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$249+ Cheap flights from Lafayette to Knoxville (LFT - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/20. Fares are subject to change and may not be available on all flights or dates of travel.
LFT — TYS
Mar 22 — Mar 291
Sun 3/22
Sun 3/29
1 adult, Economy
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Cheap flight deals from Lafayette to Knoxville

Cheapest flights from Lafayette to Knoxville
Explore the most affordable flight options available from Lafayette to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2026.

This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:00 am
LFT
-
TYS
1 stop4h 08m
Delta
Wed 3/115:40 am
TYS
-
LFT
1 stop6h 06m
Delta
Deal found 2/20$279
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/213:14 pm
LFT
-
TYS
1 stop3h 46m
Delta
Tue 2/245:35 am
TYS
-
LFT
1 stop6h 04m
Delta
Deal found 2/18$369
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2110:25 am
LFT
-
TYS
2 stops10h 30m
American Airlines
Tue 2/2412:21 pm
TYS
-
LFT
1 stop6h 40m
American Airlines
Deal found 2/18$374
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/257:00 am
LFT
-
TYS
1 stop4h 32m
American Airlines
Mon 7/278:09 pm
TYS
-
LFT
1 stop4h 47m
American Airlines
Deal found 2/19$385
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/410:25 am
LFT
-
TYS
1 stop6h 06m
American Airlines
Sun 3/85:40 am
TYS
-
LFT
1 stop5h 18m
American Airlines
Deal found 2/17$407
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:16 pm
LFT
-
TYS
1 stop5h 12m
American Airlines
Wed 3/119:25 am
TYS
-
LFT
2 stops9h 25m
American Airlines
Deal found 2/20$411
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/192:34 pm
LFT
-
TYS
2 stops8h 25m
American Airlines
Sat 2/215:40 am
TYS
-
LFT
1 stop5h 13m
American Airlines
Deal found 2/17$555
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2812:06 pm
LFT
-
TYS
1 stop6h 49m
United Airlines
Wed 3/47:25 pm
TYS
-
LFT
2 stops17h 00m
United Airlines
Deal found 2/17$604

Find flight deals from Lafayette to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Lafayette (LFT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$279
(Delta)

One-way from

$249
(Delta)

Popular in

February

Cheapest in

March

Average price

$578
Provider with most accurate pricing for Lafayette Regional-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Lafayette Regional-Knoxville McGhee Tyson flights.
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From Lafayette Regional to Knoxville McGhee Tyson
Search Deals
One-way flight from Lafayette Regional to Knoxville McGhee Tyson
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High demand for flights, 1% potential price rise
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Lafayette to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2026.
Use the filters below to find and compare flights from Lafayette to Knoxville that are best for you.

Fly from

Lafayette

Fly to

Knoxville

Route

Depart

Return

Price

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Sat 3/7

6:00 am-11:08 am

1 stop4h 08m

Knoxville McGhee Tyson

Wed 3/11

5:40 am-10:46 am

1 stop6h 06m

$279

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Sat 7/25

7:00 am-12:32 pm

1 stop4h 32m

Knoxville McGhee Tyson

Mon 7/27

8:09 pm-11:56 pm

1 stop4h 47m

$385

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Wed 3/4

10:25 am-5:31 pm

1 stop6h 06m

Knoxville McGhee Tyson

Sun 3/8

5:40 am-9:58 am

1 stop5h 18m

$407

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Sat 3/7

6:16 pm-12:28 am

1 stop5h 12m

Knoxville McGhee Tyson

Wed 3/11

9:25 am-5:50 pm

2 stops9h 25m

$411

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Wed 3/4

4:07 pm-8:47 pm

2 stops27h 40m

Knoxville McGhee Tyson

Sun 3/8

1:53 pm-11:07 am

2 stops22h 14m

$607

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 3/20

5:12 pm-11:57 pm

1 stop5h 45m

$249

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Mon 4/20

4:06 pm-11:41 pm

1 stop6h 35m

$261

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Mon 4/20

2:03 pm-11:55 pm

2 stops8h 52m

$353

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 3/20

10:28 am-9:54 pm

2 stops10h 26m

$485

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 3/20

5:15 am-8:47 pm

3 stops14h 32m

$2,251

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Compare providers for flights from Lafayette to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Lafayette to Knoxville in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Lafayette-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Lafayette-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Lafayette-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Lafayette-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Lafayette-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Lafayette to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Lafayette with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lafayette to Knoxville

What is the cheapest month to book a flight from Lafayette to Knoxville?

Currently, May is the cheapest month in which you can book a flight from Lafayette to Knoxville (average of $144). Flying from Lafayette to Knoxville in February is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated February 20, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Lafayette to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,215 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,215 reviews
Delta
7.9
Good
8,215 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,320 reviews
Delta
7.9
Good
8,215 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Lafayette to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lafayette to Knoxville?

    For as low as $279, Delta can have you in Knoxville from Lafayette in 4h 08m. Lafayette and Knoxville are separated by a distance of 603 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Lafayette to Knoxville round-trip?

    Delta, at $108, was found to be the cheapest airline from Lafayette to Knoxville. An alternate airline flying to your destination would be American Airlines. Delta is priced at 72% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Lafayette to Knoxville that include hotel bookings?

    Yes. In addition to deals on Lafayette to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lafayette to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lafayette to Knoxville.

  • Can I find deals for business class flights from Lafayette to Knoxville?

    Yes. Cheapflights offers flight deals from Lafayette to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lafayette to Knoxville?

    Currently, May is the cheapest month in which you can book a flight from Lafayette to Knoxville (average of $144). Flying from Lafayette to Knoxville in February is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Lafayette to Knoxville

Discover the top 2 airlines that operate flights from Lafayette to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$108Average$373FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$216Average$348FlexibilityNo cancel feeOn-time71%

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