HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Greenville

$89+ Cheap flights from Detroit to Greenville (DTT - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/14. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — GSP
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Detroit to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Detroit to Greenville

Cheapest flights from Detroit to Greenville
Explore the most affordable flight options available from Detroit to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:12 pmDTW - GSP
1 stop25h 11mMultiple Airlines
Mon 12/83:00 pmGSP - DTW
1 stop19h 08mMultiple Airlines
Deal found 11/19$227
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/159:18 amDTW - GSP
1 stop10h 05mMultiple Airlines
Thu 12/185:17 pmGSP - DTW
1 stop15h 34mMultiple Airlines
Deal found 11/18$237
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:15 amDTW - GSP
1 stop14h 59mMultiple Airlines
Sun 12/215:17 pmGSP - DTW
1 stop8h 02mMultiple Airlines
Deal found 11/19$250
This Mytrip deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:15 amDTW - GSP
1 stop14h 59mMultiple Airlines
Wed 12/244:40 pmGSP - DTW
1 stop7h 19mMultiple Airlines
Deal found 11/19$263
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:49 amDTW - GSP
2 stops13h 25mMultiple Airlines
Fri 12/128:03 pmGSP - DTW
1 stop15h 39mMultiple Airlines
Deal found 11/18$270
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/59:18 amDTW - GSP
1 stop10h 05mMultiple Airlines
Mon 12/83:00 pmGSP - DTW
1 stop19h 08mMultiple Airlines
Deal found 11/19$273
This Kiwi.com deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:54 pmDTW - GSP
1 stop13h 59mMultiple Airlines
Thu 12/2511:33 amGSP - DTW
1 stop6h 02mMultiple Airlines
Deal found 11/17$283
This Kiwi.com deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:01 pmDTW - GSP
2 stops25h 50mMultiple Airlines
Thu 12/2511:33 amGSP - DTW
1 stop8h 05mMultiple Airlines
Deal found 11/17$284
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/232:43 pmDTW - GSP
1 stop25h 07mMultiple Airlines
Tue 12/303:26 pmGSP - DTW
2 stops23h 08mMultiple Airlines
Deal found 11/19$293

Cheap flight deals from Detroit to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 20, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$220
(Kiwi.com)

One-way from

$89
(Kiwi.com)

Popular in

February

Cheapest in

May

Average price

$605

Good round-trip deal

$399 or less

Good one-way deal

$333 or less
Provider with most accurate pricing for Detroit (DTT)-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit (DTT)-Greenville flights.
Search Deals
From Detroit (DTT) to Greenville
Search Deals
One-way flight from Detroit (DTT) to Greenville
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($17 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from Detroit (DTT) to Greenville.
Search Deals
Price to beat on a one-way flight from Detroit (DTT) to Greenville.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Detroit to Greenville that are best for you.

Fly from

Detroit

Fly to

Greenville

Route

Depart

Return

Price

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Mon 12/22

6:15 am-9:14 pm

1 stop14h 59m

Greenville

Wed 12/24

4:40 pm-11:59 pm

1 stop7h 19m

$263

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Tue 1/27

5:25 am-10:40 am

1 stop5h 15m

Greenville

Tue 2/3

11:15 am-3:05 pm

1 stop3h 50m

$343

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Sat 12/13

5:35 am-9:45 am

1 stop4h 10m

Greenville

Tue 12/16

4:45 pm-10:35 pm

1 stop5h 50m

$355

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Fri 1/30

6:50 am-5:35 pm

2 stops10h 45m

Greenville

Wed 2/4

11:15 am-3:05 pm

1 stop3h 50m

$385

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Tue 12/30

3:55 pm-5:43 pm

Nonstop1h 48m

Greenville

Sat 1/3

6:00 am-7:52 am

Nonstop1h 52m

$399

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Tue 1/27

4:10 pm-6:04 pm

Nonstop1h 54m

Greenville

Tue 2/3

7:20 am-9:12 am

Nonstop1h 52m

$399

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Sat 12/20

8:20 pm-10:06 pm

Nonstop1h 46m

Greenville

Sun 12/21

7:30 am-9:22 am

Nonstop1h 52m

$399

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Sat 1/3

3:55 pm-5:43 pm

Nonstop1h 48m

Greenville

Sat 1/10

7:20 am-9:12 am

Nonstop1h 52m

$399

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Sun 1/18

5:59 pm-8:58 am

2 stops14h 59m

$139

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Wed 2/18

7:00 pm-4:27 pm

2 stops21h 27m

$150

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/18

Showing 1-10 of 18 results
1
2

Compare providers for flights from Detroit to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Greenville in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Detroit-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Detroit-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Greenville

What is the cheapest month to book a flight from Detroit to Greenville?

