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Harrisburg

$93+ Cheap flights from South Carolina to Harrisburg (MDT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDT
Nov 12 — Nov 191
Wed 11/12
Wed 11/19
1 adult, Economy
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Find flight deals from South Carolina to Harrisburg

Cheapest flights from South Carolina to Harrisburg
Explore the most affordable flight options available from South Carolina to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 13, 2025.

This Trip.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/237:34 pmCLT - MDT
1 stop22h 02mFrontier
Mon 10/276:31 pmMDT - CLT
1 stop19h 01mFrontier
Deal found 10/12$185
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:00 amGSP - MDT
1 stop4h 24mAmerican Airlines
Tue 11/185:40 amMDT - GSP
1 stop3h 59mAmerican Airlines
Deal found 10/13$229
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:41 amSAV - MDT
1 stop4h 18mDelta
Mon 12/17:12 pmMDT - SAV
1 stop4h 52mDelta
Deal found 10/13$233
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/247:20 amCLT - MDT
1 stop10h 16mMultiple Airlines
Mon 10/276:31 pmMDT - CLT
1 stop13h 16mMultiple Airlines
Deal found 10/12$233
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2811:29 amGSP - MDT
1 stop4h 43mDelta
Sat 11/112:20 pmMDT - GSP
1 stop5h 21mDelta
Deal found 10/13$239
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:00 amGSP - MDT
2 stops5h 40mAmerican Airlines
Sat 11/19:33 amMDT - GSP
1 stop3h 30mAmerican Airlines
Deal found 10/13$244
This Delta deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:28 pmCHS - MDT
1 stop4h 04mDelta
Sun 12/76:00 amMDT - CHS
1 stop5h 45mDelta
Deal found 10/11$249
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/17:00 amSAV - MDT
1 stop4h 00mAmerican Airlines
Wed 11/55:40 amMDT - SAV
1 stop4h 56mAmerican Airlines
Deal found 10/12$254
This Kiwi.com deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/109:57 amCLT - MDT
1 stop10h 15mFrontier
Mon 11/178:57 pmMDT - CLT
1 stop16h 35mFrontier
Deal found 10/11$257
This Kiwi.com deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/169:20 pmCLT - MDT
1 stop22h 52mMultiple Airlines
Mon 12/19:17 pmMDT - CLT
1 stop16h 49mMultiple Airlines
Deal found 10/11$262
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1710:06 pmCLT - MDT
1 stop22h 16mMultiple Airlines
Mon 10/206:31 pmMDT - CLT
1 stop13h 16mMultiple Airlines
Deal found 10/12$272
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/238:48 amCLT - MDT
2 stops10h 43mMultiple Airlines
Mon 10/276:31 pmMDT - CLT
1 stop13h 16mMultiple Airlines
Deal found 10/12$275

Cheap flight deals from South Carolina to Harrisburg

Keep the following information in mind while searching for South Carolina to Harrisburg flight deals. Data was last updated October 13, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$185
(Trip.com)

One-way from

$104
(Cheapflightsfares)

Popular in

February

Cheapest in

September

Average price

$298
Provider with most accurate pricing for Myrtle Beach Intl-Harrisburg flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Harrisburg flights.
Search Deals
From South Carolina to Harrisburg
Search Deals
One-way flight from South Carolina to Harrisburg
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($74 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
Use the filters below to find and compare flights from South Carolina to Harrisburg that are best for you.

Fly from

South Carolina

Fly to

Harrisburg

Route

Depart

Return

Price

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Wed 2/18

9:40 am-4:44 pm

1 stop7h 04m

Harrisburg

Sat 2/21

2:07 pm-8:00 pm

1 stop5h 53m

$195

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Thu 11/13

6:00 am-10:24 am

1 stop4h 24m

Harrisburg

Tue 11/18

5:40 am-9:39 am

1 stop3h 59m

$229

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Wed 3/25

6:20 pm-10:47 pm

1 stop4h 27m

Harrisburg

Sat 3/28

6:25 pm-11:36 pm

1 stop5h 11m

$229

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Mon 11/24

6:41 am-10:59 am

1 stop4h 18m

Harrisburg

Mon 12/1

7:12 pm-12:04 am

1 stop4h 52m

$233

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Tue 10/28

11:29 am-4:12 pm

1 stop4h 43m

Harrisburg

Sat 11/1

12:20 pm-5:41 pm

1 stop5h 21m

$239

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Tue 10/28

6:00 am-11:40 am

2 stops5h 40m

Harrisburg

Sat 11/1

9:33 am-1:03 pm

1 stop3h 30m

$244

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Mon 11/10

7:12 pm-11:53 pm

1 stop4h 41m

Harrisburg

Mon 11/17

4:25 pm-9:06 pm

1 stop4h 41m

$249

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Thu 12/4

2:28 pm-6:32 pm

1 stop4h 04m

Harrisburg

Sun 12/7

6:00 am-11:45 am

1 stop5h 45m

$249

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Thu 1/29

5:21 pm-11:37 pm

1 stop6h 16m

Harrisburg

Sun 2/1

5:47 am-9:50 am

1 stop4h 03m

$249

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Sat 11/1

7:00 am-11:00 am

1 stop4h 00m

Harrisburg

Wed 11/5

5:40 am-10:36 am

1 stop4h 56m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/13

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Harrisburg

What is the cheapest month to book a flight from South Carolina to Harrisburg?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $97). Flying from South Carolina to Harrisburg in March is currently the most expensive (average of $184). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MDT?

Find hourly flight availability from South Carolina to Harrisburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 13, 2025.

A simple way to save on the total cost of your ticket is to fly from South Carolina to Harrisburg in the evening. If you’re flexible enough to do this you can expect to save up to 30% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from South Carolina to Harrisburg?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Harrisburg. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Harrisburg flight should consider departing on Saturday afternoons when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Harrisburg from South Carolina?

    Harrisburg (MDT) is the airport you will fly into if you book a flight from South Carolina to Harrisburg. It is only a 8.5 mi journey from Harrisburg (MDT) to Harrisburg’s city center.

  • How long is the flight from South Carolina to Harrisburg?

    United Airlines, American Airlines, and Delta can get you from South Carolina to Harrisburg in just under 4h 24m. Your travel time can differ by up to 2h 40m. The distance from South Carolina to Harrisburg is about 472 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Harrisburg one-way?

    One-way options have recently been found by users for as low as $93 on Allegiant Air. Other airlines that offer cheap prices include Frontier from $111 and American Airlines from $170 one-way.

  • What are the most popular routes from South Carolina to Harrisburg?

    When deciding which route to take from South Carolina to Harrisburg consider Charlotte Douglas - Harrisburg, Charleston - Harrisburg or Myrtle Beach Intl - Harrisburg as they are the most popular.

  • Can I find deals for flights from South Carolina to Harrisburg that include hotel bookings?

    Yes. In addition to deals on South Carolina to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Harrisburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Harrisburg.

  • Can I find deals for business class flights from South Carolina to Harrisburg?

    Yes. Cheapflights offers flight deals from South Carolina to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Harrisburg?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $97). Flying from South Carolina to Harrisburg in March is currently the most expensive (average of $184). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Mechanicsburg
Hershey
Carlisle
Camp Hill

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Alternative routes for South Carolina to Harrisburg

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from South Carolina to Harrisburg

Discover the top 4 airlines that operate flights from South Carolina to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$98Average$131FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$213Average$345FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$295FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$238Average$392FlexibilityNo cancel feeOn-time69%

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