What’s the cheapest layover airport for flights from Greenville to Detroit Metropolitan Wayne County Airport?

Chicago (ORD) is the most affordable 1-stop option, with an average round-trip price of $488.

Which airport typically offers the quickest layover for flights from Greenville to Detroit Metropolitan Wayne County Airport?

Flights via Chicago (ORD) offer the fastest connection on this route, with an average layover time of 0h 53m.

What’s the fastest layover option from Greenville to Detroit Metropolitan Wayne County Airport?

Flights via Baltimore (BWI) have the shortest average one-way travel time for 1-stop routes: 4h 05m.

What’s the top layover airport for flights from Greenville to Detroit Metropolitan Wayne County Airport?

Chicago (ORD) – chosen by Cheapflights users on 50% of 1-stop itineraries from Greenville to Detroit Metropolitan Wayne County Airport on Cheapflights.

Weekly flight availability from Greenville to Detroit Metropolitan Wayne County Airport

The most flights from GSP to DTW are scheduled on a Monday (6 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (3 on average).

In terms of precipitation, rainfall in Detroit Metropolitan Wayne County Airport ranges from 1.8 - 3.1 inches per month. August is typically the wettest month, when rainfall can reach 3.1 in. January is typically the driest time to visit Detroit Metropolitan Wayne County Airport when rainfall is around 1.8 in.

If weather is an important factor for your trip to Detroit Metropolitan Wayne County Airport, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

What are the most reliable airlines from Greenville to Detroit Metropolitan Wayne County Airport?

Consider Aeromexico (100%), KLM (92%) or Endeavor Airlines (90%) when booking your flight. These represent the most reliable airlines when flying from Greenville to Detroit Metropolitan Wayne County Airport.

What are the most popular airlines that fly from Greenville to Detroit Metropolitan Wayne County Airport?

The most popular airlines flying from Greenville to Detroit Metropolitan Wayne County Airport are Delta, American Airlines and Southwest. Something to consider prior to booking your flight.

Most accurate provider : When it comes to deals on Greenville-Detroit Metropolitan Wayne County Airport flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Greenville-Detroit Metropolitan Wayne County Airport flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Greenville-Detroit Metropolitan Wayne County Airport flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Greenville-Detroit Metropolitan Wayne County Airport flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Detroit Metropolitan Wayne County Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airports do I use to fly from Greenville to Detroit?

Detroit Metropolitan Wayne County is the airport most travelers will use when flying to Detroit from Greenville. Booking flights from Greenville (GSP) to Detroit Metropolitan Wayne County (DTW) should be relatively easy as there are 5 daily flights to Detroit from 3 different airlines. 1h 47m is how long a flight from Greenville to Detroit Metropolitan Wayne County will take if you book a nonstop flight.

Can I find deals for flights from Greenville to Detroit that include hotel bookings?

Yes. In addition to deals on Greenville to Detroit flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Greenville to Detroit?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Detroit.

Can I find deals for business class flights from Greenville to Detroit?

Yes. Cheapflights offers flight deals from Greenville to Detroit by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$102+ Flights from Greenville to Detroit Metropolitan Wayne County Airport

Q: How much does it cost to fly round-trip from Greenville to Detroit Metropolitan Wayne County Airport?

Airfare is below average for this route at the moment. Greenville to Detroit Metropolitan Wayne County Airport flights typically cost between $510 and $636 in January. The cheapest round-trip price found within the last 3 days was $205 on Multiple Airlines (Jan 30-Feb 1).

