HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Harrisburg

$86+ Cheap flights from South Carolina to Harrisburg (MDT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/11. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDT
Feb 23 — Mar 21
Mon 2/23
Mon 3/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Harrisburg with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Harrisburg

Cheapest flights from South Carolina to Harrisburg
Explore the most affordable flight options available from South Carolina to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 24, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/299:58 pm
CLT
-
MDT
1 stop12h 34m
Frontier
Sun 2/17:50 pm
MDT
-
CLT
1 stop13h 40m
Frontier
Deal found 1/22$151
This Kiwi.com deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/255:49 pm
CLT
-
MDT
1 stop23h 02m
Multiple Airlines
Mon 3/25:25 pm
MDT
-
CLT
1 stop15h 01m
Multiple Airlines
Deal found 1/23$208
This Kiwi.com deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2610:24 pm
CLT
-
MDT
1 stop11h 27m
Multiple Airlines
Mon 3/25:25 pm
MDT
-
CLT
1 stop15h 01m
Multiple Airlines
Deal found 1/23$213
This Kiwi.com deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:49 pm
CLT
-
MDT
1 stop16h 02m
Multiple Airlines
Sat 2/287:21 pm
MDT
-
CLT
1 stop13h 22m
Multiple Airlines
Deal found 1/23$219
This American Airlines deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/245:20 am
GSP
-
MDT
1 stop6h 41m
American Airlines
Sat 2/282:59 pm
MDT
-
GSP
1 stop6h 14m
American Airlines
Deal found 1/23$244
This United Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:42 pm
GSP
-
MDT
1 stop3h 46m
United Airlines
Mon 4/206:15 am
MDT
-
GSP
1 stop3h 43m
United Airlines
Deal found 1/22$249
This Delta deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:00 am
MYR
-
MDT
1 stop5h 16m
Delta
Sun 2/225:55 pm
MDT
-
MYR
1 stop6h 02m
Delta
Deal found 1/22$249
This Kiwi.com deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:35 pm
CHS
-
MDT
1 stop22h 01m
Multiple Airlines
Sun 3/810:16 pm
MDT
-
CHS
1 stop10h 27m
Multiple Airlines
Deal found 1/22$257
This Kiwi.com deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:07 am
CHS
-
MDT
2 stops37h 14m
Multiple Airlines
Mon 4/610:06 pm
MDT
-
CHS
1 stop10h 32m
Multiple Airlines
Deal found 1/23$258
This American Airlines deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/68:00 am
MYR
-
MDT
1 stop4h 13m
American Airlines
Mon 2/94:47 pm
MDT
-
MYR
1 stop6h 28m
American Airlines
Deal found 1/23$259
This Frontier deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/289:28 am
CLT
-
MDT
1 stop8h 58m
Frontier
Sat 3/1410:18 pm
MDT
-
CLT
1 stop9h 45m
Frontier
Deal found 1/22$261
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2011:26 am
SAV
-
MDT
1 stop7h 14m
United Airlines
Sat 10/246:30 am
MDT
-
SAV
1 stop7h 39m
United Airlines
Deal found 1/21$265

Find flight deals from South Carolina to Harrisburg

Keep the following information in mind while searching for South Carolina to Harrisburg flight deals. Data was last updated January 24, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$208
(Kiwi.com)

One-way from

$86
(Frontier)

Popular in

February

Cheapest in

September

Average price

$298
Provider with most accurate pricing for Myrtle Beach Intl-Harrisburg flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Harrisburg flights.
Search Deals
From South Carolina to Harrisburg
Search Deals
One-way flight from South Carolina to Harrisburg
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($68 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 24, 2026.
Use the filters below to find and compare flights from South Carolina to Harrisburg that are best for you.

