Des Moines

$448+ Cheap flights from Prague (PRG) to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
PRG — DSM
ago. 3 — ago. 101
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Cheap flight deals from Prague to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Prague (PRG) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated julio 29, 2025.

Round-trip from

$888
(American Airlines)

One-way from

$448
(Kiwi.com)
From Václav Havel Prague to Des Moines
One-way flight from Václav Havel Prague to Des Moines

Find flight deals from Prague to Des Moines

Cheapest flights from Prague to Des Moines
Explore the most affordable flight options available from Prague to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 29, 2025.

This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/76:00 amPRG - DSM
2 stops19h 35mAmerican Airlines
mar. 11/116:00 pmDSM - PRG
2 stops16h 30mAmerican Airlines
Deal found 7/26$888
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/126:50 amPRG - DSM
2 stops34h 49mUnited Airlines
vie. 9/196:25 pmDSM - PRG
2 stops32h 15mUnited Airlines
Deal found 7/29$996

Cheapflights Fare Finder

 
Customize your flight search to find flights from Prague to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 29, 2025.
Use the filters below to find and compare flights from Prague to Des Moines that are best for you.

Fly from

Prague

Fly to

Des Moines

Route

Depart

Return

Price

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

vie. 11/7

6:00 am-6:35 pm

2 stops19h 35m

Des Moines

mar. 11/11

6:00 pm-5:30 pm

2 stops16h 30m

$888

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

vie. 9/12

6:50 am-10:39 am

2 stops34h 49m

Des Moines

vie. 9/19

6:25 pm-9:40 am

2 stops32h 15m

$996

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

mié. 9/17

6:50 pm-2:58 pm

3 stops51h 08m

$448

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

lun. 9/15

10:25 am-9:45 pm

2 stops18h 20m

$744

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

mar. 9/16

11:50 am-6:30 pm

2 stops37h 40m

$801

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

vie. 9/12

7:10 am-9:40 pm

2 stops21h 30m

$826

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

lun. 9/15

1:40 pm-9:45 pm

3 stops39h 05m

$1,183

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

vie. 9/12

11:00 am-11:51 am

1 stop31h 51m

$1,403

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Prague to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Prague with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated julio 29, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Prague to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
8.0
Very good
8.0
Very good

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
8.0
Very good

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
8.0
Very good

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
8.0
Very good

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
8.0
Very good

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.

Related info for your journey

Find useful and relevant information for your journey from Prague to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines flying from Prague to Des Moines round-trip?

    Currently priced at $888, American Airlines will fly you from Prague to Des Moines and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on United Airlines for as low as $996.

  • What are the cheapest airlines to fly from Prague to Des Moines one-way?

    To fly one-way, consider booking your trip with Lufthansa, which is currently one of the cheapest options available, starting at $744. Aer Lingus flights start at $801 while deals on American Airlines start at $826 one-way.

  • Can I find deals for flights from Prague to Des Moines that include hotel bookings?

    Yes. In addition to deals on Prague to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Prague to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Prague to Des Moines.

  • Can I find deals for business class flights from Prague to Des Moines?

    Yes. Cheapflights offers flight deals from Prague to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Prague to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Prague to Des Moines (average of $336). Flying from Prague to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Johnston
Boone
West Des Moines
Ankeny

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