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$104+ Cheap flights from Detroit to Greenville (DTT - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/29. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — GSP
oct. 17 — oct. 241
vie. 10/17
vie. 10/24
1 adult, Economy
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Cheap flight deals from Detroit to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 17, 2025.

Round-trip from

$256
(Kiwi.com)

One-way from

$104
(Kiwi.com)

Popular in

February

Cheapest in

May

Average price

$533

Good round-trip deal

$597 or less

Good one-way deal

$333 or less
From Detroit (DTT) to Greenville
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One-way flight from Detroit (DTT) to Greenville
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Highest demand for flights based on searches. 7% potential increase in price ($40 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Detroit (DTT) to Greenville.
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Price to beat on a one-way flight from Detroit (DTT) to Greenville.
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Find flight deals from Detroit to Greenville

Cheapest flights from Detroit to Greenville
Explore the most affordable flight options available from Detroit to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/269:39 amDTW - GSP
2 stops9h 07mMultiple Airlines
jue. 10/23:44 pmGSP - DTW
1 stop16h 56mMultiple Airlines
Deal found 9/16$256
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/269:39 amDTW - GSP
2 stops9h 07mMultiple Airlines
vie. 10/38:03 pmGSP - DTW
1 stop12h 37mMultiple Airlines
Deal found 9/16$260
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/269:39 amDTW - GSP
2 stops9h 07mMultiple Airlines
lun. 9/293:07 pmGSP - DTW
1 stop17h 08mMultiple Airlines
Deal found 9/16$263
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/184:50 pmDTW - GSP
1 stop22h 02mMultiple Airlines
mar. 10/214:18 pmGSP - DTW
1 stop23h 22mMultiple Airlines
Deal found 9/15$264
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/242:52 pmDTW - GSP
2 stops29h 52mMultiple Airlines
jue. 10/23:44 pmGSP - DTW
1 stop16h 56mMultiple Airlines
Deal found 9/16$278
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/239:19 pmDTW - GSP
2 stops37h 09mMultiple Airlines
jue. 10/23:44 pmGSP - DTW
1 stop16h 56mMultiple Airlines
Deal found 9/16$279
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/239:19 pmDTW - GSP
2 stops37h 09mMultiple Airlines
vie. 10/38:03 pmGSP - DTW
1 stop12h 37mMultiple Airlines
Deal found 9/16$282
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/247:35 pmDTW - GSP
1 stop14h 53mMultiple Airlines
vie. 10/38:03 pmGSP - DTW
1 stop12h 37mMultiple Airlines
Deal found 9/16$284
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/239:19 pmDTW - GSP
2 stops37h 09mMultiple Airlines
lun. 9/293:07 pmGSP - DTW
1 stop17h 08mMultiple Airlines
Deal found 9/16$285
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/162:53 pmDTW - GSP
1 stop28h 30mMultiple Airlines
jue. 10/234:47 pmGSP - DTW
1 stop15h 00mMultiple Airlines
Deal found 9/16$286

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
Use the filters below to find and compare flights from Detroit to Greenville that are best for you.

