$124+ Cheap flights from Charleston (CHS) to Key Largo, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/21. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MIA
Jul 24 — Jul 311
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to Key Largo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Charleston to Key Largo are usually found in September or August, booked 76 days in advance, depart on a Friday or Thursday and return on a Tuesday
Cheap flight deals from Charleston to Key Largo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Charleston to Key LargoExplore the most affordable flight options available from Charleston to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 24, 2026.
Explore the most affordable flight options available from Charleston to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 24, 2026.
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1711:04 am
CHS
- MIA
Nonstop1h 44m
American Airlines
Fri 7/2410:16 pm
MIA
- CHS
Nonstop1h 43m
American Airlines
Deal found 6/19![American Airlines logo]()
$246
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2411:04 am
CHS
- MIA
Nonstop1h 44m
American Airlines
Mon 7/278:30 am
MIA
- CHS
Nonstop1h 52m
American Airlines
Deal found 6/24![American Airlines logo]()
$247
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:13 pm
CHS
- MIA
Nonstop1h 45m
American Airlines
Sat 7/188:30 am
MIA
- CHS
Nonstop1h 52m
American Airlines
Deal found 6/22![American Airlines logo]()
$252
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1610:27 am
CHS
- MIA
1 stop5h 07m
American Airlines
Mon 9/213:44 pm
MIA
- CHS
Nonstop1h 46m
American Airlines
Deal found 6/24![American Airlines logo]()
$257
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:11 am
CHS
- MIA
1 stop6h 09m
Delta
Mon 9/217:37 pm
MIA
- CHS
1 stop4h 20m
Delta
Deal found 6/24![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/222:10 pm
CHS
- MIA
2 stops8h 05m
Southwest
Wed 7/2911:25 am
MIA
- CHS
1 stop4h 45m
Southwest
Deal found 6/22![Southwest logo]()
$272
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:15 am
CHS
- MIA
1 stop6h 56m
American Airlines
Fri 9/410:15 pm
MIA
- CHS
Nonstop1h 44m
American Airlines
Deal found 6/23![American Airlines logo]()
$277
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/213:00 pm
CHS
- MIA
1 stop6h 25m
Southwest
Tue 7/286:00 am
MIA
- CHS
2 stops7h 30m
Southwest
Deal found 6/23![Southwest logo]()
$282
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:10 pm
CHS
- MIA
2 stops8h 05m
Southwest
Wed 7/226:35 am
MIA
- CHS
2 stops9h 35m
Southwest
Deal found 6/19![Southwest logo]()
$283
Best flights from Charleston to Key LargoDiscover carefully curated flight deals from Charleston to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 24, 2026.
Discover carefully curated flight deals from Charleston to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 24, 2026.
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/178:20 am
CHS
- MIA
1 stop4h 42m
Delta
Mon 7/206:00 pm
MIA
- CHS
1 stop5h 19m
Delta
Deal found 6/23![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:40 am
CHS
- MIA
1 stop7h 45m
Southwest
Mon 8/317:00 am
MIA
- CHS
2 stops9h 40m
Southwest
Deal found 6/23![Southwest logo]()
$322
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:00 am
CHS
- MIA
1 stop8h 57m
United Airlines
Tue 7/2112:30 pm
MIA
- CHS
1 stop9h 18m
United Airlines
Deal found 6/19![United Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:10 am
CHS
- MIA
2 stops8h 15m
Southwest
Sun 8/25:35 am
MIA
- CHS
2 stops6h 55m
Southwest
Deal found 6/23![Southwest logo]()
$347
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:15 pm
CHS
- MIA
2 stops8h 50m
Southwest
Mon 9/2112:25 pm
MIA
- CHS
1 stop6h 10m
Southwest
Deal found 6/23![Southwest logo]()
$352
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/304:10 pm
CHS
- MIA
1 stop7h 10m
Southwest
Sun 8/23:15 pm
MIA
- CHS
1 stop7h 40m
Southwest
Deal found 6/24![Southwest logo]()
$372
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/198:05 am
CHS
- MIA
2 stops11h 10m
Southwest
Sun 10/45:55 am
MIA
- CHS
2 stops7h 35m
Southwest
Deal found 6/19![Southwest logo]()
$373
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:50 am
CHS
- MIA
2 stops11h 30m
