$436+ Cheap flights from Greenville, NC to Knoxville (PGV - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
PGV — TYS
Oct 24 — Oct 311
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to Knoxville
Cheapest
Best
Last-minute
Cheapest flights from Greenville to KnoxvilleExplore the most affordable flight options available from Greenville to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
Explore the most affordable flight options available from Greenville to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:05 am -
1 stop3h 27m
Sat 10/316:56 am -
1 stop3h 36m
Deal found 9/24![American Airlines logo]()
$436
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:58 pm -
1 stop5h 57m
Fri 10/97:58 pm -
1 stop3h 58m
Deal found 9/20![American Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:20 pm -
2 stops10h 39m
Sat 10/107:58 pm -
1 stop3h 58m
Deal found 9/21![American Airlines logo]()
$642
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:58 pm -
1 stop3h 51m
Sun 10/186:56 am -
1 stop3h 36m
Deal found 9/20![American Airlines logo]()
$716
Best flights from Greenville to KnoxvilleDiscover carefully curated flight deals from Greenville to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
Discover carefully curated flight deals from Greenville to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:05 am -
1 stop3h 27m
Sat 10/316:56 am -
1 stop3h 36m
Deal found 9/24![American Airlines logo]()
$436
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:24 am -
1 stop3h 14m
Sat 10/106:56 am -
1 stop3h 36m
Deal found 9/21![American Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:58 pm -
1 stop3h 51m
Sun 10/186:56 am -
1 stop3h 36m
Deal found 9/20![American Airlines logo]()
$716
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:58 pm -
1 stop5h 57m
Sun 10/186:56 am -
1 stop3h 36m
Deal found 9/20![American Airlines logo]()
$716
Last-minute flights from Greenville to KnoxvilleDiscover last-minute flight deals from Greenville to Knoxville. Data last updated September 24, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to Knoxville. Data last updated September 24, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:58 pm -
1 stop5h 57m
Fri 10/97:58 pm -
1 stop3h 58m
Deal found 9/20![American Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:20 pm -
2 stops10h 39m
Sat 10/107:58 pm -
1 stop3h 58m
Deal found 9/21![American Airlines logo]()
$642
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:58 pm -
1 stop3h 51m
Sun 10/186:56 am -
1 stop3h 36m
Deal found 9/20![American Airlines logo]()
$716
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:05 am -
1 stop3h 27m
Sat 10/316:56 am -
1 stop3h 36m
Deal found 9/24![American Airlines logo]()
$436
Find flight deals from Greenville to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (PGV) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $436 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
Use the filters below to find and compare flights from Greenville to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleKnoxville
PGV Pitt-Greenville - TYS Knoxville McGhee Tyson
PGVTYS
Pitt-Greenville
Sat 10/24
5:05 am-8:32 am
1 stop3h 27m
Knoxville McGhee Tyson
Sat 10/31
6:56 am-10:32 am
1 stop3h 36m
$436
Quickest round-trip
GreenvilleKnoxville
PGV Pitt-Greenville - TYS Knoxville McGhee Tyson
PGVTYS
Pitt-Greenville
Tue 10/6
6:24 am-9:38 am
1 stop3h 14m
Knoxville McGhee Tyson
Sat 10/10
6:56 am-10:32 am
1 stop3h 36m
$467
GreenvilleKnoxville
PGV Pitt-Greenville - TYS Knoxville McGhee Tyson
PGVTYS
Pitt-Greenville
Thu 10/15
5:58 pm-9:49 pm
1 stop3h 51m
Knoxville McGhee Tyson
Sun 10/18
6:56 am-10:32 am
1 stop3h 36m
$716
GreenvilleKnoxville
PGV Pitt-Greenville - TYS Knoxville McGhee Tyson
PGVTYS
Pitt-Greenville
Fri 10/16
5:58 pm-11:55 pm
1 stop5h 57m
Knoxville McGhee Tyson
Sun 10/18
6:56 am-10:32 am
1 stop3h 36m
$716
Sorted by cheapest first
Compare providers for flights from Greenville to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Knoxville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville, North Carolina-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville, North Carolina-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville, North Carolina-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville, North Carolina-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville, North Carolina-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Greenville with our price prediction graph.
PGV-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Greenville to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
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