$349+ Cheap flights from St. Louis (STL) to Guatemala City (GUA)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GUA
Dec 9 — Dec 161
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Guatemala City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Guatemala City
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Cheapest flights from St. Louis to Guatemala CityExplore the most affordable flight options available from St. Louis to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
Explore the most affordable flight options available from St. Louis to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:54 pm -
2 stops24h 55m
Sat 1/232:27 pm -
1 stop9h 37m
Deal found 11/4![Multiple Airlines logo]()
$686
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:54 pm -
2 stops24h 55m
Sun 1/173:22 pm -
1 stop17h 32m
Deal found 11/4![Multiple Airlines logo]()
$687
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:20 pm -
1 stop18h 52m
Tue 12/292:27 pm -
1 stop10h 14m
Deal found 11/7![Frontier logo]()
$690
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:20 pm -
1 stop18h 52m
Sat 1/91:07 pm -
2 stops32h 30m
Deal found 11/7![Frontier logo]()
$717
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:20 pm -
1 stop18h 52m
Tue 12/292:12 pm -
2 stops25h 14m
Deal found 11/7![Multiple Airlines logo]()
$798
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/184:21 pm -
2 stops28h 28m
Sun 12/203:22 pm -
1 stop9h 19m
Deal found 11/8![Multiple Airlines logo]()
$809
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:15 pm -
1 stop16h 08m
Tue 11/101:06 pm -
1 stop10h 27m
Deal found 11/5![American Airlines logo]()
$819
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:15 pm -
1 stop16h 08m
Tue 11/174:12 pm -
1 stop23h 38m
Deal found 11/8![American Airlines logo]()
$820
Best flights from St. Louis to Guatemala CityDiscover carefully curated flight deals from St. Louis to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
Discover carefully curated flight deals from St. Louis to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/36:10 am -
1 stop9h 25m
Wed 3/102:48 pm -
1 stop7h 24m
Deal found 11/6![United Airlines logo]()
$695
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/256:15 am -
2 stops13h 24m
Wed 3/102:10 am -
2 stops12h 07m
Deal found 11/7![United Airlines logo]()
$800
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/65:00 am -
1 stop8h 46m
Wed 1/131:28 pm -
1 stop9h 52m
Deal found 11/5![United Airlines logo]()
$825
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/111:00 am -
1 stop11h 48m
Wed 2/32:10 am -
1 stop11h 56m
Deal found 11/4![United Airlines logo]()
$825
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/256:06 am -
1 stop16h 42m
Thu 1/282:10 am -
1 stop7h 21m
Deal found 11/5![United Airlines logo]()
$859
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/136:30 am -
1 stop16h 18m
Fri 3/191:10 am -
2 stops19h 03m
Deal found 11/4![United Airlines logo]()
$1,040
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:50 pm -
2 stops17h 36m
Fri 11/272:10 am -
1 stop7h 52m
Deal found 11/5![United Airlines logo]()
$1,049
Last-minute flights from St. Louis to Guatemala CityDiscover last-minute flight deals from St. Louis to Guatemala City. Data last updated November 9, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Guatemala City. Data last updated November 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:15 pm -
1 stop16h 08m
Tue 11/101:06 pm -
1 stop10h 27m
Deal found 11/5![American Airlines logo]()
$819
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:15 pm -
1 stop16h 08m
Tue 11/174:12 pm -
1 stop23h 38m
Deal found 11/8![American Airlines logo]()
$820
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:54 pm -
2 stops24h 55m
Sat 1/232:27 pm -
1 stop9h 37m
Deal found 11/4![Multiple Airlines logo]()
$686
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:54 pm -
2 stops24h 55m
Sun 1/173:22 pm -
1 stop17h 32m
Deal found 11/4![Multiple Airlines logo]()
$687
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/184:21 pm -
2 stops28h 28m
Sun 12/203:22 pm -
1 stop9h 19m
Deal found 11/8![Multiple Airlines logo]()
$809
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:20 pm -
1 stop18h 52m
Tue 12/292:27 pm -
1 stop10h 14m
Deal found 11/7![Frontier logo]()
$690
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:20 pm -
1 stop18h 52m
Sat 1/91:07 pm -
2 stops32h 30m
Deal found 11/7![Frontier logo]()
$717
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:20 pm -
1 stop18h 52m
Tue 12/292:12 pm -
2 stops25h 14m
Deal found 11/7![Multiple Airlines logo]()
$798
One-way flights from St. Louis to Guatemala CitySearch for one-way flight options from St. Louis to Guatemala City. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
Search for one-way flight options from St. Louis to Guatemala City. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:54 pm -
2 stops24h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Multiple Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:20 pm -
3 stops26h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Multiple Airlines logo]()
$361
This FlightHub deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:30 am -
1 stop21h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Avianca logo]()
$438
This Arangrant deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arangrant is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/267:01 am -
1 stop7h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![GOL logo]()
$456
This BusinessClass deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/255:51 pm -
2 stops20h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![GOL logo]()
$463
This Arangrant deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arangrant is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/277:01 am -
2 stops13h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![GOL logo]()
$470
Find flight deals from St. Louis to Guatemala City
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $483 (Kiwi.com) |
One-way from | $349 (Kiwi.com) |
Popular in | December |
Cheapest in | February |
