$122+ Cheap flights from Jacksonville (JAX) to Guayaquil (GYE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — GYE
Mar 30 — Apr 61
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Jacksonville to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Jacksonville to Guayaquil
Cheapest
Best
Last-minute
One-way
Cheapest flights from Jacksonville to GuayaquilExplore the most affordable flight options available from Jacksonville to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 28, 2026.
Explore the most affordable flight options available from Jacksonville to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 28, 2026.
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:19 pm
JAX
- GYE
2 stops18h 12m
American Airlines
Sat 5/162:31 pm
GYE
- JAX
1 stop8h 28m
American Airlines
Deal found 2/28![American Airlines logo]()
$299
This Avianca deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2111:12 am
JAX
- GYE
2 stops13h 18m
Multiple Airlines
Fri 4/248:00 pm
GYE
- JAX
1 stop13h 44m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$390
This KAYAK deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:42 pm
JAX
- GYE
2 stops19h 49m
GOL
Fri 4/242:31 pm
GYE
- JAX
2 stops21h 08m
GOL
Deal found 2/25![GOL logo]()
$413
This Priceline deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:10 am
JAX
- GYE
1 stop26h 35m
Multiple Airlines
Sat 5/164:00 pm
GYE
- JAX
1 stop17h 16m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$419
This Gurufare deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:19 pm
JAX
- GYE
2 stops18h 12m
GOL
Sat 5/162:31 pm
GYE
- JAX
2 stops21h 08m
GOL
Deal found 2/28![GOL logo]()
$452
This Avianca deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:43 am
JAX
- GYE
1 stop21h 12m
Multiple Airlines
Fri 3/64:05 pm
GYE
- JAX
1 stop17h 49m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$549
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/288:07 pm
JAX
- GYE
2 stops18h 23m
American Airlines
Fri 3/63:30 pm
GYE
- JAX
1 stop17h 33m
American Airlines
Deal found 2/24![American Airlines logo]()
$559
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:35 am
JAX
- GYE
2 stops18h 03m
United Airlines
Sat 4/1812:22 pm
GYE
- JAX
2 stops32h 42m
United Airlines
Deal found 2/25![United Airlines logo]()
$648
This LATAM Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/271:24 pm
JAX
- GYE
2 stops18h 24m
LATAM Airlines
Mon 3/24:57 pm
GYE
- JAX
2 stops15h 47m
LATAM Airlines
Deal found 2/24![LATAM Airlines logo]()
$901
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/289:20 am
JAX
- GYE
2 stops32h 13m
United Airlines
Mon 3/212:20 pm
GYE
- JAX
2 stops22h 23m
United Airlines
Deal found 2/27![United Airlines logo]()
$1,052
Best flights from Jacksonville to GuayaquilDiscover carefully curated flight deals from Jacksonville to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 28, 2026.
Discover carefully curated flight deals from Jacksonville to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 28, 2026.
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:19 pm
JAX
- GYE
2 stops18h 12m
American Airlines
Sat 5/162:31 pm
GYE
- JAX
1 stop8h 28m
American Airlines
Deal found 2/28![American Airlines logo]()
$299
This Avianca deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2111:12 am
JAX
- GYE
2 stops13h 18m
Multiple Airlines
Fri 4/248:00 pm
GYE
- JAX
1 stop13h 44m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$390
This KAYAK deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:42 pm
JAX
- GYE
2 stops19h 49m
GOL
Fri 4/242:31 pm
GYE
- JAX
2 stops21h 08m
GOL
Deal found 2/25![GOL logo]()
$413
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:35 am
JAX
- GYE
2 stops18h 03m
United Airlines
Sat 4/1812:22 pm
GYE
- JAX
2 stops32h 42m
United Airlines
Deal found 2/25![United Airlines logo]()
$648
This Priceline deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:10 am
JAX
- GYE
1 stop26h 35m
Multiple Airlines
Sat 5/164:00 pm
GYE
- JAX
1 stop17h 16m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$419
This Gurufare deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:19 pm
JAX
- GYE
2 stops18h 12m
GOL
Sat 5/162:31 pm
GYE
- JAX
2 stops21h 08m
GOL
Deal found 2/28![GOL logo]()
$452
Last-minute flights from Jacksonville to GuayaquilDiscover last-minute flight deals from Jacksonville to Guayaquil. Data last updated February 28, 2026 and is based on user searches.
Discover last-minute flight deals from Jacksonville to Guayaquil. Data last updated February 28, 2026 and is based on user searches.
This LATAM Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/271:24 pm
JAX
- GYE
2 stops18h 24m
LATAM Airlines
Mon 3/24:57 pm
GYE
- JAX
2 stops15h 47m
LATAM Airlines
Deal found 2/24![LATAM Airlines logo]()
$901
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/277:45 am
JAX
- GYE
2 stops15h 57m
United Airlines
Mon 3/212:20 pm
GYE
- JAX
2 stops22h 29m
United Airlines
Deal found 2/25![United Airlines logo]()
$1,126
This Avianca deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:43 am
JAX
- GYE
1 stop21h 12m
Multiple Airlines
Fri 3/64:05 pm
GYE
- JAX
1 stop17h 49m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$549
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:09 pm
JAX
- GYE
2 stops20h 21m
American Airlines
Fri 3/63:30 pm
GYE
- JAX
2 stops17h 21m
American Airlines
Deal found 2/24![American Airlines logo]()
$559
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/289:20 am
JAX
- GYE
2 stops32h 13m
United Airlines
Mon 3/212:20 pm
GYE
- JAX
2 stops22h 23m
United Airlines
Deal found 2/27![United Airlines logo]()
$1,052
One-way flights from Jacksonville to GuayaquilSearch for one-way flight options from Jacksonville to Guayaquil. Find affordable one-way fares based on user searches. Data last updated February 28, 2026.
