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Knoxville

$58+ Cheap flights from Colorado to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — TYS
Aug 27 — Sep 31
Thu 8/27
Thu 9/3
1 adult, Economy
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Cheap flight deals from Colorado to Knoxville

Cheapest flights from Colorado to Knoxville
Explore the most affordable flight options available from Colorado to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.

This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:00 am
DEN
-
TYS
Nonstop2h 49m
Allegiant Air
Sun 8/307:00 am
TYS
-
DEN
Nonstop3h 10m
Allegiant Air
Deal found 7/22$142
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:30 am
DEN
-
TYS
Nonstop2h 49m
Allegiant Air
Thu 11/198:00 am
TYS
-
DEN
Nonstop3h 25m
Allegiant Air
Deal found 7/25$145
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:40 pm
DEN
-
TYS
1 stop23h 03m
Multiple Airlines
Sun 8/237:00 am
TYS
-
DEN
Nonstop3h 10m
Multiple Airlines
Deal found 7/25$148
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:00 am
DEN
-
TYS
Nonstop2h 49m
Allegiant Air
Thu 8/277:00 am
TYS
-
DEN
Nonstop3h 10m
Allegiant Air
Deal found 7/22$150
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/108:55 am
DEN
-
TYS
Nonstop2h 49m
Allegiant Air
Sun 9/137:00 am
TYS
-
DEN
Nonstop3h 05m
Allegiant Air
Deal found 7/26$151
This CheapOair deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:11 am
DEN
-
TYS
Nonstop2h 50m
Allegiant Air
Sun 8/97:00 am
TYS
-
DEN
Nonstop3h 21m
Allegiant Air
Deal found 7/23$160
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:26 pm
DEN
-
TYS
1 stop15h 35m
Multiple Airlines
Sun 8/307:00 am
TYS
-
DEN
Nonstop3h 10m
Multiple Airlines
Deal found 7/22$161
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/172:34 pm
DEN
-
TYS
Nonstop2h 50m
Multiple Airlines
Sun 8/237:00 am
TYS
-
DEN
Nonstop3h 10m
Multiple Airlines
Deal found 7/23$162
This Cheapflightsfares deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/278:55 am
DEN
-
TYS
Nonstop2h 49m
Allegiant Air
Thu 10/16:30 am
TYS
-
DEN
Nonstop3h 06m
Allegiant Air
Deal found 7/24$163
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:51 pm
COS
-
TYS
1 stop5h 27m
American Airlines
Tue 9/156:00 am
TYS
-
COS
1 stop8h 05m
American Airlines
Deal found 7/25$310
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:45 am
COS
-
TYS
1 stop6h 08m
American Airlines
Mon 9/145:35 pm
TYS
-
COS
1 stop7h 20m
American Airlines
Deal found 7/27$322
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:15 am
COS
-
TYS
1 stop6h 30m
Southwest
Wed 11/182:45 pm
TYS
-
COS
2 stops9h 05m
Southwest
Deal found 7/26$327

Find flight deals from Colorado to Knoxville

Keep the following information in mind while searching for Colorado to Knoxville flight deals. Data was last updated July 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$145
(Kiwi.com)

One-way from

$58
(CheapOair)

Popular in

March

Cheapest in

August

Average price

$357

Good round-trip deal

$149 or less

Good one-way deal

$146 or less
Provider with most accurate pricing for Denver Intl-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Knoxville McGhee Tyson flights.
Search Deals
From Colorado to Knoxville McGhee Tyson
Search Deals
One-way flight from Colorado to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($50 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals
Price to beat on a round-trip flight from Colorado to Knoxville McGhee Tyson.
Search Deals
Price to beat on a one-way flight from Colorado to Knoxville McGhee Tyson.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Colorado to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
Use the filters below to find and compare flights from Colorado to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Tue 8/25

