What is the cheapest airline to fly from Santo Domingo to Indianapolis round-trip?

Spirit Airlines, at $382, was found to be the cheapest airline from Santo Domingo to Indianapolis.. Spirit Airlines is currently priced 44% below the average price you’ll pay for this route.

What is the cheapest day to fly from Santo Domingo to Indianapolis?

Travelers seeking maximum savings on their Santo Domingo to Indianapolis flight should consider departing on Thursday afternoons when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Indianapolis ranges from 2.3 - 5.1 inches per month. May is typically the wettest month, when rainfall can reach 5.1 in. February is typically the driest time to visit Indianapolis when rainfall is around 2.3 in.

If weather is an important factor for your trip to Indianapolis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

What are the most popular airlines that fly from Santo Domingo to Indianapolis?

The most popular airlines flying from Santo Domingo to Indianapolis are Delta, Spirit Airlines and United Airlines. Something to consider prior to booking your flight.

What is the cheapest day to fly round-trip from Santo Domingo to Indianapolis?

Flying to your destination on a Sunday can be more expensive, but this shouldn’t discourage you from finding affordable options to get to Indianapolis. Check prices with Cheapflights to find a great deal for your trip.

What is the cheapest month to fly from Santo Domingo to Indianapolis?

September is one of the best times of the year to fly to Indianapolis from Santo Domingo. Prices for September average $684 per person but you can even find prices for as low as $321. The most expensive prices can be found in the month of March. Opting for a September flight can save you 246% on your journey compared to booking in March

Can I find deals for flights from Santo Domingo to Indianapolis that include hotel bookings?

Yes. In addition to deals on Santo Domingo to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santo Domingo to Indianapolis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Indianapolis.

Can I find deals for business class flights from Santo Domingo to Indianapolis?

Yes. Cheapflights offers flight deals from Santo Domingo to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$174+ Flights from Santo Domingo to Indianapolis

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Cheap flight deals from Santo Domingo to Indianapolis

Round-trip from	$382 (SmartFares)
One-way from	$174 (Cheapflightsfares)
Popular in	March
Cheapest in	September
Average price	$491

From Santo Domingo Las Americas to Indianapolis

Search Deals

One-way flight from Santo Domingo Las Americas to Indianapolis

Search Deals

Highest demand for flights based on searches. 40% potential increase in price ($465 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 28% potential price decrease ($154 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in August 2025

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Find flight deals from Santo Domingo to Indianapolis

Cheapest flights from Santo Domingo to Indianapolis
Explore the most affordable flight options available from Santo Domingo to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2025.

Thu 11/66:55 pmSDQ - IND

1 stop29h 01mSpirit Airlines

Sun 11/161:28 pmIND - SDQ

2 stops27h 22mSpirit Airlines

Deal found 8/10

$382

Fri 10/105:00 pmSDQ - IND

1 stop17h 43mSpirit Airlines

Mon 10/136:35 pmIND - SDQ

1 stop20h 21mSpirit Airlines

Deal found 8/10

$383

Thu 8/141:48 amSDQ - IND

1 stop12h 56mMultiple Airlines

Mon 8/256:15 amIND - SDQ

1 stop5h 41mMultiple Airlines

Deal found 8/11

$428

Mon 8/185:05 pmSDQ - IND

1 stop18h 25mSpirit Airlines

Tue 8/263:05 pmIND - SDQ

1 stop24h 55mSpirit Airlines

Deal found 8/11

$449

Fri 10/36:18 amSDQ - IND

1 stop13h 55mMultiple Airlines

Fri 10/103:34 pmIND - SDQ

2 stops23h 08mMultiple Airlines

Deal found 8/10

$460

Best flights from Santo Domingo to Indianapolis
Discover carefully curated flight deals from Santo Domingo to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 11, 2025.

