$346+ Cheap flights from Columbus (CMH) to Guayaquil (GYE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — GYE
Oct 24 — Oct 311
Round-trip
1 adult, Economy
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Find cheap flights from Columbus to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbus to Guayaquil
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Best
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One-way
Cheapest flights from Columbus to GuayaquilExplore the most affordable flight options available from Columbus to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
Explore the most affordable flight options available from Columbus to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
This Ovago deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:15 am -
2 stops18h 40m
Sat 11/146:38 pm -
2 stops15h 17m
Deal found 9/23![Copa Airlines logo]()
$821
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:00 am -
2 stops17h 16m
Sat 11/146:00 am -
1 stop17h 59m
Deal found 9/23![American Airlines logo]()
$888
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:40 am -
1 stop8h 49m
Thu 10/222:29 pm -
1 stop9h 08m
Deal found 9/21![American Airlines logo]()
$911
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/286:15 am -
2 stops17h 26m
Thu 12/3112:22 pm -
2 stops27h 27m
Deal found 9/21![United Airlines logo]()
$1,058
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/246:15 am -
2 stops14h 42m
Thu 12/318:25 am -
2 stops31h 24m
Deal found 9/21![United Airlines logo]()
$1,104
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:15 am -
2 stops17h 25m
Sat 11/142:47 pm -
3 stops22h 23m
Deal found 9/23![United Airlines logo]()
$1,141
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:15 am -
2 stops14h 42m
Thu 12/3112:22 pm -
2 stops27h 27m
Deal found 9/21![United Airlines logo]()
$1,145
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/285:40 am -
2 stops32h 50m
Thu 12/313:30 pm -
1 stop30h 20m
Deal found 9/21![American Airlines logo]()
$1,155
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:15 am -
2 stops17h 26m
Thu 12/318:25 am -
2 stops31h 24m
Deal found 9/21![United Airlines logo]()
$1,157
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/246:38 pm -
1 stop29h 17m
Thu 12/313:30 pm -
2 stops19h 18m
Deal found 9/21![American Airlines logo]()
$1,227
Best flights from Columbus to GuayaquilDiscover carefully curated flight deals from Columbus to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
Discover carefully curated flight deals from Columbus to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/611:55 am -
2 stops10h 38m
Sat 3/133:30 pm -
2 stops17h 13m
Deal found 9/22![American Airlines logo]()
$839
This LATAM Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/255:30 pm -
1 stop14h 32m
Wed 1/275:00 pm -
1 stop18h 41m
Deal found 9/19![LATAM Airlines logo]()
$951
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/259:06 am -
2 stops14h 37m
Wed 1/2712:22 pm -
2 stops35h 20m
Deal found 9/22![United Airlines logo]()
$988
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:00 am -
2 stops17h 16m
Sat 11/146:00 am -
1 stop17h 59m
Deal found 9/23![American Airlines logo]()
$888
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:15 am -
2 stops17h 25m
Sat 11/142:47 pm -
3 stops22h 23m
Deal found 9/23![United Airlines logo]()
$1,141
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:52 am -
2 stops12h 47m
Sat 10/106:00 am -
1 stop17h 37m
Deal found 9/23![American Airlines logo]()
$1,218
Last-minute flights from Columbus to GuayaquilDiscover last-minute flight deals from Columbus to Guayaquil. Data last updated September 24, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to Guayaquil. Data last updated September 24, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:40 am -
1 stop8h 49m
Thu 10/222:29 pm -
1 stop9h 08m
Deal found 9/21![American Airlines logo]()
$911
One-way flights from Columbus to GuayaquilSearch for one-way flight options from Columbus to Guayaquil. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
Search for one-way flight options from Columbus to Guayaquil. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:44 pm -
3 stops30h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/209:09 am -
3 stops41h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$473
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:26 am -
1 stop16h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![American Airlines logo]()
$485
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:46 pm -