Southwest
Tue 7/76:00 am
MIA
- CHS
2 stops7h 30m
Southwest
Deal found 6/22![Southwest logo]()
$378
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:40 am
CHS
- MIA
2 stops12h 40m
Southwest
Sat 9/127:45 am
MIA
- CHS
2 stops11h 35m
Southwest
Deal found 6/21![Southwest logo]()
$403
Last-minute flights from Charleston to Key LargoDiscover last-minute flight deals from Charleston to Key Largo. Data last updated June 24, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Key Largo. Data last updated June 24, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:09 pm
CHS
- MIA
Nonstop1h 46m
American Airlines
Wed 7/85:00 pm
MIA
- CHS
Nonstop1h 51m
American Airlines
Deal found 6/24![American Airlines logo]()
$322
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:10 pm
CHS
- MIA
1 stop7h 40m
Southwest
Sat 7/46:50 am
MIA
- CHS
1 stop11h 30m
Southwest
Deal found 6/20![Southwest logo]()
$332
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/38:13 pm
CHS
- MIA
Nonstop1h 45m
American Airlines
Sat 7/45:42 pm
MIA
- CHS
Nonstop1h 51m
American Airlines
Deal found 6/22![American Airlines logo]()
$307
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/31:00 pm
CHS
- MIA
1 stop7h 21m
American Airlines
Fri 7/310:16 pm
MIA
- CHS
Nonstop1h 43m
American Airlines
Deal found 6/22![American Airlines logo]()
$311
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:10 pm
CHS
- MIA
1 stop7h 05m
Southwest
Sat 7/47:05 am
MIA
- CHS
2 stops11h 15m
Southwest
Deal found 6/22![Southwest logo]()
$338
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:13 pm
CHS
- MIA
Nonstop1h 45m
American Airlines
Mon 7/1310:16 pm
MIA
- CHS
Nonstop1h 43m
American Airlines
Deal found 6/22![American Airlines logo]()
$277
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:00 am
CHS
- MIA
Nonstop1h 43m
American Airlines
Mon 7/68:30 am
MIA
- CHS
Nonstop1h 52m
American Airlines
Deal found 6/19![American Airlines logo]()
$292
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/41:10 pm
CHS
- MIA
1 stop4h 59m
Delta
Mon 7/136:00 am
MIA
- CHS
1 stop4h 13m
Delta
Deal found 6/22![Delta logo]()
$297
One-way flights from Charleston to Key LargoSearch for one-way flight options from Charleston to Key Largo. Find affordable one-way fares based on user searches. Data last updated June 24, 2026.
Search for one-way flight options from Charleston to Key Largo. Find affordable one-way fares based on user searches. Data last updated June 24, 2026.
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:00 am
CHS
- MIA
Nonstop1h 43m
American Airlines
Deal found 6/24![American Airlines logo]()
$124
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/188:13 pm
CHS
- MIA
Nonstop1h 45m
American Airlines
Deal found 6/22![American Airlines logo]()
$125
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:34 pm
CHS
- MIA
Nonstop1h 45m
American Airlines
Deal found 6/22![American Airlines logo]()
$127
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:04 am
CHS
- MIA
Nonstop1h 44m
American Airlines
Deal found 6/23![American Airlines logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:45 am
CHS
- MIA
2 stops14h 08m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:18 am
CHS
- MIA
2 stops11h 46m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$132
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:10 am
CHS
- MIA
1 stop6h 44m
Delta
Deal found 6/24![Delta logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:56 pm
CHS
- MIA
2 stops19h 25m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/164:02 pm
CHS
- MIA
2 stops31h 03m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:44 pm
CHS
- MIA
2 stops22h 45m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$138
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:10 am
CHS
- MIA
1 stop5h 47m
Delta
Deal found 6/22![Delta logo]()
$139
Find flight deals from Charleston to Key Largo
Keep the following information in mind while searching for Charleston to Key Largo flight deals. Data was last updated June 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $247 (American Airlines) |
One-way from | $124 (American Airlines) |
Popular in | April |
Cheapest in | September |
Average price | $371 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 24, 2026.
