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$160+ Cheap flights from South Padre Island, TX to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/17. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — IND
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from South Padre Island to Indiana

Cheapest flights from South Padre Island to Indiana
Explore the most affordable flight options available from South Padre Island to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/252:58 pm
BRO
-
CVG
1 stop6h 43m
American Airlines
Wed 3/45:12 pm
CVG
-
BRO
1 stop7h 02m
American Airlines
Deal found 1/28$279
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/128:04 pm
BRO
-
ORD
1 stop4h 51m
American Airlines
Mon 2/165:00 am
ORD
-
BRO
1 stop5h 17m
American Airlines
Deal found 1/28$339
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:25 pm
BRO
-
ORD
1 stop7h 20m
United Airlines
Fri 6/269:25 am
ORD
-
BRO
1 stop6h 13m
United Airlines
Deal found 1/28$374
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2412:15 pm
BRO
-
IND
2 stops10h 29m
United Airlines
Sat 2/285:08 pm
IND
-
BRO
1 stop5h 23m
United Airlines
Deal found 1/26$419
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2412:15 pm
BRO
-
ORD
1 stop7h 38m
United Airlines
Sat 2/2812:45 pm
ORD
-
BRO
1 stop5h 17m
United Airlines
Deal found 1/26$424
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/259:35 am
BRO
-
CVG
2 stops11h 24m
United Airlines
Wed 3/411:17 am
CVG
-
BRO
2 stops7h 45m
United Airlines
Deal found 1/28$427
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/3010:53 am
BRO
-
ORD
1 stop4h 44m
American Airlines
Sun 2/86:54 am
ORD
-
BRO
1 stop7h 54m
American Airlines
Deal found 1/28$439
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/37:15 am
BRO
-
SDF
1 stop4h 59m
United Airlines
Sat 2/76:00 am
SDF
-
BRO
1 stop6h 31m
United Airlines
Deal found 1/27$479
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/35:25 pm
BRO
-
ORD
1 stop5h 34m
United Airlines
Sat 2/710:35 am
ORD
-
BRO
1 stop7h 27m
United Airlines
Deal found 1/27$489
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/289:30 am
BRO
-
CVG
1 stop5h 17m
United Airlines
Sun 2/111:41 am
CVG
-
BRO
1 stop5h 31m
United Airlines
Deal found 1/26$499
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:25 pm
BRO
-
ORD
1 stop7h 20m
United Airlines
Mon 5/256:30 am
ORD
-
BRO
1 stop4h 52m
United Airlines
Deal found 1/28$501
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2212:07 pm
BRO
-
ORD
1 stop19h 53m
United Airlines
Sun 5/245:30 am
ORD
-
BRO
1 stop5h 52m
United Airlines
Deal found 1/28$507

Find flight deals from South Padre Island to Indiana

Keep the following information in mind while searching for South Padre Island to Indiana flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$279
(American Airlines)

One-way from

$160
(United Airlines)

Popular in

September

Cheapest in

December

Average price

$261
Provider with most accurate pricing for Brownsville South Padre Is. Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Brownsville South Padre Is. Intl-Indianapolis flights.
Search Deals
From South Padre Island to Indiana
Search Deals
One-way flight from South Padre Island to Indiana
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($101 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Padre Island to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from South Padre Island to Indiana that are best for you.

