HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$44+ Cheap flights from Colorado to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/24. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — TYS
May 30 — Jun 61
Sat 5/30
Sat 6/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Colorado to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Colorado to Knoxville

Cheapest flights from Colorado to Knoxville
Explore the most affordable flight options available from Colorado to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.

This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/102:46 pm
DEN
-
TYS
Nonstop2h 51m
Frontier
Mon 6/158:32 pm
TYS
-
DEN
Nonstop3h 40m
Frontier
Deal found 4/29$173
This Frontier deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/202:46 pm
DEN
-
TYS
Nonstop2h 50m
Frontier
Fri 7/248:32 pm
TYS
-
DEN
Nonstop3h 23m
Frontier
Deal found 4/28$175
This Super.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:37 pm
DEN
-
TYS
Nonstop2h 47m
Frontier
Fri 6/58:32 pm
TYS
-
DEN
Nonstop3h 30m
Frontier
Deal found 4/29$176
This Cheapflightsfares deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/49:05 am
DEN
-
TYS
Nonstop2h 47m
Allegiant Air
Sun 6/77:00 am
TYS
-
DEN
Nonstop3h 15m
Allegiant Air
Deal found 4/29$177
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:46 pm
DEN
-
TYS
Nonstop2h 47m
Frontier
Fri 6/58:32 pm
TYS
-
DEN
Nonstop3h 30m
Frontier
Deal found 4/29$178
This deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/262:46 pm
DEN
-
TYS
Nonstop2h 51m
Frontier
Wed 7/18:32 pm
TYS
-
DEN
Nonstop3h 40m
Frontier
Deal found 4/29$181
This Frontier deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/72:46 pm
DEN
-
TYS
Nonstop2h 50m
Frontier
Fri 8/148:32 pm
TYS
-
DEN
Nonstop3h 23m
Frontier
Deal found 4/28$184
This Mytrip deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/49:05 am
DEN
-
TYS
Nonstop2h 47m
Multiple Airlines
Mon 6/88:32 pm
TYS
-
DEN
Nonstop3h 30m
Multiple Airlines
Deal found 4/26$185
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/262:46 pm
DEN
-
TYS
Nonstop2h 51m
Multiple Airlines
Thu 7/27:00 am
TYS
-
DEN
Nonstop3h 11m
Multiple Airlines
Deal found 4/27$189
This Frontier deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/82:46 pm
DEN
-
TYS
Nonstop2h 47m
Frontier
Fri 6/128:32 pm
TYS
-
DEN
Nonstop3h 40m
Frontier
Deal found 4/28$190
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:49 am
COS
-
TYS
1 stop11h 42m
Allegiant Air
Sun 8/98:15 am
TYS
-
COS
1 stop26h 44m
Allegiant Air
Deal found 4/25$291
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am
COS
-
TYS
1 stop7h 07m
Delta
Sat 9/194:00 pm
TYS
-
COS
1 stop7h 15m
Delta
Deal found 4/28$306

Find flight deals from Colorado to Knoxville

Keep the following information in mind while searching for Colorado to Knoxville flight deals. Data was last updated April 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$173
(CheapOair)

One-way from

$44
(Frontier)

Popular in

March

Cheapest in

August

Average price

$319

Good round-trip deal

$279 or less

Good one-way deal

$106 or less
Provider with most accurate pricing for Denver Intl-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Knoxville McGhee Tyson flights.
Search Deals
From Colorado to Knoxville McGhee Tyson
Search Deals
One-way flight from Colorado to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($65 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals
Price to beat on a round-trip flight from Colorado to Knoxville McGhee Tyson.
Search Deals
Price to beat on a one-way flight from Colorado to Knoxville McGhee Tyson.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Colorado to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Colorado to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Wed 9/16

6:00 am-3:07 pm

1 stop7h 07m

Knoxville McGhee Tyson

Sat 9/19

4:00 pm-9:15 pm

1 stop7h 15m

$306

MontroseKnoxville

MTJ - TYS

MTJTYS

Montrose County

Fri 5/22

1:40 pm-10:19 pm

1 stop6h 39m

Knoxville McGhee Tyson

Mon 5/25

6:30 am-11:43 am

1 stop7h 13m

$335

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Thu 8/27

10:57 am-9:46 pm

2 stops8h 49m

Knoxville McGhee Tyson

Sun 8/30

4:00 pm-9:15 pm

1 stop7h 15m

$339

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Mon 6/1

6:05 am-2:20 pm

1 stop6h 15m

Knoxville McGhee Tyson

Fri 6/5

1:59 pm-5:57 pm

1 stop5h 58m

$355

Grand JunctionKnoxville

GJT - TYS

GJTTYS

Grand Junction Regnl

Wed 8/19

1:30 pm-10:38 pm

1 stop7h 08m

Knoxville McGhee Tyson

Sun 8/23

4:56 pm-8:36 pm

1 stop5h 40m

$362
Quickest round-trip

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 7/3

5:25 pm-10:19 pm

Nonstop2h 54m

Knoxville McGhee Tyson

Mon 7/6

7:19 pm-12:30 am

1 stop7h 11m

$377

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Fri 5/29

6:00 am-2:33 pm

1 stop6h 33m

Knoxville McGhee Tyson

Wed 6/3

5:59 pm-9:27 pm

1 stop5h 28m

$381

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Mon 7/20

5:45 am-2:48 pm

1 stop7h 03m

Knoxville McGhee Tyson

Fri 7/24

3:59 pm-10:44 pm

1 stop8h 45m

$387

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Wed 6/3

5:25 pm-10:19 pm

Nonstop2h 54m

Knoxville McGhee Tyson

Sat 6/6

7:19 pm-12:30 am

1 stop7h 11m

$393

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Tue 5/12

1:25 pm-11:44 pm

2 stops8h 19m

Knoxville McGhee Tyson

Sat 5/16

7:00 am-10:47 am

1 stop5h 47m

$396

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 52 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Colorado to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Knoxville

How far ahead should I book a flight from Colorado to Knoxville?

