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Knoxville

$67+ Cheap flights from Colorado to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/26. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — TYS
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheap flight deals from Colorado to Knoxville

Keep the following information in mind while searching for Colorado to Knoxville flight deals. Data was last updated April 30, 2025.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$121
(Mytrip)

One-way from

$67
(Booking.com)

Popular in

March

Cheapest in

August

Average price

$248

Good round-trip deal

$117 or less

Good one-way deal

$87 or less
Provider with most accurate pricing for Denver Intl-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Denver Intl-Knoxville McGhee Tyson flights.
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From Colorado to Knoxville McGhee Tyson
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One-way flight from Colorado to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 10% potential increase in price ($29 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Colorado to Knoxville McGhee Tyson.
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Price to beat on a one-way flight from Colorado to Knoxville McGhee Tyson.
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Find flight deals from Colorado to Knoxville

Cheapest flights from Colorado to Knoxville
Explore the most affordable flight options available from Colorado to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/118:21 amDEN - TYS
Nonstop2h 44mAllegiant Air
Thu 5/156:30 amTYS - DEN
Nonstop3h 08mAllegiant Air
Deal found 4/29$121
This FlightHub deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/188:28 amDEN - TYS
Nonstop2h 45mMultiple Airlines
Sun 5/255:30 pmTYS - DEN
Nonstop3h 31mMultiple Airlines
Deal found 4/28$150
This Cheapflightsfares deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/311:41 amDEN - TYS
Nonstop2h 48mFrontier
Thu 7/175:25 pmTYS - DEN
Nonstop3h 15mFrontier
Deal found 4/28$174
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/284:43 pmCOS - TYS
1 stop5h 15mAmerican Airlines
Wed 6/256:25 pmTYS - COS
1 stop5h 57mAmerican Airlines
Deal found 4/28$224
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/35:26 pmDEN - TYS
Nonstop3h 02mUnited Airlines
Tue 6/107:00 amTYS - DEN
1 stop5h 35mUnited Airlines
Deal found 4/28$239
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/66:35 amDEN - TYS
1 stop7h 57mDelta
Sat 8/95:35 pmTYS - DEN
1 stop6h 54mDelta
Deal found 4/28$249
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/187:00 amDEN - TYS
1 stop5h 34mAmerican Airlines
Sat 5/246:28 pmTYS - DEN
1 stop7h 31mAmerican Airlines
Deal found 4/29$264
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/143:30 pmMTJ - TYS
1 stop4h 52mUnited Airlines
Mon 8/184:35 pmTYS - MTJ
1 stop6h 16mUnited Airlines
Deal found 4/28$309
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/154:38 pmDRO - TYS
1 stop5h 15mAmerican Airlines
Sun 8/176:00 amTYS - DRO
1 stop5h 44mAmerican Airlines
Deal found 4/28$318
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/151:30 pmDRO - TYS
2 stops7h 57mUnited Airlines
Mon 8/187:00 amTYS - DRO
2 stops7h 27mUnited Airlines
Deal found 4/28$353
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/48:15 amCOS - TYS
2 stops13h 29mDelta
Wed 7/910:45 amTYS - COS
2 stops12h 18mDelta
Deal found 4/28$368
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/216:00 amCOS - TYS
2 stops8h 54mUnited Airlines
Sun 5/257:00 amTYS - COS
1 stop6h 08mUnited Airlines
Deal found 4/29$374

Cheapflights Fare Finder

Customize your flight search to find flights from Colorado to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from Colorado to Knoxville that are best for you.