Search for one-way flight options from Jacksonville to Guayaquil. Find affordable one-way fares based on user searches. Data last updated February 28, 2026.
This American Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:00 am
JAX
- GYE
1 stop16h 12m
American Airlines
Deal found 2/25![American Airlines logo]()
$122
This American Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:05 pm
JAX
- GYE
1 stop26h 07m
American Airlines
Deal found 2/25![American Airlines logo]()
$128
This Ovago deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:07 pm
JAX
- GYE
2 stops26h 05m
GOL
Deal found 2/24![GOL logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:18 pm
JAX
- GYE
2 stops34h 17m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$210
This oojo deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:05 am
JAX
- GYE
1 stop29h 35m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:37 am
JAX
- GYE
3 stops58h 17m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$282
Find flight deals from Jacksonville to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from Jacksonville (JAX) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $299 (American Airlines) |
One-way from | $122 (American Airlines) |
Popular in | July |
Cheapest in | September |
Average price | $997 |
Cheapflights Fare Finder
Customize your flight search to find flights from Jacksonville to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 28, 2026.
Use the filters below to find and compare flights from Jacksonville to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
JacksonvilleGuayaquil
JAX - GYE
JAXGYE
Jacksonville
Sat 5/9
8:19 pm-1:31 pm
2 stops18h 12m
Guayaquil Jose Joaquin de Olmedo
Sat 5/16
2:31 pm-11:59 pm
1 stop8h 28m
$299
JacksonvilleGuayaquil
JAX - GYE
JAXGYE
Jacksonville
Tue 4/21
11:12 am-11:30 pm
2 stops13h 18m
Guayaquil Jose Joaquin de Olmedo
Fri 4/24
8:00 pm-10:44 am
1 stop13h 44m
$390
JacksonvilleGuayaquil
JAX - GYE
JAXGYE
Jacksonville
Tue 4/21
6:42 pm-1:31 pm
2 stops19h 49m
Guayaquil Jose Joaquin de Olmedo
Fri 4/24
2:31 pm-12:39 pm
2 stops21h 08m
$413
JacksonvilleGuayaquil
JAX - GYE
JAXGYE
Jacksonville
Sat 5/9
6:10 am-7:45 am
1 stop26h 35m
Guayaquil Jose Joaquin de Olmedo
Sat 5/16
4:00 pm-10:16 am
1 stop17h 16m
$419
JacksonvilleGuayaquil
JAX - GYE
JAXGYE
Jacksonville
Sat 5/9
8:19 pm-1:31 pm
2 stops18h 12m
Guayaquil Jose Joaquin de Olmedo
Sat 5/16
2:31 pm-12:39 pm
2 stops21h 08m
$452
JacksonvilleGuayaquil
JAX - GYE
JAXGYE
Jacksonville
Sat 4/11
6:35 am-11:38 pm
2 stops18h 03m
Guayaquil Jose Joaquin de Olmedo
Sat 4/18
12:22 pm-10:04 pm
2 stops32h 42m
$648
JacksonvilleGuayaquil
JAX - GYE
JAXGYE
Jacksonville
Tue 4/7
6:42 pm-1:31 pm
2 stops19h 49m
$125
JacksonvilleGuayaquil
JAX - GYE
JAXGYE
Jacksonville
Mon 4/6
8:05 pm-9:12 pm
1 stop26h 07m
$128
JacksonvilleGuayaquil
JAX - GYE
JAXGYE
Jacksonville
Mon 4/6
8:07 pm-9:12 pm
2 stops26h 05m
$206
JacksonvilleGuayaquil
JAX - GYE
JAXGYE
Jacksonville
Mon 4/6
8:18 pm-11:38 pm
3 stops28h 20m
$221
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Jacksonville to Guayaquil
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Jacksonville to Guayaquil in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars |
- Most accurate provider: When it comes to deals on Jacksonville-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Jacksonville-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Jacksonville-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Jacksonville-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Jacksonville-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Jacksonville to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Jacksonville with our price prediction graph.
JAX-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated February 28, 2026.
Read reviews from past customers who have flown American Airlines from Jacksonville to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.9
Boarding
7.5
Overall
7.2
Food
6.4
Comfort
7.2
Crew
8.0
Reviews
1 / 20
4.0
OkaySusie,Jan 2026
TPA - CLT
Entertainment
6.9
Boarding
7.5
Overall
7.2
Food
6.4
Comfort
7.2
Crew
8.0
Reviews
1 / 20
4.0
OkaySusie,Jan 2026
TPA - CLT
Related info for your journey
Find useful and relevant information for your journey from Jacksonville to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Guayaquil flight routes
Other flight options
Other flights from Jacksonville
Popular flights
Alternative routes for Jacksonville to Guayaquil
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Guayaquil by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Jacksonville to Guayaquil by cabin class
Find flights from Jacksonville to Guayaquil, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 28, 2026.
Jacksonville and Guayaquil flights
Browse other Jacksonville and Guayaquil flight options. Last updated on February 28, 2026.
Other flights from Jacksonville
Browse through other flights departing from Jacksonville. Flights are based on user searches made on Cheapflights and were last updated on February 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Jacksonville to Guayaquil
Discover the top airline that operate flights from Jacksonville to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$535 | Average$689 | FlexibilityNo cancel fee | On-time71% |