
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:15 am -
1 stop7h 05m
Wed 12/912:00 pm -
1 stop6h 31m
Deal found 8/12![United Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/135:27 pm -
1 stop4h 55m
Sat 9/192:00 pm -
2 stops9h 55m
Deal found 8/17![American Airlines logo]()
$492
Last-minute flights from Lafayette to KnoxvilleDiscover last-minute flight deals from Lafayette to Knoxville. Data last updated August 17, 2026 and is based on user searches.
Discover last-minute flight deals from Lafayette to Knoxville. Data last updated August 17, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:10 pm -
1 stop5h 42m
Mon 8/316:12 pm -
1 stop4h 29m
Deal found 8/12![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:49 am -
2 stops9h 10m
Mon 8/316:03 am -
1 stop5h 12m
Deal found 8/12![American Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:49 am -
2 stops9h 10m
Sat 9/511:15 am -
2 stops9h 28m
Deal found 8/17![American Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:27 pm -
1 stop4h 51m
Mon 9/76:03 am -
1 stop5h 12m
Deal found 8/12![American Airlines logo]()
$591
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:01 pm -
1 stop5h 21m
Wed 9/166:00 am -
1 stop5h 10m
Deal found 8/15![American Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/135:27 pm -
1 stop4h 55m
Sat 9/196:00 am -
1 stop5h 10m
Deal found 8/17![American Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:17 pm -
1 stop5h 38m
Sat 9/265:40 am -
1 stop6h 01m
Deal found 8/15![Delta logo]()
$310
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:40 am -
2 stops10h 02m
Sat 9/266:00 am -
1 stop5h 10m
Deal found 8/15![American Airlines logo]()
$533
One-way flights from Lafayette to KnoxvilleSearch for one-way flight options from Lafayette to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 17, 2026.
Search for one-way flight options from Lafayette to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 17, 2026.
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:15 pm -
1 stop3h 30m
Deal found 8/14![Delta logo]()
$274
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2410:39 am -
2 stops10h 18m
Deal found 8/13![American Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:15 am -
3 stops10h 34m
Deal found 8/13![United Airlines logo]()
$557
Find flight deals from Lafayette to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Lafayette (LFT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $271 (American Airlines) |
Popular in | February |
Cheapest in | August |
Average price | $308 |
Cheapflights Fare Finder
Customize your flight search to find flights from Lafayette to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
Use the filters below to find and compare flights from Lafayette to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LafayetteKnoxville
LFT Lafayette Regional - TYS Knoxville McGhee Tyson
LFTTYS
Lafayette Regional
Wed 9/23
5:17 pm-11:55 pm
1 stop5h 38m
Knoxville McGhee Tyson
Sat 9/26
5:40 am-10:41 am
1 stop6h 01m
$310
LafayetteKnoxville
LFT Lafayette Regional - TYS Knoxville McGhee Tyson
LFTTYS
Lafayette Regional
Thu 1/7
11:00 am-6:13 pm
1 stop6h 13m
Knoxville McGhee Tyson
Fri 1/15
5:30 am-10:33 am
1 stop6h 03m
$319
LafayetteKnoxville
LFT Lafayette Regional - TYS Knoxville McGhee Tyson
LFTTYS
Lafayette Regional
Tue 9/1
4:04 pm-9:45 pm
1 stop4h 41m
Knoxville McGhee Tyson
Sat 9/5
2:21 pm-7:32 pm
1 stop6h 11m
$349
Quickest round-trip
LafayetteKnoxville
LFT Lafayette Regional - TYS Knoxville McGhee Tyson
LFTTYS
Lafayette Regional
Thu 8/27
5:10 pm-11:52 pm
1 stop5h 42m
Knoxville McGhee Tyson
Mon 8/31
6:12 pm-9:41 pm
1 stop4h 29m
$349
LafayetteKnoxville
LFT Lafayette Regional - TYS Knoxville McGhee Tyson
LFTTYS
Lafayette Regional
Wed 1/6
2:00 pm-7:34 pm
1 stop4h 34m
Knoxville McGhee Tyson
Sat 1/9
7:00 am-1:21 pm
1 stop7h 21m
$351
LafayetteKnoxville
LFT Lafayette Regional - TYS Knoxville McGhee Tyson
LFTTYS
Lafayette Regional
Thu 8/27
10:49 am-8:59 pm
2 stops9h 10m
