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$42+ Cheap flights from Denver to Knoxville (DEN - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — TYS
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheapflights Tip: The best prices from Denver Intl to Knoxville McGhee Tyson are usually found in August or April, booked 54 days in advance, depart on a Thursday or Sunday and return on a Thursday

Cheap flight deals from Denver to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$101
(Cheapflightsfares)

One-way from

$42
(Frontier)

Popular in

March

Cheapest in

August

Average price

$226

Good round-trip deal

$133 or less

Good one-way deal

$106 or less
From Denver Intl to Knoxville McGhee Tyson
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One-way flight from Denver Intl to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 2% potential increase in price ($5 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Denver Intl to Knoxville McGhee Tyson.
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Price to beat on a one-way flight from Denver Intl to Knoxville McGhee Tyson.
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Find flight deals from Denver to Knoxville

Cheapest flights from Denver to Knoxville
Explore the most affordable flight options available from Denver to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/69:05 amDEN - TYS
Nonstop2h 39mAllegiant Air
Sun 11/97:00 amTYS - DEN
Nonstop3h 15mAllegiant Air
Deal found 9/16$101
This FlightHub deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:33 amDEN - TYS
Nonstop2h 38mMultiple Airlines
Mon 12/84:47 pmTYS - DEN
Nonstop3h 31mMultiple Airlines
Deal found 9/17$114
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/61:36 pmDEN - TYS
Nonstop2h 46mMultiple Airlines
Sun 11/97:00 amTYS - DEN
Nonstop3h 15mMultiple Airlines
Deal found 9/15$119
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/28:54 amDEN - TYS
Nonstop2h 39mMultiple Airlines
Thu 10/98:17 pmTYS - DEN
Nonstop3h 22mMultiple Airlines
Deal found 9/15$124
This Booking.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/131:36 pmDEN - TYS
Nonstop2h 46mMultiple Airlines
Sun 11/167:00 amTYS - DEN
Nonstop3h 15mMultiple Airlines
Deal found 9/16$131
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/511:29 amDEN - TYS
Nonstop2h 49mFrontier
Thu 10/98:17 pmTYS - DEN
Nonstop3h 22mFrontier
Deal found 9/15$132
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/62:59 pmDEN - TYS
Nonstop2h 46mFrontier
Thu 10/98:17 pmTYS - DEN
Nonstop3h 22mFrontier
Deal found 9/15$140
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/511:29 amDEN - TYS
Nonstop2h 49mFrontier
Mon 10/68:35 pmTYS - DEN
Nonstop3h 09mFrontier
Deal found 9/16$144
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2111:29 amDEN - TYS
Nonstop2h 49mMultiple Airlines
Thu 9/257:00 amTYS - DEN
Nonstop3h 06mMultiple Airlines
Deal found 9/15$145
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/253:03 pmDEN - TYS
Nonstop2h 47mFrontier
Mon 9/298:35 pmTYS - DEN
Nonstop3h 09mFrontier
Deal found 9/16$154

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Denver to Knoxville that are best for you.

