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Italy

$268+ Cheap flights from Missouri to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.
STL — NAP
Mar 21 — Mar 281
Sat 3/21
Sat 3/28
1 adult, Economy
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Cheap flight deals from Missouri to Italy

Cheapest flights from Missouri to Italy
Explore the most affordable flight options available from Missouri to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 19, 2026.

This Mytrip deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/224:05 pm
STL
-
MXP
1 stop11h 55m
Air Canada
Tue 3/1012:05 pm
MXP
-
STL
2 stops33h 24m
Air Canada
Deal found 2/15$471
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:45 am
STL
-
MXP
1 stop22h 35m
United Airlines
Wed 4/2212:20 pm
MXP
-
STL
2 stops40h 27m
United Airlines
Deal found 2/17$473
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am
MCI
-
MXP
1 stop24h 05m
United Airlines
Fri 11/201:05 pm
MXP
-
MCI
2 stops34h 19m
United Airlines
Deal found 2/18$473
This United Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:40 am
STL
-
MXP
2 stops19h 15m
United Airlines
Wed 3/2512:05 pm
MXP
-
STL
2 stops39h 45m
United Airlines
Deal found 2/16$475
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1011:28 am
STL
-
MXP
1 stop14h 02m
United Airlines
Wed 3/2512:05 pm
MXP
-
STL
2 stops39h 45m
United Airlines
Deal found 2/18$479
This Air Canada deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am
MCI
-
MXP
2 stops20h 55m
Air Canada
Fri 11/201:05 pm
MXP
-
MCI
3 stops36h 37m
Air Canada
Deal found 2/18$481
This Air Canada deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:00 pm
STL
-
MXP
2 stops31h 55m
Air Canada
Thu 3/2612:05 pm
MXP
-
STL
2 stops39h 18m
Air Canada
Deal found 2/15$482
This Cheapflightsfares deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:49 pm
STL
-
MXP
2 stops14h 51m
Lufthansa
Wed 8/266:00 am
MXP
-
STL
2 stops17h 26m
Lufthansa
Deal found 2/15$485
This Air Canada deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/84:05 pm
STL
-
MXP
2 stops34h 50m
Air Canada
Wed 3/2512:05 pm
MXP
-
STL
2 stops39h 10m
Air Canada
Deal found 2/18$486
This Air Canada deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:36 pm
MCI
-
MXP
3 stops32h 44m
Air Canada
Thu 8/2012:20 pm
MXP
-
MCI
3 stops43h 17m
Air Canada
Deal found 2/15$486
This Air Canada deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:41 am
STL
-
MXP
3 stops43h 14m
Air Canada
Thu 3/2612:05 pm
MXP
-
STL
2 stops40h 54m
Air Canada
Deal found 2/15$487
This Cheapflightsfares deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:49 pm
STL
-
LIN
2 stops15h 56m
Lufthansa
Wed 8/266:50 am
LIN
-
STL
2 stops16h 36m
Lufthansa
Deal found 2/15$488

Find flight deals from Missouri to Italy

Keep the following information in mind while searching for Missouri to Italy flight deals. Data was last updated February 19, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$471
(Mytrip)

One-way from

$268
(oojo)

Popular in

June

Cheapest in

February

Average price

$540
Provider with most accurate pricing for Lambert-St Louis-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Rome (ROM) flights.
Search Deals
From Missouri to Italy
Search Deals
One-way flight from Missouri to Italy
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($394 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($62 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 19, 2026.
Use the filters below to find and compare flights from Missouri to Italy that are best for you.

