$85+ Cheap flights from Des Moines (DSM) to Houston
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — HOU
Apr 7 — Apr 141
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Des Moines to Houston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to Houston are usually found in July or May, booked 37 days in advance, depart on a Wednesday or Monday and return on a Monday
Cheap flight deals from Des Moines to Houston
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to HoustonExplore the most affordable flight options available from Des Moines to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 8, 2026.
Explore the most affordable flight options available from Des Moines to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 8, 2026.
This Southwest deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:35 am
DSM
- HOU
1 stop7h 05m
Southwest
Sat 4/258:25 am
HOU
- DSM
2 stops9h 35m
Southwest
Deal found 3/4![Southwest logo]()
$254
This Delta deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:26 am
DSM
- IAH
2 stops10h 59m
Delta
Tue 5/195:55 am
IAH
- DSM
1 stop5h 13m
Delta
Deal found 3/3![Delta logo]()
$254
This Frontier deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:20 pm
DSM
- IAH
1 stop10h 28m
Frontier
Mon 5/186:45 am
IAH
- DSM
1 stop6h 44m
Frontier
Deal found 3/3![Frontier logo]()
$256
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/33:21 pm
DSM
- IAH
1 stop6h 00m
United Airlines
Fri 4/108:13 pm
IAH
- DSM
Nonstop2h 30m
United Airlines
Deal found 3/6![United Airlines logo]()
$258
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/205:25 am
DSM
- HOU
2 stops9h 10m
Southwest
Mon 4/274:25 pm
HOU
- DSM
2 stops6h 40m
Southwest
Deal found 3/6![Southwest logo]()
$259
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/247:15 am
DSM
- IAH
Nonstop2h 38m
United Airlines
Tue 3/316:15 am
IAH
- DSM
1 stop6h 14m
United Airlines
Deal found 3/4![United Airlines logo]()
$259
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:00 am
DSM
- IAH
1 stop5h 51m
United Airlines
Sat 7/116:10 am
IAH
- DSM
1 stop6h 20m
United Airlines
Deal found 3/5![United Airlines logo]()
$261
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/38:20 am
DSM
- IAH
Nonstop2h 36m
United Airlines
Sun 4/58:13 pm
IAH
- DSM
Nonstop2h 30m
United Airlines
Deal found 3/3![United Airlines logo]()
$264
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:04 pm
DSM
- IAH
Nonstop2h 36m
United Airlines
Thu 4/238:13 pm
IAH
- DSM
Nonstop2h 30m
United Airlines
Deal found 3/4![United Airlines logo]()
$265
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/277:15 am
DSM
- IAH
Nonstop2h 38m
United Airlines
Thu 4/26:15 am
IAH
- DSM
1 stop6h 14m
United Airlines
Deal found 3/3![United Airlines logo]()
$267
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:37 pm
DSM
- HOU
1 stop4h 21m
American Airlines
Sat 3/286:00 am
HOU
- DSM
1 stop4h 44m
American Airlines
Deal found 3/4![American Airlines logo]()
$269
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:37 pm
DSM
- IAH
1 stop4h 15m
American Airlines
Sat 3/286:00 am
IAH
- DSM
1 stop4h 44m
American Airlines
Deal found 3/4![American Airlines logo]()
$269
Best flights from Des Moines to HoustonDiscover carefully curated flight deals from Des Moines to Houston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 8, 2026.
Discover carefully curated flight deals from Des Moines to Houston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 8, 2026.
