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Key Largo

$90+ Cheap flights from Charleston (CHS) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/9. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MIA
Apr 25 — May 21
Sat 4/25
Sat 5/2
1 adult, Economy
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Cheapflights Tip: The best prices from Charleston to Key Largo are usually found in August or September, booked 47 days in advance, depart on a Friday or Thursday and return on a Wednesday

Cheap flight deals from Charleston to Key Largo

Cheapest flights from Charleston to Key Largo
Explore the most affordable flight options available from Charleston to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.

This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:40 am
CHS
-
MIA
1 stop6h 00m
Southwest
Tue 4/2812:10 pm
MIA
-
CHS
1 stop6h 25m
Southwest
Deal found 3/22$198
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:05 pm
CHS
-
MIA
1 stop24h 59m
Spirit Airlines
Tue 4/214:05 pm
MIA
-
CHS
1 stop19h 03m
Spirit Airlines
Deal found 3/25$205
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:40 am
CHS
-
MIA
2 stops10h 50m
Southwest
Tue 5/127:20 am
MIA
-
CHS
2 stops12h 40m
Southwest
Deal found 3/23$209
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:00 am
CHS
-
MIA
Nonstop1h 40m
American Airlines
Tue 4/288:49 am
MIA
-
CHS
1 stop7h 44m
American Airlines
Deal found 3/24$213
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:40 am
CHS
-
MIA
1 stop6h 35m
Southwest
Sat 5/96:35 am
MIA
-
CHS
1 stop7h 30m
Southwest
Deal found 3/24$217
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:00 am
CHS
-
MIA
2 stops10h 00m
Southwest
Wed 5/612:10 pm
MIA
-
CHS
1 stop5h 30m
Southwest
Deal found 3/23$222
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:04 pm
CHS
-
MIA
1 stop7h 12m
Multiple Airlines
Thu 4/167:21 pm
MIA
-
CHS
2 stops26h 32m
Multiple Airlines
Deal found 3/23$223
This Expedia deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:10 pm
CHS
-
MIA
1 stop6h 41m
Frontier
Sat 4/49:39 pm
MIA
-
CHS
1 stop11h 48m
Frontier
Deal found 3/25$230

Find flight deals from Charleston to Key Largo

Keep the following information in mind while searching for Charleston to Key Largo flight deals. Data was last updated March 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$198
(Southwest)

One-way from

$90
(Frontier)

Popular in

March

Cheapest in

August

Average price

$345
Provider with most accurate pricing for Charleston-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Miami flights.
Search Deals
From Charleston to Key Largo
Search Deals
One-way flight from Charleston to Key Largo
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($21 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
Use the filters below to find and compare flights from Charleston to Key Largo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Wed 5/6

12:00 pm-9:55 pm

2 stops9h 55m

Miami

Wed 5/13

12:10 pm-8:00 pm

1 stop7h 50m

$204

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Mon 5/11

6:00 am-3:20 pm

1 stop9h 20m

Miami

Tue 5/12

12:35 pm-8:25 pm

1 stop7h 50m

$241

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Mon 5/4

6:00 am-3:20 pm

1 stop9h 20m

Miami

Wed 5/6

12:10 pm-5:40 pm

1 stop5h 30m

$241

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Wed 6/10

3:00 pm-9:20 pm

1 stop6h 20m

Miami

Wed 7/15

7:40 am-4:10 pm

2 stops8h 30m

$253
Quickest round-trip

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Tue 4/14

2:20 pm-6:35 pm

1 stop4h 15m

Miami

Thu 4/16

7:41 pm-12:22 am

1 stop4h 41m

$277

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Thu 5/7

8:05 am-2:30 pm

1 stop6h 25m

Miami

Sun 5/10

7:00 am-2:25 pm

1 stop7h 25m

$310

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Sat 5/2

11:15 am-5:15 pm

1 stop6h 00m

Miami

Thu 5/7

6:20 am-6:20 pm

2 stops12h 00m

$340

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Thu 5/14

4:45 pm-11:00 pm

1 stop6h 15m

Miami

Mon 5/18

6:40 am-1:35 pm

1 stop6h 55m

$347

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Sat 5/30

6:03 pm-12:48 am

1 stop6h 45m

Miami

Sat 6/6

7:39 pm-11:59 pm

1 stop4h 20m

$348
Cheapest one-way

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Sat 4/25

8:00 am-7:40 pm

1 stop11h 40m

$124

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/26

Showing 1-10 of 21 resultsSorted by cheapest first
1
2
3

Best time to book a flight from Charleston to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Key Largo

How far ahead should I book a flight from Charleston to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Charleston to Key Largo. Price data was last updated on March 13, 2026.

