$52+ Cheap flights from Colorado to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — TYS
Oct 17 — Oct 241
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Colorado to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Colorado to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Colorado to KnoxvilleExplore the most affordable flight options available from Colorado to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Colorado to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:30 am -
Nonstop2h 49m
Sun 11/156:30 am -
Nonstop3h 10m
Deal found 9/14![Allegiant Air logo]()
$135
This CheapOair deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:26 am -
Nonstop2h 45m
Thu 11/56:30 am -
Nonstop3h 10m
Deal found 9/13![Allegiant Air logo]()
$147
This CheapOair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:26 am -
Nonstop2h 45m
Sun 11/16:30 am -
Nonstop3h 06m
Deal found 9/16![Allegiant Air logo]()
$157
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:15 am -
Nonstop2h 37m
Sun 11/226:20 am -
Nonstop3h 25m
Deal found 9/13![Allegiant Air logo]()
$161
This CheapOair deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:30 am -
Nonstop2h 49m
Sun 11/86:30 am -
Nonstop3h 10m
Deal found 9/13![Allegiant Air logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:26 am -
Nonstop2h 45m
Thu 11/56:33 pm -
2 stops39h 49m
Deal found 9/15![Multiple Airlines logo]()
$190
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:25 am -
1 stop7h 35m
Wed 11/44:15 pm -
1 stop7h 30m
Deal found 9/14![Southwest logo]()
$255
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:55 am -
1 stop6h 35m
Fri 11/135:25 pm -
1 stop6h 25m
Deal found 9/17![Southwest logo]()
$272
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:00 am -
2 stops11h 49m
Wed 11/411:45 am -
2 stops10h 31m
Deal found 9/14![Delta logo]()
$283
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:31 pm -
1 stop4h 37m
Fri 10/232:38 pm -
1 stop7h 38m
Deal found 9/17![Delta logo]()
$291
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:00 am -
1 stop5h 40m
Thu 10/2212:06 pm -
2 stops12h 16m
Deal found 9/17![Delta logo]()
$296
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:58 pm -
1 stop5h 20m
Tue 10/276:00 am -
1 stop5h 37m
Deal found 9/15![American Airlines logo]()
$299
Best flights from Colorado to KnoxvilleDiscover carefully curated flight deals from Colorado to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Colorado to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1212:59 am -
1 stop6h 35m
Tue 10/2012:06 pm -
1 stop5h 07m
Deal found 9/15![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:55 am -
2 stops10h 55m
Mon 11/93:40 pm -
1 stop8h 05m
Deal found 9/13![Southwest logo]()
$332
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/27:00 am -
1 stop5h 36m
Wed 2/34:25 pm -
1 stop6h 31m
Deal found 9/15![United Airlines logo]()
$347
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:34 pm -
1 stop21h 37m
Tue 10/66:04 pm -
2 stops28h 59m
Deal found 9/12![Multiple Airlines logo]()
$396
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:14 pm -
1 stop8h 04m
Mon 10/266:00 am -
1 stop8h 23m
Deal found 9/17![American Airlines logo]()
$467
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:37 pm -
1 stop6h 37m
Wed 10/289:00 am -
1 stop5h 33m
Deal found 9/14![United Airlines logo]()
$348
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop6h 40m
Sat 10/317:26 am -
2 stops12h 06m
Deal found 9/16![Delta logo]()
$384
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
1 stop5h 40m
Wed 10/2811:45 am -
2 stops10h 31m
Deal found 9/13![Delta logo]()
$394
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1310:45 am -
2 stops7h 55m
Sat 2/206:35 am -
2 stops9h 20m
Deal found 9/13![Southwest logo]()
$447
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:42 pm -
Nonstop2h 50m
Fri 10/309:00 am -
Nonstop3h 28m
Deal found 9/16![United Airlines logo]()
$410
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/812:51 pm -
1 stop6h 08m
Mon 1/117:00 am -
1 stop6h 51m
Deal found 9/16![United Airlines logo]()
$437
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:01 pm -
2 stops9h 21m
Sat 10/35:35 pm -
1 stop6h 22m
Deal found 9/17![American Airlines logo]()
$534
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:35 pm -
1 stop6h 57m
Wed 11/189:00 am -
1 stop5h 33m
Deal found 9/13![United Airlines logo]()
$438
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:01 pm -
2 stops9h 21m
Sat 10/35:35 pm -
1 stop6h 22m
Deal found 9/15![American Airlines logo]()
$554
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:10 am -
1 stop6h 54m
Tue 11/109:00 am -
1 stop5h 39m
Deal found 9/15![United Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:34 pm -
1 stop6h 40m
Tue 10/64:53 pm -
1 stop7h 13m
Deal found 9/17![United Airlines logo]()
$464
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/135:43 pm -
Nonstop3h 07m
Wed 12/164:43 pm -
Nonstop3h 27m
Deal found 9/14![United Airlines logo]()
$468
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/171:34 pm -
1 stop6h 40m
Thu 10/299:00 am -
1 stop5h 45m
Deal found 9/14![United Airlines logo]()
