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$188+ Cheap flights from Key Largo, FL to Gainesville (GNV)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — GNV
Dec 24 — Dec 311
Wed 12/24
Wed 12/31
1 adult, Economy
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Find flight deals from Key Largo to Gainesville

Cheapest flights from Key Largo to Gainesville
Explore the most affordable flight options available from Key Largo to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 24, 2025.

This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2710:35 pmMIA - GNV
Nonstop1h 24mAmerican Airlines
Mon 12/296:00 amGNV - MIA
Nonstop1h 18mAmerican Airlines
Deal found 11/24$368
This American Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2610:39 pmMIA - GNV
Nonstop1h 20mAmerican Airlines
Sat 11/296:00 amGNV - MIA
Nonstop1h 14mAmerican Airlines
Deal found 11/23$439
This American Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2510:39 pmMIA - GNV
Nonstop1h 20mAmerican Airlines
Fri 11/286:00 amGNV - MIA
Nonstop1h 14mAmerican Airlines
Deal found 11/21$440
This American Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2410:35 pmMIA - GNV
Nonstop1h 24mAmerican Airlines
Sat 12/276:00 amGNV - MIA
Nonstop1h 18mAmerican Airlines
Deal found 11/23$444
This American Airlines deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2510:39 pmMIA - GNV
Nonstop1h 20mAmerican Airlines
Sat 11/296:00 amGNV - MIA
Nonstop1h 14mAmerican Airlines
Deal found 11/22$460
This American Airlines deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2610:39 pmMIA - GNV
Nonstop1h 20mAmerican Airlines
Fri 11/286:00 amGNV - MIA
Nonstop1h 14mAmerican Airlines
Deal found 11/22$468
This American Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2910:39 pmMIA - GNV
Nonstop1h 20mAmerican Airlines
Sun 11/306:00 amGNV - MIA
Nonstop1h 14mAmerican Airlines
Deal found 11/23$485
This American Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1110:41 pmMIA - GNV
Nonstop1h 17mAmerican Airlines
Thu 12/186:00 amGNV - MIA
Nonstop1h 18mAmerican Airlines
Deal found 11/23$497
This American Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2110:35 pmMIA - GNV
Nonstop1h 24mAmerican Airlines
Sun 12/286:00 amGNV - MIA
Nonstop1h 18mAmerican Airlines
Deal found 11/23$514
This American Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2310:39 pmMIA - GNV
Nonstop1h 20mAmerican Airlines
Fri 11/286:00 amGNV - MIA
Nonstop1h 14mAmerican Airlines
Deal found 11/21$516
This American Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2310:39 pmMIA - GNV
Nonstop1h 20mAmerican Airlines
Thu 1/86:00 amGNV - MIA
Nonstop1h 17mAmerican Airlines
Deal found 11/21$528

Cheap flight deals from Key Largo to Gainesville

Keep the following information in mind while searching for Key Largo to Gainesville flight deals. Data was last updated November 24, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$347
(American Airlines)

One-way from

$188
(Delta)

Popular in

December

Cheapest in

August

Average price

$442
Provider with most accurate pricing for Miami-Gainesville Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Miami-Gainesville Regional flights.
Search Deals
From Key Largo to Gainesville Regional
Search Deals
One-way flight from Key Largo to Gainesville Regional
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key Largo to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 24, 2025.
Use the filters below to find and compare flights from Key Largo to Gainesville that are best for you.

