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$424+ Cheap flights from Santa Fe (SAF) to Iowa

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/14. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — DSM
Jan 15 — Jan 221
Thu 1/15
Thu 1/22
1 adult, Economy
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Cheap flight deals from Santa Fe to Iowa

Cheapest flights from Santa Fe to Iowa
Explore the most affordable flight options available from Santa Fe to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/231:22 pmSAF - DSM
1 stop6h 08mUnited Airlines
Sun 12/281:30 pmDSM - SAF
1 stop4h 32mUnited Airlines
Deal found 12/15$904

Find flight deals from Santa Fe to Iowa

Keep the following information in mind while searching for Santa Fe to Iowa flight deals. Data was last updated December 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$424
(United Airlines)
Provider with most accurate pricing for Santa Fe-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santa Fe-Des Moines flights.
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From Santa Fe to Iowa
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Fe to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Santa Fe to Iowa that are best for you.

Fly from

Santa Fe

Fly to

Iowa

Route

Depart

Return

Price

Santa FeCedar Rapids

SAF - CID

SAFCID

Santa Fe

Wed 1/14

6:05 pm-2:11 pm

1 stop19h 06m

Cedar Rapids

Sat 1/17

8:50 am-2:54 pm

1 stop7h 04m

$424

Santa FeDes Moines

SAF - DSM

SAFDSM

Santa Fe

Sat 2/14

3:20 pm-8:41 pm

1 stop4h 21m

Des Moines

Wed 2/18

9:04 am-9:24 am

1 stop25h 20m

$495

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Best time to book a flight from Santa Fe to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Fe to Iowa

What is the cheapest month to book a flight from Santa Fe to Iowa?

Currently, May is the cheapest month in which you can book a flight from Santa Fe to Iowa (average of $211). Flying from Santa Fe to Iowa in February is currently the most expensive (average of $397). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santa Fe to Iowa?

    Santa Fe (SAF) is the airport you will fly out of if you book a flight from Santa Fe to Iowa. It is only a 9.8 mi journey to Santa Fe (SAF) from Santa Fe’s city center.

  • How long is the flight from Santa Fe to Iowa?

    Departing from Santa Fe to Iowa will take you 19h 06m. There are 885 mi between Santa Fe and Iowa.

  • Can I find deals for flights from Santa Fe to Iowa that include hotel bookings?

    Yes. In addition to deals on Santa Fe to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to Iowa.

  • Can I find deals for business class flights from Santa Fe to Iowa?

    Yes. Cheapflights offers flight deals from Santa Fe to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Fe to Iowa?

    Currently, May is the cheapest month in which you can book a flight from Santa Fe to Iowa (average of $211). Flying from Santa Fe to Iowa in February is currently the most expensive (average of $397). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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