$691+ Cheap flights from Greenville (GSP) to Guayaquil (GYE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — GYE
Nov 7 — Nov 141
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to Guayaquil
Cheapest
Best
Last-minute
Cheapest flights from Greenville to GuayaquilExplore the most affordable flight options available from Greenville to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 8, 2026.
Explore the most affordable flight options available from Greenville to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 8, 2026.
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:55 am -
2 stops15h 21m
Sun 11/156:00 am -
1 stop17h 52m
Deal found 10/5![American Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:58 pm -
2 stops20h 36m
Mon 11/163:34 pm -
2 stops21h 37m
Deal found 10/5![American Airlines logo]()
$716
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:05 am -
2 stops17h 34m
Sat 10/246:00 am -
1 stop15h 52m
Deal found 10/7![American Airlines logo]()
$736
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:55 am -
2 stops15h 31m
Thu 11/266:00 am -
2 stops30h 07m
Deal found 10/5![American Airlines logo]()
$749
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:26 am -
3 stops13h 14m
Thu 11/2612:25 pm -
2 stops21h 27m
Deal found 10/5![United Airlines logo]()
$7,964
Best flights from Greenville to GuayaquilDiscover carefully curated flight deals from Greenville to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 8, 2026.
Discover carefully curated flight deals from Greenville to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 8, 2026.
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:55 am -
2 stops15h 21m
Sun 11/156:00 am -
1 stop17h 52m
Deal found 10/5![American Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:55 am -
2 stops15h 31m
Thu 11/266:00 am -
1 stop13h 32m
Deal found 10/5![American Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:12 pm -
1 stop18h 22m
Mon 11/166:00 am -
1 stop17h 52m
Deal found 10/5![American Airlines logo]()
$712
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/278:28 pm -
2 stops18h 10m
Sat 3/272:40 pm -
2 stops20h 34m
Deal found 10/7![American Airlines logo]()
$765
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:26 am -
3 stops13h 14m
Thu 11/2612:25 pm -
2 stops21h 27m
Deal found 10/5![United Airlines logo]()
$7,964
Last-minute flights from Greenville to GuayaquilDiscover last-minute flight deals from Greenville to Guayaquil. Data last updated October 8, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to Guayaquil. Data last updated October 8, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:05 am -
2 stops17h 34m
Sat 10/246:00 am -
1 stop15h 52m
Deal found 10/7![American Airlines logo]()
$736
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:55 am -
2 stops15h 21m
Sun 11/156:00 am -
1 stop17h 52m
Deal found 10/5![American Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:58 pm -
2 stops20h 36m
Mon 11/163:34 pm -
2 stops21h 37m
Deal found 10/5![American Airlines logo]()
$716
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:55 am -
2 stops15h 31m
Thu 11/266:00 am -
2 stops30h 07m
Deal found 10/5![American Airlines logo]()
$749
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:26 am -
3 stops13h 14m
Thu 11/2612:25 pm -
2 stops21h 27m
Deal found 10/5![United Airlines logo]()
$7,964
Find flight deals from Greenville to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 8, 2026.
Most accurate provider | Expedia 1 star |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $691 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 8, 2026.
Use the filters below to find and compare flights from Greenville to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleGuayaquil
GSP Greenville - GYE Guayaquil Jose Joaquin de Olmedo
GSPGYE
Greenville
Thu 11/12
7:55 am-11:16 pm
2 stops15h 21m
Guayaquil Jose Joaquin de Olmedo
Sun 11/15
6:00 am-11:52 pm
1 stop17h 52m
$691
Quickest round-trip
GreenvilleGuayaquil
GSP Greenville - GYE Guayaquil Jose Joaquin de Olmedo
GSPGYE
Greenville
Thu 11/19
7:55 am-11:26 pm
2 stops15h 31m
Guayaquil Jose Joaquin de Olmedo
Thu 11/26
6:00 am-7:32 pm
1 stop13h 32m
$691
GreenvilleGuayaquil
GSP Greenville - GYE Guayaquil Jose Joaquin de Olmedo
GSPGYE
Greenville
Fri 11/13
8:12 pm-2:34 pm
1 stop18h 22m
Guayaquil Jose Joaquin de Olmedo
Mon 11/16
6:00 am-11:52 pm
1 stop17h 52m
$712
GreenvilleGuayaquil
GSP Greenville - GYE Guayaquil Jose Joaquin de Olmedo
GSPGYE
Greenville
Sat 2/27
8:28 pm-2:38 pm
2 stops18h 10m
Guayaquil Jose Joaquin de Olmedo
Sat 3/27
2:40 pm-12:14 pm
2 stops20h 34m
$765
GreenvilleGuayaquil
GSP Greenville - GYE Guayaquil Jose Joaquin de Olmedo
GSPGYE
Greenville
Thu 11/19
10:26 am-11:40 pm
3 stops13h 14m
Guayaquil Jose Joaquin de Olmedo
Thu 11/26
12:25 pm-9:52 am
2 stops21h 27m
$7,964
Sorted by cheapest first
- Most accurate provider: When it comes to deals on Greenville-Guayaquil flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Greenville-Guayaquil flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Greenville-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-Guayaquil flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Greenville with our price prediction graph.
GSP-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated October 8, 2026.
See what other customers who have flown with American Airlines from Greenville to Guayaquil have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Boarding
7.4
Crew
7.9
Comfort
7.2
Overall
7.0
Entertainment
6.8
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Food
6.4
Boarding
7.4
Crew
7.9
Comfort
7.2
Overall
7.0
Entertainment
6.8
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Greenville to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 8, 2026.
Greenville and Guayaquil flights
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Other flights from Greenville
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Popular flight searches
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Top airline flying from Greenville to Guayaquil
Discover the top airline that operate flights from Greenville to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$664 | Average$938 | FlexibilityNo cancel fee | On-time71% |