What are the cheapest airlines to fly from Missouri to Italy one-way?

$451 is the cheapest one-way deal found within the past few days, from Air Canada. You may also be able to find cheap deals on Aer Lingus and Scandinavian Airlines, with prices starting from $472 and $496, respectively.

How far in advance should I book a flight from Missouri to Italy?

Travelers have found it’s best to book a flight 27 days in advance to save up to 88% compared to booking the same week of travel. As your travel date approaches, the cost of this flight route may potentially increase. While opting to book 27 days out may not be an option for all, there are still additional ways to secure a deal in the near future. You might find a flight from Missouri to Italy 1-2 weeks in advance for as low as $699, or $1,275 for flights within the next 24 hours.

What is the cheapest month to fly from Missouri to Italy?

November is one of the best times of the year to fly to Italy from Missouri. Prices for November average $1,092 per person but you can even find prices for as low as $594. The most expensive prices can be found in the month of June. Opting for a November flight can save you 44% on your journey compared to booking in June

Can I find deals for flights from Missouri to Italy that include hotel bookings?

Yes. In addition to deals on Missouri to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Italy?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Italy.

Can I find deals for business class flights from Missouri to Italy?

Yes. Cheapflights offers flight deals from Missouri to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$698+ Flights from Missouri to Italy

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Missouri to Italy with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Italy

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$563 (United Airlines)
One-way from	$297 (Kiwi.com)
Popular in	June
Cheapest in	November
Average price	$1,492

Provider with most accurate pricing for Kansas City-Rome (ROM) flight deals.

Search Deals

Provider most trusted by Cheapflights users for Kansas City-Rome (ROM) flights.

Search Deals

From Missouri to Italy

Search Deals

One-way flight from Missouri to Italy

Search Deals

Highest demand for flights based on searches. 24% potential increase in price ($356 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($45 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in May 2025

Search Deals

Find flight deals from Missouri to Italy

Cheapest flights from Missouri to Italy
Explore the most affordable flight options available from Missouri to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Thu 11/66:45 amSTL - MXP

2 stops17h 40mDelta

Tue 11/1811:05 amMXP - STL

1 stop19h 34mDelta

Deal found 4/30

$543

Tue 10/71:30 pmSTL - MXP

1 stop13h 30mUnited Airlines

Wed 10/2212:15 pmMXP - STL

2 stops34h 23mUnited Airlines

Deal found 4/30

$563

Sun 11/234:19 pmMCI - VCE

2 stops17h 36mAmerican Airlines

Fri 12/56:20 amVCE - MCI

2 stops20h 57mAmerican Airlines

Deal found 4/30

$565

Tue 10/76:35 amSTL - MXP

2 stops20h 25mAir Canada

Wed 10/2212:15 pmMXP - STL

2 stops33h 04mAir Canada

Deal found 4/30

$568

Mon 11/102:49 pmSTL - FCO

1 stop11h 11mIberia

Tue 11/256:55 pmFCO - STL

2 stops33h 46mIberia

Deal found 4/30

$582

Mon 11/106:43 amSTL - FCO

1 stop19h 17mAmerican Airlines

Tue 11/257:35 amFCO - STL

2 stops21h 06mAmerican Airlines

Deal found 4/30

$590

Sun 11/236:00 amMCI - VCE

2 stops19h 55mUnited Airlines

Fri 12/511:05 amVCE - MCI

1 stop14h 53mUnited Airlines

Deal found 4/30

$592

Mon 11/102:49 pmSTL - FCO

1 stop11h 11mMultiple Airlines

Tue 11/251:10 pmFCO - STL

1 stop14h 06mMultiple Airlines

Deal found 4/30

$604

Sun 11/238:00 amMCI - VCE

3 stops18h 45mAir Canada

Fri 12/56:50 amVCE - MCI

3 stops19h 41mAir Canada

Deal found 4/30

$628

Wed 10/86:40 amMCI - FLR

2 stops29h 10mScandinavian Airlines

Wed 10/2212:20 pmFLR - MCI

2 stops41h 01mScandinavian Airlines

Deal found 4/29

$636

Tue 11/44:15 pmSTL - FCO

1 stop11h 50mAir Canada

Tue 11/187:05 amFCO - STL

2 stops15h 21mAir Canada

Deal found 4/30

$645

Tue 11/44:15 pmSTL - FCO

1 stop11h 50mUnited Airlines

Tue 11/1812:55 pmFCO - STL

1 stop15h 15mUnited Airlines

Deal found 4/30

$646

Best flights from Missouri to Italy
Discover carefully curated flight deals from Missouri to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2025.

