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Harrisburg

$70+ Cheap flights from South Carolina to Harrisburg (MDT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDT
Mar 6 — Mar 131
Fri 3/6
Fri 3/13
1 adult, Economy
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Cheap flight deals from South Carolina to Harrisburg

Cheapest flights from South Carolina to Harrisburg
Explore the most affordable flight options available from South Carolina to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/221:07 pm
CLT
-
MDT
1 stop20h 44m
Multiple Airlines
Tue 2/2411:27 am
MDT
-
CLT
1 stop22h 50m
Multiple Airlines
Deal found 2/3$238
This Frontier deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/289:28 am
CLT
-
MDT
1 stop8h 58m
Frontier
Sat 3/1410:18 pm
MDT
-
CLT
1 stop9h 45m
Frontier
Deal found 2/3$244
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:00 am
GSP
-
MDT
1 stop3h 26m
American Airlines
Wed 3/42:59 pm
MDT
-
GSP
1 stop5h 47m
American Airlines
Deal found 2/3$244
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2610:24 pm
CLT
-
MDT
1 stop10h 04m
Multiple Airlines
Sun 3/110:46 am
MDT
-
CLT
1 stop20h 03m
Multiple Airlines
Deal found 2/3$246
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/143:15 pm
MYR
-
MDT
1 stop6h 03m
United Airlines
Sun 4/196:15 am
MDT
-
MYR
1 stop8h 02m
United Airlines
Deal found 2/3$249
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:30 am
CHS
-
MDT
1 stop4h 46m
Delta
Tue 3/106:10 am
MDT
-
CHS
1 stop4h 27m
Delta
Deal found 2/2$254
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:55 pm
MYR
-
MDT
1 stop4h 32m
Delta
Sun 2/225:55 pm
MDT
-
MYR
1 stop6h 02m
Delta
Deal found 2/3$259
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2011:26 am
SAV
-
MDT
1 stop8h 04m
United Airlines
Sat 10/246:30 am
MDT
-
SAV
1 stop7h 39m
United Airlines
Deal found 2/3$265
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:56 am
CLT
-
MDT
1 stop8h 30m
Multiple Airlines
Sun 4/194:26 pm
MDT
-
CLT
1 stop17h 51m
Multiple Airlines
Deal found 2/3$265
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:00 pm
CHS
-
MDT
1 stop4h 27m
Delta
Sun 2/225:55 pm
MDT
-
CHS
1 stop5h 59m
Delta
Deal found 2/3$269
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:00 pm
SAV
-
MDT
1 stop6h 59m
United Airlines
Sun 3/86:15 am
MDT
-
SAV
1 stop8h 13m
United Airlines
Deal found 2/3$269
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:40 am
GSP
-
MDT
1 stop5h 30m
Delta
Sun 2/226:34 am
MDT
-
GSP
1 stop4h 39m
Delta
Deal found 2/2$269

Find flight deals from South Carolina to Harrisburg

Keep the following information in mind while searching for South Carolina to Harrisburg flight deals. Data was last updated February 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$238
(Kiwi.com)

One-way from

$70
(Frontier)

Popular in

February

Cheapest in

September

Average price

$384
Provider with most accurate pricing for Myrtle Beach Intl-Harrisburg flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Harrisburg flights.
Search Deals
From South Carolina to Harrisburg
Search Deals
One-way flight from South Carolina to Harrisburg
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($69 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from South Carolina to Harrisburg that are best for you.

