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$56+ Cheap flights from Knoxville (TYS) to Illinois

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/21. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — ORD
Nov 26 — Dec 31
Wed 11/26
Wed 12/3
1 adult, Economy
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Find flight deals from Knoxville to Illinois

Cheapest flights from Knoxville to Illinois
Explore the most affordable flight options available from Knoxville to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

This Frontier deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/44:52 pmTYS - STL
1 stop18h 22mFrontier
Sat 12/137:43 pmSTL - TYS
1 stop19h 14mFrontier
Deal found 10/25$152
This Booking.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/44:52 pmTYS - STL
1 stop18h 22mFrontier
Sat 12/67:43 pmSTL - TYS
1 stop19h 14mFrontier
Deal found 10/25$162
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/121:14 pmTYS - ORD
Nonstop2h 03mAmerican Airlines
Sun 12/146:48 pmORD - TYS
Nonstop1h 52mAmerican Airlines
Deal found 10/26$189
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/142:02 pmTYS - MDW
Nonstop1h 35mMultiple Airlines
Mon 11/175:56 pmMDW - TYS
3 stops42h 01mMultiple Airlines
Deal found 10/26$193
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:45 amTYS - ORD
Nonstop2h 01mUnited Airlines
Sun 11/162:17 pmORD - TYS
Nonstop1h 51mUnited Airlines
Deal found 10/26$194
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:45 amTYS - ORD
Nonstop2h 01mUnited Airlines
Sun 11/97:20 amORD - TYS
Nonstop1h 45mUnited Airlines
Deal found 10/25$199
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2112:45 pmTYS - MDW
Nonstop1h 36mMultiple Airlines
Sun 11/305:30 pmMDW - TYS
1 stop21h 19mMultiple Airlines
Deal found 10/25$206
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/79:09 pmTYS - MDW
2 stops22h 30mMultiple Airlines
Mon 11/104:12 pmMDW - TYS
Nonstop1h 25mMultiple Airlines
Deal found 10/25$208
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:40 amTYS - MDW
1 stop5h 14mDelta
Sun 12/145:13 pmMDW - TYS
1 stop5h 15mDelta
Deal found 10/27$209
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:59 pmTYS - ORD
1 stop5h 02mDelta
Mon 12/155:42 pmORD - TYS
1 stop4h 36mDelta
Deal found 10/25$209
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/71:32 pmTYS - MDW
Nonstop1h 35mAllegiant Air
Fri 11/145:35 pmMDW - TYS
2 stops22h 47mAllegiant Air
Deal found 10/24$213
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/148:07 pmTYS - MDW
1 stop4h 33mDelta
Mon 11/1712:47 pmMDW - TYS
1 stop5h 15mDelta
Deal found 10/26$214

Cheap flight deals from Knoxville to Illinois

Keep the following information in mind while searching for Knoxville to Illinois flight deals. Data was last updated October 27, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$152
(Frontier)

One-way from

$56
(Kiwi.com)

Popular in

July

Cheapest in

February

Average price

$249

Good round-trip deal

$96 or less

Good one-way deal

$97 or less
Provider with most accurate pricing for Knoxville McGhee Tyson-Chicago (CHI) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Chicago (CHI) flights.
Search Deals
From Knoxville McGhee Tyson to Illinois
Search Deals
One-way flight from Knoxville McGhee Tyson to Illinois
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($18 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals
Price to beat on a round-trip flight from Knoxville McGhee Tyson to Illinois.
Search Deals
Price to beat on a one-way flight from Knoxville McGhee Tyson to Illinois.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from Knoxville to Illinois that are best for you.

