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Italy

$298+ Cheap flights from Missouri to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — NAP
Apr 8 — Apr 151
Wed 4/8
Wed 4/15
1 adult, Economy
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Cheap flight deals from Missouri to Italy

Cheapest flights from Missouri to Italy
Explore the most affordable flight options available from Missouri to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 9, 2026.

This Finnair deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:45 pm
MCI
-
MXP
2 stops21h 30m
Finnair
Fri 11/207:00 pm
MXP
-
MCI
2 stops31h 18m
Finnair
Deal found 3/5$523
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:15 pm
MCI
-
LIN
2 stops14h 00m
Delta
Fri 11/206:30 am
LIN
-
MCI
2 stops21h 48m
Delta
Deal found 3/4$524
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:51 am
STL
-
LIN
2 stops13h 59m
Delta
Wed 8/266:40 am
LIN
-
STL
2 stops20h 51m
Delta
Deal found 3/4$524
This Air France deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1212:04 pm
MCI
-
MXP
2 stops15h 21m
Air France
Wed 8/266:45 am
MXP
-
MCI
2 stops17h 28m
Air France
Deal found 3/4$527
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:00 am
MCI
-
MXP
1 stop20h 05m
United Airlines
Fri 11/209:10 am
MXP
-
MCI
2 stops19h 57m
United Airlines
Deal found 3/4$540
This KLM deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1212:04 pm
MCI
-
MXP
2 stops15h 21m
Multiple Airlines
Wed 8/2611:40 am
MXP
-
MCI
1 stop19h 12m
Multiple Airlines
Deal found 3/4$541
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:00 am
STL
-
MXP
2 stops22h 20m
United Airlines
Wed 8/2612:20 pm
MXP
-
STL
2 stops31h 29m
United Airlines
Deal found 3/5$545
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
MCI
-
MXP
2 stops21h 20m
United Airlines
Wed 8/2612:20 pm
MXP
-
MCI
2 stops34h 32m
United Airlines
Deal found 3/5$545
This BusinessClass deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:11 pm
MCI
-
MXP
1 stop33h 54m
British Airways
Wed 8/262:20 pm
MXP
-
MCI
1 stop14h 35m
British Airways
Deal found 3/4$548
This FlightHub deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am
MCI
-
MXP
2 stops20h 55m
Air Canada
Fri 11/201:05 pm
MXP
-
MCI
3 stops36h 37m
Air Canada
Deal found 3/4$550
This BusinessClass deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/129:35 pm
STL
-
MXP
1 stop19h 00m
British Airways
Wed 8/268:25 am
MXP
-
STL
2 stops18h 54m
British Airways
Deal found 3/4$555
This Air Canada deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/412:10 pm
STL
-
MXP
1 stop15h 10m
Air Canada
Wed 8/1912:20 pm
MXP
-
STL
2 stops32h 42m
Air Canada
Deal found 3/5$559

Find flight deals from Missouri to Italy

Keep the following information in mind while searching for Missouri to Italy flight deals. Data was last updated March 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$524
(Delta)

One-way from

$275
(Booking.com)

Popular in

June

Cheapest in

February

Average price

$894
Provider with most accurate pricing for Lambert-St Louis-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Rome (ROM) flights.
Search Deals
From Missouri to Italy
Search Deals
One-way flight from Missouri to Italy
Search Deals
Highest demand for flights based on searches. 30% potential increase in price ($399 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($62 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 9, 2026.
Use the filters below to find and compare flights from Missouri to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Kansas CityMilan

