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$105+ Cheap flights from Knoxville (TYS) to Illinois

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — ORD
Feb 22 — Mar 11
Sun 2/22
Sun 3/1
1 adult, Economy
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Cheap flight deals from Knoxville to Illinois

Cheapest flights from Knoxville to Illinois
Explore the most affordable flight options available from Knoxville to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 23, 2026.

This United Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:45 am
TYS
-
ORD
Nonstop2h 02m
United Airlines
Thu 2/267:25 am
ORD
-
TYS
Nonstop1h 47m
United Airlines
Deal found 1/22$189
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1211:42 am
TYS
-
ORD
Nonstop1h 59m
American Airlines
Sun 2/158:02 am
ORD
-
TYS
Nonstop1h 43m
American Airlines
Deal found 1/21$190
This Kiwi.com deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/195:56 pm
TYS
-
ORD
2 stops41h 50m
Multiple Airlines
Thu 2/265:15 am
ORD
-
TYS
1 stop15h 52m
Multiple Airlines
Deal found 1/22$191
This American Airlines deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/107:54 am
TYS
-
ORD
Nonstop2h 08m
American Airlines
Tue 2/175:55 pm
ORD
-
TYS
Nonstop1h 45m
American Airlines
Deal found 1/23$204
This Delta deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/132:38 pm
TYS
-
MDW
1 stop4h 07m
Delta
Mon 2/161:26 pm
MDW
-
TYS
1 stop6h 29m
Delta
Deal found 1/22$209
This Delta deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/136:41 pm
TYS
-
ORD
1 stop6h 15m
Delta
Sun 2/155:25 am
ORD
-
TYS
1 stop4h 43m
Delta
Deal found 1/23$209
This Southwest deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1812:30 pm
TYS
-
MDW
1 stop7h 50m
Southwest
Tue 3/241:20 pm
MDW
-
TYS
2 stops6h 50m
Southwest
Deal found 1/22$214
This United Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/66:45 am
TYS
-
ORD
Nonstop2h 03m
United Airlines
Tue 2/106:10 pm
ORD
-
TYS
Nonstop1h 42m
United Airlines
Deal found 1/22$219
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/64:25 pm
TYS
-
ORD
2 stops25h 10m
Multiple Airlines
Sun 2/85:25 am
ORD
-
TYS
1 stop11h 28m
Multiple Airlines
Deal found 1/21$221
This Delta deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/107:30 am
TYS
-
MDW
1 stop6h 16m
Delta
Tue 2/176:40 pm
MDW
-
TYS
1 stop4h 12m
Delta
Deal found 1/23$224
This United Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:00 am
TYS
-
ORD
Nonstop2h 00m
United Airlines
Sun 3/87:35 am
ORD
-
TYS
Nonstop1h 44m
United Airlines
Deal found 1/22$224
This Southwest deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:50 pm
TYS
-
MDW
2 stops7h 55m
Southwest
Sat 5/96:10 am
MDW
-
TYS
2 stops11h 20m
Southwest
Deal found 1/23$225

Find flight deals from Knoxville to Illinois

Keep the following information in mind while searching for Knoxville to Illinois flight deals. Data was last updated January 23, 2026.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$189
(United Airlines)

One-way from

$105
(Southwest)

Popular in

July

Cheapest in

February

Average price

$230

Good round-trip deal

$341 or less

Good one-way deal

$237 or less
Provider with most accurate pricing for Knoxville McGhee Tyson-Chicago (CHI) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Chicago (CHI) flights.
Search Deals
From Knoxville McGhee Tyson to Illinois
Search Deals
One-way flight from Knoxville McGhee Tyson to Illinois
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Knoxville McGhee Tyson to Illinois.
Search Deals
Price to beat on a one-way flight from Knoxville McGhee Tyson to Illinois.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 23, 2026.
Use the filters below to find and compare flights from Knoxville to Illinois that are best for you.

