$111+ Cheap flights from Detroit to Greenville (DTT - GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/29. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — GSP
Jul 4 — Jul 111
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Detroit to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to Greenville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Detroit to GreenvilleExplore the most affordable flight options available from Detroit to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 4, 2026.
Explore the most affordable flight options available from Detroit to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:00 am
DTW
- GSP
1 stop20h 57m
Multiple Airlines
Mon 8/244:55 pm
GSP
- DTW
1 stop20h 12m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:12 am
DTW
- GSP
1 stop22h 45m
Multiple Airlines
Sun 7/268:37 am
GSP
- DTW
1 stop28h 18m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:10 am
DTW
- GSP
2 stops25h 18m
Multiple Airlines
Mon 8/174:57 pm
GSP
- DTW
1 stop20h 10m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/712:50 pm
DTW
- GSP
2 stops43h 07m
Multiple Airlines
Mon 7/138:13 pm
GSP
- DTW
1 stop21h 42m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/89:12 am
DTW
- GSP
1 stop22h 45m
Multiple Airlines
Tue 7/1411:07 am
GSP
- DTW
1 stop6h 48m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:00 am
DTW
- GSP
1 stop20h 57m
Multiple Airlines
Sun 8/303:47 pm
GSP
- DTW
2 stops24h 53m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$307
Best flights from Detroit to GreenvilleDiscover carefully curated flight deals from Detroit to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 4, 2026.
Discover carefully curated flight deals from Detroit to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 4, 2026.
This Delta deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/258:40 am
DTW
- GSP
Nonstop1h 53m
Delta
Sun 12/66:20 pm
GSP
- DTW
Nonstop1h 53m
Delta
Deal found 6/1![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:10 am
DTW
- GSP
2 stops9h 05m
Southwest
Wed 8/267:00 am
GSP
- DTW
1 stop5h 55m
Southwest
Deal found 6/1![Southwest logo]()
$400
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:05 pm
DTW
- GSP
Nonstop1h 42m
Delta
Mon 7/137:10 am
GSP
- DTW
Nonstop1h 47m
Delta
Deal found 6/4![Delta logo]()
$399
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:45 pm
DTW
- GSP
Nonstop1h 41m
Delta
Sun 8/167:15 am
GSP
- DTW
Nonstop1h 47m
Delta
Deal found 5/30![Delta logo]()
$399
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:24 pm
DTW
- GSP
Nonstop1h 51m
Delta
Wed 8/267:07 pm
GSP
- DTW
Nonstop1h 53m
Delta
Deal found 5/30![Delta logo]()
$399
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/254:24 pm
DTW
- GSP
Nonstop1h 51m
Delta
Sun 8/3011:10 am
GSP
- DTW
Nonstop1h 48m
Delta
Deal found 6/3![Delta logo]()
$399
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:05 pm
DTW
- GSP
Nonstop1h 43m
Delta
Sat 7/412:46 pm
GSP
- DTW
Nonstop1h 53m
Delta
Deal found 5/30![Delta logo]()
$399
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/28:05 pm
DTW
- GSP
Nonstop1h 43m
Delta
Thu 7/95:16 pm
GSP
- DTW
1 stop3h 55m
Delta
Deal found 6/2![Delta logo]()
$409
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/84:21 pm
DTW
- GSP
Nonstop1h 51m
Delta
Tue 7/145:16 pm
GSP
- DTW
1 stop3h 55m
Delta
Deal found 6/4![Delta logo]()
$409
Last-minute flights from Detroit to GreenvilleDiscover last-minute flight deals from Detroit to Greenville. Data last updated June 4, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Greenville. Data last updated June 4, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/162:02 pm
DTW
- GSP
2 stops24h 56m
Multiple Airlines
Wed 7/83:48 pm
GSP
- DTW
1 stop21h 07m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/22:02 pm
DTW
- GSP
2 stops29h 31m
Multiple Airlines
Thu 7/93:19 pm
GSP
- DTW
1 stop21h 36m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/712:50 pm
DTW
- GSP
2 stops43h 07m
Multiple Airlines
Mon 7/138:13 pm
GSP
- DTW
1 stop21h 42m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/79:12 am
DTW
- GSP
1 stop29h 46m
Multiple Airlines
Sun 7/128:37 am
GSP
- DTW
1 stop28h 18m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/89:12 am
DTW
- GSP
1 stop22h 45m
Multiple Airlines
Tue 7/1411:07 am
GSP
- DTW
1 stop6h 48m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/99:12 am
DTW
- GSP
2 stops10h 27m
Multiple Airlines
Sun 7/123:35 pm
GSP
- DTW
1 stop21h 20m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:12 am
DTW
- GSP
1 stop22h 45m
Multiple Airlines
Sun 7/268:37 am
GSP
- DTW
1 stop28h 18m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:44 pm
DTW
- GSP
2 stops35h 51m
Multiple Airlines
Sun 8/28:37 am
GSP
- DTW
1 stop28h 18m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$319
One-way flights from Detroit to GreenvilleSearch for one-way flight options from Detroit to Greenville. Find affordable one-way fares based on user searches. Data last updated June 4, 2026.
