HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$50+ Cheap flights from Indiana to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/16. Fares are subject to change and may not be available on all flights or dates of travel.
IND — TYS
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Indiana to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Indiana to Knoxville

Keep the following information in mind while searching for Indiana to Knoxville flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$56
(Booking.com)

One-way from

$50
(Flightnetwork)

Popular in

March

Cheapest in

December

Average price

$274

Good round-trip deal

$78 or less
Provider with most accurate pricing for Indianapolis-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Knoxville McGhee Tyson flights.
Search Deals
From Indiana to Knoxville McGhee Tyson
Search Deals
One-way flight from Indiana to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($79 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2025
Search Deals
Price to beat on a round-trip flight from Indiana to Knoxville McGhee Tyson.
Search Deals

Find flight deals from Indiana to Knoxville

Cheapest flights from Indiana to Knoxville
Explore the most affordable flight options available from Indiana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/237:49 pmSBN - TYS
Nonstop1h 20mAllegiant Air
Fri 6/275:37 pmTYS - SBN
Nonstop1h 22mAllegiant Air
Deal found 4/30$76
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/302:00 pmORD - TYS
Nonstop1h 57mUnited Airlines
Fri 6/67:00 amTYS - ORD
Nonstop1h 57mUnited Airlines
Deal found 4/30$189
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1610:35 amORD - TYS
Nonstop1h 47mAmerican Airlines
Mon 6/306:39 pmTYS - ORD
Nonstop1h 55mAmerican Airlines
Deal found 4/30$191
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/288:07 amIND - TYS
1 stop6h 17mAmerican Airlines
Sat 5/317:50 pmTYS - IND
1 stop4h 48mAmerican Airlines
Deal found 4/30$199
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/308:04 pmMDW - TYS
2 stops25h 36mAllegiant Air
Fri 6/61:29 pmTYS - MDW
Nonstop1h 34mAllegiant Air
Deal found 4/30$202
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/252:00 pmORD - TYS
1 stop6h 16mDelta
Tue 7/292:33 pmTYS - ORD
1 stop5h 16mDelta
Deal found 4/30$209
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/98:26 amSBN - TYS
1 stop5h 31mAmerican Airlines
Tue 9/168:45 pmTYS - SBN
1 stop3h 42mAmerican Airlines
Deal found 4/28$209
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/294:15 pmMDW - TYS
1 stop6h 36mDelta
Wed 6/187:46 amTYS - MDW
1 stop5h 43mDelta
Deal found 4/30$209
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/286:00 amCVG - TYS
1 stop5h 23mDelta
Wed 6/410:25 amTYS - CVG
1 stop4h 39mDelta
Deal found 4/30$209
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/3012:41 pmORD - TYS
2 stops23h 09mMultiple Airlines
Mon 6/212:45 pmTYS - ORD
2 stops21h 05mMultiple Airlines
Deal found 4/30$211
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/266:00 amIND - TYS
1 stop3h 53mDelta
Mon 6/307:46 amTYS - IND
1 stop5h 42mDelta
Deal found 4/29$219
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/301:39 pmCVG - TYS
1 stop4h 23mAmerican Airlines
Fri 6/61:06 pmTYS - CVG
1 stop7h 14mAmerican Airlines
Deal found 4/30$219

Cheapflights Fare Finder

Customize your flight search to find flights from Indiana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Indiana to Knoxville that are best for you.

