$268+ Cheap flights from Charleston, WV (CRW) to Key Largo, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
CRW — MIA
Sep 22 — Sep 291
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
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One-way
Cheapest flights from Charleston to Key LargoExplore the most affordable flight options available from Charleston to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 23, 2026.
Explore the most affordable flight options available from Charleston to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 23, 2026.
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:45 pm -
1 stop5h 07m
Sat 9/126:00 am -
1 stop4h 21m
Deal found 8/21![Delta logo]()
$290
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:50 pm -
1 stop8h 41m
Sun 11/227:00 am -
1 stop6h 15m
Deal found 8/18![United Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:03 am -
1 stop7h 51m
Tue 9/83:57 pm -
1 stop8h 02m
Deal found 8/22![United Airlines logo]()
$314
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:24 pm -
1 stop4h 15m
Sat 9/126:12 am -
1 stop5h 53m
Deal found 8/18![American Airlines logo]()
$340
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:50 pm -
1 stop8h 41m
Mon 11/237:00 am -
1 stop6h 15m
Deal found 8/21![United Airlines logo]()
$343
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:54 pm -
1 stop6h 01m
Sat 10/36:00 am -
1 stop4h 27m
Deal found 8/18![Delta logo]()
$352
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:30 pm -
1 stop4h 43m
Tue 9/811:10 am -
2 stops7h 15m
Deal found 8/22![American Airlines logo]()
$378
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:02 am -
1 stop7h 52m
Mon 8/313:57 pm -
1 stop8h 02m
Deal found 8/20![United Airlines logo]()
$394
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:14 pm -
1 stop6h 22m
Tue 9/299:59 am -
1 stop5h 55m
Deal found 8/20![American Airlines logo]()
$406
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:35 pm -
1 stop6h 24m
Mon 12/146:34 pm -
1 stop4h 59m
Deal found 8/19![Delta logo]()
$414
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/278:17 pm -
1 stop4h 39m
Sat 10/38:15 am -
2 stops8h 05m
Deal found 8/18![American Airlines logo]()
$440
Best flights from Charleston to Key LargoDiscover carefully curated flight deals from Charleston to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 23, 2026.
Discover carefully curated flight deals from Charleston to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 23, 2026.
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:03 am -
1 stop7h 51m
Tue 9/83:57 pm -
1 stop8h 02m
Deal found 8/22![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/314:48 pm -
1 stop4h 42m
Sun 9/66:00 am -
1 stop4h 27m
Deal found 8/19![Delta logo]()
$522
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:50 pm -
1 stop8h 41m
Mon 11/237:00 am -
1 stop6h 15m
Deal found 8/21![United Airlines logo]()
$343
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:00 am -
1 stop7h 59m
Tue 10/64:01 pm -
1 stop7h 58m
Deal found 8/21![United Airlines logo]()
$510
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:02 am -
2 stops15h 57m
Sun 11/87:00 am -
1 stop6h 15m
Deal found 8/21![United Airlines logo]()
$574
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:50 pm -
1 stop8h 41m
Sun 11/157:00 am -
1 stop6h 15m
Deal found 8/22![United Airlines logo]()
$581
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
1 stop15h 26m
Fri 10/308:45 am -
2 stops28h 28m
Deal found 8/22![United Airlines logo]()
$584
Last-minute flights from Charleston to Key LargoDiscover last-minute flight deals from Charleston to Key Largo. Data last updated August 23, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Key Largo. Data last updated August 23, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:14 pm -
1 stop6h 22m
Tue 9/299:59 am -
1 stop5h 55m
Deal found 8/20![American Airlines logo]()
$406
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:14 pm -
1 stop6h 22m
Wed 8/2610:10 am -
1 stop6h 34m
Deal found 8/18![American Airlines logo]()
$456
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:02 am -
1 stop7h 52m
Mon 8/313:57 pm -
1 stop8h 02m
Deal found 8/20![United Airlines logo]()
$394
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:03 am -
1 stop7h 51m
Tue 9/83:57 pm -
1 stop8h 02m
Deal found 8/22![United Airlines logo]()
$314
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:30 pm -
1 stop4h 43m
Tue 9/811:10 am -
2 stops7h 15m
Deal found 8/22![American Airlines logo]()
$378
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:45 pm -
1 stop5h 07m
Sat 9/126:00 am -
1 stop4h 21m
Deal found 8/21![Delta logo]()
$290
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:24 pm -
1 stop4h 15m
Sat 9/126:12 am -
1 stop5h 53m
Deal found 8/18![American Airlines logo]()
$340
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/184:24 pm -
1 stop4h 15m
Sun 9/208:52 am -
1 stop6h 04m
Deal found 8/18![American Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:54 pm -
1 stop6h 01m
Sat 10/36:00 am -
1 stop4h 27m
Deal found 8/18![Delta logo]()
$352
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/278:17 pm -
1 stop4h 39m
Sat 10/38:15 am -
2 stops8h 05m
Deal found 8/18![American Airlines logo]()
$440
One-way flights from Charleston to Key LargoSearch for one-way flight options from Charleston to Key Largo. Find affordable one-way fares based on user searches. Data last updated August 23, 2026.
