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Florence

$446+ Cheap flights from South Carolina to Florence (FLR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — FLR
Apr 5 — Apr 121
Sun 4/5
Sun 4/12
1 adult, Economy
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Cheap flight deals from South Carolina to Florence

Cheapest flights from South Carolina to Florence
Explore the most affordable flight options available from South Carolina to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 6, 2026.

This Air France deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:20 pm
CLT
-
FLR
2 stops15h 00m
Multiple Airlines
Tue 11/2412:15 pm
FLR
-
CLT
2 stops17h 38m
Multiple Airlines
Deal found 3/4$549
This Booking.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:50 pm
CLT
-
FLR
1 stop11h 45m
Lufthansa
Tue 11/248:00 am
FLR
-
CLT
1 stop14h 55m
Lufthansa
Deal found 3/4$566
This Mytrip deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:00 pm
CLT
-
FLR
2 stops33h 50m
Multiple Airlines
Tue 12/86:30 am
FLR
-
CLT
2 stops39h 49m
Multiple Airlines
Deal found 3/4$569
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:50 pm
CLT
-
FLR
1 stop16h 30m
American Airlines
Fri 8/217:05 am
FLR
-
CLT
1 stop15h 00m
American Airlines
Deal found 3/2$573
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/112:31 pm
CLT
-
FLR
2 stops14h 29m
United Airlines
Fri 8/216:30 am
FLR
-
CLT
2 stops18h 25m
United Airlines
Deal found 3/2$585
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:00 am
CLT
-
FLR
2 stops23h 00m
United Airlines
Thu 8/276:30 am
FLR
-
CLT
2 stops18h 25m
United Airlines
Deal found 3/3$586
This Rumbo deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:00 am
CLT
-
FLR
2 stops31h 05m
Scandinavian Airlines
Tue 5/57:55 pm
FLR
-
CLT
2 stops32h 16m
Scandinavian Airlines
Deal found 3/2$594
This American Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:11 pm
SAV
-
FLR
2 stops22h 09m
Multiple Airlines
Thu 4/2312:30 pm
FLR
-
SAV
2 stops17h 29m
Multiple Airlines
Deal found 3/1$864
This FlightHub deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:24 pm
SAV
-
FLR
2 stops22h 51m
Lufthansa
Tue 10/205:15 pm
FLR
-
SAV
2 stops36h 30m
Lufthansa
Deal found 3/1$865
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:50 pm
SAV
-
FLR
2 stops15h 10m
United Airlines
Tue 10/201:40 pm
FLR
-
SAV
2 stops26h 46m
United Airlines
Deal found 3/2$867
This Air France deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:51 pm
CHS
-
FLR
2 stops15h 34m
Multiple Airlines
Mon 4/2012:40 pm
FLR
-
CHS
2 stops16h 22m
Multiple Airlines
Deal found 3/2$939
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/122:58 pm
CHS
-
FLR
2 stops19h 37m
United Airlines
Sat 4/1810:45 am
FLR
-
CHS
2 stops42h 48m
United Airlines
Deal found 3/2$943

Find flight deals from South Carolina to Florence

Keep the following information in mind while searching for South Carolina to Florence flight deals. Data was last updated March 6, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$573
(American Airlines)

One-way from

$446
(oojo)
Provider with most accurate pricing for Myrtle Beach Intl-Florence Peretola flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Florence Peretola flights.
Search Deals
From South Carolina to Florence Peretola
Search Deals
One-way flight from South Carolina to Florence Peretola
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 6, 2026.
Use the filters below to find and compare flights from South Carolina to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Tue 8/11

2:31 pm-11:00 am

2 stops14h 29m

Florence Peretola

Fri 8/21

6:30 am-6:55 pm

2 stops18h 25m

$585

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Sun 8/16

6:00 am-11:00 am

2 stops23h 00m

Florence Peretola

Thu 8/27

6:30 am-6:55 pm

2 stops18h 25m

$586

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Tue 8/11

6:00 pm-10:20 pm

1 stop22h 20m

Florence Peretola

Fri 8/21

7:05 am-4:05 pm

1 stop15h 00m

$622

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Fri 4/17

11:45 pm-10:20 pm

1 stop16h 35m

Florence Peretola

Wed 4/22

7:05 am-6:41 pm

2 stops17h 36m

$718

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Fri 4/24

4:34 pm-10:20 pm

2 stops23h 46m

Florence Peretola

Sat 5/2

10:55 am-8:45 pm

1 stop15h 50m

$845

SavannahFlorence

SAV - FLR

SAVFLR

Savannah/Hilton Head

Tue 4/7

4:57 pm-11:30 am

2 stops36h 33m

Florence Peretola

Fri 4/17

7:55 pm-11:59 pm

2 stops34h 04m

$851

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Sat 4/11

5:40 pm-4:35 pm

2 stops40h 55m

Florence Peretola

Sat 4/18

10:45 am-8:57 pm

2 stops40h 12m

$856

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Wed 9/2

10:00 am-9:00 am

2 stops17h 00m

Florence Peretola

Sat 9/12

6:55 am-7:34 pm

2 stops18h 39m

$863

SavannahFlorence

SAV - FLR

SAVFLR

Savannah/Hilton Head

Thu 4/16

6:11 pm-10:20 pm

2 stops22h 09m

Florence Peretola

Thu 4/23

12:30 pm-11:59 pm

2 stops17h 29m

$864

CharlotteFlorence

CLT - FLR

CLTFLR

Charlotte Douglas

Wed 4/15

10:13 am-4:35 pm

2 stops24h 22m

Florence Peretola

Wed 4/22

1:40 pm-8:57 pm

3 stops37h 17m

$913

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/5

Showing 1-10 of 49 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Florence

What is the cheapest month to book a flight from South Carolina to Florence?

Currently, February is the cheapest month in which you can book a flight from South Carolina to Florence (average of $547). Flying from South Carolina to Florence in June is currently the most expensive (average of $1,303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from South Carolina?

    Florence Peretola (FLR), located 3.7 mi from the city center, is the airport you fly into when you book flights from South Carolina to Florence.

  • How long is the flight from South Carolina to Florence?

    A quick flight from South Carolina to Florence can take about 14h 29m. United Airlines provides one of the quickest options available for as low as $585. The distance between South Carolina and Florence is about 4684 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from South Carolina to Florence?

    The most popular route from South Carolina to Florence is Charlotte Douglas - Florence Peretola. You may also consider Charleston - Florence Peretola or Savannah/Hilton Head - Florence Peretola.

  • Can I find deals for flights from South Carolina to Florence that include hotel bookings?

    Yes. In addition to deals on South Carolina to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Florence.

  • Can I find deals for business class flights from South Carolina to Florence?

    Yes. Cheapflights offers flight deals from South Carolina to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Florence?

    Currently, February is the cheapest month in which you can book a flight from South Carolina to Florence (average of $547). Flying from South Carolina to Florence in June is currently the most expensive (average of $1,303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Pistoia
Arezzo

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Alternative routes for South Carolina to Florence

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from South Carolina to Florence

Discover the top 3 airlines that operate flights from South Carolina to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$547Average$1,210FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$576Average$1,104FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$591Average$950FlexibilityNo cancel feeOn-time76%

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