Illinois

$54+ Cheap flights from Knoxville (TYS) to Illinois

TYS — ORD
Dec 12 — Dec 191
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Cheap flight deals from Knoxville to Illinois

Cheapest flights from Knoxville to Illinois

Fri 12/41:58 pm -
2 stops25h 32m
Tue 1/194:47 pm -
1 stop16h 53m
Deal found 11/10$261
Thu 12/38:55 pm -
1 stop18h 05m
Mon 12/76:07 am -
1 stop30h 00m
Deal found 11/10$264
Wed 12/25:09 pm -
1 stop21h 51m
Mon 12/76:07 am -
1 stop30h 00m
Deal found 11/11$265
Wed 12/25:09 pm -
1 stop21h 51m
Sun 12/66:07 am -
1 stop25h 20m
Deal found 11/10$283
Fri 12/49:49 pm -
2 stops17h 41m
Mon 1/184:47 pm -
1 stop18h 23m
Deal found 11/10$289
Mon 12/71:58 pm -
1 stop7h 26m
Mon 1/184:47 pm -
1 stop18h 23m
Deal found 11/9$295
Sat 11/1410:55 am -
2 stops13h 52m
Mon 11/164:31 pm -
Nonstop1h 30m
Deal found 11/7$296
Mon 11/238:00 am -
Nonstop1h 39m
Sat 12/512:28 pm -
3 stops31h 03m
Deal found 11/9$303
Fri 12/41:58 pm -
1 stop7h 26m
Mon 12/76:07 am -
1 stop30h 00m
Deal found 11/11$304
Fri 11/201:01 pm -
Nonstop1h 39m
Mon 11/238:42 pm -
1 stop25h 41m
Deal found 11/7$311
Wed 12/92:40 pm -
1 stop6h 15m
Mon 1/186:50 am -
1 stop4h 05m
Deal found 11/8$312
Fri 11/131:17 pm -
2 stops29h 30m
Mon 11/164:31 pm -
Nonstop1h 30m
Deal found 11/7$316

Find flight deals from Knoxville to Illinois

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$246
(Kiwi.com)

One-way from

$54
(Super.com)

Popular in

September

Cheapest in

January

Average price

$359

Good round-trip deal

$85 or less

Good one-way deal

$70 or less
Provider with most accurate pricing for Knoxville McGhee Tyson-Chicago (CHI) flight deals.
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Chicago (CHI) flights.
From Knoxville McGhee Tyson to Illinois
One-way flight from Knoxville McGhee Tyson to Illinois
Highest demand for flights based on searches. 13% potential increase in price ($48 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
Average for round-trip flights in November 2026
Price to beat on a round-trip flight from Knoxville McGhee Tyson to Illinois.
Price to beat on a one-way flight from Knoxville McGhee Tyson to Illinois.

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Knoxville to Illinois that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