$477
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am -
1 stop6h 42m
Sat 10/179:00 am -
Nonstop3h 18m
Deal found 9/12![United Airlines logo]()
$481
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:25 pm -
Nonstop2h 49m
Mon 10/54:53 pm -
Nonstop3h 21m
Deal found 9/15![United Airlines logo]()
$504
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop5h 13m
Thu 12/34:43 pm -
Nonstop3h 27m
Deal found 9/13![United Airlines logo]()
$507
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am -
1 stop5h 14m
Tue 10/69:00 am -
Nonstop3h 18m
Deal found 9/15![United Airlines logo]()
$508
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:25 pm -
Nonstop2h 49m
Mon 10/54:53 pm -
Nonstop3h 21m
Deal found 9/12![United Airlines logo]()
$518
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:00 am -
2 stops11h 49m
Sat 10/33:45 pm -
2 stops8h 21m
Deal found 9/16![United Airlines logo]()
$600
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:15 pm -
1 stop6h 34m
Sat 10/247:15 am -
1 stop6h 47m
Deal found 9/12![United Airlines logo]()
$648
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/309:24 am -
2 stops12h 35m
Sat 10/312:05 pm -
2 stops10h 25m
Deal found 9/15![United Airlines logo]()
$676
Last-minute flights from Colorado to KnoxvilleDiscover last-minute flight deals from Colorado to Knoxville. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Colorado to Knoxville. Data last updated September 17, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:26 am -
Nonstop2h 45m
Thu 10/86:30 am -
Nonstop3h 06m
Deal found 9/17![Allegiant Air logo]()
$223
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:31 pm -
1 stop4h 37m
Fri 10/232:38 pm -
1 stop7h 38m
Deal found 9/17![Delta logo]()
$291
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:29 pm -
1 stop6h 45m
Tue 10/276:45 am -
2 stops7h 36m
Deal found 9/17![United Airlines logo]()
$296
This CheapOair deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:26 am -
Nonstop2h 45m
Thu 10/296:30 am -
Nonstop3h 06m
Deal found 9/13![Allegiant Air logo]()
$222
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:58 pm -
1 stop5h 20m
Tue 10/276:00 am -
1 stop5h 37m
Deal found 9/15![American Airlines logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:42 pm -
2 stops13h 02m
Sun 11/16:30 am -
Nonstop3h 06m
Deal found 9/15![Multiple Airlines logo]()
$241
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:55 am -
Nonstop2h 45m
Tue 11/34:15 pm -
Nonstop3h 20m
Deal found 9/14![Southwest logo]()
$251
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:15 am -
Nonstop2h 46m
Tue 11/37:35 pm -
1 stop6h 44m
Deal found 9/15![United Airlines logo]()
$248
This CheapOair deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:26 am -
Nonstop2h 45m
Thu 11/56:30 am -
Nonstop3h 10m
Deal found 9/13![Allegiant Air logo]()
$147
This CheapOair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:26 am -
Nonstop2h 45m
Sun 11/16:30 am -
Nonstop3h 06m
Deal found 9/16![Allegiant Air logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:26 am -
Nonstop2h 45m
Mon 11/22:12 pm -
2 stops33h 20m
Deal found 9/15![Multiple Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:55 pm -
1 stop17h 56m
Thu 11/56:30 am -
Nonstop3h 10m
Deal found 9/13![Multiple Airlines logo]()
$243
One-way flights from Colorado to KnoxvilleSearch for one-way flight options from Colorado to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Colorado to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:30 am -
Nonstop2h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Allegiant Air logo]()
$52
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:30 am -
Nonstop2h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Allegiant Air logo]()
$55
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:26 am -
Nonstop2h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Allegiant Air logo]()
$56
This CheapOair deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:15 am -
Nonstop2h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Allegiant Air logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:26 am -
Nonstop2h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Allegiant Air logo]()
$96
This CheapOair deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:30 am -
Nonstop2h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Allegiant Air logo]()
$109
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop6h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Delta logo]()
$242
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:55 am -
2 stops10h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Southwest logo]()
$247
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:37 pm -
1 stop6h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![United Airlines logo]()
$258
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/32:55 pm -
1 stop5h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![United Airlines logo]()
$287
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:00 am -
1 stop5h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Southwest logo]()
$294