Fly from

Missouri

Fly to

Italy

Route

Depart

Return

Price

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Wed 3/18

7:40 am-8:55 am

2 stops19h 15m

Milan Malpensa

Wed 3/25

12:05 pm-9:50 pm

2 stops39h 45m

$475

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Wed 8/12

5:00 am-10:20 am

2 stops22h 20m

Milan Malpensa

Wed 8/26

12:20 pm-2:18 pm

2 stops32h 58m

$476

St. LouisMilan

STL - LIN

STLLIN

Lambert-St Louis

Wed 4/15

12:55 pm-1:25 pm

2 stops17h 30m

Milan Linate

Wed 4/22

1:40 pm-7:30 pm

1 stop12h 50m

$493

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Fri 8/14

6:49 pm-1:20 pm

1 stop11h 31m

Milan Malpensa

Fri 8/28

3:20 pm-12:29 am

1 stop16h 09m

$493

Kansas CityMilan

MCI - MXP

MCIMXP

Kansas City

Wed 8/12

6:00 am-10:35 am

2 stops21h 35m

Milan Malpensa

Wed 8/26

12:20 pm-8:52 pm

2 stops39h 32m

$493

Kansas CityVenice

MCI - VCE

MCIVCE

Kansas City

Wed 4/15

6:06 pm-5:50 pm

2 stops16h 44m

Venice Marco Polo

Wed 4/22

12:15 pm-11:59 pm

2 stops18h 44m

$495

Kansas CityMilan

MCI - MXP

MCIMXP

Kansas City

Wed 8/12

2:15 pm-5:35 pm

2 stops20h 20m

Milan Malpensa

Wed 8/26

9:00 am-7:13 pm

1 stop17h 13m

$497

Kansas CityMilan

MCI - MXP

MCIMXP

Kansas City

Wed 8/12

3:36 pm-9:25 am

1 stop34h 49m

Milan Malpensa

Wed 8/26

9:00 am-7:13 pm

1 stop17h 13m

$498

St. LouisMilan

STL - LIN

STLLIN

Lambert-St Louis

Sun 2/22

9:35 am-3:45 pm

2 stops23h 10m

Milan Linate

Tue 3/10

7:55 am-11:44 pm

2 stops21h 49m

$500

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Wed 8/12

5:45 pm-5:35 pm

2 stops16h 50m

Milan Malpensa

Wed 8/26

9:00 am-11:37 pm

2 stops21h 37m

$501

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/16

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Italy

What is the cheapest month to book a flight from Missouri to Italy?

Currently, March is the cheapest month in which you can book a flight from Missouri to Italy (average of $441). Flying from Missouri to Italy in June is currently the most expensive (average of $1,007). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Italy?

    For as low as $495, United Airlines can have you in Italy from Missouri in 16h 44m. Airlines will cover a distance of 5039 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Italy one-way?

    $265 is the cheapest one-way deal found within the past few days, from Lufthansa. You may also be able to find cheap deals on United Airlines and Delta, with prices starting from $287 and $312, respectively.

  • Can I find deals for flights from Missouri to Italy that include hotel bookings?

    Yes. In addition to deals on Missouri to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Italy.

  • Can I find deals for business class flights from Missouri to Italy?

    Yes. Cheapflights offers flight deals from Missouri to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Italy?

    Currently, March is the cheapest month in which you can book a flight from Missouri to Italy (average of $441). Flying from Missouri to Italy in June is currently the most expensive (average of $1,007). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 9 airlines flying from Missouri to Italy

Discover the top 9 airlines that operate flights from Missouri to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 19, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$472Average$955FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$485Average$1,068FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$490Average$1,136FlexibilityNo cancel feeOn-time76%
DeltaCheapest$498Average$1,083FlexibilityNo cancel feeOn-timeN/A
KLMCheapest$506Average$886FlexibilityNo cancel feeOn-time75%
Air CanadaCheapest$552Average$1,009FlexibilityNo cancel feeOn-time67%
American AirlinesCheapest$559Average$1,150FlexibilityNo cancel feeOn-time71%
Air FranceCheapest$655Average$1,282FlexibilityNo cancel feeOn-time77%
IberiaCheapest$692Average$1,323FlexibilityNo cancel feeOn-time77%

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