HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Indiana

$52+ Cheap flights from Mesa, AZ to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — IND
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mesa to Indiana with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Mesa to Indiana

Keep the following information in mind while searching for Mesa to Indiana flight deals. Data was last updated September 15, 2025.

Round-trip from

$137
(Cheapflightsfares)

One-way from

$52
(Kiwi.com)

Popular in

July

Cheapest in

September

Average price

$319
From Mesa to Indiana
Search Deals
One-way flight from Mesa to Indiana
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($12 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Mesa to Indiana

Cheapest flights from Mesa to Indiana
Explore the most affordable flight options available from Mesa to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/233:30 pmPHX - ORD
Nonstop3h 40mFrontier
Mon 10/271:53 pmORD - PHX
Nonstop3h 56mFrontier
Deal found 9/15$137
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1610:39 amPHX - MDW
Nonstop3h 26mFrontier
Mon 10/2010:56 pmMDW - PHX
Nonstop3h 51mFrontier
Deal found 9/14$137
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:06 pmPHX - ORD
Nonstop3h 34mFrontier
Wed 10/87:15 amORD - PHX
1 stop9h 49mFrontier
Deal found 9/13$138
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/24:35 pmPHX - MDW
Nonstop3h 23mFrontier
Fri 10/34:48 pmMDW - PHX
1 stop8h 06mFrontier
Deal found 9/14$138
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/135:35 amPHX - ORD
1 stop6h 48mFrontier
Sun 11/163:30 pmORD - PHX
Nonstop4h 04mFrontier
Deal found 9/14$139
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/68:08 pmPHX - ORD
Nonstop3h 35mFrontier
Sun 11/93:30 pmORD - PHX
Nonstop4h 04mFrontier
Deal found 9/13$140
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3010:43 pmPHX - MDW
1 stop10h 47mFrontier
Mon 11/38:30 amMDW - PHX
Nonstop3h 53mFrontier
Deal found 9/14$140
This Frontier deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/137:25 amPHX - ORD
Nonstop3h 33mFrontier
Mon 10/206:50 amORD - PHX
1 stop6h 02mFrontier
Deal found 9/13$141
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/134:20 pmPHX - MDW
Nonstop3h 26mFrontier
Mon 10/2010:56 pmMDW - PHX
Nonstop3h 51mFrontier
Deal found 9/13$141
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/163:30 pmPHX - ORD
Nonstop3h 40mFrontier
Mon 10/206:23 pmORD - PHX
1 stop20h 54mFrontier
Deal found 9/14$142
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2312:02 pmPHX - MDW
1 stop10h 34mFrontier
Sun 10/267:50 amMDW - PHX
Nonstop3h 50mFrontier
Deal found 9/14$143
This Gotogate deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:45 pmPHX - ORD
Nonstop3h 30mFrontier
Thu 11/61:36 pmORD - PHX
1 stop10h 27mFrontier
Deal found 9/15$144

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Mesa to Indiana that are best for you.

Fly from

Mesa

Fly to

Indiana

Route

Depart

Return

Price

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

Fri 10/10

12:02 pm-4:29 pm

1 stop25h 27m

Indianapolis

Fri 10/17

8:51 pm-11:14 am

1 stop17h 23m

$164

PhoenixChicago

PHX - MDW

PHXMDW

Phoenix Sky Harbor Intl

Fri 11/14

5:20 am-9:35 am

Nonstop3h 15m

Chicago Midway

Tue 11/18

10:05 am-1:05 pm

Nonstop4h 00m

$165

PhoenixCincinnati

PHX - CVG

PHXCVG

Phoenix Sky Harbor Intl

Wed 9/24

8:00 am-10:41 pm

1 stop11h 41m

Cincinnati Cinci./N. Kentucky

Thu 9/25

4:48 pm-10:42 pm

1 stop8h 54m

$179

PhoenixCincinnati

PHX - CVG

PHXCVG

Phoenix Sky Harbor Intl

Fri 10/31

7:25 am-1:39 am

2 stops15h 14m

Cincinnati Cinci./N. Kentucky

Mon 11/3

3:22 pm-7:33 pm

1 stop6h 11m

$193

PhoenixChicago

PHX - MDW

PHXMDW

Phoenix Sky Harbor Intl

Fri 10/24

6:55 pm-12:10 am

Nonstop3h 15m

Chicago Midway

Fri 10/31

12:50 pm-2:35 pm

Nonstop3h 45m

$196

PhoenixChicago

PHX - MDW

PHXMDW

Phoenix Sky Harbor Intl

Wed 10/29

6:50 pm-12:05 am

Nonstop3h 15m

Chicago Midway

Sat 12/13

5:15 am-8:05 am

Nonstop3h 50m

$199

PhoenixCincinnati

PHX - CVG

PHXCVG

Phoenix Sky Harbor Intl

Thu 9/25

6:00 am-3:43 pm

1 stop6h 43m

Cincinnati Cinci./N. Kentucky

Mon 9/29

1:14 pm-5:13 pm

1 stop6h 59m

$199

PhoenixCincinnati

PHX - CVG

PHXCVG

Phoenix Sky Harbor Intl

Sat 10/11

1:10 pm-5:54 pm

1 stop25h 44m

Cincinnati Cinci./N. Kentucky

Sun 10/12

9:10 pm-11:41 pm

1 stop29h 31m

$200

PhoenixIndianapolis

PHX - IND

PHXIND

Phoenix Sky Harbor Intl

Sat 11/1

6:11 pm-9:44 am

2 stops12h 33m

Indianapolis

Sat 11/8

4:20 pm-9:58 pm

1 stop7h 38m

$201

PhoenixCincinnati

PHX - CVG

PHXCVG

Phoenix Sky Harbor Intl

Thu 10/23

10:19 am-4:57 pm

Nonstop3h 38m

Cincinnati Cinci./N. Kentucky

Tue 10/28

6:05 am-12:15 pm

1 stop9h 10m

$203

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Mesa to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to Indiana

What is the cheapest month to book a flight from Mesa to Indiana?

