$148+ Cheap flights from Knoxville (TYS) to Iowa
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — DSM
Jun 5 — Jun 121
Round-trip
1 adult, Economy
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Cheapest flights from Knoxville to IowaExplore the most affordable flight options available from Knoxville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 6, 2026.
Explore the most affordable flight options available from Knoxville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/23:38 pm
TYS
- DSM
1 stop8h 09m
Allegiant Air
Fri 8/73:27 pm
DSM
- TYS
1 stop7h 04m
Allegiant Air
Deal found 5/1![Allegiant Air logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/73:46 pm
TYS
- DSM
1 stop8h 06m
Allegiant Air
Thu 6/115:02 pm
DSM
- TYS
1 stop27h 48m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$229
This Frontier deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:19 pm
TYS
- OMA
1 stop24h 15m
Frontier
Sun 6/78:19 pm
OMA
- TYS
1 stop22h 14m
Frontier
Deal found 5/4![Frontier logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1910:30 am
TYS
- OMA
1 stop28h 21m
Multiple Airlines
Sat 5/238:19 pm
OMA
- TYS
1 stop16h 40m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/73:46 pm
TYS
- DSM
1 stop8h 06m
Allegiant Air
Tue 6/94:11 pm
DSM
- TYS
1 stop25h 10m
Allegiant Air
Deal found 5/2![Allegiant Air logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/73:46 pm
TYS
- DSM
1 stop8h 06m
Allegiant Air
Sun 6/1410:53 am
DSM
- TYS
1 stop24h 06m
Allegiant Air
Deal found 5/2![Allegiant Air logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/11:36 pm
TYS
- DSM
1 stop10h 48m
Allegiant Air
Thu 6/45:02 pm
DSM
- TYS
1 stop27h 48m
Allegiant Air
Deal found 5/2![Allegiant Air logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:01 pm
TYS
- OMA
1 stop29h 05m
Allegiant Air
Fri 6/59:06 pm
OMA
- TYS
1 stop23h 32m
Allegiant Air
Deal found 5/1![Allegiant Air logo]()
$288
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:35 am
TYS
- OMA
1 stop4h 45m
Delta
Mon 6/85:52 pm
OMA
- TYS
1 stop4h 09m
Delta
Deal found 5/4![Delta logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/73:46 pm
TYS
- DSM
1 stop8h 06m
Multiple Airlines
Sun 6/145:02 pm
DSM
- TYS
2 stops27h 48m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$306
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:59 pm
TYS
- MLI
1 stop5h 22m
Delta
Tue 6/25:17 pm
MLI
- TYS
1 stop5h 44m
Delta
Deal found 5/1![Delta logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/73:46 pm
TYS
- DSM
1 stop8h 06m
Multiple Airlines
Thu 6/113:37 pm
DSM
- TYS
2 stops30h 57m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$312
Best flights from Knoxville to IowaDiscover carefully curated flight deals from Knoxville to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 6, 2026.
Discover carefully curated flight deals from Knoxville to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1910:30 am
TYS
- OMA
1 stop28h 21m
Multiple Airlines
Sat 5/238:19 pm
OMA
- TYS
1 stop16h 40m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$255
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:35 am
TYS
- OMA
1 stop4h 45m
Delta
Mon 6/85:52 pm
OMA
- TYS
1 stop4h 09m
Delta
Deal found 5/4![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:35 am
TYS
- OMA
2 stops7h 20m
Southwest
Tue 6/25:30 am
OMA
- TYS
2 stops10h 40m
Southwest
Deal found 4/30![Southwest logo]()
$346
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:48 pm
TYS
- MLI
1 stop4h 06m
American Airlines
Sun 5/1712:49 pm
MLI
- TYS
1 stop6h 29m
American Airlines
Deal found 5/2![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:30 am
TYS
- OMA
1 stop6h 48m
United Airlines
Wed 8/193:13 pm
OMA
- TYS
1 stop4h 35m
United Airlines
Deal found 5/2![United Airlines logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:56 am
TYS
- DSM
1 stop28h 19m
Allegiant Air
Mon 5/182:03 pm
DSM
- TYS
1 stop23h 55m
Allegiant Air
Deal found 5/2![Allegiant Air logo]()
$403
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:40 am
TYS
- MLI
1 stop5h 40m
Delta
Tue 6/25:17 pm
MLI
- TYS
