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Key Largo

$51+ Cheap flights from Charleston (CHS) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MIA
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Charleston to Key Largo are usually found in September or August, booked 47 days in advance, depart on a Wednesday or Tuesday and return on a Saturday

Cheap flight deals from Charleston to Key Largo

Keep the following information in mind while searching for Charleston to Key Largo flight deals. Data was last updated septiembre 11, 2025.

Round-trip from

$127
(American Airlines)

One-way from

$51
(Southwest)

Popular in

December

Cheapest in

September

Average price

$192
From Charleston to Key Largo
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One-way flight from Charleston to Key Largo
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Highest demand for flights based on searches. 3% potential increase in price ($10 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Charleston to Key Largo

Cheapest flights from Charleston to Key Largo
Explore the most affordable flight options available from Charleston to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/277:08 amCHS - MIA
Nonstop1h 42mAmerican Airlines
lun. 10/610:15 pmMIA - CHS
Nonstop1h 44mAmerican Airlines
Deal found 9/10$127
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/27:08 amCHS - MIA
Nonstop1h 42mAmerican Airlines
lun. 10/610:15 pmMIA - CHS
Nonstop1h 44mAmerican Airlines
Deal found 9/9$128
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/46:00 amCHS - MIA
Nonstop1h 48mAmerican Airlines
vie. 12/127:05 amMIA - CHS
Nonstop1h 42mAmerican Airlines
Deal found 9/10$137
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/310:10 amCHS - MIA
Nonstop1h 38mAmerican Airlines
sáb. 10/49:46 pmMIA - CHS
Nonstop1h 51mAmerican Airlines
Deal found 9/10$142
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/31:00 pmCHS - MIA
1 stop7h 25mSouthwest
sáb. 12/66:05 amMIA - CHS
1 stop10h 45mSouthwest
Deal found 9/10$145
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/151:25 pmCHS - MIA
2 stops8h 15mSouthwest
mié. 11/191:30 pmMIA - CHS
1 stop6h 25mSouthwest
Deal found 9/10$146
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/89:27 amCHS - MIA
Nonstop1h 49mAmerican Airlines
vie. 12/1211:03 pmMIA - CHS
Nonstop1h 43mAmerican Airlines
Deal found 9/11$147
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/46:00 amCHS - MIA
1 stop6h 50mSouthwest
mar. 11/117:10 amMIA - CHS
1 stop9h 55mSouthwest
Deal found 9/10$151
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/89:22 amCHS - MIA
Nonstop1h 46mAmerican Airlines
sáb. 11/1510:15 pmMIA - CHS
Nonstop1h 44mAmerican Airlines
Deal found 9/10$153
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/86:55 pmCHS - MIA
1 stop5h 34mDelta
sáb. 11/157:00 amMIA - CHS
1 stop6h 05mDelta
Deal found 9/10$157
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/249:27 amCHS - MIA
Nonstop1h 46mAmerican Airlines
vie. 11/287:01 amMIA - CHS
Nonstop1h 42mAmerican Airlines
Deal found 9/10$159

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Charleston to Key Largo that are best for you.

