HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Detroit

$303+ Cheap flights from Florence, SC to Detroit Metropolitan Wayne County Airport (FLO - DTW)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — DTW
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Florence to Detroit with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Florence to Detroit

Cheapest flights from Florence to Detroit
Explore the most affordable flight options available from Florence to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/145:35 pmFLO - DTW
1 stop4h 16mAmerican Airlines
Fri 11/216:00 amDTW - FLO
1 stop4h 45mAmerican Airlines
Deal found 10/15$303
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/175:14 amFLO - DTW
1 stop3h 58mAmerican Airlines
Sun 10/196:00 amDTW - FLO
1 stop4h 46mAmerican Airlines
Deal found 10/15$359

Cheap flight deals from Florence to Detroit

Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Detroit (DTW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$303
(American Airlines)
Provider with most accurate pricing for Florence-Detroit Metropolitan Wayne County flight deals.
Search Deals
Provider most trusted by Cheapflights users for Florence-Detroit Metropolitan Wayne County flights.
Search Deals
From Florence to Detroit Metropolitan Wayne County
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Florence to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Florence

Fly to

Detroit

Route

Depart

Return

Price

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Fri 11/14

5:35 pm-9:51 pm

1 stop4h 16m

Detroit Metropolitan Wayne County

Fri 11/21

6:00 am-10:45 am

1 stop4h 45m

$303

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/15

Compare providers for flights from Florence to Detroit

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Florence to Detroit in October.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Florence, South Carolina-Detroit Metropolitan Wayne County Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Florence, South Carolina-Detroit Metropolitan Wayne County Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Florence, South Carolina-Detroit Metropolitan Wayne County Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Florence, South Carolina-Detroit Metropolitan Wayne County Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Florence, South Carolina-Detroit Metropolitan Wayne County Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Florence to Detroit

Have a flexible travel schedule? Discover the best time to fly to Detroit from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Detroit Metropolitan Wayne County Airport

What is the cheapest month to book a flight from Florence, South Carolina to Detroit Metropolitan Wayne County Airport?

Currently, June is the cheapest month in which you can book a flight from Florence, South Carolina to Detroit Metropolitan Wayne County Airport (average of $71). Flying from Florence, South Carolina to Detroit Metropolitan Wayne County Airport in December is currently the most expensive (average of $224). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Florence to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Florence, South Carolina to Detroit Metropolitan Wayne County Airport?

    Departing from Florence, South Carolina to Detroit Metropolitan Wayne County Airport will take you 4h 16m. Florence, South Carolina and Detroit Metropolitan Wayne County Airport are separated by a distance of 589 mi.

  • Can I find deals for flights from Florence to Detroit that include hotel bookings?

    Yes. In addition to deals on Florence to Detroit flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Detroit?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Detroit.

  • Can I find deals for business class flights from Florence to Detroit?

    Yes. Cheapflights offers flight deals from Florence to Detroit by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Detroit Metropolitan Wayne County Airport?

    Currently, June is the cheapest month in which you can book a flight from Florence, South Carolina to Detroit Metropolitan Wayne County Airport (average of $71). Flying from Florence, South Carolina to Detroit Metropolitan Wayne County Airport in December is currently the most expensive (average of $224). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Detroit Metropolitan Wayne County Airport?

Book flights to Detroit Metropolitan Wayne County Airport if you plan to visit one of these locations
Sterling Heights
Dearborn
Warren
Southfield
Troy
Novi
Clarkston
Allen Park
Utica
Romulus
Plymouth
Monroe
Wixom
Brighton
Livonia
Roseville
Fremont
Port Huron
Auburn Hills
Madison Heights

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.