Thu 11/66:55 pmSDQ - IND

1 stop29h 01mSpirit Airlines

Sun 11/161:28 pmIND - SDQ

2 stops27h 22mSpirit Airlines

Deal found 8/10

$382

Fri 10/36:18 amSDQ - IND

1 stop13h 55mMultiple Airlines

Fri 10/103:34 pmIND - SDQ

2 stops23h 08mMultiple Airlines

Deal found 8/10

$460

Fri 10/105:00 pmSDQ - IND

1 stop17h 43mSpirit Airlines

Mon 10/136:35 pmIND - SDQ

1 stop20h 21mSpirit Airlines

Deal found 8/10

$383

Mon 1/196:39 pmSDQ - IND

2 stops46h 03mMultiple Airlines

Sat 1/315:49 amIND - SDQ

1 stop18h 50mMultiple Airlines

Deal found 8/10

$464

Fri 10/1010:19 amSDQ - IND

3 stops36h 52mMultiple Airlines

Mon 10/139:09 pmIND - SDQ

2 stops17h 47mMultiple Airlines

Deal found 8/10

$483

Fri 10/35:05 pmSDQ - IND

1 stop17h 48mSpirit Airlines

Fri 10/106:35 pmIND - SDQ

1 stop20h 07mSpirit Airlines

Deal found 8/10

$495

Thu 2/58:01 amSDQ - IND

2 stops15h 55mSpirit Airlines

Thu 2/196:35 amIND - SDQ

1 stop10h 15mSpirit Airlines

Deal found 8/10

$498

Last-minute flights from Santo Domingo to Indianapolis
Discover last-minute flight deals from Santo Domingo to Indianapolis. Data last updated August 11, 2025 and is based on user searches.

Thu 8/141:48 amSDQ - IND

1 stop12h 56mMultiple Airlines

Mon 8/256:15 amIND - SDQ

1 stop5h 41mMultiple Airlines

Deal found 8/11

$428

Fri 8/151:01 pmSDQ - IND

1 stop9h 15mSpirit Airlines

Mon 8/256:15 amIND - SDQ

1 stop5h 41mSpirit Airlines

Deal found 8/11

$478

Sun 8/171:48 amSDQ - IND

1 stop12h 56mMultiple Airlines

Tue 8/263:05 pmIND - SDQ

2 stops20h 51mMultiple Airlines

Deal found 8/11

$529

Mon 8/185:05 pmSDQ - IND

1 stop18h 25mSpirit Airlines

Tue 8/263:05 pmIND - SDQ

1 stop24h 55mSpirit Airlines

Deal found 8/11

$449

Mon 9/15:05 pmSDQ - IND

1 stop18h 25mSpirit Airlines

Mon 9/85:06 pmIND - SDQ

1 stop22h 54mSpirit Airlines

Deal found 8/11

$518

One-way flights from Santo Domingo to Indianapolis
Search for one-way flight options from Santo Domingo to Indianapolis. Find affordable one-way fares based on user searches. Data last updated August 11, 2025.

Wed 9/35:05 pmSDQ - IND

1 stop17h 48mSpirit Airlines

Deal found 8/10

$174

Wed 8/275:05 pmSDQ - IND

1 stop18h 25mSpirit Airlines

Deal found 8/10

$184

Wed 12/247:00 amSDQ - IND

1 stop14h 44mDelta

Deal found 8/11

$355

Thu 11/277:10 pmSDQ - IND

2 stops26h 16mMultiple Airlines

Deal found 8/10

$363

Wed 12/316:45 amSDQ - IND

2 stops16h 17mAmerican Airlines

Deal found 8/11

$369

Wed 12/317:00 amSDQ - IND

1 stop14h 44mDelta

Deal found 8/11

$434

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santo Domingo to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Thu 11/6

