HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$61+ Cheap flights from Colorado to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — TYS
Jul 13 — Jul 201
Mon 7/13
Mon 7/20
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Colorado to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Colorado to Knoxville

Cheapest flights from Colorado to Knoxville
Explore the most affordable flight options available from Colorado to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 13, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:55 am
DEN
-
TYS
Nonstop2h 49m
Allegiant Air
Thu 9/247:00 am
TYS
-
DEN
Nonstop3h 05m
Allegiant Air
Deal found 6/9$123
This CheapOair deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/239:01 am
DEN
-
TYS
Nonstop2h 50m
Allegiant Air
Sun 7/267:00 am
TYS
-
DEN
Nonstop3h 11m
Allegiant Air
Deal found 6/10$130
This Cheapflightsfares deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:55 am
DEN
-
TYS
Nonstop2h 49m
Allegiant Air
Sun 9/207:00 am
TYS
-
DEN
Nonstop3h 05m
Allegiant Air
Deal found 6/11$135
This Cheapflightsfares deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:55 am
DEN
-
TYS
Nonstop2h 49m
Allegiant Air
Sun 9/277:00 am
TYS
-
DEN
Nonstop3h 05m
Allegiant Air
Deal found 6/11$139
This Cheapflightsfares deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:11 am
DEN
-
TYS
Nonstop2h 50m
Allegiant Air
Sun 8/97:00 am
TYS
-
DEN
Nonstop3h 21m
Allegiant Air
Deal found 6/13$144
This Cheapflightsfares deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:55 am
DEN
-
TYS
Nonstop2h 49m
Allegiant Air
Thu 9/177:00 am
TYS
-
DEN
Nonstop3h 05m
Allegiant Air
Deal found 6/13$148
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/309:01 am
DEN
-
TYS
Nonstop2h 50m
Allegiant Air
Sun 8/27:00 am
TYS
-
DEN
Nonstop3h 11m
Allegiant Air
Deal found 6/12$156
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/113:51 pm
COS
-
TYS
1 stop5h 27m
American Airlines
Wed 8/196:03 am
TYS
-
COS
1 stop5h 15m
American Airlines
Deal found 6/11$201
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:15 am
COS
-
TYS
1 stop6h 05m
Southwest
Wed 8/197:00 am
TYS
-
COS
2 stops7h 40m
Southwest
Deal found 6/11$241
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:20 am
COS
-
TYS
1 stop7h 10m
Southwest
Thu 8/202:05 pm
TYS
-
COS
1 stop7h 50m
Southwest
Deal found 6/10$260
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:27 am
COS
-
TYS
2 stops10h 25m
Delta
Wed 8/1911:38 am
TYS
-
COS
2 stops12h 00m
Delta
Deal found 6/11$267
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:49 am
COS
-
TYS
1 stop11h 42m
Allegiant Air
Sun 8/96:09 pm
TYS
-
COS
1 stop16h 50m
Allegiant Air
Deal found 6/9$293

Find flight deals from Colorado to Knoxville

Keep the following information in mind while searching for Colorado to Knoxville flight deals. Data was last updated June 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$123
(Cheapflightsfares)

One-way from

$61
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$290

Good round-trip deal

$160 or less

Good one-way deal

$98 or less
Provider with most accurate pricing for Denver Intl-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Knoxville McGhee Tyson flights.
Search Deals
From Colorado to Knoxville McGhee Tyson
Search Deals
One-way flight from Colorado to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($56 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals
Price to beat on a round-trip flight from Colorado to Knoxville McGhee Tyson.
Search Deals
Price to beat on a one-way flight from Colorado to Knoxville McGhee Tyson.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Colorado to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 13, 2026.
Use the filters below to find and compare flights from Colorado to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Tue 8/11

11:27 am-11:52 pm

2 stops10h 25m

Knoxville McGhee Tyson

Wed 8/19

6:12 pm-9:38 pm

1 stop5h 26m

$306

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 9/4

4:33 pm-11:52 pm

1 stop5h 19m

Knoxville McGhee Tyson

Tue 9/8

5:30 am-8:41 am

1 stop5h 11m

$313

MontroseKnoxville

MTJ - TYS

MTJTYS

Montrose County

Wed 8/26

3:24 pm-10:29 pm

1 stop5h 05m

Knoxville McGhee Tyson

Sat 8/29

9:00 am-2:27 pm

1 stop7h 27m

$319

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Sat 8/29

6:00 am-3:46 pm

1 stop7h 46m

Knoxville McGhee Tyson

Wed 9/2

7:00 am-10:33 am

1 stop5h 33m

$329

Grand JunctionKnoxville

GJT - TYS

GJTTYS

Grand Junction Regnl

Wed 8/12

5:30 am-4:58 pm

2 stops9h 28m

Knoxville McGhee Tyson

Tue 8/18

4:50 pm-8:35 pm

1 stop5h 45m

$334

Grand JunctionKnoxville

GJT - TYS

GJTTYS

Grand Junction Regnl

Fri 8/28

1:40 pm-11:59 pm

2 stops8h 19m

Knoxville McGhee Tyson

Sat 9/5

4:50 pm-9:59 pm

1 stop7h 09m

$334

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Mon 8/10

6:00 am-1:34 pm

1 stop5h 34m

Knoxville McGhee Tyson

Thu 8/13

4:38 pm-9:38 pm

1 stop7h 00m

$353

Grand JunctionKnoxville

GJT - TYS

GJTTYS

Grand Junction Regnl

Fri 9/11

7:00 am-4:42 pm

1 stop7h 42m

Knoxville McGhee Tyson

Tue 9/15

5:35 pm-9:57 pm

1 stop6h 22m

$360

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Thu 8/6

6:00 am-1:25 pm

1 stop5h 25m

Knoxville McGhee Tyson

Sun 8/9

8:30 am-4:00 pm

2 stops9h 30m

$406

Grand JunctionKnoxville

GJT - TYS

GJTTYS

Grand Junction Regnl

Sat 10/24

1:34 pm-10:14 pm

1 stop6h 40m

Knoxville McGhee Tyson

Wed 10/28

4:25 pm-10:10 pm

1 stop7h 45m

$419

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Showing 1-10 of 40 resultsSorted by cheapest first
1
2
3
4

Best time to book a flight from Colorado to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Knoxville

What is the cheapest month to book a flight from Colorado to Knoxville?