Tue 10/71:30 pmSTL - MXP

1 stop13h 30mUnited Airlines

Wed 10/2212:15 pmMXP - STL

2 stops34h 23mUnited Airlines

Deal found 4/30

$563

Tue 10/76:35 amSTL - MXP

2 stops20h 25mAir Canada

Wed 10/2212:15 pmMXP - STL

2 stops33h 04mAir Canada

Deal found 4/30

$568

Wed 10/86:40 amMCI - FLR

2 stops29h 10mScandinavian Airlines

Wed 10/2212:20 pmFLR - MCI

2 stops41h 01mScandinavian Airlines

Deal found 4/29

$636

Wed 7/25:07 pmMCI - NAP

1 stop12h 53mAmerican Airlines

Wed 9/33:00 pmNAP - MCI

1 stop15h 59mAmerican Airlines

Deal found 4/30

$699

Mon 10/137:30 amMCI - VCE

2 stops19h 10mMultiple Airlines

Mon 10/273:00 pmVCE - MCI

2 stops32h 21mMultiple Airlines

Deal found 4/30

$715

Tue 9/236:02 amMCI - VCE

1 stop20h 53mBritish Airways

Tue 10/1412:15 pmVCE - MCI

1 stop15h 35mBritish Airways

Deal found 4/30

$720

Mon 10/134:15 pmMCI - VCE

1 stop12h 40mDelta

Mon 10/2712:15 pmVCE - MCI

2 stops27h 30mDelta

Deal found 4/30

$732

Wed 8/66:24 pmMCI - MXP

2 stops16h 51mFinnair

Tue 8/197:05 pmMXP - MCI

2 stops31h 06mFinnair

Deal found 4/30

$752

Wed 10/16:17 pmMCI - FLR

2 stops18h 18mIberia

Fri 10/316:55 amFLR - MCI

2 stops19h 41mIberia

Deal found 4/29

$771

Mon 8/410:46 amSTL - MXP

1 stop15h 39mKLM

Fri 8/1511:40 amMXP - STL

1 stop18h 59mKLM

Deal found 4/30

$801

Wed 9/173:30 pmSTL - VCE

1 stop11h 40mLufthansa

Fri 9/266:00 amVCE - STL

1 stop14h 30mLufthansa

Deal found 4/30

$805

Fri 9/52:18 pmSTL - MXP

2 stops13h 12mAir France

Tue 9/1611:25 amMXP - STL

2 stops16h 24mAir France

Deal found 4/30

$893

Last-minute flights from Missouri to Italy
Discover last-minute flight deals from Missouri to Italy. Data last updated May 1, 2025 and is based on user searches.

