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Guarulhos Intl

$403+ Cheap flights from Knoxville (TYS) to Guarulhos Intl, Brazil (GRU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GRU
Mar 24 — Mar 311
Tue 3/24
Tue 3/31
1 adult, Economy
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Cheap flight deals from Knoxville to Guarulhos Intl

Cheapest flights from Knoxville to Guarulhos Intl
Explore the most affordable flight options available from Knoxville to Guarulhos Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:30 am
TYS
-
GRU
1 stop36h 10m
Multiple Airlines
Sun 5/314:05 am
GRU
-
TYS
2 stops20h 01m
Multiple Airlines
Deal found 2/20$792
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/98:20 am
TYS
-
GRU
1 stop19h 30m
Multiple Airlines
Wed 5/133:15 am
GRU
-
TYS
2 stops18h 35m
Multiple Airlines
Deal found 2/20$799
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:30 am
TYS
-
GRU
1 stop36h 25m
Multiple Airlines
Mon 3/91:00 am
GRU
-
TYS
2 stops20h 42m
Multiple Airlines
Deal found 2/18$842
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/232:06 pm
TYS
-
GRU
2 stops38h 49m
Multiple Airlines
Fri 3/612:45 pm
GRU
-
TYS
1 stop29h 41m
Multiple Airlines
Deal found 2/19$855
This Orbitz deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/243:30 pm
TYS
-
GRU
2 stops51h 50m
LATAM Airlines
Sun 5/319:30 pm
GRU
-
TYS
2 stops27h 19m
LATAM Airlines
Deal found 2/20$1,099
This KAYAK deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/14:38 pm
TYS
-
GRU
2 stops22h 37m
LATAM Airlines
Sat 5/308:15 am
GRU
-
TYS
2 stops16h 34m
LATAM Airlines
Deal found 2/20$1,135
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:48 pm
TYS
-
GRU
1 stop14h 57m
United Airlines
Thu 5/1410:20 pm
GRU
-
TYS
1 stop19h 34m
United Airlines
Deal found 2/20$1,138
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:20 pm
TYS
-
GRU
2 stops18h 00m
American Airlines
Thu 5/1411:15 pm
GRU
-
TYS
2 stops17h 23m
American Airlines
Deal found 2/20$1,142
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:57 pm
TYS
-
GRU
1 stop14h 33m
United Airlines
Sun 5/3110:20 pm
GRU
-
TYS
1 stop15h 59m
United Airlines
Deal found 2/20$1,143
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/19:50 am
TYS
-
GRU
2 stops20h 20m
United Airlines
Sat 5/3010:20 pm
GRU
-
TYS
1 stop19h 41m
United Airlines
Deal found 2/19$1,147
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:39 am
TYS
-
GRU
1 stop23h 01m
Delta
Sun 5/3111:00 pm
GRU
-
TYS
2 stops18h 03m
Delta
Deal found 2/20$1,152

Find flight deals from Knoxville to Guarulhos Intl

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Guarulhos Intl (GRU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$792
(Kiwi.com)

One-way from

$403
(Kiwi.com)
Provider with most accurate pricing for Knoxville McGhee Tyson-Sao Paulo Guarulhos Intl flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Sao Paulo Guarulhos Intl flights.
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From Knoxville McGhee Tyson to Sao Paulo Guarulhos Intl
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One-way flight from Knoxville McGhee Tyson to Sao Paulo Guarulhos Intl
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Guarulhos Intl that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2026.
Use the filters below to find and compare flights from Knoxville to Sao Paulo Guarulhos Intl Airport that are best for you.

Fly from

Knoxville

Fly to

Guarulhos Intl

Route

Depart

Return

Price

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 3/5

6:30 am-8:55 pm

1 stop36h 25m

Sao Paulo Guarulhos Intl

Mon 3/9

1:00 am-8:42 pm

2 stops20h 42m

$842

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sun 5/24

3:30 pm-8:20 pm

2 stops51h 50m

Sao Paulo Guarulhos Intl

Sun 5/31

9:30 pm-11:49 pm

2 stops27h 19m

$1,099

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 5/1

4:38 pm-4:15 pm

2 stops22h 37m

Sao Paulo Guarulhos Intl

Sat 5/30

8:15 am-11:49 pm

2 stops16h 34m

$1,135

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 4/9

5:48 pm-9:45 am

1 stop14h 57m

Sao Paulo Guarulhos Intl

Thu 5/14

10:20 pm-4:54 pm

1 stop19h 34m

$1,138

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sun 5/24

5:57 pm-9:30 am

1 stop14h 33m

Sao Paulo Guarulhos Intl

Sun 5/31

10:20 pm-1:19 pm

1 stop15h 59m

$1,143

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 5/1

10:49 am-9:30 am

1 stop21h 41m

Sao Paulo Guarulhos Intl

Sat 5/30

10:20 pm-5:01 pm

1 stop19h 41m

$1,143

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sun 5/24

5:39 am-5:40 am

1 stop23h 01m

Sao Paulo Guarulhos Intl

Sun 5/31

11:00 pm-4:03 pm

2 stops18h 03m

$1,152

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 4/23

4:38 pm-7:15 pm

2 stops25h 37m

$663

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 4/23

4:09 pm-9:00 am

1 stop15h 51m

$668

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 3/27

7:00 am-7:15 am

1 stop23h 15m

$704

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/18

Showing 1-10 of 11 results
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Compare providers for flights from Knoxville to Guarulhos Intl

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Guarulhos Intl in February.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Sao Paulo Guarulhos Intl Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Sao Paulo Guarulhos Intl Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Sao Paulo Guarulhos Intl Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Sao Paulo Guarulhos Intl Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Sao Paulo Guarulhos Intl Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Guarulhos Intl

Have a flexible travel schedule? Discover the best time to fly to Guarulhos Intl from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Guarulhos Intl. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Sao Paulo Guarulhos Intl?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Sao Paulo Guarulhos Intl. On average, McGhee Tyson has 0 outbound flights to Sao Paulo Guarulhos Intl per day from 0 airlines. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • How long is the flight from Knoxville to Sao Paulo Guarulhos Intl Airport?

    Airlines like LATAM Airlines fly from Knoxville to Sao Paulo Guarulhos Intl Airport in about 51h 50m. The time it takes to get you to your destination can typically vary by up to . The distance from Knoxville to Sao Paulo Guarulhos Intl Airport is about 4768 mi.

  • Can I find deals for flights from Knoxville to Guarulhos Intl that include hotel bookings?

    Yes. In addition to deals on Knoxville to Guarulhos Intl flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Guarulhos Intl?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Guarulhos Intl.

  • Can I find deals for business class flights from Knoxville to Guarulhos Intl?

    Yes. Cheapflights offers flight deals from Knoxville to Guarulhos Intl by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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