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$295+ Cheap flights from Lafayette to Knoxville (LFT - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/18. Fares are subject to change and may not be available on all flights or dates of travel.
LFT — TYS
May 28 — Jun 41
Thu 5/28
Thu 6/4
1 adult, Economy
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Cheap flight deals from Lafayette to Knoxville

Cheapest flights from Lafayette to Knoxville
Explore the most affordable flight options available from Lafayette to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.

This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/123:29 pm
LFT
-
TYS
1 stop5h 30m
Delta
Wed 6/177:33 am
TYS
-
LFT
1 stop4h 24m
Delta
Deal found 4/24$295
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:12 pm
LFT
-
TYS
1 stop4h 44m
American Airlines
Sat 5/235:36 am
TYS
-
LFT
1 stop5h 45m
American Airlines
Deal found 4/23$333
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:12 pm
LFT
-
TYS
1 stop4h 44m
American Airlines
Wed 5/203:58 pm
TYS
-
LFT
1 stop7h 11m
American Airlines
Deal found 4/23$338
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/83:05 pm
LFT
-
TYS
1 stop5h 43m
Delta
Tue 5/1211:56 am
TYS
-
LFT
1 stop5h 37m
Delta
Deal found 4/23$339
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:05 pm
LFT
-
TYS
1 stop5h 00m
United Airlines
Sat 8/157:15 am
TYS
-
LFT
1 stop5h 00m
United Airlines
Deal found 4/25$341
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:03 pm
LFT
-
TYS
2 stops8h 56m
American Airlines
Tue 5/123:58 pm
TYS
-
LFT
1 stop6h 23m
American Airlines
Deal found 4/23$370
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:42 am
LFT
-
TYS
1 stop6h 22m
American Airlines
Wed 5/61:20 pm
TYS
-
LFT
1 stop5h 22m
American Airlines
Deal found 4/28$412

Find flight deals from Lafayette to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Lafayette (LFT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$295
(Delta)

Popular in

February

Cheapest in

September

Average price

$434
Provider with most accurate pricing for Lafayette Regional-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lafayette Regional-Knoxville McGhee Tyson flights.
Search Deals
From Lafayette Regional to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($35 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Lafayette to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Lafayette to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Tue 8/18

11:00 am-6:17 pm

1 stop6h 17m

Knoxville McGhee Tyson

Sun 8/23

7:20 pm-9:59 pm

1 stop3h 39m

$295
Quickest round-trip

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Tue 5/12

5:15 pm-11:56 pm

1 stop5h 41m

Knoxville McGhee Tyson

Sat 5/16

7:27 am-10:35 am

1 stop4h 08m

$339

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 5/8

3:05 pm-9:48 pm

1 stop5h 43m

Knoxville McGhee Tyson

Tue 5/12

11:56 am-4:33 pm

1 stop5h 37m

$339

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Tue 8/11

12:05 pm-6:05 pm

1 stop5h 00m

Knoxville McGhee Tyson

Sat 8/15

7:15 am-11:15 am

1 stop5h 00m

$341

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Fri 5/8

2:03 pm-11:59 pm

2 stops8h 56m

Knoxville McGhee Tyson

Tue 5/12

3:58 pm-9:21 pm

1 stop6h 23m

$370

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Wed 7/8

5:36 pm-11:52 pm

1 stop5h 16m

Knoxville McGhee Tyson

Mon 7/13

3:40 pm-9:58 pm

1 stop7h 18m

$412
Cheapest one-way
Quickest one-way

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Thu 5/7

5:07 pm-11:56 pm

1 stop5h 49m

$445

LafayetteKnoxville

LFT - TYS

LFTTYS

Lafayette Regional

Thu 5/7

5:15 am-8:45 pm

3 stops14h 30m

$1,266

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/26

Sorted by cheapest first

Compare providers for flights from Lafayette to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Lafayette to Knoxville in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Lafayette-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Lafayette-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Lafayette-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Lafayette-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Lafayette-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Lafayette to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Lafayette with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lafayette to Knoxville

How much does it cost to fly round-trip from Lafayette to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 28, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Lafayette to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,467 reviews

Overall

7.9

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,467 reviews
Delta
7.9
Good
8,467 reviews

Overall

7.9

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,677 reviews
Delta
7.9
Good
8,467 reviews

Overall

7.9

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Lafayette to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lafayette to Knoxville?

    For as low as $341, Delta can have you in Knoxville from Lafayette in 5h. Lafayette and Knoxville are separated by a distance of 603 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Lafayette to Knoxville round-trip?

    Delta, at $108, was found to be the cheapest airline from Lafayette to Knoxville. An alternate airline flying to your destination would be American Airlines. Delta is priced at 73% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Lafayette to Knoxville that include hotel bookings?

    Yes. In addition to deals on Lafayette to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lafayette to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lafayette to Knoxville.

  • Can I find deals for business class flights from Lafayette to Knoxville?

    Yes. Cheapflights offers flight deals from Lafayette to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge

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Top 2 airlines flying from Lafayette to Knoxville

Discover the top 2 airlines that operate flights from Lafayette to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$108Average$443FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$279Average$352FlexibilityNo cancel feeOn-time71%

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