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:20 am
DSM
- IAH
Nonstop2h 29m
United Airlines
Mon 7/205:04 am
IAH
- DSM
1 stop5h 23m
United Airlines
Deal found 3/7![United Airlines logo]()
$258
This Southwest deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:35 am
DSM
- HOU
2 stops9h 20m
Southwest
Sat 4/255:35 am
HOU
- DSM
2 stops7h 55m
Southwest
Deal found 3/4![Southwest logo]()
$259
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:51 am
DSM
- IAH
2 stops10h 18m
Delta
Wed 4/85:25 am
IAH
- DSM
2 stops10h 17m
Delta
Deal found 3/4![Delta logo]()
$259
This Southwest deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:20 pm
DSM
- HOU
2 stops6h 50m
Southwest
Mon 4/204:25 pm
HOU
- DSM
2 stops6h 40m
Southwest
Deal found 3/4![Southwest logo]()
$259
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/296:59 pm
DSM
- IAH
1 stop5h 31m
United Airlines
Sat 4/48:13 pm
IAH
- DSM
Nonstop2h 30m
United Airlines
Deal found 3/4![United Airlines logo]()
$275
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/22:35 pm
DSM
- IAH
2 stops9h 22m
Delta
Tue 7/79:40 am
IAH
- DSM
2 stops11h 05m
Delta
Deal found 3/7![Delta logo]()
$284
This Southwest deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:30 am
DSM
- HOU
2 stops10h 00m
Southwest
Tue 4/287:00 am
HOU
- DSM
2 stops7h 05m
Southwest
Deal found 3/7![Southwest logo]()
$259
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:05 pm
DSM
- IAH
1 stop6h 54m
United Airlines
Mon 5/188:15 pm
IAH
- DSM
Nonstop2h 30m
United Airlines
Deal found 3/3![United Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:10 pm
DSM
- HOU
1 stop5h 15m
Southwest
Mon 4/135:10 am
HOU
- DSM
1 stop6h 35m
Southwest
Deal found 3/6![Southwest logo]()
$264
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/103:21 pm
DSM
- IAH
1 stop6h 00m
United Airlines
Sun 4/128:13 pm
IAH
- DSM
Nonstop2h 30m
United Airlines
Deal found 3/7![United Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:30 am
DSM
- HOU
2 stops7h 30m
Southwest
Fri 3/276:10 am
HOU
- DSM
1 stop7h 30m
Southwest
Deal found 3/7![Southwest logo]()
$274
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/43:21 pm
DSM
- IAH
1 stop6h 00m
United Airlines
Wed 4/88:13 pm
IAH
- DSM
Nonstop2h 30m
United Airlines
Deal found 3/3![United Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/101:45 pm
DSM
- HOU
1 stop8h 50m
Southwest
Sun 4/125:00 am
HOU
- DSM
1 stop6h 25m
Southwest
Deal found 3/3![Southwest logo]()
$303
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1111:25 am
DSM
- IAH
1 stop5h 46m
United Airlines
Tue 4/146:15 am
IAH
- DSM
1 stop6h 14m
United Airlines
Deal found 3/7![United Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:10 pm
DSM
- HOU
1 stop5h 15m
Southwest
Tue 5/191:20 pm
HOU
- DSM
1 stop7h 55m
Southwest
Deal found 3/3![Southwest logo]()
$311
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:20 am
DSM
- IAH
Nonstop2h 29m
United Airlines
Tue 5/268:12 pm
IAH
- DSM
Nonstop2h 23m
United Airlines
Deal found 3/5![United Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:25 am
DSM
- HOU
2 stops6h 50m
Southwest
Mon 4/204:25 pm
HOU
- DSM
2 stops6h 40m
Southwest
Deal found 3/6![Southwest logo]()
$314
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:20 am
DSM
- IAH
Nonstop2h 29m
United Airlines
Mon 6/85:04 am
IAH
- DSM
1 stop5h 23m
United Airlines
Deal found 3/6![United Airlines logo]()
$327
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/293:15 pm
DSM
- HOU
1 stop4h 40m
Southwest
Sun 5/33:05 pm
HOU
- DSM
2 stops7h 15m
Southwest
Deal found 3/3![Southwest logo]()
$334
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:16 pm
DSM
- IAH
1 stop5h 36m
United Airlines
Mon 4/208:13 pm
IAH
- DSM
Nonstop2h 30m
United Airlines
Deal found 3/6![United Airlines logo]()
$344
Last-minute flights from Des Moines to HoustonDiscover last-minute flight deals from Des Moines to Houston. Data last updated March 8, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Houston. Data last updated March 8, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:37 pm
DSM
- HOU
1 stop4h 21m
American Airlines
Sat 3/286:00 am
HOU
- DSM
1 stop4h 44m
American Airlines
Deal found 3/4![American Airlines logo]()
$269
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:37 pm
DSM
- IAH
1 stop4h 15m
American Airlines
Sat 3/286:00 am
IAH
- DSM
1 stop4h 44m
American Airlines
