HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Key Largo

$49+ Cheap flights from Charleston (CHS) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MIA
dez 6 — dez 131
sáb 12/6
sáb 12/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charleston to Key Largo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Charleston to Key Largo are usually found in August or September, booked 67 days in advance, depart on a Wednesday or Thursday and return on a Saturday

Cheap flight deals from Charleston to Key Largo

Keep the following information in mind while searching for Charleston to Key Largo flight deals. Data was last updated novembro 6, 2025.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$153
(Kiwi.com)

One-way from

$49
(American Airlines)

Popular in

December

Cheapest in

August

Average price

$287
Provider with most accurate pricing for Charleston-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Miami flights.
Search Deals
From Charleston to Key Largo
Search Deals
One-way flight from Charleston to Key Largo
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($5 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from Charleston to Key Largo

Cheapest flights from Charleston to Key Largo
Explore the most affordable flight options available from Charleston to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on novembro 6, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 11/226:15 pmCHS - MIA
1 stop15h 01mMultiple Airlines
seg 11/249:40 pmMIA - CHS
1 stop9h 46mMultiple Airlines
Deal found 11/3$153
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 12/38:31 amCHS - MIA
1 stop24h 51mMultiple Airlines
qua 12/109:03 pmMIA - CHS
1 stop13h 57mMultiple Airlines
Deal found 11/5$154
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 12/228:06 pmCHS - MIA
Nonstop1h 53mAmerican Airlines
sex 12/2610:56 pmMIA - CHS
Nonstop1h 49mAmerican Airlines
Deal found 11/3$156
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 12/86:31 pmCHS - MIA
1 stop6h 15mDelta
sex 12/127:30 pmMIA - CHS
1 stop4h 20mDelta
Deal found 11/6$157
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 12/43:18 pmCHS - MIA
1 stop6h 27mMultiple Airlines
qui 12/119:03 pmMIA - CHS
1 stop13h 57mMultiple Airlines
Deal found 11/5$161
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 11/186:11 pmCHS - MIA
1 stop15h 01mMultiple Airlines
qua 11/1910:15 pmMIA - CHS
1 stop9h 11mMultiple Airlines
Deal found 11/5$172
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/169:25 amCHS - MIA
Nonstop1h 49mAmerican Airlines
qui 12/183:28 pmMIA - CHS
1 stop6h 43mAmerican Airlines
Deal found 11/6$174
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 12/711:55 amCHS - MIA
1 stop21h 27mMultiple Airlines
sex 12/122:19 pmMIA - CHS
1 stop20h 41mMultiple Airlines
Deal found 11/4$175
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 12/611:55 amCHS - MIA
1 stop21h 27mMultiple Airlines
sex 12/125:30 amMIA - CHS
2 stops15h 24mMultiple Airlines
Deal found 11/4$177
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 11/239:12 amCHS - MIA
1 stop11h 37mMultiple Airlines
ter 12/212:41 pmMIA - CHS
1 stop18h 45mMultiple Airlines
Deal found 11/4$181
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 12/36:00 amCHS - MIA
Nonstop1h 44mAmerican Airlines
sáb 12/139:30 amMIA - CHS
1 stop6h 05mAmerican Airlines
Deal found 11/5$182

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated novembro 6, 2025.
Use the filters below to find and compare flights from Charleston to Key Largo that are best for you.

Fly from

Charleston

Fly to

Key Largo

Route

Depart

Return

Price

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

seg 2/9

5:18 pm-10:48 pm

1 stop5h 30m

Miami

qua 2/11

1:21 pm-7:18 pm

1 stop5h 57m

$157

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

sex 12/5

6:31 pm-12:46 am

1 stop6h 15m

Miami

sex 12/12

7:30 pm-11:50 pm

1 stop4h 20m

$157

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

ter 12/9

9:00 am-1:06 pm

1 stop4h 06m

Miami

qui 12/11

3:50 pm-9:48 pm

1 stop5h 58m

$157

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

ter 12/16

10:40 am-3:50 pm

1 stop5h 10m

Miami

qui 12/18

7:00 am-11:45 am

1 stop4h 45m

$157

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

seg 12/8

6:30 am-11:21 am

1 stop4h 51m

Miami

sex 12/12

6:30 pm-11:50 pm

1 stop5h 20m

$157

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

sex 12/12

5:38 pm-11:52 pm

1 stop6h 14m

Miami

ter 12/16

7:03 am-8:45 am

Nonstop1h 42m

$190

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

ter 1/6

6:00 am-10:58 am

1 stop4h 58m

Miami

seg 1/26

10:08 pm-11:55 pm

Nonstop1h 47m

$192

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

sex 12/5

11:55 am-3:03 pm

1 stop27h 08m

Miami

dom 12/14

8:53 pm-11:00 am

1 stop14h 07m

$201

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

seg 11/24

3:47 pm-8:46 pm

1 stop4h 59m

Miami

ter 12/2

2:11 pm-7:08 pm

1 stop4h 57m

$212

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

sex 12/12

5:15 pm-11:25 pm

1 stop6h 10m

Miami

ter 12/16

1:30 pm-7:55 pm

1 stop6h 25m

$217

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 21 results
1
2
3

Best time to book a flight from Charleston to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Key Largo

How far ahead should I book a flight from Charleston to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Charleston to Key Largo. Price data was last updated on October 31, 2025.