Fly from

Colorado

Fly to

Knoxville

Route

Depart

Return

Price

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sun 5/11

8:21 am-1:05 pm

Nonstop2h 44m

Knoxville McGhee Tyson

Thu 5/15

6:30 am-7:38 am

Nonstop3h 08m

$121

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sun 5/18

8:28 am-1:13 pm

Nonstop2h 45m

Knoxville McGhee Tyson

Sun 5/25

5:30 pm-7:01 pm

Nonstop3h 31m

$150

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 7/3

11:41 am-4:29 pm

Nonstop2h 48m

Knoxville McGhee Tyson

Thu 7/17

5:25 pm-6:40 pm

Nonstop3h 15m

$174

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Wed 5/28

4:43 pm-11:58 pm

1 stop5h 15m

Knoxville McGhee Tyson

Wed 6/25

6:25 pm-10:22 pm

1 stop5h 57m

$224

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Wed 8/20

5:28 pm-10:30 pm

Nonstop3h 02m

Knoxville McGhee Tyson

Sun 8/24

4:40 pm-5:52 pm

Nonstop3h 12m

$229

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Wed 8/6

6:35 am-4:32 pm

1 stop7h 57m

Knoxville McGhee Tyson

Sat 8/9

5:35 pm-10:29 pm

1 stop6h 54m

$249

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sun 5/18

7:00 am-2:34 pm

1 stop5h 34m

Knoxville McGhee Tyson

Sun 5/25

6:28 pm-11:59 pm

1 stop7h 31m

$264

MontroseKnoxville

MTJ - TYS

MTJTYS

Montrose County

Thu 8/14

3:30 pm-10:22 pm

1 stop4h 52m

Knoxville McGhee Tyson

Mon 8/18

4:35 pm-8:51 pm

1 stop6h 16m

$309

DurangoKnoxville

DRO - TYS

DROTYS

Durango La Plata County

Fri 8/15

4:38 pm-11:53 pm

1 stop5h 15m

Knoxville McGhee Tyson

Sun 8/17

6:00 am-9:44 am

1 stop5h 44m

$318

DurangoKnoxville

DRO - TYS

DROTYS

Durango La Plata County

Fri 8/15

1:30 pm-11:27 pm

2 stops7h 57m

Knoxville McGhee Tyson

Mon 8/18

7:00 am-12:27 pm

2 stops7h 27m

$353

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 25 results
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Best time to book a flight from Colorado to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Knoxville

What is the cheapest month to book a flight from Colorado to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Colorado to Knoxville (average of $296). Flying from Colorado to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to TYS?

Find hourly flight availability from Colorado to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

When flying from Colorado to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 30, 2025.
Get a feel of what it's like to fly with Delta, United Airlines and Allegiant Air from Colorado to Knoxville by reading reviews from past customers. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,929 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,929 reviews
Delta
8.0
Very good
7,929 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,929 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,929 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,929 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
6.0
Okay
3,284 reviews
Delta
8.0
Very good
7,929 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Colorado to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Colorado?

    For a flight from Colorado to Knoxville, you will be flying into McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • How popular is this Colorado to Knoxville flight route?

    The Colorado to Knoxville McGhee Tyson flight path was viewed by 6 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Colorado to Knoxville one-way?

    One-way options have recently been found by users for as low as $67 on Allegiant Air. Other airlines that offer cheap prices include Frontier from $70 and American Airlines from $227 one-way.

  • What are the most popular routes from Colorado to Knoxville?

    Most travelers choose Denver Intl - Knoxville McGhee Tyson, Colorado Springs - Knoxville McGhee Tyson or Montrose County - Knoxville McGhee Tyson when deciding on the best route from Colorado to Knoxville.

  • What are the most reliable airlines from Colorado to Knoxville?

    Before booking your flight to Knoxville from Colorado, check out the most reliable airlines to get you to your destination on time: Frontier (100%), Allegiant Air (93%), SkyWest Airlines( 90%).

  • What are the cheapest flights from Colorado to Knoxville?

    Looking for the cheapest flight from Colorado to Knoxville? While on average our users pay $174, our data indicates the cheapest price to be $60. The most popular route (Denver Intl - Knoxville McGhee Tyson), is priced around $124.

  • Can I find deals for flights from Colorado to Knoxville that include hotel bookings?

    Yes. In addition to deals on Colorado to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Knoxville.

  • Can I find deals for business class flights from Colorado to Knoxville?

    Yes. Cheapflights offers flight deals from Colorado to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Colorado to Knoxville (average of $296). Flying from Colorado to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Colorado?

Book flights to Colorado if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Alternative routes for Colorado to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Colorado to Knoxville

Discover the top 5 airlines that operate flights from Colorado to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$61Average$145FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$67Average$130FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$148Average$382FlexibilityNo cancel feeOn-time71%
DeltaCheapest$215Average$334FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$225Average$493FlexibilityNo cancel feeOn-time69%

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