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$165+ Cheap flights from South Padre Island, TX to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — IND
Mar 7 — Mar 141
Sat 3/7
Sat 3/14
1 adult, Economy
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Cheap flight deals from South Padre Island to Indiana

Cheapest flights from South Padre Island to Indiana
Explore the most affordable flight options available from South Padre Island to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.

This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/268:04 pm
BRO
-
ORD
1 stop4h 51m
American Airlines
Mon 3/25:00 am
ORD
-
BRO
1 stop5h 17m
American Airlines
Deal found 2/4$289
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/207:18 am
BRO
-
CVG
1 stop7h 18m
United Airlines
Tue 2/244:50 pm
CVG
-
BRO
1 stop5h 41m
United Airlines
Deal found 2/3$294
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:25 pm
BRO
-
ORD
1 stop5h 50m
United Airlines
Sun 7/126:30 am
ORD
-
BRO
1 stop4h 52m
United Airlines
Deal found 2/2$309
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/195:14 pm
BRO
-
CVG
1 stop5h 29m
United Airlines
Mon 2/234:50 pm
CVG
-
BRO
1 stop5h 41m
United Airlines
Deal found 2/4$309
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:44 pm
BRO
-
ORD
1 stop4h 52m
American Airlines
Thu 3/55:00 am
ORD
-
BRO
1 stop5h 17m
American Airlines
Deal found 2/2$329
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:04 pm
BRO
-
ORD
1 stop4h 51m
American Airlines
Tue 2/242:58 pm
ORD
-
BRO
1 stop8h 16m
American Airlines
Deal found 2/5$339
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/145:14 pm
BRO
-
ORD
1 stop7h 12m
United Airlines
Tue 2/245:45 am
ORD
-
BRO
1 stop5h 51m
United Airlines
Deal found 2/3$349
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/249:35 am
BRO
-
CVG
1 stop5h 01m
United Airlines
Sat 2/288:35 am
CVG
-
BRO
2 stops10h 27m
United Airlines
Deal found 2/2$364
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/157:18 am
BRO
-
ORD
1 stop5h 19m
United Airlines
Thu 2/2612:45 pm
ORD
-
BRO
1 stop5h 17m
United Airlines
Deal found 2/4$366
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:35 am
BRO
-
IND
1 stop28h 42m
Multiple Airlines
Sun 5/313:12 pm
IND
-
BRO
1 stop17h 43m
Multiple Airlines
Deal found 2/2$369
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:05 pm
BRO
-
ORD
1 stop7h 50m
United Airlines
Sat 5/912:40 pm
ORD
-
BRO
1 stop5h 48m
United Airlines
Deal found 2/2$369
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/113:18 pm
BRO
-
ORD
1 stop5h 21m
American Airlines
Sat 2/214:49 pm
ORD
-
BRO
1 stop6h 25m
American Airlines
Deal found 2/3$374

Find flight deals from South Padre Island to Indiana

Keep the following information in mind while searching for South Padre Island to Indiana flight deals. Data was last updated February 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$289
(American Airlines)

One-way from

$165
(United Airlines)

Popular in

September

Cheapest in

December

Average price

$434
Provider with most accurate pricing for Brownsville South Padre Is. Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Brownsville South Padre Is. Intl-Indianapolis flights.
Search Deals
From South Padre Island to Indiana
Search Deals
One-way flight from South Padre Island to Indiana
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($101 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Padre Island to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from South Padre Island to Indiana that are best for you.

