$138+ Cheap flights from Knoxville (TYS) to Iowa
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/7. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — DSM
Aug 3 — Aug 101
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Iowa with Cheapflights
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Cheapest flights from Knoxville to IowaExplore the most affordable flight options available from Knoxville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 4, 2026.
Explore the most affordable flight options available from Knoxville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 4, 2026.
This Frontier deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:19 pm
TYS
- OMA
1 stop23h 56m
Frontier
Tue 8/118:15 pm
OMA
- TYS
1 stop22h 09m
Frontier
Deal found 7/4![Frontier logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:56 pm
TYS
- DSM
1 stop7h 35m
Allegiant Air
Sat 8/811:13 am
DSM
- TYS
1 stop9h 50m
Allegiant Air
Deal found 6/30![Allegiant Air logo]()
$263
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/287:00 am
TYS
- DSM
1 stop8h 11m
American Airlines
Tue 8/42:41 pm
DSM
- TYS
1 stop5h 52m
American Airlines
Deal found 6/30![American Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:15 pm
TYS
- OMA
1 stop4h 58m
American Airlines
Sat 9/263:03 pm
OMA
- TYS
1 stop6h 47m
American Airlines
Deal found 6/30![American Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:08 pm
TYS
- DSM
1 stop14h 15m
Allegiant Air
Mon 8/1012:37 pm
DSM
- TYS
1 stop9h 35m
Allegiant Air
Deal found 7/4![Allegiant Air logo]()
$281
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:00 am
TYS
- DSM
1 stop5h 17m
United Airlines
Tue 8/46:00 am
DSM
- TYS
2 stops7h 27m
United Airlines
Deal found 6/30![United Airlines logo]()
$284
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:40 pm
TYS
- OMA
1 stop6h 00m
Southwest
Tue 8/1110:30 am
OMA
- TYS
2 stops7h 25m
Southwest
Deal found 7/1![Southwest logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:04 am
TYS
- DSM
1 stop8h 01m
Allegiant Air
Mon 9/144:59 pm
DSM
- TYS
1 stop15h 40m
Allegiant Air
Deal found 6/30![Allegiant Air logo]()
$289
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:22 pm
TYS
- DSM
1 stop4h 17m
Delta
Thu 8/132:45 pm
DSM
- TYS
1 stop7h 15m
Delta
Deal found 7/1![Delta logo]()
$299
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:13 pm
TYS
- OMA
1 stop6h 12m
American Airlines
Mon 10/195:34 pm
OMA
- TYS
1 stop5h 21m
American Airlines
Deal found 7/2![American Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:00 am
TYS
- DSM
1 stop4h 26m
United Airlines
Thu 8/131:21 pm
DSM
- TYS
2 stops9h 38m
United Airlines
Deal found 7/1![United Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:45 am
TYS
- DSM
2 stops16h 34m
Multiple Airlines
Sat 8/811:13 am
DSM
- TYS
1 stop9h 50m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$306
Best flights from Knoxville to IowaDiscover carefully curated flight deals from Knoxville to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 4, 2026.
Discover carefully curated flight deals from Knoxville to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 4, 2026.
