HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$58+ Cheap flights from Denver to Knoxville (DEN - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — TYS
Dec 25 — Jan 11
Thu 12/25
Thu 1/1
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Denver to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Denver Intl to Knoxville McGhee Tyson are usually found in August or April, booked 54 days in advance, depart on a Thursday or Sunday and return on a Thursday

Find flight deals from Denver to Knoxville

Cheapest flights from Denver to Knoxville
Explore the most affordable flight options available from Denver to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 25, 2025.

This Mytrip deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:33 amDEN - TYS
Nonstop2h 38mAllegiant Air
Thu 12/186:30 amTYS - DEN
Nonstop3h 13mAllegiant Air
Deal found 11/24$93
This Mytrip deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:33 amDEN - TYS
Nonstop2h 38mMultiple Airlines
Mon 12/154:52 pmTYS - DEN
Nonstop3h 31mMultiple Airlines
Deal found 11/23$107
This FlightHub deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:33 amDEN - TYS
Nonstop2h 38mAllegiant Air
Sun 12/146:30 amTYS - DEN
Nonstop3h 13mAllegiant Air
Deal found 11/23$109
This Kiwi.com deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/811:12 amDEN - TYS
Nonstop2h 45mFrontier
Mon 12/154:52 pmTYS - DEN
Nonstop3h 31mFrontier
Deal found 11/25$111
This CheapOair deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/811:12 amDEN - TYS
Nonstop2h 45mFrontier
Thu 12/114:52 pmTYS - DEN
Nonstop3h 31mFrontier
Deal found 11/23$112
This Kiwi.com deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:33 amDEN - TYS
Nonstop2h 38mMultiple Airlines
Thu 12/114:52 pmTYS - DEN
Nonstop3h 31mMultiple Airlines
Deal found 11/25$123
This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/711:12 amDEN - TYS
Nonstop2h 45mFrontier
Tue 12/234:46 pmTYS - DEN
Nonstop3h 31mFrontier
Deal found 11/23$146
This Kiwi.com deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1411:12 amDEN - TYS
Nonstop2h 45mFrontier
Thu 12/254:26 pmTYS - DEN
Nonstop3h 31mFrontier
Deal found 11/25$148
This Frontier deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1511:12 amDEN - TYS
Nonstop2h 45mFrontier
Thu 12/254:26 pmTYS - DEN
Nonstop3h 31mFrontier
Deal found 11/25$149
This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/711:12 amDEN - TYS
Nonstop2h 45mFrontier
Mon 12/224:46 pmTYS - DEN
Nonstop3h 31mFrontier
Deal found 11/23$155
This Kiwi.com deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1411:12 amDEN - TYS
Nonstop2h 45mMultiple Airlines
Mon 12/156:10 pmTYS - DEN
1 stop30h 54mMultiple Airlines
Deal found 11/25$157

Cheap flight deals from Denver to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 25, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$93
(Mytrip)

One-way from

$58
(Cheapflightsfares)

Popular in

March

Cheapest in

August

Average price

$241

Good round-trip deal

$187 or less

Good one-way deal

$124 or less
Provider with most accurate pricing for Denver Intl-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Knoxville McGhee Tyson flights.
Search Deals
From Denver Intl to Knoxville McGhee Tyson
Search Deals
One-way flight from Denver Intl to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($6 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from Denver Intl to Knoxville McGhee Tyson.
Search Deals
Price to beat on a one-way flight from Denver Intl to Knoxville McGhee Tyson.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 25, 2025.
Use the filters below to find and compare flights from Denver to Knoxville that are best for you.

Fly from

Denver

Fly to

Knoxville

Route

Depart

Return

Price

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Tue 1/20

6:00 am-1:50 pm

1 stop5h 50m

Knoxville McGhee Tyson

Fri 1/23

7:30 am-1:33 pm

1 stop8h 03m

$249

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 1/9

6:00 am-1:24 pm

1 stop5h 24m

Knoxville McGhee Tyson

Mon 1/12

7:20 pm-12:30 am

1 stop7h 10m

$249

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 12/18

5:45 am-2:52 pm

1 stop7h 07m

Knoxville McGhee Tyson

Wed 1/7

7:30 am-1:33 pm

1 stop8h 03m

$249

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sun 12/28

11:59 pm-10:56 am

1 stop8h 57m

Knoxville McGhee Tyson

Sun 1/11

7:20 pm-12:30 am

1 stop7h 10m

$249

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 1/8

6:00 am-3:19 pm

1 stop7h 19m

Knoxville McGhee Tyson

Sun 1/11

5:40 am-9:37 am

1 stop5h 57m

$249

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 1/22

7:10 am-4:19 pm

1 stop7h 09m

Knoxville McGhee Tyson

Sun 1/25

7:30 am-1:33 pm

1 stop8h 03m

$249

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sat 2/21

5:31 pm-10:30 pm

Nonstop2h 59m

Knoxville McGhee Tyson

Sat 2/28

9:40 am-4:23 pm

1 stop8h 43m

$265

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sun 12/14

5:45 am-1:44 pm

1 stop5h 59m

Knoxville McGhee Tyson

Wed 12/17

8:35 am-12:11 pm

1 stop5h 36m

$274

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sun 12/7

12:50 am-9:38 am

1 stop6h 48m

Knoxville McGhee Tyson

Fri 12/12

7:59 pm-12:07 am

1 stop6h 08m

$299

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sun 12/7

8:33 am-1:11 pm

Nonstop2h 38m

$58

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/23

Showing 1-10 of 18 results
1
2

Compare providers for flights from Denver to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Knoxville in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars
CheapTicketsDealPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Denver-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Denver-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Denver-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Denver-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Denver to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Knoxville

How far ahead should I book a flight from Denver to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Denver to Knoxville. Price data was last updated on November 21, 2025.

