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$263+ Cheap flights from Florence, SC to Detroit Metropolitan Wayne County Airport (FLO - DTW)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — DTW
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Florence to Detroit

Cheapest flights from Florence to Detroit
Explore the most affordable flight options available from Florence to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2212:51 pmFLO - DTW
1 stop3h 35mAmerican Airlines
Wed 12/3111:56 amDTW - FLO
1 stop6h 09mAmerican Airlines
Deal found 12/15$362

Find flight deals from Florence to Detroit

Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Detroit (DTW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$263
(American Airlines)
Provider with most accurate pricing for Florence-Detroit Metropolitan Wayne County flight deals.
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Provider most trusted by Cheapflights users for Florence-Detroit Metropolitan Wayne County flights.
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From Florence to Detroit Metropolitan Wayne County
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Florence to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Florence

Fly to

Detroit

Route

Depart

Return

Price

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Wed 1/21

5:36 pm-10:30 pm

1 stop4h 54m

Detroit Metropolitan Wayne County

Tue 1/27

6:17 pm-10:43 pm

1 stop4h 26m

$263

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

  • Most accurate provider: When it comes to deals on Florence, South Carolina-Detroit Metropolitan Wayne County Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Florence, South Carolina-Detroit Metropolitan Wayne County Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Florence, South Carolina-Detroit Metropolitan Wayne County Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Florence, South Carolina-Detroit Metropolitan Wayne County Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Florence, South Carolina-Detroit Metropolitan Wayne County Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Florence to Detroit

Have a flexible travel schedule? Discover the best time to fly to Detroit from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Detroit Metropolitan Wayne County Airport

What is the cheapest month to book a flight from Florence, South Carolina to Detroit Metropolitan Wayne County Airport?

Currently, June is the cheapest month in which you can book a flight from Florence, South Carolina to Detroit Metropolitan Wayne County Airport (average of $71). Flying from Florence, South Carolina to Detroit Metropolitan Wayne County Airport in December is currently the most expensive (average of $150). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Florence to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Florence, South Carolina to Detroit Metropolitan Wayne County Airport?

    Departing from Florence, South Carolina to Detroit Metropolitan Wayne County Airport will take you 4h 54m. Florence, South Carolina and Detroit Metropolitan Wayne County Airport are separated by a distance of 589 mi.

  • Can I find deals for flights from Florence to Detroit that include hotel bookings?

    Yes. In addition to deals on Florence to Detroit flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Detroit?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Detroit.

  • Can I find deals for business class flights from Florence to Detroit?

    Yes. Cheapflights offers flight deals from Florence to Detroit by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Detroit Metropolitan Wayne County Airport?

    Currently, June is the cheapest month in which you can book a flight from Florence, South Carolina to Detroit Metropolitan Wayne County Airport (average of $71). Flying from Florence, South Carolina to Detroit Metropolitan Wayne County Airport in December is currently the most expensive (average of $150). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Detroit Metropolitan Wayne County Airport?

Book flights to Detroit Metropolitan Wayne County Airport if you plan to visit one of these locations
Sterling Heights
Dearborn
Southfield
Troy
Warren
Auburn Hills
Novi
Allen Park
Clarkston
Utica
Rochester Hills
Roseville
Romulus
Monroe
Wixom
Ypsilanti
Brighton
Livonia
Plymouth
Fremont

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