HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$259+ Cheap flights from Lafayette to Knoxville (LFT - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/12. Fares are subject to change and may not be available on all flights or dates of travel.
LFT — TYS
Apr 9 — Apr 161
Thu 4/9
Thu 4/16
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Lafayette to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Lafayette to Knoxville

Cheapest flights from Lafayette to Knoxville
Explore the most affordable flight options available from Lafayette to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.

This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/215:35 am
LFT
-
TYS
1 stop4h 55m
American Airlines
Wed 3/255:40 am
TYS
-
LFT
1 stop5h 18m
American Airlines
Deal found 3/6$299
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1112:03 pm
LFT
-
TYS
1 stop5h 12m
United Airlines
Tue 4/149:00 am
TYS
-
LFT
1 stop7h 31m
United Airlines
Deal found 3/8$359
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1210:51 am
LFT
-
TYS
1 stop7h 40m
American Airlines
Tue 6/165:33 pm
TYS
-
LFT
1 stop6h 59m
American Airlines
Deal found 3/9$394
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/243:10 pm
LFT
-
TYS
1 stop5h 34m
Delta
Wed 7/295:30 am
TYS
-
LFT
1 stop5h 58m
Delta
Deal found 3/8$403
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/225:15 pm
LFT
-
TYS
1 stop3h 29m
Delta
Sat 6/275:30 am
TYS
-
LFT
1 stop5h 58m
Delta
Deal found 3/6$438
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:15 pm
LFT
-
TYS
1 stop5h 31m
Delta
Tue 7/710:05 am
TYS
-
LFT
1 stop5h 21m
Delta
Deal found 3/7$448
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1210:51 am
LFT
-
TYS
1 stop7h 40m
American Airlines
Wed 6/175:33 pm
TYS
-
LFT
1 stop6h 59m
American Airlines
Deal found 3/9$451
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:12 pm
LFT
-
TYS
1 stop5h 45m
Delta
Sun 3/295:40 am
TYS
-
LFT
1 stop6h 06m
Delta
Deal found 3/10$469

Find flight deals from Lafayette to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Lafayette (LFT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$299
(American Airlines)

One-way from

$259
(Delta)

Popular in

February

Cheapest in

March

Average price

$268
Provider with most accurate pricing for Lafayette Regional-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lafayette Regional-Knoxville McGhee Tyson flights.
Search Deals
From Lafayette Regional to Knoxville McGhee Tyson
Search Deals
One-way flight from Lafayette Regional to Knoxville McGhee Tyson
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lafayette to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Lafayette to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Sat 3/21

5:35 am-11:30 am

1 stop4h 55m

Knoxville McGhee Tyson

Wed 3/25

5:40 am-9:58 am

1 stop5h 18m

$299

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Sat 4/11

12:03 pm-6:15 pm

1 stop5h 12m

Knoxville McGhee Tyson

Tue 4/14

9:00 am-3:31 pm

1 stop7h 31m

$359

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 7/24

3:10 pm-9:44 pm

1 stop5h 34m

Knoxville McGhee Tyson

Wed 7/29

5:30 am-10:28 am

1 stop5h 58m

$403

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 6/12

5:30 pm-11:53 pm

1 stop5h 23m

Knoxville McGhee Tyson

Tue 6/16

5:33 pm-11:32 pm

1 stop6h 59m

$414
Quickest round-trip

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Mon 6/22

5:15 pm-9:44 pm

1 stop3h 29m

Knoxville McGhee Tyson

Sat 6/27

5:30 am-10:28 am

1 stop5h 58m

$438

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Thu 7/2

5:15 pm-11:46 pm

1 stop5h 31m

Knoxville McGhee Tyson

Tue 7/7

10:05 am-2:26 pm

1 stop5h 21m

$448

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 6/12

10:51 am-7:31 pm

1 stop7h 40m

Knoxville McGhee Tyson

Wed 6/17

5:33 pm-11:32 pm

1 stop6h 59m

$451

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Sun 3/22

6:20 pm-11:51 pm

1 stop4h 31m

Knoxville McGhee Tyson

Sat 3/28

5:00 pm-10:00 pm

1 stop6h 00m

$482
Cheapest one-way
Quickest one-way

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Sun 4/12

11:27 am-5:45 pm

1 stop5h 18m

$259

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Mon 5/25

1:53 pm-11:59 pm

2 stops9h 06m

$316

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/9

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Compare providers for flights from Lafayette to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Lafayette to Knoxville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Lafayette-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Lafayette-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Lafayette-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Lafayette-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Lafayette-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Lafayette to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Lafayette with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lafayette to Knoxville

What is the cheapest month to book a flight from Lafayette to Knoxville?

Currently, May is the cheapest month in which you can book a flight from Lafayette to Knoxville (average of $144). Flying from Lafayette to Knoxville in April is currently the most expensive (average of $329). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 10, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Lafayette to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,276 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,276 reviews
Delta
7.9
Good
8,276 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,414 reviews
Delta
7.9
Good
8,276 reviews

Comfort

7.9

Entertainment

7.8

Overall

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Lafayette to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lafayette to Knoxville?

    For as low as $299, American Airlines can have you in Knoxville from Lafayette in 4h 55m. Lafayette and Knoxville are separated by a distance of 603 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Lafayette to Knoxville round-trip?

    Delta, at $108, was found to be the cheapest airline from Lafayette to Knoxville. An alternate airline flying to your destination would be American Airlines. Delta is priced at 72% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Lafayette to Knoxville that include hotel bookings?

    Yes. In addition to deals on Lafayette to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lafayette to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lafayette to Knoxville.

  • Can I find deals for business class flights from Lafayette to Knoxville?

    Yes. Cheapflights offers flight deals from Lafayette to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lafayette to Knoxville?

    Currently, May is the cheapest month in which you can book a flight from Lafayette to Knoxville (average of $144). Flying from Lafayette to Knoxville in April is currently the most expensive (average of $329). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Lafayette to Knoxville

Discover the top 2 airlines that operate flights from Lafayette to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$108Average$353FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$231Average$352FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights