$80+ Cheap flights from Colorado to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — TYS
Dec 5 — Dec 121
Round-trip
1 adult, Economy
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Find cheap flights from Colorado to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Colorado to Knoxville
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Cheapest flights from Colorado to KnoxvilleExplore the most affordable flight options available from Colorado to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
Explore the most affordable flight options available from Colorado to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:30 am -
Nonstop2h 49m
Thu 11/198:00 am -
Nonstop3h 25m
Deal found 11/1![Allegiant Air logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:30 am -
Nonstop2h 49m
Sun 11/156:30 am -
Nonstop3h 10m
Deal found 11/1![Allegiant Air logo]()
$180
This Cheapflightsfares deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:30 am -
Nonstop2h 49m
Sun 11/156:30 am -
Nonstop3h 10m
Deal found 11/4![Allegiant Air logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:30 am -
Nonstop2h 49m
Thu 11/198:00 am -
Nonstop3h 25m
Deal found 11/1![Allegiant Air logo]()
$245
This CheapOair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:15 am -
Nonstop2h 37m
Sun 11/226:20 am -
Nonstop3h 25m
Deal found 11/5![Allegiant Air logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:30 am -
Nonstop2h 49m
Thu 11/1911:36 am -
2 stops30h 10m
Deal found 11/1![Multiple Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:19 pm -
1 stop18h 57m
Mon 12/78:00 am -
1 stop14h 00m
Deal found 11/4![Multiple Airlines logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:30 am -
Nonstop2h 49m
Mon 11/168:30 am -
1 stop15h 18m
Deal found 11/1![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:10 am -
2 stops30h 06m
Mon 12/148:00 am -
1 stop14h 00m
Deal found 11/2![Multiple Airlines logo]()
$304
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/231:20 pm -
1 stop7h 12m
Wed 12/25:00 pm -
1 stop6h 37m
Deal found 11/1![United Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/91:30 pm -
1 stop7h 20m
Thu 12/176:21 am -
1 stop9h 59m
Deal found 11/2![United Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:20 pm -
1 stop7h 12m
Wed 12/24:43 pm -
1 stop6h 06m
Deal found 10/31![United Airlines logo]()
$380
Best flights from Colorado to KnoxvilleDiscover carefully curated flight deals from Colorado to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
Discover carefully curated flight deals from Colorado to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:46 am -
1 stop6h 48m
Tue 12/811:49 am -
1 stop7h 25m
Deal found 10/31![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/127:15 am -
1 stop5h 40m
Sat 1/169:45 am -
1 stop7h 19m
Deal found 11/5![United Airlines logo]()
$347
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:10 pm -
Nonstop2h 35m
Sun 12/138:10 am -
2 stops7h 50m
Deal found 11/3![Southwest logo]()
$366
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/241:27 pm -
1 stop6h 06m
Thu 12/314:27 pm -
2 stops9h 13m
Deal found 11/4![American Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/91:30 pm -
2 stops8h 29m
Thu 12/176:00 am -
1 stop7h 51m
Deal found 11/2![United Airlines logo]()
$352
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/76:00 am -
2 stops9h 27m
Sat 4/108:47 am -
1 stop6h 11m
Deal found 11/4![Delta logo]()
$366
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:20 am -
2 stops9h 30m
Tue 12/87:05 am -
2 stops8h 40m
Deal found 11/1![Southwest logo]()
$398
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:20 pm -
2 stops8h 39m
Wed 12/24:43 pm -
1 stop5h 27m
Deal found 10/31![United Airlines logo]()
$410
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1110:15 am -
1 stop6h 30m
Sun 12/135:25 pm -
1 stop6h 25m
Deal found 11/3![Southwest logo]()
$440
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:55 am -
Nonstop2h 46m
Tue 12/84:43 pm -
Nonstop3h 27m
Deal found 10/31![United Airlines logo]()
$429
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:50 am -
2 stops10h 00m
Thu 12/317:05 am -
2 stops10h 30m
Deal found 11/3![Southwest logo]()
$449
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/25:47 am -
1 stop5h 33m
Wed 2/35:55 pm -
1 stop6h 04m
Deal found 10/31![United Airlines logo]()
$457
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2412:40 pm -
2 stops8h 00m
Tue 12/17:55 am -
2 stops11h 10m
Deal found 10/31![Southwest logo]()
$468
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1412:10 pm -
1 stop7h 47m
Tue 12/154:43 pm -
1 stop6h 06m
Deal found 11/1![United Airlines logo]()
$457
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2011:08 am -
1 stop10h 03m
Tue 12/15:40 am -
1 stop6h 00m
Deal found 11/1![Delta logo]()
$612
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/812:39 pm -
1 stop6h 26m
Mon 1/116:01 am -
1 stop7h 52m
Deal found 11/2![United Airlines logo]()
$457
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/287:05 am -
1 stop5h 50m
Mon 2/19:45 am -
2 stops12h 48m
