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Harrisburg

$53+ Cheap flights from South Carolina to Harrisburg (MDT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDT
Jun 4 — Jun 111
Thu 6/4
Thu 6/11
1 adult, Economy
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Cheap flight deals from South Carolina to Harrisburg

Cheapest flights from South Carolina to Harrisburg
Explore the most affordable flight options available from South Carolina to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:34 pm
MYR
-
MDT
Nonstop1h 34m
Allegiant Air
Sat 6/133:08 pm
MDT
-
MYR
Nonstop1h 36m
Allegiant Air
Deal found 5/5$105
This Cheapflightsfares deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:54 pm
MYR
-
MDT
Nonstop1h 36m
Allegiant Air
Sun 10/183:58 pm
MDT
-
MYR
Nonstop1h 30m
Allegiant Air
Deal found 5/5$129
This Cheapflightsfares deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:26 pm
MYR
-
MDT
Nonstop1h 34m
Allegiant Air
Sun 6/284:00 pm
MDT
-
MYR
Nonstop1h 36m
Allegiant Air
Deal found 5/2$133
This Cheapflightsfares deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:26 pm
MYR
-
MDT
Nonstop1h 34m
Allegiant Air
Sun 6/144:00 pm
MDT
-
MYR
Nonstop1h 36m
Allegiant Air
Deal found 5/1$134
This Cheapflightsfares deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/72:28 pm
MYR
-
MDT
Nonstop1h 38m
Allegiant Air
Sun 5/243:54 pm
MDT
-
MYR
Nonstop1h 31m
Allegiant Air
Deal found 5/1$139
This Cheapflightsfares deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:26 pm
MYR
-
MDT
Nonstop1h 34m
Allegiant Air
Thu 6/114:00 pm
MDT
-
MYR
Nonstop1h 36m
Allegiant Air
Deal found 5/1$144
This Cheapflightsfares deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/142:28 pm
MYR
-
MDT
Nonstop1h 38m
Allegiant Air
Sun 5/1712:10 pm
MDT
-
MYR
Nonstop1h 28m
Allegiant Air
Deal found 5/4$153
This Cheapflightsfares deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/34:52 pm
MYR
-
MDT
Nonstop1h 31m
Allegiant Air
Sun 9/132:38 pm
MDT
-
MYR
Nonstop1h 34m
Allegiant Air
Deal found 5/2$157
This Cheapflightsfares deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:26 pm
MYR
-
MDT
Nonstop1h 34m
Allegiant Air
Sun 6/74:00 pm
MDT
-
MYR
Nonstop1h 36m
Allegiant Air
Deal found 5/2$158
This Cheapflightsfares deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:34 pm
MYR
-
MDT
Nonstop1h 34m
Allegiant Air
Sun 7/124:09 pm
MDT
-
MYR
Nonstop1h 35m
Allegiant Air
Deal found 5/4$174
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:57 pm
CLT
-
MDT
1 stop12h 47m
Multiple Airlines
Sun 5/315:57 pm
MDT
-
CLT
1 stop18h 08m
Multiple Airlines
Deal found 4/30$238
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/318:23 am
GSP
-
MDT
1 stop24h 21m
Allegiant Air
Wed 6/37:16 pm
MDT
-
GSP
1 stop19h 11m
Allegiant Air
Deal found 5/2$251

Find flight deals from South Carolina to Harrisburg

Keep the following information in mind while searching for South Carolina to Harrisburg flight deals. Data was last updated May 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$133
(Cheapflightsfares)

One-way from

$56
(Trip.com)

Popular in

March

Cheapest in

September

Average price

$278
Provider with most accurate pricing for Myrtle Beach Intl-Harrisburg flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Harrisburg flights.
Search Deals
From South Carolina to Harrisburg
Search Deals
One-way flight from South Carolina to Harrisburg
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($58 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
Use the filters below to find and compare flights from South Carolina to Harrisburg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachHarrisburg

MYR - MDT

MYRMDT

Myrtle Beach Intl

Sat 6/6

8:44 pm-4:50 pm

2 stops44h 06m

Harrisburg

Sat 6/13

3:08 pm-4:44 pm

Nonstop1h 36m

$246

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Sun 5/31

8:23 am-8:44 am

1 stop24h 21m

Harrisburg

Wed 6/3

7:16 pm-2:27 pm

1 stop19h 11m

$251

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Thu 5/28

8:23 am-8:44 am

1 stop24h 21m

Harrisburg

Sun 5/31

5:57 pm-4:15 pm

1 stop22h 18m

$284

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Fri 10/23

5:40 am-11:36 am

1 stop5h 56m

Harrisburg

Sun 10/25

2:56 pm-8:14 pm

1 stop5h 18m

$289

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Fri 8/14

7:51 pm-11:25 pm

1 stop3h 34m

Harrisburg

Wed 8/19

6:30 am-1:38 pm

1 stop7h 08m

$289

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Tue 6/30

6:55 pm-11:10 pm

1 stop4h 15m

Harrisburg

Tue 7/14

6:22 pm-11:54 pm

1 stop5h 32m

$289

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Tue 6/9

7:10 am-11:42 am

1 stop4h 32m

Harrisburg

Fri 6/19

6:22 pm-11:59 pm

1 stop5h 37m

$289

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Wed 7/1

5:44 am-11:11 am

1 stop5h 27m

Harrisburg

Wed 7/15

6:22 pm-11:54 pm

1 stop5h 32m

$289

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Sat 6/27

7:10 am-11:42 am

1 stop4h 32m

Harrisburg

Mon 6/29

6:22 pm-10:43 pm

1 stop4h 21m

$292

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Fri 5/29

7:59 pm-11:51 pm

1 stop3h 52m

Harrisburg

Mon 6/1

6:33 pm-10:29 pm

1 stop3h 56m

$297

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/3

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Harrisburg

What is the cheapest month to book a flight from South Carolina to Harrisburg?

Currently, June is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $98). Flying from South Carolina to Harrisburg in March is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from South Carolina to Harrisburg?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Harrisburg from South Carolina?

    Harrisburg (MDT) is the airport you will fly into if you book a flight from South Carolina to Harrisburg. It is only a 8.5 mi journey from Harrisburg (MDT) to Harrisburg’s city center.

  • How long is the flight from South Carolina to Harrisburg?

    Allegiant Air, Delta, and United Airlines can get you from South Carolina to Harrisburg in just under 1h 34m. Your travel time can differ by up to 4h 22m. The distance from South Carolina to Harrisburg is about 465 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from South Carolina to Harrisburg?

    When deciding which route to take from South Carolina to Harrisburg consider Charlotte Douglas - Harrisburg, Charleston - Harrisburg or Savannah/Hilton Head - Harrisburg as they are the most popular.

  • Can I find deals for flights from South Carolina to Harrisburg that include hotel bookings?

    Yes. In addition to deals on South Carolina to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Harrisburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Harrisburg.

  • Can I find deals for business class flights from South Carolina to Harrisburg?

    Yes. Cheapflights offers flight deals from South Carolina to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Harrisburg?

    Currently, June is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $98). Flying from South Carolina to Harrisburg in March is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Mechanicsburg
Hershey
Camp Hill
Carlisle

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Harrisburg

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from South Carolina to Harrisburg

Discover the top 4 airlines that operate flights from South Carolina to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$101Average$156FlexibilityNo cancel feeOn-time88%
DeltaCheapest$220Average$335FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$417FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$238Average$420FlexibilityNo cancel feeOn-time69%

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