HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Guanajuato

$394+ Cheap flights from Des Moines (DSM) to Guanajuato, Mexico, Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — BJX
nov. 22 — nov. 291
sáb. 11/22
sáb. 11/29
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Guanajuato with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Des Moines to Guanajuato

Cheapest flights from Des Moines to Guanajuato
Explore the most affordable flight options available from Des Moines to Guanajuato. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 23, 2025.

This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/45:45 amDSM - BJX
2 stops8h 58mUnited Airlines
mar. 11/1112:50 pmBJX - DSM
1 stop9h 30mUnited Airlines
Deal found 10/23$607
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/55:00 amDSM - BJX
1 stop18h 22mAmerican Airlines
vie. 12/124:08 pmBJX - DSM
1 stop24h 47mAmerican Airlines
Deal found 10/20$617
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/76:00 pmDSM - BJX
1 stop16h 53mAmerican Airlines
vie. 11/1412:04 pmBJX - DSM
1 stop10h 55mAmerican Airlines
Deal found 10/21$627
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/66:50 pmDSM - BJX
2 stops17h 04mUnited Airlines
sáb. 12/135:55 amBJX - DSM
1 stop8h 17mUnited Airlines
Deal found 10/23$651
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/56:50 pmDSM - BJX
2 stops23h 54mUnited Airlines
vie. 12/1212:50 pmBJX - DSM
1 stop9h 39mUnited Airlines
Deal found 10/20$682
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/66:00 pmDSM - BJX
1 stop21h 12mAmerican Airlines
sáb. 12/136:07 amBJX - DSM
1 stop8h 44mAmerican Airlines
Deal found 10/23$688
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/128:15 amDSM - BJX
1 stop10h 29mUnited Airlines
mié. 12/1712:50 pmBJX - DSM
1 stop9h 39mUnited Airlines
Deal found 10/23$693

Cheap flight deals from Des Moines to Guanajuato

Keep the following information in mind while searching for Des Moines to Guanajuato flight deals. Data was last updated octubre 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$529
(Aeromexico)

One-way from

$394
(United Airlines)

Popular in

December

Cheapest in

January

Average price

$716
Provider with most accurate pricing for Des Moines-León Del Bajio flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-León Del Bajio flights.
Search Deals
From Des Moines to Guanajuato
Search Deals
One-way flight from Des Moines to Guanajuato
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($63 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Guanajuato that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 23, 2025.
Use the filters below to find and compare flights from Des Moines to Guanajuato that are best for you.

Fly from

Des Moines

Fly to

Guanajuato

Route

Depart

Return

Price

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

mié. 1/14

11:04 am-9:11 am

2 stops22h 07m

León Del Bajio

mié. 2/4

9:56 am-10:28 pm

1 stop12h 32m

$529

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

lun. 1/19

7:00 am-9:01 pm

2 stops14h 01m

León Del Bajio

jue. 2/5

5:55 am-4:30 pm

2 stops10h 35m

$529

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

mar. 1/13

5:45 am-9:05 am

2 stops27h 20m

León Del Bajio

mar. 2/3

7:44 am-10:28 pm

2 stops14h 44m

$529

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

mar. 1/13

5:45 am-4:32 pm

1 stop10h 47m

León Del Bajio

jue. 2/5

5:55 am-4:30 pm

2 stops10h 35m

$529

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

jue. 1/15

5:45 am-4:32 pm

1 stop10h 47m

León Del Bajio

sáb. 2/7

7:54 am-10:28 pm

2 stops14h 34m

$549

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

lun. 1/19

7:00 am-4:13 pm

2 stops9h 13m

León Del Bajio

sáb. 2/7

5:55 am-10:28 pm

2 stops16h 33m

$549

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

vie. 1/16

5:45 am-4:32 pm

1 stop10h 47m

León Del Bajio

vie. 2/6

7:54 am-10:28 pm

2 stops14h 34m

$569

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

lun. 1/19

5:45 am-4:32 pm

1 stop10h 47m

León Del Bajio

mar. 2/3

7:44 am-10:28 pm

2 stops14h 44m

$569

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

jue. 1/15

5:45 am-4:32 pm

1 stop10h 47m

León Del Bajio

mié. 2/4

5:55 am-4:30 pm

2 stops10h 35m

$569

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

vie. 1/16

5:45 am-4:32 pm

1 stop10h 47m

León Del Bajio

sáb. 2/7

5:55 am-10:28 pm

2 stops16h 33m

$569

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/21

Showing 1-10 of 15 results
1
2

Best time to book a flight from Des Moines to Guanajuato

Have a flexible travel schedule? Discover the best time to fly to Guanajuato from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Guanajuato

What is the cheapest month to book a flight from Des Moines to Guanajuato?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Guanajuato (average of $454). Flying from Des Moines to Guanajuato in March is currently the most expensive (average of $622). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to GJ9?

Find hourly flight availability from Des Moines to Guanajuato. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 23, 2025.

It’s typically best to fly out from Des Moines to Guanajuato in the evening. Doing so could potentially save you 35% on the flight price compared to flying in the morning, which is usually more expensive.

How much does it cost to fly round-trip from Des Moines to Guanajuato?

Reviews of airlines servicing Guanajuato

Get insights into the airlines that provide service to Guanajuato. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guanajuato. Reviews last updated octubre 23, 2025.
Read reviews from past customers who have flown United Airlines and American Airlines from Des Moines to Guanajuato. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,995 reviews

Comfort

7.3

Entertainment

7.1

Crew

8.1

Boarding

7.7

Food

6.6

Overall

7.4

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.
United Airlines
7.4
Good
8,995 reviews
United Airlines
7.4
Good
8,995 reviews

Comfort

7.3

Entertainment

7.1

Crew

8.1

Boarding

7.7

Food

6.6

Overall

7.4

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.
American Airlines
7.2
Good
11,032 reviews
United Airlines
7.4
Good
8,995 reviews

Comfort

7.3

Entertainment

7.1

Crew

8.1

Boarding

7.7

Food

6.6

Overall

7.4

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guanajuato. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Guanajuato?

    If you book a flight to Guanajuato from Des Moines, you will be flying from Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines. There are 0 flights from Des Moines to Guanajuato per day from 2 different airlines.

  • How long is the flight from Des Moines to Guanajuato?

    A quick flight from Des Moines to Guanajuato can take about 22h 07m. Aeromexico provides one of the quickest options available for as low as $529. Des Moines and Guanajuato are separated by a distance of 1490 mi.

  • Can I find deals for flights from Des Moines to Guanajuato that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guanajuato flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guanajuato?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guanajuato.

  • Can I find deals for business class flights from Des Moines to Guanajuato?

    Yes. Cheapflights offers flight deals from Des Moines to Guanajuato by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Guanajuato?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to Guanajuato (average of $454). Flying from Des Moines to Guanajuato in March is currently the most expensive (average of $622). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Guanajuato

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to León flights
Des Moines to León flights
Omaha to Santiago de Querétaro flights
Cedar Rapids to León flights
Moline to León flights

Top 2 airlines flying from Des Moines to Guanajuato

Discover the top 2 airlines that operate flights from Des Moines to Guanajuato. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$326Average$655FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$517Average$723FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.