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$740+ Cheap flights from Guayaquil (GYE) to Knoxville (TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — TYS
May 4 — May 111
Sun 5/4
Sun 5/11
1 adult, Economy
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Cheap flight deals from Guayaquil to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$1,111
(Mytrip)
Provider with most accurate pricing for Guayaquil Jose Joaquin de Olmedo-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Guayaquil Jose Joaquin de Olmedo-Knoxville McGhee Tyson flights.
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From Guayaquil Jose Joaquin de Olmedo to Knoxville McGhee Tyson
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Find flight deals from Guayaquil to Knoxville

Cheapest flights from Guayaquil to Knoxville
Explore the most affordable flight options available from Guayaquil to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/208:28 amGYE - TYS
2 stops34h 06mUnited Airlines
Mon 11/105:20 pmTYS - GYE
2 stops30h 21mUnited Airlines
Deal found 4/28$740
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/207:30 amGYE - TYS
1 stop14h 42mAmerican Airlines
Mon 11/105:12 amTYS - GYE
2 stops16h 48mAmerican Airlines
Deal found 4/28$820
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/112:04 amGYE - TYS
2 stops38h 59mMultiple Airlines
Sun 5/43:52 pmTYS - GYE
3 stops41h 43mMultiple Airlines
Deal found 4/28$967

Cheapflights Fare Finder

Customize your flight search to find flights from Guayaquil to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from Guayaquil to Knoxville that are best for you.

Fly from

Guayaquil

Fly to

Knoxville

Route

Depart

Return

Price

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Fri 5/2

4:15 am-4:03 pm

3 stops34h 48m

Knoxville McGhee Tyson

Sun 5/4

5:50 am-2:05 am

2 stops45h 15m

$1,111

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Fri 5/2

6:00 am-11:29 pm

1 stop16h 29m

Knoxville McGhee Tyson

Sun 5/4

6:55 am-8:53 pm

1 stop14h 58m

$1,558

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Compare providers for flights from Guayaquil to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guayaquil to Knoxville in April.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Guayaquil-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guayaquil-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guayaquil-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Guayaquil-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Guayaquil to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to Knoxville

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 29, 2025.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Boarding

7.5

Overall

7.2

Crew

8.0

Food

6.5

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Boarding

7.5

Overall

7.2

Crew

8.0

Food

6.5

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from Guayaquil to Knoxville round-trip?

    Currently priced at $1,558, American Airlines will fly you from Guayaquil to Knoxville and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip.

  • Can I find deals for flights from Guayaquil to Knoxville that include hotel bookings?

    Yes. In addition to deals on Guayaquil to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to Knoxville.

  • Can I find deals for business class flights from Guayaquil to Knoxville?

    Yes. Cheapflights offers flight deals from Guayaquil to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guayaquil to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Guayaquil to Knoxville (average of $296). Flying from Guayaquil to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guayaquil?

Book flights to Guayaquil if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Alternative routes for Guayaquil to Knoxville

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Top airline flying from Guayaquil to Knoxville

Discover the top airline that operate flights from Guayaquil to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$388Average$654FlexibilityNo cancel feeOn-time69%

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