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:40 am
TYS
- OMA
1 stop4h 32m
Delta
Tue 8/48:05 am
OMA
- TYS
1 stop7h 36m
Delta
Deal found 7/1![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:45 pm
TYS
- OMA
2 stops10h 00m
Southwest
Sat 9/2612:50 pm
OMA
- TYS
1 stop3h 50m
Southwest
Deal found 7/1![Southwest logo]()
$284
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:00 am
TYS
- DSM
1 stop4h 26m
United Airlines
Thu 8/131:21 pm
DSM
- TYS
2 stops9h 38m
United Airlines
Deal found 7/2![United Airlines logo]()
$304
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:05 pm
TYS
- MLI
2 stops7h 03m
American Airlines
Sun 8/166:00 am
MLI
- TYS
1 stop4h 06m
American Airlines
Deal found 7/3![American Airlines logo]()
$314
This Southwest deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:40 pm
TYS
- OMA
1 stop6h 00m
Southwest
Wed 7/295:20 am
OMA
- TYS
2 stops10h 40m
Southwest
Deal found 6/29![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:22 pm
TYS
- DSM
1 stop4h 17m
Delta
Thu 8/132:45 pm
DSM
- TYS
1 stop7h 15m
Delta
Deal found 7/2![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:00 am
TYS
- DSM
1 stop6h 20m
United Airlines
Sat 8/156:00 am
DSM
- TYS
2 stops7h 37m
United Airlines
Deal found 7/3![United Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:52 pm
TYS
- DSM
1 stop6h 28m
American Airlines
Tue 8/114:13 pm
DSM
- TYS
1 stop6h 05m
American Airlines
Deal found 7/3![American Airlines logo]()
$338
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:57 pm
TYS
- MLI
1 stop5h 33m
Delta
Wed 12/305:55 am
MLI
- TYS
1 stop6h 28m
Delta
Deal found 7/3![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2812:45 pm
TYS
- DSM
2 stops11h 05m
Southwest
Tue 8/46:10 am
DSM
- TYS
2 stops7h 10m
Southwest
Deal found 6/30![Southwest logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am
TYS
- OMA
1 stop6h 22m
American Airlines
Sun 10/45:34 pm
OMA
- TYS
1 stop5h 17m
American Airlines
Deal found 7/3![American Airlines logo]()
$338
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:00 am
TYS
- MLI
1 stop5h 04m
United Airlines
Mon 7/201:15 pm
MLI
- TYS
1 stop6h 29m
United Airlines
Deal found 7/1![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:40 am
TYS
- MLI
1 stop5h 45m
Delta
Sun 8/165:09 pm
MLI
- TYS
1 stop3h 51m
Delta
Deal found 7/3![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:05 pm
TYS
- OMA
1 stop7h 55m
Southwest
Mon 8/105:35 am
OMA
- TYS
2 stops5h 45m
Southwest
Deal found 7/2![Southwest logo]()
$324
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:35 am
TYS
- MLI
1 stop5h 48m
Delta
Mon 10/56:00 am
MLI
- TYS
1 stop4h 18m
Delta
Deal found 7/1![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:00 am
TYS
- DSM
1 stop5h 17m
United Airlines
Sat 8/86:00 am
DSM
- TYS
2 stops7h 27m
United Airlines
Deal found 7/3![United Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:50 pm
TYS
- DSM
2 stops9h 05m
Southwest
Mon 10/54:30 pm
DSM
- TYS
2 stops5h 10m
Southwest
Deal found 7/1![Southwest logo]()
$348
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:15 am
TYS
- OMA
1 stop7h 07m
Delta
Tue 8/41:41 pm
OMA
- TYS
1 stop5h 29m
Delta
Deal found 6/30![Delta logo]()
$318
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:40 pm
TYS
- DSM
1 stop7h 50m
United Airlines
Wed 9/28:00 am
DSM
- TYS
1 stop4h 18m
United Airlines
Deal found 6/30![United Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:40 am
TYS
- OMA
1 stop4h 48m
Delta
Thu 7/306:33 pm
OMA
- TYS
1 stop4h 19m
Delta
Deal found 6/29![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/276:32 pm
TYS
- LSE
1 stop6h 27m
American Airlines
Sat 8/112:01 pm
LSE
- TYS
2 stops8h 32m
American Airlines
Deal found 7/2![American Airlines logo]()
$442
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:00 am
TYS
- MLI
1 stop3h 54m
United Airlines
Wed 8/191:15 pm
MLI
- TYS
1 stop6h 38m
United Airlines
Deal found 6/29![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:35 am
TYS
- OMA
1 stop4h 54m
Delta
Sun 8/95:30 am
OMA
- TYS
1 stop4h 41m
Delta
Deal found 7/1![Delta logo]()
$357
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:32 pm
TYS
- MLI
1 stop7h 09m
American Airlines
Mon 7/2011:53 am
MLI
- TYS
2 stops9h 30m
American Airlines
Deal found 7/1![American Airlines logo]()
$539
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:09 pm
TYS
- MLI
1 stop4h 19m
American Airlines
Mon 10/56:00 am
MLI
- TYS
2 stops9h 18m
American Airlines
Deal found 7/1![American Airlines logo]()
$540
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/276:32 pm
TYS
- LSE
1 stop6h 27m
American Airlines
Fri 7/315:53 pm
LSE
- TYS
1 stop15h 58m
American Airlines
Deal found 7/1![American Airlines logo]()
$831