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Cheap flight deals from Greenville to Detroit

Cheapest flights from Greenville to Detroit
Explore the most affordable flight options available from Greenville to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Sun 12/2811:33 amGSP - DTW

1 stop7h 57mMultiple Airlines

Sat 1/1010:07 pmDTW - GSP

2 stops18h 12mMultiple Airlines

Deal found 12/26

$435

Tue 12/304:43 pmGSP - DTW

1 stop8h 36mMultiple Airlines

Thu 1/17:45 amDTW - GSP

2 stops13h 29mMultiple Airlines

Deal found 12/26

$561

Sun 12/2811:33 amGSP - DTW

1 stop21h 20mMultiple Airlines

Sun 1/42:09 pmDTW - GSP

1 stop29h 59mMultiple Airlines

Deal found 12/26

$581

Mon 12/297:25 pmGSP - DTW

1 stop14h 08mMultiple Airlines

Thu 1/17:45 amDTW - GSP

2 stops13h 29mMultiple Airlines

Deal found 12/24

$582

Mon 12/297:25 pmGSP - DTW

1 stop26h 31mMultiple Airlines

Fri 1/26:00 amDTW - GSP

1 stop13h 23mMultiple Airlines

Deal found 12/24

$592

Mon 12/296:23 pmGSP - DTW

Nonstop2h 00mDelta

Thu 1/19:15 pmDTW - GSP

2 stops14h 43mDelta

Deal found 12/24

$603

Mon 12/297:30 amGSP - DTW

Nonstop1h 52mDelta

Fri 1/23:55 pmDTW - GSP

Nonstop1h 48mDelta

Deal found 12/24

$619

Best flights from Greenville to Detroit
Discover carefully curated flight deals from Greenville to Detroit that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

Fri 1/239:49 pmGSP - DTW

1 stop11h 57mMultiple Airlines

Mon 1/266:35 amDTW - GSP

1 stop14h 24mMultiple Airlines

Deal found 12/25

$181

Tue 3/103:39 pmGSP - DTW

1 stop16h 26mDelta

Mon 3/309:55 pmDTW - GSP

1 stop13h 04mDelta

Deal found 12/26

$355

Sun 1/114:55 pmGSP - DTW

1 stop23h 26mMultiple Airlines

Thu 1/155:59 pmDTW - GSP

2 stops14h 59mMultiple Airlines

Deal found 12/26

$250

Mon 3/166:05 amGSP - DTW

1 stop16h 12mDelta

Sat 3/283:55 pmDTW - GSP

Nonstop1h 46mDelta

Deal found 12/26

$377

Wed 3/116:05 amGSP - DTW

1 stop16h 12mDelta

Fri 3/278:20 pmDTW - GSP

Nonstop1h 45mDelta

Deal found 12/26

$377

Mon 3/166:05 amGSP - DTW

1 stop16h 12mDelta

Thu 4/28:20 pmDTW - GSP

Nonstop1h 45mDelta

Deal found 12/26

$377

Mon 3/166:05 amGSP - DTW

1 stop16h 12mDelta

Sun 3/293:50 pmDTW - GSP

Nonstop1h 39mDelta

Deal found 12/26

$377

Thu 3/125:40 amGSP - DTW

1 stop5h 34mDelta

Tue 3/317:00 amDTW - GSP

1 stop10h 41mDelta

Deal found 12/26

$387

Sat 3/145:40 amGSP - DTW

1 stop3h 47mDelta

Wed 4/17:00 amDTW - GSP

1 stop14h 26mDelta

Deal found 12/26

$387

Sun 3/155:40 amGSP - DTW

1 stop3h 43mDelta

Tue 3/317:05 amDTW - GSP

2 stops12h 32mDelta

Deal found 12/26

$398

Wed 3/117:30 amGSP - DTW

Nonstop1h 44mDelta

Mon 3/303:50 pmDTW - GSP

Nonstop1h 39mDelta

Deal found 12/26

$399

Last-minute flights from Greenville to Detroit
Discover last-minute flight deals from Greenville to Detroit. Data last updated December 28, 2025 and is based on user searches.

Fri 1/99:48 amGSP - DTW

2 stops27h 42mMultiple Airlines

Sun 1/116:36 pmDTW - GSP

1 stop14h 22mMultiple Airlines

Deal found 12/27

$285

Sun 1/114:55 pmGSP - DTW

1 stop23h 26mMultiple Airlines

Thu 1/153:12 pmDTW - GSP

1 stop17h 46mMultiple Airlines

Deal found 12/26

$236

Fri 1/169:48 amGSP - DTW

1 stop12h 56mMultiple Airlines

Sat 1/176:36 pmDTW - GSP

1 stop21h 17mMultiple Airlines

Deal found 12/25

$268

Fri 1/239:49 pmGSP - DTW

1 stop11h 57mMultiple Airlines

Mon 1/266:35 amDTW - GSP

1 stop14h 24mMultiple Airlines

Deal found 12/25

$181

Fri 1/2312:37 pmGSP - DTW

1 stop10h 08mAmerican Airlines

Mon 1/2610:46 amDTW - GSP

1 stop8h 26mAmerican Airlines

Deal found 12/26

$337

Fri 1/304:39 pmGSP - DTW

1 stop7h 02mMultiple Airlines

Sun 2/11:43 pmDTW - GSP

1 stop19h 15mMultiple Airlines

Deal found 12/25

$205

One-way flights from Greenville to Detroit
Search for one-way flight options from Greenville to Detroit. Find affordable one-way fares based on user searches. Data last updated December 28, 2025.

Mon 2/238:18 pmGSP - DTW

1 stop12h 39mMultiple Airlines

Deal found 12/26

$102

Mon 1/264:39 pmGSP - DTW

1 stop18h 15mMultiple Airlines

Deal found 12/24

$107

Fri 1/234:07 pmGSP - DTW

1 stop17h 39mMultiple Airlines

Deal found 12/27

$111

Sun 1/256:45 pmGSP - DTW

2 stops23h 34mMultiple Airlines

Deal found 12/27

$114

Thu 2/262:12 pmGSP - DTW

1 stop20h 32mMultiple Airlines

Deal found 12/24

$118

Thu 1/226:45 pmGSP - DTW

2 stops23h 34mMultiple Airlines

Deal found 12/24

$119

Mon 3/26:49 pmGSP - DTW

1 stop14h 26mMultiple Airlines

Deal found 12/26

$122

Fri 2/276:49 pmGSP - DTW

1 stop14h 26mMultiple Airlines

Deal found 12/27

$127

Find flight deals from Greenville to Detroit

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$205 (Kiwi.com)
One-way from	$102 (Kiwi.com)
Popular in	August
Cheapest in	May
Average price	$728
Good round-trip deal	$399 or less
Good one-way deal	$193 or less

Provider with most accurate pricing for Greenville-Detroit Metropolitan Wayne County flight deals.

Search Deals

Provider most trusted by Cheapflights users for Greenville-Detroit Metropolitan Wayne County flights.

Search Deals

From Greenville to Detroit Metropolitan Wayne County

Search Deals

One-way flight from Greenville to Detroit Metropolitan Wayne County

Search Deals

Highest demand for flights based on searches. 4% potential increase in price ($24 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Greenville to Detroit Metropolitan Wayne County.

Search Deals

Price to beat on a one-way flight from Greenville to Detroit Metropolitan Wayne County.

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Greenville to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Fri 1/23

9:49 pm-9:46 am

1 stop11h 57m

Detroit Metropolitan Wayne County

Mon 1/26

6:35 am-8:59 pm

1 stop14h 24m

$181

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Sun 1/11

4:55 pm-4:21 pm

1 stop23h 26m

Detroit Metropolitan Wayne County

Thu 1/15

5:59 pm-8:58 am

2 stops14h 59m

$250

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Tue 3/10

3:39 pm-8:05 am

1 stop16h 26m

Detroit Metropolitan Wayne County

Mon 3/30

9:55 pm-10:59 am

1 stop13h 04m

$355

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Mon 3/16

6:05 am-10:17 pm

1 stop16h 12m

Detroit Metropolitan Wayne County

Sat 3/28

3:55 pm-5:41 pm

Nonstop1h 46m

$377

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Wed 3/11

6:05 am-10:17 pm

1 stop16h 12m

Detroit Metropolitan Wayne County

Fri 3/27

8:20 pm-10:05 pm

Nonstop1h 45m

$377

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Mon 3/16

6:05 am-10:17 pm

1 stop16h 12m

Detroit Metropolitan Wayne County

Thu 4/2

8:20 pm-10:05 pm

Nonstop1h 45m

$377

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Mon 3/16

6:05 am-10:17 pm

1 stop16h 12m

Detroit Metropolitan Wayne County

Sun 3/29

3:50 pm-5:29 pm

Nonstop1h 39m

$377

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Thu 3/12

5:40 am-11:14 am

1 stop5h 34m

Detroit Metropolitan Wayne County

Tue 3/31

7:00 am-5:41 pm

1 stop10h 41m

$387

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Sat 3/14

5:40 am-9:27 am

1 stop3h 47m

Detroit Metropolitan Wayne County

Wed 4/1

7:00 am-9:26 pm

1 stop14h 26m

$387

GreenvilleDetroit

GSP - DTW

GSPDTW

Greenville

Sun 3/15

5:40 am-9:23 am

1 stop3h 43m

Detroit Metropolitan Wayne County

Tue 3/31

7:05 am-7:37 pm

2 stops12h 32m

$398

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/26

Showing 1-10 of 18 results

Compare providers for flights from Greenville to Detroit

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Detroit in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Greenville-Detroit Metropolitan Wayne County Airport flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Greenville-Detroit Metropolitan Wayne County Airport flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Greenville-Detroit Metropolitan Wayne County Airport flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Greenville-Detroit Metropolitan Wayne County Airport flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Detroit Metropolitan Wayne County Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Detroit

Have a flexible travel schedule? Discover the best time to fly to Detroit from Greenville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Detroit Metropolitan Wayne County Airport

Prices

Airlines

What is the cheapest month to book a flight from Greenville to Detroit Metropolitan Wayne County Airport?

Currently, August is the cheapest month in which you can book a flight from Greenville to Detroit Metropolitan Wayne County Airport (average of $110). Flying from Greenville to Detroit Metropolitan Wayne County Airport in March is currently the most expensive (average of $200). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to DTW?

Unlike at noon, when flights are generally more expensive, you can save up to 44% on flights from Greenville to Detroit Metropolitan Wayne County Airport by exploring options for tickets in the morning.

How much does it cost to fly round-trip from Greenville to Detroit Metropolitan Wayne County Airport?

Reviews of airlines servicing Detroit

See what other customers who have flown with Southwest, Delta, and American Airlines from Greenville to Detroit Metropolitan Wayne County Airport have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

8.0

Very good

4,256 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,019 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,073 reviews

Southwest

8.0

Very good

4,256 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

What airports do I use to fly from Greenville to Detroit?
Detroit Metropolitan Wayne County is the airport most travelers will use when flying to Detroit from Greenville. Booking flights from Greenville (GSP) to Detroit Metropolitan Wayne County (DTW) should be relatively easy as there are 5 daily flights to Detroit from 3 different airlines. 1h 47m is how long a flight from Greenville to Detroit Metropolitan Wayne County will take if you book a nonstop flight.
How long is the flight from Greenville to Detroit Metropolitan Wayne County Airport?
For as low as $355, Delta can have you in Detroit Metropolitan Wayne County Airport from Greenville in 16h 26m. Airlines will cover a distance of 510 mi.
What are the cheapest airlines flying from Greenville to Detroit Metropolitan Wayne County Airport round-trip?
Cheapflights users have booked flights from Greenville to Detroit Metropolitan Wayne County Airport round-trip from $243. Other airlines that can offer you cheap pricing are American Airlines, from $278, and Delta, from $397. You may be able to fly from Greenville to Detroit Metropolitan Wayne County Airport for 53% less than the average price by searching for these airlines.
What are the most reliable airlines from Greenville to Detroit Metropolitan Wayne County Airport?
Consider Aeromexico (100%), KLM (92%) or Endeavor Airlines (90%) when booking your flight. These represent the most reliable airlines when flying from Greenville to Detroit Metropolitan Wayne County Airport.
What are the cheapest flights from Greenville to Detroit Metropolitan Wayne County Airport?
While on average a flight from Greenville to Detroit Metropolitan Wayne County Airport is generally $423, our data shows the cheapest flight currently is $101. When looking at the most popular route, (Greenville - Detroit Metropolitan Wayne County), you can expect to pay $205 for that flight.
Can I find deals for flights from Greenville to Detroit that include hotel bookings?
Yes. In addition to deals on Greenville to Detroit flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Greenville to Detroit?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Detroit.
Can I find deals for business class flights from Greenville to Detroit?
Yes. Cheapflights offers flight deals from Greenville to Detroit by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Greenville to Detroit Metropolitan Wayne County Airport?
Currently, August is the cheapest month in which you can book a flight from Greenville to Detroit Metropolitan Wayne County Airport (average of $110). Flying from Greenville to Detroit Metropolitan Wayne County Airport in March is currently the most expensive (average of $200). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Greenville to Detroit

