$286+ Cheap flights from St. Louis (STL) to Guatemala City (GUA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GUA
Jun 18 — Jun 251
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Guatemala City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Guatemala City
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to Guatemala CityExplore the most affordable flight options available from St. Louis to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 19, 2026.
Explore the most affordable flight options available from St. Louis to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 19, 2026.
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:33 am
STL
- GUA
1 stop6h 27m
American Airlines
Sat 9/2612:04 pm
GUA
- STL
1 stop8h 56m
American Airlines
Deal found 5/15![American Airlines logo]()
$489
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:08 pm
STL
- GUA
1 stop19h 37m
American Airlines
Sat 10/3112:04 pm
GUA
- STL
1 stop8h 56m
American Airlines
Deal found 5/19![American Airlines logo]()
$536
This Expedia deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:04 pm
STL
- GUA
1 stop15h 57m
Frontier
Thu 6/112:47 pm
GUA
- STL
1 stop8h 02m
Frontier
Deal found 5/18![Frontier logo]()
$548
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:06 am
STL
- GUA
2 stops13h 14m
American Airlines
Sat 9/2612:04 pm
GUA
- STL
1 stop8h 56m
American Airlines
Deal found 5/15![American Airlines logo]()
$557
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:00 am
STL
- GUA
1 stop15h 22m
American Airlines
Mon 8/172:25 pm
GUA
- STL
1 stop19h 20m
American Airlines
Deal found 5/15![American Airlines logo]()
$562
Best flights from St. Louis to Guatemala CityDiscover carefully curated flight deals from St. Louis to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 19, 2026.
Discover carefully curated flight deals from St. Louis to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 19, 2026.
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/192:12 pm
STL
- GUA
1 stop21h 48m
American Airlines
Sat 9/2612:04 pm
GUA
- STL
1 stop8h 56m
American Airlines
Deal found 5/15![American Airlines logo]()
$566
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:00 am
STL
- GUA
1 stop15h 40m
United Airlines
Mon 8/241:30 am
GUA
- STL
1 stop7h 40m
United Airlines
Deal found 5/19![United Airlines logo]()
$735
This Alaska Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/163:17 pm
STL
- GUA
2 stops16h 03m
Alaska Airlines
Sat 9/2611:20 am
GUA
- STL
3 stops28h 43m
Alaska Airlines
Deal found 5/16![Alaska Airlines logo]()
$901
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:00 am
STL
- GUA
1 stop16h 40m
United Airlines
Sun 6/710:50 pm
GUA
- STL
1 stop23h 45m
United Airlines
Deal found 5/15![United Airlines logo]()
$808
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:06 am
STL
- GUA
2 stops14h 29m
American Airlines
Mon 7/612:22 pm
GUA
- STL
1 stop10h 36m
American Airlines
Deal found 5/16![American Airlines logo]()
$872
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:33 pm
STL
- GUA
2 stops21h 57m
United Airlines
Sun 7/53:45 pm
GUA
- STL
2 stops15h 49m
United Airlines
Deal found 5/15![United Airlines logo]()
$824
Last-minute flights from St. Louis to Guatemala CityDiscover last-minute flight deals from St. Louis to Guatemala City. Data last updated May 19, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Guatemala City. Data last updated May 19, 2026 and is based on user searches.
This KAYAK deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:53 pm
STL
- GUA
2 stops18h 57m
GOL
Tue 6/22:25 pm
GUA
- STL
1 stop19h 09m
GOL
Deal found 5/16![GOL logo]()
$721
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2411:10 am
STL
- GUA
1 stop6h 27m
United Airlines
Wed 5/271:50 pm
GUA
- STL
1 stop7h 55m
United Airlines
Deal found 5/16![United Airlines logo]()
$739
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:00 am
STL
- GUA
2 stops14h 27m
American Airlines
Wed 6/310:08 am
GUA
- STL
2 stops13h 06m
American Airlines
Deal found 5/19![American Airlines logo]()
$713
This Expedia deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:04 pm
STL
- GUA
1 stop15h 57m
Frontier
Thu 6/112:47 pm
GUA
- STL
1 stop8h 02m
Frontier
Deal found 5/18![Frontier logo]()
$548
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/157:03 pm
STL
- GUA
2 stops17h 52m
Multiple Airlines
Sun 6/211:20 pm
GUA
- STL
1 stop24h 17m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$690
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:30 am
STL
- GUA
1 stop9h 15m
Multiple Airlines
Tue 7/78:15 pm
GUA
- STL
2 stops26h 44m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$711
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:30 am
STL
- GUA
1 stop9h 15m
Multiple Airlines
Wed 7/81:20 pm
GUA
- STL
2 stops24h 28m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$740
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/297:03 pm
STL
- GUA
2 stops17h 52m
Multiple Airlines
Mon 7/61:20 pm
GUA
- STL
1 stop24h 03m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$664
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/297:03 pm
STL
- GUA
2 stops17h 52m
Multiple Airlines
Tue 7/71:20 pm
GUA
- STL
1 stop24h 03m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$676
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:03 pm
STL
- GUA
2 stops17h 52m
Multiple Airlines
Mon 7/61:20 pm
GUA
- STL
1 stop24h 03m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$609
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:03 pm
STL
- GUA
2 stops17h 52m
Multiple Airlines
Tue 7/71:20 pm
GUA
- STL
1 stop24h 03m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$620
One-way flights from St. Louis to Guatemala CitySearch for one-way flight options from St. Louis to Guatemala City. Find affordable one-way fares based on user searches. Data last updated May 19, 2026.
