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Guayaquil

$205+ Cheap flights from South Carolina to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GYE
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from South Carolina to Guayaquil

Keep the following information in mind while searching for South Carolina to Guayaquil flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$496
(United)

One-way from

$205
(Kiwi.com)
Provider with most accurate pricing for Myrtle Beach Intl-Guayaquil Jose Joaquin de Olmedo flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Guayaquil Jose Joaquin de Olmedo flights.
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From South Carolina to Guayaquil Jose Joaquin de Olmedo
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One-way flight from South Carolina to Guayaquil Jose Joaquin de Olmedo
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Find flight deals from South Carolina to Guayaquil

Cheapest flights from South Carolina to Guayaquil
Explore the most affordable flight options available from South Carolina to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This United deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/107:00 amCLT - GYE
2 stops35h 20mMultiple Airlines
Mon 9/293:35 amGYE - CLT
2 stops30h 19mMultiple Airlines
Deal found 4/29$496
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/105:35 amCLT - GYE
1 stop14h 25mAmerican Airlines
Tue 9/307:30 amGYE - CLT
1 stop9h 00mAmerican Airlines
Deal found 4/29$501
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:30 amCLT - GYE
2 stops31h 22mUnited Airlines
Sat 12/133:55 amGYE - CLT
2 stops34h 09mUnited Airlines
Deal found 4/29$556
This United deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/296:29 pmCHS - GYE
2 stops16h 26mMultiple Airlines
Thu 6/122:45 pmGYE - CHS
2 stops32h 03mMultiple Airlines
Deal found 4/29$599
This Avianca Connect deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/86:00 amMYR - GYE
2 stops17h 40mMultiple Airlines
Mon 6/234:15 amGYE - MYR
2 stops14h 07mMultiple Airlines
Deal found 4/30$636
This Copa Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/126:00 amCLT - GYE
2 stops18h 37mCopa Airlines
Mon 6/166:31 pmGYE - CLT
2 stops14h 19mCopa Airlines
Deal found 4/30$697
This JetBlue deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/296:58 pmCHS - GYE
1 stop10h 45mJetBlue
Thu 6/127:29 amGYE - CHS
1 stop9h 35mJetBlue
Deal found 4/29$744
This FlightHub deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/16:00 amCLT - GYE
2 stops21h 05mAvianca
Fri 5/93:15 amGYE - CLT
2 stops29h 30mAvianca
Deal found 4/29$795
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/297:40 amCHS - GYE
2 stops14h 30mAmerican Airlines
Thu 6/126:00 amGYE - CHS
1 stop26h 46mAmerican Airlines
Deal found 4/29$961

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from South Carolina to Guayaquil that are best for you.

