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Guatemala

$163+ Cheap flights from Mississippi to Guatemala

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — GUA
Nov 25 — Dec 21
Tue 11/25
Tue 12/2
1 adult, Economy
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Cheap flight deals from Mississippi to Guatemala

Keep the following information in mind while searching for Mississippi to Guatemala flight deals. Data was last updated October 26, 2025.

Round-trip from

$325
(Kiwi.com)

One-way from

$163
(Kiwi.com)

Popular in

November

Cheapest in

April

Average price

$504
From Mississippi to Guatemala
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One-way flight from Mississippi to Guatemala
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Highest demand for flights based on searches. 15% potential increase in price ($140 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($40 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Mississippi to Guatemala

Cheapest flights from Mississippi to Guatemala
Explore the most affordable flight options available from Mississippi to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/91:22 pmMEM - GUA
2 stops24h 01mMultiple Airlines
Tue 12/163:00 pmGUA - MEM
1 stop27h 47mMultiple Airlines
Deal found 10/25$325
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:42 pmMEM - GUA
1 stop18h 23mSpirit Airlines
Mon 12/1512:20 pmGUA - MEM
1 stop28h 56mSpirit Airlines
Deal found 10/23$350
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/89:17 pmMEM - GUA
2 stops40h 06mMultiple Airlines
Mon 12/1512:20 pmGUA - MEM
1 stop28h 56mMultiple Airlines
Deal found 10/23$381
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:42 pmMEM - GUA
1 stop15h 41mSpirit Airlines
Tue 12/163:00 pmGUA - MEM
1 stop27h 47mSpirit Airlines
Deal found 10/25$382
This Priceline deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/157:42 pmMEM - GUA
1 stop15h 41mSpirit Airlines
Fri 1/212:20 pmGUA - MEM
1 stop7h 02mSpirit Airlines
Deal found 10/26$530
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/268:17 amMEM - GUA
2 stops48h 18mMultiple Airlines
Wed 10/2912:27 pmGUA - MEM
1 stop18h 00mMultiple Airlines
Deal found 10/26$539
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/237:55 pmGPT - GUA
1 stop15h 24mMultiple Airlines
Sun 11/3012:16 pmGUA - GPT
1 stop6h 59mMultiple Airlines
Deal found 10/26$610
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/235:15 pmGPT - GUA
1 stop26h 24mUnited Airlines
Sat 11/292:10 amGUA - GPT
1 stop9h 07mUnited Airlines
Deal found 10/26$809
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2312:09 pmGPT - GUA
1 stop10h 34mAmerican Airlines
Sun 11/306:36 amGUA - GPT
1 stop29h 03mAmerican Airlines
Deal found 10/26$864

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Guatemala that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 26, 2025.
Use the filters below to find and compare flights from Mississippi to Guatemala that are best for you.

