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$427+ Cheap flights from Seattle to Florence, SC (SEA - FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
SEA — FLO
May 19 — May 261
Tue 5/19
Tue 5/26
1 adult, Economy
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Cheap flight deals from Seattle to Florence

Cheapest flights from Seattle to Florence
Explore the most affordable flight options available from Seattle to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 19, 2026.

This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:50 am
SEA
-
FLO
1 stop8h 10m
American Airlines
Mon 6/85:05 am
FLO
-
SEA
1 stop7h 45m
American Airlines
Deal found 4/14$471
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:59 am
SEA
-
FLO
2 stops11h 51m
American Airlines
Tue 4/216:15 am
FLO
-
SEA
1 stop8h 13m
American Airlines
Deal found 4/16$512
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2411:55 pm
SEA
-
FLO
2 stops12h 55m
American Airlines
Wed 4/294:16 pm
FLO
-
SEA
1 stop7h 48m
American Airlines
Deal found 4/16$547
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/711:58 pm
SEA
-
FLO
2 stops11h 12m
American Airlines
Mon 6/222:35 pm
FLO
-
SEA
1 stop8h 39m
American Airlines
Deal found 4/15$602
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1810:50 am
SEA
-
FLO
1 stop8h 10m
American Airlines
Wed 7/85:17 am
FLO
-
SEA
1 stop7h 30m
American Airlines
Deal found 4/19$625

Find flight deals from Seattle to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Seattle (SEA) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 19, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$471
(American Airlines)

One-way from

$427
(American Airlines)

Popular in

April

Cheapest in

June

Average price

$892
Provider with most accurate pricing for Seattle/Tacoma Intl-Florence flight deals.
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Provider most trusted by Cheapflights users for Seattle/Tacoma Intl-Florence flights.
Search Deals
From Seattle/Tacoma Intl to Florence
Search Deals
One-way flight from Seattle/Tacoma Intl to Florence
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($116 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($35 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Seattle to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 19, 2026.
Use the filters below to find and compare flights from Seattle to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Wed 6/3

10:50 am-10:00 pm

1 stop8h 10m

Florence

Mon 6/8

5:05 am-9:50 am

1 stop7h 45m

$471

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Fri 4/24

11:55 pm-3:50 pm

2 stops12h 55m

Florence

Wed 4/29

4:16 pm-9:04 pm

1 stop7h 48m

$547

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Sun 6/7

11:58 pm-2:10 pm

2 stops11h 12m

Florence

Mon 6/22

2:35 pm-8:14 pm

1 stop8h 39m

$602
Cheapest one-way
Quickest one-way

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Tue 4/28

12:28 pm-10:42 pm

1 stop7h 14m

$427

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Mon 4/27

5:30 am-9:47 pm

2 stops13h 17m

$432

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Fri 4/24

12:59 am-3:50 pm

2 stops11h 51m

$432

SeattleFlorence

SEA - FLO

SEAFLO

Seattle/Tacoma Intl

Fri 4/24

10:29 pm-3:50 pm

1 stop14h 21m

$847

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Seattle-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Seattle-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Seattle-Florence, South Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Seattle-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Seattle-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Seattle to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Seattle with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Seattle to Florence

How much does it cost to fly round-trip from Seattle to Florence, South Carolina?

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated April 19, 2026.
Read reviews from past customers who have flown American Airlines from Seattle to Florence. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,619 reviews

Food

6.4

Entertainment

6.9

Crew

7.9

Comfort

7.2

Boarding

7.5

Overall

7.1

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.
American Airlines
7.1
Good
11,619 reviews
American Airlines
7.1
Good
11,619 reviews

Food

6.4

Entertainment

6.9

Crew

7.9

Comfort

7.2

Boarding

7.5

Overall

7.1

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.

Related info for your journey

Find useful and relevant information for your journey from Seattle to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Seattle to Florence, South Carolina?

    There are many flights that can get you from Seattle to Florence, South Carolina in 8h 10m. Fly via American Airlines to get the fastest option. There are 2370 mi between Seattle and Florence, South Carolina.

  • What is the cheapest airline to fly from Seattle to Florence, South Carolina round-trip?

    According to our current data, American Airlines ($386), offers the cheapest pricing from Seattle to Florence, South Carolina. American Airlines is priced at 33% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Seattle to Florence that include hotel bookings?

    Yes. In addition to deals on Seattle to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Seattle to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Seattle to Florence.

  • Can I find deals for business class flights from Seattle to Florence?

    Yes. Cheapflights offers flight deals from Seattle to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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Top airline flying from Seattle to Florence

Discover the top airline that operate flights from Seattle to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 19, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$386Average$621FlexibilityNo cancel feeOn-time71%

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