Last-minute flights from Knoxville to IowaDiscover last-minute flight deals from Knoxville to Iowa. Data last updated July 4, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Iowa. Data last updated July 4, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/287:00 am
TYS
- DSM
1 stop8h 11m
American Airlines
Tue 8/42:41 pm
DSM
- TYS
1 stop5h 52m
American Airlines
Deal found 6/30![American Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:32 pm
TYS
- OMA
1 stop7h 05m
American Airlines
Tue 8/116:14 am
OMA
- TYS
1 stop6h 17m
American Airlines
Deal found 7/1![American Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:00 am
TYS
- DSM
1 stop5h 17m
United Airlines
Tue 8/46:00 am
DSM
- TYS
2 stops7h 27m
United Airlines
Deal found 6/30![United Airlines logo]()
$284
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:40 pm
TYS
- OMA
1 stop6h 00m
Southwest
Tue 8/1110:30 am
OMA
- TYS
2 stops7h 25m
Southwest
Deal found 7/1![Southwest logo]()
$284
This Frontier deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:19 pm
TYS
- OMA
1 stop23h 56m
Frontier
Tue 8/118:15 pm
OMA
- TYS
1 stop22h 09m
Frontier
Deal found 7/4![Frontier logo]()
$249
This Booking.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:19 pm
TYS
- OMA
1 stop23h 56m
Frontier
Sun 8/98:00 pm
OMA
- TYS
1 stop22h 24m
Frontier
Deal found 7/4![Frontier logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:56 pm
TYS
- DSM
1 stop7h 35m
Allegiant Air
Sat 8/811:13 am
DSM
- TYS
1 stop9h 50m
Allegiant Air
Deal found 6/30![Allegiant Air logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:45 am
TYS
- DSM
2 stops16h 34m
Multiple Airlines
Sat 8/811:13 am
DSM
- TYS
1 stop9h 50m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:08 pm
TYS
- DSM
1 stop14h 15m
Allegiant Air
Mon 8/1012:37 pm
DSM
- TYS
1 stop9h 35m
Allegiant Air
Deal found 7/4![Allegiant Air logo]()
$281
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:22 pm
TYS
- DSM
1 stop4h 17m
Delta
Thu 8/132:45 pm
DSM
- TYS
1 stop7h 15m
Delta
Deal found 7/1![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:00 am
TYS
- DSM
1 stop4h 26m
United Airlines
Thu 8/131:21 pm
DSM
- TYS
2 stops9h 38m
United Airlines
Deal found 7/1![United Airlines logo]()
$304
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:40 am
TYS
- MLI
1 stop5h 45m
Delta
Sun 8/165:09 pm
MLI
- TYS
1 stop3h 51m
Delta
Deal found 7/3![Delta logo]()
$309
One-way flights from Knoxville to IowaSearch for one-way flight options from Knoxville to Iowa. Find affordable one-way fares based on user searches. Data last updated July 4, 2026.
Search for one-way flight options from Knoxville to Iowa. Find affordable one-way fares based on user searches. Data last updated July 4, 2026.
This Mytrip deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:19 pm
TYS
- OMA
1 stop23h 56m
Frontier
Deal found 7/4![Frontier logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/222:23 pm
TYS
- LSE
1 stop27h 17m
Allegiant Air
Deal found 7/1![Allegiant Air logo]()
$148
This American Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:07 pm
TYS
- DSM
1 stop7h 02m
American Airlines
Deal found 7/4![American Airlines logo]()
$180
This Southwest deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:35 pm
TYS
- DSM
2 stops12h 00m
Southwest
Deal found 7/4![Southwest logo]()
$190
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:40 am
TYS
- DSM
1 stop4h 33m
Delta
Deal found 6/30![Delta logo]()
$199
This Southwest deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:10 am
TYS
- OMA
2 stops7h 10m
Southwest
Deal found 7/4![Southwest logo]()
$204
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:32 pm
TYS
- DSM
1 stop6h 29m
American Airlines
Deal found 7/3![American Airlines logo]()
$219
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:40 am
TYS
- OMA
1 stop4h 48m
Delta
Deal found 6/30![Delta logo]()
$228
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/255:37 pm
TYS
- OMA
1 stop7h 12m
Delta
Deal found 7/1![Delta logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/27:00 am
TYS
- DSM
2 stops37h 04m
Multiple Airlines
Deal found 7/4![Multiple Airlines logo]()
$241
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/265:45 am
TYS
- DSM
2 stops9h 42m
United Airlines
Deal found 7/4![United Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:20 pm
TYS
- DSM
3 stops43h 14m
Multiple Airlines
Deal found 7/4![Multiple Airlines logo]()
$245
Find flight deals from Knoxville to Iowa
Keep the following information in mind while searching for Knoxville to Iowa flight deals. Data was last updated July 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $249 (Frontier) |
One-way from | $148 (Kiwi.com) |
Popular in | March |
Cheapest in | February |
Average price | $506 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 4, 2026.