Fly from

Indiana

Fly to

Knoxville

Route

Depart

Return

Price

South BendKnoxville

SBN - TYS

SBNTYS

South Bend/Michiana

Fri 7/25

7:50 pm-9:10 pm

Nonstop1h 20m

Knoxville McGhee Tyson

Mon 7/28

5:37 pm-7:00 pm

Nonstop1h 23m

$60

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 5/30

2:00 pm-4:57 pm

Nonstop1h 57m

Knoxville McGhee Tyson

Fri 6/6

7:00 am-7:57 am

Nonstop1h 57m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Mon 6/16

10:35 am-1:22 pm

Nonstop1h 47m

Knoxville McGhee Tyson

Mon 6/30

6:39 pm-7:34 pm

Nonstop1h 55m

$191

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Wed 5/28

8:07 am-2:24 pm

1 stop6h 17m

Knoxville McGhee Tyson

Sat 5/31

7:50 pm-12:38 am

1 stop4h 48m

$199

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 5/30

8:04 pm-10:40 pm

2 stops25h 36m

Knoxville McGhee Tyson

Fri 6/6

1:29 pm-2:03 pm

Nonstop1h 34m

$202

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 7/25

2:00 pm-9:16 pm

1 stop6h 16m

Knoxville McGhee Tyson

Tue 7/29

2:33 pm-6:49 pm

1 stop5h 16m

$209

South BendKnoxville

SBN - TYS

SBNTYS

South Bend/Michiana

Fri 7/25

2:14 pm-5:32 pm

1 stop3h 18m

Knoxville McGhee Tyson

Mon 7/28

5:12 pm-8:44 pm

1 stop3h 32m

$209

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 5/29

4:15 pm-11:51 pm

1 stop6h 36m

Knoxville McGhee Tyson

Wed 6/18

7:46 am-12:29 pm

1 stop5h 43m

$209

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Wed 5/28

6:00 am-11:23 am

1 stop5h 23m

Knoxville McGhee Tyson

Wed 6/4

10:25 am-3:04 pm

1 stop4h 39m

$209

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 5/30

12:41 pm-12:50 pm

2 stops23h 09m

Knoxville McGhee Tyson

Mon 6/2

12:45 pm-8:50 am

2 stops21h 05m

$211

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 42 results
1
2
3
...
5

Best time to book a flight from Indiana to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Knoxville

What is the cheapest month to book a flight from Indiana to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Indiana to Knoxville (average of $296). Flying from Indiana to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to TYS?

Find hourly flight availability from Indiana to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Indiana to Knoxville as you normally would.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated May 1, 2025.
See what other customers who have flown with Delta, United Airlines and Allegiant Air from Indiana to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,934 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
6.0
Okay
3,287 reviews
Delta
8.0
Very good
7,934 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Indiana to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Indiana?

    If you book a flight to Knoxville from Indiana, you will be flying to McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • What are the cheapest airlines to fly from Indiana to Knoxville one-way?

    The cheapest airlines for a one-way flight from Indiana to Knoxville are Allegiant Air ($50), Frontier ($110), and American Airlines ($120).

  • What are the most popular routes from Indiana to Knoxville?

    Most travelers choose Chicago O'Hare Intl - Knoxville McGhee Tyson, Chicago Midway - Knoxville McGhee Tyson or Indianapolis - Knoxville McGhee Tyson when deciding on the best route from Indiana to Knoxville.

  • Can I find deals for flights from Indiana to Knoxville that include hotel bookings?

    Yes. In addition to deals on Indiana to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Knoxville.

  • Can I find deals for business class flights from Indiana to Knoxville?

    Yes. Cheapflights offers flight deals from Indiana to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Indiana to Knoxville (average of $296). Flying from Indiana to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indiana?

Book flights to Indiana if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Indiana to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Nashville flights
Newark to Nashville flights
LaGuardia to Nashville flights
Los Angeles to Nashville flights
Reagan-National to Nashville flights
Dallas/Fort Worth to Nashville flights
Boston to Nashville flights
O'Hare Intl to Nashville flights
Seattle to Nashville flights
Denver to Nashville flights
Baltimore to Nashville flights
Dulles Intl to Nashville flights
San Francisco to Nashville flights
Ontario to Nashville flights
Philadelphia to Nashville flights
Minneapolis to Nashville flights
O'Hare Intl to Knoxville flights
Sky Harbor Intl to Nashville flights
Raleigh to Nashville flights
Fort Lauderdale to Nashville flights
Santa Ana to Nashville flights
Portland to Nashville flights
Newark to Memphis flights
Orlando to Nashville flights
Burbank to Nashville flights
Detroit to Nashville flights
LaGuardia to Memphis flights
Dallas/Fort Worth to Knoxville flights
San Diego to Nashville flights
Hobby to Nashville flights
O'Hare Intl to Memphis flights
LaGuardia to Knoxville flights
John F Kennedy Intl to Knoxville flights
Hartford to Nashville flights
Salt Lake City to Nashville flights
Philadelphia to Knoxville flights
Rochester to Nashville flights
Charlotte to Nashville flights
Los Angeles to Memphis flights
Cleveland to Nashville flights
Miami to Nashville flights
Midway to Nashville flights
Dulles Intl to Memphis flights
Baltimore to Memphis flights
Sacramento to Nashville flights
Denver to Knoxville flights
Hobby to Knoxville flights
Dulles Intl to Knoxville flights
John F Kennedy Intl to Memphis flights
Las Vegas to Nashville flights

Top 4 airlines flying from Indiana to Knoxville

Discover the top 4 airlines that operate flights from Indiana to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$74Average$82FlexibilityNo cancel feeOn-time88%
DeltaCheapest$198Average$313FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$208Average$370FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$213Average$359FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.