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$146+ Cheap flights from Louisville (SDF) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — DSM
Apr 12 — Apr 191
Sun 4/12
Sun 4/19
1 adult, Economy
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Cheap flight deals from Louisville to Iowa

Cheapest flights from Louisville to Iowa
Explore the most affordable flight options available from Louisville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.

This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
SDF
-
MLI
1 stop5h 20m
Delta
Wed 6/175:55 am
MLI
-
SDF
1 stop4h 41m
Delta
Deal found 3/9$269
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:00 am
SDF
-
CID
1 stop4h 18m
American Airlines
Sun 5/36:00 am
CID
-
SDF
1 stop5h 16m
American Airlines
Deal found 3/9$269
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:15 am
SDF
-
OMA
1 stop6h 04m
United Airlines
Sat 5/93:17 pm
OMA
-
SDF
1 stop6h 13m
United Airlines
Deal found 3/11$277
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:00 am
SDF
-
DSM
1 stop6h 30m
American Airlines
Sat 5/235:00 am
DSM
-
SDF
1 stop4h 17m
American Airlines
Deal found 3/10$281
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:40 am
SDF
-
OMA
1 stop3h 55m
Southwest
Sat 5/91:20 pm
OMA
-
SDF
2 stops6h 30m
Southwest
Deal found 3/11$282
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:35 pm
SDF
-
MLI
1 stop5h 55m
Delta
Thu 4/165:11 pm
MLI
-
SDF
1 stop5h 48m
Delta
Deal found 3/12$289
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:00 am
SDF
-
DSM
1 stop7h 07m
American Airlines
Sat 4/41:37 pm
DSM
-
SDF
1 stop6h 49m
American Airlines
Deal found 3/12$291
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/99:43 am
SDF
-
MLI
2 stops9h 24m
American Airlines
Thu 4/165:15 am
MLI
-
SDF
1 stop4h 31m
American Airlines
Deal found 3/12$294
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/99:43 am
SDF
-
OMA
1 stop5h 00m
American Airlines
Mon 5/115:07 pm
OMA
-
SDF
1 stop6h 18m
American Airlines
Deal found 3/13$299
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:45 pm
SDF
-
CID
1 stop6h 00m
United Airlines
Sat 3/281:10 pm
CID
-
SDF
1 stop6h 04m
United Airlines
Deal found 3/9$299
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/274:25 pm
SDF
-
CID
1 stop7h 27m
Delta
Tue 3/316:45 am
CID
-
SDF
2 stops5h 52m
Delta
Deal found 3/12$304
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:15 am
SDF
-
CID
1 stop5h 56m
Delta
Sat 4/46:45 am
CID
-
SDF
1 stop4h 06m
Delta
Deal found 3/12$309

Find flight deals from Louisville to Iowa

Keep the following information in mind while searching for Louisville to Iowa flight deals. Data was last updated March 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$269
(Delta)

One-way from

$146
(Delta)
Provider with most accurate pricing for Louisville Intl-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Louisville Intl-Des Moines flights.
Search Deals
From Louisville Intl to Iowa
Search Deals
One-way flight from Louisville Intl to Iowa
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Louisville to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleMoline

SDF - MLI

SDFMLI

Louisville Intl

Wed 6/3

6:00 am-10:20 am

1 stop5h 20m

Moline Quad-City

Wed 6/17

5:55 am-11:36 am

1 stop4h 41m

$269

LouisvilleCedar Rapids

SDF - CID

SDFCID

Louisville Intl

Thu 4/30

9:00 am-12:18 pm

1 stop4h 18m

Cedar Rapids

Sun 5/3

6:00 am-12:16 pm

1 stop5h 16m

$269

LouisvilleOmaha

SDF - OMA

SDFOMA

Louisville Intl

Sat 5/2

7:15 am-12:19 pm

1 stop6h 04m

Omaha Eppley Airfield

Sat 5/9

3:17 pm-10:30 pm

1 stop6h 13m

$277

LouisvilleMoline

SDF - MLI

SDFMLI

Louisville Intl

Thu 4/9

5:35 pm-10:30 pm

1 stop5h 55m

Moline Quad-City

Thu 4/16

5:11 pm-11:59 pm

1 stop5h 48m

$289

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Thu 4/9

7:05 am-10:48 am

1 stop4h 43m

Des Moines

Mon 4/13

6:31 pm-11:59 pm

1 stop4h 28m

$291

LouisvilleMoline

SDF - MLI

SDFMLI

Louisville Intl

Thu 4/9

9:43 am-6:07 pm

2 stops9h 24m

Moline Quad-City

Thu 4/16

5:15 am-10:46 am

1 stop4h 31m

$294

LouisvilleCedar Rapids

SDF - CID

SDFCID

Louisville Intl

Thu 4/2

6:15 am-11:11 am

1 stop5h 56m

Cedar Rapids

Sat 4/4

6:45 am-11:51 am

1 stop4h 06m

$309

LouisvilleOmaha

SDF - OMA

SDFOMA

Louisville Intl

Thu 5/14

7:33 am-2:00 pm

1 stop7h 27m

Omaha Eppley Airfield

Sat 5/16

2:55 pm-11:11 pm

1 stop7h 16m

$319

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Wed 5/20

1:35 pm-9:15 pm

2 stops8h 40m

Des Moines

Sat 5/23

5:35 am-10:05 am

1 stop3h 30m

$321

LouisvilleOmaha

SDF - OMA

SDFOMA

Louisville Intl

Tue 5/26

7:15 pm-10:20 pm

1 stop4h 05m

Omaha Eppley Airfield

Sun 5/31

4:35 pm-9:50 pm

1 stop4h 15m

$335

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/9

Showing 1-10 of 45 resultsSorted by cheapest first
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Best time to book a flight from Louisville to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Iowa

What is the cheapest month to book a flight from Louisville to Iowa?

Currently, July is the cheapest month in which you can book a flight from Louisville to Iowa (average of $228). Flying from Louisville to Iowa in August is currently the most expensive (average of $261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated March 13, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Louisville to Iowa. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,291 reviews

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,291 reviews
Delta
7.9
Good
8,291 reviews

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,423 reviews
Delta
7.9
Good
8,291 reviews

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,464 reviews
Delta
7.9
Good
8,291 reviews

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Louisville to Iowa?

    Louisville Intl (SDF) is the airport you will fly out of if you book a flight from Louisville to Iowa. It is only a 5.3 mi journey to Louisville Intl (SDF) from Louisville’s city center.

  • How long is the flight from Louisville to Iowa?

    For as low as $269, Delta can have you in Iowa from Louisville in 4h 18m. Louisville and Iowa are separated by a distance of 407 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Louisville to Iowa?

    When deciding which route to take from Louisville to Iowa consider Louisville Intl - Des Moines, Louisville Intl - Omaha Eppley Airfield or Louisville Intl - Cedar Rapids as they are the most popular.

  • Can I find deals for flights from Louisville to Iowa that include hotel bookings?

    Yes. In addition to deals on Louisville to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Iowa.

  • Can I find deals for business class flights from Louisville to Iowa?

    Yes. Cheapflights offers flight deals from Louisville to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Iowa?

    Currently, July is the cheapest month in which you can book a flight from Louisville to Iowa (average of $228). Flying from Louisville to Iowa in August is currently the most expensive (average of $261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Louisville to Iowa

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Top 3 airlines flying from Louisville to Iowa

Discover the top 3 airlines that operate flights from Louisville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$105Average$282FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$158Average$257FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$470FlexibilityNo cancel feeOn-time69%

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