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Key Largo

$100+ Cheap flights from Syracuse (SYR) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — MIA
Nov 21 — Nov 281
Fri 11/21
Fri 11/28
1 adult, Economy
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Cheapflights Tip: The best prices from Syracuse Hancock Intl to Key Largo are usually found in September or August, booked 78 days in advance, depart on a Monday or Thursday and return on a Tuesday

Cheap flight deals from Syracuse to Key Largo

Keep the following information in mind while searching for Syracuse to Key Largo flight deals. Data was last updated October 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$232
(Kiwi.com)

One-way from

$100
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$328
Provider with most accurate pricing for Syracuse Hancock Intl-Miami flight deals.
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Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Miami flights.
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From Syracuse Hancock Intl to Key Largo
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One-way flight from Syracuse Hancock Intl to Key Largo
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Highest demand for flights based on searches. 15% potential increase in price ($70 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Syracuse to Key Largo

Cheapest flights from Syracuse to Key Largo
Explore the most affordable flight options available from Syracuse to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/167:40 pmSYR - MIA
2 stops37h 32mFrontier
Sun 11/235:30 amMIA - SYR
1 stop28h 09mFrontier
Deal found 10/19$236
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/19:00 pmSYR - MIA
2 stops22h 47mMultiple Airlines
Thu 12/1112:10 pmMIA - SYR
1 stop26h 12mMultiple Airlines
Deal found 10/21$246
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/27:01 pmSYR - MIA
1 stop5h 45mDelta
Wed 12/106:30 pmMIA - SYR
1 stop5h 03mDelta
Deal found 10/20$251
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/64:04 pmSYR - MIA
1 stop7h 19mDelta
Sun 12/147:59 pmMIA - SYR
1 stop14h 50mDelta
Deal found 10/20$252
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:30 amSYR - MIA
1 stop10h 45mDelta
Sun 12/147:59 pmMIA - SYR
1 stop14h 50mDelta
Deal found 10/20$253
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/152:56 pmSYR - MIA
1 stop8h 08mUnited Airlines
Tue 11/1812:51 pmMIA - SYR
2 stops10h 22mUnited Airlines
Deal found 10/20$256
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:00 amSYR - MIA
1 stop9h 29mAmerican Airlines
Sat 12/139:53 pmMIA - SYR
1 stop13h 40mAmerican Airlines
Deal found 10/21$259
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/97:50 pmSYR - MIA
2 stops15h 32mMultiple Airlines
Thu 11/137:07 pmMIA - SYR
1 stop16h 01mMultiple Airlines
Deal found 10/19$264
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1412:03 pmSYR - MIA
1 stop12h 31mFrontier
Sun 11/165:01 amMIA - SYR
2 stops13h 44mFrontier
Deal found 10/19$267
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/75:30 amSYR - MIA
1 stop10h 45mDelta
Mon 12/157:59 pmMIA - SYR
1 stop14h 50mDelta
Deal found 10/20$268

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 22, 2025.
Use the filters below to find and compare flights from Syracuse to Key Largo that are best for you.