1 stop5h 44m
Delta
Deal found 5/3![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:40 am
TYS
- OMA
1 stop5h 29m
Delta
Tue 6/25:30 am
OMA
- TYS
1 stop4h 39m
Delta
Deal found 4/30![Delta logo]()
$326
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/23:38 pm
TYS
- DSM
1 stop8h 09m
Multiple Airlines
Fri 8/77:05 pm
DSM
- TYS
2 stops20h 09m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$365
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:35 am
TYS
- OMA
2 stops7h 20m
Southwest
Fri 6/54:15 pm
OMA
- TYS
1 stop3h 55m
Southwest
Deal found 5/1![Southwest logo]()
$372
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:30 am
TYS
- OMA
1 stop5h 25m
Delta
Mon 9/286:30 pm
OMA
- TYS
1 stop4h 17m
Delta
Deal found 5/4![Delta logo]()
$326
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:07 pm
TYS
- MLI
2 stops7h 07m
American Airlines
Tue 6/96:00 am
MLI
- TYS
2 stops8h 15m
American Airlines
Deal found 5/3![American Airlines logo]()
$397
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/198:00 am
TYS
- DSM
1 stop15h 37m
Allegiant Air
Sun 6/216:00 am
DSM
- TYS
2 stops15h 16m
Allegiant Air
Deal found 5/4![Allegiant Air logo]()
$407
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/287:05 am
TYS
- OMA
1 stop3h 45m
Southwest
Tue 6/3010:35 am
OMA
- TYS
2 stops8h 45m
Southwest
Deal found 5/1![Southwest logo]()
$372
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:00 am
TYS
- MLI
1 stop4h 04m
United Airlines
Sat 5/232:31 pm
MLI
- TYS
1 stop5h 25m
United Airlines
Deal found 5/4![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:00 am
TYS
- MLI
1 stop4h 04m
United Airlines
Sun 5/246:30 am
MLI
- TYS
1 stop5h 48m
United Airlines
Deal found 5/5![United Airlines logo]()
$419
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/27:00 pm
TYS
- DSM
2 stops5h 45m
Southwest
Fri 8/75:40 am
DSM
- TYS
2 stops11h 55m
Southwest
Deal found 5/1![Southwest logo]()
$393
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:00 am
TYS
- DSM
2 stops6h 31m
American Airlines
Wed 5/2012:00 pm
DSM
- TYS
1 stop7h 18m
American Airlines
Deal found 5/1![American Airlines logo]()
$442
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:46 pm
TYS
- OMA
1 stop5h 04m
Delta
Tue 6/3010:23 am
OMA
- TYS
1 stop6h 39m
Delta
Deal found 5/4![Delta logo]()
$367
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:43 pm
TYS
- DSM
1 stop6h 52m
American Airlines
Sun 6/216:55 am
DSM
- TYS
1 stop7h 20m
American Airlines
Deal found 5/5![American Airlines logo]()
$447
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:45 pm
TYS
- OMA
2 stops5h 15m
Southwest
Wed 6/245:20 am
OMA
- TYS
2 stops10h 40m
Southwest
Deal found 5/5![Southwest logo]()
$407
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/83:30 pm
TYS
- DSM
1 stop8h 15m
United Airlines
Sat 5/96:15 am
DSM
- TYS
1 stop6h 01m
United Airlines
Deal found 5/4![United Airlines logo]()
$486
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/112:15 pm
TYS
- DSM
2 stops11h 50m
Southwest
Fri 6/56:10 am
DSM
- TYS
2 stops14h 00m
Southwest
Deal found 5/3![Southwest logo]()
$449
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:10 am
TYS
- LSE
1 stop5h 12m
American Airlines
Sat 5/3011:44 am
LSE
- TYS
2 stops11h 12m
American Airlines
Deal found 5/4![American Airlines logo]()
$500
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:00 am
TYS
- DSM
1 stop5h 30m
United Airlines
Sun 6/76:00 am
DSM
- TYS
1 stop6h 18m
United Airlines
Deal found 5/1![United Airlines logo]()
$509
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:50 pm
TYS
- DSM
2 stops10h 20m
Southwest
Mon 6/15:25 am
DSM
- TYS
2 stops11h 45m
Southwest
Deal found 5/2![Southwest logo]()
$452
Last-minute flights from Knoxville to IowaDiscover last-minute flight deals from Knoxville to Iowa. Data last updated May 6, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Iowa. Data last updated May 6, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1910:30 am
TYS
- OMA
1 stop28h 21m
Multiple Airlines
Sat 5/238:19 pm
OMA
- TYS
1 stop16h 40m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$255