Search for one-way flight options from Charleston to Key Largo. Find affordable one-way fares based on user searches. Data last updated August 23, 2026.
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:00 am -
1 stop7h 51m
Deal found 8/18![United Airlines logo]()
$268
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:00 am -
1 stop7h 51m
Deal found 8/19![United Airlines logo]()
$308
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:33 pm -
1 stop4h 32m
Deal found 8/18![Delta logo]()
$327
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:00 am -
1 stop7h 51m
Deal found 8/19![United Airlines logo]()
$484
Find flight deals from Charleston to Key Largo
Keep the following information in mind while searching for Charleston to Key Largo flight deals. Data was last updated August 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $290 (Delta) |
One-way from | $268 (United Airlines) |
Popular in | July |
Cheapest in | December |
Average price | $404 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 23, 2026.
Use the filters below to find and compare flights from Charleston to Key Largo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonMiami
CRW Charleston Yeager - MIA Miami
CRWMIA
Charleston Yeager
Sat 9/5
7:03 am-2:54 pm
1 stop7h 51m
Miami
Tue 9/8
3:57 pm-11:59 pm
1 stop8h 02m
$314
CharlestonMiami
CRW Charleston Yeager - MIA Miami
CRWMIA
Charleston Yeager
Wed 11/18
1:50 pm-10:31 pm
1 stop8h 41m
Miami
Mon 11/23
7:00 am-1:15 pm
1 stop6h 15m
$343
CharlestonMiami
CRW Charleston Yeager - MIA Miami
CRWMIA
Charleston Yeager
Sat 10/3
7:00 am-2:59 pm
1 stop7h 59m
Miami
Tue 10/6
4:01 pm-11:59 pm
1 stop7h 58m
$510
Quickest round-trip
CharlestonMiami
CRW Charleston Yeager - MIA Miami
CRWMIA
Charleston Yeager
Mon 8/31
4:48 pm-9:30 pm
1 stop4h 42m
Miami
Sun 9/6
6:00 am-10:27 am
1 stop4h 27m
$522
CharlestonMiami
CRW Charleston Yeager - MIA Miami
CRWMIA
Charleston Yeager
Thu 11/5
6:02 am-9:59 pm
2 stops15h 57m
Miami
Sun 11/8
7:00 am-1:15 pm
1 stop6h 15m
$574
CharlestonMiami
CRW Charleston Yeager - MIA Miami
CRWMIA
Charleston Yeager
Fri 11/6
1:50 pm-10:31 pm
1 stop8h 41m
Miami
Sun 11/15
7:00 am-1:15 pm
1 stop6h 15m
$581
CharlestonMiami
CRW Charleston Yeager - MIA Miami
CRWMIA
Charleston Yeager
Sat 10/24
7:00 am-10:26 pm
1 stop15h 26m
Miami
Fri 10/30
8:45 am-1:13 pm
2 stops28h 28m
$584
Cheapest one-way
CharlestonMiami
CRW Charleston Yeager - MIA Miami
CRWMIA
Charleston Yeager
Tue 9/22
7:00 am-2:51 pm
1 stop7h 51m
$268
Quickest one-way
CharlestonMiami
CRW Charleston Yeager - MIA Miami
CRWMIA
Charleston Yeager
Wed 9/23
2:33 pm-7:05 pm
1 stop4h 32m
$327
CharlestonMiami
CRW Charleston Yeager - MIA Miami
CRWMIA
Charleston Yeager
Wed 9/23
7:00 am-4:31 pm
2 stops9h 31m
$525
Showing 1-10 of 12 resultsSorted by cheapest first
Best time to book a flight from Charleston to Key Largo
Have a flexible travel schedule? Discover the best time to fly to Key Largo from Charleston with our price prediction graph.
CRW-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to Key Largo
CRW-KE9
CRW-MIA
How much does it cost to fly round-trip from Charleston, West Virginia to Key Largo?
Airfare is below average for this route at the moment.
Charleston, West Virginia to Key Largo flights typically cost between $347 and $417 in September.The cheapest round-trip price found within the last 5 days was $290 on Delta (Sep 9-Sep 12).
Reviews of airlines servicing Key Largo
Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated August 23, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Charleston to Key Largo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Overall
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Entertainment
7.8
Overall
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Entertainment
7.8
Overall
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Charleston to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Key Largo by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Charleston to Key Largo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charleston and Key Largo flights
Browse other Charleston and Key Largo flight options. Last updated on August 23, 2026.
Other flights from Charleston
Browse through other flights departing from Charleston. Flights are based on user searches made on Cheapflights and were last updated on August 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Charleston to Key Largo flights
Consider these flights traveling from Charleston to Key Largo.
Top 2 airlines flying from Charleston to Key Largo
Discover the top 2 airlines that operate flights from Charleston to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$238 | Average$452 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$238 | Average$389 | FlexibilityNo cancel fee | On-timeN/A |