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$59+ Cheap flights from Denver to Knoxville (DEN - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — TYS
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Denver Intl to Knoxville McGhee Tyson are usually found in September or August, booked 46 days in advance, depart on a Thursday or Sunday and return on a Thursday

Cheap flight deals from Denver to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$98
(Mytrip)

Popular in

March

Cheapest in

September

Average price

$248

Good round-trip deal

$161 or less

Good one-way deal

$106 or less
From Denver Intl to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 5% potential increase in price ($14 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Price to beat on a round-trip flight from Denver Intl to Knoxville McGhee Tyson.
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Price to beat on a one-way flight from Denver Intl to Knoxville McGhee Tyson.
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Find flight deals from Denver to Knoxville

Cheapest flights from Denver to Knoxville
Explore the most affordable flight options available from Denver to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2111:58 amDEN - TYS
Nonstop2h 45mAllegiant Air
Sun 8/2410:00 amTYS - DEN
Nonstop3h 08mAllegiant Air
Deal found 6/11$98
This Cheapflightsfares deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/42:52 pmDEN - TYS
Nonstop2h 49mMultiple Airlines
Sun 9/77:00 amTYS - DEN
Nonstop3h 06mMultiple Airlines
Deal found 6/11$148
This Cheapflightsfares deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/62:52 pmDEN - TYS
Nonstop2h 49mFrontier
Thu 10/98:22 pmTYS - DEN
Nonstop3h 22mFrontier
Deal found 6/12$156
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/136:00 amDEN - TYS
1 stop5h 38mAmerican Airlines
Wed 8/206:05 amTYS - DEN
1 stop6h 01mAmerican Airlines
Deal found 6/11$209
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1512:59 amDEN - TYS
1 stop7h 28mDelta
Wed 8/206:36 amTYS - DEN
1 stop5h 19mDelta
Deal found 6/10$237
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/282:44 pmDEN - TYS
1 stop5h 51mUnited Airlines
Tue 7/14:35 pmTYS - DEN
Nonstop3h 15mUnited Airlines
Deal found 6/11$269

Cheapflights Fare Finder

Customize your flight search to find flights from Denver to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Denver to Knoxville that are best for you.

Fly from

Denver

Fly to

Knoxville

Route

Depart

Return

Price

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 8/21

11:58 am-4:43 pm

Nonstop2h 45m

Knoxville McGhee Tyson

Sun 8/24

10:00 am-11:08 am

Nonstop3h 08m

$98

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 9/4

2:52 pm-7:41 pm

Nonstop2h 49m

Knoxville McGhee Tyson

Sun 9/7

7:00 am-8:06 am

Nonstop3h 06m

$148

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 8/7

11:41 am-4:29 pm

Nonstop2h 48m

Knoxville McGhee Tyson

Sun 8/10

5:25 pm-6:40 pm

Nonstop3h 15m

$179

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Wed 8/13

6:00 am-1:38 pm

1 stop5h 38m

Knoxville McGhee Tyson

Wed 8/20

6:05 am-10:06 am

1 stop6h 01m

$209

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 8/15

12:59 am-10:27 am

1 stop7h 28m

Knoxville McGhee Tyson

Wed 8/20

6:36 am-9:55 am

1 stop5h 19m

$237

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sat 6/28

2:44 pm-10:35 pm

1 stop5h 51m

Knoxville McGhee Tyson

Tue 7/1

4:35 pm-5:50 pm

Nonstop3h 15m

$254

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sun 9/28

8:56 am-1:43 pm

Nonstop2h 47m

$59

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Mon 9/1

1:34 pm-6:25 pm

Nonstop2h 51m

$99

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Mon 9/1

11:59 pm-9:38 am

1 stop7h 39m

$105

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sun 9/28

9:15 am-5:47 pm

2 stops30h 32m

$201

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 12 results
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Best time to book a flight from Denver to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Knoxville

How far ahead should I book a flight from Denver to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Denver to Knoxville. Price data was last updated on June 9, 2025.

The price you pay for your flight from Denver to Knoxville may vary depending on when you book. For the best chance of a lower fare, look to book 46 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Denver to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Denver to Knoxville (average of $296). Flying from Denver to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to TYS?

Find hourly flight availability from Denver to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

It’s typically best to fly out from Denver to Knoxville at noon. Doing so could potentially save you 47% on the flight price compared to flying in the afternoon, which is usually more expensive.

What is the cheapest day to fly from Denver to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Denver to Knoxville. Price data was last updated on June 8, 2025.

Travelers seeking maximum savings on their Denver to Knoxville flight should consider departing on Saturday at noon when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Denver to Knoxville

Explore weekly flight availability from Denver to Knoxville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 12, 2025.

The most flights from DEN to TYS are scheduled on a Thursday (4 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated June 12, 2025.
Get a feel of what it's like to fly with Delta, United Airlines and Allegiant Air from Denver to Knoxville by reading reviews from past customers. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Allegiant Air
7.3
Good
725 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Frontier
6.0
Okay
3,295 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Denver to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Denver to Knoxville?

    Booking a flight from Denver Intl (DEN) to Knoxville McGhee Tyson (TYS) is your only option if you wish to fly from Denver to Knoxville. On a typical day, there are 2 flights from Denver Intl to McGhee Tyson, all of which are around 2h 38m for a nonstop flight. You can also purchase a plane ticket from 5 airlines when you book a flight from Denver Intl to Knoxville.

  • How popular is this Denver to Knoxville flight route?

    Within the past month, 1 users have taken a look at flights from Denver Intl to Knoxville McGhee Tyson.

  • What are the cheapest airlines flying from Denver to Knoxville round-trip?

    Our cheapest airline available from Denver to Knoxville is Allegiant Air. Our recent data shows that you can find tickets from as low as $98 on this airline. Additional options worth looking into are Frontier and American Airlines, starting at $179 and $209 round-trip. These flights start at 60% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Denver to Knoxville one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $99. Users have also found prices from $105 and $121 on American Airlines and Allegiant Air, respectively.

  • What are the most reliable airlines from Denver to Knoxville?

    The top 3 most reliable airlines when flying from Denver to Knoxville are Frontier (91%), United Airlines (78%) and Allegiant Air (77%).

  • What are the cheapest flights from Denver to Knoxville?

    Looking for the cheapest flight from Denver to Knoxville? While on average our users pay $220, our data indicates the cheapest price to be $68. The most popular route (Denver Intl - Knoxville McGhee Tyson), is priced around $98.

  • Can I find deals for flights from Denver to Knoxville that include hotel bookings?

    Yes. In addition to deals on Denver to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Knoxville.

  • Can I find deals for business class flights from Denver to Knoxville?

    Yes. Cheapflights offers flight deals from Denver to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Denver to Knoxville (average of $296). Flying from Denver to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Denver?

Book flights to Denver if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Top 5 airlines flying from Denver to Knoxville

Discover the top 5 airlines that operate flights from Denver to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$58Average$137FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$67Average$125FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$198Average$299FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$233Average$455FlexibilityNo cancel feeOn-time69%
DeltaCheapest$237Average$293FlexibilityNo cancel feeOn-timeN/A

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