$102+ Cheap flights from Myrtle Beach (MYR) to Florida Keys
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/21. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — EYW
Jun 17 — Jun 241
1 adult, Economy
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Find cheap flights from Myrtle Beach to Florida Keys with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Florida Keys
Keep the following information in mind while searching for Myrtle Beach to Florida Keys flight deals. Data was last updated June 12, 2025.
Round-trip from | $181 (Cheapflightsfares) |
|---|---|
One-way from | $102 (FlightHub) |
Popular in | March |
Cheapest in | October |
Average price | $274 |
Find flight deals from Myrtle Beach to Florida Keys
Cheapest flights from Myrtle Beach to Florida KeysExplore the most affordable flight options available from Myrtle Beach to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.
Explore the most affordable flight options available from Myrtle Beach to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.
This Cheapflightsfares deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1912:18 pmMYR - MIA
1 stop6h 35mSpirit Airlines
Sun 9/287:00 amMIA - MYR
1 stop6h 47mSpirit Airlines
Deal found 6/11![Spirit Airlines logo]()
$181
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/11:25 pmMYR - EYW
1 stop6h 14mDelta
Thu 7/106:27 pmEYW - MYR
1 stop5h 32mDelta
Deal found 6/10![Delta logo]()
$224
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/17:00 amMYR - EYW
1 stop7h 08mAmerican Airlines
Thu 7/1011:18 amEYW - MYR
2 stops6h 08mAmerican Airlines
Deal found 6/10![American Airlines logo]()
$229
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:45 pmMYR - MIA
1 stop6h 07mDelta
Tue 11/188:05 amMIA - MYR
1 stop5h 23mDelta
Deal found 6/10![Delta logo]()
$235
This FlightHub deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/63:50 pmMYR - MIA
1 stop19h 30mMultiple Airlines
Fri 7/114:51 pmMIA - MYR
1 stop5h 47mMultiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$243
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/227:30 amMYR - EYW
1 stop9h 21mMultiple Airlines
Sun 8/248:53 amEYW - MYR
2 stops30h 15mMultiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$252
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/188:52 pmMYR - MIA
1 stop3h 39mAmerican Airlines
Sat 10/255:36 pmMIA - MYR
1 stop5h 55mAmerican Airlines
Deal found 6/10![American Airlines logo]()
$271
This Mytrip deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/129:51 pmMYR - EYW
1 stop13h 50mAllegiant Air
Sat 7/193:58 pmEYW - MYR
2 stops27h 52mAllegiant Air
Deal found 6/12![Allegiant Air logo]()
$287
This FlightHub deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/210:40 amMYR - MIA
1 stop9h 58mFrontier
Sun 8/109:42 pmMIA - MYR
1 stop22h 46mFrontier
Deal found 6/11![Frontier logo]()
$302
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/110:40 amMYR - MIA
2 stops9h 50mSouthwest
Tue 11/47:40 amMIA - MYR
1 stop6h 35mSouthwest
Deal found 6/10![Southwest logo]()
$308
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/52:05 pmMYR - MIA
1 stop8h 59mUnited Airlines
Tue 11/187:00 amMIA - MYR
3 stops30h 09mUnited Airlines
Deal found 6/12![United Airlines logo]()
$486
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1712:00 pmMYR - EYW
2 stops20h 00mUnited Airlines
Thu 7/36:45 pmEYW - MYR
2 stops19h 21mUnited Airlines
Deal found 6/9![United Airlines logo]()
$499
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Florida Keys that are best for you.
Fly from
Myrtle Beach
Fly to
Florida Keys
Route
Depart
Return
Price
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Fri 9/19
12:18 pm-6:53 pm
1 stop6h 35m
Miami
Sun 9/28
7:00 am-1:47 pm
1 stop6h 47m
$181
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Tue 7/1
1:25 pm-7:39 pm
1 stop6h 14m
Key West
Thu 7/10
6:27 pm-11:59 pm
1 stop5h 32m
$224
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Tue 7/1
7:00 am-2:08 pm
1 stop7h 08m
Key West
Thu 7/10
11:18 am-5:26 pm
2 stops6h 08m
$229
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Wed 11/5
6:45 pm-12:52 am
1 stop6h 07m
Miami
Tue 11/18
8:05 am-1:28 pm
1 stop5h 23m
$235
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Sun 7/6
3:50 pm-11:20 am
1 stop19h 30m
Miami
Fri 7/11
4:51 pm-10:38 pm
1 stop5h 47m
$243
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Fri 8/22
7:30 am-4:51 pm
1 stop9h 21m
Key West
Sun 8/24
8:53 am-3:08 pm
2 stops30h 15m
$252
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Fri 8/22
7:24 pm-11:48 pm
1 stop4h 24m
Miami
Tue 8/26
6:04 am-11:56 am
1 stop5h 52m
$272
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Sat 7/12
9:51 pm-11:41 am
1 stop13h 50m
Key West
Sat 7/19
3:58 pm-7:50 pm
2 stops27h 52m
$287
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Sat 8/2
10:40 am-8:38 pm
1 stop9h 58m
Miami
Sun 8/10
9:42 pm-8:28 pm
1 stop22h 46m
$302
Myrtle BeachMiami
MYR - MIA
MYRMIA
Myrtle Beach Intl
Sat 11/1
10:40 am-8:30 pm
2 stops9h 50m
Miami
Tue 11/4
7:40 am-2:15 pm
1 stop6h 35m
$308
Showing 1-10 of 21 results
Best time to book a flight from Myrtle Beach to Florida Keys
Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Florida Keys
What is the cheapest month to book a flight from Myrtle Beach to Florida Keys?
Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Florida Keys (average of $328). Flying from Myrtle Beach to Florida Keys in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MYR to EOA?
Find hourly flight availability from Myrtle Beach to Florida Keys. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Myrtle Beach to Florida Keys as you normally would.
Rainfall in Florida Keys by month
Plan your trip to Florida Keys by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.
Temperature in Florida Keys by month
Plan your trip to Florida Keys by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).
Reviews of airlines servicing Florida Keys
Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated June 12, 2025.
To help decide which airline to fly from Myrtle Beach to Florida Keys, see what other customers have to say about Breeze Airways, Southwest and Delta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.6
Boarding
8.3
Comfort
8.2
Food
6.7
Overall
8.1
Crew
8.8
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Boarding
8.3
Comfort
8.2
Food
6.7
Overall
8.1
Crew
8.8
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Boarding
8.3
Comfort
8.2
Food
6.7
Overall
8.1
Crew
8.8
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Boarding
8.3
Comfort
8.2
Food
6.7
Overall
8.1
Crew
8.8
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Boarding
8.3
Comfort
8.2
Food
6.7
Overall
8.1
Crew
8.8
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Boarding
8.3
Comfort
8.2
Food
6.7
Overall
8.1
Crew
8.8
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Myrtle Beach to Florida Keys
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from Myrtle Beach to Florida Keys
Discover the top 2 airlines that operate flights from Myrtle Beach to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$219 | Average$438 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$263 | Average$486 | FlexibilityNo cancel fee | On-time71% |