2 stops18h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![American Airlines logo]()
$702
Find flight deals from Columbus to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from Columbus (CMH) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 24, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $821 (Ovago) |
One-way from | $346 (Kiwi.com) |
Popular in | October |
Cheapest in | April |
Average price | $780 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
Use the filters below to find and compare flights from Columbus Airport to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusGuayaquil
CMH Columbus - GYE Guayaquil Jose Joaquin de Olmedo
CMHGYE
Columbus
Sun 11/1
7:44 pm-2:15 am
3 stops30h 31m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$346
Quickest round-trip
ColumbusGuayaquil
CMH Columbus - GYE Guayaquil Jose Joaquin de Olmedo
CMHGYE
Columbus
Sun 11/1
6:10 am-11:16 pm
2 stops17h 06m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$485
ColumbusGuayaquil
CMH Columbus - GYE Guayaquil Jose Joaquin de Olmedo
CMHGYE
Columbus
Sun 12/20
9:09 am-2:15 am
3 stops41h 06m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$527
ColumbusGuayaquil
CMH Columbus - GYE Guayaquil Jose Joaquin de Olmedo
CMHGYE
Columbus
Sun 12/20
7:46 pm-2:30 pm
2 stops18h 44m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$702
ColumbusGuayaquil
CMH Columbus - GYE Guayaquil Jose Joaquin de Olmedo
CMHGYE
Columbus
Sat 3/6
11:55 am-10:33 pm
2 stops10h 38m
Guayaquil Jose Joaquin de Olmedo
Sat 3/13
3:30 pm-8:43 am
2 stops17h 13m
$839
ColumbusGuayaquil
CMH Columbus - GYE Guayaquil Jose Joaquin de Olmedo
CMHGYE
Columbus
Sat 11/7
6:00 am-11:16 pm
2 stops17h 16m
Guayaquil Jose Joaquin de Olmedo
Sat 11/14
6:00 am-11:59 pm
1 stop17h 59m
$888
ColumbusGuayaquil
CMH Columbus - GYE Guayaquil Jose Joaquin de Olmedo
CMHGYE
Columbus
Mon 1/25
5:30 pm-8:02 am
1 stop14h 32m
Guayaquil Jose Joaquin de Olmedo
Wed 1/27
5:00 pm-11:41 am
1 stop18h 41m
$951
ColumbusGuayaquil
CMH Columbus - GYE Guayaquil Jose Joaquin de Olmedo
CMHGYE
Columbus
Mon 1/25
9:06 am-11:43 pm
2 stops14h 37m
Guayaquil Jose Joaquin de Olmedo
Wed 1/27
12:22 pm-11:42 pm
2 stops35h 20m
$988
ColumbusGuayaquil
CMH Columbus - GYE Guayaquil Jose Joaquin de Olmedo
CMHGYE
Columbus
Sat 11/7
6:15 am-11:40 pm
2 stops17h 25m
Guayaquil Jose Joaquin de Olmedo
Sat 11/14
2:47 pm-1:10 pm
3 stops22h 23m
$1,141
ColumbusGuayaquil
CMH Columbus - GYE Guayaquil Jose Joaquin de Olmedo
CMHGYE
Columbus
Tue 10/6
10:52 am-10:39 pm
2 stops12h 47m
Guayaquil Jose Joaquin de Olmedo
Sat 10/10
6:00 am-12:37 am
1 stop17h 37m
$1,218
Sorted by cheapest first
Compare providers for flights from Columbus to Guayaquil
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbus to Guayaquil in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Columbus Airport-Guayaquil flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Columbus Airport-Guayaquil flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Columbus Airport-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Columbus Airport-Guayaquil flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbus Airport-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Columbus to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Columbus with our price prediction graph.
CMH-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus Airport to Guayaquil
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated September 24, 2026.
Read reviews from past customers who have flown American Airlines from Columbus Airport to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Boarding
7.4
Crew
7.9
Overall
7.0
Food
6.4
Comfort
7.2
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Entertainment
6.8
Boarding
7.4
Crew
7.9
Overall
7.0
Food
6.4
Comfort
7.2
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Columbus to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Guayaquil by adding a car rental and/or hotel reservation to your travel itinerary.
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 24, 2026.
Columbus and Guayaquil flights
Browse other Columbus and Guayaquil flight options. Last updated on September 24, 2026.
Other flights from Columbus
Browse through other flights departing from Columbus. Flights are based on user searches made on Cheapflights and were last updated on September 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Columbus to Guayaquil
Discover the top airline that operate flights from Columbus to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$663 | Average$889 | FlexibilityNo cancel fee | On-time71% |