Fly from

Key Largo

Fly to

Gainesville

Route

Depart

Return

Price

MiamiGainesville

MIA - GNV

MIAGNV

Miami

Fri 2/20

10:36 pm-11:57 pm

Nonstop1h 21m

Gainesville Regional

Sat 2/21

6:00 am-7:18 am

Nonstop1h 18m

$347

MiamiGainesville

MIA - GNV

MIAGNV

Miami

Wed 1/14

10:37 pm-11:57 pm

Nonstop1h 20m

Gainesville Regional

Sat 1/17

6:00 am-7:17 am

Nonstop1h 17m

$347

MiamiGainesville

MIA - GNV

MIAGNV

Miami

Thu 1/1

10:35 pm-11:59 pm

Nonstop1h 24m

Gainesville Regional

Sun 1/4

6:00 am-7:18 am

Nonstop1h 18m

$368

MiamiGainesville

MIA - GNV

MIAGNV

Miami

Sat 12/27

10:35 pm-11:59 pm

Nonstop1h 24m

Gainesville Regional

Mon 12/29

6:00 am-7:18 am

Nonstop1h 18m

$368

MiamiGainesville

MIA - GNV

MIAGNV

Miami

Sat 12/20

10:35 pm-11:59 pm

Nonstop1h 24m

Gainesville Regional

Sat 12/27

6:00 am-7:18 am

Nonstop1h 18m

$439

MiamiGainesville

MIA - GNV

MIAGNV

Miami

Wed 12/24

10:35 pm-11:59 pm

Nonstop1h 24m

Gainesville Regional

Sat 12/27

6:00 am-7:18 am

Nonstop1h 18m

$444

MiamiGainesville

MIA - GNV

MIAGNV

Miami

Thu 12/11

10:41 pm-11:58 pm

Nonstop1h 17m

Gainesville Regional

Sun 12/14

6:00 am-7:16 am

Nonstop1h 16m

$497

MiamiGainesville

MIA - GNV

MIAGNV

Miami

Thu 12/11

10:41 pm-11:58 pm

Nonstop1h 17m

Gainesville Regional

Thu 12/18

6:00 am-7:18 am

Nonstop1h 18m

$497

MiamiGainesville

MIA - GNV

MIAGNV

Miami

Thu 1/1

11:45 am-4:37 pm

1 stop4h 52m

Gainesville Regional

Sun 1/4

6:00 am-12:46 am

1 stop18h 46m

$514

MiamiGainesville

MIA - GNV

MIAGNV

Miami

Sun 12/21

10:35 pm-11:59 pm

Nonstop1h 24m

Gainesville Regional

Sun 12/28

6:00 am-7:18 am

Nonstop1h 18m

$514

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/23

Showing 1-10 of 20 results
1
2

Best time to book a flight from Key Largo to Gainesville

Have a flexible travel schedule? Discover the best time to fly to Gainesville from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Gainesville

What is the cheapest month to book a flight from Key Largo to Gainesville?

Currently, April is the cheapest month in which you can book a flight from Key Largo to Gainesville (average of $22). Flying from Key Largo to Gainesville in June is currently the most expensive (average of $73). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to GNV?

Find hourly flight availability from Key Largo to Gainesville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 24, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Key Largo to Gainesville as you normally would.

Reviews of airlines servicing Gainesville

Get insights into the airlines that provide service to Gainesville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Gainesville. Reviews last updated November 24, 2025.
Peruse reviews from past customers who have flown with American Airlines from Key Largo to Gainesville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,046 reviews

Boarding

7.5

Comfort

7.2

Crew

8.0

Entertainment

6.9

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
11,046 reviews
American Airlines
7.2
Good
11,046 reviews

Boarding

7.5

Comfort

7.2

Crew

8.0

Entertainment

6.9

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Gainesville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Gainesville from Key Largo?

    Most people fly into Gainesville Regional (GNV) if they book a flight to Gainesville from Key Largo. On average, Gainesville Regional has 2 inbound flights from Key Largo per day from 2 airlines. Gainesville Regional is conveniently located just 4.2 mi from Gainesville’s city center.

  • How long is the flight from Key Largo to Gainesville?

    Departing from Key Largo to Gainesville will take you 1h 21m. Airlines will cover a distance of 295 mi. All flights are typically nonstop.

  • What are the most reliable airlines from Key Largo to Gainesville?

    Before booking your flight to Gainesville from Key Largo, check out the most reliable airlines to get you to your destination on time: American Airlines (92%), Envoy Air (92%), Qatar Airways( 86%).

  • What are the cheapest flights from Key Largo to Gainesville?

    On average you can expect to pay $615 for a flight from Key Largo to Gainesville. The cheapest flight overall is $275 while the most popular route, (Miami - Gainesville Regional) is currently priced at $347.

  • Can I find deals for flights from Key Largo to Gainesville that include hotel bookings?

    Yes. In addition to deals on Key Largo to Gainesville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Gainesville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Gainesville.

  • Can I find deals for business class flights from Key Largo to Gainesville?

    Yes. Cheapflights offers flight deals from Key Largo to Gainesville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to Gainesville?

    Currently, April is the cheapest month in which you can book a flight from Key Largo to Gainesville (average of $22). Flying from Key Largo to Gainesville in June is currently the most expensive (average of $73). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Gainesville?

Book flights to Gainesville if you plan to visit one of these locations
Lake City
Alachua

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Top 2 airlines flying from Key Largo to Gainesville

Discover the top 2 airlines that operate flights from Key Largo to Gainesville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$227Average$1,277FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$347Average$445FlexibilityNo cancel feeOn-time71%

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