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$596+ Cheap flights from Guayaquil (GYE) to Knoxville (TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/26. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — TYS
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Guayaquil to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$596
(United Airlines)
From Guayaquil Jose Joaquin de Olmedo to Knoxville McGhee Tyson
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Find flight deals from Guayaquil to Knoxville

Cheapest flights from Guayaquil to Knoxville
Explore the most affordable flight options available from Guayaquil to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/268:32 amGYE - TYS
2 stops34h 21mUnited Airlines
Tue 9/97:20 amTYS - GYE
2 stops19h 45mUnited Airlines
Deal found 7/27$596
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/208:15 amGYE - TYS
1 stop14h 20mAmerican Airlines
Mon 11/107:20 pmTYS - GYE
2 stops27h 20mAmerican Airlines
Deal found 7/29$708
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/278:40 pmGYE - TYS
2 stops43h 39mDelta
Sun 9/77:10 amTYS - GYE
2 stops32h 00mDelta
Deal found 7/27$733
This Avianca deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/283:15 amGYE - TYS
3 stops30h 13mAvianca
Tue 9/95:45 amTYS - GYE
2 stops21h 20mAvianca
Deal found 7/27$788
This LATAM Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/103:20 pmGYE - TYS
2 stops18h 22mLATAM Airlines
Mon 9/2912:01 pmTYS - GYE
2 stops11h 22mLATAM Airlines
Deal found 7/27$811

Cheapflights Fare Finder

 
Customize your flight search to find flights from Guayaquil to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Guayaquil to Knoxville that are best for you.

Fly from

Guayaquil

Fly to

Knoxville

Route

Depart

Return

Price

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Tue 8/26

8:32 am-7:53 pm

2 stops34h 21m

Knoxville McGhee Tyson

Mon 9/8

5:10 pm-11:37 pm

2 stops31h 27m

$596

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Mon 10/20

8:15 am-11:35 pm

1 stop14h 20m

Knoxville McGhee Tyson

Mon 11/10

7:20 pm-10:40 pm

2 stops27h 20m

$708

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Wed 8/27

8:40 pm-5:19 pm

2 stops43h 39m

Knoxville McGhee Tyson

Sun 9/7

7:10 am-2:10 pm

2 stops32h 00m

$733

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Thu 8/28

3:15 am-10:28 am

3 stops30h 13m

Knoxville McGhee Tyson

Tue 9/9

5:45 am-2:05 am

2 stops21h 20m

$788

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Wed 9/10

3:20 pm-10:42 am

2 stops18h 22m

Knoxville McGhee Tyson

Mon 9/29

12:01 pm-10:23 pm

2 stops11h 22m

$811

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Best time to book a flight from Guayaquil to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 29, 2025.
Get a feel of what it's like to fly with Delta, LATAM Airlines, and United Airlines from Guayaquil to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,977 reviews

Food

7.3

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
Delta
8.0
Very good
7,977 reviews
Delta
8.0
Very good
7,977 reviews

Food

7.3

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
LATAM Airlines
7.5
Good
1,821 reviews
Delta
8.0
Very good
7,977 reviews

Food

7.3

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
United Airlines
7.4
Good
8,899 reviews
Delta
8.0
Very good
7,977 reviews

Food

7.3

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,977 reviews

Food

7.3

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
Avianca
6.7
Okay
2,386 reviews
Delta
8.0
Very good
7,977 reviews

Food

7.3

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Guayaquil to Knoxville round-trip?

    Currently priced at $596, United Airlines will fly you from Guayaquil to Knoxville and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and Delta - these airlines can fly you to your destination from $708 and $733, respectively.

  • Can I find deals for flights from Guayaquil to Knoxville that include hotel bookings?

    Yes. In addition to deals on Guayaquil to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to Knoxville.

  • Can I find deals for business class flights from Guayaquil to Knoxville?

    Yes. Cheapflights offers flight deals from Guayaquil to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guayaquil to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Guayaquil to Knoxville (average of $294). Flying from Guayaquil to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Alternative routes for Guayaquil to Knoxville

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Top airline flying from Guayaquil to Knoxville

Discover the top airline that operate flights from Guayaquil to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$388Average$654FlexibilityNo cancel feeOn-time69%

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