Deal found 3/4![American Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/247:15 am
DSM
- IAH
Nonstop2h 38m
United Airlines
Tue 3/316:15 am
IAH
- DSM
1 stop6h 14m
United Airlines
Deal found 3/4![United Airlines logo]()
$259
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:20 pm
DSM
- HOU
1 stop5h 22m
Delta
Tue 3/3111:33 am
HOU
- DSM
2 stops9h 12m
Delta
Deal found 3/4![Delta logo]()
$274
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:20 pm
DSM
- IAH
1 stop6h 39m
Delta
Tue 3/3111:35 am
IAH
- DSM
2 stops9h 10m
Delta
Deal found 3/4![Delta logo]()
$274
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/277:15 am
DSM
- IAH
Nonstop2h 38m
United Airlines
Thu 4/26:15 am
IAH
- DSM
1 stop6h 14m
United Airlines
Deal found 3/3![United Airlines logo]()
$267
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/33:21 pm
DSM
- IAH
1 stop6h 00m
United Airlines
Fri 4/108:13 pm
IAH
- DSM
Nonstop2h 30m
United Airlines
Deal found 3/6![United Airlines logo]()
$258
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/38:20 am
DSM
- IAH
Nonstop2h 36m
United Airlines
Sun 4/58:13 pm
IAH
- DSM
Nonstop2h 30m
United Airlines
Deal found 3/3![United Airlines logo]()
$264
This Delta deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/412:29 pm
DSM
- IAH
2 stops11h 30m
Delta
Tue 4/75:23 am
IAH
- DSM
1 stop5h 25m
Delta
Deal found 3/3![Delta logo]()
$254
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:04 pm
DSM
- IAH
Nonstop2h 36m
United Airlines
Thu 4/238:13 pm
IAH
- DSM
Nonstop2h 30m
United Airlines
Deal found 3/4![United Airlines logo]()
$265
This Southwest deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:35 am
DSM
- HOU
1 stop7h 05m
Southwest
Sat 4/258:25 am
HOU
- DSM
2 stops9h 35m
Southwest
Deal found 3/4![Southwest logo]()
$254
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/205:25 am
DSM
- HOU
2 stops9h 10m
Southwest
Mon 4/274:25 pm
HOU
- DSM
2 stops6h 40m
Southwest
Deal found 3/6![Southwest logo]()
$259
One-way flights from Des Moines to HoustonSearch for one-way flight options from Des Moines to Houston. Find affordable one-way fares based on user searches. Data last updated March 8, 2026.
Search for one-way flight options from Des Moines to Houston. Find affordable one-way fares based on user searches. Data last updated March 8, 2026.
This Super.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/258:21 pm
DSM
- IAH
1 stop12h 37m
Frontier
Deal found 3/6![Frontier logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/278:21 pm
DSM
- IAH
1 stop28h 18m
Frontier
Deal found 3/3![Frontier logo]()
$100
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:30 am
DSM
- HOU
1 stop7h 30m
Southwest
Deal found 3/5![Southwest logo]()
$105
This Southwest deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:15 pm
DSM
- HOU
1 stop4h 40m
Southwest
Deal found 3/7![Southwest logo]()
$120
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3112:15 pm
DSM
- HOU
1 stop9h 00m
Southwest
Deal found 3/8![Southwest logo]()
$125
This Expedia deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2210:55 am
DSM
- IAH
1 stop20h 34m
Frontier
Deal found 3/3![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:00 am
DSM
- IAH
2 stops26h 53m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$144
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:20 am
DSM
- IAH
Nonstop2h 36m
United Airlines
Deal found 3/4![United Airlines logo]()
$154
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/225:00 am
DSM
- HOU
1 stop4h 43m
American Airlines
Deal found 3/7![American Airlines logo]()
$164
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 am
DSM
- IAH
1 stop6h 43m
American Airlines
Deal found 3/3![American Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/242:04 pm
DSM
- IAH
2 stops27h 58m
Frontier
Deal found 3/7![Frontier logo]()
$169
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/171:55 pm
DSM
- HOU
1 stop9h 00m
Southwest
Deal found 3/5![Southwest logo]()
$180
Find flight deals from Des Moines to Houston
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Houston (HO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 8, 2026.
Round-trip from | $254 (Southwest) |
|---|---|
One-way from | $85 (Super.com) |
Popular in | December |
Cheapest in | July |
Average price | $308 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 8, 2026.
