$133+ Cheap flights from Knoxville (TYS) to Iowa
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/10. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — DSM
Nov 29 — Dec 61
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Iowa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Iowa
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to IowaExplore the most affordable flight options available from Knoxville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Knoxville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:50 am -
1 stop5h 08m
Mon 12/78:00 am -
1 stop6h 26m
Deal found 10/29![American Airlines logo]()
$263
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:05 pm -
1 stop7h 37m
Tue 11/176:05 am -
1 stop6h 08m
Deal found 10/26![United Airlines logo]()
$313
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:14 pm -
1 stop5h 12m
Tue 11/173:31 pm -
1 stop5h 08m
Deal found 10/26![American Airlines logo]()
$317
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:40 pm -
1 stop6h 16m
Thu 11/268:03 am -
1 stop4h 47m
Deal found 10/27![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:30 pm -
1 stop5h 36m
Thu 11/2611:00 am -
2 stops7h 23m
Deal found 10/27![Delta logo]()
$344
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/178:01 pm -
1 stop4h 57m
Sun 12/206:16 pm -
1 stop4h 37m
Deal found 10/25![American Airlines logo]()
$350
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:22 pm -
1 stop4h 47m
Tue 11/245:15 am -
1 stop5h 13m
Deal found 10/29![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:00 am -
1 stop5h 37m
Mon 12/73:20 pm -
2 stops7h 39m
Deal found 10/29![United Airlines logo]()
$368
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:33 am -
1 stop7h 06m
Sun 11/155:00 am -
1 stop4h 55m
Deal found 10/26![American Airlines logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:03 pm -
1 stop18h 30m
Sun 11/83:27 pm -
1 stop21h 42m
Deal found 10/27![Allegiant Air logo]()
$370
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/188:01 pm -
1 stop4h 57m
Sun 12/206:16 pm -
1 stop4h 37m
Deal found 10/25![American Airlines logo]()
$371
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:10 pm -
2 stops6h 56m
Sun 11/155:15 am -
1 stop3h 40m
Deal found 10/26![Delta logo]()
$374
Best flights from Knoxville to IowaDiscover carefully curated flight deals from Knoxville to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Knoxville to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:50 am -
1 stop5h 08m
Mon 12/78:00 am -
1 stop6h 26m
Deal found 10/29![American Airlines logo]()
$263
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:05 pm -
1 stop7h 37m
Tue 11/176:05 am -
1 stop6h 08m
Deal found 10/26![United Airlines logo]()
$313
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:30 pm -
1 stop5h 36m
Tue 11/245:15 am -
1 stop3h 40m
Deal found 10/25![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:30 pm -
1 stop5h 36m
Wed 11/255:15 am -
1 stop5h 13m
Deal found 10/25![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:40 pm -
1 stop6h 16m
Thu 11/268:03 am -
1 stop4h 47m
Deal found 10/27![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:30 pm -
1 stop5h 36m
Wed 11/255:15 am -
1 stop5h 13m
Deal found 10/25![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:20 am -
2 stops8h 54m
Mon 12/73:20 pm -
2 stops7h 39m
Deal found 10/29![United Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:30 pm -
1 stop5h 36m
Thu 11/2611:00 am -
2 stops7h 23m
Deal found 10/27![Delta logo]()
$344
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:40 pm -
1 stop5h 15m
Sat 11/143:15 pm -
1 stop4h 39m
Deal found 10/26![United Airlines logo]()
$387
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:10 pm -
1 stop5h 59m
Tue 11/1711:00 am -
2 stops10h 12m
Deal found 10/25![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:10 pm -
2 stops6h 56m
Sun 11/155:15 am -
1 stop3h 40m
Deal found 10/26![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:40 pm -
1 stop5h 15m
Tue 11/176:05 am -
2 stops7h 43m
Deal found 10/29![United Airlines logo]()
$442
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:04 am -
1 stop7h 04m
Sat 11/285:30 am -
1 stop4h 58m
Deal found 10/25![Delta logo]()
$432
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am -
1 stop8h 20m
Wed 11/119:55 am -
1 stop6h 04m
Deal found 10/27![United Airlines logo]()
$487
Last-minute flights from Knoxville to IowaDiscover last-minute flight deals from Knoxville to Iowa. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Iowa. Data last updated October 30, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:49 am -
1 stop5h 20m
Sun 11/86:15 am -
1 stop6h 02m
Deal found 10/25![American Airlines logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:03 pm -
1 stop18h 30m
Sun 11/83:27 pm -
1 stop21h 42m
Deal found 10/27![Allegiant Air logo]()
$370
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:40 pm -
1 stop5h 15m
Sat 11/143:15 pm -
1 stop4h 39m
Deal found 10/26![United Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:33 am -
1 stop7h 06m
Sun 11/155:00 am -
1 stop4h 55m
Deal found 10/26![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:10 pm -
2 stops6h 56m
Sun 11/155:15 am -
1 stop3h 40m
Deal found 10/26![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:05 pm -
1 stop7h 37m
Tue 11/176:05 am -
1 stop6h 08m
Deal found 10/26![United Airlines logo]()
$313
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:14 pm -
1 stop5h 12m
Tue 11/173:31 pm -
1 stop5h 08m
Deal found 10/26![American Airlines logo]()
$317
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:22 pm -
1 stop4h 47m
Tue 11/245:15 am -
1 stop5h 13m
Deal found 10/29![Delta logo]()
$354
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:05 am -
2 stops8h 10m
Tue 11/176:00 am -
2 stops12h 50m
Deal found 10/26![Southwest logo]()
$391
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:48 am -
1 stop6h 33m
Tue 11/246:00 am -
1 stop6h 26m
Deal found 10/27![American Airlines logo]()
$397
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:40 pm -
1 stop6h 16m
Thu 11/268:03 am -
1 stop4h 47m
Deal found 10/27![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:30 pm -
1 stop5h 36m
