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$333+ Cheap flights from La Crosse to Indianapolis (LSE - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/21. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — IND
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from La Crosse to Indianapolis

Cheapest flights from La Crosse to Indianapolis
Explore the most affordable flight options available from La Crosse to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:00 am
LSE
-
IND
1 stop3h 18m
American Airlines
Sat 4/2512:30 pm
IND
-
LSE
1 stop6h 32m
American Airlines
Deal found 1/26$434
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:25 pm
LSE
-
IND
1 stop4h 42m
American Airlines
Tue 6/98:30 pm
IND
-
LSE
1 stop4h 29m
American Airlines
Deal found 1/27$488
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:20 am
LSE
-
IND
2 stops8h 15m
American Airlines
Tue 2/245:35 am
IND
-
LSE
1 stop4h 43m
American Airlines
Deal found 1/27$500
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:20 am
LSE
-
IND
2 stops10h 19m
American Airlines
Mon 2/237:04 am
IND
-
LSE
1 stop4h 57m
American Airlines
Deal found 1/27$543
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2111:27 am
LSE
-
IND
2 stops9h 46m
American Airlines
Sun 2/2210:23 am
IND
-
LSE
2 stops8h 36m
American Airlines
Deal found 1/27$548

Find flight deals from La Crosse to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from La Crosse (LSE) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$434
(American Airlines)

One-way from

$333
(American Airlines)
Provider with most accurate pricing for La Crosse-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for La Crosse-Indianapolis flights.
Search Deals
From La Crosse to Indianapolis
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One-way flight from La Crosse to Indianapolis
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Cheapflights Fare Finder

 
Customize your flight search to find flights from La Crosse to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from La Crosse to Indianapolis that are best for you.

Fly from

La Crosse

Fly to

Indianapolis

Route

Depart

Return

Price

La CrosseIndianapolis

LSE - IND

LSEIND

La Crosse

Tue 4/21

6:32 pm-12:24 am

1 stop4h 52m

Indianapolis

Sat 4/25

6:10 am-9:35 am

1 stop4h 25m

$434

La CrosseIndianapolis

LSE - IND

LSEIND

La Crosse

Mon 6/1

5:25 pm-11:07 pm

1 stop4h 42m

Indianapolis

Tue 6/9

8:30 pm-11:59 pm

1 stop4h 29m

$488

La CrosseIndianapolis

LSE - IND

LSEIND

La Crosse

Sat 2/21

5:20 am-2:35 pm

2 stops8h 15m

Indianapolis

Tue 2/24

5:35 am-9:18 am

1 stop4h 43m

$500

La CrosseIndianapolis

LSE - IND

LSEIND

La Crosse

Sat 3/21

5:09 am-1:25 pm

1 stop7h 16m

$333

La CrosseIndianapolis

LSE - IND

LSEIND

La Crosse

Mon 4/20

6:00 am-10:18 am

1 stop3h 18m

$429

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Compare providers for flights from La Crosse to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from La Crosse to Indianapolis in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on La Crosse-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on La Crosse-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from La Crosse-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on La Crosse-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for La Crosse-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from La Crosse to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from La Crosse to Indianapolis

What is the cheapest month to book a flight from La Crosse to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from La Crosse to Indianapolis (average of $248). Flying from La Crosse to Indianapolis in March is currently the most expensive (average of $716). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from La Crosse to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from La Crosse to Indianapolis?

    There are many flights that can get you from La Crosse to Indianapolis in 4h 52m. Fly via American Airlines to get the fastest option. Airlines will cover a distance of 384 mi.

  • Can I find deals for flights from La Crosse to Indianapolis that include hotel bookings?

    Yes. In addition to deals on La Crosse to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from La Crosse to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from La Crosse to Indianapolis.

  • Can I find deals for business class flights from La Crosse to Indianapolis?

    Yes. Cheapflights offers flight deals from La Crosse to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from La Crosse to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from La Crosse to Indianapolis (average of $248). Flying from La Crosse to Indianapolis in March is currently the most expensive (average of $716). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Fishers
Noblesville
Greenwood
Plainfield
Anderson
Kokomo
Mooresville
Franklin
Carmel
Crawfordsville
Bloomington

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