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Florida Keys

$122+ Cheap flights from Greenville (GSP) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — EYW
Nov 13 — Nov 201
Thu 11/13
Thu 11/20
1 adult, Economy
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Cheap flight deals from Greenville to Florida Keys

Keep the following information in mind while searching for Greenville to Florida Keys flight deals. Data was last updated October 14, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$179
(American Airlines)

One-way from

$122
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$419
Provider with most accurate pricing for Greenville-Miami flight deals.
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Provider most trusted by Cheapflights users for Greenville-Miami flights.
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From Greenville to Florida Keys
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One-way flight from Greenville to Florida Keys
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Highest demand for flights based on searches. 2% potential increase in price ($11 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Greenville to Florida Keys

Cheapest flights from Greenville to Florida Keys
Explore the most affordable flight options available from Greenville to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2025.

This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:35 amGSP - EYW
1 stop4h 52mDelta
Sat 11/16:17 pmEYW - GSP
1 stop4h 01mDelta
Deal found 10/13$259
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1911:34 amGSP - MIA
Nonstop1h 55mAmerican Airlines
Mon 11/249:02 amMIA - GSP
Nonstop2h 02mAmerican Airlines
Deal found 10/14$267
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1311:34 amGSP - MIA
Nonstop1h 55mAmerican Airlines
Tue 11/189:02 amMIA - GSP
Nonstop2h 02mAmerican Airlines
Deal found 10/14$272
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/45:00 amGSP - MIA
Nonstop1h 54mAmerican Airlines
Wed 11/129:55 pmMIA - GSP
Nonstop2h 04mAmerican Airlines
Deal found 10/14$277
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:30 amGSP - MIA
1 stop4h 05mDelta
Tue 11/116:23 pmMIA - GSP
1 stop5h 22mDelta
Deal found 10/14$297
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/11:39 pmGSP - MIA
1 stop9h 27mAmerican Airlines
Wed 11/510:01 amMIA - GSP
1 stop9h 00mAmerican Airlines
Deal found 10/13$300
This Breeze Airways deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/65:17 pmGSP - EYW
1 stop16h 00mBreeze Airways
Sun 11/910:59 amEYW - GSP
1 stop10h 15mBreeze Airways
Deal found 10/13$303
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:40 amGSP - MIA
2 stops12h 10mSouthwest
Mon 12/87:10 amMIA - GSP
2 stops8h 55mSouthwest
Deal found 10/13$307
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/510:35 amGSP - MIA
1 stop9h 50mSouthwest
Tue 11/116:55 amMIA - GSP
2 stops9h 10mSouthwest
Deal found 10/13$308
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/138:00 amGSP - MIA
2 stops14h 05mSouthwest
Tue 11/181:30 pmMIA - GSP
1 stop6h 10mSouthwest
Deal found 10/14$309
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/173:38 pmGSP - EYW
1 stop18h 29mMultiple Airlines
Sun 10/1910:59 amEYW - GSP
1 stop9h 45mMultiple Airlines
Deal found 10/13$310
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/117:40 amGSP - MIA
2 stops12h 10mSouthwest
Thu 11/1311:40 amMIA - GSP
2 stops9h 55mSouthwest
Deal found 10/13$318

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 14, 2025.
Use the filters below to find and compare flights from Greenville to Florida Keys that are best for you.

Fly from

Greenville

Fly to

Florida Keys

Route

Depart

Return

Price

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Wed 1/21

5:45 am-9:26 am

1 stop3h 41m

Miami

Tue 1/27

8:05 am-1:54 pm

1 stop5h 49m

$199

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Thu 2/5

2:12 pm-9:09 am

1 stop18h 57m

Key West

Sun 2/8

10:27 pm-8:59 pm

1 stop22h 32m

$249

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Tue 10/28

6:35 am-11:27 am

1 stop4h 52m

Key West

Sat 11/1

6:17 pm-10:18 pm

1 stop4h 01m

$259

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Tue 11/4

5:30 am-9:35 am

1 stop4h 05m

Miami

Wed 11/12

6:00 am-10:27 am

1 stop4h 27m

$297

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Wed 11/5

5:30 am-9:35 am

1 stop4h 05m

Miami

Tue 11/11

4:52 pm-11:45 pm

1 stop6h 53m

$297

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Thu 11/6

5:17 pm-9:17 am

1 stop16h 00m

Key West

Sun 11/9

10:59 am-9:14 pm

1 stop10h 15m

$303

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Thu 12/4

7:40 am-7:50 pm

2 stops12h 10m

Miami

Mon 12/8

7:10 am-4:05 pm

2 stops8h 55m

$307

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Mon 2/16

6:45 am-10:40 am

1 stop3h 55m

Miami

Sat 2/21

6:00 am-9:52 am

1 stop3h 52m

$315

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Thu 2/12

5:45 am-9:26 am

1 stop3h 41m

Miami

Tue 2/17

6:00 am-11:00 am

1 stop5h 00m

$315

GreenvilleMiami

GSP - MIA

GSPMIA

Greenville

Thu 2/12

6:45 am-10:40 am

1 stop3h 55m

Miami

Wed 2/18

8:05 am-1:54 pm

1 stop5h 49m

$315

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/12

Showing 1-10 of 31 results
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Best time to book a flight from Greenville to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Florida Keys

What is the cheapest month to book a flight from Greenville to Florida Keys?

Currently, November is the cheapest month in which you can book a flight from Greenville to Florida Keys (average of $87). Flying from Greenville to Florida Keys in December is currently the most expensive (average of $109). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to EOA?

Find hourly flight availability from Greenville to Florida Keys. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 14, 2025.

It’s optimal to fly from Greenville to Florida Keys in the evening. By choosing this option you can save up to 74% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated October 14, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Greenville to Florida Keys by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,235 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,235 reviews
Southwest
8.0
Very good
4,235 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,972 reviews
Southwest
8.0
Very good
4,235 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,043 reviews
Southwest
8.0
Very good
4,235 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Allegiant Air
7.2
Good
693 reviews
Southwest
8.0
Very good
4,235 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Greenville to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Florida Keys?

    If you book a flight to Florida Keys from Greenville, you will be flying from Greenville, which is the city’s only airport. Greenville (GSP) is located 10.4 mi from the center of Greenville.

  • How long is the flight from Greenville to Florida Keys?

    There are many flights that can get you from Greenville to Florida Keys in 3h 41m. Fly via Delta, Breeze Airways, or Southwest to get the fastest option. The distance from Greenville to Florida Keys is about 639 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Greenville to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Greenville to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Florida Keys.

  • Can I find deals for business class flights from Greenville to Florida Keys?

    Yes. Cheapflights offers flight deals from Greenville to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Florida Keys?

    Currently, November is the cheapest month in which you can book a flight from Greenville to Florida Keys (average of $87). Flying from Greenville to Florida Keys in December is currently the most expensive (average of $109). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Greenville to Florida Keys

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Top 2 airlines flying from Greenville to Florida Keys

Discover the top 2 airlines that operate flights from Greenville to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$393FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$253Average$397FlexibilityNo cancel feeOn-time71%

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