$243+ Cheap flights from St. Louis (STL) to Guatemala City (GUA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GUA
Sep 12 — Sep 191
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from St. Louis to Guatemala City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Guatemala City
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to Guatemala CityExplore the most affordable flight options available from St. Louis to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 13, 2026.
Explore the most affordable flight options available from St. Louis to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 13, 2026.
This Priceline deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/22:59 pm -
1 stop17h 43m
Sun 12/69:57 am -
1 stop21h 12m
Deal found 8/11![Frontier logo]()
$527
This Faresmojo deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am -
1 stop6h 32m
Mon 10/1212:57 pm -
1 stop9h 57m
Deal found 8/11![JetBlue logo]()
$537
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:00 am -
1 stop6h 32m
Wed 10/1412:57 pm -
1 stop7h 26m
Deal found 8/11![Delta logo]()
$600
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am -
1 stop6h 32m
Thu 10/11:02 pm -
1 stop9h 40m
Deal found 8/9![Delta logo]()
$605
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:10 pm -
1 stop18h 55m
Fri 10/96:01 am -
1 stop14h 58m
Deal found 8/10![American Airlines logo]()
$615
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
2 stops14h 23m
Sun 11/86:50 am -
1 stop16h 43m
Deal found 8/11![American Airlines logo]()
$623
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:00 am -
1 stop6h 32m
Tue 10/1312:57 pm -
1 stop9h 57m
Deal found 8/11![Delta logo]()
$630
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am -
1 stop6h 32m
Tue 10/1312:57 pm -
1 stop7h 26m
Deal found 8/11![Delta logo]()
$636
This Air Canada deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:40 pm -
2 stops31h 10m
Fri 10/309:30 am -
2 stops28h 56m
Deal found 8/11![Air Canada logo]()
$640
Best flights from St. Louis to Guatemala CityDiscover carefully curated flight deals from St. Louis to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 13, 2026.
Discover carefully curated flight deals from St. Louis to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 13, 2026.
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop6h 45m
Mon 11/232:10 pm -
1 stop7h 23m
Deal found 8/11![Delta logo]()
$675
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:15 am -
1 stop6h 11m
Wed 12/302:10 am -
1 stop7h 27m
Deal found 8/10![United Airlines logo]()
$689
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/66:00 am -
1 stop6h 45m
Wed 1/133:20 pm -
1 stop8h 19m
Deal found 8/9![Delta logo]()
$675
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:15 am -
1 stop9h 20m
Mon 11/232:10 am -
1 stop7h 52m
Deal found 8/13![United Airlines logo]()
$705
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:30 am -
2 stops11h 09m
Sat 11/72:10 am -
2 stops13h 33m
Deal found 8/9![United Airlines logo]()
$733
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/136:00 am -
1 stop7h 50m
Mon 1/183:20 pm -
1 stop8h 19m
Deal found 8/11![Delta logo]()
$796
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:00 am -
2 stops10h 35m
Wed 11/252:10 am -
1 stop7h 52m
Deal found 8/11![United Airlines logo]()
$820
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:50 pm -
2 stops17h 36m
Mon 11/162:10 am -
2 stops12h 20m
Deal found 8/10![United Airlines logo]()
$845
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:00 am -
2 stops9h 37m
Thu 9/246:15 am -
1 stop13h 01m
Deal found 8/8![United Airlines logo]()
$869
Last-minute flights from St. Louis to Guatemala CityDiscover last-minute flight deals from St. Louis to Guatemala City. Data last updated August 13, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Guatemala City. Data last updated August 13, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/111:15 am -
1 stop6h 22m
Tue 9/86:15 am -
1 stop11h 16m
Deal found 8/11![United Airlines logo]()
$695
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:42 am -
2 stops13h 40m
Tue 9/87:00 am -
2 stops16h 14m
Deal found 8/11![American Airlines logo]()
$699
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:42 am -
1 stop8h 40m
Tue 9/82:23 pm -
2 stops18h 55m
Deal found 8/10![American Airlines logo]()
$716
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/44:23 pm -
1 stop22h 19m
Tue 9/83:47 pm -
2 stops26h 30m
Deal found 8/9![Multiple Airlines logo]()
$733
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:00 am -
2 stops9h 37m
Mon 9/2812:27 pm -
1 stop9h 03m
Deal found 8/10![United Airlines logo]()
$665
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:13 pm -
2 stops18h 33m
Mon 9/2811:46 am -
2 stops11h 41m
Deal found 8/10![American Airlines logo]()
$720
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:00 am -
1 stop14h 29m
Fri 10/26:01 am -
1 stop16h 58m
Deal found 8/11![American Airlines logo]()
$650
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am -
1 stop6h 32m
Thu 10/11:02 pm -
1 stop9h 40m
Deal found 8/9![Delta logo]()
$605
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:00 am -
2 stops9h 20m
Thu 10/12:21 pm -
1 stop8h 38m
Deal found 8/9![American Airlines logo]()
$681
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am -
2 stops11h 37m
Thu 10/110:50 pm -
2 stops12h 23m
Deal found 8/9![United Airlines logo]()
$729
One-way flights from St. Louis to Guatemala CitySearch for one-way flight options from St. Louis to Guatemala City. Find affordable one-way fares based on user searches. Data last updated August 13, 2026.
