HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Illinois

$81+ Cheap flights from Knoxville (TYS) to Illinois

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — ORD
Jan 9 — Jan 161
Fri 1/9
Fri 1/16
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Illinois with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Illinois

Cheapest flights from Knoxville to Illinois
Explore the most affordable flight options available from Knoxville to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 10, 2025.

This United Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:45 amTYS - ORD
Nonstop2h 07mUnited Airlines
Fri 1/27:48 pmORD - TYS
Nonstop1h 51mUnited Airlines
Deal found 12/8$204
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:29 pmTYS - ORD
Nonstop2h 04mAmerican Airlines
Wed 1/710:07 amORD - TYS
Nonstop1h 39mAmerican Airlines
Deal found 12/9$234
This United Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:45 amTYS - ORD
Nonstop2h 07mUnited Airlines
Tue 12/307:48 pmORD - TYS
Nonstop1h 51mUnited Airlines
Deal found 12/8$238
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/231:24 pmTYS - ORD
1 stop5h 25mAmerican Airlines
Fri 1/211:41 amORD - TYS
Nonstop1h 50mAmerican Airlines
Deal found 12/8$244
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:48 amTYS - ORD
Nonstop2h 02mAmerican Airlines
Wed 12/318:00 amORD - TYS
1 stop7h 38mAmerican Airlines
Deal found 12/9$248
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:45 amTYS - ORD
Nonstop2h 07mUnited Airlines
Tue 1/1310:35 amORD - TYS
Nonstop1h 49mUnited Airlines
Deal found 12/9$249
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:45 amTYS - ORD
Nonstop2h 07mUnited Airlines
Tue 12/307:48 pmORD - TYS
Nonstop1h 51mUnited Airlines
Deal found 12/9$253
This Delta deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/177:39 amTYS - ORD
1 stop7h 11mDelta
Wed 1/79:55 amORD - TYS
1 stop4h 24mDelta
Deal found 12/9$254
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:58 pmTYS - ORD
Nonstop2h 10mAmerican Airlines
Sun 1/46:33 pmORD - TYS
Nonstop1h 48mAmerican Airlines
Deal found 12/8$257
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:42 amTYS - ORD
1 stop5h 21mAmerican Airlines
Wed 12/3111:41 amORD - TYS
Nonstop1h 47mAmerican Airlines
Deal found 12/8$258
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:00 amTYS - ORD
1 stop5h 21mAmerican Airlines
Tue 1/2010:07 amORD - TYS
Nonstop1h 39mAmerican Airlines
Deal found 12/9$259
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:08 pmTYS - ORD
Nonstop2h 12mAmerican Airlines
Mon 1/58:00 amORD - TYS
Nonstop1h 50mAmerican Airlines
Deal found 12/8$263

Find flight deals from Knoxville to Illinois

Keep the following information in mind while searching for Knoxville to Illinois flight deals. Data was last updated December 10, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$189
(United Airlines)

One-way from

$81
(Frontier)

Popular in

July

Cheapest in

February

Average price

$334

Good round-trip deal

$376 or less

Good one-way deal

$77 or less
Provider with most accurate pricing for Knoxville McGhee Tyson-Chicago (CHI) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Chicago (CHI) flights.
Search Deals
From Knoxville McGhee Tyson to Illinois
Search Deals
One-way flight from Knoxville McGhee Tyson to Illinois
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($13 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Knoxville McGhee Tyson to Illinois.
Search Deals
Price to beat on a one-way flight from Knoxville McGhee Tyson to Illinois.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 10, 2025.
Use the filters below to find and compare flights from Knoxville to Illinois that are best for you.

Fly from

Knoxville

Fly to

Illinois

Route

Depart

Return

Price

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 1/7

5:29 pm-6:27 pm

Nonstop1h 58m

Chicago O'Hare Intl

Wed 1/14

10:35 am-1:24 pm

Nonstop1h 49m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 2/26

4:56 pm-6:02 pm

Nonstop2h 06m

Chicago O'Hare Intl

Mon 3/2

6:40 pm-9:23 pm

Nonstop1h 43m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 3/4

10:55 am-12:02 pm

Nonstop2h 07m

Chicago O'Hare Intl

Mon 3/23

6:06 pm-8:47 pm

Nonstop1h 41m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 1/14

11:10 am-12:05 pm

Nonstop1h 55m

Chicago O'Hare Intl

Sat 1/17

7:42 am-10:32 am

Nonstop1h 50m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Mon 2/9

6:45 am-7:48 am

Nonstop2h 03m

Chicago O'Hare Intl

Mon 2/16

6:28 pm-9:10 pm

Nonstop1h 42m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 2/12

6:45 am-7:47 am

Nonstop2h 02m

Chicago O'Hare Intl

Sun 2/15

7:35 am-10:19 am

Nonstop1h 44m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Tue 12/23

6:45 am-7:52 am

Nonstop2h 07m

Chicago O'Hare Intl

Wed 12/31

7:25 am-10:17 am

Nonstop1h 52m

$204

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Tue 12/23

6:45 am-7:52 am

Nonstop2h 07m

Chicago O'Hare Intl

Fri 1/2

7:48 pm-10:39 pm

Nonstop1h 51m

$204

KnoxvilleSt. Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Thu 1/22

7:26 pm-6:51 am

2 stops36h 25m

Lambert-St Louis

Mon 1/26

10:16 am-5:28 pm

1 stop6h 12m

$206

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Fri 1/9

1:00 pm-5:37 pm

1 stop5h 37m

Chicago Midway

Tue 1/13

5:31 pm-11:45 pm

1 stop5h 14m

$209

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 55 results
1
2
3
...
6

Best time to book a flight from Knoxville to Illinois

Have a flexible travel schedule? Discover the best time to fly to Illinois from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Illinois

What is the cheapest month to book a flight from Knoxville to Illinois?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Illinois (average of $58). Flying from Knoxville to Illinois in February is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to IL?

