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Key Largo

$72+ Cheap flights from Syracuse (SYR) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/24. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — MIA
Dec 4 — Dec 111
Thu 12/4
Thu 12/11
1 adult, Economy
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Cheapflights Tip: The best prices from Syracuse Hancock Intl to Key Largo are usually found in September or August, booked 78 days in advance, depart on a Sunday or Wednesday and return on a Tuesday

Cheap flight deals from Syracuse to Key Largo

Keep the following information in mind while searching for Syracuse to Key Largo flight deals. Data was last updated November 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$238
(Kiwi.com)

One-way from

$72
(Frontier)

Popular in

March

Cheapest in

September

Average price

$398
Provider with most accurate pricing for Syracuse Hancock Intl-Miami flight deals.
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Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Miami flights.
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From Syracuse Hancock Intl to Key Largo
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One-way flight from Syracuse Hancock Intl to Key Largo
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Highest demand for flights based on searches. 15% potential increase in price ($68 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Syracuse to Key Largo

Cheapest flights from Syracuse to Key Largo
Explore the most affordable flight options available from Syracuse to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/110:24 amSYR - MIA
1 stop13h 16mFrontier
Sun 12/75:30 amMIA - SYR
2 stops36h 20mFrontier
Deal found 11/3$239
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:19 pmSYR - MIA
1 stop6h 31mDelta
Sat 12/68:10 amMIA - SYR
1 stop7h 50mDelta
Deal found 11/4$251
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:15 amSYR - MIA
1 stop8h 55mUnited Airlines
Wed 12/1012:50 pmMIA - SYR
2 stops10h 29mUnited Airlines
Deal found 11/3$256
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/219:58 amSYR - MIA
2 stops13h 10mMultiple Airlines
Sun 11/2312:28 pmMIA - SYR
1 stop21h 11mMultiple Airlines
Deal found 11/4$261
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/110:24 amSYR - MIA
1 stop13h 16mMultiple Airlines
Mon 12/85:30 amMIA - SYR
2 stops30h 35mMultiple Airlines
Deal found 11/3$268
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/611:29 amSYR - MIA
1 stop7h 41mDelta
Thu 12/1110:32 amMIA - SYR
1 stop7h 24mDelta
Deal found 11/3$270
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:40 pmSYR - MIA
1 stop5h 12mAmerican Airlines
Sat 12/67:45 pmMIA - SYR
Nonstop3h 25mAmerican Airlines
Deal found 11/4$279
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1911:50 amSYR - MIA
2 stops26h 35mMultiple Airlines
Sun 11/2312:28 pmMIA - SYR
1 stop21h 11mMultiple Airlines
Deal found 11/4$287
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/63:24 pmSYR - MIA
1 stop6h 11mAmerican Airlines
Sun 12/146:40 amMIA - SYR
1 stop4h 56mAmerican Airlines
Deal found 11/4$289
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/611:29 amSYR - MIA
1 stop7h 41mDelta
Sun 12/76:00 amMIA - SYR
1 stop5h 13mDelta
Deal found 11/3$295

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Syracuse to Key Largo that are best for you.