Currently, September is the cheapest month in which you can book a flight from Detroit to Greenville (average of $108). Flying from Detroit to Greenville in April is currently the most expensive (average of $201). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTT to GSP?

Find hourly flight availability from Detroit to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 20, 2025.

When flying from Detroit to Greenville, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 26% versus a flight in the evening.

What is the cheapest day to fly from Detroit to Greenville?

Use this chart to determine the cheapest time to fly round-trip from Detroit to Greenville. Price data was last updated on November 2, 2025.

Travelers seeking maximum savings on their Detroit to Greenville flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Detroit to Greenville?

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated November 20, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Detroit to Greenville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,002 reviews

Crew

8.5

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,002 reviews
Delta
7.9
Good
8,002 reviews

Crew

8.5

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,047 reviews
Delta
7.9
Good
8,002 reviews

Crew

8.5

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Detroit to Greenville?

    You will need to book a flight from Detroit All airports to Greenville if you want to fly from Detroit to Greenville. At least 3 different airlines have flights from All airports (DTT) to Greenville (GSP) on a regular basis. There are 9 flights to Greenville from the Detroit airport per day. If you manage to book one that is nonstop, then you can expect the flight time from DTT to GSP to be around 1h 43m.

  • How long is the flight from Detroit to Greenville?

    A quick flight from Detroit to Greenville can take about 5h 15m. Southwest provides one of the quickest options available for as low as $343. The distance from Detroit to Greenville is about 510 mi.

  • What are the cheapest airlines flying from Detroit to Greenville round-trip?

    Currently priced at $226, American Airlines will fly you from Detroit to Greenville and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Southwest and Delta - these airlines can fly you to your destination from $306 and $397, respectively. Users have found that American Airlines is 55% cheaper than the other options available to this destination.

  • What are the most reliable airlines from Detroit to Greenville?

    Before booking your flight to Greenville from Detroit, check out the most reliable airlines to get you to your destination on time: Endeavor Airlines (85%), Aeromexico (82%), Virgin Atlantic( 80%).

  • What are the cheapest flights from Detroit to Greenville?

    Looking at all options, your cheapest flight can be booked for $333. While the most popular route (Detroit Metropolitan Wayne County - Greenville) can be booked for $227 on average, our data indicates $401 when flying from Detroit to Greenville.

  • Can I find deals for flights from Detroit to Greenville that include hotel bookings?

    Yes. In addition to deals on Detroit to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Greenville.

  • Can I find deals for business class flights from Detroit to Greenville?

    Yes. Cheapflights offers flight deals from Detroit to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit to Greenville?

    Currently, September is the cheapest month in which you can book a flight from Detroit to Greenville (average of $108). Flying from Detroit to Greenville in April is currently the most expensive (average of $201). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Detroit to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to Charleston flights
O'Hare Intl to Charlotte flights
O'Hare Intl to Savannah flights
Detroit to Charlotte flights
Detroit to Charleston flights
Detroit to Myrtle Beach flights
Midway to Charlotte flights
O'Hare Intl to Greenville flights
Detroit to Savannah flights
O'Hare Intl to Myrtle Beach flights
Midway to Charleston flights
O'Hare Intl to Columbia flights
Midway to Savannah flights
Grand Rapids to Charlotte flights
South Bend to Charlotte flights
Grand Rapids to Myrtle Beach flights
Midway to Myrtle Beach flights
Grand Rapids to Charleston flights
Grand Rapids to Savannah flights
Detroit to Greenville flights
Detroit to Columbia flights
O'Hare Intl to Hilton Head Island flights
Midway to Greenville flights
Grand Rapids to Greenville flights
Midway to Columbia flights
O'Hare Intl to Augusta flights
Flint to Greenville flights
Traverse City to Savannah flights
Traverse City to Charleston flights
Detroit to Augusta flights
Flint to Savannah flights
Flint to Charleston flights
South Bend to Greenville flights
South Bend to Myrtle Beach flights
Grand Rapids to Hilton Head Island flights
Flint to Charlotte flights
Kalamazoo to Charlotte flights
South Bend to Savannah flights
Traverse City to Charlotte flights
South Bend to Charleston flights
Lansing to Myrtle Beach flights
Flint to Myrtle Beach flights
Kalamazoo to Savannah flights
Traverse City to Greenville flights
Detroit to Hilton Head Island flights
Midway to Augusta flights
Lansing to Greenville flights
Lansing to Charleston flights
Grand Rapids to Augusta flights
Lansing to Charlotte flights

Top 3 airlines flying from Detroit to Greenville

Discover the top 3 airlines that operate flights from Detroit to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$226Average$326FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$306Average$396FlexibilityNo cancel feeOn-time63%
DeltaCheapest$397Average$500FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.