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$274+ Cheap flights from Lafayette to Knoxville (LFT - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/7. Fares are subject to change and may not be available on all flights or dates of travel.
LFT — TYS
Jun 14 — Jun 211
Sun 6/14
Sun 6/21
1 adult, Economy
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Cheap flight deals from Lafayette to Knoxville

Cheapest flights from Lafayette to Knoxville
Explore the most affordable flight options available from Lafayette to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 15, 2026.

This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:25 pm
LFT
-
TYS
1 stop5h 30m
American Airlines
Tue 6/165:37 am
TYS
-
LFT
1 stop5h 44m
American Airlines
Deal found 5/13$290
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:15 pm
LFT
-
TYS
1 stop5h 31m
Delta
Mon 11/238:47 am
TYS
-
LFT
1 stop6h 42m
Delta
Deal found 5/13$317
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:27 pm
LFT
-
TYS
1 stop5h 28m
American Airlines
Mon 6/156:07 pm
TYS
-
LFT
1 stop4h 53m
American Airlines
Deal found 5/10$333
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:03 pm
LFT
-
TYS
1 stop5h 49m
Delta
Tue 7/216:05 pm
TYS
-
LFT
1 stop4h 36m
Delta
Deal found 5/12$334
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:27 pm
LFT
-
TYS
1 stop5h 29m
American Airlines
Sat 5/305:36 am
TYS
-
LFT
1 stop5h 45m
American Airlines
Deal found 5/11$339
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:25 pm
LFT
-
TYS
1 stop5h 30m
American Airlines
Mon 6/156:07 pm
TYS
-
LFT
1 stop4h 53m
American Airlines
Deal found 5/11$346
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:36 pm
LFT
-
TYS
1 stop5h 16m
American Airlines
Tue 7/215:36 am
TYS
-
LFT
1 stop5h 46m
American Airlines
Deal found 5/11$347
This United Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:20 am
LFT
-
TYS
1 stop6h 37m
United Airlines
Wed 9/27:15 am
TYS
-
LFT
1 stop5h 00m
United Airlines
Deal found 5/14$365
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:10 pm
LFT
-
TYS
1 stop5h 35m
Delta
Tue 11/247:20 pm
TYS
-
LFT
1 stop3h 45m
Delta
Deal found 5/13$370
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:15 pm
LFT
-
TYS
1 stop3h 30m
Delta
Thu 11/268:47 am
TYS
-
LFT
1 stop6h 42m
Delta
Deal found 5/13$373
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:06 pm
LFT
-
TYS
2 stops7h 48m
American Airlines
Mon 11/2312:08 pm
TYS
-
LFT
1 stop6h 20m
American Airlines
Deal found 5/13$375

Find flight deals from Lafayette to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Lafayette (LFT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 15, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$290
(American Airlines)

One-way from

$274
(Delta)

Popular in

February

Cheapest in

May

Average price

$313
Provider with most accurate pricing for Lafayette Regional-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lafayette Regional-Knoxville McGhee Tyson flights.
Search Deals
From Lafayette Regional to Knoxville McGhee Tyson
Search Deals
One-way flight from Lafayette Regional to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($39 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lafayette to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 15, 2026.
Use the filters below to find and compare flights from Lafayette to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 6/12

5:25 pm-11:55 pm

1 stop5h 30m

Knoxville McGhee Tyson

Wed 6/17

5:37 am-10:21 am

1 stop5h 44m

$290

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 6/12

5:25 pm-11:55 pm

1 stop5h 30m

Knoxville McGhee Tyson

Tue 6/16

5:37 am-10:21 am

1 stop5h 44m

$290
Quickest round-trip

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Tue 7/14

5:03 pm-11:52 pm

1 stop5h 49m

Knoxville McGhee Tyson

Tue 7/21

6:05 pm-9:41 pm

1 stop4h 36m

$334

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Tue 7/14

5:36 pm-11:52 pm

1 stop5h 16m

Knoxville McGhee Tyson

Tue 7/21

5:36 am-10:22 am

1 stop5h 46m

$347

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Sat 8/29

5:20 am-12:57 pm

1 stop6h 37m

Knoxville McGhee Tyson

Wed 9/2

7:15 am-11:15 am

1 stop5h 00m

$365

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Thu 6/11

5:03 pm-11:57 pm

1 stop5h 54m

Knoxville McGhee Tyson

Wed 6/17

3:54 pm-9:51 pm

1 stop6h 57m

$370

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Thu 6/11

5:25 pm-11:55 pm

1 stop5h 30m

Knoxville McGhee Tyson

Wed 6/17

5:37 am-10:21 am

1 stop5h 44m

$449
Cheapest one-way
Quickest one-way

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Sun 6/7

6:00 am-11:09 am

1 stop4h 09m

$274

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Sun 6/7

1:53 pm-11:47 pm

2 stops8h 54m

$532

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Sun 5/31

1:53 pm-11:47 pm

2 stops8h 54m

$601

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/11

Sorted by cheapest first

Compare providers for flights from Lafayette to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Lafayette to Knoxville in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Lafayette-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Lafayette-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Lafayette-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Lafayette-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Lafayette-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Lafayette to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Lafayette with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lafayette to Knoxville

What’s the top layover airport for flights from Lafayette to Knoxville?

Share of 1-stop round-trip flights from Lafayette to Knoxville chosen by Cheapflights users in the past 12 months, using the same layover each way.

Houston (IAH) – chosen by Cheapflights users on 50% of 1-stop itineraries from Lafayette to Knoxville on Cheapflights.

What’s the cheapest layover airport for flights from Lafayette to Knoxville?

Average round-trip fare for 1-stop flights from Lafayette to Knoxville, chosen by Cheapflights users in the past 12 months, with the same layover each way.

Dallas (DFW) is the most affordable 1-stop option, with an average round-trip price of $345.

What’s the fastest layover option from Lafayette to Knoxville?

Shortest average travel time for 1-stop one-way flights from Lafayette to Knoxville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.

Flights via Houston (IAH) have the shortest average one-way travel time for 1-stop routes: 4h 31m.

Which airport typically offers the quickest layover for flights from Lafayette to Knoxville?

Average layover duration for 1-stop one-way flights from Lafayette to Knoxville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.

Flights via Houston (IAH) offer the fastest connection on this route, with an average layover time of 0h 58m.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated May 15, 2026.
Read reviews from past customers who have flown American Airlines from Lafayette to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,662 reviews

Comfort

7.2

Entertainment

6.9

Boarding

7.5

Food

6.4

Overall

7.1

Crew

7.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!
American Airlines
7.1
Good
11,662 reviews
American Airlines
7.1
Good
11,662 reviews

Comfort

7.2

Entertainment

6.9

Boarding

7.5

Food

6.4

Overall

7.1

Crew

7.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Related info for your journey

Find useful and relevant information for your journey from Lafayette to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lafayette to Knoxville?

    For as low as $290, American Airlines can have you in Knoxville from Lafayette in 5h 30m. Lafayette and Knoxville are separated by a distance of 603 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Lafayette to Knoxville round-trip?

    American Airlines, at $288, was found to be the cheapest airline from Lafayette to Knoxville.. American Airlines is priced at 27% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Lafayette to Knoxville that include hotel bookings?

    Yes. In addition to deals on Lafayette to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lafayette to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lafayette to Knoxville.

  • Can I find deals for business class flights from Lafayette to Knoxville?

    Yes. Cheapflights offers flight deals from Lafayette to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Lafayette to Knoxville

Discover the top airline that operate flights from Lafayette to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$288Average$352FlexibilityNo cancel feeOn-time71%

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