Fly from

Detroit

Fly to

Greenville

Route

Depart

Return

Price

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

mar. 9/23

9:19 pm-10:28 am

2 stops37h 09m

Greenville

vie. 10/3

8:03 pm-8:40 am

1 stop12h 37m

$282

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

jue. 10/2

3:42 pm-7:23 pm

2 stops27h 41m

Greenville

lun. 10/6

8:03 pm-11:48 am

1 stop15h 45m

$296

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

sáb. 12/13

11:34 am-8:12 pm

1 stop8h 38m

Greenville

mar. 1/13

7:55 am-5:15 pm

1 stop9h 20m

$322

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

vie. 12/12

12:56 pm-10:01 pm

1 stop9h 05m

Greenville

mar. 1/13

7:55 am-5:15 pm

1 stop9h 20m

$325

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

vie. 10/24

11:04 am-7:23 pm

1 stop8h 19m

Greenville

lun. 10/27

8:03 pm-6:44 pm

2 stops22h 41m

$334

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

sáb. 11/15

5:35 am-9:45 am

1 stop4h 10m

Greenville

sáb. 11/22

6:15 pm-12:25 am

2 stops6h 10m

$340

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

lun. 11/10

6:25 am-7:25 pm

2 stops13h 00m

Greenville

mar. 11/11

7:40 am-5:50 pm

2 stops10h 10m

$352

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

vie. 10/17

9:55 pm-2:48 pm

2 stops16h 53m

Greenville

dom. 10/19

9:53 pm-9:54 am

3 stops36h 01m

$370

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

sáb. 11/22

5:40 pm-10:35 pm

1 stop4h 55m

Greenville

mar. 11/25

7:40 am-12:10 pm

1 stop4h 30m

$376

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

lun. 10/13

5:25 am-9:55 am

1 stop4h 30m

Greenville

mié. 10/15

6:05 am-1:05 pm

1 stop7h 00m

$383

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 18 results
1
2

Best time to book a flight from Detroit to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Greenville

What is the cheapest month to book a flight from Detroit to Greenville?

Currently, August is the cheapest month in which you can book a flight from Detroit to Greenville (average of $321). Flying from Detroit to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTT to GSP?

Find hourly flight availability from Detroit to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 17, 2025.

When flying from Detroit to Greenville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 8% versus a flight in the morning.

What is the cheapest day to fly from Detroit to Greenville?

Use this chart to determine the cheapest time to fly round-trip from Detroit to Greenville. Price data was last updated on September 14, 2025.

Travelers seeking maximum savings on their Detroit to Greenville flight should consider departing on Friday mornings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Detroit to Greenville

Explore weekly flight availability from Detroit to Greenville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated septiembre 17, 2025.

The most flights from DTT to GSP are scheduled on a Monday (12 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated septiembre 17, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Detroit to Greenville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Detroit to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Detroit to Greenville?

    You will need to book a flight from Detroit All airports to Greenville if you want to fly from Detroit to Greenville. At least 3 different airlines have flights from All airports (DTT) to Greenville (GSP) on a regular basis. There are 10 flights to Greenville from the Detroit airport per day. If you manage to book one that is nonstop, then you can expect the flight time from DTT to GSP to be around 1h 35m.

  • How long is the flight from Detroit to Greenville?

    A quick flight from Detroit to Greenville can take about 8h 38m. American Airlines provides one of the quickest options available for as low as $322. The distance from Detroit to Greenville is about 510 mi.

  • What are the cheapest airlines flying from Detroit to Greenville round-trip?

    Currently priced at $236, American Airlines will fly you from Detroit to Greenville and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Southwest and Delta - these airlines can fly you to your destination from $323 and $397, respectively. Users have found that American Airlines is 50% cheaper than the other options available to this destination.

  • What are the most reliable airlines from Detroit to Greenville?

    Before booking your flight to Greenville from Detroit, check out the most reliable airlines to get you to your destination on time: Air France (88%), WestJet (84%), Korean Air( 84%).

  • What are the cheapest flights from Detroit to Greenville?

    Looking at all options, your cheapest flight can be booked for $288. While the most popular route (Detroit Metropolitan Wayne County - Greenville) can be booked for $287 on average, our data indicates $504 when flying from Detroit to Greenville.

  • Can I find deals for flights from Detroit to Greenville that include hotel bookings?

    Yes. In addition to deals on Detroit to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Greenville.

  • Can I find deals for business class flights from Detroit to Greenville?

    Yes. Cheapflights offers flight deals from Detroit to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit to Greenville?

    Currently, August is the cheapest month in which you can book a flight from Detroit to Greenville (average of $321). Flying from Detroit to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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Top 3 airlines flying from Detroit to Greenville

Discover the top 3 airlines that operate flights from Detroit to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$386FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$323Average$366FlexibilityNo cancel feeOn-time63%
DeltaCheapest$397Average$483FlexibilityNo cancel feeOn-timeN/A

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