$310+ Cheap flights from Medford to Greenville (MFR - GSP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — GSP
Dec 4 — Dec 111
Round-trip
1 adult, Economy
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Find cheap flights from Medford to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Medford to Greenville
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Cheapest flights from Medford to GreenvilleExplore the most affordable flight options available from Medford to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
Explore the most affordable flight options available from Medford to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:00 am -
1 stop7h 12m
Mon 12/144:18 pm -
1 stop8h 08m
Deal found 11/3![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:15 am -
2 stops11h 42m
Mon 12/142:07 pm -
2 stops12h 29m
Deal found 11/3![Delta logo]()
$409
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:00 am -
1 stop7h 12m
Fri 12/114:18 pm -
1 stop8h 08m
Deal found 11/3![United Airlines logo]()
$411
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:15 am -
2 stops10h 15m
Mon 12/1410:57 am -
2 stops15h 39m
Deal found 11/3![Delta logo]()
$418
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:26 pm -
2 stops14h 41m
Sun 11/227:00 am -
2 stops12h 46m
Deal found 11/3![Delta logo]()
$489
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:00 am -
1 stop7h 12m
Sun 12/136:30 am -
2 stops9h 51m
Deal found 10/31![United Airlines logo]()
$491
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:00 am -
1 stop7h 12m
Mon 12/1412:15 pm -
2 stops12h 11m
Deal found 11/3![United Airlines logo]()
$496
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:01 am -
1 stop7h 02m
Sun 11/224:29 pm -
1 stop7h 49m
Deal found 11/3![United Airlines logo]()
$503
Best flights from Medford to GreenvilleDiscover carefully curated flight deals from Medford to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
Discover carefully curated flight deals from Medford to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:00 am -
1 stop7h 12m
Sun 12/134:18 pm -
1 stop8h 08m
Deal found 10/31![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:10 am -
2 stops14h 37m
Mon 12/142:07 pm -
2 stops12h 29m
Deal found 11/3![Delta logo]()
$409
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:04 am -
2 stops13h 48m
Mon 12/147:55 am -
2 stops11h 51m
Deal found 11/3![American Airlines logo]()
$633
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:15 am -
2 stops10h 15m
Mon 12/1410:57 am -
2 stops15h 39m
Deal found 11/3![Delta logo]()
$418
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:15 am -
2 stops11h 42m
Mon 12/142:07 pm -
2 stops12h 29m
Deal found 11/3![Delta logo]()
$419
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:00 am -
1 stop7h 12m
Tue 12/86:30 am -
2 stops9h 51m
Deal found 11/3![United Airlines logo]()
$534
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/305:00 am -
2 stops13h 59m
Wed 2/36:30 am -
2 stops14h 43m
Deal found 10/31![United Airlines logo]()
$539
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/96:00 am -
2 stops10h 07m
Tue 2/2310:28 am -
2 stops14h 02m
Deal found 10/31![United Airlines logo]()
$539
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/85:05 am -
2 stops10h 51m
Fri 1/225:38 am -
2 stops9h 16m
Deal found 10/31![Delta logo]()
$629
Last-minute flights from Medford to GreenvilleDiscover last-minute flight deals from Medford to Greenville. Data last updated November 4, 2026 and is based on user searches.
Discover last-minute flight deals from Medford to Greenville. Data last updated November 4, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:26 pm -
2 stops14h 41m
Sun 11/227:00 am -
2 stops12h 46m
Deal found 11/3![Delta logo]()
$489
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:01 am -
1 stop7h 02m
Sun 11/224:29 pm -
1 stop7h 49m
Deal found 11/3![United Airlines logo]()
$503
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:00 am -
1 stop7h 12m
Fri 12/114:18 pm -
1 stop8h 08m
Deal found 11/3![United Airlines logo]()
$411
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:00 am -
1 stop7h 12m
Mon 12/144:18 pm -
1 stop8h 08m
Deal found 11/3![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:15 am -
2 stops10h 15m
Mon 12/1410:57 am -
2 stops15h 39m
Deal found 11/3![Delta logo]()
$418
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:15 am -
2 stops11h 42m
Mon 12/142:07 pm -
2 stops12h 29m
Deal found 11/3![Delta logo]()
$409
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:00 am -
1 stop7h 12m
Sun 12/136:30 am -
2 stops9h 51m
Deal found 10/31![United Airlines logo]()
$491
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:00 am -
1 stop7h 12m
Mon 12/1412:15 pm -
2 stops12h 11m
Deal found 11/3![United Airlines logo]()
$496
One-way flights from Medford to GreenvilleSearch for one-way flight options from Medford to Greenville. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
Search for one-way flight options from Medford to Greenville. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/109:26 pm -
3 stops19h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:21 pm -
2 stops13h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Delta logo]()
$338
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:00 am -
1 stop7h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![United Airlines logo]()
$389
Find flight deals from Medford to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $399 (United Airlines) |
One-way from | $310 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Medford to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
Use the filters below to find and compare flights from Medford to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Thu 12/10
9:26 pm-8:12 pm
3 stops19h 46m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$310
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Thu 12/10
5:21 pm-9:40 am
2 stops13h 19m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$338
Quickest round-trip
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Thu 12/10
5:00 am-3:12 pm
1 stop7h 12m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$389
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Thu 12/10
5:00 am-3:12 pm
1 stop7h 12m
Greenville
Sun 12/13
4:18 pm-9:26 pm
1 stop8h 08m
$399
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Fri 12/11
6:10 am-11:47 pm
2 stops14h 37m
Greenville
Mon 12/14
2:07 pm-11:36 pm
2 stops12h 29m
$409
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Wed 12/9
5:15 am-6:30 pm
2 stops10h 15m
Greenville
Mon 12/14
10:57 am-11:36 pm
2 stops15h 39m
$418
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Thu 12/10
5:15 am-7:57 pm
2 stops11h 42m
Greenville
Mon 12/14
2:07 pm-11:36 pm
2 stops12h 29m
$419
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Sat 12/5
5:00 am-3:12 pm
1 stop7h 12m
Greenville
Tue 12/8
6:30 am-1:21 pm
2 stops9h 51m
$534
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Sat 1/30
5:00 am-9:59 pm
2 stops13h 59m
Greenville
Wed 2/3
6:30 am-6:13 pm
2 stops14h 43m
$539
MedfordGreenville
MFR Medford - GSP Greenville
MFRGSP
Medford
Tue 2/9
6:00 am-7:07 pm
2 stops10h 07m
Greenville
Tue 2/23
10:28 am-9:30 pm
2 stops14h 02m
$539
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Medford to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to Greenville in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Medford-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Medford-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Medford to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Medford with our price prediction graph.
MFR-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Medford to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
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