The best time to book flights from Charleston to Key Largo is 47 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Charleston to Key Largo?

Currently, December is the cheapest month in which you can book a flight from Charleston to Key Largo (average of $33). Flying from Charleston to Key Largo in June is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to KE9?

Find hourly flight availability from Charleston to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 26, 2026.

A simple way to save on the total cost of your ticket is to fly from Charleston to Key Largo in the afternoon. If you’re flexible enough to do this you can expect to save up to 69% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from Charleston to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Charleston to Key Largo. Price data was last updated on March 23, 2026.

Travelers seeking maximum savings on their Charleston to Key Largo flight should consider departing on Tuesday at noon when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Charleston to Key Largo

Explore weekly flight availability from Charleston to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 26, 2026.

The most flights from CHS to KE9 are scheduled on a Tuesday (7 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (3 on average).

How much does it cost to fly round-trip from Charleston to Key Largo?

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated March 26, 2026.
Read reviews from past customers who have flown Southwest,Delta, andJetBlue from Charleston to Key Largo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,331 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,331 reviews
Southwest
8.0
Very good
4,331 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,336 reviews
Southwest
8.0
Very good
4,331 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
JetBlue
7.2
Good
2,905 reviews
Southwest
8.0
Very good
4,331 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,496 reviews
Southwest
8.0
Very good
4,331 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Spirit Airlines
6.3
Okay
8,546 reviews
Southwest
8.0
Very good
4,331 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Key Largo?

    Located just 10.2 mi from the city center, Charleston is the airport most travelers will use when flying to Key Largo from Charleston. Booking flights from Charleston (CHS) to Key Largo should be relatively easy as there are 5 daily outbound flights to Key Largo from 6 different airlines.

  • How popular is this Charleston to Key Largo flight route?

    This flight path from Charleston to Key Largo was viewed by 19 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Charleston to Key Largo?

    Airlines like Southwest and Delta fly from Charleston to Key Largo in about 4h 15m. The time it takes to get you to your destination can typically vary by up to 5h 40m. There are 490 mi between Charleston and Key Largo. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Charleston to Key Largo one-way?

    One-way options have recently been found by users for as low as $31 on Spirit Airlines. Other airlines that offer cheap prices include JetBlue from $69 and Southwest from $74 one-way.

  • What are the most reliable airlines from Charleston to Key Largo?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Charleston to Key Largo on time: British Airways (77%), Republic Airways (75%), American Airlines (61%).

  • What are the cheapest flights from Charleston to Key Largo?

    While on average a flight from Charleston to Key Largo is generally $804, our data shows the cheapest flight currently is $134. When looking at the most popular route, (Charleston - Miami), you can expect to pay $198 for that flight.

  • Can I find deals for flights from Charleston to Key Largo that include hotel bookings?

    Yes. In addition to deals on Charleston to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Key Largo.

  • Can I find deals for business class flights from Charleston to Key Largo?

    Yes. Cheapflights offers flight deals from Charleston to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Key Largo?

    Currently, December is the cheapest month in which you can book a flight from Charleston to Key Largo (average of $33). Flying from Charleston to Key Largo in June is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 6 airlines flying from Charleston to Key Largo

Discover the top 6 airlines that operate flights from Charleston to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$43Average$98FlexibilityNo cancel feeOn-time65%
JetBlueCheapest$81Average$196FlexibilityNo cancel feeOn-time62%
Breeze AirwaysCheapest$110Average$220FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$113Average$375FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$160Average$343FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$245Average$339FlexibilityNo cancel feeOn-time63%

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