Fly from

South Padre Island

Fly to

Indiana

Route

Depart

Return

Price

BrownsvilleCincinnati

BRO - CVG

BROCVG

Brownsville South Padre Is. Intl

Wed 2/25

2:58 pm-10:41 pm

1 stop6h 43m

Cincinnati Cinci./N. Kentucky

Wed 3/4

5:12 pm-11:14 pm

1 stop7h 02m

$279

BrownsvilleChicago

BRO - ORD

BROORD

Brownsville South Padre Is. Intl

Sat 2/14

2:58 pm-8:40 pm

1 stop5h 42m

Chicago O'Hare Intl

Mon 2/16

10:49 am-6:14 pm

1 stop7h 25m

$339

BrownsvilleChicago

BRO - ORD

BROORD

Brownsville South Padre Is. Intl

Thu 2/12

8:04 pm-12:55 am

1 stop4h 51m

Chicago O'Hare Intl

Mon 2/16

5:00 am-10:17 am

1 stop5h 17m

$339

BrownsvilleChicago

BRO - ORD

BROORD

Brownsville South Padre Is. Intl

Fri 6/19

5:25 pm-12:45 am

1 stop7h 20m

Chicago O'Hare Intl

Fri 6/26

9:25 am-3:38 pm

1 stop6h 13m

$374

BrownsvilleIndianapolis

BRO - IND

BROIND

Brownsville South Padre Is. Intl

Tue 2/24

12:15 pm-11:44 pm

2 stops10h 29m

Indianapolis

Sat 2/28

5:08 pm-9:31 pm

1 stop5h 23m

$419

BrownsvilleChicago

BRO - ORD

BROORD

Brownsville South Padre Is. Intl

Tue 2/24

12:15 pm-7:53 pm

1 stop7h 38m

Chicago O'Hare Intl

Sat 2/28

12:45 pm-6:02 pm

1 stop5h 17m

$424

BrownsvilleCincinnati

BRO - CVG

BROCVG

Brownsville South Padre Is. Intl

Wed 2/25

9:35 am-9:59 pm

2 stops11h 24m

Cincinnati Cinci./N. Kentucky

Wed 3/4

11:17 am-6:02 pm

2 stops7h 45m

$427

BrownsvilleChicago

BRO - ORD

BROORD

Brownsville South Padre Is. Intl

Fri 5/22

5:25 pm-12:45 am

1 stop7h 20m

Chicago O'Hare Intl

Mon 5/25

6:30 am-11:22 am

1 stop4h 52m

$501

BrownsvilleChicago

BRO - ORD

BROORD

Brownsville South Padre Is. Intl

Fri 5/22

12:07 pm-8:00 am

1 stop19h 53m

Chicago O'Hare Intl

Sun 5/24

5:30 am-11:22 am

1 stop5h 52m

$507

BrownsvilleChicago

BRO - ORD

BROORD

Brownsville South Padre Is. Intl

Thu 2/12

5:14 pm-11:04 pm

1 stop5h 50m

Chicago O'Hare Intl

Mon 2/16

5:45 am-11:36 am

1 stop5h 51m

$509

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 23 results
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Best time to book a flight from South Padre Island to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from South Padre Island with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Padre Island to Indiana

What is the cheapest month to book a flight from South Padre Island to Indiana?

Currently, July is the cheapest month in which you can book a flight from South Padre Island to Indiana (average of $149). Flying from South Padre Island to Indiana in February is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated January 29, 2026.
Get a feel of what it's like to fly with American Airlines from South Padre Island to Indiana by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,205 reviews

Entertainment

6.9

Crew

8.0

Comfort

7.2

Overall

7.2

Boarding

7.5

Food

6.4

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation
American Airlines
7.2
Good
11,205 reviews
American Airlines
7.2
Good
11,205 reviews

Entertainment

6.9

Crew

8.0

Comfort

7.2

Overall

7.2

Boarding

7.5

Food

6.4

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation

Related info for your journey

Find useful and relevant information for your journey from South Padre Island to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Padre Island to Indiana?

    Airlines like American Airlines and United Airlines fly from South Padre Island to Indiana in about 6h 43m. The time it takes to get you to your destination can typically vary by up to 37m. There are 1170 mi between South Padre Island and Indiana. This flight may include one or multiple stops.

  • What are the most popular routes from South Padre Island to Indiana?

    When deciding which route to take from South Padre Island to Indiana consider Brownsville South Padre Is. Intl - Chicago O'Hare Intl, Brownsville South Padre Is. Intl - Indianapolis or Brownsville South Padre Is. Intl - Cincinnati Cinci./N. Kentucky as they are the most popular.

  • Can I find deals for flights from South Padre Island to Indiana that include hotel bookings?

    Yes. In addition to deals on South Padre Island to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Padre Island to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Padre Island to Indiana.

  • Can I find deals for business class flights from South Padre Island to Indiana?

    Yes. Cheapflights offers flight deals from South Padre Island to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Padre Island to Indiana?

    Currently, July is the cheapest month in which you can book a flight from South Padre Island to Indiana (average of $149). Flying from South Padre Island to Indiana in February is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Padre Island to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Padre Island to Indiana

Discover the top 2 airlines that operate flights from South Padre Island to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$194Average$414FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$276FlexibilityNo cancel feeOn-timeN/A

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