What are the cheapest airlines to fly from Syracuse to Key Largo one-way?

$57 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on JetBlue and Delta, with prices starting from $104 and $109, respectively.

In terms of precipitation, rainfall in Key Largo ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Key Largo when rainfall is around 1.6 in.

If weather is an important factor for your trip to Key Largo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

What are the cheapest flights from Syracuse to Key Largo?

On average you can expect to pay $549 for a flight from Syracuse to Key Largo. The cheapest flight overall is $163 while the most popular route, (Syracuse Hancock Intl - Miami) is currently priced at $219.

What are the most popular airlines that fly from Syracuse to Key Largo?

American Airlines, Delta and JetBlue are the most popular airlines when flying from Syracuse to Key Largo.

What airport do you fly from for flights from Syracuse to Key Largo?

If you book a flight to Key Largo from Syracuse, you will be flying from Hancock Intl, which is the city’s only airport. Syracuse Hancock Intl (SYR) is located 4.8 mi from the center of Syracuse. There are 0 flights from Hancock Intl to Key Largo per day from 5 different airlines.

Can I find deals for flights from Syracuse to Key Largo that include hotel bookings?

Yes. In addition to deals on Syracuse to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Syracuse to Key Largo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Key Largo.

Can I find deals for business class flights from Syracuse to Key Largo?

Yes. Cheapflights offers flight deals from Syracuse to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Find Cheap Flights from Syracuse to Key Largo

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Find flight deals from Syracuse to Key Largo

Most accurate provider	FlightHub 3 stars
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Popular in	March
Cheapest in	July
Average price	$398

Provider with most accurate pricing for Syracuse Hancock Intl-Miami flight deals.

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Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Miami flights.

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Highest demand for flights based on searches. 13% potential increase in price ($67 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).

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Average for round-trip flights in October 2026

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Everything you need to know about your flight from Syracuse to Key Largo

What is the cheapest time of day to fly from SYR to KE9?

It’s optimal to fly from Syracuse to Key Largo in the evening. By choosing this option you can save up to 56% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Key Largo

Peruse reviews from past customers who have flown with Delta,United Airlines, andAllegiant Air from Syracuse to Key Largo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.8

Good

8,653 reviews

Reviews

1 / 20

4.0

Okay

Joel,May 2026

ATL - JAX

The flight was delivered 50 minutes and taxing took what felt like 20 minutes to takeoff.

Delta

7.8

Good

8,653 reviews

Delta

7.8

Good

8,653 reviews

Reviews

1 / 20

4.0

Okay

Joel,May 2026

ATL - JAX

The flight was delivered 50 minutes and taxing took what felt like 20 minutes to takeoff.

United Airlines

7.4

Good

10,339 reviews

Delta

7.8

Good

8,653 reviews

Reviews

1 / 20

4.0

Okay

Joel,May 2026

ATL - JAX

The flight was delivered 50 minutes and taxing took what felt like 20 minutes to takeoff.

Allegiant Air

7.3

Good

679 reviews

Delta

7.8

Good

8,653 reviews

Reviews

1 / 20

4.0

Okay

Joel,May 2026

ATL - JAX

The flight was delivered 50 minutes and taxing took what felt like 20 minutes to takeoff.

JetBlue

7.1

Good

3,045 reviews

Delta

7.8

Good

8,653 reviews

Reviews

1 / 20

4.0

Okay

Joel,May 2026

ATL - JAX

The flight was delivered 50 minutes and taxing took what felt like 20 minutes to takeoff.

American Airlines

7.0

Good

12,142 reviews

Delta

7.8

Good

8,653 reviews

Reviews

1 / 20

4.0

Okay

Joel,May 2026

ATL - JAX

The flight was delivered 50 minutes and taxing took what felt like 20 minutes to takeoff.

Related info for your journey

What airport do you fly from for flights from Syracuse to Key Largo?
If you book a flight to Key Largo from Syracuse, you will be flying from Hancock Intl, which is the city’s only airport. Syracuse Hancock Intl (SYR) is located 4.8 mi from the center of Syracuse. There are 0 flights from Hancock Intl to Key Largo per day from 5 different airlines.
What are the cheapest airlines to fly from Syracuse to Key Largo one-way?
$57 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on JetBlue and Delta, with prices starting from $104 and $109, respectively.
What are the cheapest flights from Syracuse to Key Largo?
On average you can expect to pay $549 for a flight from Syracuse to Key Largo. The cheapest flight overall is $163 while the most popular route, (Syracuse Hancock Intl - Miami) is currently priced at $219.
Can I find deals for flights from Syracuse to Key Largo that include hotel bookings?
Yes. In addition to deals on Syracuse to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Syracuse to Key Largo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Key Largo.
Can I find deals for business class flights from Syracuse to Key Largo?
Yes. Cheapflights offers flight deals from Syracuse to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Top 5 airlines flying from Syracuse to Key Largo

Airline	Cheapest	Average	Flexibility	On-time
Allegiant Air	Cheapest$85	Average$235	FlexibilityNo cancel fee	On-time88%
JetBlue	Cheapest$107	Average$250	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$108	Average$399	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$168	Average$450	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$216	Average$434	FlexibilityNo cancel fee	On-time69%

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Cheap flights from Syracuse (SYR) to Key Largo, FL

Find cheap flights from Syracuse to Key Largo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Syracuse to Key Largo

Most accurate provider

Most trusted provider

Popular in

Cheapest in

Average price

Cheapflights Insights

What is the cheapest time of day to fly from SYR to KE9?

It’s optimal to fly from Syracuse to Key Largo in the evening. By choosing this option you can save up to 56% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Key Largo

Peruse reviews from past customers who have flown with Delta,United Airlines, andAllegiant Air from Syracuse to Key Largo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

What airport do you fly from for flights from Syracuse to Key Largo?

What are the cheapest airlines to fly from Syracuse to Key Largo one-way?

What are the cheapest flights from Syracuse to Key Largo?

Can I find deals for flights from Syracuse to Key Largo that include hotel bookings?

How can I find direct flights from Syracuse to Key Largo?

Can I find deals for business class flights from Syracuse to Key Largo?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Syracuse to Key Largo

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Key Largo by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Syracuse to Key Largo by cabin class

Find flights from Syracuse to Key Largo, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Syracuse and Key Largo flights

Browse other Syracuse and Key Largo flight options. Last updated on October 11, 2026.

Other flights from Syracuse

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