$148+ Cheap flights from Panama City, FL to Greenville (ECP - GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — GSP
Sep 14 — Sep 211
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Panama City to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Greenville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama City to GreenvilleExplore the most affordable flight options available from Panama City to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 15, 2026.
Explore the most affordable flight options available from Panama City to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 15, 2026.
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am -
1 stop4h 08m
Tue 9/158:05 am -
1 stop5h 34m
Deal found 8/11![Delta logo]()
$233
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am -
1 stop4h 08m
Fri 9/115:45 am -
1 stop3h 31m
Deal found 8/11![Delta logo]()
$256
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:30 pm -
1 stop4h 25m
Fri 9/185:45 am -
1 stop3h 31m
Deal found 8/11![Delta logo]()
$264
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am -
1 stop4h 08m
Thu 9/106:25 pm -
1 stop5h 40m
Deal found 8/11![Delta logo]()
$295
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:46 pm -
1 stop5h 51m
Tue 9/155:45 am -
1 stop5h 49m
Deal found 8/11![Delta logo]()
$296
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:00 pm -
1 stop5h 59m
Sat 11/146:30 am -
1 stop8h 02m
Deal found 8/11![United Airlines logo]()
$303
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:46 pm -
1 stop5h 51m
Fri 9/115:45 am -
1 stop3h 31m
Deal found 8/11![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am -
1 stop5h 41m
Thu 9/35:46 am -
1 stop3h 45m
Deal found 8/11![Delta logo]()
$335
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:46 pm -
1 stop5h 51m
Thu 9/105:45 am -
1 stop3h 31m
Deal found 8/11![Delta logo]()
$358
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:45 am -
1 stop3h 40m
Fri 9/187:00 am -
2 stops6h 50m
Deal found 8/11![Southwest logo]()
$387
Best flights from Panama City to GreenvilleDiscover carefully curated flight deals from Panama City to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 15, 2026.
Discover carefully curated flight deals from Panama City to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 15, 2026.
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:30 pm -
1 stop4h 25m
Fri 9/185:45 am -
1 stop3h 31m
Deal found 8/11![Delta logo]()
$264
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:00 pm -
1 stop5h 59m
Sat 11/146:30 am -
1 stop8h 02m
Deal found 8/10![United Airlines logo]()
$303
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:30 am -
2 stops9h 25m
Thu 9/37:00 am -
2 stops6h 50m
Deal found 8/11![Southwest logo]()
$536
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:46 pm -
1 stop5h 51m
Mon 9/146:57 pm -
2 stops14h 19m
Deal found 8/11![Delta logo]()
$490
Last-minute flights from Panama City to GreenvilleDiscover last-minute flight deals from Panama City to Greenville. Data last updated August 15, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Greenville. Data last updated August 15, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am -
1 stop5h 41m
Thu 9/35:46 am -
1 stop3h 45m
Deal found 8/11![Delta logo]()
$335
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:35 am -
1 stop12h 02m
Wed 9/165:45 am -
1 stop3h 31m
Deal found 8/11![Delta logo]()
$395
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:46 pm -
1 stop5h 51m
Wed 9/165:45 am -
1 stop3h 31m
Deal found 8/11![Delta logo]()
$296
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:46 pm -
1 stop5h 51m
Fri 9/115:45 am -
1 stop3h 31m
Deal found 8/11![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:46 pm -
1 stop5h 51m
Thu 9/105:45 am -
1 stop3h 31m
Deal found 8/11![Delta logo]()
$358
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am -
1 stop4h 08m
Tue 9/158:05 am -
1 stop5h 34m
Deal found 8/11![Delta logo]()
$233
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am -
1 stop4h 08m
Fri 9/115:45 am -
1 stop3h 31m
Deal found 8/11![Delta logo]()
$256
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am -
1 stop4h 08m
Thu 9/106:25 pm -
1 stop5h 40m
Deal found 8/11![Delta logo]()
$295
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:30 pm -
1 stop4h 25m
Fri 9/185:45 am -
1 stop3h 31m
Deal found 8/11![Delta logo]()
$264
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:45 am -
1 stop3h 40m
Fri 9/187:00 am -
2 stops6h 50m
Deal found 8/11![Southwest logo]()
$387
One-way flights from Panama City to GreenvilleSearch for one-way flight options from Panama City to Greenville. Find affordable one-way fares based on user searches. Data last updated August 15, 2026.
Search for one-way flight options from Panama City to Greenville. Find affordable one-way fares based on user searches. Data last updated August 15, 2026.