Use the filters below to find and compare flights from Knoxville to Iowa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleOmaha
TYS - OMA
TYSOMA
Knoxville McGhee Tyson
Wed 7/29
6:40 am-10:12 am
1 stop4h 32m
Omaha Eppley Airfield
Tue 8/4
8:05 am-4:41 pm
1 stop7h 36m
$279
KnoxvilleOmaha
TYS - OMA
TYSOMA
Knoxville McGhee Tyson
Wed 9/23
12:45 pm-9:45 pm
2 stops10h 00m
Omaha Eppley Airfield
Sat 9/26
12:50 pm-5:40 pm
1 stop3h 50m
$284
KnoxvilleOmaha
TYS - OMA
TYSOMA
Knoxville McGhee Tyson
Tue 7/28
5:40 pm-10:40 pm
1 stop6h 00m
Omaha Eppley Airfield
Wed 7/29
5:20 am-5:00 pm
2 stops10h 40m
$284
KnoxvilleDes Moines
TYS - DSM
TYSDSM
Knoxville McGhee Tyson
Tue 8/11
5:22 pm-8:39 pm
1 stop4h 17m
Des Moines
Thu 8/13
2:45 pm-11:00 pm
1 stop7h 15m
$299
KnoxvilleDes Moines
TYS - DSM
TYSDSM
Knoxville McGhee Tyson
Tue 8/11
7:00 am-10:26 am
1 stop4h 26m
Des Moines
Thu 8/13
1:21 pm-11:59 pm
2 stops9h 38m
$304
KnoxvilleMoline
TYS - MLI
TYSMLI
Knoxville McGhee Tyson
Wed 12/23
5:57 pm-10:30 pm
1 stop5h 33m
Moline Quad-City
Wed 12/30
5:55 am-1:23 pm
1 stop6h 28m
$309
KnoxvilleDes Moines
TYS - DSM
TYSDSM
Knoxville McGhee Tyson
Tue 7/28
12:45 pm-10:50 pm
2 stops11h 05m
Des Moines
Tue 8/4
6:10 am-2:20 pm
2 stops7h 10m
$309
KnoxvilleMoline
TYS - MLI
TYSMLI
Knoxville McGhee Tyson
Wed 8/12
5:40 am-10:25 am
1 stop5h 45m
Moline Quad-City
Sun 8/16
5:09 pm-10:00 pm
1 stop3h 51m
$309
KnoxvilleMoline
TYS - MLI
TYSMLI
Knoxville McGhee Tyson
Thu 10/1
5:35 am-10:23 am
1 stop5h 48m
Moline Quad-City
Mon 10/5
6:00 am-11:18 am
1 stop4h 18m
$309
KnoxvilleMoline
TYS - MLI
TYSMLI
Knoxville McGhee Tyson
Wed 8/12
6:05 pm-12:08 am
2 stops7h 03m
Moline Quad-City
Sun 8/16
6:00 am-11:06 am
1 stop4h 06m
$314
Showing 1-10 of 41 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Iowa
Have a flexible travel schedule? Discover the best time to fly to Iowa from Knoxville with our price prediction graph.
TYS-OMA
TYS-LSE
TYS-DSM
TYS-MLI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Iowa
TYS-USIA
TYS-OMA
TYS-LSE
TYS-DSM
TYS-MLI
What is the cheapest month to book a flight from Knoxville to Iowa?
Currently, November is the cheapest month in which you can book a flight from Knoxville to Iowa (average of $203). Flying from Knoxville to Iowa in March is currently the most expensive (average of $428). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Iowa
Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated July 4, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Knoxville to Iowa to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Iowa
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Complete your trip
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Knoxville and Iowa flights
Browse other Knoxville and Iowa flight options. Last updated on July 4, 2026.
Popular flight searches
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Knoxville to Iowa flights
Consider these flights traveling from Knoxville to Iowa.
Top 3 airlines flying from Knoxville to Iowa
Discover the top 3 airlines that operate flights from Knoxville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$226 | Average$413 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$338 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$341 | Average$404 | FlexibilityNo cancel fee | On-time69% |