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$66+ Cheap flights from Panama City, FL (ECP) to Illinois

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — ORD
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Panama City to Illinois

Keep the following information in mind while searching for Panama City to Illinois flight deals. Data was last updated September 15, 2025.

Round-trip from

$159
(American Airlines)

One-way from

$66
(United Airlines)

Popular in

September

Cheapest in

February

Average price

$417

Good round-trip deal

$319 or less

Good one-way deal

$189 or less
From Panama City NW Florida Beaches to Illinois
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One-way flight from Panama City NW Florida Beaches to Illinois
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Highest demand for flights based on searches. 15% potential increase in price ($59 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Panama City NW Florida Beaches to Illinois.
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Price to beat on a one-way flight from Panama City NW Florida Beaches to Illinois.
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Find flight deals from Panama City to Illinois

Cheapest flights from Panama City to Illinois
Explore the most affordable flight options available from Panama City to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/81:21 pmECP - ORD
1 stop6h 08mAmerican Airlines
Tue 11/116:46 amORD - ECP
1 stop4h 43mAmerican Airlines
Deal found 9/14$159
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/151:21 pmECP - ORD
1 stop8h 02mAmerican Airlines
Mon 11/173:50 pmORD - ECP
2 stops7h 25mAmerican Airlines
Deal found 9/13$164
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1512:05 pmECP - MDW
2 stops8h 30mSouthwest
Mon 11/178:15 amMDW - ECP
1 stop7h 35mSouthwest
Deal found 9/13$172
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:02 amECP - STL
1 stop5h 58mDelta
Sun 12/77:02 pmSTL - ECP
1 stop3h 56mDelta
Deal found 9/15$177
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/249:25 amECP - MDW
1 stop8h 20mSouthwest
Sun 10/2610:35 amMDW - ECP
1 stop7h 05mSouthwest
Deal found 9/14$183
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2411:05 amECP - ORD
1 stop10h 25mSouthwest
Mon 10/272:50 pmORD - ECP
1 stop7h 45mSouthwest
Deal found 9/13$194
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:17 pmECP - ORD
1 stop5h 41mDelta
Sun 10/266:45 amORD - ECP
1 stop5h 45mDelta
Deal found 9/15$197
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/162:00 pmECP - STL
Nonstop1h 50mSouthwest
Sun 10/197:00 amSTL - ECP
1 stop4h 40mSouthwest
Deal found 9/14$197
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:00 amECP - MDW
1 stop3h 51mDelta
Tue 10/2810:35 amMDW - ECP
1 stop4h 45mDelta
Deal found 9/14$197
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/182:10 pmECP - ORD
Nonstop2h 44mUnited Airlines
Fri 1/210:45 amORD - ECP
Nonstop2h 42mUnited Airlines
Deal found 9/13$201
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/171:55 pmECP - ORD
Nonstop2h 40mUnited Airlines
Mon 10/2010:40 amORD - ECP
Nonstop2h 30mUnited Airlines
Deal found 9/13$207
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/177:20 pmECP - STL
1 stop3h 35mSouthwest
Sun 10/197:00 amSTL - ECP
1 stop4h 40mSouthwest
Deal found 9/14$207

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Panama City to Illinois that are best for you.