Find hourly flight availability from Knoxville to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 10, 2025.

It’s typically best to fly out from Knoxville to Illinois at noon. Doing so could potentially save you 18% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Knoxville to Illinois?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Illinois. Price data was last updated on November 2, 2025.

Travelers seeking maximum savings on their Knoxville to Illinois flight should consider departing on Wednesday at noon when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Knoxville to Illinois

Explore weekly flight availability from Knoxville to Illinois. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 10, 2025.

The most flights from TYS to USIL are scheduled on a Monday (31 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (26 on average).

Reviews of airlines servicing Illinois

Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated December 10, 2025.
Read through reviews of airlines operating flights from Knoxville to Illinois, such as Delta, United Airlines, and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,092 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,048 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Allegiant Air
7.2
Good
699 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Illinois?

    If you book a flight to Illinois from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • How long is the flight from Knoxville to Illinois?

    For as low as $189, United Airlines can have you in Illinois from Knoxville in 1h 58m. The distance between Knoxville and Illinois is about 475 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Knoxville to Illinois one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $47. However, be on the lookout for offers from American Airlines and United Airlines, as they are both options that can get you from Knoxville to Illinois for a low price.

  • What are the most popular routes from Knoxville to Illinois?

    When deciding which route to take from Knoxville to Illinois consider Knoxville McGhee Tyson - Chicago O'Hare Intl, Knoxville McGhee Tyson - Chicago Midway or Knoxville McGhee Tyson - Greater Peoria as they are the most popular.

  • What are the most reliable airlines from Knoxville to Illinois?

    No one likes to see their flight delayed. When booking a flight from Knoxville to Illinois consider choosing Republic Airways (100%), Avianca (80%) or ANA (78%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Knoxville to Illinois?

    Looking for the cheapest flight from Knoxville to Illinois? While on average our users pay $916, our data indicates the cheapest price to be $128. The most popular route (Knoxville McGhee Tyson - Chicago O'Hare Intl), is priced around $189.

  • Can I find deals for flights from Knoxville to Illinois that include hotel bookings?

    Yes. In addition to deals on Knoxville to Illinois flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Illinois?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Illinois.

  • Can I find deals for business class flights from Knoxville to Illinois?

    Yes. Cheapflights offers flight deals from Knoxville to Illinois by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Illinois?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Illinois (average of $58). Flying from Knoxville to Illinois in February is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Illinois

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to LaGuardia flights
Nashville to John F Kennedy Intl flights
Nashville to Newark flights
Nashville to Los Angeles flights
Memphis to LaGuardia flights
Nashville to Orlando flights
Nashville to Miami flights
Nashville to Denver flights
Nashville to Seattle flights
Nashville to Fort Lauderdale flights
Nashville to Dallas/Fort Worth flights
Nashville to Las Vegas flights
Memphis to John F Kennedy Intl flights
Nashville to O'Hare Intl flights
Memphis to Las Vegas flights
Memphis to Atlanta flights
Nashville to Tampa flights
Memphis to Orlando flights
Nashville to Sky Harbor Intl flights
Chattanooga to LaGuardia flights
Nashville to Dulles Intl flights
Memphis to Los Angeles flights
Nashville to Hobby flights
Chattanooga to John F Kennedy Intl flights
Memphis to O'Hare Intl flights
Nashville to San Francisco flights
Nashville to Salt Lake City flights
Memphis to Newark flights
Knoxville to LaGuardia flights
Nashville to Baltimore flights
Nashville to Reagan-National flights
Nashville to Boston flights
Memphis to Dallas/Fort Worth flights
Memphis to Hobby flights
Nashville to Ontario flights
Memphis to Denver flights
Memphis to Miami flights
Nashville to George Bush Intcntl flights
Nashville to New Orleans flights
Chattanooga to Orlando flights
Knoxville to Denver flights
Knoxville to O'Hare Intl flights
Memphis to Sky Harbor Intl flights
Knoxville to Dallas/Fort Worth flights
Nashville to Santa Ana flights
Knoxville to Seattle flights
Nashville to Philadelphia flights
Knoxville to John F Kennedy Intl flights
Memphis to Tampa flights
Nashville to Honolulu flights

Top 4 airlines flying from Knoxville to Illinois

Discover the top 4 airlines that operate flights from Knoxville to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$60Average$103FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$189Average$347FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$189Average$278FlexibilityNo cancel feeOn-time71%
DeltaCheapest$258Average$373FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.