Italy

$241+ Cheap flights from Missouri to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — NAP
nov. 16 — nov. 231
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Find flight deals from Missouri to Italy

Cheapest flights from Missouri to Italy
Explore the most affordable flight options available from Missouri to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 17, 2025.

This Air Canada deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/186:43 pmSTL - MXP
2 stops32h 12mAir Canada
mié. 11/266:05 amMXP - STL
2 stops40h 24mAir Canada
Deal found 10/15$496
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/1810:00 amSTL - MXP
1 stop20h 05mUnited Airlines
mié. 11/263:05 pmMXP - STL
1 stop13h 35mUnited Airlines
Deal found 10/15$498
This Air Canada deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/34:05 pmSTL - MXP
2 stops15h 15mAir Canada
dom. 12/71:05 pmMXP - STL
2 stops32h 18mAir Canada
Deal found 10/14$502
This Travelocity deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/256:43 pmSTL - LIN
2 stops17h 07mMultiple Airlines
mar. 12/22:50 pmLIN - STL
2 stops31h 39mMultiple Airlines
Deal found 10/16$505
This Expedia deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/236:43 pmSTL - LIN
2 stops17h 07mMultiple Airlines
lun. 12/17:35 pmLIN - STL
2 stops50h 54mMultiple Airlines
Deal found 10/15$516
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/1811:35 amSTL - FCO
2 stops18h 05mLufthansa
mar. 11/256:45 pmFCO - STL
1 stop26h 10mLufthansa
Deal found 10/16$518
This Expedia deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/256:43 pmSTL - LIN
2 stops17h 07mLufthansa
mar. 12/26:55 pmLIN - STL
1 stop26h 00mLufthansa
Deal found 10/16$518
This Mytrip deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/174:05 pmSTL - FCO
1 stop12h 00mMultiple Airlines
mié. 11/267:05 amFCO - STL
1 stop13h 50mMultiple Airlines
Deal found 10/16$525
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/148:25 amSTL - FCO
1 stop17h 05mUnited Airlines
mié. 11/191:15 pmFCO - STL
2 stops32h 09mUnited Airlines
Deal found 10/16$532
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/28:00 amMCI - FCO
1 stop16h 45mUnited Airlines
vie. 12/121:10 pmFCO - MCI
2 stops35h 19mUnited Airlines
Deal found 10/15$532
This Air Canada deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/24:05 pmSTL - FCO
1 stop11h 50mAir Canada
vie. 12/121:10 pmFCO - STL
2 stops33h 30mAir Canada
Deal found 10/16$534
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/1111:36 amMCI - MXP
1 stop18h 29mUnited Airlines
mar. 11/181:05 pmMXP - MCI
2 stops39h 45mUnited Airlines
Deal found 10/14$537

Cheap flight deals from Missouri to Italy

Keep the following information in mind while searching for Missouri to Italy flight deals. Data was last updated octubre 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$471
(Gotogate)

One-way from

$241
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$906
Provider with most accurate pricing for Lambert-St Louis-Rome (ROM) flight deals.
Provider most trusted by Cheapflights users for Lambert-St Louis-Rome (ROM) flights.
From Missouri to Italy
One-way flight from Missouri to Italy
Highest demand for flights based on searches. 25% potential increase in price ($358 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($52 potential savings vs. average RT price).
Average for round-trip flights in October 2025

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 17, 2025.
Use the filters below to find and compare flights from Missouri to Italy that are best for you.

