$160+ Cheap flights from South Carolina to Harrisburg (MDT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/21. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDT
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Harrisburg with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Carolina to HarrisburgExplore the most affordable flight options available from South Carolina to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from South Carolina to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:00 am -
1 stop4h 23m
Sun 11/221:57 pm -
1 stop3h 43m
Deal found 10/26![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/253:29 pm -
1 stop6h 04m
Wed 12/26:17 am -
1 stop7h 43m
Deal found 10/28![United Airlines logo]()
$332
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:33 pm -
1 stop5h 39m
Fri 12/257:15 am -
1 stop6h 24m
Deal found 10/28![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:12 am -
1 stop4h 06m
Sat 12/124:56 pm -
1 stop5h 51m
Deal found 10/25![American Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:59 pm -
1 stop4h 49m
Sat 12/126:00 am -
1 stop7h 23m
Deal found 10/29![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:17 pm -
1 stop4h 33m
Sun 11/156:00 am -
1 stop6h 52m
Deal found 10/26![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:42 pm -
1 stop6h 20m
Thu 11/128:00 am -
1 stop3h 45m
Deal found 10/29![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:43 pm -
1 stop4h 01m
Sun 11/156:15 am -
1 stop3h 47m
Deal found 10/27![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:34 pm -
1 stop3h 43m
Sat 12/54:56 pm -
1 stop5h 51m
Deal found 10/27![American Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:10 am -
1 stop4h 13m
Wed 12/29:56 am -
1 stop4h 12m
Deal found 10/28![American Airlines logo]()
$393
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:54 pm -
1 stop3h 50m
Mon 11/96:15 am -
1 stop3h 44m
Deal found 10/28![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:10 am -
1 stop4h 07m
Sat 11/72:56 pm -
1 stop5h 46m
Deal found 10/27![American Airlines logo]()
$401
Best flights from South Carolina to HarrisburgDiscover carefully curated flight deals from South Carolina to Harrisburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from South Carolina to Harrisburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:12 am -
1 stop4h 06m
Sat 12/124:56 pm -
1 stop5h 51m
Deal found 10/25![American Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:59 pm -
1 stop4h 49m
Sat 12/126:00 am -
1 stop7h 23m
Deal found 10/29![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:43 pm -
1 stop4h 01m
Sun 11/156:15 am -
1 stop3h 47m
Deal found 10/27![United Airlines logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/243:51 pm -
1 stop16h 56m
Mon 11/303:50 pm -
1 stop23h 39m
Deal found 10/29![Multiple Airlines logo]()
$536
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:32 pm -
1 stop3h 44m
Sun 11/157:05 pm -
1 stop4h 47m
Deal found 10/29![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/62:42 pm -
1 stop4h 02m
Sat 1/92:59 pm -
1 stop4h 09m
Deal found 10/29![United Airlines logo]()
$425
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:54 pm -
1 stop3h 50m
Sun 11/156:15 am -
1 stop3h 44m
Deal found 10/27![United Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:54 pm -
1 stop6h 23m
Sat 12/1212:45 pm -
1 stop3h 48m
Deal found 10/30![American Airlines logo]()
$441
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:54 pm -
1 stop3h 50m
Tue 11/172:10 pm -
1 stop6h 52m
Deal found 10/29![United Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:54 pm -
1 stop6h 23m
Sat 12/1212:45 pm -
1 stop3h 48m
Deal found 10/29![American Airlines logo]()
$441
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/242:46 pm -
1 stop27h 33m
Tue 12/299:15 am -
2 stops24h 13m
Deal found 10/26![Multiple Airlines logo]()
$567
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:05 am -
1 stop4h 18m
Sat 11/287:17 pm -
1 stop4h 27m
Deal found 10/25![American Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2310:23 am -
1 stop3h 35m
Sat 11/286:15 am -
1 stop3h 54m
Deal found 10/25![United Airlines logo]()
$453
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
2 stops10h 18m
Wed 11/186:00 am -
1 stop4h 40m
Deal found 10/30![Delta logo]()
$613
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:39 pm -
1 stop4h 10m
Wed 12/307:52 am -
1 stop4h 15m
Deal found 10/28![American Airlines logo]()
$458
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:20 am -
1 stop7h 04m
Sat 11/146:15 am -
1 stop3h 47m
Deal found 10/26![United Airlines logo]()
$459
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:51 pm -
1 stop4h 59m
Wed 11/1812:09 pm -
2 stops10h 45m
Deal found 10/27![Delta logo]()
$632
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:43 pm -
1 stop4h 01m
Tue 11/178:15 am -
1 stop5h 15m
Deal found 10/29![United Airlines logo]()
$459
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/243:51 pm -
1 stop28h 36m
Sun 11/293:57 pm -
2 stops16h 16m
Deal found 10/27![Multiple Airlines logo]()
$679
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:35 pm -
1 stop3h 41m
Wed 11/186:00 am -
1 stop3h 26m
Deal found 10/27![American Airlines logo]()
$467
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:26 am -
1 stop3h 32m
Mon 11/232:10 pm -
1 stop6h 48m
Deal found 10/26![United Airlines logo]()
$464
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/92:18 pm -
2 stops8h 52m
Fri 12/116:00 am -
1 stop4h 41m
Deal found 10/26![Delta logo]()
$690
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:10 am -
1 stop4h 13m
Wed 12/26:08 am -
2 stops7h 16m
Deal found 10/28![American Airlines logo]()
$500
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:35 am -
2 stops5h 54m
Sun 11/226:00 am -
2 stops7h 14m
Deal found 10/26![Delta logo]()
$691
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:18 pm -
2 stops8h 48m
Wed 12/26:00 am -
2 stops7h 33m
Deal found 10/28![Delta logo]()
$723
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/242:21 pm -
1 stop6h 54m
Tue 12/296:20 am -
2 stops29h 24m
Deal found 10/26![United Airlines logo]()
$646
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/173:02 pm -
2 stops7h 47m
Mon 1/41:47 pm -
1 stop4h 45m
Deal found 10/28![American Airlines logo]()
$665
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:54 pm -
1 stop3h 50m
Fri 11/138:13 pm -
1 stop13h 46m
Deal found 10/25![United Airlines logo]()
$648
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:18 pm -
2 stops8h 48m
Mon 11/306:00 am -
1 stop4h 40m
Deal found 10/29![Delta logo]()
$868
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:00 am -
1 stop4h 23m
Sat 11/285:00 am -
1 stop3h 29m
Deal found 10/25![American Airlines logo]()
$676
Last-minute flights from South Carolina to HarrisburgDiscover last-minute flight deals from South Carolina to Harrisburg. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Harrisburg. Data last updated October 30, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:10 am -
1 stop4h 07m
Sat 11/72:56 pm -
1 stop5h 46m
Deal found 10/27![American Airlines logo]()
$401
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:54 pm -
1 stop3h 50m
Mon 11/96:15 am -
1 stop3h 44m
Deal found 10/28![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:43 pm -
1 stop4h 01m
Sun 11/86:15 am -
1 stop3h 47m
Deal found 10/26![United Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:42 pm -
1 stop6h 20m
Thu 11/128:00 am -
1 stop3h 45m
Deal found 10/29![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/73:29 pm -
1 stop6h 04m
Sun 11/86:15 am -
1 stop3h 51m
Deal found 10/29![United Airlines logo]()
$410
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:02 am -
1 stop4h 40m
Sun 11/86:00 am -
1 stop4h 10m
Deal found 10/27![Delta logo]()
$415
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:17 pm -
1 stop4h 33m
Sun 11/156:00 am -
1 stop6h 52m
Deal found 10/26![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:43 pm -
1 stop4h 01m
Sun 11/156:15 am -
1 stop3h 47m
Deal found 10/27![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:00 am -
1 stop4h 23m
Sun 11/221:57 pm -
1 stop3h 43m
Deal found 10/26![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/253:29 pm -
1 stop6h 04m
Wed 12/26:17 am -
1 stop7h 43m
Deal found 10/28![United Airlines logo]()
$332
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:10 am -
1 stop4h 13m
Wed 12/29:56 am -
1 stop4h 12m
Deal found 10/28![American Airlines logo]()
$393
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:10 am -
1 stop4h 13m
Mon 11/305:46 pm -
1 stop4h 17m
Deal found 10/29![American Airlines logo]()
$418
One-way flights from South Carolina to HarrisburgSearch for one-way flight options from South Carolina to Harrisburg. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from South Carolina to Harrisburg. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:39 pm -
1 stop4h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![American Airlines logo]()
$160
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:05 am -
1 stop4h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![American Airlines logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/154:08 pm -
3 stops44h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/243:51 pm -
1 stop16h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Allegiant Air logo]()
$270
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:40 pm -
1 stop4h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![American Airlines logo]()
$274
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:52 pm -
1 stop3h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![United Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:10 pm -
2 stops21h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Multiple Airlines logo]()
$291
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/308:44 pm -
1 stop3h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![American Airlines logo]()
$293
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/247:43 pm -
1 stop4h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![United Airlines logo]()
$318
This deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/242:52 pm -
1 stop3h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:44 pm -
1 stop6h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Delta logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/192:57 pm -
2 stops21h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$331
Find flight deals from South Carolina to Harrisburg
Keep the following information in mind while searching for South Carolina to Harrisburg flight deals. Data was last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $319 (American Airlines) |
One-way from | $160 (American Airlines) |
Popular in | December |
Cheapest in | October |
Average price | $142 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from South Carolina to Harrisburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbiaHarrisburg
CAE Columbia Metropolitan - MDT Harrisburg
CAEMDT
Columbia Metropolitan
Mon 12/21
6:39 pm-10:49 pm
1 stop4h 10m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$160
CharlestonHarrisburg
CHS Charleston - MDT Harrisburg
CHSMDT
Charleston
Tue 11/24
5:05 am-9:23 am
1 stop4h 18m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$170
Myrtle BeachHarrisburg
MYR Myrtle Beach Intl - MDT Harrisburg
MYRMDT
Myrtle Beach Intl
Tue 12/15
4:08 pm-12:31 pm
3 stops44h 23m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$234
GreenvilleHarrisburg
GSP Greenville - MDT Harrisburg
GSPMDT
Greenville
Tue 11/24
3:51 pm-8:47 am
1 stop16h 56m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$270
ColumbiaHarrisburg
CAE Columbia Metropolitan - MDT Harrisburg
CAEMDT
Columbia Metropolitan
Sat 12/12
6:40 pm-10:49 pm
1 stop4h 09m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$274
CharlestonHarrisburg
CHS Charleston - MDT Harrisburg
CHSMDT
Charleston
Wed 11/25
2:52 pm-6:36 pm
1 stop3h 44m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$284
CharlestonHarrisburg
CHS Charleston - MDT Harrisburg
CHSMDT
Charleston
Mon 11/30
8:29 pm-12:13 am
1 stop3h 44m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$284
Quickest round-trip
Myrtle BeachHarrisburg
MYR Myrtle Beach Intl - MDT Harrisburg
MYRMDT
Myrtle Beach Intl
Mon 11/30
8:44 pm-12:13 am
1 stop3h 29m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$293
Myrtle BeachHarrisburg
MYR Myrtle Beach Intl - MDT Harrisburg
MYRMDT
Myrtle Beach Intl
Sat 12/19
11:11 am-2:42 pm
1 stop3h 31m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$293
GreenvilleHarrisburg
GSP Greenville - MDT Harrisburg
GSPMDT
Greenville
Tue 11/24
7:43 pm-11:44 pm
1 stop4h 01m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$318
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Harrisburg
Have a flexible travel schedule? Discover the best time to fly to Harrisburg from South Carolina with our price prediction graph.
CAE-MDT
MYR-MDT
GSP-MDT
CHS-MDT
HHH-MDT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Harrisburg
USSC-MDT
CAE-MDT
MYR-MDT
GSP-MDT
CHS-MDT
What is the cheapest month to book a flight from South Carolina to Harrisburg?
Currently, February is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $314). Flying from South Carolina to Harrisburg in March is currently the most expensive (average of $490). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Harrisburg?
Book flights to Harrisburg if you plan to visit one of these locationsHershey
Mechanicsburg
Camp Hill
Carlisle
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for South Carolina to Harrisburg
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Complete your trip
Complete your trip to Harrisburg by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Harrisburg by cabin class
Find flights from South Carolina to Harrisburg, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Harrisburg flights
Browse other South Carolina and Harrisburg flight options. Last updated on October 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
South Carolina to Harrisburg flights
Consider these flights traveling from South Carolina to Harrisburg.
Top 4 airlines flying from South Carolina to Harrisburg
Discover the top 4 airlines that operate flights from South Carolina to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$109 | Average$164 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$262 | Average$414 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$280 | Average$338 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$284 | Average$468 | FlexibilityNo cancel fee | On-time71% |