HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Harrisburg

$79+ Cheap flights from South Carolina to Harrisburg (MDT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/29. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDT
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Harrisburg with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from South Carolina to Harrisburg

Cheapest flights from South Carolina to Harrisburg
Explore the most affordable flight options available from South Carolina to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/139:57 amCLT - MDT
1 stop24h 51mMultiple Airlines
Fri 11/148:57 pmMDT - CLT
1 stop15h 26mMultiple Airlines
Deal found 11/4$215
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/119:06 amSAV - MDT
1 stop5h 46mAmerican Airlines
Tue 12/1610:43 amMDT - SAV
1 stop7h 06mAmerican Airlines
Deal found 11/4$222
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:41 amSAV - MDT
2 stops9h 32mDelta
Tue 12/165:00 pmMDT - SAV
2 stops6h 59mDelta
Deal found 11/5$233
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/269:34 pmCLT - MDT
1 stop10h 46mMultiple Airlines
Tue 12/3010:56 amMDT - CLT
1 stop9h 33mMultiple Airlines
Deal found 11/5$243
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1111:31 amCHS - MDT
1 stop4h 42mDelta
Sun 12/146:00 amMDT - CHS
1 stop5h 45mDelta
Deal found 11/5$249
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:45 amGSP - MDT
1 stop4h 14mDelta
Mon 11/247:12 pmMDT - GSP
1 stop4h 33mDelta
Deal found 11/4$259
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:20 pmGSP - MDT
1 stop5h 59mAmerican Airlines
Mon 1/55:00 amMDT - GSP
1 stop3h 36mAmerican Airlines
Deal found 11/6$261
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:30 amCHS - MDT
1 stop4h 29mDelta
Sat 11/156:00 amMDT - CHS
1 stop7h 05mDelta
Deal found 11/6$269
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:56 pmMYR - MDT
1 stop4h 17mDelta
Sat 12/136:00 amMDT - MYR
1 stop4h 34mDelta
Deal found 11/4$269
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/188:00 amCHS - MDT
2 stops6h 29mAmerican Airlines
Thu 11/206:46 amMDT - CHS
1 stop4h 01mAmerican Airlines
Deal found 11/5$274
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/228:49 amCLT - MDT
2 stops23h 54mMultiple Airlines
Tue 11/2511:08 amMDT - CLT
1 stop21h 08mMultiple Airlines
Deal found 11/5$281
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:44 pmSAV - MDT
1 stop5h 24mDelta
Sat 11/226:00 amMDT - SAV
1 stop5h 21mDelta
Deal found 11/5$293

Cheap flight deals from South Carolina to Harrisburg

Keep the following information in mind while searching for South Carolina to Harrisburg flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$222
(American Airlines)

One-way from

$79
(Kiwi.com)

Popular in

February

Cheapest in

September

Average price

$383
Provider with most accurate pricing for Myrtle Beach Intl-Harrisburg flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Harrisburg flights.
Search Deals
From South Carolina to Harrisburg
Search Deals
One-way flight from South Carolina to Harrisburg
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($74 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from South Carolina to Harrisburg that are best for you.

Fly from

South Carolina

Fly to

Harrisburg

Route

Depart

Return

Price

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Tue 12/2

6:32 am-10:24 am

1 stop3h 52m

Harrisburg

Tue 12/9

5:40 am-9:55 am

1 stop4h 15m

$222

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Thu 12/11

9:06 am-2:52 pm

1 stop5h 46m

Harrisburg

Tue 12/16

10:43 am-5:49 pm

1 stop7h 06m

$222

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Thu 1/1

5:39 am-9:10 am

1 stop3h 31m

Harrisburg

Thu 1/8

6:25 am-10:33 am

1 stop4h 08m

$229

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Thu 12/11

6:41 am-4:13 pm

2 stops9h 32m

Harrisburg

Tue 12/16

12:41 pm-11:59 pm

2 stops11h 18m

$233

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Fri 12/26

6:05 am-2:08 pm

1 stop8h 03m

Harrisburg

Wed 12/31

6:30 am-2:09 pm

1 stop7h 39m

$249

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Thu 12/11

11:31 am-4:13 pm

1 stop4h 42m

Harrisburg

Sun 12/14

6:00 am-11:45 am

1 stop5h 45m

$249

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Thu 12/11

2:28 pm-6:32 pm

1 stop4h 04m

Harrisburg

Tue 12/16

7:27 pm-11:50 pm

1 stop4h 23m

$249

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Wed 12/3

5:38 pm-11:50 pm

1 stop6h 12m

Harrisburg

Sat 12/6

5:31 pm-11:57 pm

1 stop6h 26m

$249

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Thu 1/29

6:10 am-10:17 am

1 stop4h 07m

Harrisburg

Sun 2/1

5:47 am-9:48 am

1 stop4h 01m

$249

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Thu 1/29

7:00 am-12:03 pm

1 stop5h 03m

Harrisburg

Sun 2/1

10:42 am-4:35 pm

1 stop5h 53m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from South Carolina to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Harrisburg

What is the cheapest month to book a flight from South Carolina to Harrisburg?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $97). Flying from South Carolina to Harrisburg in March is currently the most expensive (average of $184). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MDT?

