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$241+ Cheap flights from Seattle to Florence, SC (SEA - FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/13. Fares are subject to change and may not be available on all flights or dates of travel.
SEA — FLO
Mar 15 — Mar 221
Sun 3/15
Sun 3/22
1 adult, Economy
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Cheap flight deals from Seattle to Florence

Cheapest flights from Seattle to Florence
Explore the most affordable flight options available from Seattle to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.

This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2412:27 pm
SEA
-
FLO
1 stop7h 41m
American Airlines
Tue 3/316:15 am
FLO
-
SEA
1 stop8h 12m
American Airlines
Deal found 2/11$407
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/131:44 pm
SEA
-
FLO
1 stop7h 13m
American Airlines
Thu 3/195:16 am
FLO
-
SEA
1 stop10h 35m
American Airlines
Deal found 2/11$455
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:00 am
SEA
-
FLO
1 stop8h 50m
American Airlines
Tue 3/316:15 am
FLO
-
SEA
1 stop8h 12m
American Airlines
Deal found 2/11$527
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:00 am
SEA
-
FLO
1 stop8h 50m
American Airlines
Mon 3/25:16 am
FLO
-
SEA
1 stop10h 35m
American Airlines
Deal found 2/11$537
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:00 am
SEA
-
FLO
1 stop8h 50m
American Airlines
Tue 3/316:15 am
FLO
-
SEA
1 stop8h 12m
American Airlines
Deal found 2/11$551
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1111:28 pm
SEA
-
FLO
2 stops13h 22m
American Airlines
Sat 4/184:16 pm
FLO
-
SEA
2 stops11h 14m
American Airlines
Deal found 2/10$567
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1111:28 pm
SEA
-
FLO
2 stops13h 22m
American Airlines
Thu 4/165:24 am
FLO
-
SEA
1 stop10h 09m
American Airlines
Deal found 2/11$586

Find flight deals from Seattle to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Seattle (SEA) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$407
(American Airlines)

One-way from

$241
(American Airlines)

Popular in

April

Cheapest in

June

Average price

$502
Provider with most accurate pricing for Seattle/Tacoma Intl-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Seattle/Tacoma Intl-Florence flights.
Search Deals
From Seattle/Tacoma Intl to Florence
Search Deals
One-way flight from Seattle/Tacoma Intl to Florence
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($105 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($28 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Seattle to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Seattle to Florence that are best for you.

Fly from

Seattle

Fly to

Florence

Route

Depart

Return

Price

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Tue 3/24

7:21 am-11:08 pm

2 stops12h 47m

Florence

Tue 3/31

6:15 am-11:27 am

1 stop8h 12m

$412

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Fri 3/13

1:44 pm-11:57 pm

1 stop7h 13m

Florence

Thu 3/19

5:16 am-12:51 pm

1 stop10h 35m

$455

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Thu 2/26

6:00 am-5:50 pm

1 stop8h 50m

Florence

Mon 3/2

5:16 am-12:51 pm

1 stop10h 35m

$537

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Wed 3/25

7:00 am-11:57 pm

2 stops13h 57m

Florence

Tue 3/31

6:15 am-11:27 am

1 stop8h 12m

$562

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Sat 4/11

11:28 pm-3:50 pm

2 stops13h 22m

Florence

Sat 4/18

4:16 pm-12:30 am

2 stops11h 14m

$567

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Sat 4/11

11:28 pm-3:50 pm

2 stops13h 22m

Florence

Thu 4/16

5:24 am-12:33 pm

1 stop10h 09m

$586

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Thu 3/26

6:00 am-5:50 pm

1 stop8h 50m

Florence

Tue 3/31

6:15 am-5:52 pm

2 stops14h 37m

$586

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Sat 4/11

11:28 pm-3:50 pm

2 stops13h 22m

Florence

Fri 4/17

5:24 am-12:33 pm

1 stop10h 09m

$586

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Fri 3/13

1:44 pm-11:57 pm

1 stop7h 13m

$241

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Fri 4/10

11:28 pm-11:53 pm

2 stops21h 25m

$356

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/11

Showing 1-10 of 11 results
1
2
  • Most accurate provider: When it comes to deals on Seattle-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Seattle-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Seattle-Florence, South Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Seattle-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Seattle-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Seattle to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Seattle with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Seattle to Florence

What is the cheapest month to book a flight from Seattle to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Seattle to Florence, South Carolina (average of $178). Flying from Seattle to Florence, South Carolina in June is currently the most expensive (average of $307). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated February 13, 2026.
Read reviews from past customers who have flown American Airlines from Seattle to Florence. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,275 reviews

Crew

8.0

Comfort

7.2

Entertainment

6.9

Boarding

7.5

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,275 reviews
American Airlines
7.2
Good
11,275 reviews

Crew

8.0

Comfort

7.2

Entertainment

6.9

Boarding

7.5

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Seattle to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Seattle to Florence, South Carolina?

    There are many flights that can get you from Seattle to Florence, South Carolina in 12h 47m. Fly via American Airlines to get the fastest option. There are 2370 mi between Seattle and Florence, South Carolina.

  • What is the cheapest airline to fly from Seattle to Florence, South Carolina round-trip?

    According to our current data, American Airlines ($386), offers the cheapest pricing from Seattle to Florence, South Carolina. American Airlines is priced at 32% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Seattle to Florence that include hotel bookings?

    Yes. In addition to deals on Seattle to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Seattle to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Seattle to Florence.

  • Can I find deals for business class flights from Seattle to Florence?

    Yes. Cheapflights offers flight deals from Seattle to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Seattle to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Seattle to Florence, South Carolina (average of $178). Flying from Seattle to Florence, South Carolina in June is currently the most expensive (average of $307). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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Top airline flying from Seattle to Florence

Discover the top airline that operate flights from Seattle to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$386Average$531FlexibilityNo cancel feeOn-time71%

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