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:19 pm -
1 stop3h 41m
Deal found 8/10![Delta logo]()
$148
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am -
1 stop3h 02m
Deal found 8/12![Delta logo]()
$180
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/281:30 pm -
1 stop3h 50m
Deal found 8/12![Southwest logo]()
$211
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2911:42 am -
2 stops10h 16m
Deal found 8/12![American Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:42 am -
1 stop5h 54m
Deal found 8/14![American Airlines logo]()
$324
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:51 pm -
1 stop3h 08m
Deal found 8/14![Delta logo]()
$341
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:53 pm -
1 stop5h 39m
Deal found 8/14![Delta logo]()
$353
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:42 am -
2 stops10h 16m
Deal found 8/14![American Airlines logo]()
$358
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:27 pm -
1 stop6h 31m
Deal found 8/14![United Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:00 am -
2 stops9h 15m
Deal found 8/14![Southwest logo]()
$394
Find flight deals from Panama City to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $233 (Delta) |
One-way from | $148 (Delta) |
Popular in | April |
Cheapest in | September |
Average price | $390 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 15, 2026.
Use the filters below to find and compare flights from Panama City to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CityGreenville
ECP Panama City NW Florida Beaches - GSP Greenville
ECPGSP
Panama City NW Florida Beaches
Tue 9/15
5:30 pm-10:55 pm
1 stop4h 25m
Greenville
Fri 9/18
5:45 am-8:16 am
1 stop3h 31m
$264
Panama CityGreenville
ECP Panama City NW Florida Beaches - GSP Greenville
ECPGSP
Panama City NW Florida Beaches
Wed 11/11
3:00 pm-9:59 pm
1 stop5h 59m
Greenville
Sat 11/14
6:30 am-1:32 pm
1 stop8h 02m
$303
Panama CityGreenville
ECP Panama City NW Florida Beaches - GSP Greenville
ECPGSP
Panama City NW Florida Beaches
Wed 9/9
1:46 pm-8:37 pm
1 stop5h 51m
Greenville
Mon 9/14
6:57 pm-8:16 am
2 stops14h 19m
$490
Panama CityGreenville
ECP Panama City NW Florida Beaches - GSP Greenville
ECPGSP
Panama City NW Florida Beaches
Tue 9/1
10:30 am-8:55 pm
2 stops9h 25m
Greenville
Thu 9/3
7:00 am-12:50 pm
2 stops6h 50m
$536
Cheapest one-way
Panama CityGreenville
ECP Panama City NW Florida Beaches - GSP Greenville
ECPGSP
Panama City NW Florida Beaches
Fri 10/2
6:19 pm-11:00 pm
1 stop3h 41m
$148
Panama CityGreenville
ECP Panama City NW Florida Beaches - GSP Greenville
ECPGSP
Panama City NW Florida Beaches
Sat 8/29
6:00 am-10:02 am
1 stop3h 02m
$180
Panama CityGreenville
ECP Panama City NW Florida Beaches - GSP Greenville
ECPGSP
Panama City NW Florida Beaches
Fri 8/28
1:30 pm-6:20 pm
1 stop3h 50m
$211
Quickest one-way
Panama CityGreenville
ECP Panama City NW Florida Beaches - GSP Greenville
ECPGSP
Panama City NW Florida Beaches
Wed 8/19
9:27 am-1:14 pm
1 stop2h 47m
$353
Panama CityGreenville
ECP Panama City NW Florida Beaches - GSP Greenville
ECPGSP
Panama City NW Florida Beaches
Tue 8/18
1:53 pm-8:32 pm
1 stop5h 39m
$353
Panama CityGreenville
ECP Panama City NW Florida Beaches - GSP Greenville
ECPGSP
Panama City NW Florida Beaches
Thu 8/20
6:00 am-10:40 am
1 stop3h 40m
$389
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Panama City to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Greenville in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Panama City with our price prediction graph.
ECP-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated August 15, 2026.
Peruse reviews from past customers who have flown with Delta from Panama City to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Overall
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Comfort
7.8
Overall
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Related info for your journey
Find useful and relevant information for your journey from Panama City to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Greenville flight routes
Other flight options
Other flights from Panama City
Popular flights
Alternative routes for Panama City to Greenville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Greenville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Greenville by cabin class
Find flights from Panama City to Greenville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 15, 2026.
Panama City and Greenville flights
Browse other Panama City and Greenville flight options. Last updated on August 15, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on August 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Panama City to Greenville
Discover the top airline that operate flights from Panama City to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$185 | Average$333 | FlexibilityNo cancel fee | On-timeN/A |