Fly from

South Carolina

Fly to

Guayaquil

Route

Depart

Return

Price

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Wed 9/10

7:00 am-5:20 pm

2 stops35h 20m

Guayaquil Jose Joaquin de Olmedo

Mon 9/29

3:35 am-10:54 am

2 stops30h 19m

$496

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Wed 9/10

5:35 am-7:00 pm

1 stop14h 25m

Guayaquil Jose Joaquin de Olmedo

Tue 9/30

7:30 am-5:30 pm

1 stop9h 00m

$501

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Thu 5/29

6:29 pm-9:55 am

2 stops16h 26m

Guayaquil Jose Joaquin de Olmedo

Thu 6/12

2:45 pm-11:48 pm

2 stops32h 03m

$599

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Fri 6/13

7:00 am-11:37 pm

2 stops17h 37m

Guayaquil Jose Joaquin de Olmedo

Fri 6/20

8:31 am-10:00 pm

2 stops36h 29m

$605

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

Sun 6/8

6:00 am-10:40 pm

2 stops17h 40m

Guayaquil Jose Joaquin de Olmedo

Mon 6/23

4:15 am-7:22 pm

2 stops14h 07m

$636

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Thu 6/12

6:00 am-11:37 pm

2 stops18h 37m

Guayaquil Jose Joaquin de Olmedo

Mon 6/16

6:31 pm-9:50 am

2 stops14h 19m

$697

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Thu 5/29

6:58 pm-4:43 am

1 stop10h 45m

Guayaquil Jose Joaquin de Olmedo

Thu 6/12

7:29 am-6:04 pm

1 stop9h 35m

$744

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Sun 5/11

6:00 am-11:20 pm

2 stops18h 20m

Guayaquil Jose Joaquin de Olmedo

Sat 5/24

6:30 pm-9:50 am

2 stops14h 20m

$830

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Thu 5/29

7:40 am-9:10 pm

2 stops14h 30m

Guayaquil Jose Joaquin de Olmedo

Thu 6/12

6:00 am-9:46 am

1 stop26h 46m

$961

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Sun 5/18

6:46 pm-5:20 pm

2 stops23h 34m

$205

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Showing 1-10 of 16 results
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Best time to book a flight from South Carolina to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Guayaquil

What is the cheapest time of day to fly from SC to GYE?

Find hourly flight availability from South Carolina to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

When flying from South Carolina to Guayaquil, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Guayaquil by month

Plan your trip to Guayaquil by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Guayaquil ranges from 0.0 - 11.0 inches per month. March is typically the wettest month, when rainfall can reach 11.0 in. July is typically the driest time to visit Guayaquil when rainfall is around 0.0 in.

Temperature in Guayaquil by month

Plan your trip to Guayaquil by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Guayaquil, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 77.0 F).

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated May 1, 2025.
To help decide which airline to fly from South Carolina to Guayaquil, see what other customers have to say about LATAM Airlines, Copa Airlines and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,767 reviews

Overall

7.5

Boarding

7.6

Entertainment

7.0

Comfort

7.4

Food

6.7

Crew

8.1

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
LATAM Airlines
7.5
Good
1,767 reviews
LATAM Airlines
7.5
Good
1,767 reviews

Overall

7.5

Boarding

7.6

Entertainment

7.0

Comfort

7.4

Food

6.7

Crew

8.1

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
Copa Airlines
7.5
Good
1,415 reviews
LATAM Airlines
7.5
Good
1,767 reviews

Overall

7.5

Boarding

7.6

Entertainment

7.0

Comfort

7.4

Food

6.7

Crew

8.1

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
United Airlines
7.4
Good
8,696 reviews
LATAM Airlines
7.5
Good
1,767 reviews

Overall

7.5

Boarding

7.6

Entertainment

7.0

Comfort

7.4

Food

6.7

Crew

8.1

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
JetBlue
7.3
Good
2,922 reviews
LATAM Airlines
7.5
Good
1,767 reviews

Overall

7.5

Boarding

7.6

Entertainment

7.0

Comfort

7.4

Food

6.7

Crew

8.1

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
American Airlines
7.2
Good
10,000 reviews
LATAM Airlines
7.5
Good
1,767 reviews

Overall

7.5

Boarding

7.6

Entertainment

7.0

Comfort

7.4

Food

6.7

Crew

8.1

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from South Carolina?

    Guayaquil Jose Joaquin de Olmedo (GYE), located 2.5 mi from the city center, is the airport you fly into when you book flights from South Carolina to Guayaquil.

  • What are the cheapest airlines to fly from South Carolina to Guayaquil one-way?

    One-way options have recently been found by users for as low as $375 on Avianca. Other airlines that offer cheap prices include American Airlines from $509 and LATAM Airlines from $510 one-way.

  • What are the most popular routes from South Carolina to Guayaquil?

    The most popular route from South Carolina to Guayaquil is Charlotte Douglas - Guayaquil Jose Joaquin de Olmedo. You may also consider Charleston - Guayaquil Jose Joaquin de Olmedo or Myrtle Beach Intl - Guayaquil Jose Joaquin de Olmedo.

  • Can I find deals for flights from South Carolina to Guayaquil that include hotel bookings?

    Yes. In addition to deals on South Carolina to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Guayaquil.

  • Can I find deals for business class flights from South Carolina to Guayaquil?

    Yes. Cheapflights offers flight deals from South Carolina to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from South Carolina to Guayaquil (average of $440). Flying from South Carolina to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from South Carolina to Guayaquil

Discover the top airline that operate flights from South Carolina to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$436Average$682FlexibilityNo cancel feeOn-time71%

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