Key Largo

$61+ Cheap flights from Charleston (CHS) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/18. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MIA
Mar 6 — Mar 131
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Cheapflights Tip: The best prices from Charleston to Key Largo are usually found in August or September, booked 70 days in advance, depart on a Friday or Thursday and return on a Saturday

Cheap flight deals from Charleston to Key Largo

Cheapest flights from Charleston to Key Largo
Explore the most affordable flight options available from Charleston to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/75:00 pm
CHS
-
MIA
1 stop26h 13m
Spirit Airlines
Sat 3/1411:38 am
MIA
-
CHS
1 stop23h 31m
Spirit Airlines
Deal found 2/1$145
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:00 pm
CHS
-
MIA
2 stops19h 16m
Spirit Airlines
Tue 3/1012:52 pm
MIA
-
CHS
1 stop27h 13m
Spirit Airlines
Deal found 2/2$146
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:00 pm
CHS
-
MIA
2 stops19h 16m
Spirit Airlines
Tue 3/1711:38 am
MIA
-
CHS
1 stop23h 31m
Spirit Airlines
Deal found 2/2$159
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/156:15 am
CHS
-
MIA
2 stops8h 02m
Multiple Airlines
Fri 2/2712:52 pm
MIA
-
CHS
1 stop27h 13m
Multiple Airlines
Deal found 2/2$164
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/812:04 pm
CHS
-
MIA
1 stop7h 12m
Spirit Airlines
Tue 4/1411:38 am
MIA
-
CHS
1 stop21h 02m
Spirit Airlines
Deal found 2/3$165
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:00 pm
CHS
-
MIA
2 stops24h 53m
Multiple Airlines
Sat 3/1411:38 am
MIA
-
CHS
1 stop23h 31m
Multiple Airlines
Deal found 2/1$167
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1612:04 pm
CHS
-
MIA
1 stop7h 12m
Spirit Airlines
Tue 3/1711:38 am
MIA
-
CHS
1 stop23h 31m
Spirit Airlines
Deal found 2/2$172
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:35 pm
CHS
-
MIA
2 stops17h 41m
Multiple Airlines
Fri 2/2712:52 pm
MIA
-
CHS
1 stop27h 13m
Multiple Airlines
Deal found 2/2$173
This CheapOair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:04 pm
CHS
-
MIA
1 stop7h 12m
Spirit Airlines
Sat 4/187:35 am
MIA
-
CHS
2 stops15h 06m
Spirit Airlines
Deal found 2/3$175
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/205:00 pm
CHS
-
MIA
1 stop7h 14m
Spirit Airlines
Tue 2/249:53 pm
MIA
-
CHS
2 stops18h 12m
Spirit Airlines
Deal found 2/2$176

Find flight deals from Charleston to Key Largo

Keep the following information in mind while searching for Charleston to Key Largo flight deals. Data was last updated February 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$145
(Kiwi.com)

One-way from

$61
(Mytrip)

Popular in

March

Cheapest in

August

Average price

$309
Provider with most accurate pricing for Charleston-Miami flight deals.
Provider most trusted by Cheapflights users for Charleston-Miami flights.
From Charleston to Key Largo
One-way flight from Charleston to Key Largo
Highest demand for flights based on searches. 6% potential increase in price ($22 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Average for round-trip flights in February 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Charleston to Key Largo that are best for you.