Fly from

Charleston

Fly to

Key Largo

Route

Depart

Return

Price

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

vie. 10/3

10:10 am-11:48 am

Nonstop1h 38m

Miami

lun. 10/6

10:15 pm-11:59 pm

Nonstop1h 44m

$142

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

mar. 9/30

5:10 am-11:01 am

1 stop5h 51m

Miami

mié. 10/8

6:00 am-10:20 am

1 stop4h 20m

$157

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

sáb. 9/27

5:35 pm-12:23 am

1 stop6h 48m

Miami

lun. 10/6

6:15 pm-11:59 pm

1 stop5h 44m

$157

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

sáb. 10/11

10:22 am-11:58 am

Nonstop1h 36m

Miami

sáb. 10/18

8:08 am-9:52 am

Nonstop1h 44m

$157

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

sáb. 10/18

6:55 pm-12:29 am

1 stop5h 34m

Miami

mié. 10/22

6:00 am-10:20 am

1 stop4h 20m

$177

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

sáb. 10/18

6:55 pm-12:29 am

1 stop5h 34m

Miami

sáb. 10/25

6:00 am-11:49 am

1 stop5h 49m

$177

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

jue. 10/2

6:59 pm-12:23 am

1 stop5h 24m

Miami

lun. 10/6

7:39 pm-11:59 pm

1 stop4h 20m

$177

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

mar. 11/4

6:00 am-4:10 pm

2 stops10h 10m

Miami

mar. 11/11

7:10 am-5:05 pm

1 stop9h 55m

$179

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

sáb. 11/15

1:25 pm-9:40 pm

2 stops8h 15m

Miami

mié. 11/19

7:40 am-5:05 pm

2 stops9h 25m

$180

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

mié. 12/3

10:35 am-9:50 pm

2 stops11h 15m

Miami

sáb. 12/6

6:05 am-4:50 pm

1 stop10h 45m

$190

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 24 results
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Best time to book a flight from Charleston to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Key Largo

How far ahead should I book a flight from Charleston to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Charleston to Key Largo. Price data was last updated on August 29, 2025.

The best time to book flights from Charleston to Key Largo is 47 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Charleston to Key Largo?

Currently, September is the cheapest month in which you can book a flight from Charleston to Key Largo (average of $232). Flying from Charleston to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to KE9?

Find hourly flight availability from Charleston to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

When flying from Charleston to Key Largo, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Charleston to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Charleston to Key Largo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Charleston to Key Largo flight should consider departing on Tuesday at noon when fares are most often at their lowest. Thursday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Charleston to Key Largo

Explore weekly flight availability from Charleston to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated septiembre 11, 2025.

The most flights from CHS to KE9 are scheduled on a Monday (4 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (4 on average).

How much does it cost to fly round-trip from Charleston to Key Largo?

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated septiembre 11, 2025.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Charleston to Key Largo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,960 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
JetBlue
7.2
Good
2,913 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,023 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Charleston to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Key Largo?

    Located just 10.2 mi from the city center, Charleston is the airport most travelers will use when flying to Key Largo from Charleston. Booking flights from Charleston (CHS) to Key Largo should be relatively easy as there are 4 daily outbound flights to Key Largo from 5 different airlines.

  • How popular is this Charleston to Key Largo flight route?

    This flight path from Charleston to Key Largo was viewed by 7 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Charleston to Key Largo?

    Airlines like American Airlines and Delta fly from Charleston to Key Largo in about 1h 38m. The time it takes to get you to your destination can typically vary by up to 4h 13m. There are 490 mi between Charleston and Key Largo. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most reliable airlines from Charleston to Key Largo?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Charleston to Key Largo on time: Envoy Air (82%), Qatar Airways (71%), American Airlines (70%).

  • What are the cheapest flights from Charleston to Key Largo?

    While on average a flight from Charleston to Key Largo is generally $776, our data shows the cheapest flight currently is $94. When looking at the most popular route, (Charleston - Miami), you can expect to pay $145 for that flight.

  • Can I find deals for flights from Charleston to Key Largo that include hotel bookings?

    Yes. In addition to deals on Charleston to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Key Largo.

  • Can I find deals for business class flights from Charleston to Key Largo?

    Yes. Cheapflights offers flight deals from Charleston to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Key Largo?

    Currently, September is the cheapest month in which you can book a flight from Charleston to Key Largo (average of $232). Flying from Charleston to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Charleston to Key Largo

Discover the top 5 airlines that operate flights from Charleston to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$40Average$111FlexibilityNo cancel feeOn-time65%
JetBlueCheapest$83Average$205FlexibilityNo cancel feeOn-time62%
DeltaCheapest$156Average$402FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$181Average$372FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$254Average$360FlexibilityNo cancel feeOn-time63%

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