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Guayaquil

$170+ Cheap flights from South Carolina to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GYE
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
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Cheap flight deals from South Carolina to Guayaquil

Keep the following information in mind while searching for South Carolina to Guayaquil flight deals. Data was last updated August 18, 2025.

Round-trip from

$325
(FlightHub)

One-way from

$170
(Avianca Connect)
From South Carolina to Guayaquil Jose Joaquin de Olmedo
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One-way flight from South Carolina to Guayaquil Jose Joaquin de Olmedo
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Find flight deals from South Carolina to Guayaquil

Cheapest flights from South Carolina to Guayaquil
Explore the most affordable flight options available from South Carolina to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This FlightHub deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:45 amCLT - GYE
1 stop18h 00mSpirit Airlines
Sun 12/712:59 amGYE - CLT
1 stop8h 28mSpirit Airlines
Deal found 8/16$325
This Cheapflightsfares deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:49 amCLT - GYE
1 stop13h 56mSpirit Airlines
Sat 12/612:59 amGYE - CLT
1 stop8h 28mSpirit Airlines
Deal found 8/15$356
This Expedia deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/59:40 amCHS - GYE
1 stop28h 50mJetBlue
Sat 10/252:40 pmGYE - CHS
1 stop24h 42mJetBlue
Deal found 8/17$463
This Expedia deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:20 pmCHS - GYE
1 stop21h 00mJetBlue
Tue 11/183:30 pmGYE - CHS
1 stop24h 52mJetBlue
Deal found 8/16$514
This United deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/267:00 amCLT - GYE
2 stops40h 41mMultiple Airlines
Tue 12/23:30 amGYE - CLT
2 stops18h 29mMultiple Airlines
Deal found 8/18$532
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/247:00 amCLT - GYE
2 stops31h 46mUnited Airlines
Tue 10/1412:15 pmGYE - CLT
2 stops31h 57mUnited Airlines
Deal found 8/17$563
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/247:00 amCLT - GYE
2 stops31h 46mUnited Airlines
Wed 11/1212:21 pmGYE - CLT
2 stops33h 38mUnited Airlines
Deal found 8/16$572
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/133:34 pmCLT - GYE
2 stops42h 01mMultiple Airlines
Sat 11/16:50 pmGYE - CLT
1 stop27h 07mMultiple Airlines
Deal found 8/16$584
This United deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/147:00 amCLT - GYE
2 stops29h 15mMultiple Airlines
Sat 11/153:30 amGYE - CLT
2 stops18h 29mMultiple Airlines
Deal found 8/16$590
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/307:00 amCLT - GYE
2 stops17h 37mUnited Airlines
Tue 10/72:44 pmGYE - CLT
2 stops30h 15mUnited Airlines
Deal found 8/16$592
This Ovago deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/227:10 pmCHS - GYE
1 stop10h 05mJetBlue
Mon 12/13:30 pmGYE - CHS
1 stop17h 05mJetBlue
Deal found 8/15$606
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:05 pmCHS - GYE
2 stops30h 36mUnited Airlines
Tue 11/188:30 amGYE - CHS
2 stops37h 29mUnited Airlines
Deal found 8/16$635

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from South Carolina to Guayaquil that are best for you.

Fly from

South Carolina

Fly to

Guayaquil

Route

Depart

Return

Price

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Thu 12/4

5:45 am-11:45 pm

1 stop18h 00m

Guayaquil Jose Joaquin de Olmedo

Sun 12/7

12:59 am-9:27 am

1 stop8h 28m

$325

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Wed 2/11

9:49 am-11:45 pm

1 stop13h 56m

Guayaquil Jose Joaquin de Olmedo

Tue 2/17

12:59 am-9:27 am

1 stop8h 28m

$341

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Thu 12/4

9:49 am-11:45 pm

1 stop13h 56m

Guayaquil Jose Joaquin de Olmedo

Sat 12/6

12:59 am-9:27 am

1 stop8h 28m

$356

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Sun 10/5

9:40 am-1:30 pm

1 stop28h 50m

Guayaquil Jose Joaquin de Olmedo

Sat 10/25

2:40 pm-4:22 pm

1 stop24h 42m

$463

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Wed 11/5

5:20 pm-2:20 pm

1 stop21h 00m

Guayaquil Jose Joaquin de Olmedo

Tue 11/18

3:30 pm-4:22 pm

1 stop24h 52m

$514

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Sat 11/22

7:10 pm-5:15 am

1 stop10h 05m

Guayaquil Jose Joaquin de Olmedo

Mon 12/1

3:30 pm-8:35 am

1 stop17h 05m

$606

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Wed 11/5

5:05 pm-11:41 pm

2 stops30h 36m

Guayaquil Jose Joaquin de Olmedo

Tue 11/18

8:30 am-9:59 pm

2 stops37h 29m

$635

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Sun 10/5

6:38 pm-7:10 pm

2 stops25h 32m

Guayaquil Jose Joaquin de Olmedo

Sat 10/25

8:15 am-10:49 am

2 stops25h 34m

$637

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Fri 9/19

7:00 am-1:46 pm

2 stops31h 46m

Guayaquil Jose Joaquin de Olmedo

Mon 9/29

12:17 pm-10:15 pm

2 stops32h 58m

$645

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Fri 9/19

7:28 pm-7:48 pm

2 stops25h 20m

Guayaquil Jose Joaquin de Olmedo

Mon 9/29

8:20 am-11:37 pm

1 stop14h 17m

$675

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/16

Showing 1-10 of 19 results
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Best time to book a flight from South Carolina to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Guayaquil

What is the cheapest time of day to fly from SC to GYE?

Find hourly flight availability from South Carolina to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

When flying from South Carolina to Guayaquil, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from South Carolina?

    Guayaquil Jose Joaquin de Olmedo (GYE), located 2.5 mi from the city center, is the airport you fly into when you book flights from South Carolina to Guayaquil.

  • How long is the flight from South Carolina to Guayaquil?

    There are many flights that can get you from South Carolina to Guayaquil in 18h. Fly via Spirit Airlines, JetBlue, or United Airlines to get the fastest option. The distance from South Carolina to Guayaquil is about 2582 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Guayaquil?

    The most popular route from South Carolina to Guayaquil is Charlotte Douglas - Guayaquil Jose Joaquin de Olmedo. You may also consider Charleston - Guayaquil Jose Joaquin de Olmedo or Myrtle Beach Intl - Guayaquil Jose Joaquin de Olmedo.

  • Can I find deals for flights from South Carolina to Guayaquil that include hotel bookings?

    Yes. In addition to deals on South Carolina to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Guayaquil.

  • Can I find deals for business class flights from South Carolina to Guayaquil?

    Yes. Cheapflights offers flight deals from South Carolina to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from South Carolina to Guayaquil (average of $440). Flying from South Carolina to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from South Carolina to Guayaquil

Discover the top airline that operate flights from South Carolina to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$451Average$753FlexibilityNo cancel feeOn-time71%

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