$145+ Cheap flights from Detroit to Greenville (DTT - GSP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/9. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — GSP
Dec 7 — Dec 141
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to Greenville
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Cheapest flights from Detroit to GreenvilleExplore the most affordable flight options available from Detroit to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 7, 2026.
Explore the most affordable flight options available from Detroit to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:29 pm -
1 stop15h 44m
Mon 11/168:52 pm -
2 stops26h 45m
Deal found 11/6![Multiple Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:30 am -
1 stop7h 59m
Tue 12/811:28 am -
2 stops50h 08m
Deal found 11/2![Multiple Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/99:33 pm -
2 stops11h 59m
Fri 12/118:52 pm -
1 stop26h 33m
Deal found 11/6![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:29 pm -
1 stop15h 44m
Thu 11/1910:12 am -
2 stops13h 25m
Deal found 11/5![Multiple Airlines logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/69:33 pm -
1 stop10h 40m
Sun 12/1310:12 am -
2 stops48h 59m
Deal found 11/6![Multiple Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
1 stop8h 58m
Tue 12/811:17 am -
1 stop10h 38m
Deal found 11/2![American Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:29 pm -
1 stop15h 44m
Mon 11/238:32 pm -
1 stop14h 00m
Deal found 11/4![Multiple Airlines logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/42:27 pm -
2 stops43h 35m
Fri 12/112:42 pm -
1 stop20h 39m
Deal found 11/4![Multiple Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:29 pm -
1 stop15h 44m
Tue 11/1711:28 am -
2 stops12h 09m
Deal found 11/5![Multiple Airlines logo]()
$333
Best flights from Detroit to GreenvilleDiscover carefully curated flight deals from Detroit to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 7, 2026.
Discover carefully curated flight deals from Detroit to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 7, 2026.
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2112:45 pm -
1 stop10h 40m
Mon 12/288:05 pm -
1 stop4h 10m
Deal found 11/6![Southwest logo]()
$449
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/48:15 pm -
Nonstop1h 43m
Sun 4/117:15 am -
Nonstop1h 51m
Deal found 11/3![Delta logo]()
$451
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:00 pm -
Nonstop1h 56m
Sun 12/277:21 am -
Nonstop1h 51m
Deal found 11/2![Delta logo]()
$451
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/44:35 pm -
Nonstop1h 55m
Mon 12/77:10 pm -
Nonstop1h 50m
Deal found 11/3![Delta logo]()
$451
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/23:55 pm -
Nonstop1h 46m
Sun 4/117:15 am -
Nonstop1h 51m
Deal found 11/3![Delta logo]()
$451
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/118:15 pm -
Nonstop1h 55m
Tue 1/197:13 am -
Nonstop1h 55m
Deal found 11/4![Delta logo]()
$461
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/244:02 pm -
Nonstop1h 54m
Tue 12/297:41 pm -
1 stop4h 01m
Deal found 11/5![Delta logo]()
$471
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/39:30 am -
1 stop5h 39m
Sun 4/116:20 pm -
Nonstop1h 53m
Deal found 11/5![Delta logo]()
$471
Last-minute flights from Detroit to GreenvilleDiscover last-minute flight deals from Detroit to Greenville. Data last updated November 7, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Greenville. Data last updated November 7, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:29 pm -
1 stop15h 44m
Thu 11/1910:12 am -
2 stops13h 25m
Deal found 11/5![Multiple Airlines logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:29 pm -
1 stop15h 44m
Mon 11/168:52 pm -
2 stops26h 45m
Deal found 11/6![Multiple Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:29 pm -
1 stop15h 44m
Tue 11/1711:28 am -
2 stops12h 09m
Deal found 11/5![Multiple Airlines logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:29 pm -
1 stop15h 44m
Mon 11/238:32 pm -
1 stop14h 00m
Deal found 11/4![Multiple Airlines logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:30 am -
1 stop7h 59m
Tue 12/811:28 am -
2 stops50h 08m
Deal found 11/2![Multiple Airlines logo]()
$270
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
1 stop8h 58m
Tue 12/811:17 am -
1 stop10h 38m
Deal found 11/2![American Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/42:27 pm -
2 stops43h 35m
Fri 12/112:42 pm -
1 stop20h 39m
Deal found 11/4![Multiple Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/69:33 pm -
1 stop10h 40m
Sun 12/1310:12 am -
2 stops48h 59m
Deal found 11/6![Multiple Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/99:33 pm -
2 stops11h 59m
Fri 12/118:52 pm -
1 stop26h 33m
Deal found 11/6![Multiple Airlines logo]()
$274
One-way flights from Detroit to GreenvilleSearch for one-way flight options from Detroit to Greenville. Find affordable one-way fares based on user searches. Data last updated November 7, 2026.