Fly from

Knoxville

Fly to

Illinois

Route

Depart

Return

Price

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 2/19

4:02 pm-5:04 pm

Nonstop2h 02m

Chicago O'Hare Intl

Mon 2/23

8:02 am-10:45 am

Nonstop1h 43m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 2/19

6:45 am-7:47 am

Nonstop2h 02m

Chicago O'Hare Intl

Thu 2/26

7:25 am-10:12 am

Nonstop1h 47m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Sat 2/21

7:51 am-8:59 am

Nonstop2h 08m

Chicago O'Hare Intl

Sat 2/28

8:02 am-10:45 am

Nonstop1h 43m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Sat 2/21

1:50 pm-2:54 pm

Nonstop2h 04m

Chicago O'Hare Intl

Sat 2/28

7:35 am-10:19 am

Nonstop1h 44m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Sat 2/28

6:45 am-7:47 am

Nonstop2h 02m

Chicago O'Hare Intl

Sun 3/1

6:00 pm-8:37 pm

Nonstop1h 37m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 2/25

10:53 am-12:00 pm

Nonstop2h 07m

Chicago O'Hare Intl

Mon 3/2

7:25 am-10:12 am

Nonstop1h 47m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 4/3

7:00 am-7:55 am

Nonstop1h 55m

Chicago O'Hare Intl

Tue 4/7

7:15 am-10:08 am

Nonstop1h 53m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 2/25

10:53 am-12:00 pm

Nonstop2h 07m

Chicago O'Hare Intl

Sat 2/28

7:35 am-10:19 am

Nonstop1h 44m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Sat 2/14

6:45 am-7:47 am

Nonstop2h 02m

Chicago O'Hare Intl

Mon 2/16

6:00 pm-8:37 pm

Nonstop1h 37m

$189

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 2/27

6:45 am-7:47 am

Nonstop2h 02m

Chicago O'Hare Intl

Sun 3/1

6:00 pm-8:37 pm

Nonstop1h 37m

$189

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/23

Showing 1-10 of 58 results
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Best time to book a flight from Knoxville to Illinois

Have a flexible travel schedule? Discover the best time to fly to Illinois from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Illinois

What is the cheapest month to book a flight from Knoxville to Illinois?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Illinois (average of $58). Flying from Knoxville to Illinois in January is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to IL?

Find hourly flight availability from Knoxville to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 23, 2026.

It’s typically best to fly out from Knoxville to Illinois in the morning. Doing so could potentially save you 40% on the flight price compared to flying in the evening, which is usually more expensive.

What is the cheapest day to fly from Knoxville to Illinois?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Illinois. Price data was last updated on November 2, 2025.

Travelers seeking maximum savings on their Knoxville to Illinois flight should consider departing on Wednesday at noon when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Knoxville to Illinois

Explore weekly flight availability from Knoxville to Illinois. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 23, 2026.

The most flights from TYS to USIL are scheduled on a Thursday (24 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (15 on average).

Reviews of airlines servicing Illinois

Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated January 23, 2026.
Read through reviews of airlines operating flights from Knoxville to Illinois, such as Delta, United Airlines, and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,110 reviews

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,110 reviews
Delta
7.9
Good
8,110 reviews

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,193 reviews
Delta
7.9
Good
8,110 reviews

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,193 reviews
Delta
7.9
Good
8,110 reviews

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Allegiant Air
7.2
Good
705 reviews
Delta
7.9
Good
8,110 reviews

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Illinois?

    If you book a flight to Illinois from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • How long is the flight from Knoxville to Illinois?

    For as low as $189, American Airlines can have you in Illinois from Knoxville in 2h 02m. The distance between Knoxville and Illinois is about 475 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Knoxville to Illinois one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $47. However, be on the lookout for offers from American Airlines and United Airlines, as they are both options that can get you from Knoxville to Illinois for a low price.

  • What are the most popular routes from Knoxville to Illinois?

    When deciding which route to take from Knoxville to Illinois consider Knoxville McGhee Tyson - Chicago O'Hare Intl, Knoxville McGhee Tyson - Chicago Midway or Knoxville McGhee Tyson - Lambert-St Louis as they are the most popular.

  • What are the most reliable airlines from Knoxville to Illinois?

    No one likes to see their flight delayed. When booking a flight from Knoxville to Illinois consider choosing Republic Airways (79%), Envoy Air (75%) or ANA (73%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Knoxville to Illinois?

    Looking for the cheapest flight from Knoxville to Illinois? While on average our users pay $1,150, our data indicates the cheapest price to be $138. The most popular route (Knoxville McGhee Tyson - Chicago O'Hare Intl), is priced around $189.

  • Can I find deals for flights from Knoxville to Illinois that include hotel bookings?

    Yes. In addition to deals on Knoxville to Illinois flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Illinois?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Illinois.

  • Can I find deals for business class flights from Knoxville to Illinois?

    Yes. Cheapflights offers flight deals from Knoxville to Illinois by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Illinois?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Illinois (average of $58). Flying from Knoxville to Illinois in January is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 4 airlines flying from Knoxville to Illinois

Discover the top 4 airlines that operate flights from Knoxville to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$60Average$103FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$189Average$332FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$189Average$279FlexibilityNo cancel feeOn-time71%
DeltaCheapest$233Average$446FlexibilityNo cancel feeOn-timeN/A

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