7:45 am-4:58 pm

1 stop7h 13m

Knoxville McGhee Tyson

Sat 8/29

4:50 pm-6:10 pm

Nonstop3h 20m

$293

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 9/4

12:59 am-10:16 am

1 stop7h 17m

Knoxville McGhee Tyson

Sat 9/5

5:00 pm-11:02 pm

1 stop8h 02m

$309

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Tue 9/8

3:51 pm-11:18 pm

1 stop5h 27m

Knoxville McGhee Tyson

Sat 9/12

6:00 am-9:22 am

1 stop5h 22m

$311

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Sat 10/3

5:45 am-2:29 pm

1 stop6h 44m

Knoxville McGhee Tyson

Sat 10/31

6:56 am-3:00 pm

2 stops10h 04m

$316

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Thu 11/12

6:00 am-3:18 pm

1 stop7h 18m

Knoxville McGhee Tyson

Wed 11/18

2:40 pm-8:27 pm

1 stop7h 47m

$322

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Thu 11/12

10:15 am-6:45 pm

1 stop6h 30m

Knoxville McGhee Tyson

Wed 11/18

2:45 pm-9:50 pm

2 stops9h 05m

$327

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Thu 9/10

1:25 pm-8:15 pm

1 stop4h 50m

Knoxville McGhee Tyson

Sun 9/13

4:40 pm-7:56 pm

1 stop5h 16m

$337

Grand JunctionKnoxville

GJT - TYS

GJTTYS

Grand Junction Regnl

Sat 8/22

1:40 pm-10:29 pm

1 stop6h 49m

Knoxville McGhee Tyson

Sat 8/29

9:00 am-2:37 pm

1 stop7h 37m

$339

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 10/2

1:15 pm-9:50 pm

1 stop6h 35m

Knoxville McGhee Tyson

Tue 10/6

12:06 pm-5:49 pm

1 stop7h 43m

$350

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 9/3

5:00 am-12:35 pm

1 stop5h 35m

Knoxville McGhee Tyson

Sun 9/6

8:55 am-2:30 pm

2 stops7h 35m

$358

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/26

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Colorado to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Knoxville

What is the cheapest month to book a flight from Colorado to Knoxville?

Currently, November is the cheapest month in which you can book a flight from Colorado to Knoxville (average of $214). Flying from Colorado to Knoxville in March is currently the most expensive (average of $380). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to TYS?

Find hourly flight availability from Colorado to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 28, 2026.

When flying from Colorado to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Colorado to Knoxville

Explore weekly flight availability from Colorado to Knoxville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 28, 2026.

The most flights from USCO to TYS are scheduled on a Monday (5 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (2 on average).

How much does it cost to fly round-trip from Colorado to Knoxville?

Airfare is typical for this route at the moment.
Colorado to Knoxville flights typically cost between $114 and $316 in November.
The cheapest round-trip price found within the last 5 days was $145 on Allegiant Air (Nov 15-Nov 19).

How far ahead should I book a flight from Colorado to Knoxville?

To ensure you get the cheapest price possible for a flight from Colorado to Knoxville, you should look to book at least 49 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

Related info for your journey

Find useful and relevant information for your journey from Colorado to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Colorado?

    For a flight from Colorado to Knoxville, you will be flying into McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • How popular is this Colorado to Knoxville flight route?

    The Colorado to Knoxville McGhee Tyson flight path was viewed by 24 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Colorado to Knoxville?

    There are many flights that can get you from Colorado to Knoxville in 5h 27m. Fly via United Airlines, Delta, or American Airlines to get the fastest option. The distance from Colorado to Knoxville is about 1153 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Colorado to Knoxville one-way?

    One-way options have recently been found by users for as low as $54 on Frontier. Other airlines that offer cheap prices include Allegiant Air from $58 and Delta from $124 one-way.

  • What are the most popular routes from Colorado to Knoxville?

    Most travelers choose Denver Intl - Knoxville McGhee Tyson, Colorado Springs - Knoxville McGhee Tyson or Durango La Plata County - Knoxville McGhee Tyson when deciding on the best route from Colorado to Knoxville.

  • What are the most reliable airlines from Colorado to Knoxville?

    Before booking your flight to Knoxville from Colorado, check out the most reliable airlines to get you to your destination on time: Allegiant Air (98%), Frontier (86%), Volaris( 86%).

  • What are the cheapest flights from Colorado to Knoxville?

    Looking for the cheapest flight from Colorado to Knoxville? While on average our users pay $250, our data indicates the cheapest price to be $57. The most popular route (Denver Intl - Knoxville McGhee Tyson), is priced around $111.

  • Can I find deals for flights from Colorado to Knoxville that include hotel bookings?

    Yes. In addition to deals on Colorado to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Knoxville.

  • Can I find deals for business class flights from Colorado to Knoxville?

    Yes. Cheapflights offers flight deals from Colorado to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to Knoxville?

    Currently, November is the cheapest month in which you can book a flight from Colorado to Knoxville (average of $214). Flying from Colorado to Knoxville in March is currently the most expensive (average of $380). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa

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Alternative routes for Colorado to Knoxville

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Top 6 airlines flying from Colorado to Knoxville

Discover the top 6 airlines that operate flights from Colorado to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$58Average$148FlexibilityNo cancel feeOn-time88%
FrontierCheapest$84Average$227FlexibilityNo cancel feeOn-time62%
DeltaCheapest$124Average$347FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$204Average$461FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$224Average$396FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$248Average$393FlexibilityNo cancel feeOn-time63%

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