Search for one-way flight options from St. Louis to Guatemala City. Find affordable one-way fares based on user searches. Data last updated August 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:29 pm -
3 stops47h 17m
Deal found 8/12![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:29 pm -
3 stops47h 17m
Deal found 8/8![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:29 pm -
3 stops47h 17m
Deal found 8/9![Multiple Airlines logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:29 pm -
3 stops47h 17m
Deal found 8/8![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/205:19 pm -
3 stops44h 27m
Deal found 8/8![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:20 am -
2 stops35h 31m
Deal found 8/8![Multiple Airlines logo]()
$288
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:00 am -
2 stops10h 35m
Deal found 8/9![United Airlines logo]()
$305
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:13 pm -
2 stops18h 33m
Deal found 8/12![American Airlines logo]()
$313
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:15 am -
1 stop13h 34m
Deal found 8/12![United Airlines logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:35 am -
3 stops52h 05m
Deal found 8/9![Multiple Airlines logo]()
$334
Find flight deals from St. Louis to Guatemala City
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $527 (Priceline) |
One-way from | $243 (Kiwi.com) |
Popular in | June |
Cheapest in | February |
Average price | $531 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 13, 2026.
Use the filters below to find and compare flights from St. Louis to Guatemala City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Wed 11/18
6:00 am-12:45 pm
1 stop6h 45m
Guatemala City La Aurora
Mon 11/23
2:10 pm-9:33 pm
1 stop7h 23m
$675
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Wed 1/6
6:00 am-12:45 pm
1 stop6h 45m
Guatemala City La Aurora
Wed 1/13
3:20 pm-11:39 pm
1 stop8h 19m
$675
Quickest round-trip
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Tue 12/1
6:15 am-12:26 pm
1 stop6h 11m
Guatemala City La Aurora
Wed 12/30
2:10 am-9:37 am
1 stop7h 27m
$689
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Thu 11/19
6:15 am-3:35 pm
1 stop9h 20m
Guatemala City La Aurora
Mon 11/23
2:10 am-10:02 am
1 stop7h 52m
$705
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Wed 10/28
8:30 am-6:39 pm
2 stops11h 09m
Guatemala City La Aurora
Sat 11/7
2:10 am-3:43 pm
2 stops13h 33m
$733
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Wed 1/13
6:00 am-1:50 pm
1 stop7h 50m
Guatemala City La Aurora
Mon 1/18
3:20 pm-11:39 pm
1 stop8h 19m
$796
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Sat 11/21
5:00 am-3:35 pm
2 stops10h 35m
Guatemala City La Aurora
Wed 11/25
2:10 am-10:02 am
1 stop7h 52m
$820
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Thu 11/12
6:50 pm-12:26 pm
2 stops17h 36m
Guatemala City La Aurora
Mon 11/16
2:10 am-2:30 pm
2 stops12h 20m
$845
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Mon 9/21
8:00 am-4:37 pm
2 stops9h 37m
Guatemala City La Aurora
Thu 9/24
6:15 am-8:16 pm
1 stop13h 01m
$869
Cheapest one-way
St. LouisGuatemala City
STL Lambert-St Louis - GUA Guatemala City La Aurora
STLGUA
Lambert-St Louis
Fri 10/2
2:29 pm-12:46 pm
3 stops47h 17m
$243
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from St. Louis to Guatemala City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Guatemala City in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on St. Louis-Guatemala City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Guatemala City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Guatemala City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Guatemala City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Guatemala City
Have a flexible travel schedule? Discover the best time to fly to Guatemala City from St. Louis with our price prediction graph.
STL-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Guatemala City
Prices
More
What is the cheapest month to book a flight from St. Louis to Guatemala City?
Currently, February is the cheapest month in which you can book a flight from St. Louis to Guatemala City (average of $475). Flying from St. Louis to Guatemala City in June is currently the most expensive (average of $837). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from St. Louis to Guatemala City?
Airfare is typical for this route at the moment.
St. Louis to Guatemala City flights typically cost between $483 and $663 in December.The cheapest round-trip price found within the last 5 days was $527 on Frontier (Dec 2-Dec 6).
What’s the top layover airport for flights from St. Louis to Guatemala City?
Share of 1-stop round-trip flights from St. Louis to Guatemala City chosen by Cheapflights users in the past 12 months, using the same layover each way.
Houston (IAH) – chosen by Cheapflights users on 75% of 1-stop itineraries from St. Louis to Guatemala City on Cheapflights.
What’s the cheapest layover airport for flights from St. Louis to Guatemala City?
Average round-trip fare for 1-stop flights from St. Louis to Guatemala City, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Dallas (DFW) is the most affordable 1-stop option, with an average round-trip price of $542.
What’s the fastest layover option from St. Louis to Guatemala City?
Shortest average travel time for 1-stop one-way flights from St. Louis to Guatemala City, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Houston (IAH) have the shortest average one-way travel time for 1-stop routes: 6h 20m.
Which airport typically offers the quickest layover for flights from St. Louis to Guatemala City?
Average layover duration for 1-stop one-way flights from St. Louis to Guatemala City, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Houston (IAH) offer the fastest connection on this route, with an average layover time of 1h 42m.
Reviews of airlines servicing Guatemala City
Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated August 13, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from St. Louis to Guatemala City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Comfort
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Comfort
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Comfort
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Comfort
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Guatemala City?
Book flights to Guatemala City if you plan to visit one of these locationsAntigua
Panajachel
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Guatemala City flight routes
Other flight options
Other flights from St. Louis
Popular flights
Alternative routes for St. Louis to Guatemala City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Guatemala City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Guatemala City by cabin class
Find flights from St. Louis to Guatemala City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Guatemala City
Explore flights to Guatemala City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 13, 2026.
St. Louis and Guatemala City flights
Browse other St. Louis and Guatemala City flight options. Last updated on August 13, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on August 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from St. Louis to Guatemala City
Discover the top 3 airlines that operate flights from St. Louis to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$457 | Average$629 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$463 | Average$646 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$519 | Average$767 | FlexibilityNo cancel fee | On-timeN/A |