Fly from

Mississippi

Fly to

Guatemala

Route

Depart

Return

Price

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

Mon 1/5

8:17 pm-11:25 am

1 stop15h 08m

Guatemala City La Aurora

Fri 2/6

1:22 pm-5:22 pm

1 stop28h 00m

$318

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

Tue 12/9

1:22 pm-1:23 pm

2 stops24h 01m

Guatemala City La Aurora

Tue 12/16

3:00 pm-6:47 pm

1 stop27h 47m

$325

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

Mon 12/8

7:42 pm-2:05 pm

1 stop18h 23m

Guatemala City La Aurora

Mon 12/15

12:20 pm-5:16 pm

1 stop28h 56m

$350

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

Mon 12/8

9:17 pm-1:23 pm

2 stops40h 06m

Guatemala City La Aurora

Mon 12/15

12:20 pm-5:16 pm

1 stop28h 56m

$381

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

Tue 12/9

7:42 pm-11:23 am

1 stop15h 41m

Guatemala City La Aurora

Tue 12/16

1:39 pm-6:47 pm

3 stops29h 08m

$409

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

Mon 1/5

8:58 pm-7:41 am

3 stops34h 43m

Guatemala City La Aurora

Fri 2/6

1:22 pm-3:14 pm

3 stops25h 52m

$431

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

Tue 1/13

4:19 pm-11:16 am

1 stop18h 57m

Guatemala City La Aurora

Tue 1/20

12:11 pm-3:14 pm

1 stop27h 03m

$461

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

Tue 1/13

5:49 pm-1:13 pm

2 stops19h 24m

Guatemala City La Aurora

Tue 1/20

7:00 am-10:51 pm

2 stops15h 51m

$520

GulfportGuatemala City

GPT - GUA

GPTGUA

Gulfport Biloxi Regional

Tue 3/10

6:00 am-11:45 am

1 stop6h 45m

Guatemala City La Aurora

Thu 3/12

1:10 pm-10:09 pm

1 stop7h 59m

$631

GulfportGuatemala City

GPT - GUA

GPTGUA

Gulfport Biloxi Regional

Sun 11/23

7:55 pm-1:50 pm

1 stop17h 55m

Guatemala City La Aurora

Sun 11/30

2:55 pm-6:11 pm

2 stops27h 16m

$631

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 20 results
1
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Best time to book a flight from Mississippi to Guatemala

Have a flexible travel schedule? Discover the best time to fly to Guatemala from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Guatemala
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Guatemala. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Guatemala?

    Airlines like Spirit Airlines, Delta, and United Airlines fly from Mississippi to Guatemala in about 6h 45m. The time it takes to get you to your destination can typically vary by up to 8h 23m. The distance from Mississippi to Guatemala is about 1097 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Mississippi to Guatemala one-way?

    $255 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on United Airlines and American Airlines, with prices starting from $323 and $354, respectively.

  • Can I find deals for flights from Mississippi to Guatemala that include hotel bookings?

    Yes. In addition to deals on Mississippi to Guatemala flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Guatemala?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Guatemala.

  • Can I find deals for business class flights from Mississippi to Guatemala?

    Yes. Cheapflights offers flight deals from Mississippi to Guatemala by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Mississippi to Guatemala

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to San Salvador flights
John F Kennedy Intl to San José flights
John F Kennedy Intl to Panama City flights
Los Angeles to Guatemala City flights
Newark to San José flights
John F Kennedy Intl to Guatemala City flights
Hobby to San Salvador flights
Newark to Panama City flights
Dulles Intl to San Salvador flights
John F Kennedy Intl to San Salvador flights
George Bush Intcntl to San Salvador flights
Los Angeles to San José flights
Dallas/Fort Worth to San Salvador flights
Newark to Guatemala City flights
O'Hare Intl to San José flights
Dulles Intl to Panama City flights
LaGuardia to San José flights
Newark to Liberia flights
John F Kennedy Intl to Liberia flights
Dulles Intl to San José flights
Hobby to San José flights
Dulles Intl to Guatemala City flights
O'Hare Intl to Panama City flights
LaGuardia to Panama City flights
Miami to Panama City flights
Newark to San Salvador flights
Miami to Managua flights
Ontario to San Salvador flights
Los Angeles to Panama City flights
Atlanta to San José flights
George Bush Intcntl to San José flights
Hobby to Panama City flights
Dallas/Fort Worth to San José flights
San Francisco to San José flights
Los Angeles to Liberia flights
Boston to San José flights
Miami to San Salvador flights
Baltimore to San Salvador flights
Boston to Liberia flights
Baltimore to San José flights
O'Hare Intl to Guatemala City flights
LaGuardia to San Salvador flights
San Francisco to Panama City flights
Baltimore to Panama City flights
Reagan-National to San Salvador flights
Reagan-National to San José flights
Atlanta to Panama City flights
O'Hare Intl to Liberia flights
Los Angeles to Philip S.W.Goldson flights
Denver to Liberia flights

Top airline flying from Mississippi to Guatemala

Discover the top airline that operate flights from Mississippi to Guatemala. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$497Average$733FlexibilityNo cancel feeOn-time69%

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