Fly from

Charleston

Fly to

Key Largo

Route

Depart

Return

Price

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Fri 3/6

5:00 pm-5:53 pm

2 stops24h 53m

Miami

Sat 3/14

11:38 am-11:09 am

1 stop23h 31m

$167

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Fri 4/24

9:35 am-7:25 pm

1 stop9h 50m

Miami

Sat 5/2

7:35 am-10:41 pm

2 stops15h 06m

$218

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Tue 5/5

12:25 pm-6:35 pm

1 stop6h 10m

Miami

Thu 5/14

7:36 pm-12:09 am

1 stop4h 33m

$248

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Tue 5/5

5:20 am-12:11 pm

1 stop6h 51m

Miami

Fri 5/15

7:36 pm-12:09 am

1 stop4h 33m

$248

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Sat 3/7

5:00 pm-11:16 am

2 stops18h 16m

Miami

Sat 3/14

9:14 am-10:13 pm

3 stops12h 59m

$249

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Mon 4/20

9:35 am-5:18 pm

2 stops7h 43m

Miami

Fri 4/24

6:13 pm-10:41 pm

2 stops28h 28m

$254

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Tue 2/17

5:00 pm-12:16 pm

2 stops19h 16m

Miami

Fri 2/20

4:01 pm-5:40 pm

3 stops25h 39m

$257

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Tue 4/7

12:04 pm-7:16 pm

1 stop7h 12m

Miami

Sat 4/11

9:23 am-11:09 am

2 stops25h 46m

$266

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Fri 4/24

7:44 pm-12:54 am

1 stop5h 10m

Miami

Sat 5/2

7:04 am-11:20 am

1 stop4h 16m

$272

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Mon 4/27

5:20 am-10:46 am

1 stop5h 26m

Miami

Sat 5/2

6:00 am-11:20 am

1 stop5h 20m

$272

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/3

Showing 1-10 of 21 results
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Best time to book a flight from Charleston to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Key Largo

How far ahead should I book a flight from Charleston to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Charleston to Key Largo. Price data was last updated on January 30, 2026.

The best time to book flights from Charleston to Key Largo is 70 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Charleston to Key Largo?

Currently, March is the cheapest month in which you can book a flight from Charleston to Key Largo (average of $33). Flying from Charleston to Key Largo in June is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to KE9?

Find hourly flight availability from Charleston to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 4, 2026.

A simple way to save on the total cost of your ticket is to fly from Charleston to Key Largo in the afternoon. If you’re flexible enough to do this you can expect to save up to 31% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Charleston to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Charleston to Key Largo. Price data was last updated on January 31, 2026.

Travelers seeking maximum savings on their Charleston to Key Largo flight should consider departing on Tuesday at noon when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Charleston to Key Largo

Explore weekly flight availability from Charleston to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 4, 2026.

The most flights from CHS to KE9 are scheduled on a Monday (7 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated February 4, 2026.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Charleston to Key Largo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Charleston to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Charleston to Key Largo?

    Located just 10.2 mi from the city center, Charleston is the airport most travelers will use when flying to Key Largo from Charleston. Booking flights from Charleston (CHS) to Key Largo should be relatively easy as there are 6 daily outbound flights to Key Largo from 6 different airlines.

  • How popular is this Charleston to Key Largo flight route?

  • How long is the flight from Charleston to Key Largo?

    Airlines like Spirit Airlines and Delta fly from Charleston to Key Largo in about 6h 10m. The time it takes to get you to your destination can typically vary by up to 3h 40m. There are 490 mi between Charleston and Key Largo. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Charleston to Key Largo one-way?

    One-way options have recently been found by users for as low as $31 on Spirit Airlines. Other airlines that offer cheap prices include American Airlines from $78 and JetBlue from $78 one-way.

  • What are the most reliable airlines from Charleston to Key Largo?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Charleston to Key Largo on time: Envoy Air (100%), American Airlines (81%), Qatar Airways (81%).

  • What are the cheapest flights from Charleston to Key Largo?

    While on average a flight from Charleston to Key Largo is generally $690, our data shows the cheapest flight currently is $104. When looking at the most popular route, (Charleston - Miami), you can expect to pay $130 for that flight.

  • Can I find deals for flights from Charleston to Key Largo that include hotel bookings?

    Yes. In addition to deals on Charleston to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Key Largo.

  • Can I find deals for business class flights from Charleston to Key Largo?

    Yes. Cheapflights offers flight deals from Charleston to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Key Largo?

    Currently, March is the cheapest month in which you can book a flight from Charleston to Key Largo (average of $33). Flying from Charleston to Key Largo in June is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charleston to Key Largo

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Charleston to Key Largo

Discover the top 6 airlines that operate flights from Charleston to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$34Average$97FlexibilityNo cancel feeOn-time65%
JetBlueCheapest$78Average$192FlexibilityNo cancel feeOn-time62%
Breeze AirwaysCheapest$95Average$211FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$113Average$368FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$162Average$358FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$245Average$339FlexibilityNo cancel feeOn-time63%

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