Use the filters below to find and compare flights from Des Moines to Houston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesHouston
DSM - IAH
DSMIAH
Des Moines
Fri 7/17
6:20 am-8:49 am
Nonstop2h 29m
Houston George Bush Intcntl
Mon 7/20
5:04 am-10:27 am
1 stop5h 23m
$258
Des MoinesHouston
DSM - HOU
DSMHOU
Des Moines
Sat 4/18
5:35 am-2:55 pm
2 stops9h 20m
Houston Hobby
Sat 4/25
5:35 am-1:30 pm
2 stops7h 55m
$259
Des MoinesHouston
DSM - IAH
DSMIAH
Des Moines
Wed 4/1
10:51 am-9:09 pm
2 stops10h 18m
Houston George Bush Intcntl
Wed 4/8
5:25 am-3:42 pm
2 stops10h 17m
$259
Des MoinesHouston
DSM - HOU
DSMHOU
Des Moines
Fri 4/17
4:20 pm-11:10 pm
2 stops6h 50m
Houston Hobby
Mon 4/20
4:25 pm-11:05 pm
2 stops6h 40m
$259
Des MoinesHouston
DSM - HOU
DSMHOU
Des Moines
Tue 4/21
5:30 am-3:30 pm
2 stops10h 00m
Houston Hobby
Tue 4/28
7:00 am-2:05 pm
2 stops7h 05m
$259
Des MoinesHouston
DSM - HOU
DSMHOU
Des Moines
Thu 4/9
7:10 pm-12:25 am
1 stop5h 15m
Houston Hobby
Mon 4/13
5:10 am-11:45 am
1 stop6h 35m
$264
Des MoinesHouston
DSM - HOU
DSMHOU
Des Moines
Tue 3/24
5:30 am-1:00 pm
2 stops7h 30m
Houston Hobby
Fri 3/27
6:10 am-1:40 pm
1 stop7h 30m
$274
Des MoinesHouston
DSM - IAH
DSMIAH
Des Moines
Sun 3/29
6:59 pm-12:30 am
1 stop5h 31m
Houston George Bush Intcntl
Sat 4/4
8:13 pm-10:43 pm
Nonstop2h 30m
$275
Des MoinesHouston
DSM - IAH
DSMIAH
Des Moines
Thu 7/2
2:35 pm-11:57 pm
2 stops9h 22m
Houston George Bush Intcntl
Tue 7/7
9:40 am-8:45 pm
2 stops11h 05m
$284
Des MoinesHouston
DSM - IAH
DSMIAH
Des Moines
Fri 5/15
7:05 pm-1:59 am
1 stop6h 54m
Houston George Bush Intcntl
Mon 5/18
8:15 pm-10:45 pm
Nonstop2h 30m
$289
Showing 1-10 of 39 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Houston
Have a flexible travel schedule? Discover the best time to fly to Houston from Des Moines with our price prediction graph.
DSM-HO1
DSM-HOU
DSM-IAH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Houston
DSM-HO1
DSM-HOU
DSM-IAH
How far ahead should I book a flight from Des Moines to Houston?
Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Houston. Price data was last updated on March 6, 2026.
To ensure you get the cheapest price possible for a flight from Des Moines to Houston, you should look to book at least 37 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Des Moines to Houston?
Currently, May is the cheapest month in which you can book a flight from Des Moines to Houston (average of $65). Flying from Des Moines to Houston in September is currently the most expensive (average of $228). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to HOU?
Find hourly flight availability from Des Moines to Houston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 8, 2026.
When flying from Des Moines to Houston, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Reviews of airlines servicing Houston
Get insights into the airlines that provide service to Houston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Houston. Reviews last updated March 8, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Des Moines to Houston to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Crew
8.6
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Crew
8.6
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Crew
8.6
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Crew
8.6
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Crew
8.6
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Houston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Des Moines
Popular flights
Alternative routes for Des Moines to Houston
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Houston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Houston by cabin class
Find flights from Des Moines to Houston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Houston flights
Browse other Des Moines and Houston flight options. Last updated on March 8, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on March 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 5 airlines flying from Des Moines to Houston
Discover the top 5 airlines that operate flights from Des Moines to Houston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$53 | Average$102 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$114 | Average$228 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$166 | Average$334 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$209 | Average$321 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$218 | Average$283 | FlexibilityNo cancel fee | On-time71% |