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Guayaquil

$347+ Cheap flights from Columbus (CMH) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — GYE
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Columbus to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Columbus (CMH) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$490
(Avianca Connect)

One-way from

$347
(eDestinos)

Popular in

July

Cheapest in

March

Average price

$747
From Columbus to Guayaquil Jose Joaquin de Olmedo
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One-way flight from Columbus to Guayaquil Jose Joaquin de Olmedo
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High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 3% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Columbus to Guayaquil

Cheapest flights from Columbus to Guayaquil
Explore the most affordable flight options available from Columbus to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Avianca Connect deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/295:15 amCMH - GYE
2 stops19h 05mMultiple Airlines
Sat 10/254:15 amGYE - CMH
2 stops13h 23mMultiple Airlines
Deal found 9/14$490
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/315:00 amCMH - GYE
2 stops21h 05mMultiple Airlines
Wed 11/53:35 pmGYE - CMH
2 stops29h 37mMultiple Airlines
Deal found 9/16$543
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/295:15 amCMH - GYE
2 stops33h 25mMultiple Airlines
Mon 10/203:35 amGYE - CMH
3 stops27h 02mMultiple Airlines
Deal found 9/15$587
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:21 pmCMH - GYE
3 stops39h 54mMultiple Airlines
Wed 11/53:30 amGYE - CMH
2 stops17h 42mMultiple Airlines
Deal found 9/15$590
This Trip.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/95:00 amCMH - GYE
2 stops18h 40mMultiple Airlines
Tue 10/144:15 amGYE - CMH
3 stops33h 14mMultiple Airlines
Deal found 9/15$601

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Columbus Airport to Guayaquil that are best for you.

Fly from

Columbus

Fly to

Guayaquil

Route

Depart

Return

Price

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Mon 9/29

5:15 am-11:20 pm

2 stops19h 05m

Guayaquil Jose Joaquin de Olmedo

Sat 10/25

4:15 am-6:38 pm

2 stops13h 23m

$490

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Thu 10/30

6:21 pm-1:05 am

3 stops31h 44m

Guayaquil Jose Joaquin de Olmedo

Thu 11/6

10:25 am-9:12 pm

2 stops34h 47m

$596

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Thu 11/27

6:30 am-1:34 pm

2 stops31h 04m

Guayaquil Jose Joaquin de Olmedo

Sun 12/7

12:20 pm-10:29 pm

2 stops34h 09m

$636

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Mon 9/29

9:38 pm-8:35 am

3 stops35h 57m

Guayaquil Jose Joaquin de Olmedo

Tue 10/21

4:15 am-7:37 am

3 stops26h 22m

$638

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Mon 2/16

4:40 pm-11:18 am

2 stops42h 38m

Guayaquil Jose Joaquin de Olmedo

Sun 3/1

12:20 pm-10:12 pm

2 stops33h 52m

$662

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Mon 9/29

10:32 am-2:05 am

2 stops40h 33m

Guayaquil Jose Joaquin de Olmedo

Mon 10/20

3:15 am-9:44 am

2 stops29h 29m

$669

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Mon 9/29

6:00 am-2:05 am

2 stops45h 05m

Guayaquil Jose Joaquin de Olmedo

Thu 10/23

3:15 am-9:30 am

2 stops29h 15m

$678

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Fri 11/28

6:20 am-11:18 am

2 stops28h 58m

Guayaquil Jose Joaquin de Olmedo

Sun 12/7

2:35 pm-10:29 pm

2 stops31h 54m

$683

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Fri 10/31

6:48 pm-9:15 am

3 stops39h 27m

$347

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Mon 12/15

6:45 am-11:45 pm

1 stop17h 00m

$389

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 13 results
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Best time to book a flight from Columbus to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to Guayaquil

What is the cheapest month to book a flight from Columbus Airport to Guayaquil?

Currently, April is the cheapest month in which you can book a flight from Columbus Airport to Guayaquil (average of $440). Flying from Columbus Airport to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated September 17, 2025.
Read reviews from past customers who have flown American Airlines from Columbus Airport to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Entertainment

6.9

Food

6.4

Overall

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Entertainment

6.9

Food

6.4

Overall

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Columbus to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from Columbus?

    If you book a flight to Guayaquil from Columbus, you will be flying to Jose Joaquin de Olmedo, which is the city’s only airport. Guayaquil Jose Joaquin de Olmedo (GYE) is located 2.5 mi from the center of Guayaquil. There are 0 flights from Columbus to Jose Joaquin de Olmedo per day from 1 airline.

  • How long is the flight from Columbus Airport to Guayaquil?

    For as low as $636, United Airlines can have you in Guayaquil from Columbus Airport in 31h 04m. The distance between Columbus Airport and Guayaquil is about 2917 mi.

  • What is the cheapest airline to fly from Columbus Airport to Guayaquil round-trip?

    American Airlines, at $655, was found to be the cheapest airline from Columbus Airport to Guayaquil.. American Airlines is 17% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Columbus to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Columbus to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Guayaquil.

  • Can I find deals for business class flights from Columbus to Guayaquil?

    Yes. Cheapflights offers flight deals from Columbus to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus Airport to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from Columbus Airport to Guayaquil (average of $440). Flying from Columbus Airport to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Columbus to Guayaquil

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Columbus to Quito flights

Top airline flying from Columbus to Guayaquil

Discover the top airline that operate flights from Columbus to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$655Average$825FlexibilityNo cancel feeOn-time71%

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