Mon 5/52:02 pmMCI - FCO

2 stops21h 43mScandinavian Airlines

Fri 5/1611:55 amFCO - MCI

2 stops42h 41mScandinavian Airlines

Deal found 4/29

$1,217

Tue 5/67:00 amMCI - FCO

2 stops25h 30mMultiple Airlines

Fri 5/1611:35 amFCO - MCI

1 stop39h 37mMultiple Airlines

Deal found 4/29

$889

Tue 5/65:46 pmMCI - FCO

2 stops19h 04mAer Lingus

Fri 5/167:30 amFCO - MCI

2 stops31h 58mAer Lingus

Deal found 4/29

$952

Thu 5/81:30 pmSTL - MXP

1 stop13h 30mAir Canada

Wed 5/2112:15 pmMXP - STL

1 stop14h 43mAir Canada

Deal found 4/30

$793

Thu 5/87:30 amSTL - MXP

2 stops19h 30mMultiple Airlines

Wed 5/216:30 amMXP - STL

2 stops20h 28mMultiple Airlines

Deal found 4/30

$799

Fri 5/91:55 pmMCI - FLR

2 stops16h 00mUnited Airlines

Tue 5/1310:30 amFLR - MCI

2 stops29h 41mUnited Airlines

Deal found 4/30

$1,330

Fri 5/97:45 amMCI - FLR

3 stops18h 55mAir Canada

Tue 5/136:40 amFLR - MCI

3 stops20h 14mAir Canada

Deal found 4/30

$1,339

Sun 5/1110:31 amSTL - FCO

2 stops16h 54mAer Lingus

Sun 5/187:30 amFCO - STL

2 stops23h 21mAer Lingus

Deal found 4/30

$962

Sun 5/113:40 pmSTL - FCO

2 stops36h 25mScandinavian Airlines

Sat 5/2411:55 amFCO - STL

2 stops42h 43mScandinavian Airlines

Deal found 5/1

$1,402

Sun 5/116:00 amSTL - FCO

1 stop20h 00mBritish Airways

Sun 5/1811:05 amFCO - STL

1 stop18h 10mBritish Airways

Deal found 4/30

$1,578

Sun 5/111:38 pmSTL - FCO

1 stop12h 22mIberia

Sat 5/2410:00 amFCO - STL

1 stop16h 29mIberia

Deal found 4/30

$1,585

Sun 5/111:30 pmSTL - FCO

1 stop12h 45mAir Canada

Sat 5/2410:00 amFCO - STL

2 stops16h 58mAir Canada

Deal found 5/1

$1,623

One-way flights from Missouri to Italy
Search for one-way flight options from Missouri to Italy. Find affordable one-way fares based on user searches. Data last updated May 1, 2025.

Sat 7/128:08 pmMCI - FCO

2 stops35h 22mMultiple Airlines

Deal found 4/29

$297

Wed 7/165:40 pmSTL - FCO

2 stops48h 15mMultiple Airlines

Deal found 4/30

$300

Mon 6/305:47 pmSTL - MXP

2 stops47h 12mMultiple Airlines

Deal found 4/30

$382

Mon 6/301:30 pmSTL - MXP

1 stop13h 30mAir Canada

Deal found 4/30

$451

Wed 5/145:46 amMCI - FLR

3 stops33h 49mMultiple Airlines

Deal found 4/30

$469

Tue 10/77:23 amSTL - NAP

2 stops20h 17mAer Lingus

Deal found 4/30

$472

Tue 8/267:23 amSTL - VCE

2 stops21h 02mAer Lingus

Deal found 4/30

$482

Wed 5/149:07 pmMCI - VCE

3 stops56h 53mMultiple Airlines

Deal found 4/30

$490

Tue 9/231:45 pmMCI - VCE

2 stops37h 15mScandinavian Airlines

Deal found 4/30

$496

Wed 8/64:34 pmMCI - MXP

1 stop11h 46mAmerican Airlines

Deal found 4/29

$558

Thu 5/159:02 amMCI - NAP

2 stops18h 38mAer Lingus

Deal found 4/30

$558

Fri 8/81:30 pmSTL - MXP

1 stop13h 30mUnited Airlines

Deal found 4/30

$559

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Tue 10/7

1:30 pm-10:00 am

1 stop13h 30m

Milan Malpensa

Wed 10/22

12:15 pm-3:38 pm

2 stops34h 23m

$563

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Tue 10/7

6:35 am-10:00 am

2 stops20h 25m

Milan Malpensa

Wed 10/22

12:15 pm-2:19 pm

2 stops33h 04m

$568

Kansas CityFlorence

MCI - FLR

MCIFLR

Kansas City

Wed 10/8

6:40 am-6:50 pm

2 stops29h 10m

Florence Peretola

Wed 10/22

12:20 pm-10:21 pm

2 stops41h 01m

$636

St. LouisVenice

STL - VCE

STLVCE

Lambert-St Louis

Tue 10/14

1:30 pm-9:40 am

1 stop13h 10m

Venice Marco Polo

Wed 10/29

11:05 am-9:10 pm

1 stop16h 05m

$663

St. LouisRome

STL - FCO

STLFCO

Lambert-St Louis

Mon 9/22

8:26 am-9:10 am

1 stop17h 44m

Rome Fiumicino

Wed 10/1

11:05 am-8:23 pm

1 stop16h 18m

$685

St. LouisNaples

STL - NAP

STLNAP

Lambert-St Louis

Wed 9/17

6:25 am-10:00 am

1 stop20h 35m

Naples

Wed 10/1

12:00 pm-8:21 pm

1 stop15h 21m

$695

St. LouisNaples

STL - NAP

STLNAP

Lambert-St Louis

Tue 8/12

1:15 pm-10:00 am

1 stop13h 45m

Naples

Tue 8/26

12:00 pm-9:05 pm

1 stop16h 05m

$699

Kansas CityNaples

MCI - NAP

MCINAP

Kansas City

Wed 7/2

5:07 pm-1:00 pm

1 stop12h 53m

Naples

Wed 9/3

3:00 pm-11:59 pm

1 stop15h 59m

$699

Kansas CityVenice

MCI - VCE

MCIVCE

Kansas City

Wed 5/14

12:12 pm-11:25 am

2 stops16h 13m

Venice Marco Polo

Wed 5/21

12:15 pm-9:31 pm

1 stop16h 16m

$702

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Mon 9/8

3:30 pm-7:15 pm

2 stops20h 45m

Milan Malpensa

Mon 9/15

3:30 pm-11:39 pm

2 stops39h 09m

$704

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 60 results

...

