$185+ Cheap flights from St. Louis (STL) to Guatemala City (GUA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/23. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GUA
Mar 30 — Apr 61
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Guatemala City
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Best
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One-way
Cheapest flights from St. Louis to Guatemala CityExplore the most affordable flight options available from St. Louis to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 28, 2026.
Explore the most affordable flight options available from St. Louis to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 28, 2026.
This Priceline deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/94:59 pm
STL
- GUA
1 stop19h 33m
Frontier
Mon 4/1312:37 pm
GUA
- STL
1 stop9h 48m
Frontier
Deal found 2/27![Frontier logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:13 pm
STL
- GUA
2 stops16h 07m
Multiple Airlines
Sat 5/911:16 am
GUA
- STL
1 stop11h 03m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/74:59 pm
STL
- GUA
1 stop15h 58m
Multiple Airlines
Wed 4/155:25 am
GUA
- STL
2 stops16h 54m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$409
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/94:59 pm
STL
- GUA
1 stop19h 33m
Multiple Airlines
Wed 4/155:25 am
GUA
- STL
2 stops16h 54m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$425
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:13 pm
STL
- GUA
2 stops15h 00m
Multiple Airlines
Fri 5/1511:16 am
GUA
- STL
1 stop11h 03m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$428
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/234:59 pm
STL
- GUA
1 stop18h 14m
Multiple Airlines
Sun 4/2612:15 pm
GUA
- STL
2 stops17h 35m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$430
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/118:36 am
STL
- GUA
2 stops27h 48m
Multiple Airlines
Sat 4/1811:16 am
GUA
- STL
1 stop11h 03m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$434
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:00 am
STL
- GUA
1 stop6h 46m
Delta
Tue 4/281:14 pm
GUA
- STL
1 stop9h 22m
Delta
Deal found 2/26![Delta logo]()
$435
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/74:59 pm
STL
- GUA
1 stop15h 58m
Multiple Airlines
Mon 4/1312:59 am
GUA
- STL
2 stops28h 51m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$438
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:45 am
STL
- GUA
2 stops9h 52m
United Airlines
Tue 4/283:45 pm
GUA
- STL
2 stops15h 40m
United Airlines
Deal found 2/26![United Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:27 am
STL
- GUA
2 stops12h 33m
American Airlines
Sat 9/267:15 am
GUA
- STL
2 stops12h 48m
American Airlines
Deal found 2/25![American Airlines logo]()
$442
Best flights from St. Louis to Guatemala CityDiscover carefully curated flight deals from St. Louis to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 28, 2026.
Discover carefully curated flight deals from St. Louis to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 28, 2026.
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:10 am
STL
- GUA
2 stops12h 20m
United Airlines
Tue 5/512:27 pm
GUA
- STL
1 stop9h 03m
United Airlines
Deal found 2/26![United Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:24 am
STL
- GUA
1 stop7h 26m
American Airlines
Tue 4/146:00 am
GUA
- STL
1 stop15h 24m
American Airlines
Deal found 2/27![American Airlines logo]()
$526
This BusinessClass deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:25 am
STL
- GUA
2 stops13h 14m
Multiple Airlines
Mon 3/303:45 pm
GUA
- STL
1 stop16h 40m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$597
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 am
STL
- GUA
1 stop6h 25m
United Airlines
Sun 4/266:15 am
GUA
- STL
1 stop15h 13m
United Airlines
Deal found 2/24![United Airlines logo]()
$470
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:00 am
STL
- GUA
1 stop11h 25m
United Airlines
Mon 3/303:45 pm
GUA
- STL
1 stop16h 40m
United Airlines
Deal found 2/25![United Airlines logo]()
$519
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:14 am
STL
- GUA
1 stop11h 23m
United Airlines
Tue 8/411:55 pm
GUA
- STL
2 stops14h 51m
United Airlines
Deal found 2/24![United Airlines logo]()
$591
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:15 pm
STL
- GUA
2 stops19h 15m
United Airlines
Fri 7/313:45 pm
GUA
- STL
2 stops15h 56m
United Airlines
Deal found 2/25![United Airlines logo]()
$597
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:35 am
STL
- GUA
1 stop27h 49m
United Airlines
Thu 6/113:45 pm
GUA
- STL
2 stops19h 26m
United Airlines
Deal found 2/27![United Airlines logo]()
$603
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/710:09 am
STL
- GUA
1 stop26h 16m
United Airlines
Sat 4/183:45 pm
GUA
- STL
2 stops19h 37m
United Airlines
Deal found 2/26![United Airlines logo]()
$605
Last-minute flights from St. Louis to Guatemala CityDiscover last-minute flight deals from St. Louis to Guatemala City. Data last updated February 28, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Guatemala City. Data last updated February 28, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:00 am
STL
- GUA
1 stop11h 25m
United Airlines
Wed 3/41:28 pm
GUA
- STL
1 stop8h 46m
United Airlines
Deal found 2/26![United Airlines logo]()
$703
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:18 pm
STL
- GUA
1 stop6h 09m
American Airlines
Sat 3/146:00 am
GUA
- STL
1 stop16h 58m
American Airlines
Deal found 2/24![American Airlines logo]()
$643
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:00 am
STL
- GUA
1 stop11h 25m
United Airlines
Mon 3/303:45 pm
GUA
- STL
1 stop16h 40m
United Airlines
Deal found 2/25![United Airlines logo]()
$519
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/94:51 pm
STL
- GUA
1 stop18h 29m
Multiple Airlines
Sun 3/2912:59 am
GUA
- STL
2 stops32h 33m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$573
This BusinessClass deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:25 am
STL
- GUA
2 stops13h 14m
Multiple Airlines
Mon 3/303:45 pm
GUA
- STL
1 stop16h 40m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$597
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:00 am
STL
- GUA
1 stop11h 25m
United Airlines
Mon 3/303:45 pm
GUA
- STL
1 stop16h 40m
United Airlines
Deal found 2/27![United Airlines logo]()
$635
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/274:51 pm
STL
- GUA
1 stop18h 42m
Multiple Airlines
Sun 4/55:25 am
GUA
- STL
2 stops25h 26m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$624
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/284:21 pm
STL
- GUA
1 stop19h 12m
Multiple Airlines
Sat 4/412:23 pm
GUA
- STL
2 stops21h 07m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$606
One-way flights from St. Louis to Guatemala CitySearch for one-way flight options from St. Louis to Guatemala City. Find affordable one-way fares based on user searches. Data last updated February 28, 2026.