The price you pay for your flight from Denver to Knoxville may vary depending on when you book. For the best chance of a lower fare, look to book 54 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Denver to Knoxville?

Currently, February is the cheapest month in which you can book a flight from Denver to Knoxville (average of $57). Flying from Denver to Knoxville in January is currently the most expensive (average of $99). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to TYS?

Find hourly flight availability from Denver to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 25, 2025.

It’s typically best to fly out from Denver to Knoxville at noon. Doing so could potentially save you 32% on the flight price compared to flying in the afternoon, which is usually more expensive.

What is the cheapest day to fly from Denver to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Denver to Knoxville. Price data was last updated on November 2, 2025.

Travelers seeking maximum savings on their Denver to Knoxville flight should consider departing on Tuesday at noon when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Denver to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated November 25, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Denver to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,043 reviews
Delta
7.9
Good
7,998 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,042 reviews
Delta
7.9
Good
7,998 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Allegiant Air
7.2
Good
700 reviews
Delta
7.9
Good
7,998 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Frontier
5.8
Fair
3,097 reviews
Delta
7.9
Good
7,998 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Denver to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Denver to Knoxville?

    Booking a flight from Denver Intl (DEN) to Knoxville McGhee Tyson (TYS) is your only option if you wish to fly from Denver to Knoxville. On a typical day, there are 2 flights from Denver Intl to McGhee Tyson, all of which are around 2h 38m for a nonstop flight. You can also purchase a plane ticket from 5 airlines when you book a flight from Denver Intl to Knoxville.

  • How popular is this Denver to Knoxville flight route?

    Within the past month, 5 users have taken a look at flights from Denver Intl to Knoxville McGhee Tyson.

  • How long is the flight from Denver to Knoxville?

    Delta and United Airlines can get you from Denver to Knoxville in just under 5h 24m. Your travel time can differ by up to 26m. Denver and Knoxville are separated by a distance of 1159 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Denver to Knoxville round-trip?

    Our cheapest airline available from Denver to Knoxville is Allegiant Air. Our recent data shows that you can find tickets from as low as $63 on this airline. Additional options worth looking into are Frontier and Delta, starting at $83 and $133 round-trip. These flights start at 75% lower than the current average price 3 months from now.

  • What are the most reliable airlines from Denver to Knoxville?

    The top 3 most reliable airlines when flying from Denver to Knoxville are Frontier (88%), United Airlines (87%) and Allegiant Air (86%).

  • What are the cheapest flights from Denver to Knoxville?

    Looking for the cheapest flight from Denver to Knoxville? While on average our users pay $230, our data indicates the cheapest price to be $54. The most popular route (Denver Intl - Knoxville McGhee Tyson), is priced around $88.

  • Can I find deals for flights from Denver to Knoxville that include hotel bookings?

    Yes. In addition to deals on Denver to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Knoxville.

  • Can I find deals for business class flights from Denver to Knoxville?

    Yes. Cheapflights offers flight deals from Denver to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Knoxville?

    Currently, February is the cheapest month in which you can book a flight from Denver to Knoxville (average of $57). Flying from Denver to Knoxville in January is currently the most expensive (average of $99). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Denver to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Denver to Nashville flights
Denver to Memphis flights
Denver to Chattanooga flights
Colorado Springs to Nashville flights
Colorado Springs to Memphis flights
Montrose to Nashville flights
Grand Junction to Nashville flights
Colorado Springs to Knoxville flights
Denver to Blountville flights
Durango to Nashville flights
Grand Junction to Blountville flights
Montrose to Knoxville flights
Grand Junction to Knoxville flights
Grand Junction to Chattanooga flights
Aspen to Nashville flights
Gunnison to Knoxville flights
Durango to Knoxville flights
Colorado Springs to Blountville flights
Grand Junction to Memphis flights
Colorado Springs to Chattanooga flights
Aspen to Knoxville flights
Gunnison to Nashville flights
Hayden to Chattanooga flights
Aspen to Memphis flights

Top 5 airlines flying from Denver to Knoxville

Discover the top 5 airlines that operate flights from Denver to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$63Average$131FlexibilityNo cancel feeOn-time88%
FrontierCheapest$83Average$189FlexibilityNo cancel feeOn-time62%
DeltaCheapest$133Average$273FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$218Average$330FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$233Average$438FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.