Average price | $731 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
Use the filters below to find and compare flights from St. Louis to Guatemala City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Sat 12/12
7:54 pm-8:49 pm
2 stops24h 55m
Guatemala City La Aurora
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$349
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Sun 12/6
6:20 pm-8:49 pm
3 stops26h 29m
Guatemala City La Aurora
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$361
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Tue 12/8
8:30 am-5:50 am
1 stop21h 20m
Guatemala City La Aurora
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$438
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Wed 1/27
7:01 am-8:59 pm
2 stops13h 58m
Guatemala City La Aurora
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$470
Quickest round-trip
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Mon 12/7
8:30 am-6:25 pm
2 stops9h 55m
Guatemala City La Aurora
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$495
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Mon 12/7
12:02 pm-1:02 pm
1 stop25h 00m
Guatemala City La Aurora
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$499
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Fri 1/29
8:47 am-11:21 pm
1 stop14h 34m
Guatemala City La Aurora
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$504
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Wed 3/3
6:10 am-3:35 pm
1 stop9h 25m
Guatemala City La Aurora
Wed 3/10
2:48 pm-10:12 pm
1 stop7h 24m
$695
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Thu 2/25
6:15 am-7:39 pm
2 stops13h 24m
Guatemala City La Aurora
Wed 3/10
2:10 am-2:17 pm
2 stops12h 07m
$800
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Wed 1/6
5:00 am-1:46 pm
1 stop8h 46m
Guatemala City La Aurora
Wed 1/13
1:28 pm-11:20 pm
1 stop9h 52m
$825
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from St. Louis to Guatemala City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Guatemala City in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on St. Louis-Guatemala City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Guatemala City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Guatemala City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Guatemala City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Guatemala City
Have a flexible travel schedule? Discover the best time to fly to Guatemala City from St. Louis with our price prediction graph.
STL-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Guatemala City
Prices
More
What is the cheapest month to book a flight from St. Louis to Guatemala City?
Currently, February is the cheapest month in which you can book a flight from St. Louis to Guatemala City (average of $457). Flying from St. Louis to Guatemala City in December is currently the most expensive (average of $975). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from St. Louis to Guatemala City?
Airfare is below average for this route at the moment.
St. Louis to Guatemala City flights typically cost between $669 and $817 in February.The cheapest round-trip price found within the last 5 days was $483 on Multiple Airlines (Feb 17-Feb 24).
What’s the top layover airport for flights from St. Louis to Guatemala City?
Share of 1-stop round-trip flights from St. Louis to Guatemala City chosen by Cheapflights users in the past 12 months, using the same layover each way.
Houston (IAH) – chosen by Cheapflights users on 67% of 1-stop itineraries from St. Louis to Guatemala City on Cheapflights.
What’s the cheapest layover airport for flights from St. Louis to Guatemala City?
Average round-trip fare for 1-stop flights from St. Louis to Guatemala City, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Dallas (DFW) is the most affordable 1-stop option, with an average round-trip price of $542.
What’s the fastest layover option from St. Louis to Guatemala City?
Shortest average travel time for 1-stop one-way flights from St. Louis to Guatemala City, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Houston (IAH) have the shortest average one-way travel time for 1-stop routes: 6h 20m.
Which airport typically offers the quickest layover for flights from St. Louis to Guatemala City?
Average layover duration for 1-stop one-way flights from St. Louis to Guatemala City, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Miami (MIA) offer the fastest connection on this route, with an average layover time of 1h 28m.
Reviews of airlines servicing Guatemala City
Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated November 9, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from St. Louis to Guatemala City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Food
7.2
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Crew
8.5
Food
7.2
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Crew
8.5
Food
7.2
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Crew
8.5
Food
7.2
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Guatemala City?
Book flights to Guatemala City if you plan to visit one of these locationsAntigua
Panajachel
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Complete your trip
Complete your trip to Guatemala City by adding a car rental and/or hotel reservation to your travel itinerary.
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Other flights to Guatemala City
Explore flights to Guatemala City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 9, 2026.
St. Louis and Guatemala City flights
Browse other St. Louis and Guatemala City flight options. Last updated on November 9, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on November 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from St. Louis to Guatemala City
Discover the top 3 airlines that operate flights from St. Louis to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$457 | Average$802 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$457 | Average$731 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$463 | Average$694 | FlexibilityNo cancel fee | On-time71% |