$104+ Cheap flights from Detroit to Greenville (DTT - GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/21. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — GSP
Sep 20 — Sep 271
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to Greenville
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Cheapest flights from Detroit to GreenvilleExplore the most affordable flight options available from Detroit to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
Explore the most affordable flight options available from Detroit to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/244:23 pm -
2 stops26h 00m
Mon 9/283:18 pm -
1 stop8h 09m
Deal found 8/21![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/294:29 pm -
1 stop15h 41m
Tue 11/311:28 am -
1 stop23h 34m
Deal found 8/19![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:23 pm -
2 stops17h 04m
Mon 10/58:32 pm -
1 stop15h 03m
Deal found 8/19![Multiple Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/214:23 pm -
1 stop24h 51m
Fri 9/252:18 pm -
1 stop9h 09m
Deal found 8/19![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/144:23 pm -
1 stop24h 51m
Mon 9/217:03 pm -
2 stops28h 24m
Deal found 8/17![Multiple Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/284:23 pm -
1 stop24h 51m
Sat 10/38:24 pm -
2 stops27h 03m
Deal found 8/21![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/294:23 pm -
2 stops27h 21m
Tue 10/612:29 pm -
1 stop10h 58m
Deal found 8/19![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/211:28 am -
1 stop6h 55m
Mon 10/57:03 pm -
2 stops28h 24m
Deal found 8/17![Multiple Airlines logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:37 am -
1 stop8h 07m
Wed 10/218:24 pm -
1 stop14h 28m
Deal found 8/16![Multiple Airlines logo]()
$244
Best flights from Detroit to GreenvilleDiscover carefully curated flight deals from Detroit to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
Discover carefully curated flight deals from Detroit to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:45 am -
2 stops10h 45m
Sun 11/18:15 am -
2 stops9h 00m
Deal found 8/17![Southwest logo]()
$398
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:45 pm -
Nonstop1h 42m
Sun 11/17:15 am -
Nonstop1h 47m
Deal found 8/17![Delta logo]()
$419
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:45 pm -
2 stops8h 00m
Mon 10/56:25 am -
2 stops10h 30m
Deal found 8/17![Southwest logo]()
$403
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:45 pm -
Nonstop1h 42m
Mon 10/196:57 pm -
Nonstop1h 51m
Deal found 8/17![Delta logo]()
$419
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:45 pm -
Nonstop1h 42m
Mon 11/96:59 pm -
Nonstop1h 56m
Deal found 8/18![Delta logo]()
$419
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:50 pm -
1 stop4h 25m
Tue 9/85:30 pm -
1 stop4h 05m
Deal found 8/16![Southwest logo]()
$460
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:29 am -
Nonstop1h 49m
Sun 10/117:15 am -
Nonstop1h 47m
Deal found 8/16![Delta logo]()
$419
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:20 am -
1 stop4h 44m
Mon 10/127:15 am -
Nonstop1h 47m
Deal found 8/20![Delta logo]()
$447
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:25 pm -
1 stop3h 56m
Mon 10/127:15 am -
Nonstop1h 47m
Deal found 8/20![Delta logo]()
$476
Last-minute flights from Detroit to GreenvilleDiscover last-minute flight deals from Detroit to Greenville. Data last updated August 21, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Greenville. Data last updated August 21, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/810:18 am -
2 stops33h 26m
Tue 9/1512:29 pm -
1 stop10h 58m
Deal found 8/17![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/144:23 pm -
1 stop24h 51m
Mon 9/217:03 pm -
2 stops28h 24m
Deal found 8/17![Multiple Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/154:23 pm -
2 stops27h 21m
Tue 9/2212:29 pm -
1 stop10h 58m
Deal found 8/18![Multiple Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/164:23 pm -
2 stops17h 04m
Mon 9/213:18 pm -
1 stop8h 09m
Deal found 8/20![Multiple Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:28 am -
1 stop5h 55m
Fri 9/257:03 pm -
2 stops28h 24m
Deal found 8/18![Multiple Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/214:23 pm -
1 stop24h 51m
Fri 9/252:18 pm -
1 stop9h 09m
Deal found 8/19![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/244:23 pm -
2 stops26h 00m
Mon 9/283:18 pm -
1 stop8h 09m
Deal found 8/21![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/284:23 pm -
1 stop24h 51m
Sat 10/38:24 pm -
2 stops27h 03m
Deal found 8/21![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/294:23 pm -
2 stops27h 21m
Tue 10/612:29 pm -
1 stop10h 58m
Deal found 8/19![Multiple Airlines logo]()
$237
One-way flights from Detroit to GreenvilleSearch for one-way flight options from Detroit to Greenville. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
Search for one-way flight options from Detroit to Greenville. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/214:23 pm -
1 stop24h 51m
Deal found 8/21![Multiple Airlines logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/114:29 pm -
1 stop16h 32m