Fly from

South Carolina

Fly to

Harrisburg

Route

Depart

Return

Price

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Tue 2/24

5:20 am-12:01 pm

1 stop6h 41m

Harrisburg

Sat 2/28

2:59 pm-9:13 pm

1 stop6h 14m

$244

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Fri 4/17

7:42 pm-11:28 pm

1 stop3h 46m

Harrisburg

Mon 4/20

6:15 am-9:58 am

1 stop3h 43m

$249

Myrtle BeachHarrisburg

MYR - MDT

MYRMDT

Myrtle Beach Intl

Fri 2/20

6:00 am-11:16 am

1 stop5h 16m

Harrisburg

Sun 2/22

5:55 pm-11:57 pm

1 stop6h 02m

$249

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Thu 3/5

6:35 pm-4:36 pm

1 stop22h 01m

Harrisburg

Sun 3/8

10:16 pm-8:43 am

1 stop10h 27m

$257

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Thu 4/2

8:07 am-9:21 pm

2 stops37h 14m

Harrisburg

Mon 4/6

10:06 pm-8:38 am

1 stop10h 32m

$258

Myrtle BeachHarrisburg

MYR - MDT

MYRMDT

Myrtle Beach Intl

Fri 2/6

8:00 am-12:13 pm

1 stop4h 13m

Harrisburg

Mon 2/9

4:47 pm-11:15 pm

1 stop6h 28m

$259

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Wed 5/20

9:50 am-1:55 pm

1 stop4h 05m

Harrisburg

Tue 5/26

2:30 pm-7:12 pm

1 stop4h 42m

$265

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Thu 3/19

5:56 pm-11:37 pm

1 stop5h 41m

Harrisburg

Mon 3/23

6:21 pm-12:16 am

1 stop5h 55m

$269

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Thu 2/19

10:58 am-2:34 pm

1 stop3h 36m

Harrisburg

Sun 2/22

5:06 pm-11:01 pm

1 stop5h 55m

$269

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Fri 2/13

10:00 am-4:44 pm

1 stop6h 44m

Harrisburg

Sat 2/14

6:29 am-1:52 pm

1 stop7h 23m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/23

Showing 1-10 of 58 results
1
2
3
...
6

Best time to book a flight from South Carolina to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Harrisburg

What is the cheapest month to book a flight from South Carolina to Harrisburg?

Currently, April is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $97). Flying from South Carolina to Harrisburg in March is currently the most expensive (average of $184). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Harrisburg from South Carolina?

    Harrisburg (MDT) is the airport you will fly into if you book a flight from South Carolina to Harrisburg. It is only a 8.5 mi journey from Harrisburg (MDT) to Harrisburg’s city center.

  • How long is the flight from South Carolina to Harrisburg?

    American Airlines, United Airlines, and Delta can get you from South Carolina to Harrisburg in just under 3h 46m. Your travel time can differ by up to 2h 55m. The distance from South Carolina to Harrisburg is about 472 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Harrisburg one-way?

    One-way options have recently been found by users for as low as $58 on Allegiant Air. Other airlines that offer cheap prices include American Airlines from $99 and Delta from $158 one-way.

  • What are the most popular routes from South Carolina to Harrisburg?

    When deciding which route to take from South Carolina to Harrisburg consider Charlotte Douglas - Harrisburg, Savannah/Hilton Head - Harrisburg or Charleston - Harrisburg as they are the most popular.

  • Can I find deals for flights from South Carolina to Harrisburg that include hotel bookings?

    Yes. In addition to deals on South Carolina to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Harrisburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Harrisburg.

  • Can I find deals for business class flights from South Carolina to Harrisburg?

    Yes. Cheapflights offers flight deals from South Carolina to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Harrisburg?

    Currently, April is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $97). Flying from South Carolina to Harrisburg in March is currently the most expensive (average of $184). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Mechanicsburg
Hershey
Carlisle
Camp Hill

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Harrisburg

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to John F Kennedy Intl flights
Dallas/Fort Worth to John F Kennedy Intl flights
Dallas/Fort Worth to LaGuardia flights
San Francisco to John F Kennedy Intl flights
Los Angeles to Newark flights
San Francisco to Newark flights
O'Hare Intl to John F Kennedy Intl flights
Los Angeles to LaGuardia flights
Hobby to John F Kennedy Intl flights
Orlando to John F Kennedy Intl flights
Dallas/Fort Worth to Newark flights
Atlanta to LaGuardia flights
Atlanta to John F Kennedy Intl flights
Fort Lauderdale to John F Kennedy Intl flights
Hobby to Newark flights
Miami to Newark flights
Miami to LaGuardia flights
Miami to John F Kennedy Intl flights
Hobby to LaGuardia flights
Fort Lauderdale to LaGuardia flights
Fort Lauderdale to Newark flights
O'Hare Intl to LaGuardia flights
Austin to John F Kennedy Intl flights
O'Hare Intl to Newark flights
George Bush Intcntl to John F Kennedy Intl flights
Orlando to LaGuardia flights
Atlanta to Newark flights
San Francisco to LaGuardia flights
Dallas/Fort Worth to Dulles Intl flights
Tampa to Newark flights
Los Angeles to Reagan-National flights
Denver to Newark flights
Tampa to LaGuardia flights
Denver to LaGuardia flights
Tampa to John F Kennedy Intl flights
Seattle to John F Kennedy Intl flights
West Palm Beach to Newark flights
George Bush Intcntl to Newark flights
Orlando to Newark flights
Denver to John F Kennedy Intl flights
Raleigh to John F Kennedy Intl flights
Charlotte to John F Kennedy Intl flights
Los Angeles to Dulles Intl flights
Sky Harbor Intl to John F Kennedy Intl flights
Seattle to Newark flights
Minneapolis to LaGuardia flights
Austin to Newark flights
Burbank to LaGuardia flights
Raleigh to LaGuardia flights
George Bush Intcntl to LaGuardia flights

Top 4 airlines flying from South Carolina to Harrisburg

Discover the top 4 airlines that operate flights from South Carolina to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$98Average$133FlexibilityNo cancel feeOn-time88%
DeltaCheapest$144Average$329FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$213Average$353FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$238Average$390FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights