$148+ Cheap flights from Mississippi to Detroit Metropolitan Wayne County Airport (DTW)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/25. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — DTW
Oct 22 — Oct 291
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Mississippi to Detroit with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mississippi to Detroit
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mississippi to DetroitExplore the most affordable flight options available from Mississippi to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2026.
Explore the most affordable flight options available from Mississippi to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2026.
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/173:33 pm -
1 stop4h 27m
Sat 10/246:25 am -
1 stop4h 29m
Deal found 9/17![Delta logo]()
$291
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:45 pm -
1 stop4h 50m
Sat 10/244:11 pm -
1 stop7h 48m
Deal found 9/20![American Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:55 pm -
2 stops8h 40m
Tue 11/31:25 pm -
1 stop5h 10m
Deal found 9/19![Southwest logo]()
$330
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:55 pm -
2 stops8h 40m
Sat 10/246:20 am -
1 stop9h 25m
Deal found 9/20![Southwest logo]()
$336
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:25 am -
2 stops5h 55m
Sat 10/246:20 am -
1 stop9h 25m
Deal found 9/17![Southwest logo]()
$355
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:02 pm -
1 stop4h 17m
Sun 10/255:20 am -
1 stop4h 13m
Deal found 9/20![Delta logo]()
$371
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/259:21 am -
1 stop4h 33m
Fri 1/17:30 am -
1 stop6h 48m
Deal found 9/21![Delta logo]()
$375
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/141:46 pm -
1 stop6h 12m
Wed 10/216:46 pm -
1 stop4h 30m
Deal found 9/21![Delta logo]()
$385
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:25 am -
1 stop5h 30m
Tue 10/65:20 am -
1 stop4h 57m
Deal found 9/19![Delta logo]()
$391
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:30 am -
2 stops13h 25m
Fri 1/11:25 pm -
1 stop5h 10m
Deal found 9/18![Southwest logo]()
$397
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/81:55 pm -
1 stop7h 47m
Sat 12/128:35 am -
1 stop5h 45m
Deal found 9/17![United Airlines logo]()
$408
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:11 am -
1 stop5h 55m
Sun 10/116:00 am -
1 stop6h 13m
Deal found 9/21![American Airlines logo]()
$416
Best flights from Mississippi to DetroitDiscover carefully curated flight deals from Mississippi to Detroit that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 22, 2026.
Discover carefully curated flight deals from Mississippi to Detroit that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 22, 2026.
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/173:33 pm -
1 stop4h 27m
Sat 10/246:25 am -
1 stop4h 29m
Deal found 9/17![Delta logo]()
$291
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:55 pm -
2 stops8h 40m
Tue 11/31:25 pm -
1 stop5h 10m
Deal found 9/19![Southwest logo]()
$330
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/81:55 pm -
1 stop7h 47m
Sat 12/128:35 am -
1 stop5h 45m
Deal found 9/17![United Airlines logo]()
$408
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:11 am -
1 stop5h 55m
Sun 10/116:00 am -
1 stop6h 13m
Deal found 9/21![American Airlines logo]()
$416
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:45 pm -
2 stops39h 11m
Sun 10/256:41 pm -
1 stop15h 10m
Deal found 9/20![Multiple Airlines logo]()
$451
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:25 am -
2 stops5h 55m
Sat 10/246:20 am -
1 stop9h 25m
Deal found 9/17![Southwest logo]()
$355
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/259:21 am -
1 stop4h 33m
Fri 1/17:30 am -
1 stop6h 48m
Deal found 9/21![Delta logo]()
$375
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:00 pm -
1 stop7h 30m
Wed 10/2110:19 am -
2 stops10h 19m
Deal found 9/21![United Airlines logo]()
$425
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/16:30 am -
2 stops10h 30m
Mon 1/41:30 pm -
2 stops9h 35m
Deal found 9/21![Southwest logo]()
$412
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1712:10 pm -
1 stop7h 03m
Sun 2/217:45 pm -
1 stop4h 38m
Deal found 9/20![Delta logo]()
$421
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:00 am -
1 stop10h 23m
Sat 10/106:30 am -
1 stop10h 50m
Deal found 9/21![Multiple Airlines logo]()
$517
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/62:00 pm -
1 stop7h 30m
Sat 10/1010:25 am -
2 stops10h 13m
Deal found 9/20![United Airlines logo]()
$518
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/228:54 pm -
1 stop26h 47m
Sun 12/272:38 pm -
2 stops19h 13m
Deal found 9/19![Multiple Airlines logo]()
$529
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:30 am -
2 stops10h 25m
Wed 12/231:35 pm -
2 stops9h 45m
Deal found 9/20![Southwest logo]()
$487
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:00 pm -
1 stop7h 30m
Sun 10/116:15 am -
1 stop8h 10m
Deal found 9/22![United Airlines logo]()
$554
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:46 pm -
1 stop14h 57m
Fri 10/96:51 pm -
2 stops49h 14m
Deal found 9/20![Multiple Airlines logo]()
$654
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/243:55 pm -
1 stop6h 58m
Fri 11/278:00 am -
1 stop8h 25m
Deal found 9/21![American Airlines logo]()
$818
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/233:55 pm -
2 stops20h 05m
Sat 11/286:44 am -
2 stops9h 41m
Deal found 9/21![American Airlines logo]()
$1,282
Last-minute flights from Mississippi to DetroitDiscover last-minute flight deals from Mississippi to Detroit. Data last updated September 22, 2026 and is based on user searches.
Discover last-minute flight deals from Mississippi to Detroit. Data last updated September 22, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:08 am -
1 stop5h 47m
Sat 9/266:15 am -
1 stop8h 10m
Deal found 9/21![United Airlines logo]()
$425
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:25 am -
1 stop5h 30m
Tue 10/65:20 am -
1 stop4h 57m
Deal found 9/19![Delta logo]()
$391
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:11 am -
1 stop5h 55m
Sun 10/116:00 am -
1 stop6h 13m
Deal found 9/21![American Airlines logo]()
$416
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:14 am -
1 stop5h 26m
Tue 10/136:53 pm -
1 stop5h 32m
Deal found 9/18![American Airlines logo]()
$421
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:30 pm -
2 stops8h 08m
Sat 10/176:00 am -
1 stop6h 13m
Deal found 9/20![American Airlines logo]()
$437
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/141:46 pm -
1 stop6h 12m
Wed 10/216:46 pm -
1 stop4h 30m
Deal found 9/21![Delta logo]()
$385
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/173:33 pm -
1 stop4h 27m
Sat 10/246:25 am -
1 stop4h 29m
Deal found 9/17![Delta logo]()
$291
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:25 am -
2 stops5h 55m
Sat 10/246:20 am -
1 stop9h 25m
Deal found 9/17![Southwest logo]()
$355
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:45 pm -
1 stop4h 50m
Sat 10/244:11 pm -
1 stop7h 48m
Deal found 9/20![American Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:55 pm -
2 stops8h 40m
Sat 10/246:20 am -
1 stop9h 25m
Deal found 9/20![Southwest logo]()
$336
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:02 pm -
1 stop4h 17m
Sun 10/255:20 am -
1 stop4h 13m
Deal found 9/20![Delta logo]()
$371
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:55 pm -
2 stops8h 40m
Tue 11/31:25 pm -
1 stop5h 10m
Deal found 9/19![Southwest logo]()
$330
One-way flights from Mississippi to DetroitSearch for one-way flight options from Mississippi to Detroit. Find affordable one-way fares based on user searches. Data last updated September 22, 2026.
Search for one-way flight options from Mississippi to Detroit. Find affordable one-way fares based on user searches. Data last updated September 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:45 pm -
2 stops38h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$148
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:00 am -
1 stop7h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![American Airlines logo]()
$163
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2012:55 pm -
2 stops8h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Southwest logo]()
$168
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/161:04 pm -
1 stop7h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Delta logo]()
$188
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:25 am -
2 stops5h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Southwest logo]()
$204
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2612:00 pm -
1 stop7h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Delta logo]()
$209
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/263:35 pm -
2 stops7h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Southwest logo]()
$254
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:55 am -
2 stops10h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Southwest logo]()
$264
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:25 pm -
2 stops12h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Southwest logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:46 pm -
1 stop16h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$307
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:00 pm -
2 stops8h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Southwest logo]()
$311
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/275:49 pm -
1 stop5h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![American Airlines logo]()
$324
Find flight deals from Mississippi to Detroit
Keep the following information in mind while searching for Mississippi to Detroit flight deals. Data was last updated September 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $291 (Delta) |
One-way from | $163 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Mississippi to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 22, 2026.
Use the filters below to find and compare flights from Mississippi to Detroit Metropolitan Wayne County Airport that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
JacksonDetroit
JAN Jackson-Evers Intl - DTW Detroit Metropolitan Wayne County
JANDTW
Jackson-Evers Intl
Tue 10/20
5:02 pm-10:19 pm
1 stop4h 17m
Detroit Metropolitan Wayne County
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$163
JacksonDetroit
JAN Jackson-Evers Intl - DTW Detroit Metropolitan Wayne County
JANDTW
Jackson-Evers Intl
Mon 11/2
4:52 pm-11:52 pm
1 stop6h 00m
Detroit Metropolitan Wayne County
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$163
JacksonDetroit
JAN Jackson-Evers Intl - DTW Detroit Metropolitan Wayne County
JANDTW
Jackson-Evers Intl
Tue 10/20
12:55 pm-10:35 pm
2 stops8h 40m
Detroit Metropolitan Wayne County
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$168
GulfportDetroit
GPT Gulfport Biloxi Regional - DTW Detroit Metropolitan Wayne County
GPTDTW
Gulfport Biloxi Regional
Sun 10/25
7:45 pm-8:04 pm
3 stops23h 19m
Detroit Metropolitan Wayne County
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$188
JacksonDetroit
JAN Jackson-Evers Intl - DTW Detroit Metropolitan Wayne County
JANDTW
Jackson-Evers Intl
Mon 11/2
11:45 am-8:05 pm
2 stops7h 20m
Detroit Metropolitan Wayne County
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$204
JacksonDetroit
JAN Jackson-Evers Intl - DTW Detroit Metropolitan Wayne County
JANDTW
Jackson-Evers Intl
Sat 12/26
12:00 pm-8:20 pm
1 stop7h 20m
Detroit Metropolitan Wayne County
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$209
JacksonDetroit
JAN Jackson-Evers Intl - DTW Detroit Metropolitan Wayne County
JANDTW
Jackson-Evers Intl
Sat 12/26
3:35 pm-12:05 am
2 stops7h 30m
Detroit Metropolitan Wayne County
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$254
JacksonDetroit
JAN Jackson-Evers Intl - DTW Detroit Metropolitan Wayne County
JANDTW
Jackson-Evers Intl
Mon 10/19
5:55 am-4:55 pm
2 stops10h 00m
Detroit Metropolitan Wayne County
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$264
JacksonDetroit
JAN Jackson-Evers Intl - DTW Detroit Metropolitan Wayne County
JANDTW
Jackson-Evers Intl
Sat 10/17
3:33 pm-9:00 pm
1 stop4h 27m
Detroit Metropolitan Wayne County
Sat 10/24
6:25 am-9:54 am
1 stop4h 29m
$291
JacksonDetroit
JAN Jackson-Evers Intl - DTW Detroit Metropolitan Wayne County
JANDTW
Jackson-Evers Intl
Fri 10/16
12:00 pm-9:45 pm
2 stops8h 45m
Detroit Metropolitan Wayne County
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$311
Showing 1-10 of 31 resultsSorted by cheapest first
Best time to book a flight from Mississippi to Detroit
Have a flexible travel schedule? Discover the best time to fly to Detroit from Mississippi with our price prediction graph.
GPT-DTW
JAN-DTW
GLH-DTW
GTR-DTW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mississippi to Detroit Metropolitan Wayne County Airport
USMS-DTW
GPT-DTW
JAN-DTW
GLH-DTW
GTR-DTW
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Mississippi to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Detroit Metropolitan Wayne County Airport?
Book flights to Detroit Metropolitan Wayne County Airport if you plan to visit one of these locationsDearborn
Southfield
Sterling Heights
Troy
Auburn Hills
Pontiac
Warren
Rochester Hills
Livonia
Southgate
Romulus
Roseville
Allen Park
Ypsilanti
Plymouth
Fremont
Port Huron
Waterford
Utica
Madison Heights
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Detroit flight routes
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Mississippi to Detroit
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Detroit by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Detroit
Explore flights to Detroit departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 22, 2026.
Search flights from Mississippi to Detroit by cabin class
Find flights from Mississippi to Detroit, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Mississippi and Detroit flights
Browse other Mississippi and Detroit flight options. Last updated on September 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Mississippi to Detroit flights
Consider these flights traveling from Mississippi to Detroit.
Top 2 airlines flying from Mississippi to Detroit
Discover the top 2 airlines that operate flights from Mississippi to Detroit. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$253 | Average$435 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$342 | Average$406 | FlexibilityNo cancel fee | On-timeN/A |