Search for one-way flight options from Detroit to Greenville. Find affordable one-way fares based on user searches. Data last updated June 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2911:00 am
DTW
- GSP
1 stop20h 57m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3011:00 am
DTW
- GSP
1 stop29h 44m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:00 am
DTW
- GSP
1 stop20h 57m
Multiple Airlines
Deal found 5/30![Multiple Airlines logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/129:12 am
DTW
- GSP
1 stop11h 00m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/2311:00 am
DTW
- GSP
1 stop29h 05m
Multiple Airlines
Deal found 5/30![Multiple Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/299:12 am
DTW
- GSP
1 stop22h 45m
Multiple Airlines
Deal found 5/30![Multiple Airlines logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/269:12 am
DTW
- GSP
1 stop29h 29m
Multiple Airlines
Deal found 5/30![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/309:12 am
DTW
- GSP
1 stop10h 44m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/279:12 am
DTW
- GSP
2 stops10h 21m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/259:12 am
DTW
- GSP
1 stop22h 45m
Multiple Airlines
Deal found 5/30![Multiple Airlines logo]()
$135
Find flight deals from Detroit to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $211 (Kiwi.com) |
One-way from | $111 (Kiwi.com) |
Popular in | March |
Cheapest in | February |
Average price | $579 |
Good round-trip deal | $548 or less |
Good one-way deal | $333 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 4, 2026.
Use the filters below to find and compare flights from Detroit to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitGreenville
DTW - GSP
DTWGSP
Detroit Metropolitan Wayne County
Wed 11/25
8:40 am-10:33 am
Nonstop1h 53m
Greenville
Sun 12/6
6:20 pm-8:13 pm
Nonstop1h 53m
$399
DetroitGreenville
DTW - GSP
DTWGSP
Detroit Metropolitan Wayne County
Tue 7/7
8:05 pm-9:47 pm
Nonstop1h 42m
Greenville
Mon 7/13
7:10 am-8:57 am
Nonstop1h 47m
$399
Quickest round-trip
DetroitGreenville
DTW - GSP
DTWGSP
Detroit Metropolitan Wayne County
Thu 8/13
7:45 pm-9:26 pm
Nonstop1h 41m
Greenville
Sun 8/16
7:15 am-9:02 am
Nonstop1h 47m
$399
DetroitGreenville
DTW - GSP
DTWGSP
Detroit Metropolitan Wayne County
Fri 8/21
4:24 pm-6:15 pm
Nonstop1h 51m
Greenville
Wed 8/26
7:07 pm-9:00 pm
Nonstop1h 53m
$399
DetroitGreenville
DTW - GSP
DTWGSP
Detroit Metropolitan Wayne County
Tue 8/25
4:24 pm-6:15 pm
Nonstop1h 51m
Greenville
Sun 8/30
11:10 am-12:58 pm
Nonstop1h 48m
$399
DetroitGreenville
DTW - GSP
DTWGSP
Detroit Metropolitan Wayne County
Tue 6/30
8:05 pm-9:48 pm
Nonstop1h 43m
Greenville
Sat 7/4
12:46 pm-2:39 pm
Nonstop1h 53m
$399
DetroitGreenville
DTW - GSP
DTWGSP
Detroit Metropolitan Wayne County
Fri 8/21
11:10 am-8:15 pm
2 stops9h 05m
Greenville
Wed 8/26
7:00 am-12:55 pm
1 stop5h 55m
$400
DetroitGreenville
DTW - GSP
DTWGSP
Detroit Metropolitan Wayne County
Thu 7/2
8:05 pm-9:48 pm
Nonstop1h 43m
Greenville
Thu 7/9
5:16 pm-9:11 pm
1 stop3h 55m
$409
DetroitGreenville
DTW - GSP
DTWGSP
Detroit Metropolitan Wayne County
Wed 7/8
4:21 pm-6:12 pm
Nonstop1h 51m
Greenville
Tue 7/14
5:16 pm-9:11 pm
1 stop3h 55m
$409
Cheapest one-way
DetroitGreenville
DTW - GSP
DTWGSP
Detroit Metropolitan Wayne County
Mon 6/29
6:30 am-12:15 pm
1 stop5h 45m
$210
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Detroit to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Greenville in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Detroit with our price prediction graph.
DTT-GSP
DTW-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to Greenville
DTT-GSP
DTW-GSP
What is the cheapest month to book a flight from Detroit to Greenville?
Currently, September is the cheapest month in which you can book a flight from Detroit to Greenville (average of $236). Flying from Detroit to Greenville in July is currently the most expensive (average of $399). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTT to GSP?
Find hourly flight availability from Detroit to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 4, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Detroit to Greenville as you normally would.
How much does it cost to fly round-trip from Detroit to Greenville?
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated June 4, 2026.
Get a feel of what it's like to fly with Delta from Detroit to Greenville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Overall
7.9
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Overall
7.9
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Detroit to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Seneca
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Greenville flight routes
Other flight options
Other flights from Detroit
Popular flights
Alternative routes for Detroit to Greenville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Greenville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Detroit to Greenville by cabin class
Find flights from Detroit to Greenville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 4, 2026.
Detroit and Greenville flights
Browse other Detroit and Greenville flight options. Last updated on June 4, 2026.
Other flights from Detroit
Browse through other flights departing from Detroit. Flights are based on user searches made on Cheapflights and were last updated on June 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Detroit to Greenville
Discover the top 2 airlines that operate flights from Detroit to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$293 | Average$323 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$399 | Average$554 | FlexibilityNo cancel fee | On-timeN/A |