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$243+ Cheap flights from Charleston, WV to Knoxville (CRW - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/29. Fares are subject to change and may not be available on all flights or dates of travel.
CRW — TYS
Oct 19 — Oct 261
Sun 10/19
Sun 10/26
1 adult, Economy
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Cheap flight deals from Charleston to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CRW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 19, 2025.

Round-trip from

$316
(American Airlines)

One-way from

$243
(American Airlines)
From Charleston Yeager to Knoxville McGhee Tyson
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One-way flight from Charleston Yeager to Knoxville McGhee Tyson
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Find flight deals from Charleston to Knoxville

Cheapest flights from Charleston to Knoxville
Explore the most affordable flight options available from Charleston to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2025.

This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/157:11 pmCRW - TYS
1 stop3h 56mAmerican Airlines
Wed 10/225:00 amTYS - CRW
1 stop5h 50mAmerican Airlines
Deal found 9/17$316
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/63:49 pmCRW - TYS
1 stop3h 10mDelta
Tue 12/95:25 amTYS - CRW
1 stop5h 11mDelta
Deal found 9/16$326
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/611:17 amCRW - TYS
1 stop6h 41mAmerican Airlines
Tue 12/912:46 pmTYS - CRW
2 stops9h 07mAmerican Airlines
Deal found 9/16$372
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/37:00 amCRW - TYS
1 stop15h 50mUnited Airlines
Tue 10/710:51 amTYS - CRW
1 stop10h 35mUnited Airlines
Deal found 9/17$497

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 19, 2025.
Use the filters below to find and compare flights from Charleston to Knoxville that are best for you.

Fly from

Charleston

Fly to

Knoxville

Route

Depart

Return

Price

CharlestonKnoxville

CRW - TYS

CRWTYS

Charleston Yeager

Wed 10/15

7:11 pm-11:07 pm

1 stop3h 56m

Knoxville McGhee Tyson

Wed 10/22

5:00 am-10:50 am

1 stop5h 50m

$316

CharlestonKnoxville

CRW - TYS

CRWTYS

Charleston Yeager

Sat 12/6

3:49 pm-6:59 pm

1 stop3h 10m

Knoxville McGhee Tyson

Tue 12/9

5:25 am-10:36 am

1 stop5h 11m

$326

CharlestonKnoxville

CRW - TYS

CRWTYS

Charleston Yeager

Sat 12/6

11:17 am-5:58 pm

1 stop6h 41m

Knoxville McGhee Tyson

Tue 12/9

12:46 pm-9:53 pm

2 stops9h 07m

$372

CharlestonKnoxville

CRW - TYS

CRWTYS

Charleston Yeager

Fri 10/3

7:00 am-10:50 pm

1 stop15h 50m

Knoxville McGhee Tyson

Tue 10/7

10:51 am-9:26 pm

1 stop10h 35m

$497

CharlestonKnoxville

CRW - TYS

CRWTYS

Charleston Yeager

Mon 12/29

1:26 pm-7:41 pm

1 stop6h 15m

$243

CharlestonKnoxville

CRW - TYS

CRWTYS

Charleston Yeager

Mon 12/29

7:36 pm-10:18 am

2 stops38h 42m

$430

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Best time to book a flight from Charleston to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston, West Virginia to Knoxville?

    There are many flights that can get you from Charleston, West Virginia to Knoxville in 3h 10m. Fly via American Airlines or Delta to get the fastest option. There are 221 mi between Charleston, West Virginia and Knoxville. This flight may include one or multiple stops.

  • Can I find deals for flights from Charleston to Knoxville that include hotel bookings?

    Yes. In addition to deals on Charleston to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Knoxville.

  • Can I find deals for business class flights from Charleston to Knoxville?

    Yes. Cheapflights offers flight deals from Charleston to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston, West Virginia to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Charleston, West Virginia to Knoxville (average of $295). Flying from Charleston, West Virginia to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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