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$493+ Cheap flights from Medford to Greenville (MFR - GSP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — GSP
Aug 5 — Aug 121
Wed 8/5
Wed 8/12
1 adult, Economy
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Cheap flight deals from Medford to Greenville

Cheapest flights from Medford to Greenville
Explore the most affordable flight options available from Medford to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 6, 2026.

This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:15 am
MFR
-
GSP
2 stops11h 15m
American Airlines
Thu 8/1310:12 am
GSP
-
MFR
2 stops12h 08m
American Airlines
Deal found 7/3$493
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:28 pm
MFR
-
GSP
2 stops12h 50m
Delta
Tue 8/255:46 am
GSP
-
MFR
2 stops10h 07m
Delta
Deal found 7/3$498
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:28 pm
MFR
-
GSP
2 stops12h 07m
United Airlines
Sun 8/234:33 pm
GSP
-
MFR
1 stop7h 35m
United Airlines
Deal found 7/3$567
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
MFR
-
GSP
2 stops14h 00m
United Airlines
Thu 8/134:33 pm
GSP
-
MFR
1 stop7h 35m
United Airlines
Deal found 7/3$579
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:20 am
MFR
-
GSP
2 stops12h 26m
American Airlines
Sun 8/235:30 am
GSP
-
MFR
2 stops10h 27m
American Airlines
Deal found 7/3$743
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:28 pm
MFR
-
GSP
2 stops12h 50m
Delta
Sun 8/95:20 pm
GSP
-
MFR
2 stops9h 35m
Delta
Deal found 7/3$759
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:00 am
MFR
-
GSP
2 stops13h 26m
United Airlines
Sun 8/94:15 pm
GSP
-
MFR
1 stop8h 02m
United Airlines
Deal found 7/3$802
This Priceline deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/207:50 pm
MFR
-
GSP
2 stops12h 11m
Alaska Airlines
Fri 7/2411:31 am
GSP
-
MFR
2 stops13h 49m
Alaska Airlines
Deal found 7/5$909
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:35 pm
MFR
-
GSP
2 stops13h 02m
United Airlines
Fri 7/244:15 pm
GSP
-
MFR
1 stop8h 01m
United Airlines
Deal found 7/5$961

Find flight deals from Medford to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 6, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$493
(American Airlines)
Provider with most accurate pricing for Medford-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Medford-Greenville flights.
Search Deals
From Medford to Greenville
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 6, 2026.
Use the filters below to find and compare flights from Medford to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Tue 8/18

5:28 pm-9:18 am

2 stops12h 50m

Greenville

Tue 8/25

5:46 am-12:53 pm

2 stops10h 07m

$498

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Fri 8/14

6:28 pm-9:35 am

2 stops12h 07m

Greenville

Sun 8/23

4:33 pm-9:08 pm

1 stop7h 35m

$567

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Sat 8/8

5:28 pm-9:18 am

2 stops12h 50m

Greenville

Sun 8/9

5:20 pm-11:55 pm

2 stops9h 35m

$759

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Mon 7/20

6:35 pm-10:37 am

2 stops13h 02m

Greenville

Fri 7/24

4:15 pm-9:16 pm

1 stop8h 01m

$961
Quickest round-trip

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Sat 8/8

5:00 am-3:19 pm

1 stop7h 19m

Greenville

Sun 8/9

4:15 pm-9:17 pm

1 stop8h 02m

$1,924

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/3

Sorted by cheapest first

Compare providers for flights from Medford to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to Greenville in July.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Medford-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Medford-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Medford to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Medford to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Medford to Greenville?

    For as low as $567, Delta can have you in Greenville from Medford in 12h 07m. There are 2230 mi between Medford and Greenville. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Medford to Greenville that include hotel bookings?

    Yes. In addition to deals on Medford to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Greenville.

  • Can I find deals for business class flights from Medford to Greenville?

    Yes. Cheapflights offers flight deals from Medford to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Greer
Simpsonville
Greenwood
Duncan
Seneca

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