Search for one-way flight options from St. Louis to Guatemala City. Find affordable one-way fares based on user searches. Data last updated May 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/157:03 pm
STL
- GUA
2 stops17h 52m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$286
This Orbitz deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:16 pm
STL
- GUA
1 stop19h 34m
Frontier
Deal found 5/16![Frontier logo]()
$345
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/157:20 pm
STL
- GUA
1 stop19h 03m
American Airlines
Deal found 5/16![American Airlines logo]()
$382
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:00 am
STL
- GUA
3 stops26h 15m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$511
Find flight deals from St. Louis to Guatemala City
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $489 (American Airlines) |
One-way from | $286 (Kiwi.com) |
Popular in | December |
Cheapest in | February |
Average price | $701 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 19, 2026.
Use the filters below to find and compare flights from St. Louis to Guatemala City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Sat 9/19
2:12 pm-11:00 am
1 stop21h 48m
Guatemala City La Aurora
Sat 9/26
12:04 pm-10:00 pm
1 stop8h 56m
$566
Quickest round-trip
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Sat 8/22
7:00 am-9:40 pm
1 stop15h 40m
Guatemala City La Aurora
Mon 8/24
1:30 am-10:10 am
1 stop7h 40m
$735
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Fri 5/29
6:00 am-9:40 pm
1 stop16h 40m
Guatemala City La Aurora
Sun 6/7
10:50 pm-11:35 pm
1 stop23h 45m
$808
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Thu 7/2
5:33 pm-2:30 pm
2 stops21h 57m
Guatemala City La Aurora
Sun 7/5
3:45 pm-8:34 am
2 stops15h 49m
$824
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Thu 7/2
6:06 am-7:35 pm
2 stops14h 29m
Guatemala City La Aurora
Mon 7/6
12:22 pm-11:58 pm
1 stop10h 36m
$872
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Wed 9/16
3:17 pm-6:20 am
2 stops16h 03m
Guatemala City La Aurora
Sat 9/26
11:20 am-5:03 pm
3 stops28h 43m
$901
Cheapest one-way
Quickest one-way
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Mon 6/15
7:03 pm-11:55 am
2 stops17h 52m
$286
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Sat 5/30
8:16 pm-2:50 pm
1 stop19h 34m
$345
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Mon 6/15
7:20 pm-1:23 pm
1 stop19h 03m
$382
Sorted by cheapest first
Compare providers for flights from St. Louis to Guatemala City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Guatemala City in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on St. Louis-Guatemala City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Guatemala City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Guatemala City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Guatemala City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Guatemala City
Have a flexible travel schedule? Discover the best time to fly to Guatemala City from St. Louis with our price prediction graph.
STL-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Guatemala City
Prices
More
What is the cheapest month to book a flight from St. Louis to Guatemala City?
Currently, February is the cheapest month in which you can book a flight from St. Louis to Guatemala City (average of $475). Flying from St. Louis to Guatemala City in December is currently the most expensive (average of $889). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from St. Louis to Guatemala City?
What’s the top layover airport for flights from St. Louis to Guatemala City?
Share of 1-stop round-trip flights from St. Louis to Guatemala City chosen by Cheapflights users in the past 12 months, using the same layover each way.
Houston (IAH) – chosen by Cheapflights users on 71% of 1-stop itineraries from St. Louis to Guatemala City on Cheapflights.
What’s the cheapest layover airport for flights from St. Louis to Guatemala City?
Average round-trip fare for 1-stop flights from St. Louis to Guatemala City, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Dallas (DFW) is the most affordable 1-stop option, with an average round-trip price of $542.
What’s the fastest layover option from St. Louis to Guatemala City?
Shortest average travel time for 1-stop one-way flights from St. Louis to Guatemala City, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Houston (IAH) have the shortest average one-way travel time for 1-stop routes: 6h 22m.
Which airport typically offers the quickest layover for flights from St. Louis to Guatemala City?
Average layover duration for 1-stop one-way flights from St. Louis to Guatemala City, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Houston (IAH) offer the fastest connection on this route, with an average layover time of 1h 45m.
Reviews of airlines servicing Guatemala City
Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated May 19, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from St. Louis to Guatemala City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Entertainment
7.8
Boarding
8.1
Food
7.2
Comfort
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Entertainment
7.8
Boarding
8.1
Food
7.2
Comfort
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Entertainment
7.8
Boarding
8.1
Food
7.2
Comfort
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Entertainment
7.8
Boarding
8.1
Food
7.2
Comfort
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Guatemala City?
Book flights to Guatemala City if you plan to visit one of these locationsAntigua
Panajachel
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Other flights to Guatemala City
Explore flights to Guatemala City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 19, 2026.
St. Louis and Guatemala City flights
Browse other St. Louis and Guatemala City flight options. Last updated on May 19, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on May 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from St. Louis to Guatemala City
Discover the top 3 airlines that operate flights from St. Louis to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$457 | Average$583 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$463 | Average$646 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$489 | Average$663 | FlexibilityNo cancel fee | On-timeN/A |