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$77+ Cheap flights from South Carolina to Harrisburg (MDT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDT
Aug 22 — Aug 291
Fri 8/22
Fri 8/29
1 adult, Economy
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Cheap flight deals from South Carolina to Harrisburg

Keep the following information in mind while searching for South Carolina to Harrisburg flight deals. Data was last updated August 17, 2025.

Round-trip from

$121
(Booking.com)

One-way from

$77
(Frontier)

Popular in

February

Cheapest in

July

Average price

$228
From South Carolina to Harrisburg
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One-way flight from South Carolina to Harrisburg
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Highest demand for flights based on searches. 20% potential increase in price ($70 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from South Carolina to Harrisburg

Cheapest flights from South Carolina to Harrisburg
Explore the most affordable flight options available from South Carolina to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2025.

This Booking.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/142:36 pmMYR - MDT
Nonstop1h 31mAllegiant Air
Sun 9/2112:17 pmMDT - MYR
Nonstop1h 29mAllegiant Air
Deal found 8/15$121
This Booking.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/312:28 pmMYR - MDT
Nonstop1h 35mAllegiant Air
Thu 9/412:17 pmMDT - MYR
Nonstop1h 29mAllegiant Air
Deal found 8/16$132
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/19:52 amSAV - MDT
1 stop4h 29mAmerican Airlines
Mon 10/61:52 pmMDT - SAV
1 stop6h 05mAmerican Airlines
Deal found 8/16$222
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/16:35 amGSP - MDT
1 stop5h 20mAmerican Airlines
Mon 10/69:33 amMDT - GSP
1 stop3h 30mAmerican Airlines
Deal found 8/15$229
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/512:22 pmSAV - MDT
2 stops10h 38mDelta
Mon 11/105:58 pmMDT - SAV
1 stop6h 01mDelta
Deal found 8/14$238
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/37:28 pmCHS - MDT
1 stop3h 14mAmerican Airlines
Sun 10/510:06 amMDT - CHS
1 stop4h 22mAmerican Airlines
Deal found 8/15$249
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/38:15 amSAV - MDT
1 stop6h 11mAmerican Airlines
Sun 10/56:30 amMDT - SAV
1 stop3h 47mAmerican Airlines
Deal found 8/16$249
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/106:55 pmCHS - MDT
1 stop4h 13mDelta
Sun 10/126:00 amMDT - CHS
1 stop4h 20mDelta
Deal found 8/15$254
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/141:11 pmMYR - MDT
2 stops29h 03mMultiple Airlines
Sun 9/2112:17 pmMDT - MYR
Nonstop1h 29mMultiple Airlines
Deal found 8/15$255
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/38:15 amSAV - MDT
1 stop6h 11mAmerican Airlines
Tue 10/73:07 pmMDT - SAV
1 stop6h 50mAmerican Airlines
Deal found 8/14$257
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/196:19 pmSAV - MDT
1 stop4h 40mDelta
Tue 8/266:00 amMDT - SAV
1 stop5h 14mDelta
Deal found 8/16$265
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/66:59 pmSAV - MDT
1 stop4h 09mDelta
Wed 10/86:25 pmMDT - SAV
1 stop5h 33mDelta
Deal found 8/14$268

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2025.
Use the filters below to find and compare flights from South Carolina to Harrisburg that are best for you.

Fly from

South Carolina

Fly to

Harrisburg

Route

Depart

Return

Price

Myrtle BeachHarrisburg

MYR - MDT

MYRMDT

Myrtle Beach Intl

Sun 9/14

2:36 pm-4:07 pm

Nonstop1h 31m

Harrisburg

Sun 9/21

12:17 pm-1:46 pm

Nonstop1h 29m

$121

Myrtle BeachHarrisburg

MYR - MDT

MYRMDT

Myrtle Beach Intl

Sun 8/31

2:28 pm-4:03 pm

Nonstop1h 35m

Harrisburg

Thu 9/4

12:17 pm-1:46 pm

Nonstop1h 29m

$132

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Fri 10/3

7:03 pm-10:42 pm

1 stop3h 39m

Harrisburg

Tue 10/7

3:07 pm-9:57 pm

1 stop6h 50m

$222

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Wed 11/5

7:22 pm-11:53 pm

1 stop4h 31m

Harrisburg

Mon 11/10

5:21 am-9:55 am

1 stop4h 34m

$222

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Wed 10/1

9:52 am-2:21 pm

1 stop4h 29m

Harrisburg

Mon 10/6

1:52 pm-7:57 pm

1 stop6h 05m

$222

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Wed 10/1

6:35 am-11:55 am

1 stop5h 20m

Harrisburg

Mon 10/6

9:33 am-1:03 pm

1 stop3h 30m

$229

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Wed 11/5

12:22 pm-11:00 pm

2 stops10h 38m

Harrisburg

Mon 11/10

5:58 pm-11:59 pm

1 stop6h 01m

$238

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Wed 10/29

12:54 pm-5:30 pm

1 stop4h 36m

Harrisburg

Sun 11/2

5:00 am-9:20 am

1 stop4h 20m

$249

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Fri 11/7

6:31 pm-11:00 pm

1 stop4h 29m

Harrisburg

Tue 11/11

5:58 pm-11:41 pm

1 stop5h 43m

$249

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Thu 1/29

4:02 pm-9:57 pm

1 stop5h 55m

Harrisburg

Sun 2/1

7:54 pm-12:05 am

1 stop4h 11m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/16

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Harrisburg

What is the cheapest month to book a flight from South Carolina to Harrisburg?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $355). Flying from South Carolina to Harrisburg in November is currently the most expensive (average of $408). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MDT?

Find hourly flight availability from South Carolina to Harrisburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 17, 2025.

When flying from South Carolina to Harrisburg, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Harrisburg from South Carolina?

    Harrisburg (MDT) is the airport you will fly into if you book a flight from South Carolina to Harrisburg. It is only a 8.5 mi journey from Harrisburg (MDT) to Harrisburg’s city center.

  • What are the cheapest airlines to fly from South Carolina to Harrisburg one-way?

    One-way options have recently been found by users for as low as $77 on Frontier. Other airlines that offer cheap prices include Allegiant Air from $78 and Delta from $133 one-way.

  • What are the most popular routes from South Carolina to Harrisburg?

    When deciding which route to take from South Carolina to Harrisburg consider Charlotte Douglas - Harrisburg, Charleston - Harrisburg or Greenville - Harrisburg as they are the most popular.

  • Can I find deals for flights from South Carolina to Harrisburg that include hotel bookings?

    Yes. In addition to deals on South Carolina to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Harrisburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Harrisburg.

  • Can I find deals for business class flights from South Carolina to Harrisburg?

    Yes. Cheapflights offers flight deals from South Carolina to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Harrisburg?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $355). Flying from South Carolina to Harrisburg in November is currently the most expensive (average of $408). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Carlisle
Hershey
Mechanicsburg
Camp Hill

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Alternative routes for South Carolina to Harrisburg

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from South Carolina to Harrisburg

Discover the top 4 airlines that operate flights from South Carolina to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$98Average$131FlexibilityNo cancel feeOn-time88%
DeltaCheapest$198Average$280FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$213Average$336FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$397FlexibilityNo cancel feeOn-time69%

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