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Guayaquil

$395+ Cheap flights from Columbus (CMH) to Guayaquil (GYE)

CMH — GYE
Nov 25 — Dec 21
Wed 11/25
Wed 12/2
1 adult, Economy
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Cheap flight deals from Columbus to Guayaquil

Cheapest flights from Columbus to Guayaquil

Mon 11/99:30 am -
2 stops13h 46m
Wed 11/186:00 am -
2 stops15h 21m
Deal found 10/23$731
Sat 11/76:18 pm -
1 stop13h 49m
Mon 11/235:00 pm -
1 stop18h 49m
Deal found 10/23$752
Mon 11/96:15 am -
2 stops17h 25m
Wed 11/1812:25 pm -
3 stops24h 45m
Deal found 10/23$1,263
Sat 11/76:15 am -
2 stops28h 00m
Mon 11/2312:25 pm -
3 stops24h 45m
Deal found 10/23$1,292
Sun 12/276:15 am -
2 stops14h 42m
Sat 1/29:15 pm -
2 stops26h 34m
Deal found 10/24$1,927
Sun 12/207:05 am -
2 stops25h 52m
Sat 1/25:38 pm -
2 stops18h 37m
Deal found 10/23$2,696
Sun 12/205:10 am -
2 stops18h 31m
Sat 1/26:34 pm -
2 stops15h 15m
Deal found 10/25$2,744

Find flight deals from Columbus to Guayaquil

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$707
(LATAM Airlines)

One-way from

$395
(Kiwi.com)

Popular in

December

Cheapest in

March
Provider with most accurate pricing for Columbus-Guayaquil Jose Joaquin de Olmedo flight deals.
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Provider most trusted by Cheapflights users for Columbus-Guayaquil Jose Joaquin de Olmedo flights.
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From Columbus to Guayaquil Jose Joaquin de Olmedo
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One-way flight from Columbus to Guayaquil Jose Joaquin de Olmedo
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($89 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($27 potential savings vs. average RT price).
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Columbus Airport to Guayaquil that are best for you.

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Route

Depart

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Price

Cheapest round-trip

ColumbusGuayaquil

CMH Columbus - GYE Guayaquil Jose Joaquin de Olmedo

CMHGYE

Columbus

Sun 11/1

9:09 am-11:40 pm

2 stops14h 31m

Guayaquil Jose Joaquin de Olmedo

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$395
Quickest round-trip

ColumbusGuayaquil

CMH Columbus - GYE Guayaquil Jose Joaquin de Olmedo

CMHGYE

Columbus

Sun 11/1

5:00 am-2:34 pm

1 stop9h 34m

Guayaquil Jose Joaquin de Olmedo

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$472

ColumbusGuayaquil

CMH Columbus - GYE Guayaquil Jose Joaquin de Olmedo

CMHGYE

Columbus

Mon 4/5

5:30 pm-7:02 am

1 stop14h 32m

Guayaquil Jose Joaquin de Olmedo

Thu 4/15

4:00 pm-11:41 am

1 stop18h 41m

$707

ColumbusGuayaquil

CMH Columbus - GYE Guayaquil Jose Joaquin de Olmedo

CMHGYE

Columbus

Mon 11/9

7:16 pm-2:34 pm

1 stop19h 18m

Guayaquil Jose Joaquin de Olmedo

Wed 11/18

6:00 am-9:29 pm

1 stop15h 29m

$754

ColumbusGuayaquil

CMH Columbus - GYE Guayaquil Jose Joaquin de Olmedo

CMHGYE

Columbus

Sat 11/7

4:00 pm-8:07 am

2 stops16h 07m

Guayaquil Jose Joaquin de Olmedo

Mon 11/23

5:00 pm-11:49 am

1 stop18h 49m

$756

ColumbusGuayaquil

CMH Columbus - GYE Guayaquil Jose Joaquin de Olmedo

CMHGYE

Columbus

Mon 1/25

9:00 am-11:43 pm

2 stops14h 43m

Guayaquil Jose Joaquin de Olmedo

Wed 1/27

12:22 pm-11:44 pm

2 stops35h 22m

$1,048

ColumbusGuayaquil

CMH Columbus - GYE Guayaquil Jose Joaquin de Olmedo

CMHGYE

Columbus

Mon 1/25

5:30 pm-8:02 am

1 stop14h 32m

Guayaquil Jose Joaquin de Olmedo

Wed 1/27

5:00 pm-11:41 am

1 stop18h 41m

$1,106

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/22

Sorted by cheapest first

Compare providers for flights from Columbus to Guayaquil

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbus to Guayaquil in October.
ProviderPrice AccuracyTrust Score*
OvagoPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Columbus Airport-Guayaquil flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Columbus Airport-Guayaquil flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Columbus Airport-Guayaquil flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Columbus Airport-Guayaquil flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbus Airport-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Columbus to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Columbus with our price prediction graph.
Estimated round-trip price

Reviews of airlines servicing Guayaquil

Read reviews from past customers who have flown American Airlines from Columbus Airport to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.0
Good
12,190 reviews

Comfort

7.1

Food

6.4

Boarding

7.4

Overall

7.0

Entertainment

6.8

Crew

7.9

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go
American Airlines
7.0
Good
12,190 reviews
American Airlines
7.0
Good
12,190 reviews

Comfort

7.1

Food

6.4

Boarding

7.4

Overall

7.0

Entertainment

6.8

Crew

7.9

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go

Related info for your journey

  • What airport do you fly into for flights to Guayaquil from Columbus?

    If you book a flight to Guayaquil from Columbus, you will be flying to Jose Joaquin de Olmedo, which is the city’s only airport. Guayaquil Jose Joaquin de Olmedo (GYE) is located 2.5 mi from the center of Guayaquil. There are 0 flights from Columbus to Jose Joaquin de Olmedo per day from 1 airline.

  • How long is the flight from Columbus Airport to Guayaquil?

    For as low as $756, American Airlines can have you in Guayaquil from Columbus Airport in 16h 07m. The distance between Columbus Airport and Guayaquil is about 2917 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Columbus Airport to Guayaquil round-trip?

    American Airlines, at $663, was found to be the cheapest airline from Columbus Airport to Guayaquil.. American Airlines is 21% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Columbus to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Columbus to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Guayaquil.

  • Can I find deals for business class flights from Columbus to Guayaquil?

    Yes. Cheapflights offers flight deals from Columbus to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Columbus to Guayaquil

Columbus to Quito flights

Top airline flying from Columbus to Guayaquil

AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$663Average$887FlexibilityNo cancel feeOn-time71%

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