Fly from

Missouri

Fly to

Italy

Route

Depart

Return

Price

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

mar. 11/18

6:43 pm-9:55 am

2 stops32h 12m

Milan Malpensa

mié. 11/26

6:05 am-3:29 pm

2 stops40h 24m

$496

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

mar. 11/18

6:43 pm-9:55 am

2 stops32h 12m

Milan Malpensa

mié. 11/26

3:05 pm-9:40 pm

1 stop13h 35m

$498

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

mié. 12/3

4:05 pm-2:20 pm

2 stops15h 15m

Milan Malpensa

dom. 12/7

1:05 pm-2:23 pm

2 stops32h 18m

$502

St. LouisMilan

STL - LIN

STLLIN

Lambert-St Louis

lun. 2/9

4:05 pm-2:05 pm

2 stops15h 00m

Milan Linate

mar. 2/17

2:50 pm-3:29 pm

2 stops31h 39m

$503

St. LouisMilan

STL - LIN

STLLIN

Lambert-St Louis

mar. 11/25

6:43 pm-6:50 pm

2 stops17h 07m

Milan Linate

mar. 12/2

2:50 pm-3:29 pm

2 stops31h 39m

$505

St. LouisMilan

STL - LIN

STLLIN

Lambert-St Louis

mar. 3/10

8:20 am-11:55 am

2 stops21h 35m

Milan Linate

mar. 3/17

2:50 pm-3:29 pm

2 stops30h 39m

$507

St. LouisMilan

STL - LIN

STLLIN

Lambert-St Louis

mié. 3/11

8:00 am-11:55 am

2 stops21h 55m

Milan Linate

mié. 3/18

2:55 pm-3:29 pm

2 stops30h 34m

$507

St. LouisMilan

STL - LIN

STLLIN

Lambert-St Louis

lun. 2/9

11:20 am-11:55 am

2 stops17h 35m

Milan Linate

jue. 2/19

2:50 pm-3:29 pm

2 stops31h 39m

$507

St. LouisMilan

STL - LIN

STLLIN

Lambert-St Louis

mié. 3/11

8:25 am-11:55 am

2 stops21h 30m

Milan Linate

mar. 3/17

2:50 pm-3:29 pm

2 stops30h 39m

$507

St. LouisMilan

STL - LIN

STLLIN

Lambert-St Louis

dom. 2/8

12:00 pm-11:15 am

2 stops16h 15m

Milan Linate

vie. 2/20

6:30 am-8:39 pm

2 stops21h 09m

$510

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/15

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Italy

What is the cheapest month to book a flight from Missouri to Italy?

Currently, June is the cheapest month in which you can book a flight from Missouri to Italy (average of $450). Flying from Missouri to Italy in July is currently the most expensive (average of $863). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to IT?

Find hourly flight availability from Missouri to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 17, 2025.

It’s typically best to fly out from Missouri to Italy in the evening. Doing so could potentially save you 16% on the flight price compared to flying in the morning, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Missouri to Italy?

    For as low as $544, Air Canada can have you in Italy from Missouri in 22h 48m. Airlines will cover a distance of 5320 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Italy one-way?

    $298 is the cheapest one-way deal found within the past few days, from Air Canada. You may also be able to find cheap deals on Lufthansa and United Airlines, with prices starting from $298 and $322, respectively.

  • Can I find deals for flights from Missouri to Italy that include hotel bookings?

    Yes. In addition to deals on Missouri to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Italy.

  • Can I find deals for business class flights from Missouri to Italy?

    Yes. Cheapflights offers flight deals from Missouri to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Italy?

    Currently, June is the cheapest month in which you can book a flight from Missouri to Italy (average of $450). Flying from Missouri to Italy in July is currently the most expensive (average of $863). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Italy

See prices for flight routes from nearby airports that may be better suited for you.

Top 9 airlines flying from Missouri to Italy

Discover the top 9 airlines that operate flights from Missouri to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$485Average$1,155FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$493Average$1,302FlexibilityNo cancel feeOn-time76%
IberiaCheapest$536Average$1,215FlexibilityNo cancel feeOn-time77%
DeltaCheapest$554Average$1,092FlexibilityNo cancel feeOn-timeN/A
British AirwaysCheapest$560Average$1,093FlexibilityNo cancel feeOn-time70%
KLMCheapest$573Average$992FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$619Average$1,192FlexibilityNo cancel feeOn-time71%
Air FranceCheapest$655Average$1,282FlexibilityNo cancel feeOn-time77%
Air CanadaCheapest$705Average$1,209FlexibilityNo cancel feeOn-time67%

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