Fly from

Denver

Fly to

Knoxville

Route

Depart

Return

Price

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sat 10/4

1:26 pm-11:43 pm

1 stop8h 17m

Knoxville McGhee Tyson

Tue 10/7

4:40 pm-5:53 pm

Nonstop3h 13m

$254

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 10/3

12:59 am-10:25 am

1 stop7h 26m

Knoxville McGhee Tyson

Tue 10/7

2:55 pm-8:15 pm

1 stop7h 20m

$264

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Wed 10/15

6:45 am-4:38 pm

1 stop7h 53m

Knoxville McGhee Tyson

Wed 10/22

5:16 pm-9:41 pm

1 stop6h 25m

$267

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Tue 10/14

5:25 pm-10:28 pm

Nonstop3h 03m

Knoxville McGhee Tyson

Tue 10/21

4:40 pm-5:53 pm

Nonstop3h 13m

$279

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Mon 10/13

12:55 am-11:04 am

1 stop8h 09m

Knoxville McGhee Tyson

Fri 10/17

8:10 pm-11:59 pm

1 stop5h 49m

$299

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Mon 10/6

2:45 pm-10:50 pm

1 stop6h 05m

Knoxville McGhee Tyson

Sat 10/11

4:40 pm-5:53 pm

Nonstop3h 13m

$308

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 10/31

4:05 pm-11:59 pm

1 stop5h 54m

Knoxville McGhee Tyson

Tue 11/4

4:58 pm-6:25 pm

Nonstop3h 27m

$319

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Wed 10/8

5:25 pm-10:28 pm

Nonstop3h 03m

Knoxville McGhee Tyson

Wed 10/15

7:00 am-10:35 am

1 stop5h 35m

$324

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 10/3

5:25 pm-10:28 pm

Nonstop3h 03m

Knoxville McGhee Tyson

Fri 10/10

4:40 pm-5:53 pm

Nonstop3h 13m

$324

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Wed 11/26

6:00 am-1:17 pm

1 stop5h 17m

Knoxville McGhee Tyson

Sun 11/30

2:25 pm-7:29 pm

1 stop7h 04m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Showing 1-10 of 21 results
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Best time to book a flight from Denver to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Knoxville

How far ahead should I book a flight from Denver to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Denver to Knoxville. Price data was last updated on September 12, 2025.

The price you pay for your flight from Denver to Knoxville may vary depending on when you book. For the best chance of a lower fare, look to book 54 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Denver to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Denver to Knoxville (average of $295). Flying from Denver to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to TYS?

Find hourly flight availability from Denver to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

It’s typically best to fly out from Denver to Knoxville at noon. Doing so could potentially save you 44% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Denver to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Denver to Knoxville. Price data was last updated on September 14, 2025.

Travelers seeking maximum savings on their Denver to Knoxville flight should consider departing on Wednesday at noon when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 17, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Denver to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Allegiant Air
7.2
Good
699 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Frontier
5.8
Fair
3,173 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Denver to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Denver to Knoxville?

    Booking a flight from Denver Intl (DEN) to Knoxville McGhee Tyson (TYS) is your only option if you wish to fly from Denver to Knoxville. On a typical day, there is 1 flight from Denver Intl to McGhee Tyson, all of which are around 2h 38m for a nonstop flight. You can also purchase a plane ticket from 5 airlines when you book a flight from Denver Intl to Knoxville.

  • How popular is this Denver to Knoxville flight route?

    Within the past month, 1 users have taken a look at flights from Denver Intl to Knoxville McGhee Tyson.

  • How long is the flight from Denver to Knoxville?

    United Airlines and Delta can get you from Denver to Knoxville in just under 7h 26m. Your travel time can differ by up to 51m. Denver and Knoxville are separated by a distance of 1159 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Denver to Knoxville round-trip?

    Our cheapest airline available from Denver to Knoxville is Allegiant Air. Our recent data shows that you can find tickets from as low as $70 on this airline. Additional options worth looking into are Frontier and Delta, starting at $78 and $197 round-trip. These flights start at 72% lower than the current average price 3 months from now.

  • What are the most reliable airlines from Denver to Knoxville?

    The top 3 most reliable airlines when flying from Denver to Knoxville are Frontier (67%), United Airlines (64%) and Allegiant Air (55%).

  • What are the cheapest flights from Denver to Knoxville?

    Looking for the cheapest flight from Denver to Knoxville? While on average our users pay $206, our data indicates the cheapest price to be $50. The most popular route (Denver Intl - Knoxville McGhee Tyson), is priced around $101.

  • Can I find deals for flights from Denver to Knoxville that include hotel bookings?

    Yes. In addition to deals on Denver to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Knoxville.

  • Can I find deals for business class flights from Denver to Knoxville?

    Yes. Cheapflights offers flight deals from Denver to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Denver to Knoxville (average of $295). Flying from Denver to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Alternative routes for Denver to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Denver to Knoxville

Discover the top 5 airlines that operate flights from Denver to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$70Average$134FlexibilityNo cancel feeOn-time88%
FrontierCheapest$78Average$174FlexibilityNo cancel feeOn-time62%
DeltaCheapest$197Average$277FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$218Average$331FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$233Average$458FlexibilityNo cancel feeOn-time69%

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