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Florida Keys

$105+ Cheap flights from Greenville (GSP) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/24. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — EYW
Dec 26 — Jan 21
Fri 12/26
Fri 1/2
1 adult, Economy
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Cheap flight deals from Greenville to Florida Keys

Keep the following information in mind while searching for Greenville to Florida Keys flight deals. Data was last updated November 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$179
(American Airlines)

One-way from

$105
(Southwest)

Popular in

December

Cheapest in

September

Average price

$431
Provider with most accurate pricing for Greenville-Miami flight deals.
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Provider most trusted by Cheapflights users for Greenville-Miami flights.
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From Greenville to Florida Keys
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One-way flight from Greenville to Florida Keys
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Highest demand for flights based on searches. 4% potential increase in price ($17 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Greenville to Florida Keys

Cheapest flights from Greenville to Florida Keys
Explore the most affordable flight options available from Greenville to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 26, 2025.

This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/912:17 pmGSP - EYW
1 stop5h 35mAmerican Airlines
Sat 12/132:36 pmEYW - GSP
1 stop7h 03mAmerican Airlines
Deal found 11/24$251
This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:44 pmGSP - EYW
1 stop6h 04mAmerican Airlines
Tue 12/98:05 pmEYW - GSP
1 stop3h 54mAmerican Airlines
Deal found 11/25$295
This Mytrip deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1910:41 amGSP - MIA
2 stops26h 25mMultiple Airlines
Tue 12/239:59 pmMIA - GSP
2 stops17h 51mMultiple Airlines
Deal found 11/26$310
This Kiwi.com deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/275:17 pmGSP - EYW
1 stop16h 00mMultiple Airlines
Sun 11/3012:15 pmEYW - GSP
1 stop26h 28mMultiple Airlines
Deal found 11/24$327
This Mytrip deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/123:00 pmGSP - MIA
2 stops20h 12mMultiple Airlines
Sun 12/144:08 pmMIA - GSP
2 stops22h 02mMultiple Airlines
Deal found 11/24$336
This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:44 pmGSP - EYW
1 stop6h 04mAmerican Airlines
Mon 12/88:05 pmEYW - GSP
1 stop3h 54mAmerican Airlines
Deal found 11/25$339
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2610:07 amGSP - EYW
1 stop3h 56mDelta
Wed 12/36:10 pmEYW - GSP
1 stop5h 30mDelta
Deal found 11/25$354
This American Airlines deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:04 pmGSP - MIA
Nonstop1h 59mAmerican Airlines
Mon 12/295:32 pmMIA - GSP
Nonstop2h 02mAmerican Airlines
Deal found 11/26$358
This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2611:33 amGSP - EYW
1 stop4h 40mAmerican Airlines
Wed 12/34:10 pmEYW - GSP
2 stops6h 54mAmerican Airlines
Deal found 11/25$359
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/95:10 amGSP - MIA
Nonstop2h 00mAmerican Airlines
Tue 12/910:04 amMIA - GSP
1 stop9h 05mAmerican Airlines
Deal found 11/24$361
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:02 amGSP - MIA
Nonstop2h 01mAmerican Airlines
Sun 1/410:49 pmMIA - GSP
Nonstop2h 02mAmerican Airlines
Deal found 11/24$391
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:07 pmGSP - MIA
Nonstop1h 58mAmerican Airlines
Wed 12/246:00 amMIA - GSP
1 stop4h 11mAmerican Airlines
Deal found 11/24$397

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Greenville to Florida Keys that are best for you.

Fly from

Greenville

Fly to

Florida Keys

Route

Depart

Return

Price

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Tue 1/27

6:50 am-10:40 am

1 stop3h 50m

Miami

Sat 1/31

11:59 am-6:14 pm

1 stop6h 15m

$199

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Sat 2/7

10:50 am-8:40 pm

2 stops9h 50m

Miami

Sat 2/14

8:00 am-12:20 pm

1 stop4h 20m

$249

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Sat 2/7

3:39 pm-9:47 pm

1 stop6h 08m

Key West

Thu 2/12

1:36 pm-6:59 pm

1 stop5h 23m

$249

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Sun 1/18

5:40 am-9:24 am

1 stop3h 44m

Miami

Sat 1/31

8:15 am-3:06 pm

1 stop6h 51m

$249

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Tue 1/20

11:15 am-9:00 pm

2 stops9h 45m

Miami

Thu 1/22

12:55 pm-5:35 pm

1 stop4h 40m

$249

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Tue 12/9

12:17 pm-5:52 pm

1 stop5h 35m

Key West

Sat 12/13

2:36 pm-9:39 pm

1 stop7h 03m

$251

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Fri 1/9

6:56 pm-8:59 pm

Nonstop2h 03m

Miami

Mon 1/12

4:26 pm-6:26 pm

Nonstop2h 00m

$280

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Mon 3/9

4:07 pm-12:21 pm

1 stop20h 14m

Key West

Fri 3/13

9:49 am-8:07 pm

1 stop10h 18m

$281

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Sat 3/7

6:19 pm-10:49 pm

1 stop4h 30m

Key West

Wed 3/11

1:38 pm-6:42 pm

1 stop5h 04m

$294

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Mon 1/26

12:09 pm-6:01 pm

1 stop5h 52m

Key West

Sun 2/1

7:45 pm-11:57 pm

1 stop4h 12m

$294

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/25

Showing 1-10 of 33 results
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Best time to book a flight from Greenville to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Florida Keys

What is the cheapest month to book a flight from Greenville to Florida Keys?

Currently, February is the cheapest month in which you can book a flight from Greenville to Florida Keys (average of $88). Flying from Greenville to Florida Keys in December is currently the most expensive (average of $109). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to EOA?

Find hourly flight availability from Greenville to Florida Keys. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 26, 2025.

It’s optimal to fly from Greenville to Florida Keys in the evening. By choosing this option you can save up to 74% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated November 26, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Greenville to Florida Keys by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,253 reviews

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,253 reviews
Southwest
8.0
Very good
4,253 reviews

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,998 reviews
Southwest
8.0
Very good
4,253 reviews

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,038 reviews
Southwest
8.0
Very good
4,253 reviews

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Allegiant Air
7.2
Good
700 reviews
Southwest
8.0
Very good
4,253 reviews

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Greenville to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Florida Keys?

    If you book a flight to Florida Keys from Greenville, you will be flying from Greenville, which is the city’s only airport. Greenville (GSP) is located 10.4 mi from the center of Greenville.

  • How long is the flight from Greenville to Florida Keys?

    There are many flights that can get you from Greenville to Florida Keys in 3h 50m. Fly via Delta, Southwest, or American Airlines to get the fastest option. The distance from Greenville to Florida Keys is about 639 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Greenville to Florida Keys one-way?

    To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $105. Allegiant Air flights start at $177 while deals on Breeze Airways start at $196 one-way.

  • Can I find deals for flights from Greenville to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Greenville to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Florida Keys.

  • Can I find deals for business class flights from Greenville to Florida Keys?

    Yes. Cheapflights offers flight deals from Greenville to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Florida Keys?

    Currently, February is the cheapest month in which you can book a flight from Greenville to Florida Keys (average of $88). Flying from Greenville to Florida Keys in December is currently the most expensive (average of $109). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Greenville to Florida Keys

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Top 2 airlines flying from Greenville to Florida Keys

Discover the top 2 airlines that operate flights from Greenville to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$376FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$253Average$400FlexibilityNo cancel feeOn-time71%

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