Fly from

Knoxville

Fly to

Illinois

Route

Depart

Return

Price

KnoxvilleSt. Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Thu 12/4

4:52 pm-10:14 am

1 stop18h 22m

Lambert-St Louis

Sat 12/13

7:43 pm-3:57 pm

1 stop19h 14m

$152

KnoxvilleSt. Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Thu 12/4

4:52 pm-10:14 am

1 stop18h 22m

Lambert-St Louis

Sat 12/6

7:43 pm-3:57 pm

1 stop19h 14m

$162

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 11/20

8:26 am-9:30 am

Nonstop2h 04m

Chicago O'Hare Intl

Mon 11/24

8:04 pm-10:55 pm

Nonstop1h 51m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 12/12

6:29 pm-7:33 pm

Nonstop2h 04m

Chicago O'Hare Intl

Sun 12/14

11:42 am-2:27 pm

Nonstop1h 45m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 11/20

8:26 am-9:30 am

Nonstop2h 04m

Chicago O'Hare Intl

Sat 11/22

8:04 pm-10:55 pm

Nonstop1h 51m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 11/26

5:52 pm-6:53 pm

Nonstop2h 01m

Chicago O'Hare Intl

Wed 12/3

7:30 am-10:13 am

Nonstop1h 43m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 11/14

6:16 pm-7:20 pm

Nonstop2h 04m

Chicago O'Hare Intl

Mon 11/17

11:43 am-2:29 pm

Nonstop1h 46m

$194

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 11/14

8:26 am-9:30 am

Nonstop2h 04m

Chicago O'Hare Intl

Mon 11/17

7:20 am-10:05 am

Nonstop1h 45m

$194

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 11/13

6:45 am-7:38 am

Nonstop1h 53m

Chicago O'Hare Intl

Sun 11/16

2:17 pm-5:08 pm

Nonstop1h 51m

$194

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Sat 11/15

8:26 am-9:30 am

Nonstop2h 04m

Chicago O'Hare Intl

Wed 11/19

7:20 am-10:05 am

Nonstop1h 45m

$194

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 60 results
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Best time to book a flight from Knoxville to Illinois

Have a flexible travel schedule? Discover the best time to fly to Illinois from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Illinois

What is the cheapest month to book a flight from Knoxville to Illinois?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Illinois (average of $58). Flying from Knoxville to Illinois in February is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to IL?

Find hourly flight availability from Knoxville to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 27, 2025.

It’s typically best to fly out from Knoxville to Illinois at noon. Doing so could potentially save you 51% on the flight price compared to flying in the evening, which is usually more expensive.

What is the cheapest day to fly from Knoxville to Illinois?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Illinois. Price data was last updated on October 26, 2025.

Travelers seeking maximum savings on their Knoxville to Illinois flight should consider departing on Wednesday at noon when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Knoxville to Illinois

Explore weekly flight availability from Knoxville to Illinois. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated October 27, 2025.

The most flights from TYS to USIL are scheduled on a Sunday (32 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (17 on average).

Reviews of airlines servicing Illinois

Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated October 27, 2025.
Read through reviews of airlines operating flights from Knoxville to Illinois, such as Delta, United Airlines, and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,997 reviews

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,997 reviews
Delta
7.9
Good
7,997 reviews

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,999 reviews
Delta
7.9
Good
7,997 reviews

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,030 reviews
Delta
7.9
Good
7,997 reviews

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Allegiant Air
7.2
Good
695 reviews
Delta
7.9
Good
7,997 reviews

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Illinois?

    If you book a flight to Illinois from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • How long is the flight from Knoxville to Illinois?

    For as low as $189, Frontier can have you in Illinois from Knoxville in 2h 04m. The distance between Knoxville and Illinois is about 475 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Knoxville to Illinois one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $56. However, be on the lookout for offers from Frontier and American Airlines, as they are both options that can get you from Knoxville to Illinois for a low price.

  • What are the most popular routes from Knoxville to Illinois?

    When deciding which route to take from Knoxville to Illinois consider Knoxville McGhee Tyson - Chicago O'Hare Intl, Knoxville McGhee Tyson - Chicago Midway or Knoxville McGhee Tyson - Lambert-St Louis as they are the most popular.

  • What are the most reliable airlines from Knoxville to Illinois?

    No one likes to see their flight delayed. When booking a flight from Knoxville to Illinois consider choosing Republic Airways (96%), Avianca (92%) or GoJet (91%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Knoxville to Illinois?

    Looking for the cheapest flight from Knoxville to Illinois? While on average our users pay $959, our data indicates the cheapest price to be $146. The most popular route (Knoxville McGhee Tyson - Chicago O'Hare Intl), is priced around $189.

  • Can I find deals for flights from Knoxville to Illinois that include hotel bookings?

    Yes. In addition to deals on Knoxville to Illinois flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Illinois?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Illinois.

  • Can I find deals for business class flights from Knoxville to Illinois?

    Yes. Cheapflights offers flight deals from Knoxville to Illinois by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Illinois?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Illinois (average of $58). Flying from Knoxville to Illinois in February is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 4 airlines flying from Knoxville to Illinois

Discover the top 4 airlines that operate flights from Knoxville to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$60Average$99FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$189Average$377FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$193Average$338FlexibilityNo cancel feeOn-time69%
DeltaCheapest$233Average$323FlexibilityNo cancel feeOn-timeN/A

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