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:59 pm
TYS
- MLI
1 stop5h 22m
Delta
Tue 6/25:17 pm
MLI
- TYS
1 stop5h 44m
Delta
Deal found 5/1![Delta logo]()
$309
This Frontier deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:19 pm
TYS
- OMA
1 stop24h 15m
Frontier
Sun 6/78:19 pm
OMA
- TYS
1 stop22h 14m
Frontier
Deal found 5/4![Frontier logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:01 pm
TYS
- OMA
1 stop29h 05m
Allegiant Air
Fri 6/59:06 pm
OMA
- TYS
1 stop23h 32m
Allegiant Air
Deal found 5/1![Allegiant Air logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/11:36 pm
TYS
- DSM
1 stop10h 48m
Allegiant Air
Thu 6/45:02 pm
DSM
- TYS
1 stop27h 48m
Allegiant Air
Deal found 5/2![Allegiant Air logo]()
$281
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:35 am
TYS
- OMA
1 stop4h 45m
Delta
Mon 6/85:52 pm
OMA
- TYS
1 stop4h 09m
Delta
Deal found 5/4![Delta logo]()
$303
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:07 pm
TYS
- MLI
2 stops7h 07m
American Airlines
Tue 6/94:24 pm
MLI
- TYS
1 stop6h 23m
American Airlines
Deal found 5/4![American Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/73:46 pm
TYS
- DSM
1 stop8h 06m
Allegiant Air
Thu 6/115:02 pm
DSM
- TYS
1 stop27h 48m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/73:46 pm
TYS
- DSM
1 stop8h 06m
Allegiant Air
Tue 6/94:11 pm
DSM
- TYS
1 stop25h 10m
Allegiant Air
Deal found 5/2![Allegiant Air logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/73:46 pm
TYS
- DSM
1 stop8h 06m
Allegiant Air
Sun 6/1410:53 am
DSM
- TYS
1 stop24h 06m
Allegiant Air
Deal found 5/2![Allegiant Air logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/73:46 pm
TYS
- DSM
1 stop8h 06m
Multiple Airlines
Sun 6/145:02 pm
DSM
- TYS
2 stops27h 48m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/73:46 pm
TYS
- DSM
1 stop8h 06m
Multiple Airlines
Thu 6/113:37 pm
DSM
- TYS
2 stops30h 57m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$312
One-way flights from Knoxville to IowaSearch for one-way flight options from Knoxville to Iowa. Find affordable one-way fares based on user searches. Data last updated May 6, 2026.
Search for one-way flight options from Knoxville to Iowa. Find affordable one-way fares based on user searches. Data last updated May 6, 2026.
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:33 pm
TYS
- DSM
1 stop7h 24m
American Airlines
Deal found 5/4![American Airlines logo]()
$148
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:30 am
TYS
- OMA
1 stop4h 47m
United Airlines
Deal found 5/3![United Airlines logo]()
$148
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1612:45 pm
TYS
- OMA
2 stops10h 45m
Southwest
Deal found 5/3![Southwest logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:23 pm
TYS
- OMA
1 stop17h 35m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/123:51 pm
TYS
- OMA
1 stop26h 15m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$173
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/267:35 am
TYS
- DSM
1 stop6h 59m
Delta
Deal found 5/5![Delta logo]()
$179
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/138:05 pm
TYS
- OMA
1 stop5h 15m
American Airlines
Deal found 5/5![American Airlines logo]()
$179
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:50 pm
TYS
- DSM
2 stops10h 20m
Southwest
Deal found 5/4![Southwest logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/144:31 pm
TYS
- OMA
1 stop18h 00m
Allegiant Air
Deal found 5/1![Allegiant Air logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:00 am
TYS
- MLI
1 stop8h 34m
Allegiant Air
Deal found 5/4![Allegiant Air logo]()
$210
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:54 pm
TYS
- OMA
1 stop5h 38m
American Airlines
Deal found 5/1![American Airlines logo]()
$219
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/610:00 am
TYS
- OMA
2 stops12h 56m
United Airlines
Deal found 5/3![United Airlines logo]()
$224
Find flight deals from Knoxville to Iowa
Keep the following information in mind while searching for Knoxville to Iowa flight deals. Data was last updated May 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $224 (Kiwi.com) |