Search for one-way flight options from St. Louis to Guatemala City. Find affordable one-way fares based on user searches. Data last updated February 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2312:16 pm
STL
- GUA
2 stops12h 48m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/159:05 pm
STL
- GUA
3 stops51h 59m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$205
This American Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/105:51 am
STL
- GUA
2 stops13h 52m
American Airlines
Deal found 2/25![American Airlines logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/179:50 am
STL
- GUA
3 stops39h 14m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$239
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:30 am
STL
- GUA
1 stop12h 55m
United Airlines
Deal found 2/27![United Airlines logo]()
$348
Find flight deals from St. Louis to Guatemala City
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $338 (Priceline) |
One-way from | $185 (Kiwi.com) |
Popular in | December |
Cheapest in | August |
Average price | $530 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 28, 2026.
Use the filters below to find and compare flights from St. Louis to Guatemala City that are best for you.
Fly from
Fly to
Route
Depart
Return
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Mon 4/27
9:10 am-8:30 pm
2 stops12h 20m
Guatemala City La Aurora
Tue 5/5
12:27 pm-10:30 pm
1 stop9h 03m
$439
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Thu 4/23
6:00 am-11:25 am
1 stop6h 25m
Guatemala City La Aurora
Sun 4/26
6:15 am-10:28 pm
1 stop15h 13m
$470
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Mon 3/9
6:00 am-4:25 pm
1 stop11h 25m
Guatemala City La Aurora
Mon 3/30
3:45 pm-9:25 am
1 stop16h 40m
$519
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Wed 4/8
5:24 am-11:50 am
1 stop7h 26m
Guatemala City La Aurora
Tue 4/14
6:00 am-10:24 pm
1 stop15h 24m
$526
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Wed 7/29
6:14 am-4:37 pm
1 stop11h 23m
Guatemala City La Aurora
Tue 8/4
11:55 pm-3:46 pm
2 stops14h 51m
$591
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Fri 3/20
6:25 am-6:39 pm
2 stops13h 14m
Guatemala City La Aurora
Mon 3/30
3:45 pm-9:25 am
1 stop16h 40m
$597
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Fri 7/24
8:15 pm-2:30 pm
2 stops19h 15m
Guatemala City La Aurora
Fri 7/31
3:45 pm-8:41 am
2 stops15h 56m
$597
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Tue 6/2
8:35 am-11:24 am
1 stop27h 49m
Guatemala City La Aurora
Thu 6/11
3:45 pm-12:11 pm
2 stops19h 26m
$603
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Tue 4/7
10:09 am-11:25 am
1 stop26h 16m
Guatemala City La Aurora
Sat 4/18
3:45 pm-12:22 pm
2 stops19h 37m
$605
St. LouisGuatemala City
STL - GUA
STLGUA
Lambert-St Louis
Sun 5/10
5:51 am-6:43 pm
2 stops13h 52m
$218
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from St. Louis to Guatemala City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Guatemala City in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on St. Louis-Guatemala City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Guatemala City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Guatemala City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Guatemala City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Guatemala City
Have a flexible travel schedule? Discover the best time to fly to Guatemala City from St. Louis with our price prediction graph.
STL-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Guatemala City
What is the cheapest month to book a flight from St. Louis to Guatemala City?
Currently, May is the cheapest month in which you can book a flight from St. Louis to Guatemala City (average of $211). Flying from St. Louis to Guatemala City in December is currently the most expensive (average of $661). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from St. Louis to Guatemala City?
Reviews of airlines servicing Guatemala City
Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated February 28, 2026.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from St. Louis to Guatemala City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Boarding
8.1
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Boarding
8.1
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Boarding
8.1
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Boarding
8.1
Food
7.2
Entertainment
7.8
Overall
7.9
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Guatemala City?
Book flights to Guatemala City if you plan to visit one of these locationsAntigua
Panajachel
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
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Complete your trip
Complete your trip to Guatemala City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Guatemala City by cabin class
Find flights from St. Louis to Guatemala City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Guatemala City
Explore flights to Guatemala City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 28, 2026.
St. Louis and Guatemala City flights
Browse other St. Louis and Guatemala City flight options. Last updated on February 28, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on February 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from St. Louis to Guatemala City
Discover the top 3 airlines that operate flights from St. Louis to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$457 | Average$584 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$457 | Average$568 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$463 | Average$644 | FlexibilityNo cancel fee | On-time71% |