Deal found 8/20![Multiple Airlines logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/144:23 pm -
1 stop24h 51m
Deal found 8/16![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/204:23 pm -
1 stop26h 07m
Deal found 8/18![Multiple Airlines logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/184:29 pm -
1 stop26h 01m
Deal found 8/17![Multiple Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:46 pm -
1 stop25h 03m
Deal found 8/16![Multiple Airlines logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:29 pm -
1 stop21h 45m
Deal found 8/17![Multiple Airlines logo]()
$123
Find flight deals from Detroit to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $204 (Kiwi.com) |
One-way from | $104 (Kiwi.com) |
Popular in | August |
Cheapest in | February |
Average price | $932 |
Good round-trip deal | $399 or less |
Good one-way deal | $333 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
Use the filters below to find and compare flights from Detroit to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Fri 10/30
10:45 am-9:30 pm
2 stops10h 45m
Greenville
Sun 11/1
8:15 am-5:15 pm
2 stops9h 00m
$398
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Fri 10/2
2:45 pm-10:45 pm
2 stops8h 00m
Greenville
Mon 10/5
6:25 am-4:55 pm
2 stops10h 30m
$403
Quickest round-trip
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Fri 10/30
7:45 pm-9:27 pm
Nonstop1h 42m
Greenville
Sun 11/1
7:15 am-9:02 am
Nonstop1h 47m
$419
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Thu 10/15
7:45 pm-9:27 pm
Nonstop1h 42m
Greenville
Mon 10/19
6:57 pm-8:48 pm
Nonstop1h 51m
$419
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Thu 11/5
7:45 pm-9:27 pm
Nonstop1h 42m
Greenville
Mon 11/9
6:59 pm-8:55 pm
Nonstop1h 56m
$419
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Wed 10/7
8:29 am-10:18 am
Nonstop1h 49m
Greenville
Sun 10/11
7:15 am-9:02 am
Nonstop1h 47m
$419
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Mon 10/5
6:20 am-11:04 am
1 stop4h 44m
Greenville
Mon 10/12
7:15 am-9:02 am
Nonstop1h 47m
$447
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Fri 9/4
3:50 pm-8:15 pm
1 stop4h 25m
Greenville
Tue 9/8
5:30 pm-9:35 pm
1 stop4h 05m
$460
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Fri 10/9
4:25 pm-8:21 pm
1 stop3h 56m
Greenville
Mon 10/12
7:15 am-9:02 am
Nonstop1h 47m
$476
Cheapest one-way
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Wed 2/17
6:15 am-12:45 pm
1 stop6h 30m
$159
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Detroit to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Greenville in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Detroit with our price prediction graph.
DTT-GSP
DTW-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to Greenville
DTT-GSP
DTW-GSP
What is the cheapest month to book a flight from Detroit to Greenville?
Currently, February is the cheapest month in which you can book a flight from Detroit to Greenville (average of $390). Flying from Detroit to Greenville in January is currently the most expensive (average of $693). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTT to GSP?
Find hourly flight availability from Detroit to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 21, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Detroit to Greenville as you normally would.
Weekly flight availability from Detroit to Greenville
Explore weekly flight availability from Detroit to Greenville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated August 21, 2026.
The most flights from DTT to GSP are scheduled on a Monday (14 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (4 on average).
How much does it cost to fly round-trip from Detroit to Greenville?
Airfare is below average for this route at the moment.
Detroit to Greenville flights typically cost between $508 and $867 in September.The cheapest round-trip price found within the last 5 days was $204 on Multiple Airlines (Sep 24-Sep 28).
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated August 21, 2026.
Get a feel of what it's like to fly with Delta from Detroit to Greenville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Comfort
7.8
Food
7.2
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Comfort
7.8
Food
7.2
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Related info for your journey
Find useful and relevant information for your journey from Detroit to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
Browse thousands of different options on Cheapflights for your next trip
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Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 21, 2026.
Detroit and Greenville flights
Browse other Detroit and Greenville flight options. Last updated on August 21, 2026.
Other flights from Detroit
Browse through other flights departing from Detroit. Flights are based on user searches made on Cheapflights and were last updated on August 21, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Detroit to Greenville
Discover the top 2 airlines that operate flights from Detroit to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$271 | Average$391 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$399 | Average$546 | FlexibilityNo cancel fee | On-timeN/A |