Airline	Cheapest	Average	Flexibility	On-time
Southwest	Cheapest$243	Average$326	FlexibilityNo cancel fee	On-time63%
American Airlines	Cheapest$278	Average$392	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$397	Average$487	FlexibilityNo cancel fee	On-timeN/A

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$102+ Cheap flights from Greenville to Detroit Metropolitan Wayne County Airport (GSP - DTW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Greenville to Detroit with Cheapflights

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Cheap flight deals from Greenville to Detroit

Cheapest flights from Greenville to DetroitExplore the most affordable flight options available from Greenville to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Explore the most affordable flight options available from Greenville to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Find flight deals from Greenville to Detroit

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Greenville to Detroit Metropolitan Wayne County Airport that are best for you.

Compare providers for flights from Greenville to Detroit

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Detroit in December.

Best time to book a flight from Greenville to Detroit

Have a flexible travel schedule? Discover the best time to fly to Detroit from Greenville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Detroit Metropolitan Wayne County Airport

What is the cheapest month to book a flight from Greenville to Detroit Metropolitan Wayne County Airport?

What is the cheapest time of day to fly from GSP to DTW?

How much does it cost to fly round-trip from Greenville to Detroit Metropolitan Wayne County Airport?

Weekly flight availability from Greenville to Detroit Metropolitan Wayne County Airport

What’s the top layover airport for flights from Greenville to Detroit Metropolitan Wayne County Airport?

What’s the cheapest layover airport for flights from Greenville to Detroit Metropolitan Wayne County Airport?

What’s the fastest layover option from Greenville to Detroit Metropolitan Wayne County Airport?

Which airport typically offers the quickest layover for flights from Greenville to Detroit Metropolitan Wayne County Airport?

Reviews of airlines servicing Detroit

See what other customers who have flown with Southwest, Delta, and American Airlines from Greenville to Detroit Metropolitan Wayne County Airport have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from Greenville to Detroit?

How long is the flight from Greenville to Detroit Metropolitan Wayne County Airport?

What are the cheapest airlines flying from Greenville to Detroit Metropolitan Wayne County Airport round-trip?

What are the most reliable airlines from Greenville to Detroit Metropolitan Wayne County Airport?

What are the cheapest flights from Greenville to Detroit Metropolitan Wayne County Airport?

Can I find deals for flights from Greenville to Detroit that include hotel bookings?

How can I find direct flights from Greenville to Detroit?

Can I find deals for business class flights from Greenville to Detroit?

What is the cheapest month to book a flight from Greenville to Detroit Metropolitan Wayne County Airport?

Traveling to a place near Detroit Metropolitan Wayne County Airport?

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Alternative routes for Greenville to Detroit

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Greenville to Detroit

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Cheapest flights from Greenville to Detroit
Explore the most affordable flight options available from Greenville to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.