$81+ Cheap flights from Myrtle Beach (MYR) to Florida Keys
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/13. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — EYW
May 4 — May 111
1 adult, Economy
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Find cheap flights from Myrtle Beach to Florida Keys with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Florida Keys
Keep the following information in mind while searching for Myrtle Beach to Florida Keys flight deals. Data was last updated April 29, 2025.
Most accurate provider | CheapOair 3 stars |
|---|---|
Most trusted provider | CheapOair 3 stars |
Round-trip from | $194 (Mytrip) |
One-way from | $81 (Cheapflightsfares) |
Popular in | March |
Cheapest in | June |
Average price | $376 |
Find flight deals from Myrtle Beach to Florida Keys
Cheapest flights from Myrtle Beach to Florida KeysExplore the most affordable flight options available from Myrtle Beach to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.
Explore the most affordable flight options available from Myrtle Beach to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2410:35 amMYR - MIA
1 stop7h 44mMultiple Airlines
Sun 5/257:00 amMIA - MYR
1 stop9h 44mMultiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$194
This eDestinos deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/511:06 amMYR - MIA
1 stop6h 57mSpirit Airlines
Mon 5/127:00 amMIA - MYR
1 stop9h 44mSpirit Airlines
Deal found 4/28![Spirit Airlines logo]()
$223
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/217:18 amMYR - EYW
1 stop3h 59mAmerican Airlines
Tue 10/283:01 pmEYW - MYR
1 stop6h 25mAmerican Airlines
Deal found 4/29![American Airlines logo]()
$249
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/107:53 pmMYR - MIA
1 stop5h 04mDelta
Wed 6/187:22 pmMIA - MYR
1 stop4h 45mDelta
Deal found 4/28![Delta logo]()
$257
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/56:14 pmMYR - MIA
1 stop4h 08mAmerican Airlines
Sun 6/85:18 amMIA - MYR
1 stop4h 21mAmerican Airlines
Deal found 4/29![American Airlines logo]()
$313
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/97:15 amMYR - MIA
2 stops8h 30mSouthwest
Thu 6/1212:45 pmMIA - MYR
1 stop8h 50mSouthwest
Deal found 4/29![Southwest logo]()
$358
This CheapOair deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/123:36 pmMYR - MIA
1 stop19h 34mFrontier
Sat 6/1412:15 pmMIA - MYR
1 stop26h 26mFrontier
Deal found 4/28![Frontier logo]()
$363
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/145:32 pmMYR - EYW
2 stops23h 13mMultiple Airlines
Sun 5/184:06 pmEYW - MYR
2 stops28h 59mMultiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/141:24 pmMYR - EYW
1 stop6h 43mDelta
Sun 5/187:00 amEYW - MYR
1 stop5h 29mDelta
Deal found 4/28![Delta logo]()
$414
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/62:47 pmMYR - MIA
2 stops23h 24mUnited Airlines
Sat 9/137:28 amMIA - MYR
1 stop8h 59mUnited Airlines
Deal found 4/28![United Airlines logo]()
$466
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/85:16 pmMYR - EYW
2 stops24h 49mUnited Airlines
Sun 9/142:45 pmEYW - MYR
2 stops23h 57mUnited Airlines
Deal found 4/28![United Airlines logo]()
$520
This Booking.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/92:59 pmMYR - EYW
1 stop17h 08mBreeze Airways
Sun 10/1210:59 amEYW - MYR
1 stop21h 45mBreeze Airways
Deal found 4/29![Breeze Airways logo]()
$546
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Florida Keys that are best for you.
Fly from
Myrtle Beach
Fly to
Florida Keys
Route
Depart
Return
Price
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Sat 5/24
10:35 am-6:19 pm
1 stop7h 44m
Miami
Sun 5/25
7:00 am-4:44 pm
1 stop9h 44m
$194
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Sat 5/24
4:42 pm-4:33 pm
2 stops23h 51m
Miami
Sun 5/25
8:52 pm-7:25 pm
2 stops22h 33m
$250
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Tue 6/10
7:53 pm-12:57 am
1 stop5h 04m
Miami
Wed 6/18
7:22 pm-12:07 am
1 stop4h 45m
$257
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Thu 6/5
6:14 pm-10:22 pm
1 stop4h 08m
Miami
Sun 6/8
5:18 am-9:39 am
1 stop4h 21m
$313
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Mon 6/9
7:15 am-3:45 pm
2 stops8h 30m
Miami
Thu 6/12
12:45 pm-9:35 pm
1 stop8h 50m
$358
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Thu 6/12
3:36 pm-11:10 am
1 stop19h 34m
Miami
Sat 6/14
12:15 pm-2:41 pm
1 stop26h 26m
$363
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Wed 5/14
5:32 pm-4:45 pm
2 stops23h 13m
Key West
Sun 5/18
4:06 pm-9:05 pm
2 stops28h 59m
$369
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Wed 5/14
1:24 pm-8:07 pm
1 stop6h 43m
Key West
Sun 5/18
7:00 am-12:29 pm
1 stop5h 29m
$414
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Sat 9/6
2:47 pm-2:11 pm
2 stops23h 24m
Miami
Sat 9/13
7:28 am-4:27 pm
1 stop8h 59m
$466
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Sat 5/31
5:00 am-12:10 pm
1 stop7h 10m
Key West
Sat 6/7
3:55 pm-9:12 pm
1 stop5h 17m
$574
Showing 1-10 of 18 results
Best time to book a flight from Myrtle Beach to Florida Keys
Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Florida Keys
What is the cheapest month to book a flight from Myrtle Beach to Florida Keys?
Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Florida Keys (average of $328). Flying from Myrtle Beach to Florida Keys in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MYR to EOA?
Find hourly flight availability from Myrtle Beach to Florida Keys. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Myrtle Beach to Florida Keys as you normally would.
Rainfall in Florida Keys by month
Plan your trip to Florida Keys by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.
Temperature in Florida Keys by month
Plan your trip to Florida Keys by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).
Reviews of airlines servicing Florida Keys
Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated April 29, 2025.
To help decide which airline to fly from Myrtle Beach to Florida Keys, see what other customers have to say about Breeze Airways, Southwest and Delta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.3
Crew
8.8
Entertainment
6.6
Overall
8.1
Food
6.7
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Boarding
8.3
Crew
8.8
Entertainment
6.6
Overall
8.1
Food
6.7
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Boarding
8.3
Crew
8.8
Entertainment
6.6
Overall
8.1
Food
6.7
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Boarding
8.3
Crew
8.8
Entertainment
6.6
Overall
8.1
Food
6.7
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Boarding
8.3
Crew
8.8
Entertainment
6.6
Overall
8.1
Food
6.7
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Boarding
8.3
Crew
8.8
Entertainment
6.6
Overall
8.1
Food
6.7
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Myrtle Beach to Florida Keys
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from Myrtle Beach to Florida Keys
Discover the top 2 airlines that operate flights from Myrtle Beach to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$219 | Average$451 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$263 | Average$477 | FlexibilityNo cancel fee | On-time71% |