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$74+ Cheap flights from South Carolina to Harrisburg (MDT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDT
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from South Carolina to Harrisburg

Keep the following information in mind while searching for South Carolina to Harrisburg flight deals. Data was last updated September 11, 2025.

Round-trip from

$197
(Booking.com)

One-way from

$74
(Cheapflightsfares)

Popular in

February

Cheapest in

July

Average price

$191
From South Carolina to Harrisburg
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One-way flight from South Carolina to Harrisburg
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Highest demand for flights based on searches. 20% potential increase in price ($70 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from South Carolina to Harrisburg

Cheapest flights from South Carolina to Harrisburg
Explore the most affordable flight options available from South Carolina to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/315:34 pmCHS - MDT
1 stop4h 13mAmerican Airlines
Mon 11/35:40 amMDT - CHS
1 stop4h 06mAmerican Airlines
Deal found 9/9$224
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/155:36 pmGSP - MDT
1 stop5h 32mDelta
Sat 10/186:00 amMDT - GSP
1 stop6h 47mDelta
Deal found 9/11$229
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:00 amGSP - MDT
1 stop4h 24mAmerican Airlines
Tue 11/112:55 pmMDT - GSP
2 stops8h 05mAmerican Airlines
Deal found 9/9$234
This Frontier deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1712:05 pmCLT - MDT
1 stop5h 31mFrontier
Mon 10/206:31 pmMDT - CLT
2 stops13h 22mFrontier
Deal found 9/9$239
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/237:05 pmCHS - MDT
1 stop4h 03mDelta
Mon 10/276:25 pmMDT - CHS
1 stop5h 34mDelta
Deal found 9/11$249
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/310:57 amSAV - MDT
1 stop4h 15mAmerican Airlines
Tue 10/73:07 pmMDT - SAV
1 stop6h 50mAmerican Airlines
Deal found 9/9$249
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/97:34 pmCLT - MDT
1 stop13h 04mMultiple Airlines
Sat 10/119:12 pmMDT - CLT
1 stop10h 48mMultiple Airlines
Deal found 9/10$251
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/249:00 amGSP - MDT
1 stop5h 21mAmerican Airlines
Tue 9/307:30 amMDT - GSP
1 stop4h 58mAmerican Airlines
Deal found 9/11$254
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/177:20 amCLT - MDT
1 stop10h 16mMultiple Airlines
Mon 10/206:31 pmMDT - CLT
1 stop13h 16mMultiple Airlines
Deal found 9/9$255
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1012:09 pmMYR - MDT
1 stop3h 21mAmerican Airlines
Sat 12/133:48 pmMDT - MYR
1 stop6h 17mAmerican Airlines
Deal found 9/9$259
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/107:03 pmSAV - MDT
1 stop3h 39mAmerican Airlines
Sat 9/134:45 pmMDT - SAV
1 stop6h 16mAmerican Airlines
Deal found 9/9$267
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/84:00 pmCLT - MDT
1 stop22h 47mMultiple Airlines
Sat 10/119:12 pmMDT - CLT
1 stop10h 48mMultiple Airlines
Deal found 9/11$267

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from South Carolina to Harrisburg that are best for you.

Fly from

South Carolina

Fly to

Harrisburg

Route

Depart

Return

Price

CharlotteHarrisburg

CLT - MDT

CLTMDT

Charlotte Douglas

Thu 9/25

8:51 pm-10:12 am

1 stop13h 21m

Harrisburg

Mon 9/29

10:57 am-1:32 pm

2 stops26h 35m

$197

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Fri 10/31

5:34 pm-9:47 pm

1 stop4h 13m

Harrisburg

Mon 11/3

5:40 am-9:46 am

1 stop4h 06m

$224

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Wed 10/15

5:36 pm-11:08 pm

1 stop5h 32m

Harrisburg

Mon 10/20

6:25 pm-10:18 pm

1 stop3h 53m

$229

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Thu 11/6

6:00 am-10:24 am

1 stop4h 24m

Harrisburg

Tue 11/11

4:25 pm-11:00 pm

1 stop6h 35m

$229

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Wed 10/1

6:02 am-10:13 am

1 stop4h 11m

Harrisburg

Sat 10/4

4:45 pm-10:58 pm

1 stop6h 13m

$229

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Thu 10/2

5:06 am-9:15 am

1 stop4h 09m

Harrisburg

Mon 10/6

6:15 am-10:20 am

1 stop4h 05m

$229

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Wed 10/8

5:35 am-10:59 am

1 stop5h 24m

Harrisburg

Wed 10/15

6:00 am-10:20 am

1 stop4h 20m

$249

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Thu 10/23

7:05 pm-11:08 pm

1 stop4h 03m

Harrisburg

Mon 10/27

6:25 pm-10:41 pm

1 stop4h 16m

$249

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Wed 10/1

5:03 pm-11:46 pm

1 stop6h 43m

Harrisburg

Mon 10/6

6:25 pm-11:58 pm

1 stop5h 33m

$249

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Fri 10/3

7:03 pm-10:42 pm

1 stop3h 39m

Harrisburg

Tue 10/7

3:07 pm-9:57 pm

1 stop6h 50m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Harrisburg

What is the cheapest month to book a flight from South Carolina to Harrisburg?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $347). Flying from South Carolina to Harrisburg in November is currently the most expensive (average of $408). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MDT?

Find hourly flight availability from South Carolina to Harrisburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from South Carolina to Harrisburg, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from South Carolina to Harrisburg?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Harrisburg from South Carolina?

    Harrisburg (MDT) is the airport you will fly into if you book a flight from South Carolina to Harrisburg. It is only a 8.5 mi journey from Harrisburg (MDT) to Harrisburg’s city center.

  • How long is the flight from South Carolina to Harrisburg?

    Frontier, American Airlines, and Delta can get you from South Carolina to Harrisburg in just under 4h 13m. Your travel time can differ by up to 9h 08m. The distance from South Carolina to Harrisburg is about 536 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Harrisburg one-way?

    One-way options have recently been found by users for as low as $74 on Allegiant Air. Other airlines that offer cheap prices include Frontier from $86 and American Airlines from $166 one-way.

  • What are the most popular routes from South Carolina to Harrisburg?

    When deciding which route to take from South Carolina to Harrisburg consider Charlotte Douglas - Harrisburg, Myrtle Beach Intl - Harrisburg or Savannah/Hilton Head - Harrisburg as they are the most popular.

  • Can I find deals for flights from South Carolina to Harrisburg that include hotel bookings?

    Yes. In addition to deals on South Carolina to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Harrisburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Harrisburg.

  • Can I find deals for business class flights from South Carolina to Harrisburg?

    Yes. Cheapflights offers flight deals from South Carolina to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Harrisburg?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $347). Flying from South Carolina to Harrisburg in November is currently the most expensive (average of $408). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Carlisle
Mechanicsburg
Hershey
Camp Hill

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Alternative routes for South Carolina to Harrisburg

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Top 4 airlines flying from South Carolina to Harrisburg

Discover the top 4 airlines that operate flights from South Carolina to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$98Average$140FlexibilityNo cancel feeOn-time88%
DeltaCheapest$198Average$310FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$213Average$342FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$238Average$397FlexibilityNo cancel feeOn-time69%

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