6:55 pm-10:56 pm

1 stop29h 01m

Indianapolis

Sun 11/16

1:28 pm-5:50 pm

2 stops27h 22m

$382

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Fri 10/10

5:00 pm-10:43 am

1 stop17h 43m

Indianapolis

Mon 10/13

6:35 pm-2:56 pm

1 stop20h 21m

$383

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Fri 10/3

6:18 am-8:13 pm

1 stop13h 55m

Indianapolis

Fri 10/10

3:34 pm-2:42 pm

2 stops23h 08m

$460

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Mon 1/19

6:39 pm-3:42 pm

2 stops46h 03m

Indianapolis

Sat 1/31

5:49 am-1:39 am

1 stop18h 50m

$464

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Fri 10/10

10:19 am-11:11 pm

3 stops36h 52m

Indianapolis

Mon 10/13

9:09 pm-2:56 pm

2 stops17h 47m

$483

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Fri 10/3

5:05 pm-10:53 am

1 stop17h 48m

Indianapolis

Fri 10/10

6:35 pm-2:42 pm

1 stop20h 07m

$495

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Thu 2/5

8:01 am-10:56 pm

2 stops15h 55m

Indianapolis

Thu 2/19

6:35 am-5:50 pm

1 stop10h 15m

$498

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Wed 9/3

5:05 pm-10:53 am

1 stop17h 48m

$174

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Wed 8/27

5:05 pm-11:30 am

1 stop18h 25m

$184

Santo DomingoIndianapolis

SDQ - IND

SDQIND

Santo Domingo Las Americas

Wed 12/24

7:00 am-8:44 pm

1 stop14h 44m

$355

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/10

Showing 1-10 of 13 results

Best time to book a flight from Santo Domingo to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Santo Domingo with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Indianapolis

What is the cheapest month to book a flight from Santo Domingo to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from Santo Domingo to Indianapolis (average of $297). Flying from Santo Domingo to Indianapolis in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to IND?

It’s typically best to fly out from Santo Domingo to Indianapolis in the afternoon. Doing so could potentially save you 41% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Indianapolis

Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Santo Domingo to Indianapolis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,978 reviews

Reviews

1 / 20

6.0

Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

Delta

8.0

Very good

7,978 reviews

Delta

8.0

Very good

7,978 reviews

Reviews

1 / 20

6.0

Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

United Airlines

7.4

Good

8,922 reviews

Delta

8.0

Very good

7,978 reviews

Reviews

1 / 20

6.0

Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,978 reviews

Reviews

1 / 20

6.0

Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

Spirit Airlines

6.3

Okay

8,043 reviews

Delta

8.0

Very good

7,978 reviews

Reviews

1 / 20

6.0

Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

Related info for your journey

What is the cheapest airline to fly from Santo Domingo to Indianapolis round-trip?
Spirit Airlines, at $382, was found to be the cheapest airline from Santo Domingo to Indianapolis.. Spirit Airlines is currently priced 44% below the average price you’ll pay for this route.
Can I find deals for flights from Santo Domingo to Indianapolis that include hotel bookings?
Yes. In addition to deals on Santo Domingo to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santo Domingo to Indianapolis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Indianapolis.
Can I find deals for business class flights from Santo Domingo to Indianapolis?
Yes. Cheapflights offers flight deals from Santo Domingo to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santo Domingo to Indianapolis?
Currently, August is the cheapest month in which you can book a flight from Santo Domingo to Indianapolis (average of $297). Flying from Santo Domingo to Indianapolis in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Greenwood

Bloomington

Noblesville

Muncie

Fishers

Terre Haute

Anderson

Kokomo

Franklin

Plainfield

Carmel

Crawfordsville

Shelbyville

Speedway

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Santo Domingo to Indianapolis

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$326	Average$449	FlexibilityNo cancel fee	On-time65%
Delta	Cheapest$416	Average$635	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$429	Average$796	FlexibilityNo cancel fee	On-time69%

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$174+ Cheap flights from Santo Domingo (SDQ) to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/3. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santo Domingo to Indianapolis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Santo Domingo to Indianapolis

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Santo Domingo to Indianapolis

Cheapest flights from Santo Domingo to IndianapolisExplore the most affordable flight options available from Santo Domingo to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2025.

Explore the most affordable flight options available from Santo Domingo to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santo Domingo to Indianapolis that are best for you.

Best time to book a flight from Santo Domingo to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Santo Domingo with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Indianapolis

What is the cheapest month to book a flight from Santo Domingo to Indianapolis?

What is the cheapest time of day to fly from SDQ to IND?

Find hourly flight availability from Santo Domingo to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 11, 2025.

Reviews of airlines servicing Indianapolis

Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Santo Domingo to Indianapolis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What is the cheapest airline to fly from Santo Domingo to Indianapolis round-trip?

Can I find deals for flights from Santo Domingo to Indianapolis that include hotel bookings?

How can I find direct flights from Santo Domingo to Indianapolis?

Can I find deals for business class flights from Santo Domingo to Indianapolis?

What is the cheapest month to book a flight from Santo Domingo to Indianapolis?

Traveling to a place near Indianapolis?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Santo Domingo to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Santo Domingo to Indianapolis

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Cheapest flights from Santo Domingo to Indianapolis
Explore the most affordable flight options available from Santo Domingo to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2025.