$301+ Cheap flights from Medford to Greenville (MFR - GSP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — GSP
Nov 24 — Dec 11
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Medford to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Medford to Greenville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Medford to GreenvilleExplore the most affordable flight options available from Medford to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Medford to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:15 am -
2 stops12h 06m
Fri 11/205:40 am -
2 stops10h 11m
Deal found 10/22![Delta logo]()
$469
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:01 am -
1 stop7h 01m
Tue 11/174:29 pm -
1 stop7h 49m
Deal found 10/22![United Airlines logo]()
$492
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:11 am -
2 stops13h 40m
Tue 11/1710:56 am -
2 stops15h 31m
Deal found 10/22![Delta logo]()
$499
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:04 am -
2 stops13h 54m
Sat 11/147:51 am -
2 stops11h 54m
Deal found 10/23![American Airlines logo]()
$502
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:11 am -
2 stops13h 40m
Tue 11/105:40 am -
2 stops10h 11m
Deal found 10/22![Delta logo]()
$539
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:30 pm -
2 stops18h 41m
Sat 11/1412:59 pm -
2 stops13h 28m
Deal found 10/22![Delta logo]()
$552
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:01 am -
1 stop7h 01m
Thu 11/194:29 pm -
1 stop7h 49m
Deal found 10/22![United Airlines logo]()
$569
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:45 pm -
2 stops11h 17m
Tue 11/174:29 pm -
1 stop7h 49m
Deal found 10/22![United Airlines logo]()
$574
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:45 pm -
2 stops11h 17m
Wed 11/1810:42 am -
2 stops13h 36m
Deal found 10/22![United Airlines logo]()
$579
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:01 am -
1 stop7h 02m
Sat 11/144:29 pm -
1 stop7h 49m
Deal found 10/22![United Airlines logo]()
$587
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:15 am -
2 stops12h 06m
Mon 11/163:47 pm -
2 stops10h 40m
Deal found 10/22![Delta logo]()
$588
Best flights from Medford to GreenvilleDiscover carefully curated flight deals from Medford to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Medford to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:11 am -
2 stops13h 40m
Fri 11/135:40 am -
2 stops10h 11m
Deal found 10/22![Delta logo]()
$499
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:45 pm -
2 stops11h 17m
Tue 11/1710:26 am -
2 stops10h 43m
Deal found 10/22![United Airlines logo]()
$502
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/305:00 am -
2 stops13h 03m
Wed 2/36:30 am -
2 stops14h 43m
Deal found 10/24![United Airlines logo]()
$539
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:01 am -
1 stop7h 01m
Wed 11/1810:42 am -
2 stops13h 36m
Deal found 10/22![United Airlines logo]()
$574
This deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:01 am -
1 stop7h 02m
Tue 11/174:29 pm -
1 stop7h 49m
Deal found 10/23![United Airlines logo]()
$587
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:45 pm -
2 stops11h 06m
Tue 11/106:20 am -
2 stops14h 49m
Deal found 10/22![United Airlines logo]()
$619
This deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:01 am -
1 stop7h 02m
Tue 11/174:29 pm -
1 stop7h 49m
Deal found 10/23![United Airlines logo]()
$622
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:45 pm -
2 stops11h 17m
Wed 11/184:29 pm -
1 stop7h 49m
Deal found 10/22![United Airlines logo]()
$627
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:01 am -
1 stop7h 02m
Mon 11/164:29 pm -
1 stop7h 49m
Deal found 10/22![United Airlines logo]()
$680
Last-minute flights from Medford to GreenvilleDiscover last-minute flight deals from Medford to Greenville. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Medford to Greenville. Data last updated October 25, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:04 am -
2 stops13h 54m
Sat 11/147:51 am -
2 stops11h 54m
Deal found 10/23![American Airlines logo]()
$502
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:01 am -
1 stop7h 02m
Sat 11/144:29 pm -
1 stop7h 49m
Deal found 10/22![United Airlines logo]()
$587
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:01 am -
1 stop7h 01m
Tue 11/174:29 pm -
1 stop7h 49m
Deal found 10/22![United Airlines logo]()
$492
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:45 pm -
2 stops11h 17m
Tue 11/174:29 pm -
1 stop7h 49m
Deal found 10/22![United Airlines logo]()
$574
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:45 pm -
2 stops11h 17m
Wed 11/1810:42 am -
2 stops13h 36m
Deal found 10/22![United Airlines logo]()
$579
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:11 am -
2 stops13h 40m
Tue 11/1710:56 am -
2 stops15h 31m
Deal found 10/22![Delta logo]()
$499
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:11 am -
2 stops13h 40m
Tue 11/105:40 am -
2 stops10h 11m
Deal found 10/22![Delta logo]()
$539
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:15 am -
2 stops12h 06m
Fri 11/205:40 am -
2 stops10h 11m
Deal found 10/22![Delta logo]()
$469
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:01 am -
1 stop7h 01m
Tue 11/174:29 pm -
1 stop7h 49m
Deal found 10/22![United Airlines logo]()
$569
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:15 am -
2 stops12h 06m
Mon 11/163:47 pm -
2 stops10h 40m
Deal found 10/22![Delta logo]()
$588
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:30 pm -
2 stops18h 41m
Sat 11/1412:59 pm -
2 stops13h 28m
Deal found 10/22![Delta logo]()
$552
One-way flights from Medford to GreenvilleSearch for one-way flight options from Medford to Greenville. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Medford to Greenville. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/317:59 pm -
3 stops38h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$301
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/315:00 am -
1 stop7h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/15:00 am -
2 stops12h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$522
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/15:40 am -
3 stops47h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$793
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/15:00 am -
1 stop7h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$895
Find flight deals from Medford to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $469 (Delta) |
One-way from | $301 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Medford to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Medford to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Thu 12/31
5:00 am-3:16 pm
1 stop7h 16m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$454
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Sat 11/7
6:11 am-10:51 pm
2 stops13h 40m
Greenville
Fri 11/13
5:40 am-12:51 pm
2 stops10h 11m
$499
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Thu 11/5
7:45 pm-10:02 am
2 stops11h 17m
Greenville
Tue 11/17
10:26 am-6:09 pm
2 stops10h 43m
$502
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Sat 1/30
5:00 am-9:03 pm
2 stops13h 03m
Greenville
Wed 2/3
6:30 am-6:13 pm
2 stops14h 43m
$539
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Sun 11/8
5:01 am-3:02 pm
1 stop7h 01m
Greenville
Wed 11/18
10:42 am-9:18 pm
2 stops13h 36m
$574
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Wed 11/4
5:01 am-3:03 pm
1 stop7h 02m
Greenville
Tue 11/17
4:29 pm-9:18 pm
1 stop7h 49m
$587
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Fri 11/6
7:45 pm-9:51 am
2 stops11h 06m
Greenville
Tue 11/10
6:20 am-6:09 pm
2 stops14h 49m
$619
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Fri 11/6
5:01 am-3:03 pm
1 stop7h 02m
Greenville
Tue 11/17
4:29 pm-9:18 pm
1 stop7h 49m
$622
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Thu 11/5
7:45 pm-10:02 am
2 stops11h 17m
Greenville
Wed 11/18
4:29 pm-9:18 pm
1 stop7h 49m
$627
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Wed 11/4
5:01 am-3:03 pm
1 stop7h 02m
Greenville
Mon 11/16
4:29 pm-9:18 pm
1 stop7h 49m
$680
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Medford to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to Greenville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Medford-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Medford-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Medford to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Medford with our price prediction graph.
MFR-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Medford to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Greenville flight routes
Other flight options
Other flights from Medford
Popular flights