Find hourly flight availability from South Carolina to Harrisburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

A simple way to save on the total cost of your ticket is to fly from South Carolina to Harrisburg in the evening. If you’re flexible enough to do this you can expect to save up to 30% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from South Carolina to Harrisburg?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Harrisburg. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Harrisburg flight should consider departing on Saturday afternoons when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Harrisburg from South Carolina?

    Harrisburg (MDT) is the airport you will fly into if you book a flight from South Carolina to Harrisburg. It is only a 8.5 mi journey from Harrisburg (MDT) to Harrisburg’s city center.

  • How long is the flight from South Carolina to Harrisburg?

    American Airlines and Delta can get you from South Carolina to Harrisburg in just under 3h 52m. Your travel time can differ by up to 5h 40m. The distance from South Carolina to Harrisburg is about 609 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Harrisburg one-way?

    One-way options have recently been found by users for as low as $135 on Delta. Other airlines that offer cheap prices include Allegiant Air from $161 and United Airlines from $170 one-way.

  • What are the most popular routes from South Carolina to Harrisburg?

    When deciding which route to take from South Carolina to Harrisburg consider Charlotte Douglas - Harrisburg, Charleston - Harrisburg or Myrtle Beach Intl - Harrisburg as they are the most popular.

  • Can I find deals for flights from South Carolina to Harrisburg that include hotel bookings?

    Yes. In addition to deals on South Carolina to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Harrisburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Harrisburg.

  • Can I find deals for business class flights from South Carolina to Harrisburg?

    Yes. Cheapflights offers flight deals from South Carolina to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Harrisburg?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $97). Flying from South Carolina to Harrisburg in March is currently the most expensive (average of $184). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Mechanicsburg
Hershey
Carlisle
Camp Hill

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Harrisburg

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to John F Kennedy Intl flights
Dallas/Fort Worth to John F Kennedy Intl flights
Los Angeles to Newark flights
Dallas/Fort Worth to LaGuardia flights
Dallas/Fort Worth to Newark flights
O'Hare Intl to John F Kennedy Intl flights
San Francisco to John F Kennedy Intl flights
Fort Lauderdale to Newark flights
Los Angeles to LaGuardia flights
Hobby to LaGuardia flights
San Francisco to Newark flights
Atlanta to John F Kennedy Intl flights
Atlanta to LaGuardia flights
O'Hare Intl to LaGuardia flights
Hobby to Newark flights
Fort Lauderdale to John F Kennedy Intl flights
Miami to Newark flights
Miami to John F Kennedy Intl flights
Hobby to John F Kennedy Intl flights
Fort Lauderdale to LaGuardia flights
Orlando to John F Kennedy Intl flights
Seattle to John F Kennedy Intl flights
O'Hare Intl to Newark flights
Tampa to John F Kennedy Intl flights
Dallas/Fort Worth to Dulles Intl flights
Atlanta to Newark flights
San Francisco to LaGuardia flights
Tampa to LaGuardia flights
Austin to John F Kennedy Intl flights
Raleigh to John F Kennedy Intl flights
Denver to John F Kennedy Intl flights
George Bush Intcntl to John F Kennedy Intl flights
Miami to LaGuardia flights
Charlotte to John F Kennedy Intl flights
Detroit to John F Kennedy Intl flights
Tampa to Newark flights
George Bush Intcntl to Newark flights
San Diego to John F Kennedy Intl flights
Sky Harbor Intl to John F Kennedy Intl flights
George Bush Intcntl to LaGuardia flights
Denver to LaGuardia flights
Raleigh to LaGuardia flights
Austin to Newark flights
Orlando to LaGuardia flights
Minneapolis to John F Kennedy Intl flights
Orlando to Newark flights
Ontario to John F Kennedy Intl flights
Denver to Newark flights
Los Angeles to Dulles Intl flights
Seattle to Newark flights

Top 4 airlines flying from South Carolina to Harrisburg

Discover the top 4 airlines that operate flights from South Carolina to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$101Average$131FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$213Average$345FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$297FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$238Average$390FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.