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Italy

$268+ Cheap flights from Missouri to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/20. Fares are subject to change and may not be available on all flights or dates of travel.
STL — NAP
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
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Cheap flight deals from Missouri to Italy

Keep the following information in mind while searching for Missouri to Italy flight deals. Data was last updated January 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$400
(Ticket)

One-way from

$268
(oojo)

Popular in

June

Cheapest in

January

Average price

$693
Provider with most accurate pricing for Lambert-St Louis-Rome (ROM) flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Rome (ROM) flights.
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From Missouri to Italy
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One-way flight from Missouri to Italy
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Highest demand for flights based on searches. 27% potential increase in price ($360 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($55 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Missouri to Italy

Cheapest flights from Missouri to Italy
Explore the most affordable flight options available from Missouri to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This Air Canada deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/108:00 amMCI - MXP
2 stops18h 55mAir Canada
Tue 3/2412:05 pmMXP - MCI
2 stops30h 14mAir Canada
Deal found 1/8$425
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2011:32 amMCI - FCO
2 stops17h 53mLufthansa
Fri 2/279:45 amFCO - MCI
1 stop19h 14mLufthansa
Deal found 1/7$426
This United Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/104:25 pmMCI - MXP
2 stops34h 30mUnited Airlines
Fri 2/201:05 pmMXP - MCI
2 stops33h 40mUnited Airlines
Deal found 1/7$431
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2011:32 amMCI - FCO
2 stops17h 53mMultiple Airlines
Fri 2/2711:00 amFCO - MCI
1 stop16h 06mMultiple Airlines
Deal found 1/6$435
This oojo deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/121:50 pmMCI - MXP
2 stops16h 30mBritish Airways
Wed 8/262:20 pmMXP - MCI
1 stop34h 20mBritish Airways
Deal found 1/8$435
This oojo deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/96:44 pmSTL - BLQ
2 stops15h 51mBritish Airways
Mon 2/168:15 pmBLQ - STL
2 stops34h 33mBritish Airways
Deal found 1/7$436
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2111:27 amMCI - FCO
1 stop13h 18mLufthansa
Sat 2/289:40 amFCO - MCI
2 stops19h 19mLufthansa
Deal found 1/7$437
This United Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/257:41 amSTL - FCO
1 stop17h 04mUnited Airlines
Wed 3/41:15 pmFCO - STL
2 stops38h 52mUnited Airlines
Deal found 1/8$438
This United Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:45 pmMCI - FCO
1 stop12h 30mUnited Airlines
Tue 8/2511:30 amFCO - MCI
2 stops35h 33mUnited Airlines
Deal found 1/8$438
This FlightHub deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/106:30 pmMCI - MXP
2 stops19h 15mMultiple Airlines
Fri 2/201:05 pmMXP - MCI
2 stops33h 40mMultiple Airlines
Deal found 1/8$438
This Booking.com deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:00 amMCI - FCO
2 stops20h 15mAir Canada
Tue 8/2511:30 amFCO - MCI
2 stops34h 01mAir Canada
Deal found 1/8$441
This oojo deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/92:54 pmSTL - MXP
2 stops21h 56mBritish Airways
Tue 2/178:40 pmMXP - STL
2 stops34h 08mBritish Airways
Deal found 1/7$442

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Missouri to Italy that are best for you.

Fly from

Missouri

Fly to

Italy

Route

Depart

Return

Price

Kansas CityMilan

MCI - MXP

MCIMXP

Kansas City

Tue 3/10

8:00 am-8:55 am

2 stops18h 55m

Milan Malpensa

Tue 3/24

12:05 pm-12:19 pm

2 stops30h 14m

$425

Kansas CityMilan

MCI - MXP

MCIMXP

Kansas City

Tue 2/10

4:25 pm-9:55 am

2 stops34h 30m

Milan Malpensa

Fri 2/20

1:05 pm-3:45 pm

2 stops33h 40m

$431

Kansas CityRome

MCI - FCO

MCIFCO

Kansas City

Fri 2/20

11:32 am-7:45 am

1 stop13h 13m

Rome Fiumicino

Fri 2/27

11:00 am-8:06 pm

1 stop16h 06m

$435

St. LouisBologna

STL - BLQ

STLBLQ

Lambert-St Louis

Mon 2/9

6:44 pm-5:35 pm

2 stops15h 51m

Bologna Guglielmo Marconi

Mon 2/16

8:15 pm-11:48 pm

2 stops34h 33m

$436

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Tue 2/17

7:10 am-9:05 am

1 stop18h 55m

Milan Malpensa

Tue 2/24

11:05 am-11:36 pm

1 stop19h 31m

$442

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Tue 2/10

6:46 pm-7:45 pm

2 stops17h 59m

Milan Malpensa

Tue 2/17

8:40 pm-9:12 pm

2 stops31h 32m

$442

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Sun 2/8

5:20 pm-10:45 am

2 stops34h 25m

Milan Malpensa

Tue 2/17

8:40 pm-11:48 pm

2 stops34h 08m

$442

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Tue 1/27

12:44 pm-8:30 am

1 stop12h 46m

Rome Fiumicino

Tue 2/3

1:10 pm-2:30 pm

2 stops32h 20m

$443

Kansas CityVenice

MCI - VCE

MCIVCE

Kansas City

Mon 3/23

6:13 pm-8:20 pm

2 stops20h 07m

Venice Marco Polo

Mon 3/30

9:15 pm-10:28 pm

2 stops32h 13m

$444

Kansas CityVenice

MCI - VCE

MCIVCE

Kansas City

Tue 3/24

1:58 pm-7:30 pm

2 stops23h 32m

Venice Marco Polo

Mon 3/30

9:15 pm-10:49 pm

2 stops32h 34m

$444

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/6

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Italy

What is the cheapest month to book a flight from Missouri to Italy?

Currently, December is the cheapest month in which you can book a flight from Missouri to Italy (average of $255). Flying from Missouri to Italy in July is currently the most expensive (average of $863). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Italy?

    For as low as $435, Air Canada can have you in Italy from Missouri in 13h 13m. Airlines will cover a distance of 5199 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Italy one-way?

    $265 is the cheapest one-way deal found within the past few days, from Lufthansa. You may also be able to find cheap deals on United Airlines and Delta, with prices starting from $268 and $312, respectively.

  • Can I find deals for flights from Missouri to Italy that include hotel bookings?

    Yes. In addition to deals on Missouri to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Italy.

  • Can I find deals for business class flights from Missouri to Italy?

    Yes. Cheapflights offers flight deals from Missouri to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Italy?

    Currently, December is the cheapest month in which you can book a flight from Missouri to Italy (average of $255). Flying from Missouri to Italy in July is currently the most expensive (average of $863). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 9 airlines flying from Missouri to Italy

Discover the top 9 airlines that operate flights from Missouri to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$472Average$905FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$485Average$1,114FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$490Average$1,211FlexibilityNo cancel feeOn-time76%
DeltaCheapest$498Average$1,088FlexibilityNo cancel feeOn-timeN/A
IberiaCheapest$536Average$1,226FlexibilityNo cancel feeOn-time77%
KLMCheapest$555Average$930FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$594Average$1,161FlexibilityNo cancel feeOn-time71%
Air FranceCheapest$655Average$1,146FlexibilityNo cancel feeOn-time77%
Air CanadaCheapest$705Average$1,209FlexibilityNo cancel feeOn-time67%

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