Knoxville McGhee Tyson
Mon 8/31
5:15 am-1:41 pm
2 stops9h 26m
$389
LafayetteKnoxville
LFT Lafayette Regional - TYS Knoxville McGhee Tyson
LFTTYS
Lafayette Regional
Sat 1/2
2:17 pm-8:05 pm
1 stop4h 48m
Knoxville McGhee Tyson
Tue 1/5
5:30 am-10:09 am
1 stop5h 39m
$424
LafayetteKnoxville
LFT Lafayette Regional - TYS Knoxville McGhee Tyson
LFTTYS
Lafayette Regional
Sat 12/5
5:15 am-1:20 pm
1 stop7h 05m
Knoxville McGhee Tyson
Wed 12/9
12:00 pm-5:31 pm
1 stop6h 31m
$484
LafayetteKnoxville
LFT Lafayette Regional - TYS Knoxville McGhee Tyson
LFTTYS
Lafayette Regional
Sun 9/13
5:27 pm-11:22 pm
1 stop4h 55m
Knoxville McGhee Tyson
Sat 9/19
2:00 pm-10:55 pm
2 stops9h 55m
$492
Cheapest one-way
LafayetteKnoxville
LFT Lafayette Regional - TYS Knoxville McGhee Tyson
LFTTYS
Lafayette Regional
Thu 12/24
5:27 pm-11:41 pm
1 stop5h 14m
$274
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Lafayette to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Lafayette to Knoxville in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Lafayette-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Lafayette-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Lafayette-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Lafayette-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Lafayette-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Lafayette to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Lafayette with our price prediction graph.
LFT-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Lafayette to Knoxville
Prices
More
What’s the top layover airport for flights from Lafayette to Knoxville?
Share of 1-stop round-trip flights from Lafayette to Knoxville chosen by Cheapflights users in the past 12 months, using the same layover each way.
Dallas (DFW) – chosen by Cheapflights users on 75% of 1-stop itineraries from Lafayette to Knoxville on Cheapflights.
What’s the cheapest layover airport for flights from Lafayette to Knoxville?
Average round-trip fare for 1-stop flights from Lafayette to Knoxville, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Dallas (DFW) is the most affordable 1-stop option, with an average round-trip price of $346.
What’s the fastest layover option from Lafayette to Knoxville?
Shortest average travel time for 1-stop one-way flights from Lafayette to Knoxville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Houston (IAH) have the shortest average one-way travel time for 1-stop routes: 4h 31m.
Which airport typically offers the quickest layover for flights from Lafayette to Knoxville?
Average layover duration for 1-stop one-way flights from Lafayette to Knoxville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Houston (IAH) offer the fastest connection on this route, with an average layover time of 0h 58m.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated August 17, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Lafayette to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Lafayette to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Knoxville flight routes
Other flight options
Other flights from Lafayette
Popular flights
Alternative routes for Lafayette to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Lafayette to Knoxville by cabin class
Find flights from Lafayette to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 17, 2026.
Lafayette and Knoxville flights
Browse other Lafayette and Knoxville flight options. Last updated on August 17, 2026.
Other flights from Lafayette
Browse through other flights departing from Lafayette. Flights are based on user searches made on Cheapflights and were last updated on August 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Lafayette to Knoxville
Discover the top 2 airlines that operate flights from Lafayette to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$268 | Average$443 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$288 | Average$352 | FlexibilityNo cancel fee | On-time71% |