Best time to book a flight from Missouri to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Italy

What is the cheapest month to book a flight from Missouri to Italy?

Currently, January is the cheapest month in which you can book a flight from Missouri to Italy (average of $703). Flying from Missouri to Italy in June is currently the most expensive (average of $1,238). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to IT?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Italy as you normally would.

Rainfall in Italy by month

In terms of precipitation, rainfall in Italy ranges from 0.6 - 4.4 inches per month. November is typically the wettest month, when rainfall can reach 4.4 in. June is typically the driest time to visit Italy when rainfall is around 0.6 in.

Temperature in Italy by month

If weather is an important factor for your trip to Italy, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Italy

Peruse reviews from past customers who have flown with Delta, KLM and Austrian Airlines from Missouri to Italy to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,934 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

KLM

7.8

Good

1,334 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Austrian Airlines

7.6

Good

781 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Finnair

7.6

Good

1,275 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Air France

7.4

Good

1,446 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What are the cheapest airlines to fly from Missouri to Italy one-way?
$451 is the cheapest one-way deal found within the past few days, from Air Canada. You may also be able to find cheap deals on Aer Lingus and Scandinavian Airlines, with prices starting from $472 and $496, respectively.
Can I find deals for flights from Missouri to Italy that include hotel bookings?
Yes. In addition to deals on Missouri to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Italy?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Italy.
Can I find deals for business class flights from Missouri to Italy?
Yes. Cheapflights offers flight deals from Missouri to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Italy?
Currently, January is the cheapest month in which you can book a flight from Missouri to Italy (average of $703). Flying from Missouri to Italy in June is currently the most expensive (average of $1,238). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 8 airlines flying from Missouri to Italy

Airline	Cheapest	Average	Flexibility	On-time
KLM	Cheapest$573	Average$1,040	FlexibilityNo cancel fee	On-time75%
Lufthansa	Cheapest$606	Average$1,293	FlexibilityNo cancel fee	On-time76%
Delta	Cheapest$643	Average$1,086	FlexibilityNo cancel fee	On-timeN/A
British Airways	Cheapest$672	Average$1,085	FlexibilityNo cancel fee	On-time70%
Iberia	Cheapest$681	Average$1,176	FlexibilityNo cancel fee	On-time77%
United Airlines	Cheapest$686	Average$1,183	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$694	Average$1,203	FlexibilityNo cancel fee	On-time71%
Air Canada	Cheapest$705	Average$1,435	FlexibilityNo cancel fee	On-time67%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$297+ Cheap flights from Missouri to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/12. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Missouri to Italy with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Missouri to Italy

Keep the following information in mind while searching for Missouri to Italy flight deals. Data was last updated May 1, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Missouri to Italy

Cheapest flights from Missouri to ItalyExplore the most affordable flight options available from Missouri to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Explore the most affordable flight options available from Missouri to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Italy that are best for you.

Best time to book a flight from Missouri to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Italy

What is the cheapest month to book a flight from Missouri to Italy?

What is the cheapest time of day to fly from MO to IT?

Find hourly flight availability from Missouri to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Rainfall in Italy by month

Plan your trip to Italy by taking into account the average rainfall totals by month.

Temperature in Italy by month

Plan your trip to Italy by taking into account the average temperature totals by month.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated May 1, 2025.

Peruse reviews from past customers who have flown with Delta, KLM and Austrian Airlines from Missouri to Italy to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines to fly from Missouri to Italy one-way?

Can I find deals for flights from Missouri to Italy that include hotel bookings?

How can I find direct flights from Missouri to Italy?

Can I find deals for business class flights from Missouri to Italy?

What is the cheapest month to book a flight from Missouri to Italy?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Italy

See prices for flight routes from nearby airports that may be better suited for you.

Top 8 airlines flying from Missouri to Italy

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Missouri to Italy
Explore the most affordable flight options available from Missouri to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.