MCI - MXP

MCIMXP

Kansas City

Wed 8/12

6:20 pm-10:20 am

2 stops33h 00m

Milan Malpensa

Wed 8/19

12:20 pm-4:19 pm

2 stops34h 59m

$545

Kansas CityMilan

MCI - MXP

MCIMXP

Kansas City

Thu 4/16

6:15 am-10:20 am

2 stops21h 05m

Milan Malpensa

Thu 4/23

12:20 pm-7:45 pm

2 stops38h 25m

$545

Kansas CityMilan

MCI - MXP

MCIMXP

Kansas City

Mon 4/6

7:00 pm-1:20 pm

1 stop11h 20m

Milan Malpensa

Sun 4/19

9:00 am-10:30 pm

2 stops20h 30m

$620

St. LouisMilan

STL - LIN

STLLIN

Lambert-St Louis

Mon 8/3

10:45 am-11:20 am

2 stops17h 35m

Milan Linate

Thu 8/13

1:00 pm-11:37 pm

2 stops17h 37m

$680

St. LouisVenice

STL - VCE

STLVCE

Lambert-St Louis

Mon 8/17

8:44 am-7:55 am

1 stop16h 11m

Venice Marco Polo

Fri 8/21

12:20 pm-8:02 pm

1 stop14h 42m

$680

Kansas CityMilan

MCI - MXP

MCIMXP

Kansas City

Wed 8/12

6:23 am-10:20 am

2 stops20h 57m

Milan Malpensa

Wed 8/26

3:20 pm-12:48 am

1 stop16h 28m

$684

St. LouisVenice

STL - VCE

STLVCE

Lambert-St Louis

Tue 8/4

10:20 am-7:55 am

2 stops14h 35m

Venice Marco Polo

Wed 8/19

6:30 am-8:02 pm

2 stops20h 32m

$690

St. LouisFlorence

STL - FLR

STLFLR

Lambert-St Louis

Fri 4/17

7:05 am-10:20 pm

2 stops32h 15m

Florence Peretola

Wed 4/22

7:05 am-7:30 pm

1 stop19h 25m

$694

St. LouisMilan

STL - MXP

STLMXP

Lambert-St Louis

Mon 8/3

11:51 am-12:05 pm

2 stops17h 14m

Milan Malpensa

Thu 8/13

6:45 am-4:55 pm

2 stops17h 10m

$712

Kansas CityVenice

MCI - VCE

MCIVCE

Kansas City

Tue 3/24

6:41 pm-5:20 pm

2 stops16h 39m

Venice Marco Polo

Tue 3/31

11:05 am-7:56 pm

1 stop15h 51m

$741

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/8

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Italy

What is the cheapest month to book a flight from Missouri to Italy?

Currently, March is the cheapest month in which you can book a flight from Missouri to Italy (average of $441). Flying from Missouri to Italy in July is currently the most expensive (average of $790). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Italy?

    For as low as $559, United Airlines can have you in Italy from Missouri in 15h 10m. Airlines will cover a distance of 4752 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Italy one-way?

    $42 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on Delta and Southwest, with prices starting from $98 and $108, respectively.

  • Can I find deals for flights from Missouri to Italy that include hotel bookings?

    Yes. In addition to deals on Missouri to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Italy.

  • Can I find deals for business class flights from Missouri to Italy?

    Yes. Cheapflights offers flight deals from Missouri to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Italy?

    Currently, March is the cheapest month in which you can book a flight from Missouri to Italy (average of $441). Flying from Missouri to Italy in July is currently the most expensive (average of $790). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 9 airlines flying from Missouri to Italy

Discover the top 9 airlines that operate flights from Missouri to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$472Average$934FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$485Average$1,030FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$490Average$1,114FlexibilityNo cancel feeOn-time76%
DeltaCheapest$498Average$1,066FlexibilityNo cancel feeOn-timeN/A
KLMCheapest$506Average$906FlexibilityNo cancel feeOn-time75%
Air CanadaCheapest$552Average$1,009FlexibilityNo cancel feeOn-time67%
American AirlinesCheapest$559Average$1,110FlexibilityNo cancel feeOn-time71%
Air FranceCheapest$655Average$1,282FlexibilityNo cancel feeOn-time77%
IberiaCheapest$692Average$1,323FlexibilityNo cancel feeOn-time77%

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