KnoxvilleChicago

TYS Knoxville McGhee Tyson - MDW Chicago Midway

TYSMDW

Knoxville McGhee Tyson

Fri 11/20

1:01 pm-1:40 pm

Nonstop1h 39m

Chicago Midway

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$63

KnoxvilleChicago

TYS Knoxville McGhee Tyson - MDW Chicago Midway

TYSMDW

Knoxville McGhee Tyson

Sat 12/12

2:50 pm-7:35 pm

1 stop5h 45m

Chicago Midway

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$154

KnoxvilleChicago

TYS Knoxville McGhee Tyson - MDW Chicago Midway

TYSMDW

Knoxville McGhee Tyson

Mon 12/7

5:15 pm-10:45 pm

1 stop6h 30m

Chicago Midway

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$164

KnoxvilleChicago

TYS Knoxville McGhee Tyson - MDW Chicago Midway

TYSMDW

Knoxville McGhee Tyson

Fri 12/4

2:40 pm-10:45 pm

2 stops9h 05m

Chicago Midway

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$194

KnoxvilleChicago

TYS Knoxville McGhee Tyson - MDW Chicago Midway

TYSMDW

Knoxville McGhee Tyson

Fri 11/20

7:25 pm-12:10 am

1 stop5h 45m

Chicago Midway

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$220

KnoxvilleChicago

TYS Knoxville McGhee Tyson - ORD Chicago O'Hare Intl

TYSORD

Knoxville McGhee Tyson

Sat 12/12

6:00 am-7:06 am

Nonstop2h 06m

Chicago O'Hare Intl

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$229

KnoxvilleChicago

TYS Knoxville McGhee Tyson - ORD Chicago O'Hare Intl

TYSORD

Knoxville McGhee Tyson

Mon 12/7

7:44 am-9:10 am

Nonstop2h 26m

Chicago O'Hare Intl

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$229

KnoxvilleChicago

TYS Knoxville McGhee Tyson - ORD Chicago O'Hare Intl

TYSORD

Knoxville McGhee Tyson

Sat 3/13

5:45 pm-6:46 pm

Nonstop2h 01m

Chicago O'Hare Intl

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$229

KnoxvilleChicago

TYS Knoxville McGhee Tyson - ORD Chicago O'Hare Intl

TYSORD

Knoxville McGhee Tyson

Mon 12/14

7:44 am-9:10 am

Nonstop2h 26m

Chicago O'Hare Intl

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$229

KnoxvilleChicago

TYS Knoxville McGhee Tyson - ORD Chicago O'Hare Intl

TYSORD

Knoxville McGhee Tyson

Mon 12/7

5:35 pm-6:36 pm

Nonstop2h 01m

Chicago O'Hare Intl

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$229

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/9

Showing 1-10 of 52 resultsSorted by cheapest first
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Best time to book a flight from Knoxville to Illinois

Have a flexible travel schedule? Discover the best time to fly to Illinois from Knoxville with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Illinois

What is the cheapest month to book a flight from Knoxville to Illinois?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Illinois (average of $267). Flying from Knoxville to Illinois in September is currently the most expensive (average of $390). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to IL?

It’s typically best to fly out from Knoxville to Illinois in the evening. Doing so could potentially save you 56% on the flight price compared to flying at noon, which is usually more expensive.

Weekly flight availability from Knoxville to Illinois

The most flights from TYS to USIL are scheduled on a Monday (33 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (19 on average).

How much does it cost to fly round-trip from Knoxville to Illinois?

Airfare is below average for this route at the moment.
Knoxville to Illinois flights typically cost between $307 and $415 in December.
The cheapest round-trip price found within the last 5 days was $246 on Multiple Airlines (Dec 2-Dec 7).

How far ahead should I book a flight from Knoxville to Illinois?

To ensure you get the cheapest price possible for a flight from Knoxville to Illinois, you should look to book at least 45 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest day to fly from Knoxville to Illinois?

Travelers seeking maximum savings on their Knoxville to Illinois flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Illinois

Read through reviews of airlines operating flights from Knoxville to Illinois, such as Southwest,United Airlines, andAllegiant Air. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
6.0
Good

Reza,Jun 2026

TPA - MDW

The seats were super cramped and couldn’t move without hitting other passengers

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
6.0
Good

Reza,Jun 2026

TPA - MDW

The seats were super cramped and couldn’t move without hitting other passengers

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
6.0
Good

Reza,Jun 2026

TPA - MDW

The seats were super cramped and couldn’t move without hitting other passengers

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
6.0
Good

Reza,Jun 2026

TPA - MDW

The seats were super cramped and couldn’t move without hitting other passengers

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
6.0
Good

Reza,Jun 2026

TPA - MDW

The seats were super cramped and couldn’t move without hitting other passengers

Related info for your journey

  • What airport do you fly from for flights from Knoxville to Illinois?

    If you book a flight to Illinois from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • How long is the flight from Knoxville to Illinois?

    For as low as $329, Southwest can have you in Illinois from Knoxville in 2h 06m. The distance between Knoxville and Illinois is about 475 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Knoxville to Illinois one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $49. However, be on the lookout for offers from Southwest and United Airlines, as they are both options that can get you from Knoxville to Illinois for a low price.

  • What are the most popular routes from Knoxville to Illinois?

  • What are the most reliable airlines from Knoxville to Illinois?

    No one likes to see their flight delayed. When booking a flight from Knoxville to Illinois consider choosing PSA Airlines (100%), Royal Jordanian (84%) or Japan Airlines (80%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Knoxville to Illinois?

    Looking for the cheapest flight from Knoxville to Illinois? While on average our users pay $1,113, our data indicates the cheapest price to be $159. The most popular route (Knoxville McGhee Tyson - Chicago O'Hare Intl), is priced around $261.

  • Can I find deals for flights from Knoxville to Illinois that include hotel bookings?

    Yes. In addition to deals on Knoxville to Illinois flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Illinois?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Illinois.

  • Can I find deals for business class flights from Knoxville to Illinois?

    Yes. Cheapflights offers flight deals from Knoxville to Illinois by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Illinois?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Illinois (average of $267). Flying from Knoxville to Illinois in September is currently the most expensive (average of $390). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Illinois

Top 3 airlines flying from Knoxville to Illinois

AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$78Average$141FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$189Average$335FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$207Average$360FlexibilityNo cancel feeOn-time71%

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