Fly from

South Padre Island

Fly to

Indiana

Route

Depart

Return

Price

BrownsvilleChicago

BRO - ORD

BROORD

Brownsville South Padre Is. Intl

Thu 2/26

8:04 pm-12:55 am

1 stop4h 51m

Chicago O'Hare Intl

Mon 3/2

5:00 am-10:17 am

1 stop5h 17m

$289

BrownsvilleChicago

BRO - ORD

BROORD

Brownsville South Padre Is. Intl

Tue 3/3

6:44 pm-11:36 pm

1 stop4h 52m

Chicago O'Hare Intl

Tue 3/10

4:49 pm-10:54 pm

1 stop6h 05m

$289

BrownsvilleCincinnati

BRO - CVG

BROCVG

Brownsville South Padre Is. Intl

Fri 2/20

7:18 am-3:36 pm

1 stop7h 18m

Cincinnati Cinci./N. Kentucky

Tue 2/24

4:50 pm-9:31 pm

1 stop5h 41m

$294

BrownsvilleCincinnati

BRO - CVG

BROCVG

Brownsville South Padre Is. Intl

Thu 2/19

5:14 pm-11:43 pm

1 stop5h 29m

Cincinnati Cinci./N. Kentucky

Mon 2/23

4:50 pm-9:31 pm

1 stop5h 41m

$309

BrownsvilleCincinnati

BRO - CVG

BROCVG

Brownsville South Padre Is. Intl

Tue 2/24

7:18 am-3:36 pm

1 stop7h 18m

Cincinnati Cinci./N. Kentucky

Sat 2/28

8:35 am-6:02 pm

2 stops10h 27m

$364

BrownsvilleChicago

BRO - ORD

BROORD

Brownsville South Padre Is. Intl

Sun 2/15

7:18 am-12:37 pm

1 stop5h 19m

Chicago O'Hare Intl

Thu 2/26

12:45 pm-6:02 pm

1 stop5h 17m

$366

BrownsvilleIndianapolis

BRO - IND

BROIND

Brownsville South Padre Is. Intl

Fri 5/22

8:35 am-2:17 pm

1 stop28h 42m

Indianapolis

Sun 5/31

3:12 pm-7:55 am

1 stop17h 43m

$369

BrownsvilleChicago

BRO - ORD

BROORD

Brownsville South Padre Is. Intl

Sat 5/2

7:20 am-12:37 pm

1 stop5h 17m

Chicago O'Hare Intl

Tue 5/5

10:30 am-4:24 pm

1 stop5h 54m

$369

BrownsvilleChicago

BRO - ORD

BROORD

Brownsville South Padre Is. Intl

Thu 5/7

5:17 pm-12:45 am

1 stop7h 28m

Chicago O'Hare Intl

Sat 5/9

4:00 pm-9:59 pm

1 stop5h 59m

$369

BrownsvilleChicago

BRO - ORD

BROORD

Brownsville South Padre Is. Intl

Mon 5/4

5:17 pm-12:45 am

1 stop7h 28m

Chicago O'Hare Intl

Sat 5/9

10:30 am-6:28 pm

1 stop7h 58m

$369

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 36 results
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Best time to book a flight from South Padre Island to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from South Padre Island with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Padre Island to Indiana

What is the cheapest month to book a flight from South Padre Island to Indiana?

Currently, July is the cheapest month in which you can book a flight from South Padre Island to Indiana (average of $149). Flying from South Padre Island to Indiana in October is currently the most expensive (average of $320). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from South Padre Island to Indiana?

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated February 5, 2026.
Get a feel of what it's like to fly with American Airlines from South Padre Island to Indiana by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,237 reviews

Food

6.4

Comfort

7.2

Entertainment

6.9

Overall

7.2

Boarding

7.5

Crew

8.0

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation
American Airlines
7.2
Good
11,237 reviews
American Airlines
7.2
Good
11,237 reviews

Food

6.4

Comfort

7.2

Entertainment

6.9

Overall

7.2

Boarding

7.5

Crew

8.0

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation

Related info for your journey

Find useful and relevant information for your journey from South Padre Island to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Padre Island to Indiana?

    Airlines like American Airlines and United Airlines fly from South Padre Island to Indiana in about 4h 51m. The time it takes to get you to your destination can typically vary by up to 2h 27m. There are 1235 mi between South Padre Island and Indiana. This flight may include one or multiple stops.

  • What are the most popular routes from South Padre Island to Indiana?

    When deciding which route to take from South Padre Island to Indiana consider Brownsville South Padre Is. Intl - Chicago O'Hare Intl, Brownsville South Padre Is. Intl - Indianapolis or Brownsville South Padre Is. Intl - Cincinnati Cinci./N. Kentucky as they are the most popular.

  • Can I find deals for flights from South Padre Island to Indiana that include hotel bookings?

    Yes. In addition to deals on South Padre Island to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Padre Island to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Padre Island to Indiana.

  • Can I find deals for business class flights from South Padre Island to Indiana?

    Yes. Cheapflights offers flight deals from South Padre Island to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Padre Island to Indiana?

    Currently, July is the cheapest month in which you can book a flight from South Padre Island to Indiana (average of $149). Flying from South Padre Island to Indiana in October is currently the most expensive (average of $320). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Padre Island to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Padre Island to Indiana

Discover the top 2 airlines that operate flights from South Padre Island to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$194Average$402FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$276FlexibilityNo cancel feeOn-timeN/A

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