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Guanajuato

$523+ Cheap flights from Des Moines (DSM) to Guanajuato, Mexico, Mexico

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — BJX
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
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Cheap flight deals from Des Moines to Guanajuato

Keep the following information in mind while searching for Des Moines to Guanajuato flight deals. Data was last updated January 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$523
(American Airlines)

Popular in

December

Cheapest in

April

Average price

$931
Provider with most accurate pricing for Des Moines-León Del Bajio flight deals.
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Provider most trusted by Cheapflights users for Des Moines-León Del Bajio flights.
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From Des Moines to Guanajuato
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Highest demand for flights based on searches. 21% potential increase in price ($186 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($25 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Des Moines to Guanajuato

Cheapest flights from Des Moines to Guanajuato
Explore the most affordable flight options available from Des Moines to Guanajuato. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/287:27 pmDSM - BJX
1 stop26h 31mAmerican Airlines
Sat 4/48:00 amBJX - DSM
1 stop14h 46mAmerican Airlines
Deal found 1/6$523
This United Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/55:30 amDSM - BJX
2 stops13h 14mUnited Airlines
Tue 2/245:55 amBJX - DSM
1 stop8h 22mUnited Airlines
Deal found 1/7$539
This United Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/19:00 amDSM - BJX
2 stops11h 31mUnited Airlines
Wed 4/155:00 amBJX - DSM
2 stops10h 15mUnited Airlines
Deal found 1/6$543
This Delta deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:04 amDSM - BJX
1 stop8h 28mDelta
Sun 9/208:08 amBJX - DSM
1 stop13h 18mDelta
Deal found 1/8$559
This Delta deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/285:35 amDSM - BJX
2 stops14h 35mDelta
Sat 4/49:35 amBJX - DSM
1 stop12h 03mDelta
Deal found 1/7$579
This Aeromexico deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:15 pmDSM - BJX
2 stops17h 58mAeromexico
Sun 9/208:10 pmBJX - DSM
2 stops25h 16mAeromexico
Deal found 1/8$589
This Aeromexico deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2811:33 amDSM - BJX
2 stops12h 47mAeromexico
Sat 4/46:00 amBJX - DSM
2 stops15h 38mAeromexico
Deal found 1/6$619
This Aeromexico deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/255:35 amDSM - BJX
1 stop10h 57mAeromexico
Wed 1/285:50 amBJX - DSM
2 stops10h 38mAeromexico
Deal found 1/7$679
This United Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/286:49 pmDSM - BJX
2 stops19h 54mUnited Airlines
Sat 4/45:00 amBJX - DSM
2 stops10h 15mUnited Airlines
Deal found 1/7$680

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Guanajuato that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Des Moines to Guanajuato that are best for you.

Fly from

Des Moines

Fly to

Guanajuato

Route

Depart

Return

Price

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

Sat 3/28

7:27 pm-8:58 pm

1 stop26h 31m

León Del Bajio

Sat 4/4

8:00 am-11:46 pm

1 stop14h 46m

$523

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

Wed 4/1

8:20 am-1:43 pm

1 stop6h 23m

León Del Bajio

Wed 4/15

2:50 pm-10:43 pm

1 stop6h 53m

$539

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

Thu 2/5

5:30 am-6:44 pm

2 stops13h 14m

León Del Bajio

Tue 2/24

5:55 am-2:17 pm

1 stop8h 22m

$539

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

Sat 3/28

5:35 am-7:10 pm

2 stops14h 35m

León Del Bajio

Sat 4/4

9:35 am-10:38 pm

1 stop12h 03m

$579

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

Sun 1/25

5:35 am-6:27 pm

2 stops12h 52m

León Del Bajio

Wed 1/28

5:50 am-4:28 pm

2 stops10h 38m

$679

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/6

Best time to book a flight from Des Moines to Guanajuato

Have a flexible travel schedule? Discover the best time to fly to Guanajuato from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Guanajuato

What is the cheapest month to book a flight from Des Moines to Guanajuato?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Guanajuato (average of $441). Flying from Des Moines to Guanajuato in January is currently the most expensive (average of $786). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Guanajuato?

Reviews of airlines servicing Guanajuato

Get insights into the airlines that provide service to Guanajuato. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guanajuato. Reviews last updated January 8, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Des Moines to Guanajuato. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,139 reviews

Entertainment

7.1

Boarding

7.7

Food

6.6

Overall

7.4

Comfort

7.3

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

IAD - TYS

It was a short flight on a small express plane, so no time for amenities. Quickly on, quickly off. No complaints.
United Airlines
7.4
Good
9,139 reviews
United Airlines
7.4
Good
9,139 reviews

Entertainment

7.1

Boarding

7.7

Food

6.6

Overall

7.4

Comfort

7.3

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

IAD - TYS

It was a short flight on a small express plane, so no time for amenities. Quickly on, quickly off. No complaints.
American Airlines
7.2
Good
11,095 reviews
United Airlines
7.4
Good
9,139 reviews

Entertainment

7.1

Boarding

7.7

Food

6.6

Overall

7.4

Comfort

7.3

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

IAD - TYS

It was a short flight on a small express plane, so no time for amenities. Quickly on, quickly off. No complaints.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guanajuato. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Guanajuato?

    If you book a flight to Guanajuato from Des Moines, you will be flying from Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines. There are 0 flights from Des Moines to Guanajuato per day from 2 different airlines.

  • How long is the flight from Des Moines to Guanajuato?

    A quick flight from Des Moines to Guanajuato can take about 6h 23m. American Airlines provides one of the quickest options available for as low as $539. Des Moines and Guanajuato are separated by a distance of 1490 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Des Moines to Guanajuato that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guanajuato flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guanajuato?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guanajuato.

  • Can I find deals for business class flights from Des Moines to Guanajuato?

    Yes. Cheapflights offers flight deals from Des Moines to Guanajuato by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Guanajuato?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Guanajuato (average of $441). Flying from Des Moines to Guanajuato in January is currently the most expensive (average of $786). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Guanajuato

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Des Moines to Guanajuato

Discover the top 2 airlines that operate flights from Des Moines to Guanajuato. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$486Average$781FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$517Average$681FlexibilityNo cancel feeOn-time69%

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