Use the filters below to find and compare flights from Charleston to Key Largo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
CharlestonMiami
CHS - MIA
CHSMIA
Charleston
Fri 7/17
8:20 am-1:02 pm
1 stop4h 42m
Miami
Mon 7/20
6:00 pm-11:19 pm
1 stop5h 19m
$267
CharlestonMiami
CHS - MIA
CHSMIA
Charleston
Thu 8/27
8:40 am-4:25 pm
1 stop7h 45m
Miami
Mon 8/31
7:00 am-4:40 pm
2 stops9h 40m
$322
CharlestonMiami
CHS - MIA
CHSMIA
Charleston
Fri 7/17
6:00 am-2:57 pm
1 stop8h 57m
Miami
Tue 7/21
12:30 pm-9:48 pm
1 stop9h 18m
$337
CharlestonMiami
CHS - MIA
CHSMIA
Charleston
Tue 7/28
6:10 am-2:25 pm
2 stops8h 15m
Miami
Sun 8/2
5:35 am-12:30 pm
2 stops6h 55m
$347
CharlestonMiami
CHS - MIA
CHSMIA
Charleston
Thu 9/17
1:15 pm-10:05 pm
2 stops8h 50m
Miami
Mon 9/21
12:25 pm-6:35 pm
1 stop6h 10m
$352
CharlestonMiami
CHS - MIA
CHSMIA
Charleston
Thu 7/30
4:10 pm-11:20 pm
1 stop7h 10m
Miami
Sun 8/2
3:15 pm-10:55 pm
1 stop7h 40m
$372
CharlestonMiami
CHS - MIA
CHSMIA
Charleston
Sat 9/19
8:05 am-7:15 pm
2 stops11h 10m
Miami
Sun 10/4
5:55 am-1:30 pm
2 stops7h 35m
$373
CharlestonMiami
CHS - MIA
CHSMIA
Charleston
Sat 7/4
7:50 am-7:20 pm
2 stops11h 30m
Miami
Tue 7/7
6:00 am-1:30 pm
2 stops7h 30m
$378
CharlestonMiami
CHS - MIA
CHSMIA
Charleston
Sun 9/6
8:40 am-9:20 pm
2 stops12h 40m
Miami
Sat 9/12
7:45 am-7:20 pm
2 stops11h 35m
$403
Cheapest one-way
CharlestonMiami
CHS - MIA
CHSMIA
Charleston
Wed 8/19
11:25 am-4:57 pm
1 stop5h 32m
$134
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Charleston to Key Largo
Have a flexible travel schedule? Discover the best time to fly to Key Largo from Charleston with our price prediction graph.
CHS-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to Key Largo
CHS-KE9
CHS-MIA
What is the cheapest time of day to fly from CHS to KE9?
Find hourly flight availability from Charleston to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 24, 2026.
A simple way to save on the total cost of your ticket is to fly from Charleston to Key Largo in the afternoon. If you’re flexible enough to do this you can expect to save up to 30% on your trip compared to booking a flight in the morning.
Weekly flight availability from Charleston to Key Largo
Explore weekly flight availability from Charleston to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 24, 2026.
The most flights from CHS to KE9 are scheduled on a Wednesday (5 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (2 on average).
How much does it cost to fly round-trip from Charleston to Key Largo?
Reviews of airlines servicing Key Largo
Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated June 24, 2026.
Read reviews from past customers who have flown Delta,American Airlines, andJetBlue from Charleston to Key Largo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Crew
8.5
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Crew
8.5
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Crew
8.5
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Charleston to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip to Key Largo by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Charleston to Key Largo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charleston and Key Largo flights
Browse other Charleston and Key Largo flight options. Last updated on June 24, 2026.
Other flights from Charleston
Browse through other flights departing from Charleston. Flights are based on user searches made on Cheapflights and were last updated on June 24, 2026.
Popular flight searches
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Charleston to Key Largo flights
Consider these flights traveling from Charleston to Key Largo.
Top 4 airlines flying from Charleston to Key Largo
Discover the top 4 airlines that operate flights from Charleston to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$58 | Average$202 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$78 | Average$202 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$157 | Average$355 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$157 | Average$353 | FlexibilityNo cancel fee | On-time71% |