One-way from | $148 (American Airlines) |
Popular in | March |
Cheapest in | February |
Average price | $368 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
Use the filters below to find and compare flights from Knoxville to Iowa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleOmaha
TYS - OMA
TYSOMA
Knoxville McGhee Tyson
Tue 5/19
10:30 am-1:51 pm
1 stop28h 21m
Omaha Eppley Airfield
Sat 5/23
8:19 pm-1:59 pm
1 stop16h 40m
$255
Quickest round-trip
KnoxvilleOmaha
TYS - OMA
TYSOMA
Knoxville McGhee Tyson
Tue 6/2
8:35 am-12:20 pm
1 stop4h 45m
Omaha Eppley Airfield
Mon 6/8
5:52 pm-11:01 pm
1 stop4h 09m
$303
KnoxvilleMoline
TYS - MLI
TYSMLI
Knoxville McGhee Tyson
Tue 5/26
5:40 am-10:20 am
1 stop5h 40m
Moline Quad-City
Tue 6/2
5:17 pm-12:01 am
1 stop5h 44m
$309
KnoxvilleOmaha
TYS - OMA
TYSOMA
Knoxville McGhee Tyson
Fri 5/29
5:40 am-10:09 am
1 stop5h 29m
Omaha Eppley Airfield
Tue 6/2
5:30 am-11:09 am
1 stop4h 39m
$326
KnoxvilleOmaha
TYS - OMA
TYSOMA
Knoxville McGhee Tyson
Wed 9/23
5:30 am-9:55 am
1 stop5h 25m
Omaha Eppley Airfield
Mon 9/28
6:30 pm-11:47 pm
1 stop4h 17m
$326
KnoxvilleOmaha
TYS - OMA
TYSOMA
Knoxville McGhee Tyson
Fri 5/29
6:35 am-12:55 pm
2 stops7h 20m
Omaha Eppley Airfield
Tue 6/2
5:30 am-5:10 pm
2 stops10h 40m
$346
KnoxvilleDes Moines
TYS - DSM
TYSDSM
Knoxville McGhee Tyson
Sun 8/2
3:38 pm-10:47 pm
1 stop8h 09m
Des Moines
Fri 8/7
7:05 pm-4:14 pm
2 stops20h 09m
$365
KnoxvilleOmaha
TYS - OMA
TYSOMA
Knoxville McGhee Tyson
Fri 6/26
7:46 pm-11:50 pm
1 stop5h 04m
Omaha Eppley Airfield
Tue 6/30
10:23 am-6:02 pm
1 stop6h 39m
$367
KnoxvilleMoline
TYS - MLI
TYSMLI
Knoxville McGhee Tyson
Fri 5/15
8:48 pm-11:54 pm
1 stop4h 06m
Moline Quad-City
Sun 5/17
12:49 pm-8:18 pm
1 stop6h 29m
$369
KnoxvilleOmaha
TYS - OMA
TYSOMA
Knoxville McGhee Tyson
Fri 5/29
6:35 am-12:55 pm
2 stops7h 20m
Omaha Eppley Airfield
Fri 6/5
4:15 pm-9:10 pm
1 stop3h 55m
$372
Showing 1-10 of 43 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Iowa
Have a flexible travel schedule? Discover the best time to fly to Iowa from Knoxville with our price prediction graph.
TYS-DSM
TYS-OMA
TYS-MLI
TYS-LSE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Iowa
TYS-USIA
TYS-DSM
TYS-OMA
TYS-MLI
TYS-LSE
What is the cheapest month to book a flight from Knoxville to Iowa?
Currently, September is the cheapest month in which you can book a flight from Knoxville to Iowa (average of $197). Flying from Knoxville to Iowa in March is currently the most expensive (average of $428). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to Iowa?
Reviews of airlines servicing Iowa
Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated May 6, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Knoxville to Iowa to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Comfort
7.9
Overall
7.9
Crew
8.5
Food
7.2
Boarding
8.1
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Entertainment
7.8
Comfort
7.9
Overall
7.9
Crew
8.5
Food
7.2
Boarding
8.1
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Entertainment
7.8
Comfort
7.9
Overall
7.9
Crew
8.5
Food
7.2
Boarding
8.1
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Entertainment
7.8
Comfort
7.9
Overall
7.9
Crew
8.5
Food
7.2
Boarding
8.1
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Iowa
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Complete your trip
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Knoxville and Iowa flights
Browse other Knoxville and Iowa flight options. Last updated on May 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Knoxville to Iowa flights
Consider these flights traveling from Knoxville to Iowa.
Top 3 airlines flying from Knoxville to Iowa
Discover the top 3 airlines that operate flights from Knoxville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$223 | Average$343 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$226 | Average$385 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$332 | FlexibilityNo cancel fee | On-timeN/A |