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$387+ Cheap flights from Rome (ROM) to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/30. Fares are subject to change and may not be available on all flights or dates of travel.
ROM — IND
Apr 26 — May 31
Sun 4/26
Sun 5/3
1 adult, Economy
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Cheap flight deals from Rome to Indiana

Cheapest flights from Rome to Indiana
Explore the most affordable flight options available from Rome to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 27, 2026.

This eDestinos deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:45 pm
FCO
-
ORD
1 stop33h 30m
Icelandair
Tue 4/287:25 pm
ORD
-
FCO
1 stop12h 10m
Icelandair
Deal found 3/22$491
This Mytrip deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/103:45 pm
FCO
-
ORD
1 stop12h 40m
Icelandair
Sun 4/1910:25 pm
ORD
-
FCO
1 stop33h 10m
Icelandair
Deal found 3/25$523
This Mytrip deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/213:45 pm
FCO
-
ORD
1 stop33h 30m
Icelandair
Wed 6/310:25 pm
ORD
-
FCO
1 stop18h 10m
Icelandair
Deal found 3/22$539
This Gotogate deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/193:45 pm
FCO
-
ORD
1 stop12h 40m
Icelandair
Tue 5/267:25 pm
ORD
-
FCO
1 stop12h 10m
Icelandair
Deal found 3/23$540
This Gotogate deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/23:45 pm
FCO
-
ORD
1 stop33h 30m
Icelandair
Sun 5/1710:25 pm
ORD
-
FCO
1 stop33h 10m
Icelandair
Deal found 3/24$542
This FlightHub deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/263:45 pm
FCO
-
ORD
1 stop12h 40m
Icelandair
Sat 9/127:25 pm
ORD
-
FCO
1 stop12h 10m
Icelandair
Deal found 3/23$546
This Icelandair deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Icelandair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:45 pm
FCO
-
ORD
1 stop12h 40m
Icelandair
Mon 4/207:25 pm
ORD
-
FCO
1 stop12h 10m
Icelandair
Deal found 3/23$556
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:30 am
FCO
-
MDW
2 stops18h 28m
Delta
Sun 5/310:41 am
MDW
-
FCO
1 stop18h 54m
Delta
Deal found 3/27$657
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:30 am
FCO
-
MDW
2 stops17h 52m
Delta
Sun 4/122:05 pm
MDW
-
FCO
1 stop13h 00m
Delta
Deal found 3/23$658
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:30 am
FCO
-
MDW
2 stops19h 10m
Delta
Sun 4/199:27 am
MDW
-
FCO
2 stops17h 43m
Delta
Deal found 3/25$659
This KLM deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:00 am
FCO
-
MDW
1 stop15h 58m
Multiple Airlines
Sun 5/35:21 pm
MDW
-
FCO
1 stop12h 14m
Multiple Airlines
Deal found 3/27$664
This KLM deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/219:00 am
FCO
-
MDW
1 stop15h 58m
KLM
Tue 4/281:24 pm
MDW
-
FCO
1 stop14h 36m
KLM
Deal found 3/24$665

Find flight deals from Rome to Indiana

Keep the following information in mind while searching for Rome to Indiana flight deals. Data was last updated March 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$491
(eDestinos)

One-way from

$387
(Kiwi.com)
Provider with most accurate pricing for Rome (ROM)-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Rome (ROM)-Indianapolis flights.
Search Deals
From Rome (ROM) to Indiana
Search Deals
One-way flight from Rome (ROM) to Indiana
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Rome to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
Use the filters below to find and compare flights from Rome to Indiana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RomeChicago

FCO - ORD

FCOORD

Rome Fiumicino

Thu 8/27

3:45 pm-6:15 pm

1 stop33h 30m

Chicago O'Hare Intl

Fri 9/4

7:25 pm-2:35 pm

1 stop12h 10m

$573

RomeChicago

FCO - ORD

FCOORD

Rome Fiumicino

Wed 4/8

6:30 am-2:30 pm

1 stop15h 00m

Chicago O'Hare Intl

Sun 4/12

5:10 pm-4:35 pm

1 stop16h 25m

$650

RomeChicago

FCO - ORD

FCOORD

Rome Fiumicino

Tue 4/21

10:00 am-1:30 pm

Nonstop10h 30m

Chicago O'Hare Intl

Tue 4/28

5:55 pm-12:55 pm

1 stop12h 00m

$651

RomeChicago

FCO - ORD

FCOORD

Rome Fiumicino

Fri 9/18

10:30 am-5:50 pm

1 stop14h 20m

Chicago O'Hare Intl

Fri 10/2

5:55 pm-2:35 pm

1 stop13h 40m

$656
Quickest round-trip

RomeChicago

FCO - ORD

FCOORD

Rome Fiumicino

Fri 4/17

10:00 am-1:30 pm

Nonstop10h 30m

Chicago O'Hare Intl

Mon 4/20

4:55 pm-9:10 am

Nonstop9h 15m

$658

RomeChicago

FCO - MDW

FCOMDW

Rome Fiumicino

Thu 4/16

6:30 am-5:58 pm

2 stops18h 28m

Chicago Midway

Wed 4/29

10:41 am-7:35 am

1 stop13h 54m

$659

RomeChicago

FCO - ORD

FCOORD

Rome Fiumicino

Mon 4/27

6:30 am-2:30 pm

1 stop15h 00m

Chicago O'Hare Intl

Mon 5/4

5:04 pm-4:35 pm

2 stops16h 31m

$660

RomeChicago

FCO - ORD

FCOORD

Rome Fiumicino

Thu 9/3

12:15 pm-7:26 pm

1 stop14h 11m

Chicago O'Hare Intl

Tue 9/22

1:15 pm-3:10 pm

2 stops18h 55m

$668

RomeChicago

FCO - ORD

FCOORD

Rome Fiumicino

Thu 4/23

6:30 am-4:18 pm

2 stops16h 48m

Chicago O'Hare Intl

Thu 4/30

7:10 am-7:35 am

1 stop17h 25m

$670

RomeChicago

FCO - MDW

FCOMDW

Rome Fiumicino

Mon 4/27

6:30 am-6:36 pm

2 stops19h 06m

Chicago Midway

Tue 5/5

7:16 pm-4:25 pm

2 stops14h 09m

$672

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/25

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Rome to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Rome with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rome to Indiana
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Rome to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Rome to Indiana?

    A quick flight from Rome to Indiana can take about 10h 30m. Icelandair provides one of the quickest options available for as low as $658. The distance from Rome to Indiana is about 4808 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Rome to Indiana?

    While some choose either Rome Ciampino - Chicago O'Hare Intl or Rome Fiumicino - Chicago Midway, Rome Fiumicino - Chicago O'Hare Intl is the most popular route from Rome to Indiana.

  • Can I find deals for flights from Rome to Indiana that include hotel bookings?

    Yes. In addition to deals on Rome to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rome to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rome to Indiana.

  • Can I find deals for business class flights from Rome to Indiana?

    Yes. Cheapflights offers flight deals from Rome to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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