Fly from

Syracuse

Fly to

Key Largo

Route

Depart

Return

Price

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Wed 2/11

6:50 pm-12:25 am

1 stop5h 35m

Miami

Wed 2/25

8:45 am-4:21 pm

1 stop7h 36m

$251

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Wed 1/7

6:18 am-2:48 pm

1 stop8h 30m

Miami

Wed 1/14

3:35 pm-11:51 pm

1 stop8h 16m

$251

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Wed 1/7

2:42 pm-11:59 pm

2 stops9h 17m

Miami

Wed 1/14

9:00 am-4:15 pm

1 stop7h 15m

$256

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Tue 11/18

11:25 am-6:51 pm

1 stop7h 26m

Miami

Tue 11/25

3:42 pm-11:58 pm

1 stop8h 16m

$270

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Thu 2/5

12:15 pm-8:50 pm

1 stop8h 35m

Miami

Thu 2/12

5:59 pm-11:51 pm

1 stop5h 52m

$289

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Wed 3/25

6:00 am-2:39 pm

1 stop8h 39m

Miami

Tue 3/31

8:45 am-4:21 pm

1 stop7h 36m

$289

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Sat 3/14

6:50 pm-12:57 am

1 stop6h 07m

Miami

Wed 3/18

8:45 am-4:21 pm

1 stop7h 36m

$289

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Thu 1/29

12:15 pm-8:50 pm

1 stop8h 35m

Miami

Thu 2/5

3:35 pm-11:51 pm

1 stop8h 16m

$289

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Tue 12/16

6:12 am-2:25 pm

1 stop8h 13m

Miami

Sat 12/20

5:19 pm-11:16 pm

1 stop5h 57m

$315

SyracuseMiami

SYR - MIA

SYRMIA

Syracuse Hancock Intl

Tue 2/24

6:18 am-2:48 pm

1 stop8h 30m

Miami

Thu 2/26

5:59 pm-10:15 am

1 stop16h 16m

$317

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/20

Showing 1-10 of 20 results
1
2

Best time to book a flight from Syracuse to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Key Largo

How far ahead should I book a flight from Syracuse to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Syracuse to Key Largo. Price data was last updated on October 17, 2025.

The best time to book flights from Syracuse to Key Largo is 78 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Syracuse to Key Largo?

Currently, January is the cheapest month in which you can book a flight from Syracuse to Key Largo (average of $71). Flying from Syracuse to Key Largo in December is currently the most expensive (average of $128). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SYR to KE9?

Find hourly flight availability from Syracuse to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 22, 2025.

It’s optimal to fly from Syracuse to Key Largo in the evening. By choosing this option you can save up to 47% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Syracuse to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Syracuse to Key Largo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Syracuse to Key Largo flight should consider departing on Monday evenings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated October 22, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Syracuse to Key Largo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,979 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
7,979 reviews
Delta
7.9
Good
7,979 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,988 reviews
Delta
7.9
Good
7,979 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
11,028 reviews
Delta
7.9
Good
7,979 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
JetBlue
7.2
Good
2,908 reviews
Delta
7.9
Good
7,979 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Allegiant Air
7.2
Good
694 reviews
Delta
7.9
Good
7,979 reviews

Boarding

8.2

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Syracuse to Key Largo?

    If you book a flight to Key Largo from Syracuse, you will be flying from Hancock Intl, which is the city’s only airport. Syracuse Hancock Intl (SYR) is located 4.8 mi from the center of Syracuse. There are 0 flights from Hancock Intl to Key Largo per day from 6 different airlines.

  • How long is the flight from Syracuse to Key Largo?

    Airlines like Delta and United Airlines fly from Syracuse to Key Largo in about 5h 35m. The time it takes to get you to your destination can typically vary by up to 3h 42m. The distance between Syracuse and Key Largo is about 1219 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest flights from Syracuse to Key Largo?

    On average you can expect to pay $1,023 for a flight from Syracuse to Key Largo. The cheapest flight overall is $418 while the most popular route, (Syracuse Hancock Intl - Miami) is currently priced at $246.

  • Can I find deals for flights from Syracuse to Key Largo that include hotel bookings?

    Yes. In addition to deals on Syracuse to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Key Largo.

  • Can I find deals for business class flights from Syracuse to Key Largo?

    Yes. Cheapflights offers flight deals from Syracuse to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Key Largo?

    Currently, January is the cheapest month in which you can book a flight from Syracuse to Key Largo (average of $71). Flying from Syracuse to Key Largo in December is currently the most expensive (average of $128). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Syracuse to Key Largo

Discover the top 6 airlines that operate flights from Syracuse to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$72Average$232FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$94Average$277FlexibilityNo cancel feeOn-time88%
JetBlueCheapest$127Average$357FlexibilityNo cancel feeOn-time62%
DeltaCheapest$143Average$335FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$192Average$410FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$216Average$457FlexibilityNo cancel feeOn-time69%

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