To ensure you get the cheapest price possible for a flight from Colorado to Knoxville, you should look to book at least 44 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Colorado to Knoxville?

Currently, October is the cheapest month in which you can book a flight from Colorado to Knoxville (average of $39). Flying from Colorado to Knoxville in March is currently the most expensive (average of $98). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to TYS?

Find hourly flight availability from Colorado to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2026.

When flying from Colorado to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Colorado to Knoxville

Explore weekly flight availability from Colorado to Knoxville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 30, 2026.

The most flights from USCO to TYS are scheduled on a Thursday (4 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

How much does it cost to fly round-trip from Colorado to Knoxville?

Related info for your journey

Find useful and relevant information for your journey from Colorado to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Colorado?

    For a flight from Colorado to Knoxville, you will be flying into McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • How popular is this Colorado to Knoxville flight route?

    The Colorado to Knoxville McGhee Tyson flight path was viewed by 19 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Colorado to Knoxville?

    There are many flights that can get you from Colorado to Knoxville in 7h 07m. Fly via Delta, United Airlines, or American Airlines to get the fastest option. The distance from Colorado to Knoxville is about 1153 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Colorado to Knoxville one-way?

    One-way options have recently been found by users for as low as $58 on Frontier. Other airlines that offer cheap prices include Allegiant Air from $58 and Delta from $124 one-way.

  • What are the most popular routes from Colorado to Knoxville?

    Most travelers choose Denver Intl - Knoxville McGhee Tyson, Colorado Springs - Knoxville McGhee Tyson or Durango La Plata County - Knoxville McGhee Tyson when deciding on the best route from Colorado to Knoxville.

  • What are the most reliable airlines from Colorado to Knoxville?

    Before booking your flight to Knoxville from Colorado, check out the most reliable airlines to get you to your destination on time: United Airlines (83%), SkyWest Airlines (82%), Frontier( 77%).

  • What are the cheapest flights from Colorado to Knoxville?

    Looking for the cheapest flight from Colorado to Knoxville? While on average our users pay $598, our data indicates the cheapest price to be $64. The most popular route (Denver Intl - Knoxville McGhee Tyson), is priced around $144.

  • Can I find deals for flights from Colorado to Knoxville that include hotel bookings?

    Yes. In addition to deals on Colorado to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Knoxville.

  • Can I find deals for business class flights from Colorado to Knoxville?

    Yes. Cheapflights offers flight deals from Colorado to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to Knoxville?

    Currently, October is the cheapest month in which you can book a flight from Colorado to Knoxville (average of $39). Flying from Colorado to Knoxville in March is currently the most expensive (average of $98). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Colorado to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Newark to Nashville flights
LaGuardia to Nashville flights
John F Kennedy Intl to Nashville flights
Los Angeles to Nashville flights
Seattle to Nashville flights
Boston to Nashville flights
O'Hare Intl to Nashville flights
Reagan-National to Nashville flights
Philadelphia to Nashville flights
Dallas/Fort Worth to Nashville flights
Dulles Intl to Nashville flights
Denver to Nashville flights
Baltimore to Nashville flights
Minneapolis to Nashville flights
San Francisco to Nashville flights
Hobby to Nashville flights
Detroit to Nashville flights
Austin to Nashville flights
Raleigh to Nashville flights
Tampa to Nashville flights
Ontario to Nashville flights
George Bush Intcntl to Nashville flights
LaGuardia to Knoxville flights
Sky Harbor Intl to Nashville flights
Fort Lauderdale to Nashville flights
O'Hare Intl to Knoxville flights
Dallas/Fort Worth to Knoxville flights
San Diego to Nashville flights
George Bush Intcntl to Knoxville flights
Orlando to Nashville flights
Newark to Memphis flights
Providence to Nashville flights
Charlotte to Nashville flights
Hobby to Knoxville flights
John F Kennedy Intl to Knoxville flights
Portland to Nashville flights
Miami to Nashville flights
Milwaukee to Nashville flights
Hartford to Nashville flights
Dallas/Fort Worth to Memphis flights
Sacramento to Nashville flights
Hobby to Memphis flights
Cleveland to Nashville flights
Baltimore to Memphis flights
Salt Lake City to Nashville flights
Los Angeles to Memphis flights
Denver to Knoxville flights
San Jose to Nashville flights
West Palm Beach to Nashville flights
Santa Ana to Nashville flights

Top 6 airlines flying from Colorado to Knoxville

Discover the top 6 airlines that operate flights from Colorado to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$61Average$140FlexibilityNo cancel feeOn-time88%
FrontierCheapest$81Average$198FlexibilityNo cancel feeOn-time62%
DeltaCheapest$124Average$274FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$204Average$423FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$228Average$392FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$248Average$347FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.