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:58 pm -
1 stop5h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$296
Find flight deals from Colorado to Knoxville
Keep the following information in mind while searching for Colorado to Knoxville flight deals. Data was last updated September 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $135 (Cheapflightsfares) |
One-way from | $52 (Kiwi.com) |
Popular in | March |
Cheapest in | November |
Average price | $349 |
Good round-trip deal | $294 or less |
Good one-way deal | $138 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Colorado to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Colorado to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Sat 2/20
11:50 pm-10:00 am
1 stop8h 10m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$124
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Mon 10/12
12:59 am-9:34 am
1 stop6h 35m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$135
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Tue 12/15
6:00 am-1:50 pm
1 stop5h 50m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$146
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Wed 11/11
5:42 pm-10:32 pm
Nonstop2h 50m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$170
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Tue 10/13
11:52 pm-10:37 am
1 stop8h 45m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$180
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Mon 11/2
5:42 pm-10:32 pm
Nonstop2h 50m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$196
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Fri 11/13
5:42 pm-10:32 pm
Nonstop2h 50m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$215
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Sun 11/22
12:20 pm-8:35 pm
2 stops6h 15m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$224
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Thu 12/10
8:20 am-7:45 pm
2 stops9h 25m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$224
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Mon 3/15
2:20 pm-9:37 pm
1 stop5h 17m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$240
Showing 1-10 of 46 resultsSorted by cheapest first
Best time to book a flight from Colorado to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Colorado with our price prediction graph.
DEN-TYS
COS-TYS
MTJ-TYS
DRO-TYS
GJT-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Colorado to Knoxville
USCO-TYS
DEN-TYS
COS-TYS
MTJ-TYS
DRO-TYS
What is the cheapest month to book a flight from Colorado to Knoxville?
Currently, November is the cheapest month in which you can book a flight from Colorado to Knoxville (average of $200). Flying from Colorado to Knoxville in July is currently the most expensive (average of $385). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CO to TYS?
Find hourly flight availability from Colorado to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2026.
When flying from Colorado to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Weekly flight availability from Colorado to Knoxville
Explore weekly flight availability from Colorado to Knoxville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 17, 2026.
The most flights from USCO to TYS are scheduled on a Tuesday (3 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Colorado to Knoxville?
Airfare is below average for this route at the moment.
Colorado to Knoxville flights typically cost between $228 and $447 in November.The cheapest round-trip price found within the last 5 days was $135 on Allegiant Air (Nov 12-Nov 15).
How far ahead should I book a flight from Colorado to Knoxville?
To ensure you get the cheapest price possible for a flight from Colorado to Knoxville, you should look to book at least 49 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Related info for your journey
Find useful and relevant information for your journey from Colorado to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Knoxville flight routes
Other flight options
Popular flights
Top destinations
Alternative routes for Colorado to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Colorado to Knoxville by cabin class
Find flights from Colorado to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 17, 2026.
Colorado and Knoxville flights
Browse other Colorado and Knoxville flight options. Last updated on September 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Colorado to Knoxville flights
Consider these flights traveling from Colorado to Knoxville.
Top 6 airlines flying from Colorado to Knoxville
Discover the top 6 airlines that operate flights from Colorado to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$62 | Average$155 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$84 | Average$228 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$124 | Average$348 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$204 | Average$479 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$401 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$249 | Average$437 | FlexibilityNo cancel fee | On-time63% |