Search for one-way flight options from Detroit to Greenville. Find affordable one-way fares based on user searches. Data last updated November 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/910:03 pm -
2 stops40h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:41 am -
2 stops25h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:29 pm -
1 stop15h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/231:33 pm -
2 stops18h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$181
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/43:55 pm -
1 stop4h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Southwest logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:33 pm -
2 stops35h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$192
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/111:30 pm -
2 stops9h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Southwest logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2810:28 pm -
2 stops15h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Multiple Airlines logo]()
$222
Find flight deals from Detroit to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $204 (Kiwi.com) |
One-way from | $145 (Kiwi.com) |
Popular in | March |
Cheapest in | February |
Average price | $648 |
Good round-trip deal | $453 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 7, 2026.
Use the filters below to find and compare flights from Detroit to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Thu 11/19
5:30 am-10:45 am
1 stop5h 15m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$236
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Wed 11/25
7:43 pm-11:31 pm
1 stop3h 48m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$241
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Thu 11/12
2:55 pm-8:13 am
2 stops17h 18m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$248
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Sat 1/9
8:15 pm-10:10 pm
Nonstop1h 55m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$311
Quickest round-trip
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Wed 11/25
4:24 pm-6:10 pm
Nonstop1h 46m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$371
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Thu 11/12
8:25 am-10:11 am
Nonstop1h 46m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$374
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Wed 11/25
10:48 am-7:01 pm
2 stops8h 13m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$386
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Mon 12/21
12:45 pm-11:25 pm
1 stop10h 40m
Greenville
Mon 12/28
8:05 pm-12:15 am
1 stop4h 10m
$449
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Sun 4/4
8:15 pm-9:58 pm
Nonstop1h 43m
Greenville
Sun 4/11
7:15 am-9:06 am
Nonstop1h 51m
$451
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Wed 12/23
8:00 pm-9:56 pm
Nonstop1h 56m
Greenville
Sun 12/27
7:21 am-9:12 am
Nonstop1h 51m
$451
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Detroit to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Greenville in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Detroit with our price prediction graph.
DTT-GSP
DTW-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to Greenville
DTT-GSP
DTW-GSP
What is the cheapest month to book a flight from Detroit to Greenville?
Currently, February is the cheapest month in which you can book a flight from Detroit to Greenville (average of $390). Flying from Detroit to Greenville in January is currently the most expensive (average of $693). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTT to GSP?
Find hourly flight availability from Detroit to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 7, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Detroit to Greenville as you normally would.
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated November 7, 2026.
Get a feel of what it's like to fly with Delta from Detroit to Greenville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Food
7.2
Overall
7.8
Comfort
7.8
Crew
8.5
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Boarding
8.1
Entertainment
7.8
Food
7.2
Overall
7.8
Comfort
7.8
Crew
8.5
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Related info for your journey
Find useful and relevant information for your journey from Detroit to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
Browse thousands of different options on Cheapflights for your next trip
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Complete your trip to Greenville by adding a car rental and/or hotel reservation to your travel itinerary.
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Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 7, 2026.
Detroit and Greenville flights
Browse other Detroit and Greenville flight options. Last updated on November 7, 2026.
Other flights from Detroit
Browse through other flights departing from Detroit. Flights are based on user searches made on Cheapflights and were last updated on November 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Detroit to Greenville
Discover the top 2 airlines that operate flights from Detroit to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$271 | Average$366 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$399 | Average$480 | FlexibilityNo cancel fee | On-timeN/A |