HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$1,043+ Cheap flights from Prague (PRG) to Des Moines (DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
PRG — DSM
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Prague to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Prague to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Prague (PRG) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 11, 2025.

Round-trip from

$1,043
(Delta)
From Václav Havel Prague to Des Moines
Search Deals

Find flight deals from Prague to Des Moines

Cheapest flights from Prague to Des Moines
Explore the most affordable flight options available from Prague to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/276:00 amPRG - DSM
2 stops22h 01mDelta
mié. 10/12:49 pmDSM - PRG
2 stops19h 51mDelta
Deal found 9/11$1,043
This Air Canada deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/271:35 pmPRG - DSM
3 stops27h 57mAir Canada
mié. 10/11:00 pmDSM - PRG
3 stops17h 40mAir Canada
Deal found 9/11$1,725
This Air Canada deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/271:40 pmPRG - DSM
2 stops27h 52mMultiple Airlines
mié. 10/11:00 pmDSM - PRG
3 stops17h 40mMultiple Airlines
Deal found 9/11$1,859

Cheapflights Fare Finder

 
Customize your flight search to find flights from Prague to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Prague to Des Moines that are best for you.

Fly from

Prague

Fly to

Des Moines

Route

Depart

Return

Price

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

sáb. 9/27

6:00 am-9:01 pm

2 stops22h 01m

Des Moines

mié. 10/1

2:49 pm-5:40 pm

2 stops19h 51m

$1,043

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

sáb. 9/27

1:35 pm-10:32 am

3 stops27h 57m

Des Moines

mié. 10/1

1:00 pm-1:40 pm

3 stops17h 40m

$1,725

PragueDes Moines

PRG - DSM

PRGDSM

Václav Havel Prague

sáb. 9/27

1:40 pm-10:32 am

2 stops27h 52m

Des Moines

mié. 10/1

1:00 pm-1:40 pm

3 stops17h 40m

$1,859

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Best time to book a flight from Prague to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Prague with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Prague to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Prague to Des Moines?

    Delta and Air Canada can get you from Prague to Des Moines in just under 22h 01m. Your travel time can differ by up to 5h 56m. There are 4753 mi between Prague and Des Moines. This flight may include one or multiple stops.

  • Can I find deals for flights from Prague to Des Moines that include hotel bookings?

    Yes. In addition to deals on Prague to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Prague to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Prague to Des Moines.

  • Can I find deals for business class flights from Prague to Des Moines?

    Yes. Cheapflights offers flight deals from Prague to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Prague to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Prague to Des Moines (average of $336). Flying from Prague to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Prague to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
Prague to Cedar Rapids flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.