Currently, October is the cheapest month in which you can book a flight from Colorado to Knoxville (average of $39). Flying from Colorado to Knoxville in April is currently the most expensive (average of $119). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to TYS?

Find hourly flight availability from Colorado to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 13, 2026.

When flying from Colorado to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Colorado to Knoxville

Explore weekly flight availability from Colorado to Knoxville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 13, 2026.

The most flights from USCO to TYS are scheduled on a Monday (5 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (2 on average).

How much does it cost to fly round-trip from Colorado to Knoxville?

How far ahead should I book a flight from Colorado to Knoxville?

To ensure you get the cheapest price possible for a flight from Colorado to Knoxville, you should look to book at least 82 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

Related info for your journey

Find useful and relevant information for your journey from Colorado to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Colorado?

    For a flight from Colorado to Knoxville, you will be flying into McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • How popular is this Colorado to Knoxville flight route?

    The Colorado to Knoxville McGhee Tyson flight path was viewed by 19 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Colorado to Knoxville?

    There are many flights that can get you from Colorado to Knoxville in 5h 05m. Fly via Delta, United Airlines, or American Airlines to get the fastest option. The distance from Colorado to Knoxville is about 1325 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Colorado to Knoxville one-way?

    One-way options have recently been found by users for as low as $58 on Frontier. Other airlines that offer cheap prices include Allegiant Air from $58 and Delta from $124 one-way.

  • What are the most popular routes from Colorado to Knoxville?

    Most travelers choose Denver Intl - Knoxville McGhee Tyson, Colorado Springs - Knoxville McGhee Tyson or Grand Junction Regnl - Knoxville McGhee Tyson when deciding on the best route from Colorado to Knoxville.

  • What are the most reliable airlines from Colorado to Knoxville?

    Before booking your flight to Knoxville from Colorado, check out the most reliable airlines to get you to your destination on time: Frontier (82%), Volaris (82%), SkyWest Airlines( 82%).

  • What are the cheapest flights from Colorado to Knoxville?

    Looking for the cheapest flight from Colorado to Knoxville? While on average our users pay $231, our data indicates the cheapest price to be $67. The most popular route (Denver Intl - Knoxville McGhee Tyson), is priced around $105.

  • Can I find deals for flights from Colorado to Knoxville that include hotel bookings?

    Yes. In addition to deals on Colorado to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Knoxville.

  • Can I find deals for business class flights from Colorado to Knoxville?

    Yes. Cheapflights offers flight deals from Colorado to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to Knoxville?

    Currently, October is the cheapest month in which you can book a flight from Colorado to Knoxville (average of $39). Flying from Colorado to Knoxville in April is currently the most expensive (average of $119). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Colorado to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Newark to Nashville flights
John F Kennedy Intl to Nashville flights
Los Angeles to Nashville flights
LaGuardia to Nashville flights
Boston to Nashville flights
Philadelphia to Nashville flights
Reagan-National to Nashville flights
Seattle to Nashville flights
Dallas/Fort Worth to Nashville flights
O'Hare Intl to Nashville flights
Hobby to Nashville flights
Baltimore to Nashville flights
Dulles Intl to Nashville flights
Denver to Nashville flights
George Bush Intcntl to Nashville flights
Raleigh to Nashville flights
San Francisco to Nashville flights
Sky Harbor Intl to Nashville flights
Ontario to Nashville flights
Cleveland to Nashville flights
Minneapolis to Nashville flights
LaGuardia to Knoxville flights
Orlando to Nashville flights
Detroit to Nashville flights
San Diego to Nashville flights
Dallas/Fort Worth to Knoxville flights
Austin to Nashville flights
Miami to Nashville flights
Newark to Memphis flights
LaGuardia to Memphis flights
Tampa to Nashville flights
George Bush Intcntl to Knoxville flights
Burbank to Nashville flights
John F Kennedy Intl to Knoxville flights
O'Hare Intl to Knoxville flights
Salt Lake City to Nashville flights
Sacramento to Nashville flights
Portland to Nashville flights
Hobby to Knoxville flights
Dulles Intl to Knoxville flights
Love Field to Nashville flights
Hartford to Nashville flights
Charlotte to Nashville flights
Las Vegas to Nashville flights
Providence to Nashville flights
Baltimore to Knoxville flights
John F Kennedy Intl to Memphis flights
Fort Lauderdale to Nashville flights
Reagan-National to Memphis flights
San Antonio to Nashville flights

Top 6 airlines flying from Colorado to Knoxville

Discover the top 6 airlines that operate flights from Colorado to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$59Average$141FlexibilityNo cancel feeOn-time88%
FrontierCheapest$84Average$215FlexibilityNo cancel feeOn-time62%
DeltaCheapest$124Average$267FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$204Average$375FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$228Average$392FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$248Average$393FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.