Fly from

South Carolina

Fly to

Harrisburg

Route

Depart

Return

Price

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Sat 2/28

6:00 am-9:26 am

1 stop3h 26m

Harrisburg

Wed 3/4

2:59 pm-8:46 pm

1 stop5h 47m

$244

Myrtle BeachHarrisburg

MYR - MDT

MYRMDT

Myrtle Beach Intl

Tue 4/14

3:15 pm-9:18 pm

1 stop6h 03m

Harrisburg

Sun 4/19

6:15 am-2:17 pm

1 stop8h 02m

$249

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Fri 3/6

6:30 am-11:16 am

1 stop4h 46m

Harrisburg

Tue 3/10

6:10 am-10:37 am

1 stop4h 27m

$254

Myrtle BeachHarrisburg

MYR - MDT

MYRMDT

Myrtle Beach Intl

Fri 2/20

6:55 pm-11:27 pm

1 stop4h 32m

Harrisburg

Sun 2/22

5:55 pm-11:57 pm

1 stop6h 02m

$259

CharlotteHarrisburg

CLT - MDT

CLTMDT

Charlotte Douglas

Fri 4/17

8:56 am-5:26 pm

1 stop8h 30m

Harrisburg

Sun 4/19

4:26 pm-10:17 am

1 stop17h 51m

$265

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Fri 3/6

4:55 pm-11:59 pm

1 stop7h 04m

Harrisburg

Sun 3/8

6:15 am-12:05 pm

1 stop5h 50m

$269

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Thu 3/19

4:51 pm-11:41 pm

1 stop6h 50m

Harrisburg

Mon 3/23

6:32 pm-12:16 am

1 stop5h 44m

$269

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Fri 4/10

6:00 am-9:44 am

1 stop3h 44m

Harrisburg

Sun 4/12

6:15 am-10:23 am

1 stop4h 08m

$269

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Thu 2/19

7:00 pm-11:27 pm

1 stop4h 27m

Harrisburg

Sun 2/22

6:00 am-10:44 am

1 stop4h 44m

$269

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Fri 3/6

5:00 pm-11:59 pm

1 stop6h 59m

Harrisburg

Sun 3/8

6:15 am-2:28 pm

1 stop8h 13m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/4

Showing 1-10 of 52 results
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Best time to book a flight from South Carolina to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Harrisburg

What is the cheapest month to book a flight from South Carolina to Harrisburg?

Currently, April is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $97). Flying from South Carolina to Harrisburg in March is currently the most expensive (average of $186). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from South Carolina to Harrisburg?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Harrisburg from South Carolina?

    Harrisburg (MDT) is the airport you will fly into if you book a flight from South Carolina to Harrisburg. It is only a 8.5 mi journey from Harrisburg (MDT) to Harrisburg’s city center.

  • How long is the flight from South Carolina to Harrisburg?

    American Airlines, United Airlines, and Delta can get you from South Carolina to Harrisburg in just under 3h 26m. Your travel time can differ by up to 2h 37m. The distance from South Carolina to Harrisburg is about 472 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Harrisburg one-way?

    One-way options have recently been found by users for as low as $58 on Allegiant Air. Other airlines that offer cheap prices include American Airlines from $99 and United Airlines from $134 one-way.

  • What are the most popular routes from South Carolina to Harrisburg?

    When deciding which route to take from South Carolina to Harrisburg consider Charlotte Douglas - Harrisburg, Charleston - Harrisburg or Myrtle Beach Intl - Harrisburg as they are the most popular.

  • Can I find deals for flights from South Carolina to Harrisburg that include hotel bookings?

    Yes. In addition to deals on South Carolina to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Harrisburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Harrisburg.

  • Can I find deals for business class flights from South Carolina to Harrisburg?

    Yes. Cheapflights offers flight deals from South Carolina to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Harrisburg?

    Currently, April is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $97). Flying from South Carolina to Harrisburg in March is currently the most expensive (average of $186). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Mechanicsburg
Hershey
Camp Hill
Carlisle

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Harrisburg

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from South Carolina to Harrisburg

Discover the top 4 airlines that operate flights from South Carolina to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$98Average$133FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$213Average$353FlexibilityNo cancel feeOn-time71%
DeltaCheapest$220Average$345FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$238Average$360FlexibilityNo cancel feeOn-time69%

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