Deal found 11/3![United Airlines logo]()
$462
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/109:55 am -
Nonstop2h 45m
Mon 1/44:55 pm -
Nonstop3h 30m
Deal found 11/2![United Airlines logo]()
$488
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/97:00 am -
1 stop5h 56m
Tue 1/124:28 pm -
1 stop6h 11m
Deal found 11/1![United Airlines logo]()
$489
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/237:00 am -
1 stop5h 56m
Wed 1/274:28 pm -
1 stop6h 11m
Deal found 11/3![United Airlines logo]()
$489
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:45 pm -
2 stops25h 59m
Thu 12/315:57 pm -
1 stop7h 23m
Deal found 11/2![United Airlines logo]()
$536
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/81:33 pm -
1 stop6h 24m
Sat 12/124:43 pm -
1 stop6h 44m
Deal found 11/2![United Airlines logo]()
$644
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2611:35 am -
1 stop8h 22m
Sat 11/289:00 am -
Nonstop3h 28m
Deal found 11/1![United Airlines logo]()
$693
Last-minute flights from Colorado to KnoxvilleDiscover last-minute flight deals from Colorado to Knoxville. Data last updated November 5, 2026 and is based on user searches.
Discover last-minute flight deals from Colorado to Knoxville. Data last updated November 5, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:30 am -
Nonstop2h 49m
Thu 11/198:00 am -
Nonstop3h 25m
Deal found 11/1![Allegiant Air logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:30 am -
Nonstop2h 49m
Sun 11/156:30 am -
Nonstop3h 10m
Deal found 11/1![Allegiant Air logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:30 am -
Nonstop2h 49m
Thu 11/1911:36 am -
2 stops30h 10m
Deal found 11/1![Multiple Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:30 am -
Nonstop2h 49m
Mon 11/168:30 am -
1 stop15h 18m
Deal found 11/1![Multiple Airlines logo]()
$279
This Cheapflightsfares deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:30 am -
Nonstop2h 49m
Sun 11/156:30 am -
Nonstop3h 10m
Deal found 11/4![Allegiant Air logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:30 am -
Nonstop2h 49m
Thu 11/198:00 am -
Nonstop3h 25m
Deal found 11/1![Allegiant Air logo]()
$245
This CheapOair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:15 am -
Nonstop2h 37m
Sun 11/226:20 am -
Nonstop3h 25m
Deal found 11/5![Allegiant Air logo]()
$258
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/231:20 pm -
1 stop7h 12m
Wed 12/25:00 pm -
1 stop6h 37m
Deal found 11/1![United Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:20 pm -
1 stop7h 12m
Wed 12/24:43 pm -
1 stop6h 06m
Deal found 10/31![United Airlines logo]()
$380
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:19 pm -
1 stop18h 57m
Mon 12/78:00 am -
1 stop14h 00m
Deal found 11/4![Multiple Airlines logo]()
$276
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/91:30 pm -
1 stop7h 20m
Thu 12/176:21 am -
1 stop9h 59m
Deal found 11/2![United Airlines logo]()
$347
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:10 am -
2 stops30h 06m
Mon 12/148:00 am -
1 stop14h 00m
Deal found 11/2![Multiple Airlines logo]()
$304
One-way flights from Colorado to KnoxvilleSearch for one-way flight options from Colorado to Knoxville. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
Search for one-way flight options from Colorado to Knoxville. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
This Super.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:30 am -
Nonstop2h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Allegiant Air logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/67:18 am -
2 stops34h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/59:37 pm -
3 stops39h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$121
This CheapOair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:56 am -
Nonstop2h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Allegiant Air logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:25 am -
1 stop13h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/257:39 am -
1 stop11h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/87:09 pm -
1 stop13h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/73:16 pm -
3 stops25h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$143
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/231:20 pm -
1 stop7h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![United Airlines logo]()
$174
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/11:26 pm -
1 stop7h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![United Airlines logo]()
$174
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/11:40 pm -
1 stop5h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Delta logo]()
$207
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/256:00 am -
1 stop5h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Delta logo]()
$212
Find flight deals from Colorado to Knoxville
Keep the following information in mind while searching for Colorado to Knoxville flight deals. Data was last updated November 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $174 (Kiwi.com) |