Fly from

Panama City

Fly to

Illinois

Route

Depart

Return

Price

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Sat 11/15

12:05 pm-8:35 pm

2 stops8h 30m

Chicago Midway

Mon 11/17

8:15 am-3:50 pm

1 stop7h 35m

$172

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Fri 12/5

7:02 am-1:00 pm

1 stop5h 58m

Lambert-St Louis

Sun 12/7

7:02 pm-10:58 pm

1 stop3h 56m

$177

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Thu 10/23

7:20 pm-11:15 pm

1 stop3h 55m

Chicago Midway

Sun 10/26

10:35 am-5:40 pm

1 stop7h 05m

$183

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Fri 10/24

7:20 pm-11:15 pm

1 stop3h 55m

Chicago Midway

Mon 10/27

7:50 am-1:20 pm

1 stop5h 30m

$183

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Fri 10/24

9:25 am-5:45 pm

1 stop8h 20m

Chicago Midway

Sun 10/26

10:35 am-5:40 pm

1 stop7h 05m

$183

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Sat 11/8

6:00 am-10:13 am

1 stop4h 13m

Chicago O'Hare Intl

Mon 11/10

5:50 pm-10:57 pm

1 stop5h 07m

$197

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Thu 10/23

6:17 pm-11:58 pm

1 stop5h 41m

Chicago O'Hare Intl

Sun 10/26

6:45 am-12:30 pm

1 stop5h 45m

$197

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Mon 11/10

6:40 pm-12:01 am

1 stop5h 21m

Chicago O'Hare Intl

Mon 11/17

11:14 am-5:55 pm

1 stop6h 41m

$197

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Tue 12/23

6:59 pm-11:58 pm

1 stop4h 59m

Chicago O'Hare Intl

Fri 1/2

5:40 am-10:15 am

1 stop4h 35m

$197

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Thu 10/16

2:00 pm-3:50 pm

Nonstop1h 50m

Lambert-St Louis

Sun 10/19

7:00 am-11:40 am

1 stop4h 40m

$197

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 59 results
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Best time to book a flight from Panama City to Illinois

Have a flexible travel schedule? Discover the best time to fly to Illinois from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Illinois

What is the cheapest month to book a flight from Panama City, Florida to Illinois?

Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Illinois (average of $245). Flying from Panama City, Florida to Illinois in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to IL?

Find hourly flight availability from Panama City to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City, Florida to Illinois as you normally would.

Weekly flight availability from Panama City, Florida to Illinois

Explore weekly flight availability from Panama City to Illinois. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 15, 2025.

The most flights from ECP to USIL are scheduled on a Monday (1 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

Reviews of airlines servicing Illinois

Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated September 15, 2025.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Panama City to Illinois. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
Delta
8.0
Very good
7,954 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
United Airlines
7.4
Good
8,929 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Illinois?

    Located just 16.0 mi from the city center, Panama City NW Florida Beaches (ECP) is the airport most travelers will use when flying to Illinois from Panama City.

  • How long is the flight from Panama City, Florida to Illinois?

    Southwest and Delta can get you from Panama City, Florida to Illinois in just under 5h 58m. Your travel time can differ by up to 2h 32m. The distance between Panama City, Florida and Illinois is about 635 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Panama City, Florida to Illinois one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $66. However, be on the lookout for offers from Southwest and American Airlines, as they are both options that can get you from Panama City, Florida to Illinois for a low price.

  • What are the most popular routes from Panama City, Florida to Illinois?

    Most travelers choose Panama City NW Florida Beaches - Chicago O'Hare Intl, Panama City NW Florida Beaches - Chicago Midway or Panama City NW Florida Beaches - Lambert-St Louis when deciding on the best route from Panama City, Florida to Illinois.

  • What are the most reliable airlines from Panama City, Florida to Illinois?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Panama City, Florida to Illinois on time: Qatar Airways (100%), American Airlines (80%), Republic Airways (79%).

  • What are the cheapest flights from Panama City, Florida to Illinois?

    The cheapest flight price from Panama City, Florida to Illinois is $131. On average you can expect to pay $1,518. The most popular route, (Panama City NW Florida Beaches - Chicago O'Hare Intl), can usually be booked for $197.

  • Can I find deals for flights from Panama City to Illinois that include hotel bookings?

    Yes. In addition to deals on Panama City to Illinois flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Illinois?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Illinois.

  • Can I find deals for business class flights from Panama City to Illinois?

    Yes. Cheapflights offers flight deals from Panama City to Illinois by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Illinois?

    Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Illinois (average of $245). Flying from Panama City, Florida to Illinois in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to Illinois

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Panama City to Illinois

Discover the top 4 airlines that operate flights from Panama City to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$286FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$226Average$373FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$228Average$330FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$228Average$383FlexibilityNo cancel feeOn-time71%

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