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$126+ Cheap flights from Knoxville (TYS) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/9. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — DSM
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Knoxville to Iowa

Keep the following information in mind while searching for Knoxville to Iowa flight deals. Data was last updated June 12, 2025.

Round-trip from

$226
(Mytrip)

One-way from

$126
(Delta)

Popular in

March

Cheapest in

August

Average price

$402
From Knoxville McGhee Tyson to Iowa
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One-way flight from Knoxville McGhee Tyson to Iowa
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Highest demand for flights based on searches. 18% potential increase in price ($82 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($32 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Knoxville to Iowa

Cheapest flights from Knoxville to Iowa
Explore the most affordable flight options available from Knoxville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/99:48 pmTYS - DSM
1 stop22h 16mAllegiant Air
Mon 7/145:04 pmDSM - TYS
1 stop23h 55mAllegiant Air
Deal found 6/11$226
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/246:19 pmTYS - DSM
1 stop5h 14mDelta
Wed 7/3011:24 amDSM - TYS
1 stop5h 00mDelta
Deal found 6/10$249
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/37:53 pmTYS - OMA
1 stop5h 41mAmerican Airlines
Mon 7/76:00 amOMA - TYS
1 stop6h 24mAmerican Airlines
Deal found 6/11$249
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/99:48 pmTYS - DSM
1 stop22h 16mMultiple Airlines
Wed 7/1611:00 amDSM - TYS
2 stops32h 04mMultiple Airlines
Deal found 6/11$258
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/257:53 pmTYS - DSM
1 stop4h 06mAmerican Airlines
Sun 6/291:17 pmDSM - TYS
1 stop6h 42mAmerican Airlines
Deal found 6/10$259
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/116:42 amTYS - OMA
1 stop6h 54mDelta
Fri 7/186:30 pmOMA - TYS
1 stop4h 29mDelta
Deal found 6/11$274
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/316:22 pmTYS - MLI
1 stop5h 54mAmerican Airlines
Sat 8/23:54 pmMLI - TYS
1 stop6h 58mAmerican Airlines
Deal found 6/11$279
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/146:00 amTYS - OMA
1 stop27h 01mAllegiant Air
Thu 7/179:56 amOMA - TYS
1 stop12h 41mAllegiant Air
Deal found 6/10$282
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/185:38 pmTYS - MLI
1 stop4h 49mUnited Airlines
Mon 6/233:47 pmMLI - TYS
1 stop5h 53mUnited Airlines
Deal found 6/11$324
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/134:52 pmTYS - OMA
1 stop7h 52mUnited Airlines
Mon 6/166:00 amOMA - TYS
1 stop6h 21mUnited Airlines
Deal found 6/11$339
This Mytrip deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/116:55 amTYS - OMA
3 stops29h 13mMultiple Airlines
Sat 7/197:25 pmOMA - TYS
1 stop26h 31mMultiple Airlines
Deal found 6/12$345
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/245:46 pmTYS - DSM
1 stop5h 01mUnited Airlines
Wed 7/303:38 pmDSM - TYS
2 stops7h 21mUnited Airlines
Deal found 6/11$394

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Knoxville to Iowa that are best for you.

Fly from

Knoxville

Fly to

Iowa

Route

Depart

Return

Price

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Wed 7/9

9:48 pm-7:04 pm

1 stop22h 16m

Des Moines

Mon 7/14

5:04 pm-5:59 pm

1 stop23h 55m

$226

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Thu 7/24

6:19 pm-10:33 pm

1 stop5h 14m

Des Moines

Wed 7/30

11:24 am-5:24 pm

1 stop5h 00m

$249

KnoxvilleOmaha

TYS - OMA

TYSOMA

Knoxville McGhee Tyson

Thu 7/3

7:53 pm-12:34 am

1 stop5h 41m

Omaha Eppley Airfield

Mon 7/7

6:00 am-1:24 pm

1 stop6h 24m

$249

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Wed 7/9

9:48 pm-7:04 pm

1 stop22h 16m

Des Moines

Wed 7/16

11:00 am-8:04 pm

2 stops32h 04m

$258

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Wed 6/25

7:53 pm-10:59 pm

1 stop4h 06m

Des Moines

Sun 6/29

1:17 pm-8:59 pm

1 stop6h 42m

$259

KnoxvilleOmaha

TYS - OMA

TYSOMA

Knoxville McGhee Tyson

Fri 7/11

6:42 am-12:36 pm

1 stop6h 54m

Omaha Eppley Airfield

Fri 7/18

6:30 pm-11:59 pm

1 stop4h 29m

$274

KnoxvilleMoline

TYS - MLI

TYSMLI

Knoxville McGhee Tyson

Thu 7/31

6:22 pm-11:16 pm

1 stop5h 54m

Moline Quad-City

Sat 8/2

3:54 pm-11:52 pm

1 stop6h 58m

$279

KnoxvilleOmaha

TYS - OMA

TYSOMA

Knoxville McGhee Tyson

Mon 7/14

6:00 am-8:01 am

1 stop27h 01m

Omaha Eppley Airfield

Thu 7/17

9:56 am-11:37 pm

1 stop12h 41m

$282

KnoxvilleOmaha

TYS - OMA

TYSOMA

Knoxville McGhee Tyson

Fri 7/11

6:55 am-11:08 am

3 stops29h 13m

Omaha Eppley Airfield

Sat 7/19

7:25 pm-10:56 pm

1 stop26h 31m

$345

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Thu 7/24

5:46 pm-9:47 pm

1 stop5h 01m

Des Moines

Wed 7/30

3:38 pm-11:59 pm

2 stops7h 21m

$394

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Showing 1-10 of 22 results
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Best time to book a flight from Knoxville to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Iowa

What is the cheapest month to book a flight from Knoxville to Iowa?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Iowa (average of $336). Flying from Knoxville to Iowa in June is currently the most expensive (average of $411). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to IA?

Find hourly flight availability from Knoxville to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

When flying from Knoxville to Iowa, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Iowa by month

Plan your trip to Iowa by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Iowa ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Iowa when rainfall is around 1.0 in.

Temperature in Iowa by month

Plan your trip to Iowa by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Iowa, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated June 12, 2025.
Read through reviews of airlines operating flights from Knoxville to Iowa, such as Delta, United Airlines and Allegiant Air. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Allegiant Air
7.3
Good
725 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Iowa?

    If you book a flight to Iowa from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • What are the cheapest airlines to fly from Knoxville to Iowa one-way?

    $126 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on United Airlines and Allegiant Air, with prices starting from $161 and $165, respectively.

  • What are the most popular routes from Knoxville to Iowa?

    The most popular route from Knoxville to Iowa is Knoxville McGhee Tyson - Omaha Eppley Airfield. You may also consider Knoxville McGhee Tyson - Des Moines or Knoxville McGhee Tyson - Moline Quad-City.

  • Can I find deals for flights from Knoxville to Iowa that include hotel bookings?

    Yes. In addition to deals on Knoxville to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Iowa.

  • Can I find deals for business class flights from Knoxville to Iowa?

    Yes. Cheapflights offers flight deals from Knoxville to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Iowa?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Iowa (average of $336). Flying from Knoxville to Iowa in June is currently the most expensive (average of $411). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Knoxville to Iowa

Discover the top 3 airlines that operate flights from Knoxville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$208Average$330FlexibilityNo cancel feeOn-time71%
DeltaCheapest$222Average$283FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$393FlexibilityNo cancel feeOn-time69%

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