The best time to book flights from Charleston to Key Largo is 67 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Charleston to Key Largo?

Currently, March is the cheapest month in which you can book a flight from Charleston to Key Largo (average of $33). Flying from Charleston to Key Largo in June is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to KE9?

Find hourly flight availability from Charleston to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated novembro 6, 2025.

A simple way to save on the total cost of your ticket is to fly from Charleston to Key Largo in the morning. If you’re flexible enough to do this you can expect to save up to 39% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from Charleston to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Charleston to Key Largo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Charleston to Key Largo flight should consider departing on Saturday at noon when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Charleston to Key Largo

Explore weekly flight availability from Charleston to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated novembro 6, 2025.

The most flights from CHS to KE9 are scheduled on a Thursday (7 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (4 on average).

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated novembro 6, 2025.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Charleston to Key Largo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,238 reviews

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,238 reviews
Southwest
8.0
Very good
4,238 reviews

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,005 reviews
Southwest
8.0
Very good
4,238 reviews

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,041 reviews
Southwest
8.0
Very good
4,238 reviews

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
JetBlue
7.2
Good
2,907 reviews
Southwest
8.0
Very good
4,238 reviews

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,114 reviews
Southwest
8.0
Very good
4,238 reviews

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Charleston to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Key Largo?

    Located just 10.2 mi from the city center, Charleston is the airport most travelers will use when flying to Key Largo from Charleston. Booking flights from Charleston (CHS) to Key Largo should be relatively easy as there are 5 daily outbound flights to Key Largo from 6 different airlines.

  • How popular is this Charleston to Key Largo flight route?

    This flight path from Charleston to Key Largo was viewed by 10 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Charleston to Key Largo?

    Airlines like Delta fly from Charleston to Key Largo in about 5h 30m. The time it takes to get you to your destination can typically vary by up to . There are 490 mi between Charleston and Key Largo.

  • What are the cheapest airlines to fly from Charleston to Key Largo one-way?

    One-way options have recently been found by users for as low as $59 on American Airlines. Other airlines that offer cheap prices include Southwest from $76 and Delta from $79 one-way.

  • What are the most reliable airlines from Charleston to Key Largo?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Charleston to Key Largo on time: Envoy Air (99%), American Airlines (67%), Qatar Airways (67%).

  • What are the cheapest flights from Charleston to Key Largo?

    While on average a flight from Charleston to Key Largo is generally $368, our data shows the cheapest flight currently is $68. When looking at the most popular route, (Charleston - Miami), you can expect to pay $144 for that flight.

  • Can I find deals for flights from Charleston to Key Largo that include hotel bookings?

    Yes. In addition to deals on Charleston to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Key Largo.

  • Can I find deals for business class flights from Charleston to Key Largo?

    Yes. Cheapflights offers flight deals from Charleston to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Key Largo?

    Currently, March is the cheapest month in which you can book a flight from Charleston to Key Largo (average of $33). Flying from Charleston to Key Largo in June is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charleston to Key Largo

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Orlando flights
Charlotte to Miami flights
Charlotte to Fort Lauderdale flights
Charleston to Fort Lauderdale flights
Charleston to Miami flights
Charlotte to Tampa flights
Charlotte to Fort Myers flights
Charlotte to Sarasota flights
Charlotte to West Palm Beach flights
Charlotte to Key West flights
Greenville to Miami flights
Charlotte to Jacksonville flights
Columbia to Orlando flights
Charleston to Tampa flights
Savannah to Miami flights
Columbia to Miami flights
Myrtle Beach to Fort Lauderdale flights
Myrtle Beach to Miami flights
Myrtle Beach to Orlando flights
Charleston to West Palm Beach flights
Charlotte to Tallahassee flights
Charleston to Orlando flights
Columbia to Fort Lauderdale flights
Charlotte to Panama City flights
Greenville to Orlando flights
Greenville to Tampa flights
Charlotte to Pensacola flights
Columbia to West Palm Beach flights
Greenville to Fort Lauderdale flights
Columbia to Tampa flights
Charleston to Key West flights
Charlotte to Melbourne flights
Charlotte to Orlando Sanford Intl flights
Greenville to West Palm Beach flights
Myrtle Beach to Tampa flights
Augusta to Fort Lauderdale flights
Charlotte to Valparaiso flights
Myrtle Beach to Key West flights
Myrtle Beach to Fort Myers flights
Greenville to Pensacola flights
Charleston to Sarasota flights
Charlotte to Daytona Beach flights
Greenville to Sarasota flights
Augusta to Miami flights
Savannah to Fort Myers flights
Savannah to Tampa flights
Charleston to Pensacola flights
Columbia to Sarasota flights
Savannah to Fort Lauderdale flights
Augusta to Orlando flights

Top 6 airlines flying from Charleston to Key Largo

Discover the top 6 airlines that operate flights from Charleston to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated novembro 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$41Average$107FlexibilityNo cancel feeOn-time65%
JetBlueCheapest$90Average$204FlexibilityNo cancel feeOn-time62%
Breeze AirwaysCheapest$110Average$220FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$156Average$388FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$182Average$369FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$245Average$370FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
Cookie settings©2025 Cheapflights