Currently, August is the cheapest month in which you can book a flight from Mesa to Indiana (average of $286). Flying from Mesa to Indiana in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to IN?

Find hourly flight availability from Mesa to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

When flying from Mesa to Indiana, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated September 15, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Mesa to Indiana to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,954 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,929 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,172 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Mesa to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mesa to Indiana?

    Departing from Mesa to Indiana will take you 3h 15m. There are 1440 mi between Mesa and Indiana. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Mesa to Indiana one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $53. United Airlines flights start at $92 while deals on Southwest start at $94 one-way.

  • What are the most popular routes from Mesa to Indiana?

    The most popular route from Mesa to Indiana is Phoenix Sky Harbor Intl - Chicago O'Hare Intl. You may also consider Phoenix Sky Harbor Intl - Chicago Midway or Phoenix Sky Harbor Intl - Indianapolis.

  • What are the most reliable airlines from Mesa to Indiana?

    Consider Southwest (81%), American Airlines (48%) or Alaska Airlines (48%) when booking your flight. These represent the most reliable airlines when flying from Mesa to Indiana.

  • What are the cheapest flights from Mesa to Indiana?

    While on average a flight from Mesa to Indiana is generally $387, our data shows the cheapest flight currently is $138. When looking at the most popular route, (Phoenix Sky Harbor Intl - Chicago O'Hare Intl), you can expect to pay $147 for that flight.

  • Can I find deals for flights from Mesa to Indiana that include hotel bookings?

    Yes. In addition to deals on Mesa to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Indiana.

  • Can I find deals for business class flights from Mesa to Indiana?

    Yes. Cheapflights offers flight deals from Mesa to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to Indiana?

    Currently, August is the cheapest month in which you can book a flight from Mesa to Indiana (average of $286). Flying from Mesa to Indiana in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mesa to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
Sky Harbor Intl to John F Kennedy Intl flights
Sky Harbor Intl to Seattle flights
Sky Harbor Intl to Newark flights
Sky Harbor Intl to Dallas/Fort Worth flights
Sky Harbor Intl to O'Hare Intl flights
Sky Harbor Intl to Boston flights
Sky Harbor Intl to Denver flights
Sky Harbor Intl to Las Vegas flights
Sky Harbor Intl to LaGuardia flights
Sky Harbor Intl to Orlando flights
Sky Harbor Intl to Honolulu flights
Sky Harbor Intl to San Francisco flights
Sky Harbor Intl to Los Angeles flights
Sky Harbor Intl to Atlanta flights
Las Vegas to Honolulu flights
Sky Harbor Intl to Portland flights
Las Vegas to Newark flights
Sky Harbor Intl to Minneapolis flights
Las Vegas to John F Kennedy Intl flights
Sky Harbor Intl to Salt Lake City flights
Sky Harbor Intl to Dulles Intl flights
Sky Harbor Intl to Miami flights
Las Vegas to Seattle flights
Las Vegas to Los Angeles flights
Sky Harbor Intl to Hobby flights
Sky Harbor Intl to Nashville flights
Sky Harbor Intl to Midway flights
Las Vegas to Orlando flights
Las Vegas to O'Hare Intl flights
Sky Harbor Intl to Reagan-National flights
Sky Harbor Intl to Baltimore flights
Sky Harbor Intl to Fort Lauderdale flights
Sky Harbor Intl to Santa Ana flights
Las Vegas to LaGuardia flights
Sky Harbor Intl to George Bush Intcntl flights
Sky Harbor Intl to San Diego flights
Sky Harbor Intl to Everett flights
Las Vegas to Santa Ana flights
Las Vegas to Fort Lauderdale flights
Sky Harbor Intl to Tampa flights
Sky Harbor Intl to Detroit flights
Tucson to Las Vegas flights
Sky Harbor Intl to Kahului flights
Las Vegas to Dallas/Fort Worth flights
Sky Harbor Intl to New Orleans flights
Las Vegas to Atlanta flights
Las Vegas to Kahului flights
Las Vegas to Sky Harbor Intl flights
Las Vegas to Miami flights
Las Vegas to Burbank flights

Top 7 airlines flying from Mesa to Indiana

Discover the top 7 airlines that operate flights from Mesa to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$100Average$222FlexibilityNo cancel feeOn-time65%
Allegiant AirCheapest$126Average$210FlexibilityNo cancel feeOn-time88%
FrontierCheapest$128Average$240FlexibilityNo cancel feeOn-time62%
DeltaCheapest$204Average$352FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$250Average$478FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$285Average$517FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$331Average$471FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.