Fly from

Syracuse

Fly to

Key Largo

Route

Depart

Return

Price

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Tue 12/2

6:00 am-11:21 am

1 stop5h 21m

Miami

Tue 12/9

3:39 pm-12:05 am

1 stop8h 26m

$251

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Sat 12/6

11:29 am-7:10 pm

1 stop7h 41m

Miami

Thu 12/11

5:20 pm-12:05 am

1 stop6h 45m

$270

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Sat 3/14

6:50 pm-12:57 am

1 stop6h 07m

Miami

Wed 3/18

8:45 am-4:21 pm

1 stop7h 36m

$289

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Wed 11/19

6:00 am-11:21 am

1 stop5h 21m

Miami

Mon 11/24

3:42 pm-11:58 pm

1 stop8h 16m

$318

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Thu 11/20

6:00 am-11:21 am

1 stop5h 21m

Miami

Mon 11/24

3:42 pm-11:58 pm

1 stop8h 16m

$318

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Tue 1/6

5:48 am-11:16 am

1 stop5h 28m

Miami

Thu 1/8

7:15 am-1:10 pm

1 stop5h 55m

$344

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Tue 12/16

3:57 pm-11:52 pm

1 stop7h 55m

Miami

Sat 12/20

8:35 pm-11:59 pm

Nonstop3h 24m

$349

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Wed 1/21

8:00 am-9:54 pm

2 stops13h 54m

Miami

Fri 1/23

7:15 am-1:10 pm

1 stop5h 55m

$349

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Tue 2/24

6:00 am-5:29 pm

2 stops11h 29m

Miami

Thu 2/26

6:00 am-12:20 pm

1 stop6h 20m

$349

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Fri 12/5

8:20 pm-2:49 pm

2 stops42h 29m

$100

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Showing 1-10 of 18 results
1
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Best time to book a flight from Syracuse to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Key Largo

How far ahead should I book a flight from Syracuse to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Syracuse to Key Largo. Price data was last updated on October 31, 2025.

The best time to book flights from Syracuse to Key Largo is 78 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Syracuse to Key Largo?

Currently, January is the cheapest month in which you can book a flight from Syracuse to Key Largo (average of $71). Flying from Syracuse to Key Largo in December is currently the most expensive (average of $121). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SYR to KE9?

Find hourly flight availability from Syracuse to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 4, 2025.

It’s optimal to fly from Syracuse to Key Largo in the evening. By choosing this option you can save up to 48% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Syracuse to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Syracuse to Key Largo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Syracuse to Key Largo flight should consider departing on Monday evenings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated November 4, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Syracuse to Key Largo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,002 reviews

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,002 reviews
Delta
7.9
Good
8,002 reviews

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,998 reviews
Delta
7.9
Good
8,002 reviews

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
11,038 reviews
Delta
7.9
Good
8,002 reviews

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
JetBlue
7.2
Good
2,907 reviews
Delta
7.9
Good
8,002 reviews

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Frontier
5.8
Fair
3,116 reviews
Delta
7.9
Good
8,002 reviews

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Syracuse to Key Largo?

    If you book a flight to Key Largo from Syracuse, you will be flying from Hancock Intl, which is the city’s only airport. Syracuse Hancock Intl (SYR) is located 4.8 mi from the center of Syracuse. There are 0 flights from Hancock Intl to Key Largo per day from 6 different airlines.

  • How long is the flight from Syracuse to Key Largo?

    Airlines like Delta fly from Syracuse to Key Largo in about 5h 21m. The time it takes to get you to your destination can typically vary by up to . The distance between Syracuse and Key Largo is about 1219 mi.

  • What are the cheapest flights from Syracuse to Key Largo?

    On average you can expect to pay $1,008 for a flight from Syracuse to Key Largo. The cheapest flight overall is $654 while the most popular route, (Syracuse Hancock Intl - Miami) is currently priced at $234.

  • Can I find deals for flights from Syracuse to Key Largo that include hotel bookings?

    Yes. In addition to deals on Syracuse to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Key Largo.

  • Can I find deals for business class flights from Syracuse to Key Largo?

    Yes. Cheapflights offers flight deals from Syracuse to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Key Largo?

    Currently, January is the cheapest month in which you can book a flight from Syracuse to Key Largo (average of $71). Flying from Syracuse to Key Largo in December is currently the most expensive (average of $121). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 6 airlines flying from Syracuse to Key Largo

Discover the top 6 airlines that operate flights from Syracuse to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$72Average$222FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$94Average$263FlexibilityNo cancel feeOn-time88%
DeltaCheapest$147Average$335FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$177Average$348FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$192Average$411FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$212Average$457FlexibilityNo cancel feeOn-time69%

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