One-way from | $80 (Super.com) |
Popular in | March |
Cheapest in | August |
Average price | $355 |
Good round-trip deal | $328 or less |
Good one-way deal | $159 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Colorado to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
Use the filters below to find and compare flights from Colorado to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Thu 1/7
10:10 am-2:55 pm
Nonstop2h 45m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$160
Quickest round-trip
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Fri 1/8
11:15 am-3:55 pm
Nonstop2h 40m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$160
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Mon 11/23
5:42 pm-10:32 pm
Nonstop2h 50m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$160
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Wed 1/6
11:15 am-3:55 pm
Nonstop2h 40m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$160
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Fri 12/4
9:55 am-2:41 pm
Nonstop2h 46m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$160
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Fri 12/4
4:10 pm-11:24 pm
1 stop5h 14m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$170
DenverKnoxville
DEN Denver Intl - TYS Knoxville McGhee Tyson
DENTYS
Denver Intl
Mon 12/21
6:00 am-2:42 pm
1 stop6h 42m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$170
Colorado SpringsKnoxville
COS Colorado Springs - TYS Knoxville McGhee Tyson
COSTYS
Colorado Springs
Mon 11/23
1:20 pm-10:32 pm
1 stop7h 12m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$174
HaydenKnoxville
HDN Hayden Yampa Valley - TYS Knoxville McGhee Tyson
HDNTYS
Hayden Yampa Valley
Tue 12/1
1:26 pm-10:50 pm
1 stop7h 24m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$174
Colorado SpringsKnoxville
COS Colorado Springs - TYS Knoxville McGhee Tyson
COSTYS
Colorado Springs
Thu 4/1
1:40 pm-8:40 pm
1 stop5h 00m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$207
Showing 1-10 of 41 resultsSorted by cheapest first
Best time to book a flight from Colorado to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Colorado with our price prediction graph.
DEN-TYS
COS-TYS
MTJ-TYS
HDN-TYS
GJT-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Colorado to Knoxville
USCO-TYS
DEN-TYS
COS-TYS
MTJ-TYS
HDN-TYS
What is the cheapest month to book a flight from Colorado to Knoxville?
Currently, August is the cheapest month in which you can book a flight from Colorado to Knoxville (average of $230). Flying from Colorado to Knoxville in July is currently the most expensive (average of $387). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CO to TYS?
Find hourly flight availability from Colorado to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 5, 2026.
When flying from Colorado to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Weekly flight availability from Colorado to Knoxville
Explore weekly flight availability from Colorado to Knoxville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 5, 2026.
The most flights from USCO to TYS are scheduled on a Tuesday (3 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Colorado to Knoxville?
Airfare is below average for this route at the moment.
Colorado to Knoxville flights typically cost between $188 and $405 in November.The cheapest round-trip price found within the last 5 days was $174 on Allegiant Air (Nov 8-Nov 19).
How far ahead should I book a flight from Colorado to Knoxville?
To ensure you get the cheapest price possible for a flight from Colorado to Knoxville, you should look to book at least 89 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Related info for your journey
Find useful and relevant information for your journey from Colorado to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Morristown
Newport
Bryson City
Crossville
Murphy
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Colorado to Knoxville
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Complete your trip
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Search flights from Colorado to Knoxville by cabin class
Find flights from Colorado to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 5, 2026.
Colorado and Knoxville flights
Browse other Colorado and Knoxville flight options. Last updated on November 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Colorado to Knoxville flights
Consider these flights traveling from Colorado to Knoxville.
Top 6 airlines flying from Colorado to Knoxville
Discover the top 6 airlines that operate flights from Colorado to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$69 | Average$167 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$84 | Average$243 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$124 | Average$326 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$204 | Average$504 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$231 | Average$454 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$268 | Average$431 | FlexibilityNo cancel fee | On-time63% |