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Harrisburg

$87+ Cheap flights from South Carolina to Harrisburg (MDT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDT
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from South Carolina to Harrisburg

Cheapest flights from South Carolina to Harrisburg
Explore the most affordable flight options available from South Carolina to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1011:33 amCHS - MDT
1 stop5h 20mUnited Airlines
Sun 12/148:20 amMDT - CHS
1 stop5h 35mUnited Airlines
Deal found 12/3$269
This United Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/244:59 pmCHS - MDT
1 stop7h 08mUnited Airlines
Thu 12/2510:30 amMDT - CHS
1 stop4h 52mUnited Airlines
Deal found 12/1$273
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/168:05 amCHS - MDT
2 stops6h 19mAmerican Airlines
Sat 12/205:00 amMDT - CHS
1 stop3h 35mAmerican Airlines
Deal found 12/2$274
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/78:11 pmMYR - MDT
1 stop4h 07mAmerican Airlines
Sat 1/104:49 pmMDT - MYR
1 stop6h 49mAmerican Airlines
Deal found 12/3$274
This Delta deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:56 pmMYR - MDT
1 stop4h 17mDelta
Thu 12/186:00 amMDT - MYR
1 stop4h 34mDelta
Deal found 12/3$279
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:08 pmMYR - MDT
1 stop6h 10mAmerican Airlines
Thu 12/186:49 amMDT - MYR
2 stops7h 15mAmerican Airlines
Deal found 12/3$284
This Delta deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:27 pmSAV - MDT
1 stop5h 46mDelta
Wed 12/1712:41 pmMDT - SAV
1 stop4h 56mDelta
Deal found 12/3$293
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:43 pmMYR - MDT
1 stop3h 34mAmerican Airlines
Mon 12/154:25 pmMDT - MYR
1 stop6h 12mAmerican Airlines
Deal found 12/3$309
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:00 amGSP - MDT
1 stop4h 37mAmerican Airlines
Sat 1/36:42 amMDT - GSP
1 stop4h 05mAmerican Airlines
Deal found 12/3$310
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:44 amCHS - MDT
1 stop3h 51mAmerican Airlines
Tue 12/307:34 pmMDT - CHS
1 stop4h 31mAmerican Airlines
Deal found 12/2$312
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:51 pmCHS - MDT
1 stop4h 03mUnited Airlines
Wed 12/1010:40 amMDT - CHS
1 stop4h 30mUnited Airlines
Deal found 12/2$319
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/179:54 amMYR - MDT
2 stops22h 46mMultiple Airlines
Sun 12/2111:11 amMDT - MYR
1 stop7h 26mMultiple Airlines
Deal found 12/2$333

Find flight deals from South Carolina to Harrisburg

Keep the following information in mind while searching for South Carolina to Harrisburg flight deals. Data was last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$199
(American Airlines)

One-way from

$87
(Frontier)

Popular in

February

Cheapest in

September

Average price

$298
Provider with most accurate pricing for Myrtle Beach Intl-Harrisburg flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Harrisburg flights.
Search Deals
From South Carolina to Harrisburg
Search Deals
One-way flight from South Carolina to Harrisburg
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($79 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from South Carolina to Harrisburg that are best for you.

Fly from

South Carolina

Fly to

Harrisburg

Route

Depart

Return

Price

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Thu 1/29

5:23 pm-10:27 pm

1 stop5h 04m

Harrisburg

Sun 2/1

10:42 am-4:35 pm

1 stop5h 53m

$199

CharlotteHarrisburg

CLT - MDT

CLTMDT

Charlotte Douglas

Thu 1/22

9:58 pm-10:32 am

1 stop12h 34m

Harrisburg

Sun 1/25

7:50 pm-6:55 pm

1 stop23h 05m

$201

Myrtle BeachHarrisburg

MYR - MDT

MYRMDT

Myrtle Beach Intl

Fri 1/2

6:43 pm-10:12 pm

1 stop3h 29m

Harrisburg

Mon 1/5

7:34 pm-11:55 pm

1 stop4h 21m

$229

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Fri 1/16

4:07 pm-10:27 pm

1 stop6h 20m

Harrisburg

Fri 1/23

5:47 am-11:39 am

1 stop5h 52m

$249

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Thu 1/29

10:18 am-4:02 pm

1 stop5h 44m

Harrisburg

Sun 2/1

6:25 am-10:26 am

1 stop4h 01m

$249

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Sun 1/18

8:00 am-2:38 pm

2 stops6h 38m

Harrisburg

Thu 1/22

5:47 am-11:39 am

1 stop5h 52m

$258

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Sat 2/14

9:40 am-4:44 pm

1 stop7h 04m

Harrisburg

Wed 2/18

6:15 am-10:48 am

1 stop4h 33m

$265

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Wed 12/10

11:33 am-4:53 pm

1 stop5h 20m

Harrisburg

Sun 12/14

8:20 am-1:55 pm

1 stop5h 35m

$269

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Tue 12/16

12:09 pm-3:30 pm

1 stop3h 21m

Harrisburg

Sat 12/20

5:00 am-8:35 am

1 stop3h 35m

$269

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Wed 12/24

4:59 pm-12:07 am

1 stop7h 08m

Harrisburg

Thu 12/25

10:30 am-3:22 pm

1 stop4h 52m

$273

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/2

Showing 1-10 of 59 results
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Best time to book a flight from South Carolina to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Harrisburg

What is the cheapest month to book a flight from South Carolina to Harrisburg?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $97). Flying from South Carolina to Harrisburg in March is currently the most expensive (average of $184). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MDT?

Find hourly flight availability from South Carolina to Harrisburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

A simple way to save on the total cost of your ticket is to fly from South Carolina to Harrisburg in the evening. If you’re flexible enough to do this you can expect to save up to 30% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from South Carolina to Harrisburg?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Harrisburg. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Harrisburg flight should consider departing on Saturday afternoons when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from South Carolina to Harrisburg?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Harrisburg from South Carolina?

    Harrisburg (MDT) is the airport you will fly into if you book a flight from South Carolina to Harrisburg. It is only a 8.5 mi journey from Harrisburg (MDT) to Harrisburg’s city center.

  • How long is the flight from South Carolina to Harrisburg?

    American Airlines, Frontier, and United Airlines can get you from South Carolina to Harrisburg in just under 5h 04m. Your travel time can differ by up to 7h 30m. The distance from South Carolina to Harrisburg is about 609 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Harrisburg one-way?

    One-way options have recently been found by users for as low as $268 on Delta. Other airlines that offer cheap prices include American Airlines from $273 and Aeromexico from $389 one-way.

  • What are the most popular routes from South Carolina to Harrisburg?

    When deciding which route to take from South Carolina to Harrisburg consider Myrtle Beach Intl - Harrisburg, Charlotte Douglas - Harrisburg or Charleston - Harrisburg as they are the most popular.

  • Can I find deals for flights from South Carolina to Harrisburg that include hotel bookings?

    Yes. In addition to deals on South Carolina to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Harrisburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Harrisburg.

  • Can I find deals for business class flights from South Carolina to Harrisburg?

    Yes. Cheapflights offers flight deals from South Carolina to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Harrisburg?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $97). Flying from South Carolina to Harrisburg in March is currently the most expensive (average of $184). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Mechanicsburg
Hershey
Carlisle
Camp Hill

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Top 4 airlines flying from South Carolina to Harrisburg

Discover the top 4 airlines that operate flights from South Carolina to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$101Average$131FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$213Average$347FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$307FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$238Average$392FlexibilityNo cancel feeOn-time69%

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