Thu 11/2611:00 am -
2 stops7h 23m
Deal found 10/27![Delta logo]()
$344
One-way flights from Knoxville to IowaSearch for one-way flight options from Knoxville to Iowa. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Knoxville to Iowa. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/108:30 am -
1 stop24h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Allegiant Air logo]()
$133
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:40 am -
1 stop6h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Delta logo]()
$159
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1712:50 pm -
2 stops11h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Southwest logo]()
$164
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:07 pm -
1 stop6h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![American Airlines logo]()
$180
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:10 pm -
1 stop5h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![American Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/109:30 pm -
2 stops20h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$253
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/115:05 pm -
1 stop5h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Delta logo]()
$264
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/114:09 pm -
1 stop8h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![American Airlines logo]()
$284
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:07 pm -
1 stop6h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Delta logo]()
$294
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:20 am -
2 stops11h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![United Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:35 pm -
2 stops15h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![United Airlines logo]()
$518
Find flight deals from Knoxville to Iowa
Keep the following information in mind while searching for Knoxville to Iowa flight deals. Data was last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $263 (American Airlines) |
One-way from | $133 (Kiwi.com) |
Popular in | March |
Cheapest in | February |
Average price | $561 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Knoxville to Iowa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleDes Moines
TYS Knoxville McGhee Tyson - DSM Des Moines
TYSDSM
Knoxville McGhee Tyson
Thu 12/17
5:40 am-10:53 am
1 stop6h 13m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$159
KnoxvilleDes Moines
TYS Knoxville McGhee Tyson - DSM Des Moines
TYSDSM
Knoxville McGhee Tyson
Fri 12/18
3:45 pm-11:35 pm
2 stops8h 50m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$164
KnoxvilleCedar Rapids
TYS Knoxville McGhee Tyson - CID Cedar Rapids
TYSCID
Knoxville McGhee Tyson
Sun 1/10
9:30 pm-5:28 pm
2 stops20h 58m
Cedar Rapids
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$253
KnoxvilleDes Moines
TYS Knoxville McGhee Tyson - DSM Des Moines
TYSDSM
Knoxville McGhee Tyson
Thu 12/3
6:50 am-10:58 am
1 stop5h 08m
Des Moines
Mon 12/7
8:00 am-3:26 pm
1 stop6h 26m
$263
KnoxvilleCedar Rapids
TYS Knoxville McGhee Tyson - CID Cedar Rapids
TYSCID
Knoxville McGhee Tyson
Sun 4/11
5:05 pm-9:51 pm
1 stop5h 46m
Cedar Rapids
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$264
Quickest round-trip
KnoxvilleCedar Rapids
TYS Knoxville McGhee Tyson - CID Cedar Rapids
TYSCID
Knoxville McGhee Tyson
Sun 11/22
6:30 pm-11:06 pm
1 stop5h 36m
Cedar Rapids
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$284
KnoxvilleDes Moines
TYS Knoxville McGhee Tyson - DSM Des Moines
TYSDSM
Knoxville McGhee Tyson
Thu 11/12
1:55 pm-9:55 pm
2 stops9h 00m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$299
KnoxvilleDes Moines
TYS Knoxville McGhee Tyson - DSM Des Moines
TYSDSM
Knoxville McGhee Tyson
Mon 11/16
5:05 pm-11:42 pm
1 stop7h 37m
Des Moines
Tue 11/17
6:05 am-1:13 pm
1 stop6h 08m
$313
KnoxvilleCedar Rapids
TYS Knoxville McGhee Tyson - CID Cedar Rapids
TYSCID
Knoxville McGhee Tyson
Mon 11/16
6:30 pm-11:06 pm
1 stop5h 36m
Cedar Rapids
Tue 11/24
5:15 am-9:55 am
1 stop3h 40m
$339
KnoxvilleCedar Rapids
TYS Knoxville McGhee Tyson - CID Cedar Rapids
TYSCID
Knoxville McGhee Tyson
Tue 11/17
6:30 pm-11:06 pm
1 stop5h 36m
Cedar Rapids
Wed 11/25
5:15 am-11:28 am
1 stop5h 13m
$339
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Iowa
Have a flexible travel schedule? Discover the best time to fly to Iowa from Knoxville with our price prediction graph.
TYS-DSM
TYS-CID
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Iowa
TYS-USIA
TYS-DSM
TYS-CID
What is the cheapest month to book a flight from Knoxville to Iowa?
Currently, February is the cheapest month in which you can book a flight from Knoxville to Iowa (average of $226). Flying from Knoxville to Iowa in March is currently the most expensive (average of $666). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Iowa
Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated October 30, 2026.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Knoxville to Iowa to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Food
6.7
Boarding
7.7
Overall
7.3
Entertainment
7.1
Crew
8.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Comfort
7.3
Food
6.7
Boarding
7.7
Overall
7.3
Entertainment
7.1
Crew
8.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Comfort
7.3
Food
6.7
Boarding
7.7
Overall
7.3
Entertainment
7.1
Crew
8.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Knoxville to Iowa
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Iowa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Iowa by cabin class
Find flights from Knoxville to Iowa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Iowa flights
Browse other Knoxville and Iowa flight options. Last updated on October 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Knoxville to Iowa flights
Consider these flights traveling from Knoxville to Iowa.
Top 2 airlines flying from Knoxville to Iowa
Discover the top 2 airlines that operate flights from Knoxville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$226 | Average$494 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$284 | Average$403 | FlexibilityNo cancel fee | On-time69% |